Page last updated: 2024-08-17

acetyl coenzyme a and pyruvic acid

acetyl coenzyme a has been researched along with pyruvic acid in 188 studies

Research

Studies (188)

TimeframeStudies, this research(%)All Research%
pre-199043 (22.87)18.7374
1990's30 (15.96)18.2507
2000's33 (17.55)29.6817
2010's69 (36.70)24.3611
2020's13 (6.91)2.80

Authors

AuthorsStudies
Diamond, LS; Gottlieb, M; Takeuchi, T; Weinbach, EC1
Herve, M; Tran-Dinh, S; Wietzerbin, J1
Russell, RR; Taegtmeyer, H1
Attwood, PV; Graneri, BD1
Knappe, J; Sawers, G1
Sahlin, K1
Liedtke, AJ; Nellis, SH; Renstrom, B1
Oppermann, FB; Schlegel, HG; Steinbüchel, A1
Marsac, C; Stansbie, D; Wallace, SJ1
Ogata, M; Yagi, T1
Takagi, D; Takeyama, N; Tanaka, T1
Chandramouli, V; Kosugi, K; Kumaran, K; Landau, BR; Schumann, WC; Scofield, RF1
Inui, H; Kitaoka, S; Miyatake, K; Nakano, Y; Ono, K1
Malaisse, WJ; Sener, A1
Akuffo, V; Costello, LC; Franklin, RB1
Di Donato, S; Garavaglia, B; Uziel, G1
Dynnik, VV; Kosenko, EA; Maevsky, EI1
Dry, IB; Wiskich, JT1
Consoli, A; Gerich, J; Kennedy, F; Miles, J1
Attwood, PV; Mayer, F; Wallace, JC1
Attwood, PV; Goodall, GJ; Keech, DB; Phillips, NB; Snoswell, MA; Wallace, JC1
Agius, L; Vaartjes, WJ1
Inui, H; Kitaoka, S; Miyatake, K; Nakano, Y1
Hartzell, CR; Johnson, GV1
Allan, EH; Chisholm, AB; Titheradge, MA1
Best, L; Malaisse, WJ; Malaisse-Lagae, F; Sener, A1
Gilbert, RJ; Klein, RA; Miller, PG1
Loh, WH; Miller, RH; Randles, CI; Sharp, WR1
Geelen, MJ1
Sheehan, PM; Yeh, YY1
Debuysere, MS; Olson, MS; Patel, TB; Scholz, R1
Danson, MJ; Hale, G; Perham, RN1
Frey, PA1
Abou-Jaoudé, A; Blaschkowski, HP; Chippaux, M; Knappe, J; Pascal, MC1
Barclay, L; Blass, J; Gibson, G1
Greksák, M; Lopes-Cardozo, M; van den Bergh, SG1
Bielarczyk, H; Kabata, J; Szutowicz, A1
George, HA; Smibert, RM1
Popova, SV; Reich, JG1
Murphy, DJ; Stumpf, PK1
Forgo, P; Kover, KE; Podanyi, B; Sumegi, B1
Attwood, PV; Branson, JP; Geeves, MA1
Jankowska, A; Kisielevski, Y; Szutowicz, A; Tomaszewicz, M1
Corkey, BE; Curtiss, D; Kilpatrick, L; Nachiappan, V1
He, JY; Liu, K; Vining, LC; White, RL1
Katz, J; Lee, WN; Wals, P1
Beeckmans, S; Kanarek, L; Khan, AS; Van Driessche, E1
Besson, C; Demigne, C; Morand, C; Remesy, C1
Argilés, JM; Domènech, M; López-Soriano, FJ1
Curi, R; Hirata, MH; Homem de Bittencourt, PI; Peres, CM; Yano, MM1
Lindsay, JG; Miller, C; Sanderson, SJ1
Beylot, M; Diraison, F; Pachiaudi, C1
Menon, S; Ragsdale, SW1
Pronk, JT; Van Dijken, JP; Yde Steensma, H1
Flikweert, MT; Pronk, JT; van Dijken, JP1
Abdel-aleem, S; el-Awady, MK; Karim, AM; Lowe, JE; Taylor, DA; Zarouk, WA1
Bielarczyk, H; Szutowicz, A; Tomaszewicz, M2
Bach, TJ; Disch, A; Hemmerlin, A; Rohmer, M1
Biswas, S; Dutta, DP; Misra, S; Ray, M; Ray, S1
Arigoni, D; Bacher, A; Eisenreich, W; Fuchs, G; Rieder, C; Strauss, G1
Bielarczyk, H; Jankowska, A; Szutowicz, A; Tomaszewicz, M1
Hochuli, M; Oesterhelt, D; Patzelt, H; Szyperski, T; Wüthrich, K1
Dominguez, LJ; Ofenstein, JP; Sarnaik, AP; Sowers, JR1
Christensen, B; Nielsen, J1
Baker, JC; Kasten, S; Peng, T; Roche, TE; Yan, X1
Comte, B; Poirier, M; Rosiers, CD; Vincent, G1
Furdui, C; Ragsdale, SW1
Heigenhauser, GJ; Jones, NL; Spriet, LL; St Amand, TA1
Christensen, B; Gombert, AK; Moreira dos Santos , M; Nielsen, J1
Bailey, JE; Cakar, ZP; Fiaux, J; Maaheimo, H; Sauer, U; Szyperski, T1
Evans, MK; Heigenhauser, GJ; Savasi, I; Spriet, LL1
Chabrière, E; Charon, MH; Fontecilla-Camps, JC; Guigliarelli, B; Hatchikian, EC; Vernède, X1
Bouchard, B; Brunengraber, H; Des Rosiers, C; Kelleher, JK; Poirier, M; Reszko, AE; Vincent, G1
Causey, TB; Ingram, LO; Shanmugam, KT; Underwood, SA; Yomano, LP; Zhou, S1
Brocks, C; Chatham, JC; Lloyd, S1
Anstrom, DM; Kallio, K; Remington, SJ1
GOEDDE, HW; HOLZER, H1
CETRULLO, C1
GRAY, CT; KORNBERG, HL1
COOPER, RA; KORNBERG, HL1
SAUER, F1
BENZIMAN, M; KLEIN, SM; SAGERS, RD1
COOPER, RA; ITIABA, K; KORNBERG, HL1
BERRY, MN1
Bouchard, B; Danialou, G; Des Rosiers, C; Khairallah, M; Labarthe, F; Petrof, BJ1
Brock, M; Buckel, W1
Bao, H; Kasten, SA; Roche, TE; Yan, X1
Surridge, C1
Goffman, F; Ohlrogge, JB; Schwender, J; Shachar-Hill, Y1
Crabb, BS; Foth, BJ; Handman, E; Hodder, AN; McFadden, GI; Stimmler, LM1
Kuzminov, A; Shi, IY; Stansbury, J1
Carvalho, RA; Castro, MM; Fonseca, CP; Geraldes, CF; Jeffrey, FM; Jones, JG; Montezinho, LP1
Kay, LE; Tugarinov, V1
von Glutz, G; Walter, P1
Habe, H; Inoue, K; Nojiri, H; Yamane, H1
Ohlrogge, JB; Schwender, J; Shachar-Hill, Y1
Cremades, N; Croxen, MA; Harman, WD; Hoffman, PS; Morash, MG; Sisson, G; Welch, K1
Englund, PT; Lee, SH; Paul, KS; Stephens, JL1
Fong, SS; Hua, Q; Joyce, AR; Palsson, BØ1
Coppi, MV; Lovley, DR; Orloff, A; Risso, C; Van Dien, SJ1
Hasegawa, T; Hashimoto, K; Kawasaki, H; Nakamatsu, T1
Berg, IA; Eisenreich, W; Eylert, E; Fuchs, G; Gallenberger, M; Huber, H; Jahn, U; Kockelkorn, D1
Barosa, C; Delgado, TC; Diogo, L; Garcia, P; Jones, JG1
Bennett, GN; Méndez, BS; Nikel, PI; San, KY; Zhu, J1
Doherty, TJ; Gurd, BJ; Heigenhauser, GJ; Kowalchuk, JM; LeBlanc, PJ; Paterson, DH; Peters, SJ1
Arai, H; Igarashi, Y; Ikeda, T; Ishii, M; Ohmori, D; Yamamoto, M1
Clomburg, JM; Gonzalez, R; Murarka, A1
Malloy, CR; Merritt, ME; Moreno, KX; Sabelhaus, SM; Sherry, AD1
Bielarczyk, H; Jankowska-Kulawy, A; Pawełczyk, T; Szutowicz, A; Wróblewska, M1
Blankenship, RE; Tang, KH1
Mayanagi, G; Takahashi, N; Washio, J1
Atherton, HJ; Clarke, K; Cochlin, LE; Dodd, MS; Lee, P; Radda, GK; Schroeder, MA; Tyler, DJ1
Bruchelt, G; Deubzer, B; Handgretinger, R; Krampen, L; Kuçi, Z; Niewisch, MR; Sautter, M; Wolburg, H1
Brekke, EM; Schousboe, A; Sonnewald, U; Waagepetersen, HS; Walls, AB1
Atteia, A; Martin, WF; Tielens, AG; van Lis, R1
Good, LB; Ma, Q; Malloy, CR; Marin-Valencia, I; Pascual, JM1
Bar-Even, A1
Atteia, A; Baffert, C; Couté, Y; Nitschke, W; van Lis, R1
Bouchard, B; Des Rosiers, C; Isern, N; Kajimoto, M; Ledee, DR; Olson, AK; Portman, MA; Priddy, CM1
Bowyer, P; Kaihovaara, P; Marttila, E; Rautemaa, R; Richardson, M; Salaspuro, M; Sanglard, D; Uittamo, J1
Allard, P; Alvarez, F; Gauthier, N; Kratz, L; Lépine, F; Mamer, OA; Mitchell, GA; Moser, AB; Robitaille, Y; Sweetman, L; Wang, SP; Wu, JW1
Bowie, JU; Eisenberg, D; Korman, TP; Li, D; Sahachartsiri, B; Vinokur, JM1
Chan, SH; Jensen, PR; Nørregaard, L; Solem, C1
Arjunan, P; Brukh, R; Calero, G; Chandrasekhar, K; Furey, W; Jordan, F; Kakalis, L; Kumaran, S; Nemeria, NS; Reynolds, S; Wang, J1
Chen, J; Du, G; Guo, H; Madzak, C; Zhou, J1
Basu, S; Beck, ME; Edmunds, LR; Goetzman, ES; Kang, A; Lu, J; Prochownik, EV; Scott, D; Sharma, L; Uppala, R; Vockley, J1
Alvarez, CE; Andreo, CS; Drincovich, MF; Golic, A; Hogenhout, SA; Mussi, MA; Saigo, M1
Burgess, SC; Kucejova, B; Malloy, CR; Merritt, ME; Purmal, C; Sherry, AD1
Calvaruso, MA; DeBerardinis, RJ; Hensley, CT; Jiang, L; Kim, J; Ko, B; Lumata, L; Merritt, ME; Mitsche, M; Rutter, J; Sudderth, J; Wasti, AT; Yang, C1
Hishiki, T; Honda, K; Hoshino, T; Kajimura, M; Kubo, A; Matsuura, T; Morikawa, T; Nagahata, Y; Nakanishi, T; Suematsu, M; Sugioka, T; Sugiura, Y; Takahashi, T; Takenouchi, T1
Furusawa, C; Hayakawa, K; Kajihata, S; Kanda, A; Matsuda, F; Shimizu, H; Yoshimi, M1
Berg, IA; Kronen, M; Sasikaran, J1
Adina-Zada, A; Attwood, PV; Choosangtong, K; Jitrapakdee, S; Sirithanakorn, C; Wallace, JC1
Cunha, RA; Jones, JG; Köfalvi, A; Lemos, C; Valente-Silva, P1
Amaral, AI; Hadera, MG; Kotter, MR; Sonnewald, U; Tavares, JM1
Debabov, VG; Gulevich, AY; Morzhakova, AA; Skorokhodova, AY1
Bielarczyk, H; Gul-Hinc, S; Höfling, C; Jankowska-Kulawy, A; Pawelczyk, T; Ronowska, A; Roßner, S; Schliebs, R; Szutowicz, A1
Alves, TC; Cline, GW; Kibbey, RG; Mason, G; Pongratz, RL; Sereda, S; Shirihai, O; Yarborough, O; Zhao, X1
Ito, T; Jong, CJ; Schaffer, SW; Shimada-Takaura, K; Takahashi, K1
Boer, VM; Daran, JM; Duine, HJ; Kötter, P; Kozak, BU; Luttik, MA; Niemeijer, MS; Pronk, JT; van Maris, AJ; van Rossum, HM1
Hwang, GW; Ishida, Y; Lee, JY; Naganuma, A; Takahashi, T1
Lisanti, MP; Martinez-Outschoorn, UE; Peiris-Pagés, M; Pestell, RG; Sotgia, F1
Chen, S; He, D; Sang, N; Tan, X; Yin, C1
Ariga, K; Hotta, K; Komatsu, H; Oka, K; Shindo, Y1
Antoniewicz, MR; Crown, SB; Kelleher, JK; Muoio, DM; Rouf, R1
Green, R; Karunakaran, R; Kruger, NJ; Masakapalli, SK; Poole, PS; Ratcliffe, RG; Terpolilli, JJ; Watmough, NJ; Webb, IU1
Alper, HS; Cordova, LT1
Broekaert, D; Buescher, JM; Christen, S; Davidson, SM; De Bock, K; Elia, I; Fendt, SM; Grünewald, TG; Lorendeau, D; Metzger, K; Orth, MF; Schmieder, R; Veys, K1
Gu, J; Hao, J; Jiang, B; Kim, CH; Shi, J; Wang, C; Wang, D; Wang, M; Zhou, J1
Dean, B; Scarr, E; Thomas, N; Udawela, M1
Ansari, IH; Burant, CF; El Azzouny, M; Jitrapakdee, S; Longacre, MJ; MacDonald, MJ; Phannasil, P; Rattanapornsompong, K1
Greenberg, ML; Joshi, AS; Li, G; Maddipati, KR; Raja, V1
Guo, J; Hezaveh, S; Jandt, U; Tatur, J; Zeng, AP1
Chin, YE; Cui, YG; Huang, C; Liang, JJ; Sun, WH; Tu, CE; Wang, Y; Xu, L; Xu, YS; Xu, YY; Yang, JH; Zhang, JM; Zhao, XJ; Zou, QC1
Alwine, JC; Sengupta, A; Vysochan, A; Weljie, AM; Yu, Y1
Hanai, T; Matsuda, F; Soma, Y; Yamaji, T1
Chang, JS; Hasunuma, T; Hirose, Y; Ho, SH; Kato, Y; Kondo, A; Minagawa, J; Misawa, N; Nakanishi, A; Yamasaki, H1
Camprubi, E; Jordan, SF; Lane, N; Vasiliadou, R1
Bridges, LC; Shaikh, SR; Westerhold, LE; Zeczycki, TN1
Durie, IA; Eiteman, MA; Niyas, AMM; Parimi, NS; Wu, X1
Della-Flora Nunes, G; Feltri, ML; Mueller, L; Patel, MS; Poitelon, Y; Silvestri, N; Wrabetz, L1
Alencastro, F; Bharathi, SS; Deshpande, R; Dolezal, JM; Duncan, AW; Goetzman, ES; Jackson, LE; Kulkarni, S; Lu, J; Patel, MS; Prochownik, EV; Ranganathan, S; Wang, H; Wendell, SG1
Stacpoole, PW1
Arnold, SA; Baxter, S; Eastham, G; Hall, SJ; Stephens, G; Webb, JP1
He, Q; Huang, F; Li, J; Shao, Y; Wang, T; Yao, W1
Brunengraber, H; Christopher, BA; McGarrah, RW; Muoio, D; Wang, Y; Wilson, KA; Zhang, GF1
Hu, X; Tam, KY; Zhang, W; Zhou, W1
Cluntun, AA; Cooper, DE; Garcia, BA; Kirsch, DG; Liu, J; Liu, X; Locasale, JW; Lopes, M; Lund, PJ; Reid, MA; Warmoes, MO; Wellen, KE; Zhao, S1
Chen, J; Du, G; Gu, Y; Li, J; Liu, L; Liu, Y; Lv, X; Rodrigo, LA1
Chen, M; Chi, H; Ding, Y; Guo, X; Li, Y; Ma, Y; Min, L; Wang, C; Wu, Y; Zhang, X; Zhao, Y1
Chen, D; Duan, Y; Li, J; Li, M; Xu, C; Zhou, M; Zhou, Z1
Chawla, A; Choi, BJ; Choi, YK; Ha, CM; Ham, HJ; Harris, RA; Hwang, D; Hyeon, DY; Jeon, JH; Kang, HJ; Kim, BG; Kim, DW; Kim, HE; Kim, JW; Kim, YH; Lee, CH; Lee, IK; Lee, J; Lee, JY; Lee, T; Min, BK; Oh, CJ; Park, KG; Park, S; Yoo, EK1
Altamirano, F; Gillette, TG; Malloy, CR; May, H; Merritt, ME; Schiattarella, GG; Turer, A1
Cho, S; Kim, H; Lee, J; Na, JG; Son, JH; Yang, J; Yeon, YJ1
Gao, X; Mamtawla, G; Wan, S; Wang, X; Yang, J; Zhang, L1
Cherono, S; Han, Y; Jiang, X; Liu, J; Ntini, C; Ogutu, C; Zhang, X; Zhao, L; Zheng, B1
Angus, DC; Bakalov, V; Chang, CH; Deshpande, R; Kaynar, AM; Le Moyec, L; Maloy, AL; Reyes-Uribe, L; Shapiro, SD; Wendell, SG1
Fujita, T; Hamuro, J; Hiramoto, N; Kinoshita, S; Mukai, A; Nakano, M; Numa, K; Sotozono, C; Tokuda, Y; Ueda, K; Ueno, M1
Reiter, RJ; Rosales-Corral, S; Sharma, R1
Johnsen, U; Kuprat, T; Ortjohann, M; Schönheit, P1
Kazak, L1
Berg, IA; Eisenreich, W; König, S; Mall, A; Pettinato, E; Steffens, L; Steiner, TM1
Bendahan, D; Chung, Y; Graham, J; Havel, PJ; Hurd, RE; Josan, S; Jue, T; Mayer, D; Park, JM; Spielman, DM1
Li, JC; Li, S; Li, Y; Mi, TY; Shen, XM; Wang, HL; Wang, LX; Xue, R; Yin, XL; Zhang, WW; Zhang, Y; Zhang, YZ1
Jakkamsetti, V; Ma, Q; Pascual, JM1
Li, Y; Ping, Q; Wang, S1
Lu, X; Peng, B; Yang, C; Yang, Y1

Reviews

12 review(s) available for acetyl coenzyme a and pyruvic acid

ArticleYear
A radical-chemical route to acetyl-CoA: the anaerobically induced pyruvate formate-lyase system of Escherichia coli.
    FEMS microbiology reviews, 1990, Volume: 6, Issue:4

    Topics: Acetyl Coenzyme A; Acetyltransferases; Anaerobiosis; Bacterial Proteins; Base Sequence; Consensus Sequence; Escherichia coli; Escherichia coli Proteins; Flavodoxin; Formates; Free Radicals; Gene Expression Regulation, Bacterial; Genes, Bacterial; Genes, Regulator; Iron-Sulfur Proteins; Molecular Sequence Data; Pyruvates; Pyruvic Acid; Transcription, Genetic

1990
Disorders of the pyruvate dehydrogenase complex.
    Journal of inherited metabolic disease, 1986, Volume: 9, Issue:2

    Topics: Acetyl Coenzyme A; Acetyltransferases; Acidosis; Brain; Carbon Dioxide; Child; Child, Preschool; Coenzyme A; Cranial Nerves; Dihydrolipoamide Dehydrogenase; Dihydrolipoyllysine-Residue Acetyltransferase; Facial Bones; Feedback; Humans; Lactates; Lactic Acid; Leigh Disease; Molecular Weight; Movement Disorders; NAD; Nervous System Diseases; Phosphoric Monoester Hydrolases; Pyruvate Decarboxylase; Pyruvate Dehydrogenase Complex; Pyruvate Dehydrogenase Complex Deficiency Disease; Pyruvates; Pyruvic Acid; Spectrophotometry

1986
Mechanism of coupled electron and group transfer in Escherichia coli pyruvate dehydrogenase.
    Annals of the New York Academy of Sciences, 1982, Volume: 378

    Topics: Acetyl Coenzyme A; Acetylation; Binding Sites; Chemical Phenomena; Chemistry; Coenzyme A; Electron Transport; Escherichia coli; Flavin-Adenine Dinucleotide; Molecular Weight; NAD; Oxidation-Reduction; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Spectrophotometry; Thiamine Pyrophosphate; Thioctic Acid

1982
The role of the cholinergic system in thiamin deficiency.
    Annals of the New York Academy of Sciences, 1982, Volume: 378

    Topics: Acetyl Coenzyme A; Acetylcholine; Aging; Animals; Arecoline; Atropine; Behavior, Animal; Brain; Diet; Electrophysiology; Ganglia, Sympathetic; Humans; Male; Oxythiamine; Parasympathetic Nervous System; Physostigmine; Pyrithiamine; Pyruvates; Pyruvic Acid; Rats; Synapses; Thiamine Deficiency; Tissue Distribution

1982
Pyruvate metabolism in Saccharomyces cerevisiae.
    Yeast (Chichester, England), 1996, Volume: 12, Issue:16

    Topics: Acetaldehyde; Acetyl Coenzyme A; Decarboxylation; Molecular Sequence Data; Oxaloacetates; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Saccharomyces cerevisiae

1996
Key role of acetyl-CoA in cytoplasm of nerve terminals in disturbances of acetylcholine metabolism in brain.
    Folia neuropathologica, 1997, Volume: 35, Issue:4

    Topics: 3-Hydroxybutyric Acid; Acetyl Coenzyme A; Acetylcholine; Aluminum; Animals; Brain; Brain Diseases; Cholinergic Fibers; Cytoplasm; Diabetes Mellitus; Energy Metabolism; Enzyme Inhibitors; Humans; Pyruvic Acid; Rats; Synaptosomes

1997
Metabolic network analysis. A powerful tool in metabolic engineering.
    Advances in biochemical engineering/biotechnology, 2000, Volume: 66

    Topics: Acetyl Coenzyme A; Algorithms; Biomass; Biomedical Technology; Citric Acid; Citric Acid Cycle; Glucose-6-Phosphate; Isocitrates; Lysine; Mannitol; Metabolism; Models, Biological; Oxaloacetic Acid; Propionates; Pyruvic Acid; Saccharomyces cerevisiae

2000
Anaerobic energy metabolism in unicellular photosynthetic eukaryotes.
    Biochimica et biophysica acta, 2013, Volume: 1827, Issue:2

    Topics: Acetyl Coenzyme A; Anaerobiosis; Energy Metabolism; Enzymes; Eukaryotic Cells; Fermentation; Microalgae; Phosphorylation; Photosynthesis; Pyruvic Acid

2013
Cancer metabolism: a therapeutic perspective.
    Nature reviews. Clinical oncology, 2017, Volume: 14, Issue:1

    Topics: Acetyl Coenzyme A; Adaptation, Physiological; Amino Acids; Antineoplastic Agents; Antioxidants; Autophagy; Blood Glucose; Energy Metabolism; Epigenomics; Fatty Acids; Genetic Heterogeneity; Glutamic Acid; Glutamine; Humans; Ketone Bodies; Lactic Acid; Lipids; Mitochondria; Mitochondrial Ribosomes; Neoplasms; Nucleic Acids; Oxidative Stress; Pyruvic Acid; TOR Serine-Threonine Kinases; Transcription Factors; Tumor Microenvironment

2017
Central metabolic nodes for diverse biochemical production.
    Current opinion in chemical biology, 2016, Volume: 35

    Topics: Acetyl Coenzyme A; Aspartic Acid; Bacteria; Citric Acid; Fungi; Pyruvic Acid; Tyrosine

2016
Therapeutic Targeting of the Pyruvate Dehydrogenase Complex/Pyruvate Dehydrogenase Kinase (PDC/PDK) Axis in Cancer.
    Journal of the National Cancer Institute, 2017, 11-01, Volume: 109, Issue:11

    Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Biomimetics; Citric Acid Cycle; Dichloroacetic Acid; Energy Metabolism; Glycolysis; Humans; Isoenzymes; Mitochondria; NAD; Neoplasms; Oxidative Phosphorylation; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvate Dehydrogenase Complex; Pyruvic Acid

2017
Anti-Warburg Effect of Melatonin: A Proposed Mechanism to Explain its Inhibition of Multiple Diseases.
    International journal of molecular sciences, 2021, Jan-14, Volume: 22, Issue:2

    Topics: Acetyl Coenzyme A; Animals; Glucose; Glycolysis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Melatonin; Mitochondria; Neoplasms; Pentose Phosphate Pathway; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Warburg Effect, Oncologic

2021

Trials

2 trial(s) available for acetyl coenzyme a and pyruvic acid

ArticleYear
Pyruvate overrides inhibition of PDH during exercise after a low-carbohydrate diet.
    American journal of physiology. Endocrinology and metabolism, 2000, Volume: 279, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acetyl Coenzyme A; Acetylcarnitine; Adult; Blood Glucose; Dietary Carbohydrates; Exercise Test; Fatty Acids, Nonesterified; Food, Formulated; Glycerol; Glycerophosphates; Glycogen; Humans; Insulin; Lactic Acid; Male; Muscle, Skeletal; Physical Exertion; Protein Kinases; Protein Serine-Threonine Kinases; Pulmonary Gas Exchange; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Reference Values

2000
Effects of acetate infusion and hyperoxia on muscle substrate phosphorylation after onset of moderate exercise.
    American journal of physiology. Endocrinology and metabolism, 2001, Volume: 281, Issue:6

    Topics: Acetates; Acetyl Coenzyme A; Acetylcarnitine; Adenosine Diphosphate; Adenosine Monophosphate; Adult; Exercise; Exercise Test; Glycolysis; Humans; Hyperoxia; Lactic Acid; Male; Muscle, Skeletal; Oxidative Phosphorylation; Oxygen Consumption; Phosphocreatine; Pyruvate Dehydrogenase Complex; Pyruvic Acid

2001

Other Studies

174 other study(ies) available for acetyl coenzyme a and pyruvic acid

ArticleYear
Mechanism of L-serine oxidation in Entamoeba histolytica.
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1979, Volume: 62, Issue:3

    Topics: Acetyl Coenzyme A; Ammonia; Animals; Entamoeba histolytica; L-Serine Dehydratase; Oxidation-Reduction; Oxygen Consumption; Pyruvate Oxidase; Pyruvates; Pyruvic Acid; Serine

1979
Determination of flux through different metabolite pathways in Saccharomyces cerevisiae by 1H-NMR and 13C-NMR spectroscopy.
    European journal of biochemistry, 1991, Nov-01, Volume: 201, Issue:3

    Topics: Acetyl Coenzyme A; Carbon Isotopes; Citric Acid Cycle; Ethanol; Glucose; Glutamates; Glutamic Acid; Magnetic Resonance Spectroscopy; Models, Biological; Protons; Pyruvates; Pyruvic Acid; Saccharomyces cerevisiae

1991
Pyruvate carboxylation prevents the decline in contractile function of rat hearts oxidizing acetoacetate.
    The American journal of physiology, 1991, Volume: 261, Issue:6 Pt 2

    Topics: Acetoacetates; Acetyl Coenzyme A; Animals; Coenzyme A; Malate Dehydrogenase; Male; Myocardial Contraction; Myocardium; NADP; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Tartronates

1991
Pyruvate carboxylase catalysis of phosphate transfer between carbamoyl phosphate and ADP.
    The Biochemical journal, 1991, Jan-15, Volume: 273(Pt 2)

    Topics: Acetyl Coenzyme A; Adenosine Diphosphate; Animals; Binding Sites; Biotin; Carbamyl Phosphate; Chickens; Hydrogen-Ion Concentration; Kinetics; Liver; Magnesium; Oxaloacetates; Oxamic Acid; Phosphorylation; Pyruvate Carboxylase; Pyruvates; Pyruvic Acid; Substrate Specificity

1991
Muscle carnitine metabolism during incremental dynamic exercise in humans.
    Acta physiologica Scandinavica, 1990, Volume: 138, Issue:3

    Topics: Acetyl Coenzyme A; Acetylcarnitine; Adult; Carnitine; Exercise; Humans; Lactates; Lactic Acid; Male; Muscles; Oxygen Consumption; Pyruvates; Pyruvic Acid

1990
Mechanisms of substrate preference for oxidative metabolism during early myocardial reperfusion.
    The American journal of physiology, 1990, Volume: 259, Issue:2 Pt 2

    Topics: Acetyl Coenzyme A; Acetylcarnitine; Animals; Coronary Disease; Fatty Acids; Glycine; Myocardial Reperfusion; Myocardium; Oxidation-Reduction; Oxygen Consumption; Pyruvates; Pyruvic Acid; Swine

1990
Evidence for oxidative thiolytic cleavage of acetoin in Pelobacter carbinolicus analogous to aerobic oxidative decarboxylation of pyruvate.
    FEMS microbiology letters, 1989, Jul-01, Volume: 51, Issue:1

    Topics: Acetoin; Acetyl Coenzyme A; Acetyltransferases; Bacteria, Anaerobic; Butanones; Chromatography; Decarboxylation; Dihydrolipoamide Dehydrogenase; Dihydrolipoyllysine-Residue Acetyltransferase; Electrophoresis, Polyacrylamide Gel; Ethylene Glycol; Ethylene Glycols; Metronidazole; Models, Chemical; Oxidation-Reduction; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid

1989
Pyruvate dehydrogenase and the path of lactate degradation in Desulfovibrio vulgaris Miyazaki F.
    Journal of biochemistry, 1986, Volume: 100, Issue:2

    Topics: Acetyl Coenzyme A; Cytochrome c Group; Desulfovibrio; Flavin Mononucleotide; Hydrogen-Ion Concentration; Ketone Oxidoreductases; Kinetics; Lactates; Lactic Acid; Molecular Weight; Pyruvate Dehydrogenase Complex; Pyruvate Synthase; Pyruvates; Pyruvic Acid; Substrate Specificity; Temperature

1986
Biochemical effects of acute stress on energy metabolism in liver damaged rats.
    Physiology & behavior, 1987, Volume: 40, Issue:1

    Topics: Acetyl Coenzyme A; Animals; Chemical and Drug Induced Liver Injury; Cyclic AMP; Cyclic GMP; Energy Metabolism; Galactosamine; Ketone Bodies; Lactates; Lactic Acid; Liver Diseases; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Stress, Physiological

1987
Pathways of acetone's metabolism in the rat.
    The Journal of biological chemistry, 1986, Mar-25, Volume: 261, Issue:9

    Topics: Acetone; Acetyl Coenzyme A; Animals; Diabetes Mellitus, Experimental; Diabetic Ketoacidosis; Female; Hydroxybutyrates; Lactates; Lactic Acid; Liver; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains

1986
Purification and characterization of pyruvate:NADP+ oxidoreductase in Euglena gracilis.
    The Journal of biological chemistry, 1987, Jul-05, Volume: 262, Issue:19

    Topics: Acetyl Coenzyme A; Animals; Carbon Dioxide; Coenzyme A; Euglena gracilis; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Ketone Oxidoreductases; Molecular Weight; NAD; NADP; Pyruvates; Pyruvic Acid

1987
Stimulation by D-glucose of mitochondrial oxidative events in islet cells.
    The Biochemical journal, 1987, Aug-15, Volume: 246, Issue:1

    Topics: Acetyl Coenzyme A; Amino Acids; Animals; Cell Line; Glucose; Islets of Langerhans; Mitochondria; NAD; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Stimulation, Chemical

1987
Net citrate production by isolated prostate epithelial cells.
    Enzyme, 1988, Volume: 39, Issue:3

    Topics: Acetyl Coenzyme A; Animals; Aspartate Aminotransferases; Aspartic Acid; Citrates; Citric Acid; Epithelium; Glutamate Dehydrogenase; Ketoglutaric Acids; Male; Mitochondria; Oxaloacetates; Prostate; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains

1988
Carnitine stimulation of pyruvate dehydrogenase complex (PDHC) in isolated human skeletal muscle mitochondria.
    Muscle & nerve, 1988, Volume: 11, Issue:7

    Topics: Acetyl Coenzyme A; Acetylcarnitine; Carnitine; Carnitine O-Acetyltransferase; Humans; Mitochondria, Muscle; Oxidation-Reduction; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Stimulation, Chemical

1988
Stoichiometric traps in the tricarboxylic acid cycle. I. Self-inhibition and triggering phenomena.
    Biochemistry international, 1987, Volume: 14, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acetyl Coenzyme A; Animals; Citric Acid Cycle; Columbidae; Feedback; Hydroxybutyrates; Ketoglutaric Acids; Ketone Bodies; Mitochondria, Heart; Oxidation-Reduction; Oxygen Consumption; Pyruvates; Pyruvic Acid; Rats; Uncoupling Agents

1987
2-Oxoglutarate dehydrogenase and pyruvate dehydrogenase activities in plant mitochondria: interaction via a common coenzyme a pool.
    Archives of biochemistry and biophysics, 1987, Aug-15, Volume: 257, Issue:1

    Topics: Acetyl Coenzyme A; Coenzyme A; Ketoglutarate Dehydrogenase Complex; Ketoglutaric Acids; Ketone Oxidoreductases; Mitochondria; NAD; Oxaloacetates; Oxidation-Reduction; Oxygen Consumption; Plants; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid

1987
Determination of Krebs cycle metabolic carbon exchange in vivo and its use to estimate the individual contributions of gluconeogenesis and glycogenolysis to overall glucose output in man.
    The Journal of clinical investigation, 1987, Volume: 80, Issue:5

    Topics: 3-Hydroxybutyric Acid; Acetates; Acetic Acid; Acetyl Coenzyme A; Adult; Blood Glucose; Carbon; Carbon Radioisotopes; Citric Acid Cycle; Fasting; Female; Gluconeogenesis; Glucose; Glycogen; Humans; Hydroxybutyrates; Male; Middle Aged; Mitochondria; Phosphoenolpyruvate; Pyruvates; Pyruvic Acid; Tritium

1987
Avidin as a probe of the conformational changes induced in pyruvate carboxylase by acetyl-CoA and pyruvate.
    FEBS letters, 1986, Jul-28, Volume: 203, Issue:2

    Topics: Acetyl Coenzyme A; Animals; Avidin; Chickens; Liver; Ovalbumin; Protein Conformation; Pyruvate Carboxylase; Pyruvates; Pyruvic Acid; Sheep

1986
Pyruvate carboxylase: mechanisms of the partial reactions.
    Annals of the New York Academy of Sciences, 1985, Volume: 447

    Topics: Acetyl Coenzyme A; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Binding Sites; Biotin; Kinetics; Magnesium; Models, Chemical; Pyruvate Carboxylase; Pyruvates; Pyruvic Acid; Sheep

1985
Effect of insulin on ketogenesis and fatty acid synthesis in rat hepatocytes incubated with dichloroacetate.
    Biochimica et biophysica acta, 1985, Mar-21, Volume: 844, Issue:3

    Topics: Acetates; Acetyl Coenzyme A; Animals; Carbon Dioxide; Citrates; Citric Acid; Dichloroacetic Acid; Enzyme Activation; Fatty Acids; Female; Insulin; Ketone Bodies; Liver; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains

1985
The physiological role of oxygen-sensitive pyruvate dehydrogenase in mitochondrial fatty acid synthesis in Euglena gracilis.
    Archives of biochemistry and biophysics, 1985, Volume: 237, Issue:2

    Topics: Acetyl Coenzyme A; Euglena gracilis; Fatty Acids; Mitochondria; Oxygen; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid

1985
Halothane-induced alterations of glucose and pyruvate metabolism in rat cerebra synaptosomes.
    Journal of neurochemistry, 1985, Volume: 44, Issue:6

    Topics: Acetyl Coenzyme A; Acetylcholine; Animals; ATP Citrate (pro-S)-Lyase; Brain; Carbon Dioxide; Glucose; Halothane; In Vitro Techniques; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Synaptosomes

1985
Regulation of mitochondrial pyruvate carboxylation in isolated hepatocytes by acute insulin treatment.
    The Biochemical journal, 1983, Aug-15, Volume: 214, Issue:2

    Topics: Acetyl Coenzyme A; Adenine Nucleotides; Animals; Cyclic AMP; Epinephrine; Filipin; Glucagon; Gluconeogenesis; In Vitro Techniques; Insulin; Liver; Male; Mitochondria, Liver; Pyruvate Carboxylase; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains

1983
The stimulus-secretion coupling of amino acid-induced insulin release: metabolism of L-asparagine in pancreatic islets.
    Archives of biochemistry and biophysics, 1984, Feb-15, Volume: 229, Issue:1

    Topics: Acetyl Coenzyme A; Animals; Asparaginase; Asparagine; Aspartic Acid; Cytosol; Fatty Acids; Islets of Langerhans; Kinetics; Mitochondria; NAD; NADP; Oxaloacetates; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats

1984
The role of threonine in the metabolism of acetyl coenzyme a by Trypanosoma brucei brucei.
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1983, Volume: 74, Issue:2

    Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Animals; Carbon Dioxide; Cells, Cultured; Fatty Acids; Glucose; Glycolysis; Oxygen Consumption; Pyruvates; Pyruvic Acid; Threonine; Trypanosoma brucei brucei

1983
Intermediary carbon metabolism of Azospirillum brasilense.
    Journal of bacteriology, 1984, Volume: 158, Issue:1

    Topics: Acetates; Acetyl Coenzyme A; Bacteria; Carbon Dioxide; Cell Wall; Citric Acid Cycle; Culture Media; Gluconeogenesis; Glucose; Kinetics; Lipids; Oxygen Consumption; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Succinates; Succinic Acid

1984
Effects of fenfluramine on hepatic intermediary metabolism.
    Biochemical pharmacology, 1983, Nov-15, Volume: 32, Issue:22

    Topics: Acetyl Coenzyme A; Alanine; Animals; Fatty Acids; Fenfluramine; Gluconeogenesis; Glycolysis; Ketone Bodies; Lactates; Lactic Acid; Liver; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains

1983
Pathways of acetyl CoA production for lipogenesis from acetoacetate, beta-hydroxybutyrate, pyruvate and glucose in neonatal rat lung.
    Lipids, 1984, Volume: 19, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetyl Coenzyme A; Animals; Animals, Newborn; Citrates; Fatty Acids; Glucose; Glycerides; Hydroxybutyrates; Lipids; Lung; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains

1984
The regulation of the pyruvate dehydrogenase complex in the perfused rat liver: a role for the mitochondrial monocarboxylate translocator.
    Archives of biochemistry and biophysics, 1982, Volume: 213, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acetyl Coenzyme A; Animals; Carbon Dioxide; Carrier Proteins; Hydroxybutyrates; Liver; Male; Monocarboxylic Acid Transporters; NAD; Perfusion; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains

1982
The role of lipoic acid residues in the pyruvate dehydrogenase multienzyme complex of Escherichia coli.
    The Biochemical journal, 1981, Dec-01, Volume: 199, Issue:3

    Topics: Acetyl Coenzyme A; Acetylation; Escherichia coli; Ethylmaleimide; NAD; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Thioctic Acid

1981
Mutants of Escherichia coli K12 with defects in anaerobic pyruvate metabolism.
    Journal of general microbiology, 1981, Volume: 124, Issue:1

    Topics: Acetates; Acetyl Coenzyme A; Anaerobiosis; Escherichia coli; Mutation; Nitrates; Nitrites; Oxidation-Reduction; Pyruvates; Pyruvic Acid

1981
Citrate synthesis in intact rat-liver mitochondria is irreversible.
    European journal of biochemistry, 1982, Volume: 122, Issue:2

    Topics: Acetyl Coenzyme A; Animals; Citrates; Citric Acid; Female; Malates; Mitochondria, Liver; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains

1982
The contribution of citrate to the synthesis of acetyl units in synaptosomes of developing rat brain.
    Journal of neurochemistry, 1982, Volume: 38, Issue:5

    Topics: Acetyl Coenzyme A; Animals; ATP Citrate (pro-S)-Lyase; Brain; Choline O-Acetyltransferase; Citrate (si)-Synthase; Citrates; Citric Acid; Female; Malates; Male; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Rats; Synaptosomes

1982
Fumarate reduction and product formation by the Reiter strain of Treponema phagedenis.
    Journal of bacteriology, 1982, Volume: 152, Issue:3

    Topics: Acetates; Acetyl Coenzyme A; Butyrates; Culture Media; Electron Transport; Ethanol; Ferredoxins; Flavin-Adenine Dinucleotide; Fumarates; Glucose; NAD; NADP; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Succinates; Treponema

1982
Theoretical study on preference of metabolic fuels in heart muscle cells.
    Acta biologica et medica Germanica, 1981, Volume: 40, Issue:3

    Topics: Acetates; Acetyl Coenzyme A; Adenosine Triphosphate; Energy Metabolism; Kinetics; Models, Biological; Myocardium; NAD; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid

1981
The origin of chloroplastic acetyl coenzyme A.
    Archives of biochemistry and biophysics, 1981, Volume: 212, Issue:2

    Topics: Acetyl Coenzyme A; Carbon Radioisotopes; Chloroplasts; Kinetics; Mitochondria; Organoids; Plants; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid

1981
Metabolism of [3-13C]pyruvate and [3-13C]propionate in normal and ischaemic rat heart in vivo: 1H- and 13C-NMR studies.
    The Biochemical journal, 1995, Nov-15, Volume: 312 ( Pt 1)

    Topics: Acetyl Coenzyme A; Alanine; Animals; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Myocardial Ischemia; Myocardium; Propionates; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar

1995
Kinetics of nucleotide binding to pyruvate carboxylase.
    Biochemistry, 1995, Sep-19, Volume: 34, Issue:37

    Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Animals; Bicarbonates; Binding Sites; Binding, Competitive; Chickens; Fluorescent Dyes; Formycins; In Vitro Techniques; Kinetics; Liver; Magnesium; Models, Biological; Pyruvate Carboxylase; Pyruvates; Pyruvic Acid; Ribonucleotides; Spectrometry, Fluorescence

1995
Acetylcholine synthesis in nerve terminals of diabetic rats.
    Neuroreport, 1994, Dec-20, Volume: 5, Issue:18

    Topics: 3-Hydroxybutyric Acid; Acetyl Coenzyme A; Acetylcholine; Animals; Brain; Diabetes Mellitus, Experimental; Hydroxybutyrates; Insulin; Male; Nerve Endings; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Synaptosomes

1994
Cytokines inhibit fatty acid oxidation in isolated rat hepatocytes: synergy among TNF, IL-6, and IL-1.
    Shock (Augusta, Ga.), 1994, Volume: 1, Issue:2

    Topics: Acetyl Coenzyme A; Alanine; Animals; Cells, Cultured; Citric Acid Cycle; Depression, Chemical; Drug Synergism; Energy Metabolism; Fatty Acids; Interleukin-1; Interleukin-6; Ketone Bodies; Liver; Malonyl Coenzyme A; Models, Biological; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha

1994
Biosynthesis of armentomycin: a chlorinated nonprotein amino acid.
    The Journal of antibiotics, 1995, Volume: 48, Issue:4

    Topics: Acetyl Coenzyme A; Aminobutyrates; Anti-Bacterial Agents; Chlorine; Glycerol; Magnetic Resonance Spectroscopy; Phosphoenolpyruvate; Pyruvates; Pyruvic Acid; Streptomyces

1995
Isotopomer studies of gluconeogenesis and the Krebs cycle with 13C-labeled lactate.
    The Journal of biological chemistry, 1993, Dec-05, Volume: 268, Issue:34

    Topics: Acetyl Coenzyme A; Alanine; Animals; Blood Glucose; Carbon Dioxide; Carbon Isotopes; Citric Acid Cycle; Gas Chromatography-Mass Spectrometry; Gluconeogenesis; Glucose; Glutamates; Glutamic Acid; Glutamine; Isotope Labeling; Lactates; Lactic Acid; Liver; Male; Oxaloacetates; Phosphoenolpyruvate; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley

1993
Ligand binding on to maize (Zea mays) malate synthase: a structural study.
    The Biochemical journal, 1994, Oct-15, Volume: 303 ( Pt 2)

    Topics: Acetyl Coenzyme A; Binding Sites; Circular Dichroism; Fluoroacetates; Glycolates; Glyoxylates; Kinetics; Ligands; Magnesium Chloride; Malate Synthase; Molecular Weight; Protein Conformation; Pyruvates; Pyruvic Acid; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Substrate Specificity; Trypsin; Zea mays

1994
Importance of the modulation of glycolysis in the control of lactate metabolism by fatty acids in isolated hepatocytes from fed rats.
    Archives of biochemistry and biophysics, 1994, Volume: 309, Issue:2

    Topics: Acetyl Coenzyme A; Animals; Butyrates; Butyric Acid; Caprylates; Citrates; Citric Acid; Fatty Acids; Fructosediphosphates; Glycolysis; Ketone Bodies; Lactates; Lactic Acid; Liver; Male; Oleic Acid; Oleic Acids; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar

1994
Alanine as a lipogenic precursor in isolated hepatocytes from obese Zucker rats.
    Cellular and molecular biology (Noisy-le-Grand, France), 1993, Volume: 39, Issue:6

    Topics: Acetyl Coenzyme A; Alanine; Alanine Transaminase; Animals; Cells, Cultured; Citrates; Coumaric Acids; Fatty Acids; Glucose; Lactates; Lactic Acid; Leucine; Lipids; Liver; Liver Glycogen; Male; Mitochondria, Liver; Obesity; Pyruvates; Pyruvic Acid; Rats; Rats, Zucker

1993
Pyruvate is a lipid precursor for rat lymphocytes in culture: evidence for a lipid exporting capacity.
    Biochemistry and molecular biology international, 1993, Volume: 30, Issue:4

    Topics: Acetates; Acetyl Coenzyme A; Animals; Cells, Cultured; Concanavalin A; Culture Media; HeLa Cells; Humans; Lipid Metabolism; Lipids; Lymphocytes; Macrophages, Peritoneal; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar

1993
Stoichiometry, organisation and catalytic function of protein X of the pyruvate dehydrogenase complex from bovine heart.
    European journal of biochemistry, 1996, Feb-15, Volume: 236, Issue:1

    Topics: Acetyl Coenzyme A; Acetylation; Animals; Cattle; Collagenases; Cross-Linking Reagents; Myocardium; NAD; Peptides; Protein Conformation; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Thioctic Acid

1996
In vivo measurement of plasma cholesterol and fatty acid synthesis with deuterated water: determination of the average number of deuterium atoms incorporated.
    Metabolism: clinical and experimental, 1996, Volume: 45, Issue:7

    Topics: Acetyl Coenzyme A; Animals; Blood Chemical Analysis; Blood Glucose; Cholesterol; Deuterium; Deuterium Oxide; Fatty Acids; Gas Chromatography-Mass Spectrometry; Lactates; Lactic Acid; Liver; Male; Palmitates; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Triglycerides

1996
Unleashing hydrogenase activity in carbon monoxide dehydrogenase/acetyl-CoA synthase and pyruvate:ferredoxin oxidoreductase.
    Biochemistry, 1996, Dec-10, Volume: 35, Issue:49

    Topics: Acetyl Coenzyme A; Aldehyde Oxidoreductases; Binding Sites; Carbon Monoxide; Clostridium; Electron Transport; Hydrogen; Hydrogenase; Ketone Oxidoreductases; Kinetics; Multienzyme Complexes; Oxidation-Reduction; Paraquat; Potassium Cyanide; Protons; Pyruvate Synthase; Pyruvic Acid; Thiamine Pyrophosphate

1996
Metabolic responses of pyruvate decarboxylase-negative Saccharomyces cerevisiae to glucose excess.
    Applied and environmental microbiology, 1997, Volume: 63, Issue:9

    Topics: Acetyl Coenzyme A; Citric Acid Cycle; Glucose; Glycolysis; Kinetics; NAD; Oxygen Consumption; Phosphorylation; Pyruvate Decarboxylase; Pyruvic Acid; Saccharomyces cerevisiae

1997
Reduced effects of L-carnitine on glucose and fatty acid metabolism in myocytes isolated from diabetic rats.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1997, Volume: 29, Issue:9

    Topics: Acetyl Coenzyme A; Acetylcarnitine; Animals; Carbon Radioisotopes; Carnitine; Citric Acid Cycle; Diabetes Mellitus, Experimental; Fatty Acids; Glucose; Heart; Kinetics; Male; Myocardium; Oxidation-Reduction; Palmitic Acid; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Rats; Rats, Sprague-Dawley

1997
Effect of aluminum on acetyl-CoA and acetylcholine metabolism in nerve terminals.
    Journal of neurochemistry, 1998, Volume: 70, Issue:3

    Topics: Acetyl Coenzyme A; Acetylcholine; Aluminum; Animals; Calcium Channel Blockers; Cell Compartmentation; Citric Acid; Male; Mitochondria; Nerve Endings; Phosphates; Potassium; Pyruvic Acid; Rats; Rats, Wistar; Synaptosomes; Verapamil

1998
Mevalonate-derived isopentenyl diphosphate is the biosynthetic precursor of ubiquinone prenyl side chain in tobacco BY-2 cells.
    The Biochemical journal, 1998, Apr-15, Volume: 331 ( Pt 2)

    Topics: Acetyl Coenzyme A; Carbon Isotopes; Cell Line; Coenzymes; Glucose; Glyceraldehyde 3-Phosphate; Hemiterpenes; Mevalonic Acid; Mitochondria; Nicotiana; Organophosphorus Compounds; Plants, Toxic; Plastoquinone; Polyisoprenyl Phosphates; Pyruvic Acid; Sterols; Ubiquinone

1998
Is absence of pyruvate dehydrogenase complex in mitochondria a possible explanation of significant aerobic glycolysis by normal human leukocytes?
    FEBS letters, 1998, Apr-03, Volume: 425, Issue:3

    Topics: Acetyl Coenzyme A; Acetylation; Aniline Compounds; Arylamine N-Acetyltransferase; Glycolysis; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukocytes; Mitochondria; Oxygen Consumption; Pyruvate Dehydrogenase Complex; Pyruvic Acid

1998
Biosynthesis of the diterpene verrucosan-2beta-ol in the phototrophic eubacterium Chloroflexus aurantiacus. A retrobiosynthetic NMR study.
    The Journal of biological chemistry, 1998, Jul-17, Volume: 273, Issue:29

    Topics: Acetyl Coenzyme A; Chlorobi; Diterpenes; Glyceraldehyde 3-Phosphate; Magnetic Resonance Spectroscopy; Mevalonic Acid; Models, Chemical; Pyruvic Acid; Xylulose

1998
Pathways of beta-hydroxybutyrate contribution to metabolism of acetyl-CoA and acetylcholine in rat brain nerve terminals.
    Folia neuropathologica, 1997, Volume: 35, Issue:4

    Topics: 3-Hydroxybutyric Acid; Acetyl Coenzyme A; Acetylcholine; Animals; Brain; Calcium; Cholinergic Fibers; Cytoplasm; Male; Mitochondria; Pyruvic Acid; Rats; Rats, Wistar; Synaptosomes

1997
Amino acid biosynthesis in the halophilic archaeon Haloarcula hispanica.
    Journal of bacteriology, 1999, Volume: 181, Issue:10

    Topics: Acetyl Coenzyme A; Amino Acid Oxidoreductases; Amino Acids; Bacteria; Carbon; Diaminopimelic Acid; Eukaryotic Cells; Evolution, Molecular; Glycerol; Haloarcula; Isoleucine; Lysine; Magnetic Resonance Spectroscopy; Models, Chemical; Oxaloacetic Acid; Pyruvic Acid; Threonine; Tyrosine

1999
Effects of insulin and metformin on glucose metabolism in rat vascular smooth muscle.
    Metabolism: clinical and experimental, 1999, Volume: 48, Issue:11

    Topics: Acetyl Coenzyme A; Animals; Glucose; Hypoglycemic Agents; Insulin; Lactic Acid; Male; Metformin; Mitochondria, Muscle; Muscle, Smooth, Vascular; Oxidation-Reduction; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Rats; Rats, Sprague-Dawley

1999
Marked differences between two isoforms of human pyruvate dehydrogenase kinase.
    The Journal of biological chemistry, 2000, May-26, Volume: 275, Issue:21

    Topics: Acetyl Coenzyme A; Acetylation; Acetyltransferases; Binding Sites; Buffers; Dichloroacetic Acid; Dihydrolipoyllysine-Residue Acetyltransferase; Enzyme Activation; Enzyme Inhibitors; Humans; Isoenzymes; Kinetics; NAD; Protein Binding; Protein Kinases; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Recombinant Proteins

2000
Citrate release by perfused rat hearts: a window on mitochondrial cataplerosis.
    American journal of physiology. Endocrinology and metabolism, 2000, Volume: 278, Issue:5

    Topics: Acetyl Coenzyme A; Animals; Caprylates; Citric Acid; Energy Metabolism; Gas Chromatography-Mass Spectrometry; Glucose; In Vitro Techniques; Indicator Dilution Techniques; Insulin; L-Lactate Dehydrogenase; Lactic Acid; Male; Mitochondria, Heart; Myocardium; Oxaloacetic Acid; Pyruvic Acid; Rats; Rats, Sprague-Dawley

2000
The role of pyruvate ferredoxin oxidoreductase in pyruvate synthesis during autotrophic growth by the Wood-Ljungdahl pathway.
    The Journal of biological chemistry, 2000, Sep-15, Volume: 275, Issue:37

    Topics: Acetyl Coenzyme A; Carbon Dioxide; Clostridium; Ferredoxins; Ketone Oxidoreductases; Pyruvate Synthase; Pyruvic Acid

2000
Network identification and flux quantification in the central metabolism of Saccharomyces cerevisiae under different conditions of glucose repression.
    Journal of bacteriology, 2001, Volume: 183, Issue:4

    Topics: Acetyl Coenzyme A; Cell Compartmentation; Citric Acid Cycle; DNA-Binding Proteins; Enzyme Repression; Gene Expression Regulation, Fungal; Glucose; Glycine; Malate Dehydrogenase; Models, Theoretical; Mutation; Pentose Phosphate Pathway; Pyruvic Acid; Repressor Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins

2001
Central carbon metabolism of Saccharomyces cerevisiae explored by biosynthetic fractional (13)C labeling of common amino acids.
    European journal of biochemistry, 2001, Volume: 268, Issue:8

    Topics: Acetyl Coenzyme A; Alanine Transaminase; Amino Acids; Carbon; Citric Acid Cycle; Cytosol; Databases, Factual; Escherichia coli; Glucose; Glycine; Glycolysis; Glyoxylates; Magnetic Resonance Spectroscopy; Mitochondria; Models, Chemical; Models, Theoretical; Oxaloacetic Acid; Pyruvates; Pyruvic Acid; Saccharomyces cerevisiae; Software

2001
Crystal structure of the free radical intermediate of pyruvate:ferredoxin oxidoreductase.
    Science (New York, N.Y.), 2001, Dec-21, Volume: 294, Issue:5551

    Topics: Acetyl Coenzyme A; Anaerobiosis; Binding Sites; Carbon Dioxide; Catalysis; Chemical Phenomena; Chemistry, Physical; Coenzymes; Crystallization; Crystallography, X-Ray; Desulfovibrio; Dimerization; Electron Spin Resonance Spectroscopy; Free Radicals; Ketone Oxidoreductases; Molecular Conformation; Molecular Structure; Oxidation-Reduction; Protein Conformation; Pyruvate Synthase; Pyruvic Acid; Thiamine Pyrophosphate

2001
Probing the link between citrate and malonyl-CoA in perfused rat hearts.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:4

    Topics: Acetyl Coenzyme A; Animals; ATP Citrate (pro-S)-Lyase; Carbon Isotopes; Citrates; Citric Acid; Citric Acid Cycle; Gas Chromatography-Mass Spectrometry; In Vitro Techniques; Male; Malonyl Coenzyme A; Myocardial Contraction; Myocardium; Perfusion; Pyruvic Acid; Rats; Rats, Sprague-Dawley

2002
Genetic changes to optimize carbon partitioning between ethanol and biosynthesis in ethanologenic Escherichia coli.
    Applied and environmental microbiology, 2002, Volume: 68, Issue:12

    Topics: Acetic Acid; Acetyl Coenzyme A; Adenosine Triphosphate; Carbohydrate Metabolism; Carbon; Escherichia coli; Ethanol; Pyruvic Acid

2002
Differential modulation of glucose, lactate, and pyruvate oxidation by insulin and dichloroacetate in the rat heart.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 285, Issue:1

    Topics: Acetyl Coenzyme A; Alanine; Animals; Buffers; Citric Acid Cycle; Dichloroacetic Acid; Energy Metabolism; Glucose; Heart; Heart Function Tests; Heart Rate; Hypoglycemic Agents; In Vitro Techniques; Insulin; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Myocardium; Oxidation-Reduction; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Ventricular Function, Left

2003
Structure of the Escherichia coli malate synthase G:pyruvate:acetyl-coenzyme A abortive ternary complex at 1.95 A resolution.
    Protein science : a publication of the Protein Society, 2003, Volume: 12, Issue:9

    Topics: Acetyl Coenzyme A; Arginine; Aspartic Acid; Binding Sites; Candida albicans; Crystallography, X-Ray; Cysteine; Escherichia coli; Kinetics; Malate Synthase; Models, Chemical; Models, Molecular; Mutagenesis; Mycobacterium tuberculosis; Oxidation-Reduction; Protein Binding; Protein Conformation; Protein Isoforms; Pyruvic Acid; Sulfenic Acids; X-Rays

2003
[Two ways from pyruvate to acetyl-coenzyme A in yeast].
    Biochemische Zeitschrift, 1957, Volume: 329, Issue:3

    Topics: Acetyl Coenzyme A; Coenzymes; Pyruvates; Pyruvic Acid; Saccharomyces cerevisiae; Yeast, Dried; Yeasts

1957
[Mechanism of action of barbiturates. IV. Effect of barbiturates on the biosynthesis of acetyl-coenzyme A in an enzymatic system oxidizing pyruvate].
    Minerva anestesiologica, 1958, Volume: 24, Issue:1

    Topics: Acetyl Coenzyme A; Barbiturates; Coenzymes; Pyruvates; Pyruvic Acid

1958
Enzymic formation of citramalate from acetyl-coenzyme A and pyruvate in Pseudomonas ovalis Chester, catalysed by "pyruvate transacetase".
    Biochimica et biophysica acta, 1960, Aug-12, Volume: 42

    Topics: Acetyl Coenzyme A; Biochemical Phenomena; Coenzymes; Malates; Pseudomonas; Pseudomonas putida; Pyruvates; Pyruvic Acid

1960
Formation of pyruvate and acetyl-coenzyme A from itaconyl-coenzyme A by Pseudomonas sp.
    Biochimica et biophysica acta, 1962, May-21, Volume: 59

    Topics: Acetyl Coenzyme A; Biochemical Phenomena; Coenzyme A; Coenzymes; Pseudomonas; Pyruvates; Pyruvic Acid

1962
THE FORMATION OF ACETOACETATE FROM ACETYL COENZYME A, MALONYL COENZYME A,AND PYRUVATE BY WASHED MITOCHONDRIA ISOLATED FROM GUINEA PIG LIVER.
    Canadian journal of biochemistry and physiology, 1963, Volume: 41

    Topics: Acetates; Acetoacetates; Acetyl Coenzyme A; Adenosine Triphosphate; Antimetabolites; Bicarbonates; Biotin; Carbon Isotopes; Chromatography; Coenzyme A; Egg White; Guinea Pigs; Lipid Metabolism; Liver; Malonates; Malonyl Coenzyme A; Mitochondria; Pharmacology; Pyruvates; Pyruvic Acid; Research

1963
FAILURE OF ARSENATE TO UNCOUPLE THE PHOSPHOTRANSACETYLASE SYSTEM IN CLOSTRIDIUM ACIDIURICI.
    Journal of bacteriology, 1963, Volume: 86

    Topics: Acetyl Coenzyme A; Acetylesterase; Arsenates; Arsenicals; Clostridium; Coenzyme A; Metabolism; NAD; Pharmacology; Phosphate Acetyltransferase; Phosphates; Phosphorus Isotopes; Pyruvates; Pyruvic Acid; Radiometry; Research; Utah

1963
THE UTILIZATION OF ACONATE AND ITACONATE BY MICROCOCCUS SP.
    The Biochemical journal, 1965, Volume: 94

    Topics: Acetyl Coenzyme A; Aldehydes; Carbon Dioxide; Citric Acid Cycle; Coenzyme A; L-Lactate Dehydrogenase; Metabolism; Micrococcus; NAD; NADP; Oxidoreductases; Pyruvates; Pyruvic Acid; Research; Spectrophotometry; Succinates; Succinic Acid

1965
THE EFFECTS OF ADENINE NUCLEOTIDES ON PYRUVATE METABOLISM IN RAT LIVER.
    The Biochemical journal, 1965, Volume: 95

    Topics: Acetoacetates; Acetyl Coenzyme A; Adenine Nucleotides; Adenosine Triphosphate; Citric Acid Cycle; Coenzyme A; Dinitrophenols; Fumarates; Hexokinase; Hydroxybutyrates; Keto Acids; Liver; Mitochondria; Oxaloacetates; Oxidation-Reduction; Pharmacology; Pyruvates; Pyruvic Acid; Rats; Research

1965
Profiling substrate fluxes in the isolated working mouse heart using 13C-labeled substrates: focusing on the origin and fate of pyruvate and citrate carbons.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 286, Issue:4

    Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Animals; Carbon Isotopes; Citrates; Fatty Acids; Gas Chromatography-Mass Spectrometry; Glucose; Hemodynamics; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mitochondria, Heart; Myocardium; Oleic Acid; Oxaloacetic Acid; Oxidation-Reduction; Oxygen Consumption; Perfusion; Pyruvic Acid

2004
On the mechanism of action of the antifungal agent propionate.
    European journal of biochemistry, 2004, Volume: 271, Issue:15

    Topics: Acetate-CoA Ligase; Acetyl Coenzyme A; Acyl Coenzyme A; Antifungal Agents; Aspergillus nidulans; ATP Citrate (pro-S)-Lyase; Carbon; Coenzyme A-Transferases; Color; Culture Media; Glucose; Mutation; Oxidation-Reduction; Pentose Phosphate Pathway; Propionates; Pyruvic Acid; Spores

2004
Pyruvate dehydrogenase kinase isoform 2 activity limited and further inhibited by slowing down the rate of dissociation of ADP.
    Biochemistry, 2004, Oct-26, Volume: 43, Issue:42

    Topics: Acetyl Coenzyme A; Acetyltransferases; Adenosine Diphosphate; Adenosine Triphosphate; Binding, Competitive; Catalysis; Dichloroacetic Acid; Dihydrolipoyllysine-Residue Acetyltransferase; Enzyme Activation; Humans; Isoenzymes; Kinetics; Osmolar Concentration; Protein Binding; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein Subunits; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Substrate Specificity

2004
Plant biochemistry: green catalytic converter.
    Nature, 2004, Dec-09, Volume: 432, Issue:7018

    Topics: Acetyl Coenzyme A; Brassica napus; Carbon; Carbon Dioxide; Catalysis; Chlorophyll; Fatty Acids; Glycolysis; Photosynthesis; Plant Oils; Pyruvic Acid; Ribulose-Bisphosphate Carboxylase; Seeds

2004
Rubisco without the Calvin cycle improves the carbon efficiency of developing green seeds.
    Nature, 2004, Dec-09, Volume: 432, Issue:7018

    Topics: Acetyl Coenzyme A; Biomass; Brassica napus; Carbohydrate Metabolism; Carbon; Carbon Dioxide; Color; Fatty Acids; Glycolysis; Photosynthesis; Pigmentation; Plant Oils; Pyruvic Acid; Ribulose-Bisphosphate Carboxylase; Seeds

2004
The malaria parasite Plasmodium falciparum has only one pyruvate dehydrogenase complex, which is located in the apicoplast.
    Molecular microbiology, 2005, Volume: 55, Issue:1

    Topics: Acetyl Coenzyme A; Animals; Blotting, Western; DNA, Complementary; DNA, Protozoan; Erythrocytes; Genes, Reporter; Green Fluorescent Proteins; Introns; Molecular Sequence Data; Plasmodium falciparum; Plastids; Protein Subunits; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Sequence Analysis, DNA; Sequence Homology; Toxoplasma

2005
A defect in the acetyl coenzyme A<-->acetate pathway poisons recombinational repair-deficient mutants of Escherichia coli.
    Journal of bacteriology, 2005, Volume: 187, Issue:4

    Topics: Acetic Acid; Acetyl Coenzyme A; Adenosine Triphosphatases; Bacterial Proteins; DNA Helicases; DNA Repair; DNA-Binding Proteins; Endodeoxyribonucleases; Energy Metabolism; Escherichia coli; Escherichia coli Proteins; Exodeoxyribonuclease V; Gene Deletion; Mutagenesis, Insertional; Pyruvic Acid; Recombination, Genetic

2005
Tricarboxylic acid cycle inhibition by Li+ in the human neuroblastoma SH-SY5Y cell line: a 13C NMR isotopomer analysis.
    Neurochemistry international, 2005, Volume: 47, Issue:6

    Topics: Acetyl Coenzyme A; Antimanic Agents; Bipolar Disorder; Brain; Brain Chemistry; Carbon Isotopes; Cell Line, Tumor; Cell Survival; Citrate (si)-Synthase; Citric Acid Cycle; Dose-Response Relationship, Drug; Down-Regulation; Energy Metabolism; Feedback, Physiological; Glucose; Humans; Lactic Acid; Lithium; Magnetic Resonance Spectroscopy; Neuroblastoma; Neurons; Pyruvic Acid

2005
Quantitative 13C and 2H NMR relaxation studies of the 723-residue enzyme malate synthase G reveal a dynamic binding interface.
    Biochemistry, 2005, Dec-13, Volume: 44, Issue:49

    Topics: Acetyl Coenzyme A; Binding Sites; Carbon Isotopes; Deuterium; Isoenzymes; Isoleucine; Leucine; Malate Synthase; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Conformation; Pyruvic Acid; Valine

2005
Regulation of pyruvate carboxylation by acetyl-CoA in rat liver mitochondria.
    FEBS letters, 1976, Dec-31, Volume: 72, Issue:2

    Topics: Acetyl Coenzyme A; Allosteric Regulation; Animals; Mitochondria, Liver; Pyruvate Carboxylase; Pyruvic Acid; Rats

1976
Characterization of novel carbazole catabolism genes from gram-positive carbazole degrader Nocardioides aromaticivorans IC177.
    Applied and environmental microbiology, 2006, Volume: 72, Issue:5

    Topics: Acetyl Coenzyme A; Actinomycetales; Bacterial Proteins; Biodegradation, Environmental; Carbazoles; Molecular Sequence Data; Multigene Family; Operon; ortho-Aminobenzoates; Oxygenases; Pyruvic Acid; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA

2006
Mitochondrial metabolism in developing embryos of Brassica napus.
    The Journal of biological chemistry, 2006, Nov-10, Volume: 281, Issue:45

    Topics: Acetyl Coenzyme A; Amino Acids; Brassica napus; Carbohydrate Metabolism; Carbon; Carbon Isotopes; Citric Acid Cycle; Culture Techniques; Cytosol; Fatty Acids; Gas Chromatography-Mass Spectrometry; Glucose; Glycolysis; Isotope Labeling; Malates; Mitochondria; Models, Biological; Oxidative Phosphorylation; Protein Serine-Threonine Kinases; Pyruvic Acid; Seeds

2006
Antiparasitic drug nitazoxanide inhibits the pyruvate oxidoreductases of Helicobacter pylori, selected anaerobic bacteria and parasites, and Campylobacter jejuni.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:3

    Topics: Acetyl Coenzyme A; Animals; Antiprotozoal Agents; Bacteria, Anaerobic; Campylobacter jejuni; Carbon Dioxide; Cloning, Molecular; Clostridium; Culture Media; Enzyme Inhibitors; Helicobacter pylori; Kinetics; L-Lactate Dehydrogenase; Magnetic Resonance Spectroscopy; Nitro Compounds; Parasites; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Reverse Transcriptase Polymerase Chain Reaction; Thiamine Pyrophosphate; Thiazoles

2007
Mitochondrial fatty acid synthesis in Trypanosoma brucei.
    The Journal of biological chemistry, 2007, Feb-16, Volume: 282, Issue:7

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Acetyl Coenzyme A; Acyl Carrier Protein; Animals; Fatty Acids; Lipid Metabolism; Mitochondria; Protozoan Proteins; Pyruvic Acid; Sequence Deletion; Threonine; Trypanosoma brucei brucei

2007
Metabolic characterization of Escherichia coli strains adapted to growth on lactate.
    Applied and environmental microbiology, 2007, Volume: 73, Issue:14

    Topics: Acetyl Coenzyme A; Biomass; Carbon; Carbon Isotopes; Escherichia coli; Gene Expression Regulation, Bacterial; Gluconeogenesis; Lactic Acid; Metabolic Networks and Pathways; Oxaloacetic Acid; Phosphoenolpyruvate; Pyruvic Acid; Transcription, Genetic

2007
Elucidation of an alternate isoleucine biosynthesis pathway in Geobacter sulfurreducens.
    Journal of bacteriology, 2008, Volume: 190, Issue:7

    Topics: Acetyl Coenzyme A; Bacterial Proteins; Biosynthetic Pathways; Butyrates; Carbon Isotopes; Geobacter; Isoleucine; Malates; Pyruvic Acid; Threonine; Threonine Dehydratase

2008
Changes in enzyme activities at the pyruvate node in glutamate-overproducing Corynebacterium glutamicum.
    Journal of bioscience and bioengineering, 2008, Volume: 105, Issue:1

    Topics: Acetyl Coenzyme A; Bacterial Proteins; Corynebacterium glutamicum; Down-Regulation; Glutamic Acid; Industrial Microbiology; Oxaloacetic Acid; Pyruvate Carboxylase; Pyruvate Dehydrogenase Complex; Pyruvic Acid

2008
A dicarboxylate/4-hydroxybutyrate autotrophic carbon assimilation cycle in the hyperthermophilic Archaeum Ignicoccus hospitalis.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Jun-03, Volume: 105, Issue:22

    Topics: Acetyl Coenzyme A; Amino Acids; Carbon Dioxide; Carbon Isotopes; Desulfurococcaceae; Dicarboxylic Acids; Hydroxybutyrates; Proteins; Pyruvic Acid; Succinic Acid

2008
Hepatic anaplerotic outflow fluxes are redirected from gluconeogenesis to lactate synthesis in patients with Type 1a glycogen storage disease.
    Metabolic engineering, 2009, Volume: 11, Issue:3

    Topics: Acetyl Coenzyme A; Adolescent; Carbon Isotopes; Child; Citric Acid Cycle; Female; Gluconeogenesis; Glucose; Glucose-6-Phosphatase; Glutamine; Glycerol; Glycogen Storage Disease Type I; Humans; Lactates; Liver; Male; Pyruvic Acid; Young Adult

2009
Metabolic flux analysis of Escherichia coli creB and arcA mutants reveals shared control of carbon catabolism under microaerobic growth conditions.
    Journal of bacteriology, 2009, Volume: 191, Issue:17

    Topics: Acetyl Coenzyme A; Aerobiosis; Bacterial Outer Membrane Proteins; Carbon; Carbon Isotopes; Escherichia coli; Escherichia coli Proteins; Gene Deletion; Gene Expression Regulation, Bacterial; Glucose; Metabolic Networks and Pathways; Oxidation-Reduction; Oxygen; Pyruvic Acid; Repressor Proteins; Staining and Labeling

2009
Prior heavy exercise elevates pyruvate dehydrogenase activity and muscle oxygenation and speeds O2 uptake kinetics during moderate exercise in older adults.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 297, Issue:3

    Topics: Acetyl Coenzyme A; Adaptation, Physiological; Adenosine Diphosphate; Adenosine Triphosphate; Age Factors; Aged; Exercise; Humans; Kinetics; Lactic Acid; Male; Mitochondria, Muscle; Muscle, Skeletal; Oxygen; Oxygen Consumption; Phosphocreatine; Pulmonary Ventilation; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Regional Blood Flow; Spectroscopy, Near-Infrared; Up-Regulation

2009
Enzymatic and electron paramagnetic resonance studies of anabolic pyruvate synthesis by pyruvate: ferredoxin oxidoreductase from Hydrogenobacter thermophilus.
    The FEBS journal, 2010, Volume: 277, Issue:2

    Topics: Acetyl Coenzyme A; Bacteria; Bacterial Proteins; Carbon Dioxide; Citric Acid Cycle; Electron Spin Resonance Spectroscopy; Energy Metabolism; Ketone Oxidoreductases; Kinetics; L-Lactate Dehydrogenase; Pyruvate Synthase; Pyruvic Acid; Recombinant Proteins

2010
Metabolic flux analysis of wild-type Escherichia coli and mutants deficient in pyruvate-dissimilating enzymes during the fermentative metabolism of glucuronate.
    Microbiology (Reading, England), 2010, Volume: 156, Issue:Pt 6

    Topics: Acetyl Coenzyme A; Acetyltransferases; Escherichia coli; Escherichia coli Proteins; Fermentation; Glucuronates; NAD; Oxidation-Reduction; Pentose Phosphate Pathway; Pyruvic Acid

2010
Competition of pyruvate with physiological substrates for oxidation by the heart: implications for studies with hyperpolarized [1-13C]pyruvate.
    American journal of physiology. Heart and circulatory physiology, 2010, Volume: 298, Issue:5

    Topics: Acetyl Coenzyme A; Albumins; Animals; Carbon Radioisotopes; Cardiac Output; Coronary Vessels; Heart Function Tests; Hemodynamics; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Myocardium; Oxidation-Reduction; Oxygen Consumption; Pyruvic Acid; Rats; Rats, Sprague-Dawley

2010
Acetyl-CoA and acetylcholine metabolism in nerve terminal compartment of thiamine deficient rat brain.
    Journal of neurochemistry, 2010, Volume: 115, Issue:2

    Topics: Acetyl Coenzyme A; Acetylcholine; Animals; Brain; Citric Acid; Ketoglutarate Dehydrogenase Complex; Ketoglutaric Acids; Ketone Oxidoreductases; Lactic Acid; Male; Models, Biological; Nerve Endings; Pyrithiamine; Pyruvic Acid; Rats; Rats, Wistar; Synaptosomes; Thiamine Deficiency

2010
Both forward and reverse TCA cycles operate in green sulfur bacteria.
    The Journal of biological chemistry, 2010, Nov-12, Volume: 285, Issue:46

    Topics: Acetate Kinase; Acetates; Acetyl Coenzyme A; ATP Citrate (pro-S)-Lyase; Autotrophic Processes; Bacterial Proteins; Biomass; Carbon; Carbon Isotopes; Chlorobi; Citric Acid Cycle; Coenzyme A Ligases; Gene Expression Regulation, Bacterial; Lactic Acid; Metabolic Networks and Pathways; Models, Biological; Molecular Structure; Pyruvic Acid; Reverse Transcriptase Polymerase Chain Reaction

2010
Metabolomics of supragingival plaque and oral bacteria.
    Journal of dental research, 2010, Volume: 89, Issue:12

    Topics: Acetyl Coenzyme A; Actinomyces; Adult; Bacteriological Techniques; Carbon; Citric Acid Cycle; Dental Plaque; Dihydroxyacetone Phosphate; Female; Fructosediphosphates; Fructosephosphates; Fumarates; Gluconates; Glucose; Glucose-6-Phosphate; Glyceric Acids; Glycolysis; Humans; Malates; Male; Metabolomics; Pentose Phosphate Pathway; Phosphoenolpyruvate; Pyruvic Acid; Ribulosephosphates; Streptococcus; Streptococcus mutans; Succinic Acid; Sugar Phosphates

2010
The cycling of acetyl-coenzyme A through acetylcarnitine buffers cardiac substrate supply: a hyperpolarized 13C magnetic resonance study.
    Circulation. Cardiovascular imaging, 2012, Volume: 5, Issue:2

    Topics: Acetyl Coenzyme A; Acetylcarnitine; Animals; Carbon Isotopes; Carnitine O-Acetyltransferase; Citric Acid; Energy Metabolism; Glutamic Acid; Magnetic Resonance Spectroscopy; Male; Myocardial Contraction; Myocardium; Oxidation-Reduction; Postprandial Period; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Rats; Rats, Wistar; Time Factors

2012
Influence of dichloroacetate (DCA) on lactate production and oxygen consumption in neuroblastoma cells: is DCA a suitable drug for neuroblastoma therapy?
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2012, Volume: 29, Issue:3-4

    Topics: Acetyl Coenzyme A; Apoptosis; Cell Line, Tumor; Cell Proliferation; Citric Acid Cycle; Culture Media; Dichloroacetic Acid; Drug Screening Assays, Antitumor; Enzyme Activation; Humans; Lactic Acid; Mitochondria; Neuroblastoma; Oxidative Phosphorylation; Oxygen; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Reactive Oxygen Species

2012
Quantitative importance of the pentose phosphate pathway determined by incorporation of 13C from [2-13C]- and [3-13C]glucose into TCA cycle intermediates and neurotransmitter amino acids in functionally intact neurons.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2012, Volume: 32, Issue:9

    Topics: Acetyl Coenzyme A; Amino Acids; Animals; Carbon Isotopes; Cells, Cultured; Citric Acid Cycle; Female; Glucose; Glycolysis; Magnetic Resonance Spectroscopy; Mice; Neurons; Neurotransmitter Agents; Oxidation-Reduction; Pentose Phosphate Pathway; Pregnancy; Pyruvic Acid

2012
Heptanoate as a neural fuel: energetic and neurotransmitter precursors in normal and glucose transporter I-deficient (G1D) brain.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2013, Volume: 33, Issue:2

    Topics: Acetyl Coenzyme A; Animals; Anticonvulsants; Brain; Brain Chemistry; Energy Metabolism; Glucose; Glucose Transporter Type 1; Glutamine; Heptanoates; Magnetic Resonance Spectroscopy; Mice; Mice, Transgenic; Pyruvic Acid; Seizures; Triglycerides

2013
Does acetogenesis really require especially low reduction potential?
    Biochimica et biophysica acta, 2013, Volume: 1827, Issue:3

    Topics: Acetates; Acetyl Coenzyme A; Aldehyde Oxidoreductases; Carbon Dioxide; Multienzyme Complexes; Oxidation-Reduction; Pyruvate Synthase; Pyruvic Acid; Thermodynamics

2013
Chlamydomonas reinhardtii chloroplasts contain a homodimeric pyruvate:ferredoxin oxidoreductase that functions with FDX1.
    Plant physiology, 2013, Volume: 161, Issue:1

    Topics: Acetyl Coenzyme A; Amino Acid Sequence; Benzyl Viologen; Chlamydomonas reinhardtii; Chloroplast Proteins; Chloroplasts; Electron Spin Resonance Spectroscopy; Electron Transport; Electrophoresis, Polyacrylamide Gel; Energy Metabolism; Enzyme Activation; Escherichia coli; Ferredoxins; Immunoblotting; Iron-Sulfur Proteins; Molecular Sequence Data; Oxidation-Reduction; Pyruvate Decarboxylase; Pyruvate Synthase; Pyruvic Acid; Recombinant Proteins; Solubility; Thiamine Pyrophosphate

2013
Myocardial oxidative metabolism and protein synthesis during mechanical circulatory support by extracorporeal membrane oxygenation.
    American journal of physiology. Heart and circulatory physiology, 2013, Feb-01, Volume: 304, Issue:3

    Topics: Acetyl Coenzyme A; Animals; Blood Pressure; Citric Acid Cycle; Extracorporeal Membrane Oxygenation; Gas Chromatography-Mass Spectrometry; Heart; Heart Rate; Hemoglobins; Interleukin-6; Leucine; Magnetic Resonance Spectroscopy; Male; Mitochondria, Heart; Myocardium; Oxidation-Reduction; Protein Biosynthesis; Pyruvic Acid; Swine

2013
Fermentative 2-carbon metabolism produces carcinogenic levels of acetaldehyde in Candida albicans.
    Molecular oral microbiology, 2013, Volume: 28, Issue:4

    Topics: Acetaldehyde; Acetate-CoA Ligase; Acetyl Coenzyme A; Alcohol Dehydrogenase; Aldehyde Oxidoreductases; Candida albicans; Candidiasis, Chronic Mucocutaneous; Candidiasis, Oral; Carbon; Carcinoma, Squamous Cell; Cariogenic Agents; Ethanol; Fermentation; Fungal Proteins; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Glucose; Humans; Mouth Neoplasms; Oxygen; Polyendocrinopathies, Autoimmune; Pyruvate Decarboxylase; Pyruvic Acid

2013
A liver-specific defect of Acyl-CoA degradation produces hyperammonemia, hypoglycemia and a distinct hepatic Acyl-CoA pattern.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Carbon Dioxide; Gene Knockout Techniques; Gene Order; Gene Targeting; Genes, Lethal; Gluconeogenesis; Hepatocytes; Humans; Hyperammonemia; Hypoglycemia; Lethargy; Leucine; Liver; Metabolic Networks and Pathways; Metabolome; Mice; Mice, Knockout; Mitochondria; Models, Biological; Peroxisomes; Phenotype; Pyruvic Acid

2013
A synthetic biochemistry system for the in vitro production of isoprene from glycolysis intermediates.
    Protein science : a publication of the Protein Society, 2014, Volume: 23, Issue:5

    Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Biosynthetic Pathways; Butadienes; Escherichia coli; Glycolysis; Green Chemistry Technology; Hemiterpenes; Metabolic Engineering; Mevalonic Acid; NADP; Pentanes; Phosphoenolpyruvate; Pyruvic Acid

2014
Acetate kinase isozymes confer robustness in acetate metabolism.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Acetate Kinase; Acetates; Acetyl Coenzyme A; Base Sequence; Conserved Sequence; Genes, Bacterial; Isoenzymes; Kinetics; Lactic Acid; Lactococcus lactis; Maltose; Molecular Sequence Data; Mutation; Phylogeny; Pyruvic Acid; Sequence Homology, Amino Acid; Species Specificity; Terminator Regions, Genetic; Transcription Initiation Site

2014
Structure and function of the catalytic domain of the dihydrolipoyl acetyltransferase component in Escherichia coli pyruvate dehydrogenase complex.
    The Journal of biological chemistry, 2014, May-30, Volume: 289, Issue:22

    Topics: Acetyl Coenzyme A; Acetylation; Amino Acid Sequence; Carbohydrate Metabolism; Catalytic Domain; Crystallography, X-Ray; Deuterium Exchange Measurement; Dihydrolipoyllysine-Residue Acetyltransferase; Enzyme Activation; Escherichia coli; Escherichia coli Proteins; Molecular Sequence Data; Plasmids; Pyruvate Dehydrogenase Complex; Pyruvic Acid

2014
Effects of pyruvate dehydrogenase subunits overexpression on the α-ketoglutarate production in Yarrowia lipolytica WSH-Z06.
    Applied microbiology and biotechnology, 2014, Volume: 98, Issue:16

    Topics: Acetyl Coenzyme A; Gene Expression; Ketoglutaric Acids; Metabolic Engineering; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Thiamine; Yarrowia

2014
c-Myc programs fatty acid metabolism and dictates acetyl-CoA abundance and fate.
    The Journal of biological chemistry, 2014, Sep-05, Volume: 289, Issue:36

    Topics: Acetyl Coenzyme A; Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Blotting, Western; Cell Line, Tumor; Citric Acid Cycle; Fatty Acids; Fibroblasts; Gene Expression Profiling; Gene Knockout Techniques; Glycolysis; Humans; Ketone Oxidoreductases; Lipid Metabolism; Metabolic Networks and Pathways; Oxidation-Reduction; Oxidative Phosphorylation; Proto-Oncogene Proteins c-myc; Pyruvic Acid; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference

2014
Metabolic regulation of phytoplasma malic enzyme and phosphotransacetylase supports the use of malate as an energy source in these plant pathogens.
    Microbiology (Reading, England), 2014, Volume: 160, Issue:Pt 12

    Topics: Acetyl Coenzyme A; Carbon Dioxide; Energy Metabolism; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Malate Dehydrogenase; Malates; NAD; NADP; Phosphate Acetyltransferase; Phytoplasma; Pyruvic Acid

2014
Propionate stimulates pyruvate oxidation in the presence of acetate.
    American journal of physiology. Heart and circulatory physiology, 2014, Oct-15, Volume: 307, Issue:8

    Topics: Acetates; Acetyl Coenzyme A; Animals; Bicarbonates; Glucose; Heart; Mice; Mice, Inbred C57BL; Myocardium; Oxidation-Reduction; Propionates; Pyruvate Dehydrogenase (Lipoamide); Pyruvic Acid; Substrate Specificity

2014
Glutamine oxidation maintains the TCA cycle and cell survival during impaired mitochondrial pyruvate transport.
    Molecular cell, 2014, Nov-06, Volume: 56, Issue:3

    Topics: Acetyl Coenzyme A; Animals; Antineoplastic Agents; Biological Transport; Catechin; Cell Line, Tumor; Cell Survival; Citric Acid; Citric Acid Cycle; Coumaric Acids; Glucose; Glutamine; Humans; Lipid Metabolism; Male; Mice, Nude; Mitochondria; Oxidation-Reduction; Pyruvic Acid; Sugar Alcohol Dehydrogenases; Tumor Burden; Xenograft Model Antitumor Assays

2014
Therapeutic hypothermia achieves neuroprotection via a decrease in acetylcholine with a concurrent increase in carnitine in the neonatal hypoxia-ischemia.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2015, Volume: 35, Issue:5

    Topics: Acetyl Coenzyme A; Acetylcholine; Amino Acids; Amygdala; Animals; Animals, Newborn; Carnitine; Glycolysis; Hippocampus; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Male; Mass Spectrometry; Pyruvic Acid; Rats; Rats, Sprague-Dawley

2015
¹³C-based metabolic flux analysis of Saccharomyces cerevisiae with a reduced Crabtree effect.
    Journal of bioscience and bioengineering, 2015, Volume: 120, Issue:2

    Topics: Acetyl Coenzyme A; Aerobiosis; Biomass; Ethanol; Glucose; Glycolysis; Metabolic Flux Analysis; NADP; Oxidation-Reduction; Pentose Phosphate Pathway; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Saccharomyces cerevisiae

2015
Mesaconase Activity of Class I Fumarase Contributes to Mesaconate Utilization by Burkholderia xenovorans.
    Applied and environmental microbiology, 2015, Aug-15, Volume: 81, Issue:16

    Topics: Acetyl Coenzyme A; Burkholderia; Fumarate Hydratase; Fumarates; Hydro-Lyases; Kinetics; Malates; Maleates; Metabolic Networks and Pathways; Pyruvic Acid; Substrate Specificity; Succinates

2015
Residues in the acetyl CoA binding site of pyruvate carboxylase involved in allosteric regulation.
    FEBS letters, 2015, Jul-22, Volume: 589, Issue:16

    Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Allosteric Regulation; Allosteric Site; Amino Acid Substitution; Arginine; Aspartic Acid; Bacterial Proteins; Bicarbonates; Biocatalysis; Glutamic Acid; Kinetics; Magnesium; Models, Molecular; Molecular Conformation; Mutagenesis, Site-Directed; Mutant Proteins; Protein Stability; Pyruvate Carboxylase; Pyruvic Acid; Recombinant Proteins; Rhizobium etli

2015
Ketone bodies effectively compete with glucose for neuronal acetyl-CoA generation in rat hippocampal slices.
    NMR in biomedicine, 2015, Volume: 28, Issue:9

    Topics: Acetates; Acetyl Coenzyme A; Animals; Citric Acid Cycle; Glucose; Glycolysis; Hippocampus; Ketone Bodies; Male; Neurons; Pyruvic Acid; Rats; Rats, Wistar

2015
Characterization of glucose-related metabolic pathways in differentiated rat oligodendrocyte lineage cells.
    Glia, 2016, Volume: 64, Issue:1

    Topics: Acetates; Acetyl Coenzyme A; Animals; Carbon Radioisotopes; Cells, Cultured; Citric Acid Cycle; Cytosol; Glucose; Lactic Acid; Malates; Mitochondria; Neural Stem Cells; Oligodendroglia; Oxaloacetic Acid; Pentose Phosphate Pathway; Phosphoenolpyruvate; Pyruvic Acid; Radiopharmaceuticals; Rats, Sprague-Dawley

2016
Manipulating pyruvate to acetyl-CoA conversion in Escherichia coli for anaerobic succinate biosynthesis from glucose with the yield close to the stoichiometric maximum.
    Journal of biotechnology, 2015, Nov-20, Volume: 214

    Topics: Acetyl Coenzyme A; Acetyltransferases; Anaerobiosis; Escherichia coli; Escherichia coli Proteins; Glucose; Metabolic Engineering; Metabolic Networks and Pathways; Pyruvic Acid; Succinic Acid

2015
AβPP-Transgenic 2576 Mice Mimic Cell Type-Specific Aspects of Acetyl-CoA-Linked Metabolic Deficits in Alzheimer's Disease.
    Journal of Alzheimer's disease : JAD, 2015, Volume: 48, Issue:4

    Topics: Acetyl Coenzyme A; Acetylcholine; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Citric Acid; Cytoplasm; Disease Models, Animal; Female; Humans; Ketoglutaric Acids; Male; Mice, Transgenic; Mitochondria; Mutation; Neuroglia; Neurons; Peptide Fragments; Pyruvic Acid; Synaptosomes

2015
Integrated, Step-Wise, Mass-Isotopomeric Flux Analysis of the TCA Cycle.
    Cell metabolism, 2015, Nov-03, Volume: 22, Issue:5

    Topics: Acetyl Coenzyme A; Animals; Carbon Isotopes; Citrates; Citric Acid; Citric Acid Cycle; Insulin; Isocitrate Dehydrogenase; Oxaloacetic Acid; Oxidation-Reduction; Oxygen Consumption; Pyruvate Carboxylase; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Rats

2015
Impaired energy metabolism of the taurine‑deficient heart.
    Amino acids, 2016, Volume: 48, Issue:2

    Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Animals; Carnitine O-Palmitoyltransferase; Citric Acid Cycle; Electron Transport; Energy Metabolism; Glucose; Glycolysis; Heart; Magnesium; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; NAD; Oxidation-Reduction; Palmitates; Pyruvic Acid; Rats; Rats, Wistar; Taurine

2016
Alternative reactions at the interface of glycolysis and citric acid cycle in Saccharomyces cerevisiae.
    FEMS yeast research, 2016, Volume: 16, Issue:3

    Topics: Acetyl Coenzyme A; Citrate (si)-Synthase; Citric Acid Cycle; Coenzyme A-Transferases; Gene Deletion; Gene Expression; Glycolysis; Metabolic Engineering; Metabolic Flux Analysis; Metabolic Networks and Pathways; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins

2016
Transport of pyruvate into mitochondria is involved in methylmercury toxicity.
    Scientific reports, 2016, Feb-22, Volume: 6

    Topics: Acetyl Coenzyme A; Acetylcysteine; Antioxidants; Cytoplasm; Humans; Lactate Dehydrogenases; Methylmercury Compounds; Mitochondria; Neuroblastoma; Phosphopyruvate Hydratase; Pyruvic Acid; Reactive Oxygen Species; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins

2016
Exogenous pyruvate facilitates cancer cell adaptation to hypoxia by serving as an oxygen surrogate.
    Oncotarget, 2016, Jul-26, Volume: 7, Issue:30

    Topics: Acetyl Coenzyme A; Adaptation, Physiological; Adenosine Triphosphate; Cell Proliferation; Electron Transport; Glycolysis; Humans; NAD; Neoplasms; Oxaloacetic Acid; Oxygen; Pyruvic Acid; TOR Serine-Threonine Kinases

2016
An Artificial Reaction Promoter Modulates Mitochondrial Functions via Chemically Promoting Protein Acetylation.
    Scientific reports, 2016, 07-04, Volume: 6

    Topics: Acetyl Coenzyme A; Acetylation; Adenosine Triphosphate; Cytoplasm; DNA Fragmentation; DNA, Mitochondrial; Fluorescent Dyes; HEK293 Cells; HeLa Cells; Humans; Mitochondria; Mitochondrial Proteins; Phosphines; Pyruvic Acid

2016
Comprehensive metabolic modeling of multiple 13C-isotopomer data sets to study metabolism in perfused working hearts.
    American journal of physiology. Heart and circulatory physiology, 2016, 10-01, Volume: 311, Issue:4

    Topics: Acetyl Coenzyme A; Animals; Carbon Isotopes; Energy Metabolism; Glucose; Isolated Heart Preparation; Lactic Acid; Male; Metabolic Flux Analysis; Metabolic Networks and Pathways; Mice; Models, Biological; Models, Cardiovascular; Myocardium; Oleic Acid; Pyruvic Acid

2016
Lipogenesis and Redox Balance in Nitrogen-Fixing Pea Bacteroids.
    Journal of bacteriology, 2016, 10-15, Volume: 198, Issue:20

    Topics: Acetyl Coenzyme A; Bacterial Proteins; Carbon; Citric Acid Cycle; Hydroxybutyrates; Lipogenesis; Nitrogen; Oxidation-Reduction; Pisum sativum; Polyesters; Pyruvic Acid; Rhizobium leguminosarum; Symbiosis

2016
Breast Cancer-Derived Lung Metastases Show Increased Pyruvate Carboxylase-Dependent Anaplerosis.
    Cell reports, 2016, 10-11, Volume: 17, Issue:3

    Topics: Acetyl Coenzyme A; Adenosine Diphosphate; Adenosine Triphosphate; Breast Neoplasms; Carbon Isotopes; Cell Compartmentation; Cell Line, Tumor; Citric Acid Cycle; Cytosol; Female; Humans; Isotope Labeling; Lung Neoplasms; Mitochondria; Pyruvate Carboxylase; Pyruvic Acid; Tumor Microenvironment

2016
The Role of the Pyruvate Acetyl-CoA Switch in the Production of 1,3-Propanediol by Klebsiella pneumoniae.
    Applied biochemistry and biotechnology, 2017, Volume: 181, Issue:3

    Topics: Acetyl Coenzyme A; Gene Deletion; Genes, Bacterial; Glycerol; Klebsiella pneumoniae; Propylene Glycols; Pyruvic Acid

2017
Evidence for impaired glucose metabolism in the striatum, obtained postmortem, from some subjects with schizophrenia.
    Translational psychiatry, 2016, 11-15, Volume: 6, Issue:11

    Topics: Acetyl Coenzyme A; Adult; Blood Glucose; Case-Control Studies; Corpus Striatum; Energy Metabolism; Female; History, 16th Century; History, 17th Century; Humans; Lactic Acid; Male; Middle Aged; Neural Pathways; Pyruvate Dehydrogenase (Lipoamide); Pyruvic Acid; Receptors, Muscarinic; Reference Values; Schizophrenia

2016
Mass spectrometry analysis shows the biosynthetic pathways supported by pyruvate carboxylase in highly invasive breast cancer cells.
    Biochimica et biophysica acta. Molecular basis of disease, 2017, Volume: 1863, Issue:2

    Topics: Acetyl Coenzyme A; Aspartic Acid; Biosynthetic Pathways; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Citric Acid; Female; Gene Knockdown Techniques; Glycine; Glycolysis; Humans; Lactic Acid; Malates; Mass Spectrometry; Metabolic Networks and Pathways; Neoplasm Invasiveness; Nucleotides; Pyruvate Carboxylase; Pyruvic Acid; Serine

2017
Loss of Cardiolipin Leads to Perturbation of Acetyl-CoA Synthesis.
    The Journal of biological chemistry, 2017, 01-20, Volume: 292, Issue:3

    Topics: Acetyl Coenzyme A; Cardiolipins; Coenzyme A Ligases; Pyruvic Acid; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins

2017
Reengineering of the human pyruvate dehydrogenase complex: from disintegration to highly active agglomerates.
    The Biochemical journal, 2017, 02-20, Volume: 474, Issue:5

    Topics: Acetyl Coenzyme A; Amino Acid Sequence; Animals; Catalytic Domain; Cloning, Molecular; Dihydrolipoamide Dehydrogenase; Dihydrolipoyllysine-Residue Acetyltransferase; Escherichia coli; Gene Expression; Humans; Kinetics; Mutation; Protein Engineering; Protein Multimerization; Protein Structure, Secondary; Pyruvate Dehydrogenase (Lipoamide); Pyruvate Dehydrogenase Complex; Pyruvic Acid; Recombinant Proteins; Structure-Activity Relationship

2017
STAT3 Undergoes Acetylation-dependent Mitochondrial Translocation to Regulate Pyruvate Metabolism.
    Scientific reports, 2016, 12-22, Volume: 6

    Topics: A549 Cells; Acetyl Coenzyme A; Acetylation; Animals; Cell Line, Tumor; Cell Nucleus; Citric Acid Cycle; Cytoplasm; Fibroblasts; HEK293 Cells; HeLa Cells; Humans; Insulin; Membrane Potential, Mitochondrial; Mice; Mitochondria; Oxidation-Reduction; Protein Processing, Post-Translational; Protein Transport; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; STAT3 Transcription Factor

2016
ACSS2-mediated acetyl-CoA synthesis from acetate is necessary for human cytomegalovirus infection.
    Proceedings of the National Academy of Sciences of the United States of America, 2017, 02-21, Volume: 114, Issue:8

    Topics: Acetate-CoA Ligase; Acetic Acid; Acetyl Coenzyme A; ATP Citrate (pro-S)-Lyase; Cell Line, Tumor; CRISPR-Cas Systems; Cytomegalovirus; Cytomegalovirus Infections; Cytosol; Fibroblasts; Gene Expression Regulation, Enzymologic; Gene Knockout Techniques; Glucose; Glycolysis; Host-Pathogen Interactions; Humans; Lipogenesis; Mitochondria; Primary Cell Culture; Pyruvic Acid; RNA Interference; RNA, Small Interfering

2017
Synthetic metabolic bypass for a metabolic toggle switch enhances acetyl-CoA supply for isopropanol production by Escherichia coli.
    Journal of bioscience and bioengineering, 2017, Volume: 123, Issue:5

    Topics: 2-Propanol; Acetyl Coenzyme A; Biosynthetic Pathways; Citric Acid Cycle; Escherichia coli; Escherichia coli Proteins; Glucose; Glycolysis; Metabolic Engineering; Metabolic Flux Analysis; Pyruvic Acid

2017
Dynamic metabolic profiling together with transcription analysis reveals salinity-induced starch-to-lipid biosynthesis in alga Chlamydomonas sp. JSC4.
    Scientific reports, 2017, 04-04, Volume: 7

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Biofuels; Biomass; Carbon; Chlamydomonas; Gene Expression Profiling; Lipid Metabolism; Lipids; Metabolomics; Pyruvate Decarboxylase; Pyruvic Acid; Salts; Starch; Starch Phosphorylase

2017
Iron catalysis at the origin of life.
    IUBMB life, 2017, Volume: 69, Issue:6

    Topics: Acetyl Coenzyme A; Archaea; Bacteria; Carbon Cycle; Carbon Dioxide; Catalysis; Citric Acid Cycle; Ferredoxins; Hydrogen-Ion Concentration; Hydrothermal Vents; Iron; Iron-Sulfur Proteins; Ketoglutaric Acids; Origin of Life; Oxaloacetic Acid; Protons; Pyruvic Acid

2017
Kinetic and Thermodynamic Analysis of Acetyl-CoA Activation of Staphylococcus aureus Pyruvate Carboxylase.
    Biochemistry, 2017, 07-11, Volume: 56, Issue:27

    Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Algorithms; Allosteric Regulation; Bacterial Proteins; Binding Sites; Biocatalysis; Energy Transfer; Enzyme Activation; Enzyme Stability; Kinetics; Magnesium; Models, Molecular; Molecular Conformation; Protein Conformation; Protein Interaction Domains and Motifs; Protein Refolding; Pyruvate Carboxylase; Pyruvic Acid; Recombinant Proteins; Staphylococcus aureus; Thermodynamics

2017
Eliminating acetate formation improves citramalate production by metabolically engineered Escherichia coli.
    Microbial cell factories, 2017, Jun-21, Volume: 16, Issue:1

    Topics: Acetates; Acetyl Coenzyme A; Aerobiosis; Batch Cell Culture Techniques; Escherichia coli; Gene Deletion; Genes, Bacterial; Malates; Metabolic Engineering; Mutation; Pyruvic Acid

2017
Acetyl-CoA production from pyruvate is not necessary for preservation of myelin.
    Glia, 2017, Volume: 65, Issue:10

    Topics: 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase; Acetyl Coenzyme A; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antigens; Female; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myelin P0 Protein; Myelin Sheath; Nerve Tissue Proteins; Neural Conduction; Optic Nerve; Proteoglycans; Pyruvate Dehydrogenase Complex; Pyruvate Dehydrogenase Complex Deficiency Disease; Pyruvic Acid; Sciatic Nerve

2017
Genetic Dissociation of Glycolysis and the TCA Cycle Affects Neither Normal nor Neoplastic Proliferation.
    Cancer research, 2017, 11-01, Volume: 77, Issue:21

    Topics: Acetyl Coenzyme A; Animals; Cell Proliferation; Cells, Cultured; Citric Acid Cycle; Female; Glycolysis; Hepatoblastoma; Hepatocytes; Immunoblotting; Mice, Knockout; Mitochondrial Proteins; Oxidative Phosphorylation; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Survival Analysis; Tandem Mass Spectrometry

2017
Efficient bio-production of citramalate using an engineered Escherichia coli strain.
    Microbiology (Reading, England), 2018, Volume: 164, Issue:2

    Topics: Acetyl Coenzyme A; Acetyltransferases; Batch Cell Culture Techniques; Escherichia coli; Escherichia coli Proteins; Fermentation; Genes, Bacterial; Malates; Metabolic Engineering; Methanocaldococcus; Pyruvic Acid; Recombinant Proteins

2018
Acetyl-CoA from inflammation-induced fatty acids oxidation promotes hepatic malate-aspartate shuttle activity and glycolysis.
    American journal of physiology. Endocrinology and metabolism, 2018, 10-01, Volume: 315, Issue:4

    Topics: Acetyl Coenzyme A; Acetylation; Animals; Aspartate Aminotransferase, Mitochondrial; Aspartic Acid; Carbon Isotopes; Fatty Acids; Glycolysis; Inflammation; Lactic Acid; Lipopolysaccharides; Liver; Malate Dehydrogenase; Malates; Mitochondria, Liver; Oxidation-Reduction; Palmitic Acid; Pyruvic Acid; Stress, Physiological; Sus scrofa; Swine

2018
Propionate-induced changes in cardiac metabolism, notably CoA trapping, are not altered by l-carnitine.
    American journal of physiology. Endocrinology and metabolism, 2018, 10-01, Volume: 315, Issue:4

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Carnitine; Citric Acid Cycle; Coenzyme A; Energy Metabolism; Fatty Acids; Glucose; Heart; Isolated Heart Preparation; Liver; Malates; Male; Metabolic Flux Analysis; Mitochondria, Heart; Myocardium; Oxidation-Reduction; Propionates; Pyruvic Acid; Rats

2018
Liquid Chromatography-Tandem Mass Spectrometry Method Revealed that Lung Cancer Cells Exhibited Distinct Metabolite Profiles upon the Treatment with Different Pyruvate Dehydrogenase Kinase Inhibitors.
    Journal of proteome research, 2018, 09-07, Volume: 17, Issue:9

    Topics: A549 Cells; Acetyl Coenzyme A; Anilides; Antineoplastic Agents; Chromatography, Liquid; Citric Acid Cycle; Cytosol; Dichloroacetic Acid; Gene Expression Regulation; Glucose; Glycolysis; Humans; Isoenzymes; Lactic Acid; Mitochondria; Oxidative Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvic Acid; Tandem Mass Spectrometry

2018
Acetate Production from Glucose and Coupling to Mitochondrial Metabolism in Mammals.
    Cell, 2018, 10-04, Volume: 175, Issue:2

    Topics: Acetates; Acetyl Coenzyme A; Acetylation; Animals; ATP Citrate (pro-S)-Lyase; Female; Glucose; Glycolysis; Lipogenesis; Male; Mammals; Mice; Mice, Inbred C57BL; Mitochondria; Oxidoreductases; Pyruvate Decarboxylase; Pyruvic Acid; Reactive Oxygen Species

2018
Synthetic redesign of central carbon and redox metabolism for high yield production of N-acetylglucosamine in Bacillus subtilis.
    Metabolic engineering, 2019, Volume: 51

    Topics: Acetyl Coenzyme A; Acetylglucosamine; Bacillus subtilis; Carbon; DNA, Bacterial; Gene Knockout Techniques; Glucose; Metabolic Engineering; NADP; Oxidation-Reduction; Polymerase Chain Reaction; Pyruvic Acid

2019
Proteomic analysis reveals that sugar and fatty acid metabolisms play a central role in sterility of the male-sterile line 1355A of cotton.
    The Journal of biological chemistry, 2019, 04-26, Volume: 294, Issue:17

    Topics: Acetyl Coenzyme A; Carboxylic Acids; Fatty Acids; Glycolysis; Gossypium; Oxidation-Reduction; Plant Proteins; Pollen; Proteomics; Pyruvic Acid

2019
Impact of Five Succinate Dehydrogenase Inhibitors on DON Biosynthesis of
    Toxins, 2019, 05-15, Volume: 11, Issue:5

    Topics: Acetyl Coenzyme A; Citric Acid; Fungal Proteins; Fungicides, Industrial; Fusarium; Gene Expression; Glycolysis; Isocitrate Dehydrogenase; Mitochondria; Mycelium; Plant Diseases; Pyruvic Acid; Spores, Fungal; Succinate Dehydrogenase; Trichothecenes; Triticum

2019
Pyruvate Dehydrogenase Kinase Is a Metabolic Checkpoint for Polarization of Macrophages to the M1 Phenotype.
    Frontiers in immunology, 2019, Volume: 10

    Topics: Acetyl Coenzyme A; Animals; Cytosol; Diet, High-Fat; Insulin Resistance; Macrophage Activation; Macrophages; Male; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Obesity; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvate Dehydrogenase Complex; Pyruvic Acid

2019
Remodeling of substrate consumption in the murine sTAC model of heart failure.
    Journal of molecular and cellular cardiology, 2019, Volume: 134

    Topics: Acetyl Coenzyme A; Animals; Aorta; Citric Acid Cycle; Constriction; Disease Models, Animal; Energy Metabolism; Heart; Heart Failure; Male; Metabolome; Metabolomics; Mice; Mice, Inbred C57BL; Myocardium; Oxidation-Reduction; Pyruvic Acid

2019
Mevalonate production from ethanol by direct conversion through acetyl-CoA using recombinant Pseudomonas putida, a novel biocatalyst for terpenoid production.
    Microbial cell factories, 2019, Oct-10, Volume: 18, Issue:1

    Topics: Acetyl Coenzyme A; Biofuels; Ethanol; Metabolic Engineering; Mevalonic Acid; Microorganisms, Genetically-Modified; Pseudomonas putida; Pyruvic Acid; Terpenes

2019
Differential Metabolomic Analysis of Liver Tissues from Rat Models of Parenteral Nutrition-Associated Liver Disease.
    BioMed research international, 2020, Volume: 2020

    Topics: Acetyl Coenzyme A; Animals; Bile Acids and Salts; Choline; Enteral Nutrition; Fatty Acids, Unsaturated; Liver; Liver Diseases; Male; Metabolomics; Parenteral Nutrition; Phosphatidylcholines; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Riboflavin; Taurine

2020
Assessment of organic acid accumulation and its related genes in peach.
    Food chemistry, 2021, Jan-01, Volume: 334

    Topics: Acetyl Coenzyme A; Carboxylic Acids; Citric Acid; Fruit; Gene Expression Profiling; Gene Expression Regulation, Plant; Malates; Plant Proteins; Prunus persica; Pyruvic Acid; Vacuoles

2021
Dichloroacetate-induced metabolic reprogramming improves lifespan in a Drosophila model of surviving sepsis.
    PloS one, 2020, Volume: 15, Issue:11

    Topics: Acetyl Coenzyme A; Animals; Citric Acid Cycle; Dichloroacetic Acid; Drosophila melanogaster; Glycolysis; Inflammation; Lactic Acid; Longevity; Oxidative Phosphorylation; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Sepsis

2020
Mitochondria as a Platform for Dictating the Cell Fate of Cultured Human Corneal Endothelial Cells.
    Investigative ophthalmology & visual science, 2020, 12-01, Volume: 61, Issue:14

    Topics: Acetyl Coenzyme A; Cells, Cultured; Citric Acid Cycle; Endothelium, Corneal; Gas Chromatography-Mass Spectrometry; Humans; Mitochondria; Oxygen; Pyruvic Acid

2020
Glucose Metabolism and Acetate Switch in Archaea: the Enzymes in Haloferax volcanii.
    Journal of bacteriology, 2021, 03-23, Volume: 203, Issue:8

    Topics: Acetate-CoA Ligase; Acetates; Acetyl Coenzyme A; Archaeal Proteins; Glucose; Haloferax volcanii; Phosphoenolpyruvate Carboxylase; Phosphoglycerate Mutase; Phosphopyruvate Hydratase; Pyruvic Acid

2021
Balancing energy demand and production by mitochondrial trafficking of RHEB.
    Developmental cell, 2021, 03-22, Volume: 56, Issue:6

    Topics: Acetyl Coenzyme A; Energy Metabolism; Mitochondria; Pyruvate Dehydrogenase Complex; Pyruvic Acid

2021
High CO
    Nature, 2021, Volume: 592, Issue:7856

    Topics: Acetyl Coenzyme A; ATP Citrate (pro-S)-Lyase; Autotrophic Processes; Bacterial Proteins; Carbon; Carbon Dioxide; Citric Acid Cycle; Deltaproteobacteria; Partial Pressure; Pyruvic Acid

2021
Hyperpolarized NMR study of the impact of pyruvate dehydrogenase kinase inhibition on the pyruvate dehydrogenase and TCA flux in type 2 diabetic rat muscle.
    Pflugers Archiv : European journal of physiology, 2021, Volume: 473, Issue:11

    Topics: Acetyl Coenzyme A; Animals; Diabetes Mellitus, Type 2; Fatty Acids; Glucose; Insulin Resistance; Magnetic Resonance Spectroscopy; Muscle, Skeletal; Myocardium; Oxidation-Reduction; Oxidoreductases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Rats; Rats, Sprague-Dawley

2021
Propofol ameliorates acute postoperative fatigue and promotes glucagon-regulated hepatic gluconeogenesis by activating CREB/PGC-1α and accelerating fatty acids beta-oxidation.
    Biochemical and biophysical research communications, 2022, 01-01, Volume: 586

    Topics: Acetyl Coenzyme A; Animals; Carnitine O-Palmitoyltransferase; CREB-Binding Protein; Fatigue; Fatty Acids, Nonesterified; Gene Expression Regulation; Gluconeogenesis; Hepatectomy; Hepatocytes; Hypnotics and Sedatives; Lipid Metabolism; Liver; Male; Oxidation-Reduction; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphoenolpyruvate; Phosphoenolpyruvate Carboxykinase (ATP); Postoperative Complications; Propofol; Pyruvic Acid; Rats; Rats, Sprague-Dawley

2022
A subset of synaptic transmission events is coupled to acetyl coenzyme A production.
    Journal of neurophysiology, 2022, 03-01, Volume: 127, Issue:3

    Topics: Acetates; Acetyl Coenzyme A; Animals; Glucose; Glutamic Acid; Mice; Oxidoreductases; Pyruvic Acid; Synaptic Transmission

2022
Comprehensively understanding metabolic pathways of protein during the anaerobic digestion of waste activated sludge.
    Chemosphere, 2022, Volume: 297

    Topics: Acetyl Coenzyme A; Alanine; Amino Acids; Anaerobiosis; Arginine; Glutamates; Glycine; Histidine; Leucine; Lysine; Metabolic Networks and Pathways; Methionine; Phenylalanine; Pyruvic Acid; Serine; Sewage; Threonine; Tyrosine

2022
Analysis of the Formation of Characteristic Aroma Compounds by Amino Acid Metabolic Pathways during Fermentation with
    Molecules (Basel, Switzerland), 2023, Mar-30, Volume: 28, Issue:7

    Topics: Acetyl Coenzyme A; Amino Acids; Fermentation; Metabolic Networks and Pathways; Odorants; Pyruvic Acid; Saccharomyces cerevisiae; Wine

2023