Page last updated: 2024-08-17

acetyl coenzyme a and mevalonic acid

acetyl coenzyme a has been researched along with mevalonic acid in 63 studies

Research

Studies (63)

TimeframeStudies, this research(%)All Research%
pre-199026 (41.27)18.7374
1990's6 (9.52)18.2507
2000's6 (9.52)29.6817
2010's18 (28.57)24.3611
2020's7 (11.11)2.80

Authors

AuthorsStudies
Endo, A; Kuroda, M1
Cornforth, J1
Amundson, CH; Bernstein, BA; Richardson, T1
Carter, WJ; Faas, FH; Wynn, JO1
Katsuki, H; Shimizu, I1
Bach, TJ; Boronat, A; Caelles, C; Ferrer, A; Weber, T; Wettstein, A1
Denisenko, TV; Dizhe, EB; Klimov, AN; Poliakova, ED; Vasil'eva, LE1
Kumagai, H; Omura, S; Tanaka, H; Tomoda, H1
Ekiel, I; Smith, IC; Sprott, GD1
Farnsworth, DE; Feyereisen, R1
Bortz, WM1
Ness, GC; Porter, JW; Qureshi, N; Slakey, LL1
Brown, MS; Dietschy, JM1
Hatanaka, H; Katsuki, H; Nagai, J; Shimizu, I1
Schimke, RT1
Higgins, MJ; Kekwick, RG1
Barth, C; Decker, K1
Awaya, J; Kesado, T; Omura, S; Ono, T1
Goodwin, CD; Margolis, S1
Denisenko, TV; Dizhe, EB; Klimova, TA; Poliakova, ED; Vasil'eva, LE2
Lachance, PA; Ott, DB1
Brunengraber, H; Endemann, G; Kopito, RR; Marinier, E; Murray, DM; Tomera, JF; Weinstock, SB1
Dizhe, EB; Klimov, AN; Klimova, TA; Poliakova, ED; Vasil'eva, LE1
Brunengraber, H; Kopito, RR; Murray, DM; Story, DL1
Fears, R1
Croteau, R; McCaskill, D2
Horbach, S; Sahm, H; Welle, R1
Bach, TJ; Disch, A; Hemmerlin, A; Rohmer, M1
Arigoni, D; Bacher, A; Eisenreich, W; Fuchs, G; Rieder, C; Strauss, G1
Burgner, JW; Hedl, M; Rodwell, VW; Sanchez-Neri, B; Stauffacher, CV; Sutherlin, A1
Berry, A; Hümbelin, M; Jore, J; Li, J; Lin, J; Thomas, A1
HENRIKSON, CV; SMITH, PF1
Rodwell, VW; Sutherlin, A1
Møller, K; Nielsen, J; Seker, T1
Cerdá-Olmedo, E; Domenech, C; Kuzina, V1
Hiruma, K; Itoyama, K; Kaneko, Y; Kinjoh, T; Mita, K; Shinoda, T1
Chen, F; Chen, J; Du, G; Liu, L; Shi, Z; Zhou, J1
Bowie, JU; Eisenberg, D; Korman, TP; Li, D; Sahachartsiri, B; Vinokur, JM1
Gu, J; Guo, F; Lu, W; Lv, X; Xie, W; Ye, L; Yu, H1
Baidoo, EE; Denby, CM; Keasling, JD; Rodriguez, S; Van Vu, T; Wang, G1
Banno, S; Matsuda, F; Shimizu, H; Toya, Y; Wada, K; Yoshikawa, K1
Lv, X; Wang, F; Xie, W; Xu, H; Ye, L; Yu, H; Zhou, P1
Cui, JY; Cui, LY; Guan, CG; Liang, WF; Wang, TM; Xing, XH; Yang, S; Yu, KW; Zhang, C1
Chen, Y; Ferreira, R; Nielsen, J; Siewers, V; Tippmann, S1
Allmann, S; Bertiaux, E; Biran, M; Bouyssou, G; Bringaud, F; Crouzols, A; Dittrich-Domergue, F; Fouillen, L; Kiema, TR; Mazet, M; Millerioux, Y; Moreau, P; Plazolles, N; Rotureau, B; Thapa, C; Wierenga, RK1
Li, Y; Liang, Q; Luan, Y; Qi, Q; Sun, Z; Wang, J; Wang, Q; Xu, J1
Kamata, K; Shimizu, H; Toya, Y1
Brachfeld, AC; Febvre, HP; Hulko, T; Liman, GLS; Santangelo, TJ1
Chen, Y; Ding, M; Li, B; Liu, H; Liu, M; Qu, J; Wang, Y; Xiao, W; Yao, M; Yuan, Y1
Guo, XJ; Jia, B; Liu, D; Liu, H; Qi, H; Yuan, YJ; Zhang, JL1
Fan, J; Li, C; Liu, H; Wang, C; Zhou, X1
Aki, T; Nakashimada, Y; Okamura, Y; Perez, CMT; Watanabe, K1
Lupette, J; Maréchal, E1
Cho, S; Kim, H; Lee, J; Na, JG; Son, JH; Yang, J; Yeon, YJ1
Antony, VB; Barnes, S; Berryhill, TF; Cai, GQ; Carter, AB; Davis, D; Ding, Q; Gu, L; Hanumanthu, VS; He, C; Hohl, RJ; Larson-Casey, JL; Longhini, ALF; Neighbors, JD; Surolia, R; Vaid, M; Wilson, LS; Yoder, BK; Zimmerman, KA1
Braun, LC; Findeisen, HM; Godfrey, R; Kahles, F; Klotz, L; Lagache, SMM; Liebmann, M; Sohrabi, Y; Sonntag, GVH; Waltenberger, J1
Hua, Q; Liu, SC; Liu, Z; Wei, LJ1
Huang, H; Li, ZJ; Shi, TQ; Sun, XM; Wang, LR; Wang, YZ1
Avalos, JL; Chen, JM; Dugar, D; Ip, SS; Wegner, SA; Zhang, Y1
Augustyniak, J; Bernat, P; Bratek-Gerej, E; Gawarecka, K; Janik, A; Kruszewska, JS; Palamarczyk, G; Perlińska-Lenart, U; Piłsyk, S; Skalmowska, P; Swiezewska, E1
Kang, MK; Kim, SW; Li, R; Liu, Q; Shao, X; Wang, C; Wang, Y; Wei, G; Zhou, S; Zhu, L1

Reviews

7 review(s) available for acetyl coenzyme a and mevalonic acid

ArticleYear
On the control of cholesterol synthesis.
    Metabolism: clinical and experimental, 1973, Volume: 22, Issue:12

    Topics: Acetyl Coenzyme A; Age Factors; Alcohol Oxidoreductases; Animals; Anticholesteremic Agents; Bile Acids and Salts; Carbon Radioisotopes; Cholesterol; Cholesterol, Dietary; Circadian Rhythm; Coenzyme A; Ethanol; Fasting; Fatty Acids, Nonesterified; Feedback; Female; Glutarates; Haplorhini; Homeostasis; Hormones; Humans; Intestine, Small; Liver; Male; Mevalonic Acid; Mice; Radiation Effects; Rats; Sex Factors

1973
Control of enzyme levels in mammalian tissues.
    Advances in enzymology and related areas of molecular biology, 1973, Volume: 37

    Topics: Acetyl Coenzyme A; Alcohol Oxidoreductases; Animals; Arginase; Catalase; Endoplasmic Reticulum; Enzymes; Genetics; Glutarates; Hormones; Humans; Kinetics; Ligases; Liver; Mammals; Mathematics; Methods; Mevalonic Acid; Molecular Biology; Oxygenases; Porphobilinogen Synthase; Protein Biosynthesis; Tetrahydrofolate Dehydrogenase

1973
Compartmentation of the early steps of cholesterol biosynthesis in mammalian liver.
    Molecular and cellular biochemistry, 1973, Dec-15, Volume: 2, Issue:2

    Topics: Acetates; Acetyl Coenzyme A; Acetyltransferases; Animals; ATP Citrate (pro-S)-Lyase; Carbon Radioisotopes; Cholesterol; Citrate (si)-Synthase; Citrates; Coenzyme A Ligases; Cytosol; Fatty Acids; Glutarates; Kinetics; Kynurenic Acid; Liver; Malate Dehydrogenase; Male; Mevalonic Acid; Mitochondria, Liver; Models, Biological; Organ Specificity; Perfusion; Rats; Tritium

1973
Biochemical controls of liver cholesterol biosynthesis.
    The American journal of clinical nutrition, 1981, Volume: 34, Issue:10

    Topics: Acetates; Acetyl Coenzyme A; Acyl Coenzyme A; Allosteric Regulation; Animals; Bile Acids and Salts; Cells, Cultured; Cholesterol; Cholesterol, Dietary; Circadian Rhythm; Diet; Diphosphates; Enterohepatic Circulation; Fasting; Feedback; Female; Food; Humans; Hydroxymethylglutaryl CoA Reductases; Lipoproteins, LDL; Liver; Male; Meglutol; Mevalonic Acid; Rats; Receptors, Cell Surface; Receptors, LDL; Squalene; Tretinoin

1981
The contribution of the cholesterol biosynthetic pathway to intermediary metabolism and cell function.
    The Biochemical journal, 1981, Oct-01, Volume: 199, Issue:1

    Topics: Acetyl Coenzyme A; Adenine; Animals; Cells; Cholesterol; Dolichols; Humans; Hydroxymethylglutaryl CoA Reductases; Isopentenyladenosine; Lipoproteins; Mevalonic Acid; Rats; Ubiquinone

1981
Relationship between acyl-lipid and sterol metabolisms in diatoms.
    Biochimie, 2020, Volume: 169

    Topics: Acetyl Coenzyme A; Algal Proteins; Carbon; Diatoms; Endoplasmic Reticulum; Fatty Acids, Unsaturated; Lipid Metabolism; Mevalonic Acid; Multienzyme Complexes; Palmitic Acid; Plastids; Sterols; Triglycerides

2020
Advanced Strategies for the Synthesis of Terpenoids in
    Journal of agricultural and food chemistry, 2021, Mar-03, Volume: 69, Issue:8

    Topics: Acetyl Coenzyme A; Metabolic Engineering; Mevalonic Acid; Terpenes; Yarrowia

2021

Other Studies

56 other study(ies) available for acetyl coenzyme a and mevalonic acid

ArticleYear
Inhibition of in vitro cholesterol synthesis by fatty acids.
    Biochimica et biophysica acta, 1976, Jan-18, Volume: 486, Issue:1

    Topics: Acetates; Acetyl Coenzyme A; Acetyl-CoA C-Acetyltransferase; Animals; Cholesterol; Depression, Chemical; Fatty Acids; Fatty Acids, Unsaturated; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Synthase; Male; Mevalonic Acid; Microsomes, Liver; Phytanic Acid; Rats; Structure-Activity Relationship

1976
Symmetry of squalene epoxidation in vivo.
    Proceedings of the Royal Society of London. Series B, Biological sciences, 1977, Nov-14, Volume: 199, Issue:1135

    Topics: Acetyl Coenzyme A; Animals; Cholesterol; Epoxy Compounds; Farnesol; Lanosterol; Liver; Mevalonic Acid; Rats; Squalene

1977
Inhibition of cholesterol biosynthesis and acetyl-coenzyme A synthetase by bovine milk and orotic acid.
    Journal of dairy science, 1977, Volume: 60, Issue:12

    Topics: Acetate-CoA Ligase; Acetates; Acetyl Coenzyme A; Animals; Cattle; Cholesterol; Coenzyme A Ligases; Hydroxymethylglutaryl CoA Reductases; Kinetics; Liver; Mevalonic Acid; Milk; Nicotinic Acids; Orotic Acid; Rats; Saccharomyces cerevisiae

1977
Unsaturated fatty acyl-CoA inhibition of cholesterol synthesis in vitro.
    Biochimica et biophysica acta, 1977, May-25, Volume: 487, Issue:2

    Topics: Acetates; Acetyl Coenzyme A; Animals; Cholesterol; Coenzyme A; Cytosol; Digitonin; Fatty Acids; Fatty Acids, Unsaturated; Liver; Male; Mevalonic Acid; Rats; Sterols; Thyroxine

1977
Effect of temperature on ergosterol biosynthesis in yeast.
    Journal of biochemistry, 1975, Volume: 77, Issue:5

    Topics: Acetyl Coenzyme A; Ergosterol; Lipids; Methyltransferases; Mevalonic Acid; Oxygen; Saccharomyces cerevisiae; Squalene; Sterols; Temperature

1975
Aspects related to mevalonate biosynthesis in plants.
    Lipids, 1991, Volume: 26, Issue:8

    Topics: Acetyl Coenzyme A; Acetyl-CoA C-Acetyltransferase; Acyl Coenzyme A; Amino Acid Sequence; DNA; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Synthase; Mevalonic Acid; Molecular Sequence Data; Oxo-Acid-Lyases; Plants

1991
[Formation of mevalonic acid, sterols and bile acids from [1-14C]acetyl-CoA and [2-14C]malonyl-CoA in the liver of rabbits with experimental hypercholesterolemia].
    Biokhimiia (Moscow, Russia), 1987, Volume: 52, Issue:2

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Animals; Bile Acids and Salts; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent; Hypercholesterolemia; Liver; Malonyl Coenzyme A; Mevalonic Acid; Rabbits; Sterols; Substrate Specificity

1987
F-244 specifically inhibits 3-hydroxy-3-methylglutaryl coenzyme A synthase.
    Biochimica et biophysica acta, 1987, Dec-14, Volume: 922, Issue:3

    Topics: Acetates; Acetic Acid; Acetyl Coenzyme A; Acetyl-CoA C-Acetyltransferase; Animals; Carbohydrate Sequence; Cell Line; Fatty Acids, Unsaturated; Hydroxymethylglutaryl-CoA Synthase; Lactones; Liver; Lovastatin; Mevalonic Acid; Oxo-Acid-Lyases; Rats; Sterols

1987
Mevalonic acid is partially synthesized from amino acids in Halobacterium cutirubrum: a 13C nuclear magnetic resonance study.
    Journal of bacteriology, 1986, Volume: 166, Issue:2

    Topics: Acetates; Acetic Acid; Acetyl Coenzyme A; Amino Acids; Glycerol; Halobacterium; Lipid Metabolism; Magnetic Resonance Spectroscopy; Mevalonic Acid; Models, Molecular

1986
Precursor supply for insect juvenile hormone III biosynthesis in a cockroach.
    The Journal of biological chemistry, 1987, Feb-25, Volume: 262, Issue:6

    Topics: Acetyl Coenzyme A; Animals; Cockroaches; Cycloheximide; Glucose; Leucine; Mathematics; Mevalonic Acid; Sesquiterpenes; Trehalose

1987
Occurrence of the enzymes effecting the conversion of acetyl CoA to squalene in homogenates of hog aorta.
    Journal of lipid research, 1973, Volume: 14, Issue:4

    Topics: Acetyl Coenzyme A; Alcohol Oxidoreductases; Alkenes; Animals; Aorta; Carbon Isotopes; Chromatography, DEAE-Cellulose; Chromatography, Gas; Chromatography, Paper; Coenzyme A; Farnesol; Glutarates; Hemiterpenes; Ligases; Mevalonic Acid; Multienzyme Complexes; Muscle, Smooth; Organophosphorus Compounds; Phosphoric Acids; Squalene; Subcellular Fractions; Swine

1973
Effect of alterations of the specific activity of the intracellular acetyl CoA pool on apparent rates of hepatic cholesterogenesis.
    Journal of lipid research, 1974, Volume: 15, Issue:5

    Topics: Acetates; Acetyl Coenzyme A; Alcohol Oxidoreductases; Animals; Caprylates; Carbon Dioxide; Carbon Radioisotopes; Catheterization; Cholesterol; Cholesterol, Dietary; Cholestyramine Resin; Coenzyme A; Cytosol; Diet; Female; Liver; Mevalonic Acid; Microsomes, Liver; Mitochondria, Liver; Organ Size; Rats; Stomach

1974
Mevalonate synthesis in the mitochondria of yeast.
    Biochimica et biophysica acta, 1973, Feb-14, Volume: 296, Issue:2

    Topics: Acetates; Acetyl Coenzyme A; Acetyltransferases; Aerobiosis; Alcohol Oxidoreductases; Carbon Isotopes; Cell Nucleus; Coenzyme A; Cytoplasm; Ergosterol; Glucosephosphate Dehydrogenase; Glutarates; Lipids; Mevalonic Acid; Microsomes; Mitochondria; Saccharomyces cerevisiae; Spheroplasts; Succinate Dehydrogenase

1973
An investigation into the role of malonyl-coenzyme A in isoprenoid biosynthesis.
    The Biochemical journal, 1973, Volume: 134, Issue:1

    Topics: Acetyl Coenzyme A; Animals; Bicarbonates; Carbon Isotopes; Carboxy-Lyases; Cell-Free System; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Paper; Coenzyme A; Columbidae; Ergosterol; Glutarates; Lipids; Liver; Malonates; Mevalonic Acid; Plants; Rats; Saccharomyces cerevisiae; Terpenes; Time Factors

1973
Target of inhibition by the anti-lipogenic antibiotic cerulenin of sterol synthesis in yeast.
    Biochemical and biophysical research communications, 1974, Apr-23, Volume: 57, Issue:4

    Topics: Acetoacetates; Acetyl Coenzyme A; Acetyltransferases; Antifungal Agents; Carbon Radioisotopes; Cell-Free System; Coenzyme A; Ethers, Cyclic; Fatty Acids, Unsaturated; Glutarates; Mevalonic Acid; Oxo-Acid-Lyases; Phytosterols; Saccharomyces cerevisiae; Spectrophotometry, Ultraviolet; Time Factors

1974
Specific activation of in vitro cholesterol biosynthesis by preincubation of rat liver homogenates.
    The Journal of biological chemistry, 1973, Nov-10, Volume: 248, Issue:21

    Topics: Acetates; Acetoacetates; Acetyl Coenzyme A; Animals; Carbon Dioxide; Carbon Radioisotopes; Cholesterol; Citrates; Cytosol; Enzyme Activation; Fatty Acids; Lipids; Liver; Magnesium; Male; Mevalonic Acid; Microsomes; Osmolar Concentration; Rats; Subcellular Fractions

1973
[Activities of 3-hydroxy-3-methylglutaryl-CoA reductase and acetyl-CoA carboxylase and rate of biosynthesis of mevalonic acid, squalene, sterols and fatty acids from [1-14C]acetyl-CoA and [2-14C]malonyl-CoA in rat liver: changes induced by daily rhythm].
    Biokhimiia (Moscow, Russia), 1981, Volume: 46, Issue:1

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Animals; Carbon Radioisotopes; Circadian Rhythm; Fatty Acids; Hydroxymethylglutaryl CoA Reductases; Kinetics; Ligases; Liver; Male; Malonyl Coenzyme A; Mevalonic Acid; Radioisotope Dilution Technique; Rats; Squalene; Sterols

1981
[Activities of 3-hydroxyl-3-methylglutaryl-CoA reductase and acetyl-CoA carboxylase and the rate of mevalonic acid, squalene, sterol and fatty acid biosynthesis from [1-14C]acetyl-CoA and [2-14C]malonyl-CoA in rat liver: effects of Triton WR 1339, starvat
    Biokhimiia (Moscow, Russia), 1981, Volume: 46, Issue:2

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Animals; Fatty Acids; Humans; Hydroxymethylglutaryl CoA Reductases; Kinetics; Ligases; Liver; Malonyl Coenzyme A; Mevalonic Acid; Polyethylene Glycols; Rats; Squalene; Starvation; Sterols

1981
The shunt pathway of mevalonate metabolism in the isolated perfused rat liver.
    The Journal of biological chemistry, 1984, Jul-25, Volume: 259, Issue:14

    Topics: Acetyl Coenzyme A; Animals; Carbon Dioxide; Carbon Radioisotopes; Female; Liver; Male; Mevalonic Acid; Perfusion; Rats; Rats, Inbred Strains

1984
[Biosynthesis of mevalonic acid, sterols and bile acids from acetyl-CoA and malonyl-CoA in the human liver].
    Biokhimiia (Moscow, Russia), 1983, Volume: 48, Issue:11

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Bile Acids and Salts; Carbon Radioisotopes; Humans; Kinetics; Liver; Malonyl Coenzyme A; Mevalonic Acid; Sterols

1983
The shunt pathway of mevalonate metabolism in the isolated perfused rat kidney.
    The Journal of biological chemistry, 1984, Jan-10, Volume: 259, Issue:1

    Topics: Acetyl Coenzyme A; Animals; Female; Kidney; Male; Mevalonic Acid; Models, Biological; Perfusion; Rats; Rats, Inbred Strains; Sex Characteristics

1984
Isoprenoid synthesis in peppermint (Mentha x piperita): development of a model system for measuring flux of intermediates through the mevalonic acid pathway in plants.
    Biochemical Society transactions, 1995, Volume: 23, Issue:2

    Topics: Acetyl Coenzyme A; Carbon Radioisotopes; Homeostasis; Mevalonic Acid; Models, Biological; Plants; Pyruvates; Radioisotope Dilution Technique; Terpenes

1995
Procedures for the isolation and quantification of the intermediates of the mevalonic acid pathway.
    Analytical biochemistry, 1993, Nov-15, Volume: 215, Issue:1

    Topics: Acetyl Coenzyme A; Carbon Radioisotopes; Cells, Cultured; Chemistry Techniques, Analytical; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Mevalonic Acid; Plant Cells; Plants; Polyisoprenyl Phosphates; Reference Standards; Tritium; Urea

1993
Isoprenoid biosynthesis in bacteria: two different pathways?
    FEMS microbiology letters, 1993, Aug-01, Volume: 111, Issue:2-3

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Bacteria; Escherichia coli; Halobacterium; Hemiterpenes; Lactobacillus; Mevalonic Acid; Myxococcus; Organophosphorus Compounds; Species Specificity; Staphylococcus; Terpenes; Zymomonas

1993
Mevalonate-derived isopentenyl diphosphate is the biosynthetic precursor of ubiquinone prenyl side chain in tobacco BY-2 cells.
    The Biochemical journal, 1998, Apr-15, Volume: 331 ( Pt 2)

    Topics: Acetyl Coenzyme A; Carbon Isotopes; Cell Line; Coenzymes; Glucose; Glyceraldehyde 3-Phosphate; Hemiterpenes; Mevalonic Acid; Mitochondria; Nicotiana; Organophosphorus Compounds; Plants, Toxic; Plastoquinone; Polyisoprenyl Phosphates; Pyruvic Acid; Sterols; Ubiquinone

1998
Biosynthesis of the diterpene verrucosan-2beta-ol in the phototrophic eubacterium Chloroflexus aurantiacus. A retrobiosynthetic NMR study.
    The Journal of biological chemistry, 1998, Jul-17, Volume: 273, Issue:29

    Topics: Acetyl Coenzyme A; Chlorobi; Diterpenes; Glyceraldehyde 3-Phosphate; Magnetic Resonance Spectroscopy; Mevalonic Acid; Models, Chemical; Pyruvic Acid; Xylulose

1998
Enterococcus faecalis 3-hydroxy-3-methylglutaryl coenzyme A synthase, an enzyme of isopentenyl diphosphate biosynthesis.
    Journal of bacteriology, 2002, Volume: 184, Issue:15

    Topics: Acetyl Coenzyme A; Amino Acid Sequence; Animals; Antigens, Bacterial; Coenzyme A Ligases; Enterococcus faecalis; Escherichia coli; Genetic Vectors; Hemiterpenes; Hydrogen-Ion Concentration; Hydroxymethylglutaryl-CoA Synthase; Kinetics; Magnesium Chloride; Mevalonic Acid; Molecular Sequence Data; Molecular Weight; Organophosphorus Compounds; Recombinant Proteins; Temperature

2002
Genetics of isoprenoid biosynthesis in Paracoccus zeaxanthinifaciens.
    Gene, 2002, Sep-04, Volume: 297, Issue:1-2

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Amino Acid Sequence; Bacterial Proteins; Carbon-Carbon Double Bond Isomerases; DNA, Bacterial; Hemiterpenes; Hydroxymethylglutaryl CoA Reductases; Membrane Proteins; Mevalonic Acid; Molecular Sequence Data; Organophosphorus Compounds; Paracoccus; Polyisoprenyl Phosphates; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Sesquiterpenes; Terpenes

2002
COMPARATIVE BIOSYNTHESIS OF MEVALONIC ACID BY MYCOPLASMA.
    Journal of bacteriology, 1965, Volume: 89

    Topics: Acetates; Acetyl Coenzyme A; Acetyl-CoA C-Acyltransferase; Amides; Carbon Isotopes; Carotenoids; Coenzyme A; Fatty Acids; Iodoacetates; Lipid Metabolism; Metabolism; Mevalonic Acid; Mycoplasma; NADP; Oxidoreductases; Phosphotransferases; Research; Terpenes

1965
Multienzyme mevalonate pathway bioreactor.
    Biotechnology and bioengineering, 2004, Aug-20, Volume: 87, Issue:4

    Topics: Acetyl Coenzyme A; Acetyl-CoA C-Acetyltransferase; Bioreactors; Enterococcus faecalis; Enzyme Activation; Enzymes, Immobilized; Hemiterpenes; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Synthase; Kinetics; Mevalonic Acid; Multienzyme Complexes; Organophosphorus Compounds; Recombinant Proteins

2004
Analysis of acyl CoA ester intermediates of the mevalonate pathway in Saccharomyces cerevisiae.
    Applied microbiology and biotechnology, 2005, Volume: 67, Issue:1

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Ethanol; Galactose; Glucose; Mevalonic Acid; Saccharomyces cerevisiae

2005
Relationships among the biosyntheses of ubiquinone, carotene, sterols, and triacylglycerols in Zygomycetes.
    Archives of microbiology, 2006, Volume: 186, Issue:6

    Topics: Acetyl Coenzyme A; beta Carotene; Carbon Radioisotopes; Ergosterol; Leucine; Mevalonic Acid; Mucorales; Multivariate Analysis; Phycomyces; Triglycerides; Ubiquinone

2006
Control of juvenile hormone biosynthesis in Bombyx mori: cloning of the enzymes in the mevalonate pathway and assessment of their developmental expression in the corpora allata.
    Insect biochemistry and molecular biology, 2007, Volume: 37, Issue:8

    Topics: Acetyl Coenzyme A; Animals; Bombyx; Cloning, Molecular; Corpora Allata; Female; Gene Expression Regulation, Developmental; Geranyltranstransferase; Insect Proteins; Juvenile Hormones; Larva; Male; Mevalonic Acid; Phylogeny; Polyisoprenyl Phosphates; RNA, Messenger; Sesquiterpenes

2007
[Effect of acetyl-CoA synthase gene overexpression on physiological function of Saccharomyces cerevisiae].
    Wei sheng wu xue bao = Acta microbiologica Sinica, 2010, Volume: 50, Issue:9

    Topics: Acetyl Coenzyme A; Ethanol; Gene Expression Regulation, Fungal; Mevalonic Acid; Saccharomyces cerevisiae; Signal Transduction

2010
A synthetic biochemistry system for the in vitro production of isoprene from glycolysis intermediates.
    Protein science : a publication of the Protein Society, 2014, Volume: 23, Issue:5

    Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Biosynthetic Pathways; Butadienes; Escherichia coli; Glycolysis; Green Chemistry Technology; Hemiterpenes; Metabolic Engineering; Mevalonic Acid; NADP; Pentanes; Phosphoenolpyruvate; Pyruvic Acid

2014
Enhanced isoprene biosynthesis in Saccharomyces cerevisiae by engineering of the native acetyl-CoA and mevalonic acid pathways with a push-pull-restrain strategy.
    Journal of biotechnology, 2014, Sep-30, Volume: 186

    Topics: Acetyl Coenzyme A; Butadienes; Galactose; Hemiterpenes; Hydroxymethylglutaryl CoA Reductases; Metabolic Engineering; Metabolic Networks and Pathways; Mevalonic Acid; Oxygen; Pentanes; Saccharomyces cerevisiae

2014
ATP citrate lyase mediated cytosolic acetyl-CoA biosynthesis increases mevalonate production in Saccharomyces cerevisiae.
    Microbial cell factories, 2016, Mar-03, Volume: 15

    Topics: Acetyl Coenzyme A; ATP Citrate (pro-S)-Lyase; Cytosol; Intracellular Space; Metabolic Networks and Pathways; Mevalonic Acid; Nitrogen; Protein Engineering; Saccharomyces cerevisiae; Time Factors

2016
    Journal of bioscience and bioengineering, 2017, Volume: 123, Issue:2

    Topics: Acetyl Coenzyme A; Biomass; Carbon Isotopes; Enterococcus faecalis; Escherichia coli; Glucose; Metabolic Flux Analysis; Mevalonic Acid; NADP; Organisms, Genetically Modified; Oxidation-Reduction; Pentose Phosphate Pathway

2017
Dual regulation of cytoplasmic and mitochondrial acetyl-CoA utilization for improved isoprene production in Saccharomyces cerevisiae.
    Nature communications, 2016, 09-21, Volume: 7

    Topics: Acetyl Coenzyme A; Butadienes; Cytoplasm; Gene Expression Regulation, Fungal; Hemiterpenes; Metabolic Engineering; Metabolic Networks and Pathways; Mevalonic Acid; Mitochondria; Pentanes; Saccharomyces cerevisiae

2016
Biosensor-assisted transcriptional regulator engineering for Methylobacterium extorquens AM1 to improve mevalonate synthesis by increasing the acetyl-CoA supply.
    Metabolic engineering, 2017, Volume: 39

    Topics: Acetyl Coenzyme A; Biosensing Techniques; Biosynthetic Pathways; Carbon Cycle; Gene Expression Regulation; Genetic Enhancement; Metabolic Engineering; Metabolic Networks and Pathways; Methylobacterium extorquens; Mevalonic Acid; Transcription, Genetic; Transcriptional Activation; Up-Regulation

2017
Effects of acetoacetyl-CoA synthase expression on production of farnesene in Saccharomyces cerevisiae.
    Journal of industrial microbiology & biotechnology, 2017, Volume: 44, Issue:6

    Topics: Acetyl Coenzyme A; Acetyl-CoA C-Acetyltransferase; Acyl Coenzyme A; Coenzyme A Ligases; Mevalonic Acid; Saccharomyces cerevisiae; Sesquiterpenes; Streptomyces

2017
De novo biosynthesis of sterols and fatty acids in the Trypanosoma brucei procyclic form: Carbon source preferences and metabolic flux redistributions.
    PLoS pathogens, 2018, Volume: 14, Issue:5

    Topics: Acetates; Acetyl Coenzyme A; Acetyltransferases; Acyl Coenzyme A; Alcohol Oxidoreductases; Animals; Carbon; Fatty Acids; Gene Expression Regulation; Gene Knockout Techniques; Glucose; Insect Vectors; Leucine; Mevalonic Acid; Proline; Sterols; Threonine; Trypanosoma brucei brucei; Tsetse Flies

2018
Engineering an in vivo EP-bifido pathway in Escherichia coli for high-yield acetyl-CoA generation with low CO
    Metabolic engineering, 2019, Volume: 51

    Topics: Acetyl Coenzyme A; Carbon Dioxide; Escherichia coli; Fatty Acids; Fermentation; Glycolysis; Hydroxybutyrates; Metabolic Engineering; Metabolic Flux Analysis; Metabolic Networks and Pathways; Mevalonic Acid; NADP; Polyesters

2019
Effect of precise control of flux ratio between the glycolytic pathways on mevalonate production in Escherichia coli.
    Biotechnology and bioengineering, 2019, Volume: 116, Issue:5

    Topics: Acetyl Coenzyme A; Escherichia coli; Glucose; Glycolysis; Metabolic Flux Analysis; Mevalonic Acid; NADP; Pentose Phosphate Pathway

2019
A linear pathway for mevalonate production supports growth of Thermococcus kodakarensis.
    Extremophiles : life under extreme conditions, 2019, Volume: 23, Issue:2

    Topics: Acetyl Coenzyme A; Hemiterpenes; Mevalonic Acid; Organophosphorus Compounds; Thermococcus

2019
Primary and Secondary Metabolic Effects of a Key Gene Deletion (Δ
    Applied and environmental microbiology, 2019, 04-01, Volume: 85, Issue:7

    Topics: Acetyl Coenzyme A; Aldehyde Oxidoreductases; DNA, Fungal; Fermentation; Galactose; Gene Deletion; Gene Expression Regulation, Fungal; Metabolic Engineering; Mevalonic Acid; Mitochondrial Membrane Transport Proteins; Mitochondrial Precursor Protein Import Complex Proteins; Promoter Regions, Genetic; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Secondary Metabolism; Sequence Analysis, RNA; Systems Biology; Terpenes

2019
Constructing Yeast Chimeric Pathways To Boost Lipophilic Terpene Synthesis.
    ACS synthetic biology, 2019, 04-19, Volume: 8, Issue:4

    Topics: Acetyl Coenzyme A; Lycopene; Mevalonic Acid; Saccharomyces cerevisiae; Terpenes; Transcription, Genetic; Up-Regulation; Yarrowia

2019
Enhanced β-Amyrin Synthesis in Saccharomyces cerevisiae by Coupling An Optimal Acetyl-CoA Supply Pathway.
    Journal of agricultural and food chemistry, 2019, Apr-03, Volume: 67, Issue:13

    Topics: Acetyl Coenzyme A; Cytosol; Fermentation; Metabolic Engineering; Mevalonic Acid; Oleanolic Acid; Saccharomyces cerevisiae

2019
Metabolite Profile Analysis of Aurantiochytrium limacinum SR21 Grown on Acetate-based Medium for Lipid Fermentation.
    Journal of oleo science, 2019, Jun-06, Volume: 68, Issue:6

    Topics: Acetates; Acetyl Coenzyme A; Culture Media; Fatty Acids; Fermentation; Glucaric Acid; Lipid Metabolism; Mevalonic Acid; NADP; Pentose Phosphate Pathway; Stramenopiles

2019
Mevalonate production from ethanol by direct conversion through acetyl-CoA using recombinant Pseudomonas putida, a novel biocatalyst for terpenoid production.
    Microbial cell factories, 2019, Oct-10, Volume: 18, Issue:1

    Topics: Acetyl Coenzyme A; Biofuels; Ethanol; Metabolic Engineering; Mevalonic Acid; Microorganisms, Genetically-Modified; Pseudomonas putida; Pyruvic Acid; Terpenes

2019
Increased flux through the mevalonate pathway mediates fibrotic repair without injury.
    The Journal of clinical investigation, 2019, 11-01, Volume: 129, Issue:11

    Topics: Acetyl Coenzyme A; Adolescent; Adult; Aged; Animals; Female; Humans; Idiopathic Pulmonary Fibrosis; Macrophages; Male; Mevalonic Acid; Mice; Mice, Knockout; Middle Aged; Neuropeptides; Oxidation-Reduction; rac1 GTP-Binding Protein

2019
LXR Activation Induces a Proinflammatory Trained Innate Immunity-Phenotype in Human Monocytes.
    Frontiers in immunology, 2020, Volume: 11

    Topics: Acetyl Coenzyme A; Cells, Cultured; Cellular Reprogramming; Epigenesis, Genetic; Humans; Immunity, Innate; Immunologic Memory; Inflammation; Interleukin-1beta; Liver X Receptors; Mevalonic Acid; Monocytes; Mycobacterium bovis; Phenotype; Signal Transduction

2020
Pathway engineering and medium optimization for α-farnesene biosynthesis in oleaginous yeast Yarrowia lipolytica.
    Journal of biotechnology, 2020, Aug-10, Volume: 319

    Topics: Acetyl Coenzyme A; Metabolic Engineering; Mevalonic Acid; Promoter Regions, Genetic; Sesquiterpenes; Yarrowia

2020
Engineering acetyl-CoA supply and ERG9 repression to enhance mevalonate production in Saccharomyces cerevisiae.
    Journal of industrial microbiology & biotechnology, 2021, Dec-23, Volume: 48, Issue:9-10

    Topics: Acetate-CoA Ligase; Acetyl Coenzyme A; Enterococcus faecalis; Metabolic Engineering; Mevalonic Acid; Microorganisms, Genetically-Modified; Saccharomyces cerevisiae; Salmonella enterica

2021
Synthesis of Dolichols in
    International journal of molecular sciences, 2021, Dec-30, Volume: 23, Issue:1

    Topics: Acetyl Coenzyme A; Amino Acid Sequence; Candida albicans; Dolichols; Fatty Acids; Fungal Proteins; Gene Expression Regulation, Fungal; Genes, Fungal; Humans; Hyphae; Mevalonic Acid; Mutation; Phylogeny; Polyprenols; RNA, Messenger; Saccharomyces cerevisiae; Substrate Specificity

2021
Reassessing acetyl-CoA supply and NADPH availability for mevalonate biosynthesis from glycerol in Escherichia coli.
    Biotechnology and bioengineering, 2022, Volume: 119, Issue:10

    Topics: Acetyl Coenzyme A; Escherichia coli; Glycerol; Metabolic Engineering; Mevalonic Acid; NADP; Terpenes

2022