Page last updated: 2024-08-17

acetyl coenzyme a and malonyl coenzyme a

acetyl coenzyme a has been researched along with malonyl coenzyme a in 181 studies

Research

Studies (181)

TimeframeStudies, this research(%)All Research%
pre-199064 (35.36)18.7374
1990's32 (17.68)18.2507
2000's37 (20.44)29.6817
2010's36 (19.89)24.3611
2020's12 (6.63)2.80

Authors

AuthorsStudies
Fitzgerald, V; Rock, CO; Snyder, F1
Rous, S1
Labadie, P1
Engeser, H; Lynen, F; Wieland, F1
Giompres, P; Packter, NM1
Ferrick, TJ; Ness, GC; Porter, JW; Slakey, LL1
Holland, R; Roughan, PG; Slack, CR1
Kishimoto, Y; Murad, S1
Kariya, T; Wille, LJ1
Dhopeshwarkar, GA; Elepano, MG; Mead, JF1
Kikuchi, S; Kolattukudy, PE1
Jordan, PM; Spencer, JB1
Kikuchi, S; Kolattukudy, PE; Rainwater, DL1
Dickson, AC; Koeppen, AH; Riley, KM1
Cronan, JE; Jackowski, S; Murphy, CM; Rock, CO1
Horie, S; Suga, T; Suzuki, T1
Fukuda, H; Iritani, N; Katsurada, A1
Claeys, A; De Spiegeleer, B; Mannens, G; Slegers, G; Van den Bossche, W1
Wakil, SJ1
Denisenko, TV; Dizhe, EB; Klimov, AN; Poliakova, ED; Vasil'eva, LE1
Buckley, MG; Rath, EA1
Nomura, G; Takamura, Y1
Gaucher, GM; Lam, KS; Neway, JO1
Ikai, A; Morishima, N1
Jackowski, S; Rock, CO1
Engel, AG; Zierz, S1
Aoyama, H; Nakatani, T; Sato, T; Siegel, JH; Vary, TC1
Gilbert, HF; Walters, DW1
Knudsen, J; Mikkelsen, J; Smith, S1
Højrup, P; Knudsen, J; Mikkelsen, J; Rasmussen, MM; Roepstorff, P1
Cassagne, C; Heape, MA; Sargueil-Boiron, F1
Arakawa, A; Kitayama, Y; Ogawa, Y; Takamura, Y; Tosaki, M; Yamanaka, S1
Anderson, VE; Hammes, GG1
Hansen, HF; Hansen, JK; Højrup, P; Knudsen, J; Mikkelsen, J1
Bar-Tana, J; Rose-Kahn, G1
Jilka, JM; Kazemi, M; Rahmatullah, M; Roche, TE1
Ohashi, K; Otsuka, H; Seyama, Y1
Linn, T; Smith, S; Stern, A1
Bird, MI; Edwards, MR; Saggerson, ED1
Knudsen, J; Mikkelsen, J; Smith, S; Stern, A1
Jones, CT; Wahle, KW1
Denisenko, TV; Dizhe, EB; Klimova, TA; Poliakova, ED; Vasil'eva, LE2
Inui, H; Kitaoka, S; Miyatake, K; Nakano, Y1
Foster, DW; McGarry, JD1
Cinti, DL; Cook, L; Prasad, MR; Vieth, R1
Brown, GK; Scholem, RD1
Koeppen, AH; Mitzen, EJ1
Tsao, MU1
Hardie, DG; McCarthy, AD1
McCormick, K; Notar-Francesco, VJ; Sriwatanakul, K1
Dizhe, EB; Klimov, AN; Klimova, TA; Poliakova, ED; Vasil'eva, LE1
Hsu, RY; Sheplock, GJ; Soulié, JM; Tian, WX1
Borrebaek, B; Bremer, J; Singh, B; Stakkestad, JA1
Ernst-Fonberg, ML; Jonak, ZL; Walker, TA; Worsham, LM1
Katiyar, SS; Pan, D; Porter, JW1
Arai, K; Kawaguchi, A; Koike, N; Okuda, S; Saito, Y; Seyama, Y; Yamakawa, T1
Benveniste, J; Mencia-Huerta, JM; Morgat, JL; Roubin, R1
Denisenko, TV; Dizhe, EB; Klimov, AN; Klimova, TA; Petrova, LA; Poliakova, ED; Vasil'eva, LE1
Kumar, S; Srinivasan, KR2
Linn, TC; Srere, PA; Stark, MJ1
Grunnet, I; Knudsen, J1
Arai, K; Kawaguchi, A; Okuda, S; Seyama, Y; Yamakawa, T1
Cinti, DL; Keyes, SR1
Kurosaki, F3
Corkey, BE; Curtiss, D; Kilpatrick, L; Nachiappan, V1
Heath, RJ; Rock, CO1
Gamble, J; Lopaschuk, GD1
Barr, A; Barr, R; Itoi, T; Lopaschuk, GD; Witters, LA1
Gulliver, BS; Slabas, AR1
Hutchinson, CR; Shen, B1
Cane, DE1
Aparicio, JF; Caffrey, P; Leadlay, PF; Loughran, MS; Marsden, AF; Staunton, J1
Ikai, A1
Falk, KL; Guerra, DJ1
Allard, MF; Lopaschuk, GD; Schönekess, BO1
Bhogal, P; Child, CJ; Shoolingin-Jordan, PM; Spencer, JB1
Rangan, VS; Smith, S2
Chohnan, S; Fujio, T; Furukawa, H; Nishihara, H; Takamura, Y1
Laugier, C; Pacheco, H; Pageaux, JF1
Roughan, PG1
Kawaguchi, A; Kondo, K; Watanabe, K; Yazawa, K1
Child, CJ; Shoolingin-Jordan, PM1
Katiyar, SS; Mukherjee, S1
Chohnan, S; Izawa, H; Nishihara, H; Takamura, Y1
Hunter, SC; Ohlrogge, JB1
An, JH; Kim, YS1
Joshi, AK; Rangan, VS; Smith, S1
Bauer, Z; Fuchs, G; Gad'on, N; Huber, H; Menendez, C; Stetter, KO1
Bowman, ME; Dixon, RA; Ferrer, JL; Jez, JM; Noel, JP1
Heigenhauser, GJ; Howlett, RA; Spriet, LL; Starritt, EC1
Kealey, JT; Khosla, C; Pohl, NL; Richardson, MT1
Kerr, RG; Wen, J1
Bartlett, K; Eaton, S; Fukumoto, K; Paladio Duran, N; Pierro, A; Quant, PA; Spitz, L1
Allard, MF; Barr, RL; Longnus, SL; Lopaschuk, GD; Wambolt, RB1
Florova, G; Kazanina, G; Reynolds, KA1
Bouchard, B; Brunengraber, H; Des Rosiers, C; Kelleher, JK; Poirier, M; Reszko, AE; Vincent, G1
Cane, DE; Khosla, C; Lau, J; Liou, GF1
Fuchs, G; Hügler, M; Jahn, M; Krieger, RS1
Fukuzawa, H; Kajikawa, M; Kanamaru, H; Ohyama, K; Sakuradani, E; Shimizu, S; Yamaoka, S; Yamato, KT1
Ahmed, S; Bassilian, S; Boren, J; Boros, LG; Cascante, M; Centelles, JJ; Lee, WN; Lim, S1
SAUER, F1
HUELSMANN, WC1
Schofield, CJ; Sleeman, MC1
Kelleher, NL; McLoughlin, SM; Tseng, CC; Walsh, CT1
Abe, I; Noguchi, H; Oguro, S; Utsumi, Y1
Glickman, JF; Weiss, DR1
Arrhenius, T; Barr, R; Brown, S; Chandler, MP; Cheng, JF; Dyck, JR; Harmon, C; Lopaschuk, GD; Nadzan, AM; Stanley, WC; Wallace, D; Yang, G1
Bartram, S; Falk, KL; Gershenzon, J; Hick, A; Pickett, JA; Textor, S; Vogel, C1
Brunengraber, H; Cheng, JF; David, F; Des Rosiers, C; Diaz, M; Dyck, JR; Jobbins, KA; Kasumov, T; Lopaschuk, GD; Reszko, AE; Stanley, WC; Thomas, KR1
Bederman, IR; Brunengraber, H; David, F; Kasumov, T; Kelleher, JK; Reszko, AE1
Halberg, N; Hillig, T; Kiens, B; Richter, EA; Roepstorff, C; Ruderman, NB; Saha, AK; Wojtaszewski, JF1
Astrup, AV; Buemann, B1
Brock, M; Keller, NP; Zhang, YQ1
Bian, F; Brunengraber, H; David, F; Hoppel, CL; Jobbins, KA; Kasumov, T; Minkler, PE; Thomas, KR1
Cheng, D; Rendina, AR1
Adams, JE; Bian, F; Brunengraber, H; David, F; Hoppel, CL; Jobbins, KA; Kasumov, T; Minkler, PE; Thomas, KR1
Griffin, MJ; Sul, HS1
Choi, CS; Cline, GW; Coleman, RA; Hammond, LE; Liu, ZX; Morino, K; Neschen, S; Pongratz, RL; Romanelli, AJ; Shulman, GI; Zhang, D; Zhang, XM1
Anderson, VE; Bian, F; Brunengraber, H; Hoppel, CL; Jobbins, KA; Kasumov, T; Kerner, J; Minkler, PE1
Hayashi, O; Satoh, K2
Onay-Besikci, A; Sambandam, N1
Amills, M; Ares, JL; Badaoui, B; Carrizosa, J; Jordana, J; Sànchez, A; Serradilla, JM; Tomàs, A; Urrutia, B1
Burns, DJ; Camp, HS; Cheng, X; Chiou, W; Gao, L; Tang, H1
Geders, TW; Gerwick, WH; Gu, L; Håkansson, K; Sherman, DH; Smith, JL; Wang, B1
Lantz, AE; Nielsen, J; Nielsen, ML; Wattanachaisaereekul, S1
Gao, X; Jiang, L; Li, S; Li, W; Liu, Y; Rui, L; Wang, J; Wang, Q; You, J; Yu, Y; Zeng, R1
Schink, B1
Chohnan, S; Hanada, S; Jackowski, S; Leonardi, R; Miyamoto, Y; Takagi, M; Tamaki, H1
Kharel, MK; Lian, H; Pahari, P; Rohr, J1
Chohnan, S; Katoh, H; Onizawa, N; Tokutake, Y; Toyoda, A1
Gilibili, RR; Giri, S; Kandaswamy, M; Mullangi, R; Rajagopal, S; Sharma, K1
Alves, J; Harris, JL; Peters, EC; Trauger, JW; Westling, L1
Fasano, M; Fischer, SK; Kudej, RK; Lewandowski, ED; Lopaschuk, GD; Vatner, DE; Vatner, SF; Zhao, X1
Brendel, N; Frank, S; Hertweck, C; Jensen, K; Kohlhaas, C; Moldenhauer, J; Niederkrüger, H; Oldiges, M; Piel, J; Pöplau, P; Townsend, CA; Vagstad, AL; Zimmermann, K1
Chohnan, S; Iio, W; Kohari, D; Ogata, Y; Onizawa, N; Tokutake, Y; Toyoda, A1
Jeya, M; Kim, TS; Kumar Tiwari, M; Lee, JK; Li, J; Zhao, H1
Basu, R; Clanachan, A; Gandhi, M; Kassiri, Z; Lopaschuk, GD; Mori, J; Oudit, GY; Zhabyeyev, P1
Chen, WN; Feng, H; Tang, X1
Galdieri, L; Vancura, A; Zhang, M1
Hoppel, CL; Kerner, J; Lesnefsky, EJ; Minkler, PE1
Davaapil, H; Gout, I; Tsuchiya, Y1
Lian, J; Zhao, H1
Avidan, O; Brandis, A; Pick, U; Rogachev, I1
Chung, SK; Hwang, IW; Kato, T; Makishima, Y; Park, EY; Park, S; Suzuki, T; Terzic, A1
Cui, W; Ji, M; Liang, Y; Ma, X; Tian, W1
Chohnan, S; Goto, T; Hagiya, Y; Kubota, Y; Toyoda, A1
Haque, ME; Liu, A; Wang, J; Wang, R; Xu, R1
Bi, S; Li, X; Ling, B; Liu, Y; Wang, Z1
Galdieri, L; Gatla, H; Vancura, A; Vancurova, I1
Bardou, F; Bazet Lyonnet, B; Diacovich, L; Gago, G; Gramajo, H; Lemassu, A; Quémard, A; Spina, L1
Kondo, A; Matsumoto, T; Tanaka, T1
Higuchi, Y; Maeda, Y; Suyama, A; Takegawa, K; Urushihara, M1
Crosby, J; Crump, MP; Jackson, DR; Milligan, JC; Mohammed, LY; Patel, AB; Shakya, G; Tsai, SC; Valentic, TR; Vasilakis, K; Wattana-Amorn, P1
Holloway, GP; Petrick, HL1
Bilodeau, M; Cassim, S; Dehbidi-Assadzadeh, L; Lapierre, P; Raymond, VA1
Abbas, A; Abd Rahim, MH; Campbell, L; Carter, D; Hasan, H; Montoya, A3
Chu, LL; Dhakal, D; Pandey, RP; Pokhrel, AR; Shrestha, A; Sohng, JK1
Altabe, S; Arabolaza, A; Comba, S; Gramajo, H; Labadie, GR; Recio-Balsells, AI; Sabatini, M; Takano, E1
Kang, MK; Kim, J; Kim, SU; Kwon, M; Lee, AR; Ro, DK1
Hirata, Y; Kishida, M; Kondo, A; Konishi, R; Matsumoto, T; Otomo, C; Ozaki, A; Takayama, S; Tanaka, T1
Belew, GD; Jones, JG; Macedo, MP; Oliveira, PJ; Rito, J; Silva, J; Tavares, L; Teixeira, J; Viegas, I1
David, F; Ferreira, R; Hedin, A; Nielsen, J; Sánchez, BJ; Siewers, V; Skrekas, C1
Christopher, BA; Deleye, Y; Ilkayeva, O; McGarrah, RW; Newgard, CB; Page, S; Walejko, JM; White, PJ; Zhang, GF1
Ejsing, CS; Martínez-Montañés, F; Topolska, M1
Marienhagen, J; Milke, L1
Gu, Y; Ma, J; Marsafari, M; Xu, P1
Huang, K; Li, X; Shi, X; Wang, J; Yang, G; Zhang, D; Zhou, X1
Fan, A; Li, SM; Wang, H; Yang, Y; Zhang, L; Zheng, L1
Ding, S; Dong, M; Duan, X; Fan, X; Liu, S; Pablo, CM; Peng, H; Wu, J; Zhou, J; Zhou, L; Zhuang, Q1
Czech, MP; DiMarzio, C; Friedline, RH; Gao, G; Han, X; He, W; Herman, MA; Ilkayeva, OR; Kelly, M; Kim, JK; Lifshitz, L; Min, K; Newgard, CB; Pan, M; Raymond, N; Rowland, L; Wetoska, N; Xie, J; Yenilmez, B; Zhang, GF1
Chen, X; Li, P; Shang, L; Wang, Y; Yao, H; Zeng, J; Zhang, X1
Bai, Z; Fu, Z; Li, Y; Lin, P; Liu, C; Liu, X; Yang, Y1
Karlstaedt, A; Lorenzi, PL; Martinez, SA; Tan, L1

Reviews

11 review(s) available for acetyl coenzyme a and malonyl coenzyme a

ArticleYear
The relationship between structure and function for and the regulation of the enzymes of fatty acid synthesis.
    Annals of the New York Academy of Sciences, 1986, Volume: 478

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Animals; Enzyme Activation; Fatty Acid Synthases; Fatty Acids; Ligases; Liver; Macromolecular Substances; Malonyl Coenzyme A; Structure-Activity Relationship

1986
Regulation of hepatic fatty acid oxidation and ketone body production.
    Annual review of biochemistry, 1980, Volume: 49

    Topics: Acetyl Coenzyme A; Adipose Tissue; Animals; Carnitine; Carnitine Acyltransferases; Fatty Acids; Fatty Acids, Nonesterified; Glucagon; Glycogen; Insulin; Ketone Bodies; Liver; Malonyl Coenzyme A; Meglutol; Models, Biological; Triglycerides

1980
The 1993 Merck Frosst Award. Acetyl-CoA carboxylase: an important regulator of fatty acid oxidation in the heart.
    Canadian journal of physiology and pharmacology, 1994, Volume: 72, Issue:10

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Animals; Carbohydrate Metabolism; Carnitine; Carnitine O-Palmitoyltransferase; Diabetes Mellitus; Down-Regulation; Fatty Acids; Humans; Malonyl Coenzyme A; Mitochondria, Heart; Myocardial Ischemia; Oxidation-Reduction

1994
[Fatty acid synthetase].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1993, Volume: 38, Issue:7

    Topics: Acetyl Coenzyme A; Animals; Chemical Phenomena; Chemistry, Physical; Fatty Acid Synthases; Fatty Acids; Macromolecular Substances; Malonyl Coenzyme A

1993
Carnitine palmitoyl transferase I and the control of myocardial beta-oxidation flux.
    Biochemical Society transactions, 2001, Volume: 29, Issue:Pt 2

    Topics: Acetyl Coenzyme A; Animals; Biological Transport; Carnitine O-Palmitoyltransferase; Humans; Isoenzymes; Kinetics; Malonyl Coenzyme A; Mitochondria, Heart; Myocardium; Oxidation-Reduction

2001
Insulin regulation of fatty acid synthase gene transcription: roles of USF and SREBP-1c.
    IUBMB life, 2004, Volume: 56, Issue:10

    Topics: Acetyl Coenzyme A; Animals; CCAAT-Enhancer-Binding Proteins; DNA-Binding Proteins; Fatty Acid Synthases; Gene Expression Regulation, Enzymologic; Glucose; Humans; Insulin; Malonyl Coenzyme A; Mice; Models, Biological; Palmitic Acid; Promoter Regions, Genetic; Protein Binding; Rats; RNA, Messenger; Sterol Regulatory Element Binding Protein 1; Time Factors; Transcription Factors; Transcription, Genetic; Upstream Stimulatory Factors

2004
Signalling functions of coenzyme A and its derivatives in mammalian cells.
    Biochemical Society transactions, 2014, Volume: 42, Issue:4

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Coenzyme A; Malonyl Coenzyme A; Mammals; Signal Transduction

2014
Recent advances in biosynthesis of fatty acids derived products in Saccharomyces cerevisiae via enhanced supply of precursor metabolites.
    Journal of industrial microbiology & biotechnology, 2015, Volume: 42, Issue:3

    Topics: Acetyl Coenzyme A; Fatty Acids; Fatty Acids, Nonesterified; Humans; Malonyl Coenzyme A; Metabolic Engineering; Saccharomyces cerevisiae

2015
Engineering metabolic pathways in Escherichia coli for constructing a "microbial chassis" for biochemical production.
    Bioresource technology, 2017, Volume: 245, Issue:Pt B

    Topics: Acetyl Coenzyme A; Escherichia coli; Malonyl Coenzyme A; Metabolic Engineering; Metabolic Networks and Pathways; Shikimic Acid

2017
Engineering intracellular malonyl-CoA availability in microbial hosts and its impact on polyketide and fatty acid synthesis.
    Applied microbiology and biotechnology, 2020, Volume: 104, Issue:14

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Biofuels; Directed Molecular Evolution; Fatty Acids; Intracellular Space; Malonyl Coenzyme A; Metabolic Engineering; Polyketides

2020
Synthetic biology, systems biology, and metabolic engineering of Yarrowia lipolytica toward a sustainable biorefinery platform.
    Journal of industrial microbiology & biotechnology, 2020, Volume: 47, Issue:9-10

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Fatty Acids; Lipids; Malonyl Coenzyme A; Metabolic Engineering; Polyketides; Synthetic Biology; Systems Biology; Terpenes; Yarrowia

2020

Other Studies

170 other study(ies) available for acetyl coenzyme a and malonyl coenzyme a

ArticleYear
Coupling of the biosynthesis of fatty acids and fatty alcohols.
    Archives of biochemistry and biophysics, 1978, Volume: 186, Issue:1

    Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Animals; Cell-Free System; Detergents; Fatty Acid Synthases; Fatty Alcohols; Harderian Gland; Lacrimal Apparatus; Malonyl Coenzyme A; Microsomes; NADP; Rabbits; Trypsin

1978
Possible contribution of [2-3H]malate and [2, 3-3h]succinate tritium to the same tritiated NADPH pool for participation in fatty acid synthesis.
    Biochimie, 1978, Volume: 60, Issue:2

    Topics: Acetates; Acetyl Coenzyme A; Animals; Fatty Acid Synthases; Fatty Acids; Hydroxybutyrates; Lactates; Liver; Malates; Male; Malonyl Coenzyme A; Mice; NADP; Succinates; Tritium

1978
[Microsomal biogenesis of fatty acids by condensation of carrier proteins and a multi-enzymatic complex].
    La Revue du praticien, 1978, Oct-21, Volume: 28, Issue:47

    Topics: Acetyl Coenzyme A; Acyl Carrier Protein; Alcohol Oxidoreductases; Enzyme Precursors; Fatty Acid Synthases; Fatty Acids; Keto Acids; Malonyl Coenzyme A; Microsomes; Models, Biological; NADP

1978
Localization of three non-thiol binding sites on polypeptide chain beta of yeast fatty acid synthetase.
    FEBS letters, 1977, Oct-01, Volume: 82, Issue:1

    Topics: Acetyl Coenzyme A; Binding Sites; Dithionitrobenzoic Acid; Fatty Acid Synthases; Macromolecular Substances; Malonyl Coenzyme A; Nitrobenzoates; Palmitoyl Coenzyme A; Saccharomyces cerevisiae

1977
Purification and properties of the polymeric fatty acid synthetase from a filamentous fungus.
    Biochimica et biophysica acta, 1978, May-25, Volume: 529, Issue:2

    Topics: Acetyl Coenzyme A; Aspergillus fumigatus; Cold Temperature; Fatty Acid Synthases; Kinetics; Malonyl Coenzyme A; Microscopy, Electron; Molecular Weight; Protein Conformation

1978
De novo fatty acid synthesis and fatty acid elongation catalyzed by subcellular fractions from hog and human aorta.
    Lipids, 1979, Volume: 14, Issue:5

    Topics: Acetyl Coenzyme A; Animals; Aorta; Coenzyme A; Fatty Acid Synthases; Fatty Acids; Humans; Malonyl Coenzyme A; Species Specificity; Subcellular Fractions; Swine

1979
On the control of long-chain-fatty acid synthesis in isolated intact spinach (Spinacia oleracea) chloroplasts.
    The Biochemical journal, 1979, Nov-15, Volume: 184, Issue:2

    Topics: Acetates; Acetyl Coenzyme A; Acyl Carrier Protein; Bicarbonates; Buffers; Chloroplasts; Fatty Acids; In Vitro Techniques; Kinetics; Malonyl Coenzyme A

1979
Chain elongation of fatty acid in brain: a comparison of mitochondrial and microsomal enzyme activities.
    Archives of biochemistry and biophysics, 1978, Jan-30, Volume: 185, Issue:2

    Topics: Acetyl Coenzyme A; Aging; Animals; Brain; Fatty Acid Synthases; Fatty Acids; Malonyl Coenzyme A; Mice; Mice, Quaking; Microsomes; Mitochondria; Mutation; Myelin Sheath; Rats

1978
Inhibition of fatty acid synthesis by RMI 14,514 (5-tetradecyloxy-2-furoic acid).
    Biochemical and biophysical research communications, 1978, Feb-28, Volume: 80, Issue:4

    Topics: Acetyl Coenzyme A; Animals; Carboxylic Acids; Fatty Acids; Furans; Kinetics; Liver; Male; Malonyl Coenzyme A; Rats

1978
Transformations of the polyunsaturated fatty acids in the brain.
    Advances in experimental medicine and biology, 1977, Volume: 83

    Topics: Acetyl Coenzyme A; Animals; Binding, Competitive; Brain; Fatty Acid Synthases; Fatty Acids, Unsaturated; Kinetics; Malonyl Coenzyme A; Microsomes; Mitochondria; Rats

1977
Immobilization of fatty acid synthetase from Mycobacterium smegmatis by radiation-induced polymerization.
    Agricultural and biological chemistry, 1990, Volume: 54, Issue:6

    Topics: Acetyl Coenzyme A; Chromatography, Gas; Cross-Linking Reagents; Enzyme Stability; Enzymes, Immobilized; Fatty Acid Synthases; Fluorescent Antibody Technique; Hydrogen-Ion Concentration; Malonyl Coenzyme A; Methacrylates; Mycobacterium; Polymers; Temperature

1990
Investigation of the mechanism and steric course of the reaction catalyzed by 6-methylsalicylic acid synthase from Penicillium patulum using (R)-[1-13C;2-2H]- and (S)-[1-13C;2-2H]malonates.
    Biochemistry, 1992, Sep-22, Volume: 31, Issue:37

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Acyltransferases; Ligases; Malonates; Malonyl Coenzyme A; Mass Spectrometry; Multienzyme Complexes; Oxidoreductases; Penicillium; Stereoisomerism

1992
Purification and characterization of an unusually large fatty acid synthase from Mycobacterium tuberculosis var. bovis BCG.
    Archives of biochemistry and biophysics, 1992, Volume: 295, Issue:2

    Topics: Acetyl Coenzyme A; Amino Acids; Blotting, Western; Coenzyme A; Electrophoresis, Polyacrylamide Gel; Fatty Acid Synthases; Hydrogen-Ion Concentration; Malonyl Coenzyme A; Mycobacterium; Mycobacterium bovis; Substrate Specificity

1992
The origin of free brain malonate.
    Neurochemical research, 1991, Volume: 16, Issue:2

    Topics: Acetates; Acetic Acid; Acetyl Coenzyme A; Aging; Animals; Brain; Butyrates; Butyric Acid; Carbon Radioisotopes; Glutamates; Glutamic Acid; Kinetics; Malonates; Malonyl Coenzyme A; Rats

1991
Acetoacetyl-acyl carrier protein synthase. A target for the antibiotic thiolactomycin.
    The Journal of biological chemistry, 1989, May-05, Volume: 264, Issue:13

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Acetyl Coenzyme A; Acyl Carrier Protein; Acyltransferases; Drug Resistance, Microbial; Escherichia coli; Fatty Acids; Kinetics; Lactones; Malonyl Coenzyme A; Thiophenes

1989
Existence of acetyl-CoA-dependent chain elongation system in hepatic peroxisomes of rat: effects of clofibrate and di-(2-ethylhexyl)phthalate on the activity.
    Archives of biochemistry and biophysics, 1989, Volume: 274, Issue:1

    Topics: Acetyl Coenzyme A; Acyl-CoA Dehydrogenases; Animals; Cell Fractionation; Centrifugation, Density Gradient; Clofibrate; Diethylhexyl Phthalate; Fatty Acid Desaturases; Fatty Acids; Kinetics; Liver; Male; Malonyl Coenzyme A; Microbodies; Phthalic Acids; Rats; Rats, Inbred Strains; Reference Values

1989
Effects of dietary nutrients on substrate and effector levels of lipogenic enzymes, and lipogenesis from tritiated water in rat liver.
    Biochimica et biophysica acta, 1986, Sep-12, Volume: 878, Issue:2

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Animals; Cyclic AMP; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Fatty Acid Synthases; Fatty Acids; Glucagon; Glucosephosphate Dehydrogenase; Insulin; Liver; Male; Malonyl Coenzyme A; Rats; Rats, Inbred Strains; Tritium

1986
Direct assay for phosphotransacetylase and acetyl-coenzyme A carboxylase by high-performance liquid chromatography.
    Analytical biochemistry, 1986, Volume: 158, Issue:1

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Acetyltransferases; Animals; Chromatography, High Pressure Liquid; Ligases; Malonyl Coenzyme A; Phosphate Acetyltransferase

1986
[Formation of mevalonic acid, sterols and bile acids from [1-14C]acetyl-CoA and [2-14C]malonyl-CoA in the liver of rabbits with experimental hypercholesterolemia].
    Biokhimiia (Moscow, Russia), 1987, Volume: 52, Issue:2

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Animals; Bile Acids and Salts; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent; Hypercholesterolemia; Liver; Malonyl Coenzyme A; Mevalonic Acid; Rabbits; Sterols; Substrate Specificity

1987
Regulation of fatty acid synthesis and malonyl-CoA content in mouse brown adipose tissue in response to cold-exposure, starvation or re-feeding.
    The Biochemical journal, 1987, Apr-15, Volume: 243, Issue:2

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Acyl Coenzyme A; Adipose Tissue, Brown; Animals; Blood Glucose; Citrates; Cold Temperature; Fatty Acid Synthases; Fatty Acids; Female; Food; Malonyl Coenzyme A; Mice; Starvation

1987
Changes in the intracellular concentration of acetyl-CoA and malonyl-CoA in relation to the carbon and energy metabolism of Escherichia coli K12.
    Journal of general microbiology, 1988, Volume: 134, Issue:8

    Topics: Acetyl Coenzyme A; Carbon; Culture Media; Energy Metabolism; Escherichia coli; Glucose; Malonyl Coenzyme A

1988
In vitro stabilization of 6-methylsalicylic acid synthetase from Penicillium urticae.
    Canadian journal of microbiology, 1988, Volume: 34, Issue:1

    Topics: Acetyl Coenzyme A; Acyltransferases; Ascorbic Acid; Dithiothreitol; Drug Stability; Half-Life; Hydrogen-Ion Concentration; Kinetics; Ligases; Malonyl Coenzyme A; Multienzyme Complexes; NADP; Oxidoreductases; Patulin; Penicillium; Peptide Hydrolases; Phenylmethylsulfonyl Fluoride; Protein Conformation; Sulfhydryl Compounds

1988
Active site organization of bacterial type I fatty acid synthetase.
    Journal of biochemistry, 1987, Volume: 102, Issue:6

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Acetyl Coenzyme A; Binding Sites; Binding, Competitive; Brevibacterium; Chemical Phenomena; Chemistry; Dithionitrobenzoic Acid; Electrophoresis, Polyacrylamide Gel; Fatty Acid Synthases; Fluorometry; Iodoacetamide; Malonyl Coenzyme A; Palmitoyl Coenzyme A; Pancreatic Elastase; Peptide Fragments; Protein Binding; Transferases; Trypsin

1987
Consequences of reduced intracellular coenzyme A content in Escherichia coli.
    Journal of bacteriology, 1986, Volume: 166, Issue:3

    Topics: Acetyl Coenzyme A; Alanine; Citric Acid Cycle; Coenzyme A; Escherichia coli; Glutathione; Malonyl Coenzyme A; Mutation; Phospholipids

1986
Different sites of inhibition of carnitine palmitoyltransferase by malonyl-CoA, and by acetyl-CoA and CoA, in human skeletal muscle.
    The Biochemical journal, 1987, Jul-01, Volume: 245, Issue:1

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Acyltransferases; Binding Sites; Carnitine O-Palmitoyltransferase; Coenzyme A; Humans; In Vitro Techniques; Malonyl Coenzyme A; Muscles; Octoxynol; Polyethylene Glycols

1987
A biochemical basis for depressed ketogenesis in sepsis.
    The Journal of trauma, 1986, Volume: 26, Issue:5

    Topics: Acetyl Coenzyme A; Animals; Carnitine O-Acetyltransferase; Fatty Acids; Infections; Ketone Bodies; Liver; Male; Malonyl Coenzyme A; Oxidation-Reduction; Rats; Rats, Inbred Strains

1986
Thiol/disulfide redox equilibrium and kinetic behavior of chicken liver fatty acid synthase.
    The Journal of biological chemistry, 1986, Oct-05, Volume: 261, Issue:28

    Topics: Acetyl Coenzyme A; Animals; Chickens; Disulfides; Dithionitrobenzoic Acid; Electrophoresis, Polyacrylamide Gel; Fatty Acid Synthases; Glutathione; Glutathione Disulfide; Hydrogen-Ion Concentration; Kinetics; Liver; Malonyl Coenzyme A; Mathematics; Oxidation-Reduction; Sulfhydryl Compounds

1986
A novel procedure for the preparation and characterization of catalytically active fatty acid synthetase immobilized on sepharose beads.
    The Journal of biological chemistry, 1987, Feb-05, Volume: 262, Issue:4

    Topics: Acetyl Coenzyme A; Enzymes, Immobilized; Fatty Acid Synthases; Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Malonyl Coenzyme A; Methods; Sepharose

1987
Amino acid sequence around the active-site serine residue in the acyltransferase domain of goat mammary fatty acid synthetase.
    The Biochemical journal, 1985, Apr-01, Volume: 227, Issue:1

    Topics: Acetyl Coenzyme A; Acyltransferases; Amino Acid Sequence; Animals; Binding Sites; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Fatty Acid Synthases; Female; Goats; Malonyl Coenzyme A; Mammary Glands, Animal; Peptide Fragments; Serine

1985
Fatty acid biosynthesis in the peripheral nervous system of normal and Trembler mice.
    Biochimica et biophysica acta, 1986, Feb-28, Volume: 875, Issue:3

    Topics: Acetyl Coenzyme A; Animals; Chromatography, Gas; Chromatography, Thin Layer; Fatty Acid Synthases; Fatty Acids; Malonyl Coenzyme A; Mice; Mice, Neurologic Mutants; NADP; Nerve Tissue Proteins; Oxidation-Reduction; Peripheral Nerves; Subcellular Fractions

1986
Malonyl-CoA: acetyl-CoA cycling. A new micromethod for determination of acyl-CoAs with malonate decarboxylase.
    Biochimica et biophysica acta, 1985, Mar-27, Volume: 834, Issue:1

    Topics: Acetate Kinase; Acetyl Coenzyme A; Acyl Coenzyme A; Carboxy-Lyases; Hot Temperature; Hydrogen-Ion Concentration; Malonyl Coenzyme A; Microchemistry; Pseudomonas

1985
Distribution of reaction intermediates on chicken liver fatty acid synthase.
    Biochemistry, 1985, Apr-23, Volume: 24, Issue:9

    Topics: Acetyl Coenzyme A; Animals; Chickens; Chromatography, High Pressure Liquid; Fatty Acid Synthases; Liver; Malonyl Coenzyme A; Models, Chemical; NADP; Trypsin

1985
Evidence that the medium-chain acyltransferase of lactating-goat mammary-gland fatty acid synthetase is identical with the acetyl/malonyltransferase.
    The Biochemical journal, 1985, May-01, Volume: 227, Issue:3

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Acyltransferases; Amino Acid Sequence; Animals; Binding Sites; Fatty Acid Synthases; Female; Formates; Goats; Lactation; Malonyl Coenzyme A; Mammary Glands, Animal; Pregnancy

1985
Inhibition of lipid synthesis by beta beta'-tetramethyl-substituted, C14-C22, alpha, omega-dicarboxylic acids in cultured rat hepatocytes.
    The Journal of biological chemistry, 1985, Jul-15, Volume: 260, Issue:14

    Topics: Acetyl Coenzyme A; Animals; Biological Transport; Cells, Cultured; Cholesterol; Citrates; Citric Acid; Dicarboxylic Acids; Dose-Response Relationship, Drug; Glucose; Lipids; Liver; Malonyl Coenzyme A; Methylation; Mitochondria, Liver; Palmitic Acid; Palmitic Acids; Rats; Time Factors

1985
Mechanism of activation of bovine kidney pyruvate dehydrogenase a kinase by malonyl-CoA and enzyme-catalyzed decarboxylation of malonyl-CoA.
    European journal of biochemistry, 1985, Jul-01, Volume: 150, Issue:1

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Acylation; Animals; Catalysis; Cattle; Decarboxylation; Enzyme Activation; Formates; Ketoglutarate Dehydrogenase Complex; Kidney; Kinetics; Malonyl Coenzyme A; Protein Kinases; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvate Dehydrogenase Complex

1985
Assay of fatty acid synthetase by mass fragmentography using [13C]malonyl-CoA.
    Journal of biochemistry, 1985, Volume: 97, Issue:3

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Carbon Isotopes; Chemical Phenomena; Chemistry; Decarboxylation; Fatty Acid Synthases; Gas Chromatography-Mass Spectrometry; Guinea Pigs; Malonyl Coenzyme A; Rats; Substrate Specificity; Temperature

1985
Modification of mammalian fatty acid synthetase activity by NADP.
    FEBS letters, 1985, Sep-23, Volume: 189, Issue:2

    Topics: Acetyl Coenzyme A; Animals; Fatty Acid Synthases; Kinetics; Liver; Malonyl Coenzyme A; NADP; Rats

1985
Effects of DL-2-bromopalmitoyl-CoA and bromoacetyl-CoA in rat liver and heart mitochondria. Inhibition of carnitine palmitoyltransferase and displacement of [14C]malonyl-CoA from mitochondrial binding sites.
    The Biochemical journal, 1985, Aug-15, Volume: 230, Issue:1

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Acyltransferases; Animals; Binding Sites; Carnitine Acyltransferases; Carnitine O-Palmitoyltransferase; Coenzyme A; Kinetics; Malonyl Coenzyme A; Mitochondria; Mitochondria, Heart; Mitochondria, Liver; Palmitoyl Coenzyme A; Rats

1985
Stoichiometry of substrate binding to rat liver fatty acid synthetase.
    The Biochemical journal, 1985, Sep-01, Volume: 230, Issue:2

    Topics: Acetates; Acetic Acid; Acetyl Coenzyme A; Animals; Binding Sites; Cysteamine; Cysteine; Fatty Acid Synthases; Iodoacetamide; Liver; Malonates; Malonyl Coenzyme A; Pantetheine; Rats

1985
Aspects of lipid metabolism in the foetal, neonatal and adult monogastric mammal.
    Biochemical Society transactions, 1980, Volume: 8, Issue:3

    Topics: Acetate-CoA Ligase; Acetyl Coenzyme A; Acyl Coenzyme A; Adipose Tissue; Aging; Animals; Animals, Newborn; Fatty Acids; Female; Fetus; Lipid Metabolism; Liver; Malonyl Coenzyme A; Pregnancy; Species Specificity

1980
[Activities of 3-hydroxy-3-methylglutaryl-CoA reductase and acetyl-CoA carboxylase and rate of biosynthesis of mevalonic acid, squalene, sterols and fatty acids from [1-14C]acetyl-CoA and [2-14C]malonyl-CoA in rat liver: changes induced by daily rhythm].
    Biokhimiia (Moscow, Russia), 1981, Volume: 46, Issue:1

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Animals; Carbon Radioisotopes; Circadian Rhythm; Fatty Acids; Hydroxymethylglutaryl CoA Reductases; Kinetics; Ligases; Liver; Male; Malonyl Coenzyme A; Mevalonic Acid; Radioisotope Dilution Technique; Rats; Squalene; Sterols

1981
[Activities of 3-hydroxyl-3-methylglutaryl-CoA reductase and acetyl-CoA carboxylase and the rate of mevalonic acid, squalene, sterol and fatty acid biosynthesis from [1-14C]acetyl-CoA and [2-14C]malonyl-CoA in rat liver: effects of Triton WR 1339, starvat
    Biokhimiia (Moscow, Russia), 1981, Volume: 46, Issue:2

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Animals; Fatty Acids; Humans; Hydroxymethylglutaryl CoA Reductases; Kinetics; Ligases; Liver; Malonyl Coenzyme A; Mevalonic Acid; Polyethylene Glycols; Rats; Squalene; Starvation; Sterols

1981
Fatty acid synthesis in mitochondria of Euglena gracilis.
    European journal of biochemistry, 1984, Jul-02, Volume: 142, Issue:1

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Acyl-CoA Dehydrogenases; Adenosine Triphosphate; Chromatography, DEAE-Cellulose; Cytosol; Euglena gracilis; Fatty Acids; Kinetics; Malonyl Coenzyme A; Microsomes; Mitochondria; NAD; NADP; Substrate Specificity

1984
Rat hepatic microsomal acetoacetyl-CoA reductase. A beta-ketoacyl-CoA reductase distinct from the long chain beta-ketoacyl-CoA reductase component of the microsomal fatty acid chain elongation system.
    The Journal of biological chemistry, 1984, Jun-25, Volume: 259, Issue:12

    Topics: Acetoacetates; Acetyl Coenzyme A; Acyl Coenzyme A; Alcohol Oxidoreductases; Animals; Dietary Carbohydrates; Fatty Acid Synthases; Kinetics; Male; Malonyl Coenzyme A; Microsomes, Liver; NAD; Rats; Rats, Inbred Strains

1984
Metabolism of malonic semialdehyde in man.
    The Biochemical journal, 1983, Oct-15, Volume: 216, Issue:1

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Alanine; Carbon Dioxide; Carboxy-Lyases; Cell Line; Fibroblasts; Humans; Liver; Malonates; Malondialdehyde; Malonyl Coenzyme A; Mitochondria; Oxidation-Reduction

1983
Malonate, malonyl-coenzyme A, and acetyl-coenzyme A in developing rat brain.
    Journal of neurochemistry, 1984, Volume: 43, Issue:2

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Aging; Animals; Bacterial Proteins; Brain; Carboxy-Lyases; Coenzyme A Ligases; Female; Gestational Age; Malonates; Malonyl Coenzyme A; Pregnancy; Pseudomonas fluorescens; Rats; Rats, Inbred Strains

1984
Kinetic properties of fatty acid synthetase of Neurospora crassa.
    Microbios, 1980, Volume: 28, Issue:112

    Topics: Acetyl Coenzyme A; Citrates; Fatty Acid Synthases; Hydrogen-Ion Concentration; Kinetics; Malonyl Coenzyme A; Manganese; Neurospora; Neurospora crassa; Palmitoyl Coenzyme A

1980
The multifunctional polypeptide chains of rabbit-mammary fatty-acid synthase. Stoichiometry of active sites and active-site mapping using limited proteolysis.
    European journal of biochemistry, 1983, Jan-17, Volume: 130, Issue:1

    Topics: Acetyl Coenzyme A; Animals; Binding Sites; Electrophoresis, Polyacrylamide Gel; Fatty Acid Synthases; Female; Malonyl Coenzyme A; Mammary Glands, Animal; Pancreatic Elastase; Pantetheine; Peptide Fragments; Rabbits; Sulfhydryl Compounds

1983
Inhibition by acetyl-CoA of hepatic carnitine acyltransferase and fatty acid oxidation.
    The Biochemical journal, 1983, Nov-15, Volume: 216, Issue:2

    Topics: Acetyl Coenzyme A; Acyltransferases; Animals; Carnitine O-Palmitoyltransferase; Depression, Chemical; Fatty Acids; Female; In Vitro Techniques; Ketone Bodies; Liver; Male; Malonyl Coenzyme A; Mitochondria, Liver; Oxidation-Reduction; Pregnancy; Rats; Rats, Inbred Strains; Starvation

1983
[Biosynthesis of mevalonic acid, sterols and bile acids from acetyl-CoA and malonyl-CoA in the human liver].
    Biokhimiia (Moscow, Russia), 1983, Volume: 48, Issue:11

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Bile Acids and Salts; Carbon Radioisotopes; Humans; Kinetics; Liver; Malonyl Coenzyme A; Mevalonic Acid; Sterols

1983
Transient kinetic studies of fatty acid synthetase. A kinetic self-editing mechanism for the loading of acetyl and malonyl residues and the role of coenzyme A.
    The Journal of biological chemistry, 1984, Jan-10, Volume: 259, Issue:1

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Chickens; Fatty Acid Synthases; Kinetics; Male; Malonyl Coenzyme A; Mathematics; NADP; Oxidation-Reduction

1984
Determination of malonyl-coenzyme A in rat heart, kidney, and liver: a comparison between acetyl-coenzyme A and butyryl-coenzyme A as fatty acid synthase primers in the assay procedure.
    Analytical biochemistry, 1984, Volume: 138, Issue:1

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Fatty Acid Synthases; Kidney; Liver; Male; Malonyl Coenzyme A; Myocardium; Rats; Rats, Inbred Strains

1984
Kinetic studies of the fatty acid synthetase multienzyme complex from Euglena gracilis variety bacillaris.
    The Biochemical journal, 1981, Nov-01, Volume: 199, Issue:2

    Topics: Acetyl Coenzyme A; Euglena gracilis; Fatty Acid Synthases; Kinetics; Malonyl Coenzyme A; NAD; NADP; Substrate Specificity

1981
Inactivation of 3-oxoacyl synthetase activity of pigeon liver fatty acid synthetase by S-(4-bromo-2,3-dioxobutyl)-coenzyme A.
    European journal of biochemistry, 1983, Jan-17, Volume: 130, Issue:1

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Acetyl Coenzyme A; Acetyltransferases; Acyl-Carrier Protein S-Acetyltransferase; Acyltransferases; Amino Acids; Animals; Coenzyme A; Columbidae; Cysteine; Enzyme Activation; Fatty Acid Synthases; Iodoacetamide; Kinetics; Liver; Malonyl Coenzyme A; Pantetheine; Spectrophotometry

1983
Propionyl-Coa induced synthesis of even-chain-length fatty acids by fatty acid synthetase from Brevibacterium ammoniagenes.
    Journal of biochemistry, 1982, Volume: 91, Issue:1

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Brevibacterium; Chemical Phenomena; Chemistry; Deuterium; Fatty Acid Synthases; Fatty Acids; Malonyl Coenzyme A; Oleic Acids; Stearic Acids; Substrate Specificity

1982
Biosynthesis of platelet-activating factor (PAF)acether). III. Formation of PAF-acether from synthetic substrates by stimulated murine macrophages.
    Journal of immunology (Baltimore, Md. : 1950), 1982, Volume: 129, Issue:2

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Ascitic Fluid; Lysophosphatidylcholines; Macrophage Activation; Macrophages; Malonyl Coenzyme A; Mice; Palmitoyl Coenzyme A; Platelet Activating Factor; Rabbits; Rats; Rats, Inbred Strains; Zymosan

1982
[Biosynthesis of cholic and chenodeoxycholic acids from [1-14C]acetyl-CoA and [2-14C]malonyl-CoA in a reconstituted system from the rat liver].
    Biokhimiia (Moscow, Russia), 1981, Volume: 46, Issue:3

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Carbon Radioisotopes; Chenodeoxycholic Acid; Cholesterol, Dietary; Cholic Acids; Kinetics; Liver; Male; Malonyl Coenzyme A; Rats

1981
Irreversible inactivation of chicken liver fatty acid synthetase by its substrates acetyl and malonyl CoA. Effect of temperature and NADP n fatty acid and triacetic acid lactone synthesis.
    Biochemical and biophysical research communications, 1981, Apr-15, Volume: 99, Issue:3

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Chickens; Fatty Acid Synthases; Fatty Acids; Liver; Malonyl Coenzyme A; NADP; Pyrans; Pyrones; Temperature

1981
Inactivation of chicken liver fatty acid synthetase by malonyl coenzyme A. Effects of acetyl coenzyme A and nicotinamide adenine dinucleotide phosphate.
    Biochemistry, 1981, Jun-09, Volume: 20, Issue:12

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Chickens; Circular Dichroism; Dithiothreitol; Fatty Acid Synthases; Kinetics; Liver; Malonyl Coenzyme A; NAD; NADP; Oxidation-Reduction

1981
Coenzyme A is required for rat liver fatty acid synthetase activity.
    The Journal of biological chemistry, 1980, Feb-25, Volume: 255, Issue:4

    Topics: Acetyl Coenzyme A; Adenosine Diphosphate; Adenosine Triphosphate; Animals; ATP Citrate (pro-S)-Lyase; Citrates; Coenzyme A; Fatty Acid Synthases; Kinetics; Liver; Malonyl Coenzyme A; Rats

1980
Primer specificity of mammalian mammary gland fatty acid synthetases.
    Biochemical and biophysical research communications, 1980, Aug-29, Volume: 95, Issue:4

    Topics: Acetyl Coenzyme A; Animals; Cattle; Fatty Acid Synthases; Female; Goats; In Vitro Techniques; Malonyl Coenzyme A; Mammary Glands, Animal; Rabbits; Rats; Species Specificity; Substrate Specificity

1980
Substrate control of termination of fatty acid biosynthesis by fatty acid synthetase from Brevibacterium ammoniagenes.
    Journal of biochemistry, 1980, Volume: 88, Issue:2

    Topics: Acetyl Coenzyme A; Brevibacterium; Fatty Acid Synthases; Fatty Acids; Kinetics; Malonyl Coenzyme A; Oleic Acids

1980
Biochemical properties of cytochrome b5-dependent microsomal fatty acid elongation and identification of products.
    The Journal of biological chemistry, 1980, Dec-10, Volume: 255, Issue:23

    Topics: Acetyl Coenzyme A; Animals; Cytochromes; Cytochromes b5; Fatty Acids; Hydrogen-Ion Concentration; Kinetics; Male; Malonyl Coenzyme A; Microsomes, Liver; NAD; NADP; Oxidation-Reduction; Rats

1980
Dissociation of dimeric 6-hydroxymellein synthase, a polyketide biosynthetic enzyme in carrot cell extracts, with loss of keto-reducing activity.
    Archives of biochemistry and biophysics, 1995, Aug-01, Volume: 321, Issue:1

    Topics: Acetyl Coenzyme A; Acyltransferases; Binding Sites; Chromatography, High Pressure Liquid; Daucus carota; Kinetics; Ligases; Macromolecular Substances; Malonyl Coenzyme A; Models, Structural; Multienzyme Complexes; Oxidation-Reduction; Oxidoreductases; Substrate Specificity

1995
Cytokines inhibit fatty acid oxidation in isolated rat hepatocytes: synergy among TNF, IL-6, and IL-1.
    Shock (Augusta, Ga.), 1994, Volume: 1, Issue:2

    Topics: Acetyl Coenzyme A; Alanine; Animals; Cells, Cultured; Citric Acid Cycle; Depression, Chemical; Drug Synergism; Energy Metabolism; Fatty Acids; Interleukin-1; Interleukin-6; Ketone Bodies; Liver; Malonyl Coenzyme A; Models, Biological; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha

1994
Regulation of malonyl-CoA metabolism by acyl-acyl carrier protein and beta-ketoacyl-acyl carrier protein synthases in Escherichia coli.
    The Journal of biological chemistry, 1995, Jun-30, Volume: 270, Issue:26

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Acetyl Coenzyme A; Acyl Carrier Protein; Escherichia coli; Fatty Acids; Malonyl Coenzyme A; Phospholipids

1995
Acetyl-CoA carboxylase involvement in the rapid maturation of fatty acid oxidation in the newborn rabbit heart.
    The Journal of biological chemistry, 1994, Oct-14, Volume: 269, Issue:41

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Age Factors; Animals; Animals, Newborn; Carnitine O-Palmitoyltransferase; Citrates; Dose-Response Relationship, Drug; Fatty Acids; Glucagon; Heart; Insulin; Malonyl Coenzyme A; Mitochondria, Heart; Myocardium; Oxidation-Reduction; Palmitates; Perfusion; Rabbits

1994
Acetoacyl-acyl carrier protein synthase from avocado: its purification, characterisation and clear resolution from acetyl CoA:ACP transacylase.
    Plant molecular biology, 1994, Volume: 25, Issue:2

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Acetyl Coenzyme A; Acetyltransferases; Acyl-Carrier Protein S-Acetyltransferase; Buffers; Cerulenin; Fruit; Hydrogen-Ion Concentration; Kinetics; Malonyl Coenzyme A; Molecular Weight; Thiophenes

1994
Enzymatic synthesis of a bacterial polyketide from acetyl and malonyl coenzyme A.
    Science (New York, N.Y.), 1993, Dec-03, Volume: 262, Issue:5139

    Topics: Acetyl Coenzyme A; Amino Acid Sequence; Anthracenes; Antibody Specificity; Fatty Acid Synthases; Malonyl Coenzyme A; Molecular Sequence Data; Multienzyme Complexes; Streptomyces; Substrate Specificity

1993
Polyketide biosynthesis: molecular recognition or genetic programming?
    Science (New York, N.Y.), 1994, Jan-21, Volume: 263, Issue:5145

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Anthraquinones; Anti-Bacterial Agents; Cell-Free System; Erythromycin; Malonyl Coenzyme A; Multienzyme Complexes; Naphthacenes; Streptomyces

1994
Stereospecific acyl transfers on the erythromycin-producing polyketide synthase.
    Science (New York, N.Y.), 1994, Jan-21, Volume: 263, Issue:5145

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Erythromycin; Malonyl Coenzyme A; Molecular Conformation; Multienzyme Complexes; Racemases and Epimerases; Saccharopolyspora; Stereoisomerism; Substrate Specificity

1994
Coenzyme A biosynthesis in plants: partial purification and characterization of pantothenate kinase from spinach.
    Archives of biochemistry and biophysics, 1993, Volume: 301, Issue:2

    Topics: Acetyl Coenzyme A; Acyl Carrier Protein; Adenosine Diphosphate; Amino Acids; Brassica; Cell Compartmentation; Chloroplasts; Coenzyme A; Dose-Response Relationship, Drug; Isoenzymes; Malonyl Coenzyme A; Phosphoric Monoester Hydrolases; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Plants, Edible; Seeds; Subcellular Fractions

1993
Transacylase-like structure and its role in substrate channeling of 6-hydroxymellein synthase, a multifunctional polyketide biosynthetic enzyme in carrot cell extracts.
    FEBS letters, 1996, Jan-22, Volume: 379, Issue:1

    Topics: Acetyl Coenzyme A; Acyl Carrier Protein; Acyltransferases; Binding Sites; Cysteine; Daucus carota; Ligases; Malonyl Coenzyme A; Molecular Structure; Multienzyme Complexes; Oxidoreductases; Substrate Specificity; Sulfhydryl Compounds; Sulfhydryl Reagents; Sulfones

1996
Propionyl L-carnitine improvement of hypertrophied rat heart function is associated with an increase in cardiac efficiency.
    European journal of pharmacology, 1995, Nov-14, Volume: 286, Issue:2

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Adenosine Triphosphate; Animals; Cardiomegaly; Cardiotonic Agents; Carnitine; Heart; In Vitro Techniques; Male; Malonyl Coenzyme A; Myocardium; Rats; Rats, Inbred WKY

1995
Effect of NADPH-associated keto-reducing domain on substrate entry into 6-hydroxymellein synthase, a multifunctional polyketide synthetic enzyme involved in phytoalexin biosynthesis in carrot.
    Archives of biochemistry and biophysics, 1996, Apr-01, Volume: 328, Issue:1

    Topics: Acetyl Coenzyme A; Acyltransferases; Daucus carota; Kinetics; Ligases; Malonyl Coenzyme A; Models, Chemical; Multienzyme Complexes; NADP; Oxidoreductases; Phytoalexins; Plant Extracts; Pyrones; Sesquiterpenes; Terpenes

1996
Structural similarities between 6-methylsalicylic acid synthase from Penicillium patulum and vertebrate type I fatty acid synthase: evidence from thiol modification studies.
    Biochemistry, 1996, Sep-24, Volume: 35, Issue:38

    Topics: Acetone; Acetyl Coenzyme A; Acyltransferases; Amino Acid Sequence; Animals; Antifungal Agents; Binding Sites; Centrifugation, Density Gradient; Cerulenin; Cross-Linking Reagents; Dithionitrobenzoic Acid; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Fatty Acid Synthases; Iodoacetamide; Ligases; Malonyl Coenzyme A; Molecular Sequence Data; Molecular Weight; Multienzyme Complexes; Oxidoreductases; Penicillium; Protein Conformation; Serine Endopeptidases; Sulfhydryl Reagents

1996
Expression in Escherichia coli and refolding of the malonyl-/acetyltransferase domain of the multifunctional animal fatty acid synthase.
    The Journal of biological chemistry, 1996, Dec-06, Volume: 271, Issue:49

    Topics: Acetyl Coenzyme A; Acetyl-CoA C-Acetyltransferase; Acyl-Carrier Protein S-Malonyltransferase; Acyltransferases; Amino Acid Sequence; Animals; Base Sequence; Chickens; Diethyl Pyrocarbonate; Escherichia coli; Escherichia coli Proteins; Fatty Acid Synthase, Type II; Fatty Acid Synthases; Humans; Kinetics; Malonyl Coenzyme A; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Rats; Sequence Alignment; Structure-Activity Relationship

1996
Changes in the size and composition of intracellular pools of nonesterified coenzyme A and coenzyme A thioesters in aerobic and facultatively anaerobic bacteria.
    Applied and environmental microbiology, 1997, Volume: 63, Issue:2

    Topics: Acetyl Coenzyme A; Anaerobiosis; Bacteria, Aerobic; Cerulenin; Coenzyme A; Energy Metabolism; Enzyme Inhibitors; Esters; Fatty Acid Synthases; Fatty Acids; Feedback; Gene Expression Regulation, Enzymologic; Glucose; Gram-Negative Facultatively Anaerobic Rods; Malonyl Coenzyme A; Potassium Cyanide; Species Specificity; Sulfhydryl Compounds

1997
Alteration of the substrate specificity of the malonyl-CoA/acetyl-CoA:acyl carrier protein S-acyltransferase domain of the multifunctional fatty acid synthase by mutation of a single arginine residue.
    The Journal of biological chemistry, 1997, May-02, Volume: 272, Issue:18

    Topics: Acetyl Coenzyme A; Amino Acid Sequence; Animals; Arginine; Cloning, Molecular; Coenzyme A-Transferases; Conserved Sequence; Escherichia coli; Fatty Acid Synthases; Kinetics; Malonyl Coenzyme A; Mutagenesis, Site-Directed; Point Mutation; Rats; Recombinant Proteins; Substrate Specificity

1997
[Rapid induction of hepatic acetyl-CoA carboxylase activity after estradiol benzoate injection in the quail].
    FEBS letters, 1981, Nov-02, Volume: 134, Issue:1

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Animals; Coturnix; Enzyme Induction; Estradiol; Fatty Acids; Kinetics; Liver; Malonyl Coenzyme A

1981
Stromal concentrations of coenzyme A and its esters are insufficient to account for rates of chloroplast fatty acid synthesis: evidence for substrate channelling within the chloroplast fatty acid synthase.
    The Biochemical journal, 1997, Oct-01, Volume: 327 ( Pt 1)

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Cell Extracts; Cell Membrane Permeability; Chloroplasts; Chromatography, High Pressure Liquid; Coenzyme A; Detergents; Fatty Acid Synthases; Fatty Acids; Glutathione; Malonyl Coenzyme A; Octoxynol; Pisum sativum; Spinacia oleracea

1997
Fatty acid synthesis of an eicosapentaenoic acid-producing bacterium: de novo synthesis, chain elongation, and desaturation systems.
    Journal of biochemistry, 1997, Volume: 122, Issue:2

    Topics: Acetyl Coenzyme A; Acyl Carrier Protein; Cerulenin; Eicosapentaenoic Acid; Enzyme Inhibitors; Fatty Acid Desaturases; Fatty Acids; Gram-Negative Facultatively Anaerobic Rods; Malonyl Coenzyme A; Models, Chemical; NAD; NADP

1997
Inactivation of the polyketide synthase, 6-methylsalicylic acid synthase, by the specific modification of Cys-204 of the beta-ketoacyl synthase by the fungal mycotoxin cerulenin.
    The Biochemical journal, 1998, Mar-01, Volume: 330 ( Pt 2)

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Acetyl Coenzyme A; Acyltransferases; Alkylation; Antifungal Agents; Binding, Competitive; Cerulenin; Cyanogen Bromide; Cysteine; Iodoacetamide; Kinetics; Ligases; Malonyl Coenzyme A; Models, Chemical; Multienzyme Complexes; Oxidoreductases; Penicillium; Peptide Mapping; Serine Endopeptidases; Staphylococcus aureus

1998
Inactivation of enoyl-CoA reductase in pigeon liver fatty acid synthetase by pyridoxal 5'-phosphate: evidence for the presence of one lysine residue at the active site.
    Journal of enzyme inhibition, 1998, Volume: 13, Issue:3

    Topics: Acetyl Coenzyme A; Animals; Binding Sites; Columbidae; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Enzyme Inhibitors; Fatty Acid Synthases; Kinetics; Liver; Lysine; Malonyl Coenzyme A; Oxidoreductases; Pyridoxal Phosphate; Spectrometry, Fluorescence

1998
Changes in size of intracellular pools of coenzyme A and its thioesters in Escherichia coli K-12 cells to various carbon sources and stresses.
    Bioscience, biotechnology, and biochemistry, 1998, Volume: 62, Issue:6

    Topics: Acetyl Coenzyme A; Carbon; Coenzyme A; Culture Media; Escherichia coli; Glucose; Hydrogen-Ion Concentration; Malonyl Coenzyme A; Osmotic Pressure; Temperature

1998
Regulation of spinach chloroplast acetyl-CoA carboxylase.
    Archives of biochemistry and biophysics, 1998, Nov-15, Volume: 359, Issue:2

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Acyl Coenzyme A; Chloroplasts; Coenzyme A; Darkness; Dithiothreitol; Enzyme Activation; Hydrogen-Ion Concentration; Light; Malonyl Coenzyme A; Spinacia oleracea; Subcellular Fractions; Thioredoxins

1998
A gene cluster encoding malonyl-CoA decarboxylase (MatA), malonyl-CoA synthetase (MatB) and a putative dicarboxylate carrier protein (MatC) in Rhizobium trifolii--cloning, sequencing, and expression of the enzymes in Escherichia coli.
    European journal of biochemistry, 1998, Oct-15, Volume: 257, Issue:2

    Topics: Acetyl Coenzyme A; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Carboxy-Lyases; Carrier Proteins; Cloning, Molecular; Coenzyme A Ligases; Dicarboxylic Acid Transporters; DNA Primers; Escherichia coli; Malonates; Malonyl Coenzyme A; Molecular Sequence Data; Multigene Family; Rhizobium; Sequence Deletion

1998
Fatty acid synthase dimers containing catalytically active beta-ketoacyl synthase or malonyl/acetyltransferase domains in only one subunit can support fatty acid synthesis at the acyl carrier protein domains of both subunits.
    The Journal of biological chemistry, 1998, Dec-25, Volume: 273, Issue:52

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Acetyl Coenzyme A; Acyl Carrier Protein; Acyltransferases; Catalytic Domain; Dimerization; Fatty Acid Synthases; Fatty Acids; Malonyl Coenzyme A; Mutation

1998
Presence of acetyl coenzyme A (CoA) carboxylase and propionyl-CoA carboxylase in autotrophic Crenarchaeota and indication for operation of a 3-hydroxypropionate cycle in autotrophic carbon fixation.
    Journal of bacteriology, 1999, Volume: 181, Issue:4

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Acyl Coenzyme A; Aerobiosis; Biotin; Carbon Dioxide; Carboxy-Lyases; Chlorobi; Crenarchaeota; Genes, Archaeal; Lactic Acid; Malonyl Coenzyme A; Methylmalonyl-CoA Decarboxylase; Peptides; Sequence Homology; Succinic Acid; Sulfolobaceae

1999
Dissection of malonyl-coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase.
    Biochemistry, 2000, Feb-08, Volume: 39, Issue:5

    Topics: Acetyl Coenzyme A; Acyltransferases; Amino Acid Sequence; Amino Acid Substitution; Base Sequence; Coenzyme A; Crystallography, X-Ray; Decarboxylation; Enzyme Activation; Flavanones; Flavonoids; Malonyl Coenzyme A; Medicago sativa; Molecular Sequence Data; Multienzyme Complexes; Mutagenesis, Site-Directed; Plant Proteins; Recombinant Proteins; Spectrometry, Fluorescence; Structure-Activity Relationship; Titrimetry

2000
Sensitivity of CPT I to malonyl-CoA in trained and untrained human skeletal muscle.
    American journal of physiology. Endocrinology and metabolism, 2000, Volume: 278, Issue:3

    Topics: Acetyl Coenzyme A; Acetylcarnitine; Adult; Carnitine O-Palmitoyltransferase; Coenzyme A; Female; Humans; Hydrogen-Ion Concentration; Male; Malonyl Coenzyme A; Mitochondria, Muscle; Muscle, Skeletal; Physical Education and Training; Reference Values

2000
Tolerance and specificity of recombinant 6-methylsalicyclic acid synthase.
    Metabolic engineering, 1999, Volume: 1, Issue:2

    Topics: Acetyl Coenzyme A; Acyltransferases; Amino Acid Sequence; Base Sequence; Cloning, Molecular; Escherichia coli; Kinetics; Ligases; Malonyl Coenzyme A; Multienzyme Complexes; Mutagenesis, Site-Directed; Oxidoreductases; Penicillium; Recombinant Proteins; Saccharomyces cerevisiae; Substrate Specificity

1999
Purification and characterization of the fatty acid synthase from Bugula neritina.
    Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 2001, Volume: 128, Issue:3

    Topics: Acetyl Coenzyme A; Animals; Bryozoa; Chromatography, Gel; Chromatography, Ion Exchange; Cytosol; Fatty Acid Synthases; Hydrogen-Ion Concentration; Kinetics; Malonyl Coenzyme A; Molecular Weight; NAD; NADP; Substrate Specificity

2001
Regulation of myocardial fatty acid oxidation by substrate supply.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 281, Issue:4

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Adenylate Kinase; Aminoimidazole Carboxamide; Animals; Fatty Acids; Glycolysis; In Vitro Techniques; Male; Malonyl Coenzyme A; Myocardium; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Ribonucleotides; Substrate Specificity

2001
Enzymes involved in fatty acid and polyketide biosynthesis in Streptomyces glaucescens: role of FabH and FabD and their acyl carrier protein specificity.
    Biochemistry, 2002, Aug-20, Volume: 41, Issue:33

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Acetic Acid; Acetyl Coenzyme A; Acetyl-CoA C-Acetyltransferase; Acyl Carrier Protein; Amino Acid Sequence; Animals; Carbon Isotopes; Deuterium; Enzyme Activation; Fatty Acids; Malonyl Coenzyme A; Molecular Sequence Data; Multienzyme Complexes; Naphthacenes; Recombinant Proteins; Spodoptera; Streptomyces; Substrate Specificity; Transferases (Other Substituted Phosphate Groups)

2002
Probing the link between citrate and malonyl-CoA in perfused rat hearts.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:4

    Topics: Acetyl Coenzyme A; Animals; ATP Citrate (pro-S)-Lyase; Carbon Isotopes; Citrates; Citric Acid; Citric Acid Cycle; Gas Chromatography-Mass Spectrometry; In Vitro Techniques; Male; Malonyl Coenzyme A; Myocardial Contraction; Myocardium; Perfusion; Pyruvic Acid; Rats; Rats, Sprague-Dawley

2002
Quantitative analysis of loading and extender acyltransferases of modular polyketide synthases.
    Biochemistry, 2003, Jan-14, Volume: 42, Issue:1

    Topics: Acetyl Coenzyme A; Acyl Carrier Protein; Acyl Coenzyme A; Acyltransferases; Cysteamine; Genetic Vectors; Histidine; Kinetics; Malonyl Coenzyme A; Multienzyme Complexes; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Protein Subunits; Quantitative Structure-Activity Relationship; Sirolimus; Substrate Specificity

2003
Characterization of acetyl-CoA/propionyl-CoA carboxylase in Metallosphaera sedula. Carboxylating enzyme in the 3-hydroxypropionate cycle for autotrophic carbon fixation.
    European journal of biochemistry, 2003, Volume: 270, Issue:4

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Acyl Coenzyme A; Biotin; Blotting, Southern; Carbon Dioxide; Carbon-Nitrogen Ligases; Carboxy-Lyases; Catalysis; Cloning, Molecular; Escherichia coli; Fatty Acid Desaturases; Hot Temperature; Malonyl Coenzyme A; Methylmalonyl-CoA Decarboxylase; Oxidoreductases; Plasmids; Protein Subunits; Sulfolobaceae

2003
Functional analysis of a beta-ketoacyl-CoA synthase gene, MpFAE2, by gene silencing in the liverwort Marchantia polymorpha L.
    Bioscience, biotechnology, and biochemistry, 2003, Volume: 67, Issue:3

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Acetyl Coenzyme A; Amino Acid Sequence; Blotting, Northern; Blotting, Southern; Fatty Acids; Gene Silencing; Hepatophyta; Malonyl Coenzyme A; Molecular Sequence Data; Nucleic Acid Conformation; Plants, Genetically Modified; RNA Interference; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity

2003
The stable isotope-based dynamic metabolic profile of butyrate-induced HT29 cell differentiation.
    The Journal of biological chemistry, 2003, Aug-01, Volume: 278, Issue:31

    Topics: Acetyl Coenzyme A; Adenocarcinoma; Butyrates; Carbon Isotopes; Cell Differentiation; Cell Division; Colonic Neoplasms; Glucose; Glycolysis; HT29 Cells; Humans; Malonyl Coenzyme A; Oxidation-Reduction; Pancreatic Neoplasms; Pentose Phosphate Pathway

2003
THE FORMATION OF ACETOACETATE FROM ACETYL COENZYME A, MALONYL COENZYME A,AND PYRUVATE BY WASHED MITOCHONDRIA ISOLATED FROM GUINEA PIG LIVER.
    Canadian journal of biochemistry and physiology, 1963, Volume: 41

    Topics: Acetates; Acetoacetates; Acetyl Coenzyme A; Adenosine Triphosphate; Antimetabolites; Bicarbonates; Biotin; Carbon Isotopes; Chromatography; Coenzyme A; Egg White; Guinea Pigs; Lipid Metabolism; Liver; Malonates; Malonyl Coenzyme A; Mitochondria; Pharmacology; Pyruvates; Pyruvic Acid; Research

1963
SYNTHESIS OF MALONYL-COENZYME A FROM ACETYL-COENZYME A AND OXALOSUCCINATE IN MITOCHONDRIA.
    Biochimica et biophysica acta, 1963, Nov-08, Volume: 77

    Topics: Acetates; Acetyl Coenzyme A; Biotin; Carbon Isotopes; Chromatography; Citric Acid Cycle; Coenzyme A; Keto Acids; Malonates; Malonyl Coenzyme A; Manometry; Mitochondria; Myocardium; Rats; Research; Succinates

1963
Carboxymethylproline synthase (CarB), an unusual carbon-carbon bond-forming enzyme of the crotonase superfamily involved in carbapenem biosynthesis.
    The Journal of biological chemistry, 2004, Feb-20, Volume: 279, Issue:8

    Topics: Acetyl Coenzyme A; Amino Acid Sequence; Carbapenems; Carbon; Carbon-Carbon Lyases; Chromatography, Gel; Circular Dichroism; Cloning, Molecular; Dithionitrobenzoic Acid; Electrophoresis, Polyacrylamide Gel; Enoyl-CoA Hydratase; Glutamates; Glutamic Acid; Kinetics; Lactams; Magnetic Resonance Spectroscopy; Malonyl Coenzyme A; Mass Spectrometry; Models, Chemical; Molecular Sequence Data; Pectobacterium; Protein Binding; Recombinant Proteins; Sequence Homology, Amino Acid; Stereoisomerism; Thienamycins

2004
Role of the active site cysteine of DpgA, a bacterial type III polyketide synthase.
    Biochemistry, 2004, Feb-03, Volume: 43, Issue:4

    Topics: Acetyl Coenzyme A; Alanine; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Carbon Radioisotopes; Catalysis; Coenzyme A Ligases; Cysteine; Decarboxylation; Kinetics; Malonyl Coenzyme A; Molecular Sequence Data; Mutagenesis, Site-Directed; Substrate Specificity

2004
The first plant type III polyketide synthase that catalyzes formation of aromatic heptaketide.
    FEBS letters, 2004, Mar-26, Volume: 562, Issue:1-3

    Topics: Acetyl Coenzyme A; Amino Acid Sequence; Catalysis; Escherichia coli; Malonyl Coenzyme A; Molecular Sequence Data; Molecular Structure; Multienzyme Complexes; Mutagenesis, Site-Directed; Phylogeny; Plant Proteins; Rheum; Sequence Alignment

2004
Characterization of fatty acid synthase activity using scintillation proximity.
    Assay and drug development technologies, 2003, Volume: 1, Issue:1 Pt 2

    Topics: Acetyl Coenzyme A; Animals; Fatty Acid Synthases; In Vitro Techniques; Liver; Male; Malonyl Coenzyme A; Palmitic Acid; Rats; Reproducibility of Results; Scintillation Counting; Tritium

2003
Malonyl coenzyme a decarboxylase inhibition protects the ischemic heart by inhibiting fatty acid oxidation and stimulating glucose oxidation.
    Circulation research, 2004, May-14, Volume: 94, Issue:9

    Topics: Acetyl Coenzyme A; Animals; Carboxy-Lyases; Cardiotonic Agents; Energy Metabolism; Enzyme Inhibitors; Esters; Fatty Acids; Glucose; Glycolysis; Malonyl Coenzyme A; Mitochondria, Heart; Models, Animal; Myocardial Ischemia; Myocardium; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Swine

2004
Glucosinolate biosynthesis: demonstration and characterization of the condensing enzyme of the chain elongation cycle in Eruca sativa.
    Phytochemistry, 2004, Volume: 65, Issue:8

    Topics: 2-Isopropylmalate Synthase; Acetyl Coenzyme A; Brassicaceae; Cations, Divalent; Chloroplasts; Glucosinolates; Hydrolysis; Malate Synthase; Malonyl Coenzyme A; Mass Spectrometry; Methionine; Species Specificity; Substrate Specificity; Tritium

2004
Regulation of malonyl-CoA concentration and turnover in the normal heart.
    The Journal of biological chemistry, 2004, Aug-13, Volume: 279, Issue:33

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Animals; Biochemical Phenomena; Biochemistry; Carboxy-Lyases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart; Kinetics; Malonyl Coenzyme A; Myocardium; Perfusion; Rats; Rats, Sprague-Dawley; Swine; Time Factors

2004
In vitro modeling of fatty acid synthesis under conditions simulating the zonation of lipogenic [13C]acetyl-CoA enrichment in the liver.
    The Journal of biological chemistry, 2004, Oct-08, Volume: 279, Issue:41

    Topics: Acetyl Coenzyme A; Animals; Fatty Acids; Glucose; Lipid Metabolism; Liver; Liver Extracts; Malonyl Coenzyme A; Models, Theoretical; Rats; Subcellular Fractions; Time Factors

2004
Malonyl-CoA and carnitine in regulation of fat oxidation in human skeletal muscle during exercise.
    American journal of physiology. Endocrinology and metabolism, 2005, Volume: 288, Issue:1

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Acetylcarnitine; Adenylate Kinase; Adult; Carnitine; Dietary Carbohydrates; Exercise; Fatty Acids; Glucose; Glycogen; Heart Rate; Humans; Insulin; Male; Malonyl Coenzyme A; Muscle, Skeletal; Oxidation-Reduction; Pyruvate Dehydrogenase Complex

2005
[Lipogenesis: does it have a relevance in the obesity research?].
    Ugeskrift for laeger, 2004, May-31, Volume: 166, Issue:23

    Topics: Acetyl Coenzyme A; Dietary Carbohydrates; Humans; Hyperinsulinism; Lipid Metabolism; Lipids; Malonyl Coenzyme A; Obesity; Research

2004
Connection of propionyl-CoA metabolism to polyketide biosynthesis in Aspergillus nidulans.
    Genetics, 2004, Volume: 168, Issue:2

    Topics: Acetate-CoA Ligase; Acetyl Coenzyme A; Acyl Coenzyme A; Amino Acid Sequence; Aspergillus nidulans; Citrate (si)-Synthase; Gene Expression Regulation, Fungal; Malonates; Malonyl Coenzyme A; Methylmalonyl-CoA Decarboxylase; Molecular Sequence Data; Propionates; Sequence Homology, Amino Acid; Sterigmatocystin

2004
Peroxisomal and mitochondrial oxidation of fatty acids in the heart, assessed from the 13C labeling of malonyl-CoA and the acetyl moiety of citrate.
    The Journal of biological chemistry, 2005, Mar-11, Volume: 280, Issue:10

    Topics: Acetyl Coenzyme A; Acetylation; Acetylcarnitine; Animals; Carbon Isotopes; Citrates; Fatty Acids, Nonesterified; Kinetics; Male; Malonyl Coenzyme A; Mitochondria, Heart; Myocardium; Oxidation-Reduction; Peroxisomes; Rats; Rats, Sprague-Dawley

2005
Characterization of the inactivation of rat fatty acid synthase by C75: inhibition of partial reactions and protection by substrates.
    The Biochemical journal, 2005, Jun-15, Volume: 388, Issue:Pt 3

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase; 4-Butyrolactone; Acetyl Coenzyme A; Alcohol Oxidoreductases; Animals; Binding, Competitive; Dithiothreitol; Enzyme Activation; Fatty Acid Synthases; Kinetics; Liver; Malonyl Coenzyme A; NADP; Rats; Substrate Specificity; Temperature

2005
Probing peroxisomal beta-oxidation and the labelling of acetyl-CoA proxies with [1-(13C)]octanoate and [3-(13C)]octanoate in the perfused rat liver.
    The Biochemical journal, 2005, Jul-15, Volume: 389, Issue:Pt 2

    Topics: Acetates; Acetyl Coenzyme A; Acetylcarnitine; Animals; Caprylates; Carbon Isotopes; Citric Acid; Isotope Labeling; Ketone Bodies; Liver; Male; Malonyl Coenzyme A; Mitochondria, Liver; Oxidation-Reduction; Perfusion; Peroxisomes; Rats; Rats, Sprague-Dawley

2005
Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice.
    Cell metabolism, 2005, Volume: 2, Issue:1

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Dietary Fats; Diglycerides; Fasting; Fatty Liver; Glucose Tolerance Test; Glycerol-3-Phosphate O-Acyltransferase; Insulin Resistance; Liver; Lysophospholipids; Male; Malonyl Coenzyme A; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Multienzyme Complexes; Phenotype; Protein Serine-Threonine Kinases; Triglycerides

2005
Competition between acetate and oleate for the formation of malonyl-CoA and mitochondrial acetyl-CoA in the perfused rat heart.
    Journal of molecular and cellular cardiology, 2006, Volume: 41, Issue:5

    Topics: Acetates; Acetyl Coenzyme A; Animals; Fatty Acids; In Vitro Techniques; Male; Malonyl Coenzyme A; Mitochondria, Heart; Models, Cardiovascular; Myocardium; Oleic Acid; Oxidation-Reduction; Perfusion; Propionates; Rats; Rats, Sprague-Dawley

2006
Determination of acetyl-CoA and malonyl-CoA in germinating rice seeds using the LC-MS/MS technique.
    Bioscience, biotechnology, and biochemistry, 2006, Volume: 70, Issue:11

    Topics: Acetyl Coenzyme A; Chromatography, Liquid; Malonyl Coenzyme A; Mass Spectrometry; Oryza; Seedlings; Seeds; Time Factors

2006
Malonyl CoA control of fatty acid oxidation in the newborn heart in response to increased fatty acid supply.
    Canadian journal of physiology and pharmacology, 2006, Volume: 84, Issue:11

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Animals, Newborn; Carboxy-Lyases; Carnitine O-Palmitoyltransferase; Citric Acid Cycle; Dose-Response Relationship, Drug; Glucose; In Vitro Techniques; Malonyl Coenzyme A; Multienzyme Complexes; Myocardium; Oxidation-Reduction; Palmitic Acid; Protein Serine-Threonine Kinases; Rabbits

2006
Goat acetyl-coenzyme A carboxylase alpha: molecular characterization, polymorphism, and association with milk traits.
    Journal of dairy science, 2007, Volume: 90, Issue:2

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Animals; Cattle; Cell Count; DNA, Complementary; Fats; Gene Frequency; Genotype; Goats; Malonyl Coenzyme A; Milk; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Sequence Analysis, DNA; Sequence Homology; Sheep; Species Specificity

2007
Simultaneous quantification of malonyl-CoA and several other short-chain acyl-CoAs in animal tissues by ion-pairing reversed-phase HPLC/MS.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, Jun-15, Volume: 853, Issue:1-2

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Chromatography, High Pressure Liquid; Liver; Malonyl Coenzyme A; Mice; Molecular Structure; Muscle, Skeletal; Myocardium; Rats; Rats, Sprague-Dawley; Reproducibility of Results

2007
GNAT-like strategy for polyketide chain initiation.
    Science (New York, N.Y.), 2007, Nov-09, Volume: 318, Issue:5852

    Topics: Acetyl Coenzyme A; Acetyltransferases; Acyl Carrier Protein; Amino Acid Sequence; Carboxy-Lyases; Crystallography, X-Ray; Cyanobacteria; Cyclopropanes; Decarboxylation; Malonyl Coenzyme A; Models, Molecular; Molecular Sequence Data; Polyketide Synthases; Protein Conformation; Protein Structure, Tertiary; Thiazoles

2007
Differences in concentrations of acetyl-CoA and malonyl-CoA in shoots and roots of Zea mays.
    Bioscience, biotechnology, and biochemistry, 2008, Volume: 72, Issue:3

    Topics: Acetyl Coenzyme A; Darkness; Light; Malonyl Coenzyme A; Plant Roots; Plant Shoots; Zea mays

2008
Production of the polyketide 6-MSA in yeast engineered for increased malonyl-CoA supply.
    Metabolic engineering, 2008, Volume: 10, Issue:5

    Topics: Acetyl Coenzyme A; Acetyltransferases; Acyltransferases; Aspergillus nidulans; Ligases; Macrolides; Malonyl Coenzyme A; Multienzyme Complexes; Oxidoreductases; Penicillium; Peptide Elongation Factor 1; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salicylates

2008
Abrogation of hepatic ATP-citrate lyase protects against fatty liver and ameliorates hyperglycemia in leptin receptor-deficient mice.
    Hepatology (Baltimore, Md.), 2009, Volume: 49, Issue:4

    Topics: Acetyl Coenzyme A; Animals; ATP Citrate (pro-S)-Lyase; Fatty Acids, Nonesterified; Fatty Liver; Glucose; Homeostasis; Hyperglycemia; Insulin Resistance; Lipid Metabolism; Lipogenesis; Liver; Male; Malonyl Coenzyme A; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Leptin; RNA Interference

2009
An alternative to the glyoxylate shunt.
    Molecular microbiology, 2009, Volume: 73, Issue:6

    Topics: Acetates; Acetyl Coenzyme A; Acyl Coenzyme A; Bacteria; Bicarbonates; Carbon Dioxide; Glyoxylates; Malonyl Coenzyme A; Metabolic Networks and Pathways

2009
Pantothenate kinase from the thermoacidophilic archaeon Picrophilus torridus.
    Journal of bacteriology, 2010, Volume: 192, Issue:1

    Topics: Acetyl Coenzyme A; Amino Acid Sequence; Coenzyme A; Electrophoresis, Polyacrylamide Gel; Genome, Archaeal; Kinetics; Malonyl Coenzyme A; Molecular Sequence Data; Phosphotransferases (Alcohol Group Acceptor); Phylogeny; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Substrate Specificity; Thermoplasmales

2010
Enzymatic total synthesis of rabelomycin, an angucycline group antibiotic.
    Organic letters, 2010, Jun-18, Volume: 12, Issue:12

    Topics: Acetyl Coenzyme A; Anthraquinones; Anti-Bacterial Agents; Catalysis; Malonyl Coenzyme A; Molecular Structure; Polyketide Synthases; Streptomyces

2010
Coenzyme A and its thioester pools in fasted and fed rat tissues.
    Biochemical and biophysical research communications, 2010, Nov-05, Volume: 402, Issue:1

    Topics: Acetyl Coenzyme A; Animals; Brain; Coenzyme A; Eating; Fasting; Female; Male; Malonyl Coenzyme A; Rats; Rats, Wistar; Tissue Distribution

2010
Development and validation of a highly sensitive LC-MS/MS method for simultaneous quantitation of acetyl-CoA and malonyl-CoA in animal tissues.
    Biomedical chromatography : BMC, 2011, Volume: 25, Issue:12

    Topics: Acetonitriles; Acetyl Coenzyme A; Animals; Calibration; Chromatography, Liquid; Drug Stability; Formates; High-Throughput Screening Assays; Linear Models; Liver; Male; Malonyl Coenzyme A; Muscle, Skeletal; Myocardium; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry

2011
Cloning, expression, and enzymatic activity of Acinetobacter baumannii and Klebsiella pneumoniae acetyl-coenzyme A carboxylases.
    Analytical biochemistry, 2011, Oct-01, Volume: 417, Issue:1

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Acinetobacter baumannii; Adenosine Triphosphatases; Biocatalysis; Carbon-Nitrogen Ligases; Cloning, Molecular; Fluorometry; Kinetics; Klebsiella pneumoniae; Malonyl Coenzyme A; Protein Subunits; Recombinant Proteins

2011
Second window of preconditioning normalizes palmitate use for oxidation and improves function during low-flow ischaemia.
    Cardiovascular research, 2011, Dec-01, Volume: 92, Issue:3

    Topics: Acetyl Coenzyme A; Animals; Coronary Circulation; Coronary Stenosis; Disease Models, Animal; Energy Metabolism; Glycolysis; Hemodynamics; Ischemic Preconditioning, Myocardial; Malonyl Coenzyme A; Myocardial Contraction; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardial Stunning; Myocardium; Oxidation-Reduction; Palmitic Acid; Recovery of Function; Sus scrofa; Time Factors; Ventricular Function, Left

2011
Polyketide proofreading by an acyltransferase-like enzyme.
    Chemistry & biology, 2012, Mar-23, Volume: 19, Issue:3

    Topics: Acetyl Coenzyme A; Acyltransferases; Bacillus; Malonyl Coenzyme A; Phylogeny; Polyenes; Polyketides; Pyrans

2012
Effect of diet composition on coenzyme A and its thioester pools in various rat tissues.
    Biochemical and biophysical research communications, 2012, Jul-13, Volume: 423, Issue:4

    Topics: Acetyl Coenzyme A; Animals; Body Weight; Coenzyme A; Diet, High-Fat; Energy Intake; Hypothalamus; Lipid Metabolism; Liver; Male; Malonyl Coenzyme A; Muscle, Skeletal; Obesity; Organ Specificity; Rats; Rats, Wistar; Tissue Distribution; Weight Gain

2012
A type III polyketide synthase from Rhizobium etli condenses malonyl CoAs to a heptaketide pyrone with unusually high catalytic efficiency.
    Molecular bioSystems, 2012, Oct-30, Volume: 8, Issue:12

    Topics: Acetyl Coenzyme A; Amino Acid Sequence; Binding Sites; Catalysis; Malonyl Coenzyme A; Molecular Dynamics Simulation; Polyketide Synthases; Protein Binding; Protein Structure, Secondary; Pyrones; Rhizobium etli; Sequence Alignment; Substrate Specificity

2012
Pressure-overload-induced heart failure induces a selective reduction in glucose oxidation at physiological afterload.
    Cardiovascular research, 2013, Mar-15, Volume: 97, Issue:4

    Topics: Acetyl Coenzyme A; Animals; Echocardiography; Glucose; Glucose Transporter Type 4; Heart Failure; Hypertension; Hypertrophy, Left Ventricular; Lactic Acid; Male; Malonyl Coenzyme A; Mice; Mice, Inbred C57BL; Myocardial Reperfusion Injury; Systole

2013
Metabolic engineering for enhanced fatty acids synthesis in Saccharomyces cerevisiae.
    Metabolic engineering, 2013, Volume: 16

    Topics: Acetyl Coenzyme A; Biofuels; Citric Acid Cycle; Fatty Acids, Unsaturated; Isocitrate Dehydrogenase; Malonyl Coenzyme A; Metabolic Engineering; Multienzyme Complexes; Oxo-Acid-Lyases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins

2013
The yeast AMPK homolog SNF1 regulates acetyl coenzyme A homeostasis and histone acetylation.
    Molecular and cellular biology, 2013, Volume: 33, Issue:23

    Topics: Acetyl Coenzyme A; Acetylation; Acetyltransferases; Chromatin; Coenzyme A Ligases; DNA, Fungal; DNA, Intergenic; Epigenetic Repression; Gene Expression Regulation, Fungal; Gene Knockout Techniques; Histone Acetyltransferases; Histone Deacetylases; Histones; Homeostasis; Malonyl Coenzyme A; Promoter Regions, Genetic; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Saccharomyces cerevisiae; Stress, Physiological

2013
Fatty acid chain elongation in palmitate-perfused working rat heart: mitochondrial acetyl-CoA is the source of two-carbon units for chain elongation.
    The Journal of biological chemistry, 2014, Apr-04, Volume: 289, Issue:14

    Topics: Acetyl Coenzyme A; Animals; Carnitine O-Palmitoyltransferase; Enzyme Inhibitors; Malonyl Coenzyme A; Mitochondria, Heart; Muscle Proteins; Myocardium; Oxidation-Reduction; Palmitic Acid; Palmitoyl Coenzyme A; Perfusion; Rats; Rats, Inbred F344

2014
Enhanced acetyl-CoA production is associated with increased triglyceride accumulation in the green alga Chlorella desiccata.
    Journal of experimental botany, 2015, Volume: 66, Issue:13

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Amino Acid Sequence; Chlorella; Coenzyme A; Gene Expression Regulation, Plant; Malonyl Coenzyme A; Metabolic Networks and Pathways; Molecular Sequence Data; Nitrogen; Plant Proteins; Plastids; Pyruvate Dehydrogenase (Lipoamide); Reference Standards; RNA, Messenger; Starch; Triglycerides

2015
Phosphorylation of Ser-204 and Tyr-405 in human malonyl-CoA decarboxylase expressed in silkworm Bombyx mori regulates catalytic decarboxylase activity.
    Applied microbiology and biotechnology, 2015, Volume: 99, Issue:21

    Topics: Acetyl Coenzyme A; Amino Acid Sequence; Animals; Baculoviridae; Biotransformation; Bombyx; Carboxy-Lyases; DNA Mutational Analysis; Gene Expression; Genetic Vectors; Humans; Kinetics; Malonyl Coenzyme A; Models, Molecular; Molecular Sequence Data; Phosphorylation; Point Mutation; Protein Conformation; Protein Processing, Post-Translational; Recombinant Proteins

2015
Regulating effect of β-ketoacyl synthase domain of fatty acid synthase on fatty acyl chain length in de novo fatty acid synthesis.
    Biochimica et biophysica acta, 2016, Volume: 1861, Issue:3

    Topics: Acetyl Coenzyme A; Binding Sites; Catalysis; Catalytic Domain; Fatty Acid Synthases; Fatty Acids; Malonyl Coenzyme A; Molecular Dynamics Simulation; NADP; Oxidation-Reduction; Protein Binding; Protein Structure, Tertiary; Structure-Activity Relationship; Substrate Specificity

2016
Decreased hepatic contents of coenzyme A molecular species in mice after subchronic mild social defeat stress.
    Stress (Amsterdam, Netherlands), 2016, Volume: 19, Issue:2

    Topics: Acetyl Coenzyme A; Animals; Body Weight; Coenzyme A; Depression; Disease Models, Animal; Down-Regulation; Hypothalamus; Liver; Male; Malonyl Coenzyme A; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Stress, Psychological; Weight Gain

2016
Overexpression of ACC gene from oleaginous yeast Lipomyces starkeyi enhanced the lipid accumulation in Saccharomyces cerevisiae with increased levels of glycerol 3-phosphate substrates.
    Bioscience, biotechnology, and biochemistry, 2016, Volume: 80, Issue:6

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Amino Acid Sequence; Fatty Acids; Fungal Proteins; Gene Expression Regulation, Fungal; Glycerol-3-Phosphate Dehydrogenase (NAD+); Glycerophosphates; Lipid Metabolism; Lipomyces; Malonyl Coenzyme A; Metabolic Engineering; Phylogeny; Real-Time Polymerase Chain Reaction; Saccharomyces cerevisiae; Sequence Alignment; Transgenes

2016
Identification of the active site of human mitochondrial malonyl-coenzyme a decarboxylase: A combined computational study.
    Proteins, 2016, Volume: 84, Issue:6

    Topics: Acetyl Coenzyme A; Carboxy-Lyases; Catalytic Domain; Cyclopropanes; Humans; Malonyl Coenzyme A; Mitochondria; Molecular Docking Simulation; Molecular Dynamics Simulation; Thermodynamics; Thiazoles

2016
Activation of AMP-activated Protein Kinase by Metformin Induces Protein Acetylation in Prostate and Ovarian Cancer Cells.
    The Journal of biological chemistry, 2016, Nov-25, Volume: 291, Issue:48

    Topics: Acetyl Coenzyme A; Acetylation; AMP-Activated Protein Kinases; Female; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Male; Malonyl Coenzyme A; Metformin; Neoplasm Proteins; Ovarian Neoplasms; Prostatic Neoplasms; Protein Processing, Post-Translational

2016
Functional reconstitution of the Mycobacterium tuberculosis long-chain acyl-CoA carboxylase from multiple acyl-CoA subunits.
    The FEBS journal, 2017, Volume: 284, Issue:7

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Bacterial Proteins; Carbon-Carbon Ligases; Cloning, Molecular; Enzyme Assays; Escherichia coli; Gene Expression; Kinetics; Malonyl Coenzyme A; Mycobacterium tuberculosis; Mycolic Acids; Polyketide Synthases; Protein Engineering; Protein Subunits; Recombinant Proteins; Substrate Specificity

2017
Production of 3-hydroxypropionic acid via the malonyl-CoA pathway using recombinant fission yeast strains.
    Journal of bioscience and bioengineering, 2017, Volume: 124, Issue:4

    Topics: Acetyl Coenzyme A; Chloroflexus; Cytosol; Heat-Shock Proteins; Kinesins; Lactic Acid; Malonyl Coenzyme A; Oxidoreductases; Promoter Regions, Genetic; Schizosaccharomyces; Schizosaccharomyces pombe Proteins

2017
Structural and Functional Studies of the Daunorubicin Priming Ketosynthase DpsC.
    ACS chemical biology, 2018, 01-19, Volume: 13, Issue:1

    Topics: Acetyl Coenzyme A; Acylation; Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Daunorubicin; Malonyl Coenzyme A; Models, Molecular; Polyketide Synthases; Protein Conformation; Streptomyces

2018
Cytosolic reverse CrAT activity in cardiac tissue: potential importance for fuel selection.
    The Biochemical journal, 2018, 04-09, Volume: 475, Issue:7

    Topics: Acetyl Coenzyme A; Carnitine O-Acetyltransferase; Carnitine O-Palmitoyltransferase; Cytosol; Energy Metabolism; Malonyl Coenzyme A

2018
Metabolic reprogramming enables hepatocarcinoma cells to efficiently adapt and survive to a nutrient-restricted microenvironment.
    Cell cycle (Georgetown, Tex.), 2018, Volume: 17, Issue:7

    Topics: Acetyl Coenzyme A; Adaptation, Physiological; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Survival; Citric Acid; Citric Acid Cycle; Fatty Acids; Gene Expression Regulation, Neoplastic; Glucose; Glucose Transporter Type 1; Glycolysis; Hep G2 Cells; Hexokinase; Humans; L-Lactate Dehydrogenase; Lipid Metabolism; Liver Neoplasms; Malonyl Coenzyme A; Mice; Signal Transduction; Survival Analysis; Triglycerides

2018
Overexpression of acetyl-CoA carboxylase in Aspergillus terreus to increase lovastatin production.
    New biotechnology, 2018, Sep-25, Volume: 44

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Aspergillus; Fungal Proteins; Lovastatin; Malonyl Coenzyme A

2018
Modular pathway engineering for resveratrol and piceatannol production in engineered Escherichia coli.
    Applied microbiology and biotechnology, 2018, Volume: 102, Issue:22

    Topics: Acetyl Coenzyme A; Biosynthetic Pathways; Escherichia coli; Escherichia coli Proteins; Malonyl Coenzyme A; Metabolic Engineering; Resveratrol; Stilbenes

2018
Biochemical characterization of the minimal domains of an iterative eukaryotic polyketide synthase.
    The FEBS journal, 2018, Volume: 285, Issue:23

    Topics: Acetyl Coenzyme A; Acylation; Animals; Catalytic Domain; Ducks; Kinetics; Malonyl Coenzyme A; Phylogeny; Polyketide Synthases; Protein Domains; Substrate Specificity

2018
Increased sesqui- and triterpene production by co-expression of HMG-CoA reductase and biotin carboxyl carrier protein in tobacco (Nicotiana benthamiana).
    Metabolic engineering, 2019, Volume: 52

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Carrier Proteins; Cytosol; Fatty Acid Synthase, Type II; Fatty Acids; Hydroxymethylglutaryl CoA Reductases; Malonyl Coenzyme A; Monocyclic Sesquiterpenes; Nicotiana; Plant Leaves; Sesquiterpenes; Triterpenes

2019
Enhancing 3-hydroxypropionic acid production in combination with sugar supply engineering by cell surface-display and metabolic engineering of Schizosaccharomyces pombe.
    Microbial cell factories, 2018, Nov-13, Volume: 17, Issue:1

    Topics: Acetyl Coenzyme A; Batch Cell Culture Techniques; Carbon; Lactic Acid; Malonyl Coenzyme A; Metabolic Engineering; Metabolic Networks and Pathways; Oxidoreductases; Schizosaccharomyces; Sugars

2018
Improved lovastatin production by inhibiting (+)-geodin biosynthesis in Aspergillus terreus.
    New biotechnology, 2019, Sep-25, Volume: 52

    Topics: Acetyl Coenzyme A; Aspergillus; Benzofurans; Biosynthetic Pathways; Glycerol; Lactose; Lovastatin; Malonyl Coenzyme A

2019
Transfer of glucose hydrogens via acetyl-CoA, malonyl-CoA, and NADPH to fatty acids during de novo lipogenesis.
    Journal of lipid research, 2019, Volume: 60, Issue:12

    Topics: Acetyl Coenzyme A; Animals; Fatty Acids; Glucose; Hydrogen; Lipogenesis; Male; Malonyl Coenzyme A; Mice; Mice, Inbred C57BL; NADP

2019
Model-Assisted Fine-Tuning of Central Carbon Metabolism in Yeast through dCas9-Based Regulation.
    ACS synthetic biology, 2019, 11-15, Volume: 8, Issue:11

    Topics: Acetyl Coenzyme A; Biosensing Techniques; Carbon; Computer Simulation; CRISPR-Associated Protein 9; Cytosol; Ethanol; Gene Expression Regulation, Fungal; Genes, Fungal; Glucose; Malonyl Coenzyme A; Metabolic Engineering; Metabolic Flux Analysis; RNA, Guide, Kinetoplastida; Saccharomyces cerevisiae; Synthetic Biology; Transcription, Genetic

2019
Dietary branched-chain amino acid restriction alters fuel selection and reduces triglyceride stores in hearts of Zucker fatty rats.
    American journal of physiology. Endocrinology and metabolism, 2020, 02-01, Volume: 318, Issue:2

    Topics: Acetyl Coenzyme A; Amino Acids, Branched-Chain; Animals; Diet; Glucose; Male; Malonyl Coenzyme A; Metabolomics; Myocardium; Obesity; Palmitates; Protein Kinases; Rats; Rats, Zucker; Triglycerides

2020
A Simple and Direct Assay for Monitoring Fatty Acid Synthase Activity and Product-Specificity by High-Resolution Mass Spectrometry.
    Biomolecules, 2020, 01-10, Volume: 10, Issue:1

    Topics: Acetyl Coenzyme A; Animals; Cattle; Enzyme Assays; Fatty Acid Synthase, Type I; Lipidomics; Malonyl Coenzyme A; Mass Spectrometry; NADP; Substrate Specificity

2020
Tartronic acid promotes de novo lipogenesis and inhibits CPT-1β by upregulating acetyl-CoA and malonyl-CoA.
    Life sciences, 2020, Oct-01, Volume: 258

    Topics: 3T3-L1 Cells; Acetyl Coenzyme A; Animals; Carnitine O-Palmitoyltransferase; Diet, High-Fat; Lipogenesis; Male; Malonyl Coenzyme A; Mice; Mice, Inbred C57BL; Tartronates; Up-Regulation

2020
Ustethylin Biosynthesis Implies Phenethyl Derivative Formation in
    Organic letters, 2020, 10-16, Volume: 22, Issue:20

    Topics: Acetyl Coenzyme A; Aspergillus; Malonyl Coenzyme A; Methyltransferases; Molecular Structure; Oxidoreductases; Polyketide Synthases

2020
Applied evolution: Dual dynamic regulations-based approaches in engineering intracellular malonyl-CoA availability.
    Metabolic engineering, 2021, Volume: 67

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Malonyl Coenzyme A; Metabolic Engineering; Polyketides

2021
Increasing Lovastatin Production by Re-routing the Precursors Flow of Aspergillus terreus via Metabolic Engineering.
    Molecular biotechnology, 2022, Volume: 64, Issue:1

    Topics: Acetyl Coenzyme A; Aspergillus; Benzofurans; Biosynthetic Pathways; Fermentation; Glycerol; Kinetics; Lactose; Lovastatin; Malonyl Coenzyme A; Metabolic Engineering

2022
Paradoxical activation of transcription factor SREBP1c and de novo lipogenesis by hepatocyte-selective ATP-citrate lyase depletion in obese mice.
    The Journal of biological chemistry, 2022, Volume: 298, Issue:10

    Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Animals; ATP Citrate (pro-S)-Lyase; Diabetes Mellitus, Type 2; Hepatocytes; Lipogenesis; Liver; Malonyl Coenzyme A; Mice; Mice, Obese; Palmitates; Sterol Regulatory Element Binding Protein 1

2022
Targeting peroxisomal fatty acid oxidation improves hepatic steatosis and insulin resistance in obese mice.
    The Journal of biological chemistry, 2023, Volume: 299, Issue:2

    Topics: Acetyl Coenzyme A; Acetylcarnitine; Animals; Diabetes Mellitus, Experimental; Fatty Acids; Fatty Liver; Insulin Resistance; Liver; Malonyl Coenzyme A; Mice; Mice, Obese; Obesity; Oxidation-Reduction

2023
Direct Utilization of Peroxisomal Acetyl-CoA for the Synthesis of Polyketide Compounds in
    ACS synthetic biology, 2023, 06-16, Volume: 12, Issue:6

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Malonyl Coenzyme A; Polyketides; Saccharomyces cerevisiae

2023
Quantitative Analysis of Acetyl-CoA, Malonyl-CoA, and Succinyl-CoA in Myocytes.
    Journal of the American Society for Mass Spectrometry, 2023, Nov-01, Volume: 34, Issue:11

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Humans; Malonyl Coenzyme A; Muscle Cells

2023