acetyl coenzyme a has been researched along with malonyl coenzyme a in 181 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 64 (35.36) | 18.7374 |
1990's | 32 (17.68) | 18.2507 |
2000's | 37 (20.44) | 29.6817 |
2010's | 36 (19.89) | 24.3611 |
2020's | 12 (6.63) | 2.80 |
Authors | Studies |
---|---|
Fitzgerald, V; Rock, CO; Snyder, F | 1 |
Rous, S | 1 |
Labadie, P | 1 |
Engeser, H; Lynen, F; Wieland, F | 1 |
Giompres, P; Packter, NM | 1 |
Ferrick, TJ; Ness, GC; Porter, JW; Slakey, LL | 1 |
Holland, R; Roughan, PG; Slack, CR | 1 |
Kishimoto, Y; Murad, S | 1 |
Kariya, T; Wille, LJ | 1 |
Dhopeshwarkar, GA; Elepano, MG; Mead, JF | 1 |
Kikuchi, S; Kolattukudy, PE | 1 |
Jordan, PM; Spencer, JB | 1 |
Kikuchi, S; Kolattukudy, PE; Rainwater, DL | 1 |
Dickson, AC; Koeppen, AH; Riley, KM | 1 |
Cronan, JE; Jackowski, S; Murphy, CM; Rock, CO | 1 |
Horie, S; Suga, T; Suzuki, T | 1 |
Fukuda, H; Iritani, N; Katsurada, A | 1 |
Claeys, A; De Spiegeleer, B; Mannens, G; Slegers, G; Van den Bossche, W | 1 |
Wakil, SJ | 1 |
Denisenko, TV; Dizhe, EB; Klimov, AN; Poliakova, ED; Vasil'eva, LE | 1 |
Buckley, MG; Rath, EA | 1 |
Nomura, G; Takamura, Y | 1 |
Gaucher, GM; Lam, KS; Neway, JO | 1 |
Ikai, A; Morishima, N | 1 |
Jackowski, S; Rock, CO | 1 |
Engel, AG; Zierz, S | 1 |
Aoyama, H; Nakatani, T; Sato, T; Siegel, JH; Vary, TC | 1 |
Gilbert, HF; Walters, DW | 1 |
Knudsen, J; Mikkelsen, J; Smith, S | 1 |
Højrup, P; Knudsen, J; Mikkelsen, J; Rasmussen, MM; Roepstorff, P | 1 |
Cassagne, C; Heape, MA; Sargueil-Boiron, F | 1 |
Arakawa, A; Kitayama, Y; Ogawa, Y; Takamura, Y; Tosaki, M; Yamanaka, S | 1 |
Anderson, VE; Hammes, GG | 1 |
Hansen, HF; Hansen, JK; Højrup, P; Knudsen, J; Mikkelsen, J | 1 |
Bar-Tana, J; Rose-Kahn, G | 1 |
Jilka, JM; Kazemi, M; Rahmatullah, M; Roche, TE | 1 |
Ohashi, K; Otsuka, H; Seyama, Y | 1 |
Linn, T; Smith, S; Stern, A | 1 |
Bird, MI; Edwards, MR; Saggerson, ED | 1 |
Knudsen, J; Mikkelsen, J; Smith, S; Stern, A | 1 |
Jones, CT; Wahle, KW | 1 |
Denisenko, TV; Dizhe, EB; Klimova, TA; Poliakova, ED; Vasil'eva, LE | 2 |
Inui, H; Kitaoka, S; Miyatake, K; Nakano, Y | 1 |
Foster, DW; McGarry, JD | 1 |
Cinti, DL; Cook, L; Prasad, MR; Vieth, R | 1 |
Brown, GK; Scholem, RD | 1 |
Koeppen, AH; Mitzen, EJ | 1 |
Tsao, MU | 1 |
Hardie, DG; McCarthy, AD | 1 |
McCormick, K; Notar-Francesco, VJ; Sriwatanakul, K | 1 |
Dizhe, EB; Klimov, AN; Klimova, TA; Poliakova, ED; Vasil'eva, LE | 1 |
Hsu, RY; Sheplock, GJ; Soulié, JM; Tian, WX | 1 |
Borrebaek, B; Bremer, J; Singh, B; Stakkestad, JA | 1 |
Ernst-Fonberg, ML; Jonak, ZL; Walker, TA; Worsham, LM | 1 |
Katiyar, SS; Pan, D; Porter, JW | 1 |
Arai, K; Kawaguchi, A; Koike, N; Okuda, S; Saito, Y; Seyama, Y; Yamakawa, T | 1 |
Benveniste, J; Mencia-Huerta, JM; Morgat, JL; Roubin, R | 1 |
Denisenko, TV; Dizhe, EB; Klimov, AN; Klimova, TA; Petrova, LA; Poliakova, ED; Vasil'eva, LE | 1 |
Kumar, S; Srinivasan, KR | 2 |
Linn, TC; Srere, PA; Stark, MJ | 1 |
Grunnet, I; Knudsen, J | 1 |
Arai, K; Kawaguchi, A; Okuda, S; Seyama, Y; Yamakawa, T | 1 |
Cinti, DL; Keyes, SR | 1 |
Kurosaki, F | 3 |
Corkey, BE; Curtiss, D; Kilpatrick, L; Nachiappan, V | 1 |
Heath, RJ; Rock, CO | 1 |
Gamble, J; Lopaschuk, GD | 1 |
Barr, A; Barr, R; Itoi, T; Lopaschuk, GD; Witters, LA | 1 |
Gulliver, BS; Slabas, AR | 1 |
Hutchinson, CR; Shen, B | 1 |
Cane, DE | 1 |
Aparicio, JF; Caffrey, P; Leadlay, PF; Loughran, MS; Marsden, AF; Staunton, J | 1 |
Ikai, A | 1 |
Falk, KL; Guerra, DJ | 1 |
Allard, MF; Lopaschuk, GD; Schönekess, BO | 1 |
Bhogal, P; Child, CJ; Shoolingin-Jordan, PM; Spencer, JB | 1 |
Rangan, VS; Smith, S | 2 |
Chohnan, S; Fujio, T; Furukawa, H; Nishihara, H; Takamura, Y | 1 |
Laugier, C; Pacheco, H; Pageaux, JF | 1 |
Roughan, PG | 1 |
Kawaguchi, A; Kondo, K; Watanabe, K; Yazawa, K | 1 |
Child, CJ; Shoolingin-Jordan, PM | 1 |
Katiyar, SS; Mukherjee, S | 1 |
Chohnan, S; Izawa, H; Nishihara, H; Takamura, Y | 1 |
Hunter, SC; Ohlrogge, JB | 1 |
An, JH; Kim, YS | 1 |
Joshi, AK; Rangan, VS; Smith, S | 1 |
Bauer, Z; Fuchs, G; Gad'on, N; Huber, H; Menendez, C; Stetter, KO | 1 |
Bowman, ME; Dixon, RA; Ferrer, JL; Jez, JM; Noel, JP | 1 |
Heigenhauser, GJ; Howlett, RA; Spriet, LL; Starritt, EC | 1 |
Kealey, JT; Khosla, C; Pohl, NL; Richardson, MT | 1 |
Kerr, RG; Wen, J | 1 |
Bartlett, K; Eaton, S; Fukumoto, K; Paladio Duran, N; Pierro, A; Quant, PA; Spitz, L | 1 |
Allard, MF; Barr, RL; Longnus, SL; Lopaschuk, GD; Wambolt, RB | 1 |
Florova, G; Kazanina, G; Reynolds, KA | 1 |
Bouchard, B; Brunengraber, H; Des Rosiers, C; Kelleher, JK; Poirier, M; Reszko, AE; Vincent, G | 1 |
Cane, DE; Khosla, C; Lau, J; Liou, GF | 1 |
Fuchs, G; Hügler, M; Jahn, M; Krieger, RS | 1 |
Fukuzawa, H; Kajikawa, M; Kanamaru, H; Ohyama, K; Sakuradani, E; Shimizu, S; Yamaoka, S; Yamato, KT | 1 |
Ahmed, S; Bassilian, S; Boren, J; Boros, LG; Cascante, M; Centelles, JJ; Lee, WN; Lim, S | 1 |
SAUER, F | 1 |
HUELSMANN, WC | 1 |
Schofield, CJ; Sleeman, MC | 1 |
Kelleher, NL; McLoughlin, SM; Tseng, CC; Walsh, CT | 1 |
Abe, I; Noguchi, H; Oguro, S; Utsumi, Y | 1 |
Glickman, JF; Weiss, DR | 1 |
Arrhenius, T; Barr, R; Brown, S; Chandler, MP; Cheng, JF; Dyck, JR; Harmon, C; Lopaschuk, GD; Nadzan, AM; Stanley, WC; Wallace, D; Yang, G | 1 |
Bartram, S; Falk, KL; Gershenzon, J; Hick, A; Pickett, JA; Textor, S; Vogel, C | 1 |
Brunengraber, H; Cheng, JF; David, F; Des Rosiers, C; Diaz, M; Dyck, JR; Jobbins, KA; Kasumov, T; Lopaschuk, GD; Reszko, AE; Stanley, WC; Thomas, KR | 1 |
Bederman, IR; Brunengraber, H; David, F; Kasumov, T; Kelleher, JK; Reszko, AE | 1 |
Halberg, N; Hillig, T; Kiens, B; Richter, EA; Roepstorff, C; Ruderman, NB; Saha, AK; Wojtaszewski, JF | 1 |
Astrup, AV; Buemann, B | 1 |
Brock, M; Keller, NP; Zhang, YQ | 1 |
Bian, F; Brunengraber, H; David, F; Hoppel, CL; Jobbins, KA; Kasumov, T; Minkler, PE; Thomas, KR | 1 |
Cheng, D; Rendina, AR | 1 |
Adams, JE; Bian, F; Brunengraber, H; David, F; Hoppel, CL; Jobbins, KA; Kasumov, T; Minkler, PE; Thomas, KR | 1 |
Griffin, MJ; Sul, HS | 1 |
Choi, CS; Cline, GW; Coleman, RA; Hammond, LE; Liu, ZX; Morino, K; Neschen, S; Pongratz, RL; Romanelli, AJ; Shulman, GI; Zhang, D; Zhang, XM | 1 |
Anderson, VE; Bian, F; Brunengraber, H; Hoppel, CL; Jobbins, KA; Kasumov, T; Kerner, J; Minkler, PE | 1 |
Hayashi, O; Satoh, K | 2 |
Onay-Besikci, A; Sambandam, N | 1 |
Amills, M; Ares, JL; Badaoui, B; Carrizosa, J; Jordana, J; Sànchez, A; Serradilla, JM; Tomàs, A; Urrutia, B | 1 |
Burns, DJ; Camp, HS; Cheng, X; Chiou, W; Gao, L; Tang, H | 1 |
Geders, TW; Gerwick, WH; Gu, L; Håkansson, K; Sherman, DH; Smith, JL; Wang, B | 1 |
Lantz, AE; Nielsen, J; Nielsen, ML; Wattanachaisaereekul, S | 1 |
Gao, X; Jiang, L; Li, S; Li, W; Liu, Y; Rui, L; Wang, J; Wang, Q; You, J; Yu, Y; Zeng, R | 1 |
Schink, B | 1 |
Chohnan, S; Hanada, S; Jackowski, S; Leonardi, R; Miyamoto, Y; Takagi, M; Tamaki, H | 1 |
Kharel, MK; Lian, H; Pahari, P; Rohr, J | 1 |
Chohnan, S; Katoh, H; Onizawa, N; Tokutake, Y; Toyoda, A | 1 |
Gilibili, RR; Giri, S; Kandaswamy, M; Mullangi, R; Rajagopal, S; Sharma, K | 1 |
Alves, J; Harris, JL; Peters, EC; Trauger, JW; Westling, L | 1 |
Fasano, M; Fischer, SK; Kudej, RK; Lewandowski, ED; Lopaschuk, GD; Vatner, DE; Vatner, SF; Zhao, X | 1 |
Brendel, N; Frank, S; Hertweck, C; Jensen, K; Kohlhaas, C; Moldenhauer, J; Niederkrüger, H; Oldiges, M; Piel, J; Pöplau, P; Townsend, CA; Vagstad, AL; Zimmermann, K | 1 |
Chohnan, S; Iio, W; Kohari, D; Ogata, Y; Onizawa, N; Tokutake, Y; Toyoda, A | 1 |
Jeya, M; Kim, TS; Kumar Tiwari, M; Lee, JK; Li, J; Zhao, H | 1 |
Basu, R; Clanachan, A; Gandhi, M; Kassiri, Z; Lopaschuk, GD; Mori, J; Oudit, GY; Zhabyeyev, P | 1 |
Chen, WN; Feng, H; Tang, X | 1 |
Galdieri, L; Vancura, A; Zhang, M | 1 |
Hoppel, CL; Kerner, J; Lesnefsky, EJ; Minkler, PE | 1 |
Davaapil, H; Gout, I; Tsuchiya, Y | 1 |
Lian, J; Zhao, H | 1 |
Avidan, O; Brandis, A; Pick, U; Rogachev, I | 1 |
Chung, SK; Hwang, IW; Kato, T; Makishima, Y; Park, EY; Park, S; Suzuki, T; Terzic, A | 1 |
Cui, W; Ji, M; Liang, Y; Ma, X; Tian, W | 1 |
Chohnan, S; Goto, T; Hagiya, Y; Kubota, Y; Toyoda, A | 1 |
Haque, ME; Liu, A; Wang, J; Wang, R; Xu, R | 1 |
Bi, S; Li, X; Ling, B; Liu, Y; Wang, Z | 1 |
Galdieri, L; Gatla, H; Vancura, A; Vancurova, I | 1 |
Bardou, F; Bazet Lyonnet, B; Diacovich, L; Gago, G; Gramajo, H; Lemassu, A; Quémard, A; Spina, L | 1 |
Kondo, A; Matsumoto, T; Tanaka, T | 1 |
Higuchi, Y; Maeda, Y; Suyama, A; Takegawa, K; Urushihara, M | 1 |
Crosby, J; Crump, MP; Jackson, DR; Milligan, JC; Mohammed, LY; Patel, AB; Shakya, G; Tsai, SC; Valentic, TR; Vasilakis, K; Wattana-Amorn, P | 1 |
Holloway, GP; Petrick, HL | 1 |
Bilodeau, M; Cassim, S; Dehbidi-Assadzadeh, L; Lapierre, P; Raymond, VA | 1 |
Abbas, A; Abd Rahim, MH; Campbell, L; Carter, D; Hasan, H; Montoya, A | 3 |
Chu, LL; Dhakal, D; Pandey, RP; Pokhrel, AR; Shrestha, A; Sohng, JK | 1 |
Altabe, S; Arabolaza, A; Comba, S; Gramajo, H; Labadie, GR; Recio-Balsells, AI; Sabatini, M; Takano, E | 1 |
Kang, MK; Kim, J; Kim, SU; Kwon, M; Lee, AR; Ro, DK | 1 |
Hirata, Y; Kishida, M; Kondo, A; Konishi, R; Matsumoto, T; Otomo, C; Ozaki, A; Takayama, S; Tanaka, T | 1 |
Belew, GD; Jones, JG; Macedo, MP; Oliveira, PJ; Rito, J; Silva, J; Tavares, L; Teixeira, J; Viegas, I | 1 |
David, F; Ferreira, R; Hedin, A; Nielsen, J; Sánchez, BJ; Siewers, V; Skrekas, C | 1 |
Christopher, BA; Deleye, Y; Ilkayeva, O; McGarrah, RW; Newgard, CB; Page, S; Walejko, JM; White, PJ; Zhang, GF | 1 |
Ejsing, CS; Martínez-Montañés, F; Topolska, M | 1 |
Marienhagen, J; Milke, L | 1 |
Gu, Y; Ma, J; Marsafari, M; Xu, P | 1 |
Huang, K; Li, X; Shi, X; Wang, J; Yang, G; Zhang, D; Zhou, X | 1 |
Fan, A; Li, SM; Wang, H; Yang, Y; Zhang, L; Zheng, L | 1 |
Ding, S; Dong, M; Duan, X; Fan, X; Liu, S; Pablo, CM; Peng, H; Wu, J; Zhou, J; Zhou, L; Zhuang, Q | 1 |
Czech, MP; DiMarzio, C; Friedline, RH; Gao, G; Han, X; He, W; Herman, MA; Ilkayeva, OR; Kelly, M; Kim, JK; Lifshitz, L; Min, K; Newgard, CB; Pan, M; Raymond, N; Rowland, L; Wetoska, N; Xie, J; Yenilmez, B; Zhang, GF | 1 |
Chen, X; Li, P; Shang, L; Wang, Y; Yao, H; Zeng, J; Zhang, X | 1 |
Bai, Z; Fu, Z; Li, Y; Lin, P; Liu, C; Liu, X; Yang, Y | 1 |
Karlstaedt, A; Lorenzi, PL; Martinez, SA; Tan, L | 1 |
11 review(s) available for acetyl coenzyme a and malonyl coenzyme a
Article | Year |
---|---|
The relationship between structure and function for and the regulation of the enzymes of fatty acid synthesis.
Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Animals; Enzyme Activation; Fatty Acid Synthases; Fatty Acids; Ligases; Liver; Macromolecular Substances; Malonyl Coenzyme A; Structure-Activity Relationship | 1986 |
Regulation of hepatic fatty acid oxidation and ketone body production.
Topics: Acetyl Coenzyme A; Adipose Tissue; Animals; Carnitine; Carnitine Acyltransferases; Fatty Acids; Fatty Acids, Nonesterified; Glucagon; Glycogen; Insulin; Ketone Bodies; Liver; Malonyl Coenzyme A; Meglutol; Models, Biological; Triglycerides | 1980 |
The 1993 Merck Frosst Award. Acetyl-CoA carboxylase: an important regulator of fatty acid oxidation in the heart.
Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Animals; Carbohydrate Metabolism; Carnitine; Carnitine O-Palmitoyltransferase; Diabetes Mellitus; Down-Regulation; Fatty Acids; Humans; Malonyl Coenzyme A; Mitochondria, Heart; Myocardial Ischemia; Oxidation-Reduction | 1994 |
[Fatty acid synthetase].
Topics: Acetyl Coenzyme A; Animals; Chemical Phenomena; Chemistry, Physical; Fatty Acid Synthases; Fatty Acids; Macromolecular Substances; Malonyl Coenzyme A | 1993 |
Carnitine palmitoyl transferase I and the control of myocardial beta-oxidation flux.
Topics: Acetyl Coenzyme A; Animals; Biological Transport; Carnitine O-Palmitoyltransferase; Humans; Isoenzymes; Kinetics; Malonyl Coenzyme A; Mitochondria, Heart; Myocardium; Oxidation-Reduction | 2001 |
Insulin regulation of fatty acid synthase gene transcription: roles of USF and SREBP-1c.
Topics: Acetyl Coenzyme A; Animals; CCAAT-Enhancer-Binding Proteins; DNA-Binding Proteins; Fatty Acid Synthases; Gene Expression Regulation, Enzymologic; Glucose; Humans; Insulin; Malonyl Coenzyme A; Mice; Models, Biological; Palmitic Acid; Promoter Regions, Genetic; Protein Binding; Rats; RNA, Messenger; Sterol Regulatory Element Binding Protein 1; Time Factors; Transcription Factors; Transcription, Genetic; Upstream Stimulatory Factors | 2004 |
Signalling functions of coenzyme A and its derivatives in mammalian cells.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Coenzyme A; Malonyl Coenzyme A; Mammals; Signal Transduction | 2014 |
Recent advances in biosynthesis of fatty acids derived products in Saccharomyces cerevisiae via enhanced supply of precursor metabolites.
Topics: Acetyl Coenzyme A; Fatty Acids; Fatty Acids, Nonesterified; Humans; Malonyl Coenzyme A; Metabolic Engineering; Saccharomyces cerevisiae | 2015 |
Engineering metabolic pathways in Escherichia coli for constructing a "microbial chassis" for biochemical production.
Topics: Acetyl Coenzyme A; Escherichia coli; Malonyl Coenzyme A; Metabolic Engineering; Metabolic Networks and Pathways; Shikimic Acid | 2017 |
Engineering intracellular malonyl-CoA availability in microbial hosts and its impact on polyketide and fatty acid synthesis.
Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Biofuels; Directed Molecular Evolution; Fatty Acids; Intracellular Space; Malonyl Coenzyme A; Metabolic Engineering; Polyketides | 2020 |
Synthetic biology, systems biology, and metabolic engineering of Yarrowia lipolytica toward a sustainable biorefinery platform.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Fatty Acids; Lipids; Malonyl Coenzyme A; Metabolic Engineering; Polyketides; Synthetic Biology; Systems Biology; Terpenes; Yarrowia | 2020 |
170 other study(ies) available for acetyl coenzyme a and malonyl coenzyme a
Article | Year |
---|---|
Coupling of the biosynthesis of fatty acids and fatty alcohols.
Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Animals; Cell-Free System; Detergents; Fatty Acid Synthases; Fatty Alcohols; Harderian Gland; Lacrimal Apparatus; Malonyl Coenzyme A; Microsomes; NADP; Rabbits; Trypsin | 1978 |
Possible contribution of [2-3H]malate and [2, 3-3h]succinate tritium to the same tritiated NADPH pool for participation in fatty acid synthesis.
Topics: Acetates; Acetyl Coenzyme A; Animals; Fatty Acid Synthases; Fatty Acids; Hydroxybutyrates; Lactates; Liver; Malates; Male; Malonyl Coenzyme A; Mice; NADP; Succinates; Tritium | 1978 |
[Microsomal biogenesis of fatty acids by condensation of carrier proteins and a multi-enzymatic complex].
Topics: Acetyl Coenzyme A; Acyl Carrier Protein; Alcohol Oxidoreductases; Enzyme Precursors; Fatty Acid Synthases; Fatty Acids; Keto Acids; Malonyl Coenzyme A; Microsomes; Models, Biological; NADP | 1978 |
Localization of three non-thiol binding sites on polypeptide chain beta of yeast fatty acid synthetase.
Topics: Acetyl Coenzyme A; Binding Sites; Dithionitrobenzoic Acid; Fatty Acid Synthases; Macromolecular Substances; Malonyl Coenzyme A; Nitrobenzoates; Palmitoyl Coenzyme A; Saccharomyces cerevisiae | 1977 |
Purification and properties of the polymeric fatty acid synthetase from a filamentous fungus.
Topics: Acetyl Coenzyme A; Aspergillus fumigatus; Cold Temperature; Fatty Acid Synthases; Kinetics; Malonyl Coenzyme A; Microscopy, Electron; Molecular Weight; Protein Conformation | 1978 |
De novo fatty acid synthesis and fatty acid elongation catalyzed by subcellular fractions from hog and human aorta.
Topics: Acetyl Coenzyme A; Animals; Aorta; Coenzyme A; Fatty Acid Synthases; Fatty Acids; Humans; Malonyl Coenzyme A; Species Specificity; Subcellular Fractions; Swine | 1979 |
On the control of long-chain-fatty acid synthesis in isolated intact spinach (Spinacia oleracea) chloroplasts.
Topics: Acetates; Acetyl Coenzyme A; Acyl Carrier Protein; Bicarbonates; Buffers; Chloroplasts; Fatty Acids; In Vitro Techniques; Kinetics; Malonyl Coenzyme A | 1979 |
Chain elongation of fatty acid in brain: a comparison of mitochondrial and microsomal enzyme activities.
Topics: Acetyl Coenzyme A; Aging; Animals; Brain; Fatty Acid Synthases; Fatty Acids; Malonyl Coenzyme A; Mice; Mice, Quaking; Microsomes; Mitochondria; Mutation; Myelin Sheath; Rats | 1978 |
Inhibition of fatty acid synthesis by RMI 14,514 (5-tetradecyloxy-2-furoic acid).
Topics: Acetyl Coenzyme A; Animals; Carboxylic Acids; Fatty Acids; Furans; Kinetics; Liver; Male; Malonyl Coenzyme A; Rats | 1978 |
Transformations of the polyunsaturated fatty acids in the brain.
Topics: Acetyl Coenzyme A; Animals; Binding, Competitive; Brain; Fatty Acid Synthases; Fatty Acids, Unsaturated; Kinetics; Malonyl Coenzyme A; Microsomes; Mitochondria; Rats | 1977 |
Immobilization of fatty acid synthetase from Mycobacterium smegmatis by radiation-induced polymerization.
Topics: Acetyl Coenzyme A; Chromatography, Gas; Cross-Linking Reagents; Enzyme Stability; Enzymes, Immobilized; Fatty Acid Synthases; Fluorescent Antibody Technique; Hydrogen-Ion Concentration; Malonyl Coenzyme A; Methacrylates; Mycobacterium; Polymers; Temperature | 1990 |
Investigation of the mechanism and steric course of the reaction catalyzed by 6-methylsalicylic acid synthase from Penicillium patulum using (R)-[1-13C;2-2H]- and (S)-[1-13C;2-2H]malonates.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Acyltransferases; Ligases; Malonates; Malonyl Coenzyme A; Mass Spectrometry; Multienzyme Complexes; Oxidoreductases; Penicillium; Stereoisomerism | 1992 |
Purification and characterization of an unusually large fatty acid synthase from Mycobacterium tuberculosis var. bovis BCG.
Topics: Acetyl Coenzyme A; Amino Acids; Blotting, Western; Coenzyme A; Electrophoresis, Polyacrylamide Gel; Fatty Acid Synthases; Hydrogen-Ion Concentration; Malonyl Coenzyme A; Mycobacterium; Mycobacterium bovis; Substrate Specificity | 1992 |
The origin of free brain malonate.
Topics: Acetates; Acetic Acid; Acetyl Coenzyme A; Aging; Animals; Brain; Butyrates; Butyric Acid; Carbon Radioisotopes; Glutamates; Glutamic Acid; Kinetics; Malonates; Malonyl Coenzyme A; Rats | 1991 |
Acetoacetyl-acyl carrier protein synthase. A target for the antibiotic thiolactomycin.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Acetyl Coenzyme A; Acyl Carrier Protein; Acyltransferases; Drug Resistance, Microbial; Escherichia coli; Fatty Acids; Kinetics; Lactones; Malonyl Coenzyme A; Thiophenes | 1989 |
Existence of acetyl-CoA-dependent chain elongation system in hepatic peroxisomes of rat: effects of clofibrate and di-(2-ethylhexyl)phthalate on the activity.
Topics: Acetyl Coenzyme A; Acyl-CoA Dehydrogenases; Animals; Cell Fractionation; Centrifugation, Density Gradient; Clofibrate; Diethylhexyl Phthalate; Fatty Acid Desaturases; Fatty Acids; Kinetics; Liver; Male; Malonyl Coenzyme A; Microbodies; Phthalic Acids; Rats; Rats, Inbred Strains; Reference Values | 1989 |
Effects of dietary nutrients on substrate and effector levels of lipogenic enzymes, and lipogenesis from tritiated water in rat liver.
Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Animals; Cyclic AMP; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Fatty Acid Synthases; Fatty Acids; Glucagon; Glucosephosphate Dehydrogenase; Insulin; Liver; Male; Malonyl Coenzyme A; Rats; Rats, Inbred Strains; Tritium | 1986 |
Direct assay for phosphotransacetylase and acetyl-coenzyme A carboxylase by high-performance liquid chromatography.
Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Acetyltransferases; Animals; Chromatography, High Pressure Liquid; Ligases; Malonyl Coenzyme A; Phosphate Acetyltransferase | 1986 |
[Formation of mevalonic acid, sterols and bile acids from [1-14C]acetyl-CoA and [2-14C]malonyl-CoA in the liver of rabbits with experimental hypercholesterolemia].
Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Animals; Bile Acids and Salts; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent; Hypercholesterolemia; Liver; Malonyl Coenzyme A; Mevalonic Acid; Rabbits; Sterols; Substrate Specificity | 1987 |
Regulation of fatty acid synthesis and malonyl-CoA content in mouse brown adipose tissue in response to cold-exposure, starvation or re-feeding.
Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Acyl Coenzyme A; Adipose Tissue, Brown; Animals; Blood Glucose; Citrates; Cold Temperature; Fatty Acid Synthases; Fatty Acids; Female; Food; Malonyl Coenzyme A; Mice; Starvation | 1987 |
Changes in the intracellular concentration of acetyl-CoA and malonyl-CoA in relation to the carbon and energy metabolism of Escherichia coli K12.
Topics: Acetyl Coenzyme A; Carbon; Culture Media; Energy Metabolism; Escherichia coli; Glucose; Malonyl Coenzyme A | 1988 |
In vitro stabilization of 6-methylsalicylic acid synthetase from Penicillium urticae.
Topics: Acetyl Coenzyme A; Acyltransferases; Ascorbic Acid; Dithiothreitol; Drug Stability; Half-Life; Hydrogen-Ion Concentration; Kinetics; Ligases; Malonyl Coenzyme A; Multienzyme Complexes; NADP; Oxidoreductases; Patulin; Penicillium; Peptide Hydrolases; Phenylmethylsulfonyl Fluoride; Protein Conformation; Sulfhydryl Compounds | 1988 |
Active site organization of bacterial type I fatty acid synthetase.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Acetyl Coenzyme A; Binding Sites; Binding, Competitive; Brevibacterium; Chemical Phenomena; Chemistry; Dithionitrobenzoic Acid; Electrophoresis, Polyacrylamide Gel; Fatty Acid Synthases; Fluorometry; Iodoacetamide; Malonyl Coenzyme A; Palmitoyl Coenzyme A; Pancreatic Elastase; Peptide Fragments; Protein Binding; Transferases; Trypsin | 1987 |
Consequences of reduced intracellular coenzyme A content in Escherichia coli.
Topics: Acetyl Coenzyme A; Alanine; Citric Acid Cycle; Coenzyme A; Escherichia coli; Glutathione; Malonyl Coenzyme A; Mutation; Phospholipids | 1986 |
Different sites of inhibition of carnitine palmitoyltransferase by malonyl-CoA, and by acetyl-CoA and CoA, in human skeletal muscle.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Acyltransferases; Binding Sites; Carnitine O-Palmitoyltransferase; Coenzyme A; Humans; In Vitro Techniques; Malonyl Coenzyme A; Muscles; Octoxynol; Polyethylene Glycols | 1987 |
A biochemical basis for depressed ketogenesis in sepsis.
Topics: Acetyl Coenzyme A; Animals; Carnitine O-Acetyltransferase; Fatty Acids; Infections; Ketone Bodies; Liver; Male; Malonyl Coenzyme A; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1986 |
Thiol/disulfide redox equilibrium and kinetic behavior of chicken liver fatty acid synthase.
Topics: Acetyl Coenzyme A; Animals; Chickens; Disulfides; Dithionitrobenzoic Acid; Electrophoresis, Polyacrylamide Gel; Fatty Acid Synthases; Glutathione; Glutathione Disulfide; Hydrogen-Ion Concentration; Kinetics; Liver; Malonyl Coenzyme A; Mathematics; Oxidation-Reduction; Sulfhydryl Compounds | 1986 |
A novel procedure for the preparation and characterization of catalytically active fatty acid synthetase immobilized on sepharose beads.
Topics: Acetyl Coenzyme A; Enzymes, Immobilized; Fatty Acid Synthases; Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Malonyl Coenzyme A; Methods; Sepharose | 1987 |
Amino acid sequence around the active-site serine residue in the acyltransferase domain of goat mammary fatty acid synthetase.
Topics: Acetyl Coenzyme A; Acyltransferases; Amino Acid Sequence; Animals; Binding Sites; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Fatty Acid Synthases; Female; Goats; Malonyl Coenzyme A; Mammary Glands, Animal; Peptide Fragments; Serine | 1985 |
Fatty acid biosynthesis in the peripheral nervous system of normal and Trembler mice.
Topics: Acetyl Coenzyme A; Animals; Chromatography, Gas; Chromatography, Thin Layer; Fatty Acid Synthases; Fatty Acids; Malonyl Coenzyme A; Mice; Mice, Neurologic Mutants; NADP; Nerve Tissue Proteins; Oxidation-Reduction; Peripheral Nerves; Subcellular Fractions | 1986 |
Malonyl-CoA: acetyl-CoA cycling. A new micromethod for determination of acyl-CoAs with malonate decarboxylase.
Topics: Acetate Kinase; Acetyl Coenzyme A; Acyl Coenzyme A; Carboxy-Lyases; Hot Temperature; Hydrogen-Ion Concentration; Malonyl Coenzyme A; Microchemistry; Pseudomonas | 1985 |
Distribution of reaction intermediates on chicken liver fatty acid synthase.
Topics: Acetyl Coenzyme A; Animals; Chickens; Chromatography, High Pressure Liquid; Fatty Acid Synthases; Liver; Malonyl Coenzyme A; Models, Chemical; NADP; Trypsin | 1985 |
Evidence that the medium-chain acyltransferase of lactating-goat mammary-gland fatty acid synthetase is identical with the acetyl/malonyltransferase.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Acyltransferases; Amino Acid Sequence; Animals; Binding Sites; Fatty Acid Synthases; Female; Formates; Goats; Lactation; Malonyl Coenzyme A; Mammary Glands, Animal; Pregnancy | 1985 |
Inhibition of lipid synthesis by beta beta'-tetramethyl-substituted, C14-C22, alpha, omega-dicarboxylic acids in cultured rat hepatocytes.
Topics: Acetyl Coenzyme A; Animals; Biological Transport; Cells, Cultured; Cholesterol; Citrates; Citric Acid; Dicarboxylic Acids; Dose-Response Relationship, Drug; Glucose; Lipids; Liver; Malonyl Coenzyme A; Methylation; Mitochondria, Liver; Palmitic Acid; Palmitic Acids; Rats; Time Factors | 1985 |
Mechanism of activation of bovine kidney pyruvate dehydrogenase a kinase by malonyl-CoA and enzyme-catalyzed decarboxylation of malonyl-CoA.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Acylation; Animals; Catalysis; Cattle; Decarboxylation; Enzyme Activation; Formates; Ketoglutarate Dehydrogenase Complex; Kidney; Kinetics; Malonyl Coenzyme A; Protein Kinases; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvate Dehydrogenase Complex | 1985 |
Assay of fatty acid synthetase by mass fragmentography using [13C]malonyl-CoA.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Carbon Isotopes; Chemical Phenomena; Chemistry; Decarboxylation; Fatty Acid Synthases; Gas Chromatography-Mass Spectrometry; Guinea Pigs; Malonyl Coenzyme A; Rats; Substrate Specificity; Temperature | 1985 |
Modification of mammalian fatty acid synthetase activity by NADP.
Topics: Acetyl Coenzyme A; Animals; Fatty Acid Synthases; Kinetics; Liver; Malonyl Coenzyme A; NADP; Rats | 1985 |
Effects of DL-2-bromopalmitoyl-CoA and bromoacetyl-CoA in rat liver and heart mitochondria. Inhibition of carnitine palmitoyltransferase and displacement of [14C]malonyl-CoA from mitochondrial binding sites.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Acyltransferases; Animals; Binding Sites; Carnitine Acyltransferases; Carnitine O-Palmitoyltransferase; Coenzyme A; Kinetics; Malonyl Coenzyme A; Mitochondria; Mitochondria, Heart; Mitochondria, Liver; Palmitoyl Coenzyme A; Rats | 1985 |
Stoichiometry of substrate binding to rat liver fatty acid synthetase.
Topics: Acetates; Acetic Acid; Acetyl Coenzyme A; Animals; Binding Sites; Cysteamine; Cysteine; Fatty Acid Synthases; Iodoacetamide; Liver; Malonates; Malonyl Coenzyme A; Pantetheine; Rats | 1985 |
Aspects of lipid metabolism in the foetal, neonatal and adult monogastric mammal.
Topics: Acetate-CoA Ligase; Acetyl Coenzyme A; Acyl Coenzyme A; Adipose Tissue; Aging; Animals; Animals, Newborn; Fatty Acids; Female; Fetus; Lipid Metabolism; Liver; Malonyl Coenzyme A; Pregnancy; Species Specificity | 1980 |
[Activities of 3-hydroxy-3-methylglutaryl-CoA reductase and acetyl-CoA carboxylase and rate of biosynthesis of mevalonic acid, squalene, sterols and fatty acids from [1-14C]acetyl-CoA and [2-14C]malonyl-CoA in rat liver: changes induced by daily rhythm].
Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Animals; Carbon Radioisotopes; Circadian Rhythm; Fatty Acids; Hydroxymethylglutaryl CoA Reductases; Kinetics; Ligases; Liver; Male; Malonyl Coenzyme A; Mevalonic Acid; Radioisotope Dilution Technique; Rats; Squalene; Sterols | 1981 |
[Activities of 3-hydroxyl-3-methylglutaryl-CoA reductase and acetyl-CoA carboxylase and the rate of mevalonic acid, squalene, sterol and fatty acid biosynthesis from [1-14C]acetyl-CoA and [2-14C]malonyl-CoA in rat liver: effects of Triton WR 1339, starvat
Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Animals; Fatty Acids; Humans; Hydroxymethylglutaryl CoA Reductases; Kinetics; Ligases; Liver; Malonyl Coenzyme A; Mevalonic Acid; Polyethylene Glycols; Rats; Squalene; Starvation; Sterols | 1981 |
Fatty acid synthesis in mitochondria of Euglena gracilis.
Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Acyl-CoA Dehydrogenases; Adenosine Triphosphate; Chromatography, DEAE-Cellulose; Cytosol; Euglena gracilis; Fatty Acids; Kinetics; Malonyl Coenzyme A; Microsomes; Mitochondria; NAD; NADP; Substrate Specificity | 1984 |
Rat hepatic microsomal acetoacetyl-CoA reductase. A beta-ketoacyl-CoA reductase distinct from the long chain beta-ketoacyl-CoA reductase component of the microsomal fatty acid chain elongation system.
Topics: Acetoacetates; Acetyl Coenzyme A; Acyl Coenzyme A; Alcohol Oxidoreductases; Animals; Dietary Carbohydrates; Fatty Acid Synthases; Kinetics; Male; Malonyl Coenzyme A; Microsomes, Liver; NAD; Rats; Rats, Inbred Strains | 1984 |
Metabolism of malonic semialdehyde in man.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Alanine; Carbon Dioxide; Carboxy-Lyases; Cell Line; Fibroblasts; Humans; Liver; Malonates; Malondialdehyde; Malonyl Coenzyme A; Mitochondria; Oxidation-Reduction | 1983 |
Malonate, malonyl-coenzyme A, and acetyl-coenzyme A in developing rat brain.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Aging; Animals; Bacterial Proteins; Brain; Carboxy-Lyases; Coenzyme A Ligases; Female; Gestational Age; Malonates; Malonyl Coenzyme A; Pregnancy; Pseudomonas fluorescens; Rats; Rats, Inbred Strains | 1984 |
Kinetic properties of fatty acid synthetase of Neurospora crassa.
Topics: Acetyl Coenzyme A; Citrates; Fatty Acid Synthases; Hydrogen-Ion Concentration; Kinetics; Malonyl Coenzyme A; Manganese; Neurospora; Neurospora crassa; Palmitoyl Coenzyme A | 1980 |
The multifunctional polypeptide chains of rabbit-mammary fatty-acid synthase. Stoichiometry of active sites and active-site mapping using limited proteolysis.
Topics: Acetyl Coenzyme A; Animals; Binding Sites; Electrophoresis, Polyacrylamide Gel; Fatty Acid Synthases; Female; Malonyl Coenzyme A; Mammary Glands, Animal; Pancreatic Elastase; Pantetheine; Peptide Fragments; Rabbits; Sulfhydryl Compounds | 1983 |
Inhibition by acetyl-CoA of hepatic carnitine acyltransferase and fatty acid oxidation.
Topics: Acetyl Coenzyme A; Acyltransferases; Animals; Carnitine O-Palmitoyltransferase; Depression, Chemical; Fatty Acids; Female; In Vitro Techniques; Ketone Bodies; Liver; Male; Malonyl Coenzyme A; Mitochondria, Liver; Oxidation-Reduction; Pregnancy; Rats; Rats, Inbred Strains; Starvation | 1983 |
[Biosynthesis of mevalonic acid, sterols and bile acids from acetyl-CoA and malonyl-CoA in the human liver].
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Bile Acids and Salts; Carbon Radioisotopes; Humans; Kinetics; Liver; Malonyl Coenzyme A; Mevalonic Acid; Sterols | 1983 |
Transient kinetic studies of fatty acid synthetase. A kinetic self-editing mechanism for the loading of acetyl and malonyl residues and the role of coenzyme A.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Chickens; Fatty Acid Synthases; Kinetics; Male; Malonyl Coenzyme A; Mathematics; NADP; Oxidation-Reduction | 1984 |
Determination of malonyl-coenzyme A in rat heart, kidney, and liver: a comparison between acetyl-coenzyme A and butyryl-coenzyme A as fatty acid synthase primers in the assay procedure.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Fatty Acid Synthases; Kidney; Liver; Male; Malonyl Coenzyme A; Myocardium; Rats; Rats, Inbred Strains | 1984 |
Kinetic studies of the fatty acid synthetase multienzyme complex from Euglena gracilis variety bacillaris.
Topics: Acetyl Coenzyme A; Euglena gracilis; Fatty Acid Synthases; Kinetics; Malonyl Coenzyme A; NAD; NADP; Substrate Specificity | 1981 |
Inactivation of 3-oxoacyl synthetase activity of pigeon liver fatty acid synthetase by S-(4-bromo-2,3-dioxobutyl)-coenzyme A.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Acetyl Coenzyme A; Acetyltransferases; Acyl-Carrier Protein S-Acetyltransferase; Acyltransferases; Amino Acids; Animals; Coenzyme A; Columbidae; Cysteine; Enzyme Activation; Fatty Acid Synthases; Iodoacetamide; Kinetics; Liver; Malonyl Coenzyme A; Pantetheine; Spectrophotometry | 1983 |
Propionyl-Coa induced synthesis of even-chain-length fatty acids by fatty acid synthetase from Brevibacterium ammoniagenes.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Brevibacterium; Chemical Phenomena; Chemistry; Deuterium; Fatty Acid Synthases; Fatty Acids; Malonyl Coenzyme A; Oleic Acids; Stearic Acids; Substrate Specificity | 1982 |
Biosynthesis of platelet-activating factor (PAF)acether). III. Formation of PAF-acether from synthetic substrates by stimulated murine macrophages.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Ascitic Fluid; Lysophosphatidylcholines; Macrophage Activation; Macrophages; Malonyl Coenzyme A; Mice; Palmitoyl Coenzyme A; Platelet Activating Factor; Rabbits; Rats; Rats, Inbred Strains; Zymosan | 1982 |
[Biosynthesis of cholic and chenodeoxycholic acids from [1-14C]acetyl-CoA and [2-14C]malonyl-CoA in a reconstituted system from the rat liver].
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Carbon Radioisotopes; Chenodeoxycholic Acid; Cholesterol, Dietary; Cholic Acids; Kinetics; Liver; Male; Malonyl Coenzyme A; Rats | 1981 |
Irreversible inactivation of chicken liver fatty acid synthetase by its substrates acetyl and malonyl CoA. Effect of temperature and NADP n fatty acid and triacetic acid lactone synthesis.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Chickens; Fatty Acid Synthases; Fatty Acids; Liver; Malonyl Coenzyme A; NADP; Pyrans; Pyrones; Temperature | 1981 |
Inactivation of chicken liver fatty acid synthetase by malonyl coenzyme A. Effects of acetyl coenzyme A and nicotinamide adenine dinucleotide phosphate.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Chickens; Circular Dichroism; Dithiothreitol; Fatty Acid Synthases; Kinetics; Liver; Malonyl Coenzyme A; NAD; NADP; Oxidation-Reduction | 1981 |
Coenzyme A is required for rat liver fatty acid synthetase activity.
Topics: Acetyl Coenzyme A; Adenosine Diphosphate; Adenosine Triphosphate; Animals; ATP Citrate (pro-S)-Lyase; Citrates; Coenzyme A; Fatty Acid Synthases; Kinetics; Liver; Malonyl Coenzyme A; Rats | 1980 |
Primer specificity of mammalian mammary gland fatty acid synthetases.
Topics: Acetyl Coenzyme A; Animals; Cattle; Fatty Acid Synthases; Female; Goats; In Vitro Techniques; Malonyl Coenzyme A; Mammary Glands, Animal; Rabbits; Rats; Species Specificity; Substrate Specificity | 1980 |
Substrate control of termination of fatty acid biosynthesis by fatty acid synthetase from Brevibacterium ammoniagenes.
Topics: Acetyl Coenzyme A; Brevibacterium; Fatty Acid Synthases; Fatty Acids; Kinetics; Malonyl Coenzyme A; Oleic Acids | 1980 |
Biochemical properties of cytochrome b5-dependent microsomal fatty acid elongation and identification of products.
Topics: Acetyl Coenzyme A; Animals; Cytochromes; Cytochromes b5; Fatty Acids; Hydrogen-Ion Concentration; Kinetics; Male; Malonyl Coenzyme A; Microsomes, Liver; NAD; NADP; Oxidation-Reduction; Rats | 1980 |
Dissociation of dimeric 6-hydroxymellein synthase, a polyketide biosynthetic enzyme in carrot cell extracts, with loss of keto-reducing activity.
Topics: Acetyl Coenzyme A; Acyltransferases; Binding Sites; Chromatography, High Pressure Liquid; Daucus carota; Kinetics; Ligases; Macromolecular Substances; Malonyl Coenzyme A; Models, Structural; Multienzyme Complexes; Oxidation-Reduction; Oxidoreductases; Substrate Specificity | 1995 |
Cytokines inhibit fatty acid oxidation in isolated rat hepatocytes: synergy among TNF, IL-6, and IL-1.
Topics: Acetyl Coenzyme A; Alanine; Animals; Cells, Cultured; Citric Acid Cycle; Depression, Chemical; Drug Synergism; Energy Metabolism; Fatty Acids; Interleukin-1; Interleukin-6; Ketone Bodies; Liver; Malonyl Coenzyme A; Models, Biological; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 1994 |
Regulation of malonyl-CoA metabolism by acyl-acyl carrier protein and beta-ketoacyl-acyl carrier protein synthases in Escherichia coli.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Acetyl Coenzyme A; Acyl Carrier Protein; Escherichia coli; Fatty Acids; Malonyl Coenzyme A; Phospholipids | 1995 |
Acetyl-CoA carboxylase involvement in the rapid maturation of fatty acid oxidation in the newborn rabbit heart.
Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Age Factors; Animals; Animals, Newborn; Carnitine O-Palmitoyltransferase; Citrates; Dose-Response Relationship, Drug; Fatty Acids; Glucagon; Heart; Insulin; Malonyl Coenzyme A; Mitochondria, Heart; Myocardium; Oxidation-Reduction; Palmitates; Perfusion; Rabbits | 1994 |
Acetoacyl-acyl carrier protein synthase from avocado: its purification, characterisation and clear resolution from acetyl CoA:ACP transacylase.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Acetyl Coenzyme A; Acetyltransferases; Acyl-Carrier Protein S-Acetyltransferase; Buffers; Cerulenin; Fruit; Hydrogen-Ion Concentration; Kinetics; Malonyl Coenzyme A; Molecular Weight; Thiophenes | 1994 |
Enzymatic synthesis of a bacterial polyketide from acetyl and malonyl coenzyme A.
Topics: Acetyl Coenzyme A; Amino Acid Sequence; Anthracenes; Antibody Specificity; Fatty Acid Synthases; Malonyl Coenzyme A; Molecular Sequence Data; Multienzyme Complexes; Streptomyces; Substrate Specificity | 1993 |
Polyketide biosynthesis: molecular recognition or genetic programming?
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Anthraquinones; Anti-Bacterial Agents; Cell-Free System; Erythromycin; Malonyl Coenzyme A; Multienzyme Complexes; Naphthacenes; Streptomyces | 1994 |
Stereospecific acyl transfers on the erythromycin-producing polyketide synthase.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Erythromycin; Malonyl Coenzyme A; Molecular Conformation; Multienzyme Complexes; Racemases and Epimerases; Saccharopolyspora; Stereoisomerism; Substrate Specificity | 1994 |
Coenzyme A biosynthesis in plants: partial purification and characterization of pantothenate kinase from spinach.
Topics: Acetyl Coenzyme A; Acyl Carrier Protein; Adenosine Diphosphate; Amino Acids; Brassica; Cell Compartmentation; Chloroplasts; Coenzyme A; Dose-Response Relationship, Drug; Isoenzymes; Malonyl Coenzyme A; Phosphoric Monoester Hydrolases; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Plants, Edible; Seeds; Subcellular Fractions | 1993 |
Transacylase-like structure and its role in substrate channeling of 6-hydroxymellein synthase, a multifunctional polyketide biosynthetic enzyme in carrot cell extracts.
Topics: Acetyl Coenzyme A; Acyl Carrier Protein; Acyltransferases; Binding Sites; Cysteine; Daucus carota; Ligases; Malonyl Coenzyme A; Molecular Structure; Multienzyme Complexes; Oxidoreductases; Substrate Specificity; Sulfhydryl Compounds; Sulfhydryl Reagents; Sulfones | 1996 |
Propionyl L-carnitine improvement of hypertrophied rat heart function is associated with an increase in cardiac efficiency.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Adenosine Triphosphate; Animals; Cardiomegaly; Cardiotonic Agents; Carnitine; Heart; In Vitro Techniques; Male; Malonyl Coenzyme A; Myocardium; Rats; Rats, Inbred WKY | 1995 |
Effect of NADPH-associated keto-reducing domain on substrate entry into 6-hydroxymellein synthase, a multifunctional polyketide synthetic enzyme involved in phytoalexin biosynthesis in carrot.
Topics: Acetyl Coenzyme A; Acyltransferases; Daucus carota; Kinetics; Ligases; Malonyl Coenzyme A; Models, Chemical; Multienzyme Complexes; NADP; Oxidoreductases; Phytoalexins; Plant Extracts; Pyrones; Sesquiterpenes; Terpenes | 1996 |
Structural similarities between 6-methylsalicylic acid synthase from Penicillium patulum and vertebrate type I fatty acid synthase: evidence from thiol modification studies.
Topics: Acetone; Acetyl Coenzyme A; Acyltransferases; Amino Acid Sequence; Animals; Antifungal Agents; Binding Sites; Centrifugation, Density Gradient; Cerulenin; Cross-Linking Reagents; Dithionitrobenzoic Acid; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Fatty Acid Synthases; Iodoacetamide; Ligases; Malonyl Coenzyme A; Molecular Sequence Data; Molecular Weight; Multienzyme Complexes; Oxidoreductases; Penicillium; Protein Conformation; Serine Endopeptidases; Sulfhydryl Reagents | 1996 |
Expression in Escherichia coli and refolding of the malonyl-/acetyltransferase domain of the multifunctional animal fatty acid synthase.
Topics: Acetyl Coenzyme A; Acetyl-CoA C-Acetyltransferase; Acyl-Carrier Protein S-Malonyltransferase; Acyltransferases; Amino Acid Sequence; Animals; Base Sequence; Chickens; Diethyl Pyrocarbonate; Escherichia coli; Escherichia coli Proteins; Fatty Acid Synthase, Type II; Fatty Acid Synthases; Humans; Kinetics; Malonyl Coenzyme A; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Rats; Sequence Alignment; Structure-Activity Relationship | 1996 |
Changes in the size and composition of intracellular pools of nonesterified coenzyme A and coenzyme A thioesters in aerobic and facultatively anaerobic bacteria.
Topics: Acetyl Coenzyme A; Anaerobiosis; Bacteria, Aerobic; Cerulenin; Coenzyme A; Energy Metabolism; Enzyme Inhibitors; Esters; Fatty Acid Synthases; Fatty Acids; Feedback; Gene Expression Regulation, Enzymologic; Glucose; Gram-Negative Facultatively Anaerobic Rods; Malonyl Coenzyme A; Potassium Cyanide; Species Specificity; Sulfhydryl Compounds | 1997 |
Alteration of the substrate specificity of the malonyl-CoA/acetyl-CoA:acyl carrier protein S-acyltransferase domain of the multifunctional fatty acid synthase by mutation of a single arginine residue.
Topics: Acetyl Coenzyme A; Amino Acid Sequence; Animals; Arginine; Cloning, Molecular; Coenzyme A-Transferases; Conserved Sequence; Escherichia coli; Fatty Acid Synthases; Kinetics; Malonyl Coenzyme A; Mutagenesis, Site-Directed; Point Mutation; Rats; Recombinant Proteins; Substrate Specificity | 1997 |
[Rapid induction of hepatic acetyl-CoA carboxylase activity after estradiol benzoate injection in the quail].
Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Animals; Coturnix; Enzyme Induction; Estradiol; Fatty Acids; Kinetics; Liver; Malonyl Coenzyme A | 1981 |
Stromal concentrations of coenzyme A and its esters are insufficient to account for rates of chloroplast fatty acid synthesis: evidence for substrate channelling within the chloroplast fatty acid synthase.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Cell Extracts; Cell Membrane Permeability; Chloroplasts; Chromatography, High Pressure Liquid; Coenzyme A; Detergents; Fatty Acid Synthases; Fatty Acids; Glutathione; Malonyl Coenzyme A; Octoxynol; Pisum sativum; Spinacia oleracea | 1997 |
Fatty acid synthesis of an eicosapentaenoic acid-producing bacterium: de novo synthesis, chain elongation, and desaturation systems.
Topics: Acetyl Coenzyme A; Acyl Carrier Protein; Cerulenin; Eicosapentaenoic Acid; Enzyme Inhibitors; Fatty Acid Desaturases; Fatty Acids; Gram-Negative Facultatively Anaerobic Rods; Malonyl Coenzyme A; Models, Chemical; NAD; NADP | 1997 |
Inactivation of the polyketide synthase, 6-methylsalicylic acid synthase, by the specific modification of Cys-204 of the beta-ketoacyl synthase by the fungal mycotoxin cerulenin.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Acetyl Coenzyme A; Acyltransferases; Alkylation; Antifungal Agents; Binding, Competitive; Cerulenin; Cyanogen Bromide; Cysteine; Iodoacetamide; Kinetics; Ligases; Malonyl Coenzyme A; Models, Chemical; Multienzyme Complexes; Oxidoreductases; Penicillium; Peptide Mapping; Serine Endopeptidases; Staphylococcus aureus | 1998 |
Inactivation of enoyl-CoA reductase in pigeon liver fatty acid synthetase by pyridoxal 5'-phosphate: evidence for the presence of one lysine residue at the active site.
Topics: Acetyl Coenzyme A; Animals; Binding Sites; Columbidae; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Enzyme Inhibitors; Fatty Acid Synthases; Kinetics; Liver; Lysine; Malonyl Coenzyme A; Oxidoreductases; Pyridoxal Phosphate; Spectrometry, Fluorescence | 1998 |
Changes in size of intracellular pools of coenzyme A and its thioesters in Escherichia coli K-12 cells to various carbon sources and stresses.
Topics: Acetyl Coenzyme A; Carbon; Coenzyme A; Culture Media; Escherichia coli; Glucose; Hydrogen-Ion Concentration; Malonyl Coenzyme A; Osmotic Pressure; Temperature | 1998 |
Regulation of spinach chloroplast acetyl-CoA carboxylase.
Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Acyl Coenzyme A; Chloroplasts; Coenzyme A; Darkness; Dithiothreitol; Enzyme Activation; Hydrogen-Ion Concentration; Light; Malonyl Coenzyme A; Spinacia oleracea; Subcellular Fractions; Thioredoxins | 1998 |
A gene cluster encoding malonyl-CoA decarboxylase (MatA), malonyl-CoA synthetase (MatB) and a putative dicarboxylate carrier protein (MatC) in Rhizobium trifolii--cloning, sequencing, and expression of the enzymes in Escherichia coli.
Topics: Acetyl Coenzyme A; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Carboxy-Lyases; Carrier Proteins; Cloning, Molecular; Coenzyme A Ligases; Dicarboxylic Acid Transporters; DNA Primers; Escherichia coli; Malonates; Malonyl Coenzyme A; Molecular Sequence Data; Multigene Family; Rhizobium; Sequence Deletion | 1998 |
Fatty acid synthase dimers containing catalytically active beta-ketoacyl synthase or malonyl/acetyltransferase domains in only one subunit can support fatty acid synthesis at the acyl carrier protein domains of both subunits.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Acetyl Coenzyme A; Acyl Carrier Protein; Acyltransferases; Catalytic Domain; Dimerization; Fatty Acid Synthases; Fatty Acids; Malonyl Coenzyme A; Mutation | 1998 |
Presence of acetyl coenzyme A (CoA) carboxylase and propionyl-CoA carboxylase in autotrophic Crenarchaeota and indication for operation of a 3-hydroxypropionate cycle in autotrophic carbon fixation.
Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Acyl Coenzyme A; Aerobiosis; Biotin; Carbon Dioxide; Carboxy-Lyases; Chlorobi; Crenarchaeota; Genes, Archaeal; Lactic Acid; Malonyl Coenzyme A; Methylmalonyl-CoA Decarboxylase; Peptides; Sequence Homology; Succinic Acid; Sulfolobaceae | 1999 |
Dissection of malonyl-coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase.
Topics: Acetyl Coenzyme A; Acyltransferases; Amino Acid Sequence; Amino Acid Substitution; Base Sequence; Coenzyme A; Crystallography, X-Ray; Decarboxylation; Enzyme Activation; Flavanones; Flavonoids; Malonyl Coenzyme A; Medicago sativa; Molecular Sequence Data; Multienzyme Complexes; Mutagenesis, Site-Directed; Plant Proteins; Recombinant Proteins; Spectrometry, Fluorescence; Structure-Activity Relationship; Titrimetry | 2000 |
Sensitivity of CPT I to malonyl-CoA in trained and untrained human skeletal muscle.
Topics: Acetyl Coenzyme A; Acetylcarnitine; Adult; Carnitine O-Palmitoyltransferase; Coenzyme A; Female; Humans; Hydrogen-Ion Concentration; Male; Malonyl Coenzyme A; Mitochondria, Muscle; Muscle, Skeletal; Physical Education and Training; Reference Values | 2000 |
Tolerance and specificity of recombinant 6-methylsalicyclic acid synthase.
Topics: Acetyl Coenzyme A; Acyltransferases; Amino Acid Sequence; Base Sequence; Cloning, Molecular; Escherichia coli; Kinetics; Ligases; Malonyl Coenzyme A; Multienzyme Complexes; Mutagenesis, Site-Directed; Oxidoreductases; Penicillium; Recombinant Proteins; Saccharomyces cerevisiae; Substrate Specificity | 1999 |
Purification and characterization of the fatty acid synthase from Bugula neritina.
Topics: Acetyl Coenzyme A; Animals; Bryozoa; Chromatography, Gel; Chromatography, Ion Exchange; Cytosol; Fatty Acid Synthases; Hydrogen-Ion Concentration; Kinetics; Malonyl Coenzyme A; Molecular Weight; NAD; NADP; Substrate Specificity | 2001 |
Regulation of myocardial fatty acid oxidation by substrate supply.
Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Adenylate Kinase; Aminoimidazole Carboxamide; Animals; Fatty Acids; Glycolysis; In Vitro Techniques; Male; Malonyl Coenzyme A; Myocardium; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Ribonucleotides; Substrate Specificity | 2001 |
Enzymes involved in fatty acid and polyketide biosynthesis in Streptomyces glaucescens: role of FabH and FabD and their acyl carrier protein specificity.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Acetic Acid; Acetyl Coenzyme A; Acetyl-CoA C-Acetyltransferase; Acyl Carrier Protein; Amino Acid Sequence; Animals; Carbon Isotopes; Deuterium; Enzyme Activation; Fatty Acids; Malonyl Coenzyme A; Molecular Sequence Data; Multienzyme Complexes; Naphthacenes; Recombinant Proteins; Spodoptera; Streptomyces; Substrate Specificity; Transferases (Other Substituted Phosphate Groups) | 2002 |
Probing the link between citrate and malonyl-CoA in perfused rat hearts.
Topics: Acetyl Coenzyme A; Animals; ATP Citrate (pro-S)-Lyase; Carbon Isotopes; Citrates; Citric Acid; Citric Acid Cycle; Gas Chromatography-Mass Spectrometry; In Vitro Techniques; Male; Malonyl Coenzyme A; Myocardial Contraction; Myocardium; Perfusion; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2002 |
Quantitative analysis of loading and extender acyltransferases of modular polyketide synthases.
Topics: Acetyl Coenzyme A; Acyl Carrier Protein; Acyl Coenzyme A; Acyltransferases; Cysteamine; Genetic Vectors; Histidine; Kinetics; Malonyl Coenzyme A; Multienzyme Complexes; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Protein Subunits; Quantitative Structure-Activity Relationship; Sirolimus; Substrate Specificity | 2003 |
Characterization of acetyl-CoA/propionyl-CoA carboxylase in Metallosphaera sedula. Carboxylating enzyme in the 3-hydroxypropionate cycle for autotrophic carbon fixation.
Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Acyl Coenzyme A; Biotin; Blotting, Southern; Carbon Dioxide; Carbon-Nitrogen Ligases; Carboxy-Lyases; Catalysis; Cloning, Molecular; Escherichia coli; Fatty Acid Desaturases; Hot Temperature; Malonyl Coenzyme A; Methylmalonyl-CoA Decarboxylase; Oxidoreductases; Plasmids; Protein Subunits; Sulfolobaceae | 2003 |
Functional analysis of a beta-ketoacyl-CoA synthase gene, MpFAE2, by gene silencing in the liverwort Marchantia polymorpha L.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Acetyl Coenzyme A; Amino Acid Sequence; Blotting, Northern; Blotting, Southern; Fatty Acids; Gene Silencing; Hepatophyta; Malonyl Coenzyme A; Molecular Sequence Data; Nucleic Acid Conformation; Plants, Genetically Modified; RNA Interference; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity | 2003 |
The stable isotope-based dynamic metabolic profile of butyrate-induced HT29 cell differentiation.
Topics: Acetyl Coenzyme A; Adenocarcinoma; Butyrates; Carbon Isotopes; Cell Differentiation; Cell Division; Colonic Neoplasms; Glucose; Glycolysis; HT29 Cells; Humans; Malonyl Coenzyme A; Oxidation-Reduction; Pancreatic Neoplasms; Pentose Phosphate Pathway | 2003 |
THE FORMATION OF ACETOACETATE FROM ACETYL COENZYME A, MALONYL COENZYME A,AND PYRUVATE BY WASHED MITOCHONDRIA ISOLATED FROM GUINEA PIG LIVER.
Topics: Acetates; Acetoacetates; Acetyl Coenzyme A; Adenosine Triphosphate; Antimetabolites; Bicarbonates; Biotin; Carbon Isotopes; Chromatography; Coenzyme A; Egg White; Guinea Pigs; Lipid Metabolism; Liver; Malonates; Malonyl Coenzyme A; Mitochondria; Pharmacology; Pyruvates; Pyruvic Acid; Research | 1963 |
SYNTHESIS OF MALONYL-COENZYME A FROM ACETYL-COENZYME A AND OXALOSUCCINATE IN MITOCHONDRIA.
Topics: Acetates; Acetyl Coenzyme A; Biotin; Carbon Isotopes; Chromatography; Citric Acid Cycle; Coenzyme A; Keto Acids; Malonates; Malonyl Coenzyme A; Manometry; Mitochondria; Myocardium; Rats; Research; Succinates | 1963 |
Carboxymethylproline synthase (CarB), an unusual carbon-carbon bond-forming enzyme of the crotonase superfamily involved in carbapenem biosynthesis.
Topics: Acetyl Coenzyme A; Amino Acid Sequence; Carbapenems; Carbon; Carbon-Carbon Lyases; Chromatography, Gel; Circular Dichroism; Cloning, Molecular; Dithionitrobenzoic Acid; Electrophoresis, Polyacrylamide Gel; Enoyl-CoA Hydratase; Glutamates; Glutamic Acid; Kinetics; Lactams; Magnetic Resonance Spectroscopy; Malonyl Coenzyme A; Mass Spectrometry; Models, Chemical; Molecular Sequence Data; Pectobacterium; Protein Binding; Recombinant Proteins; Sequence Homology, Amino Acid; Stereoisomerism; Thienamycins | 2004 |
Role of the active site cysteine of DpgA, a bacterial type III polyketide synthase.
Topics: Acetyl Coenzyme A; Alanine; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Carbon Radioisotopes; Catalysis; Coenzyme A Ligases; Cysteine; Decarboxylation; Kinetics; Malonyl Coenzyme A; Molecular Sequence Data; Mutagenesis, Site-Directed; Substrate Specificity | 2004 |
The first plant type III polyketide synthase that catalyzes formation of aromatic heptaketide.
Topics: Acetyl Coenzyme A; Amino Acid Sequence; Catalysis; Escherichia coli; Malonyl Coenzyme A; Molecular Sequence Data; Molecular Structure; Multienzyme Complexes; Mutagenesis, Site-Directed; Phylogeny; Plant Proteins; Rheum; Sequence Alignment | 2004 |
Characterization of fatty acid synthase activity using scintillation proximity.
Topics: Acetyl Coenzyme A; Animals; Fatty Acid Synthases; In Vitro Techniques; Liver; Male; Malonyl Coenzyme A; Palmitic Acid; Rats; Reproducibility of Results; Scintillation Counting; Tritium | 2003 |
Malonyl coenzyme a decarboxylase inhibition protects the ischemic heart by inhibiting fatty acid oxidation and stimulating glucose oxidation.
Topics: Acetyl Coenzyme A; Animals; Carboxy-Lyases; Cardiotonic Agents; Energy Metabolism; Enzyme Inhibitors; Esters; Fatty Acids; Glucose; Glycolysis; Malonyl Coenzyme A; Mitochondria, Heart; Models, Animal; Myocardial Ischemia; Myocardium; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Swine | 2004 |
Glucosinolate biosynthesis: demonstration and characterization of the condensing enzyme of the chain elongation cycle in Eruca sativa.
Topics: 2-Isopropylmalate Synthase; Acetyl Coenzyme A; Brassicaceae; Cations, Divalent; Chloroplasts; Glucosinolates; Hydrolysis; Malate Synthase; Malonyl Coenzyme A; Mass Spectrometry; Methionine; Species Specificity; Substrate Specificity; Tritium | 2004 |
Regulation of malonyl-CoA concentration and turnover in the normal heart.
Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Animals; Biochemical Phenomena; Biochemistry; Carboxy-Lyases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart; Kinetics; Malonyl Coenzyme A; Myocardium; Perfusion; Rats; Rats, Sprague-Dawley; Swine; Time Factors | 2004 |
In vitro modeling of fatty acid synthesis under conditions simulating the zonation of lipogenic [13C]acetyl-CoA enrichment in the liver.
Topics: Acetyl Coenzyme A; Animals; Fatty Acids; Glucose; Lipid Metabolism; Liver; Liver Extracts; Malonyl Coenzyme A; Models, Theoretical; Rats; Subcellular Fractions; Time Factors | 2004 |
Malonyl-CoA and carnitine in regulation of fat oxidation in human skeletal muscle during exercise.
Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Acetylcarnitine; Adenylate Kinase; Adult; Carnitine; Dietary Carbohydrates; Exercise; Fatty Acids; Glucose; Glycogen; Heart Rate; Humans; Insulin; Male; Malonyl Coenzyme A; Muscle, Skeletal; Oxidation-Reduction; Pyruvate Dehydrogenase Complex | 2005 |
[Lipogenesis: does it have a relevance in the obesity research?].
Topics: Acetyl Coenzyme A; Dietary Carbohydrates; Humans; Hyperinsulinism; Lipid Metabolism; Lipids; Malonyl Coenzyme A; Obesity; Research | 2004 |
Connection of propionyl-CoA metabolism to polyketide biosynthesis in Aspergillus nidulans.
Topics: Acetate-CoA Ligase; Acetyl Coenzyme A; Acyl Coenzyme A; Amino Acid Sequence; Aspergillus nidulans; Citrate (si)-Synthase; Gene Expression Regulation, Fungal; Malonates; Malonyl Coenzyme A; Methylmalonyl-CoA Decarboxylase; Molecular Sequence Data; Propionates; Sequence Homology, Amino Acid; Sterigmatocystin | 2004 |
Peroxisomal and mitochondrial oxidation of fatty acids in the heart, assessed from the 13C labeling of malonyl-CoA and the acetyl moiety of citrate.
Topics: Acetyl Coenzyme A; Acetylation; Acetylcarnitine; Animals; Carbon Isotopes; Citrates; Fatty Acids, Nonesterified; Kinetics; Male; Malonyl Coenzyme A; Mitochondria, Heart; Myocardium; Oxidation-Reduction; Peroxisomes; Rats; Rats, Sprague-Dawley | 2005 |
Characterization of the inactivation of rat fatty acid synthase by C75: inhibition of partial reactions and protection by substrates.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase; 4-Butyrolactone; Acetyl Coenzyme A; Alcohol Oxidoreductases; Animals; Binding, Competitive; Dithiothreitol; Enzyme Activation; Fatty Acid Synthases; Kinetics; Liver; Malonyl Coenzyme A; NADP; Rats; Substrate Specificity; Temperature | 2005 |
Probing peroxisomal beta-oxidation and the labelling of acetyl-CoA proxies with [1-(13C)]octanoate and [3-(13C)]octanoate in the perfused rat liver.
Topics: Acetates; Acetyl Coenzyme A; Acetylcarnitine; Animals; Caprylates; Carbon Isotopes; Citric Acid; Isotope Labeling; Ketone Bodies; Liver; Male; Malonyl Coenzyme A; Mitochondria, Liver; Oxidation-Reduction; Perfusion; Peroxisomes; Rats; Rats, Sprague-Dawley | 2005 |
Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice.
Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Dietary Fats; Diglycerides; Fasting; Fatty Liver; Glucose Tolerance Test; Glycerol-3-Phosphate O-Acyltransferase; Insulin Resistance; Liver; Lysophospholipids; Male; Malonyl Coenzyme A; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Multienzyme Complexes; Phenotype; Protein Serine-Threonine Kinases; Triglycerides | 2005 |
Competition between acetate and oleate for the formation of malonyl-CoA and mitochondrial acetyl-CoA in the perfused rat heart.
Topics: Acetates; Acetyl Coenzyme A; Animals; Fatty Acids; In Vitro Techniques; Male; Malonyl Coenzyme A; Mitochondria, Heart; Models, Cardiovascular; Myocardium; Oleic Acid; Oxidation-Reduction; Perfusion; Propionates; Rats; Rats, Sprague-Dawley | 2006 |
Determination of acetyl-CoA and malonyl-CoA in germinating rice seeds using the LC-MS/MS technique.
Topics: Acetyl Coenzyme A; Chromatography, Liquid; Malonyl Coenzyme A; Mass Spectrometry; Oryza; Seedlings; Seeds; Time Factors | 2006 |
Malonyl CoA control of fatty acid oxidation in the newborn heart in response to increased fatty acid supply.
Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Animals, Newborn; Carboxy-Lyases; Carnitine O-Palmitoyltransferase; Citric Acid Cycle; Dose-Response Relationship, Drug; Glucose; In Vitro Techniques; Malonyl Coenzyme A; Multienzyme Complexes; Myocardium; Oxidation-Reduction; Palmitic Acid; Protein Serine-Threonine Kinases; Rabbits | 2006 |
Goat acetyl-coenzyme A carboxylase alpha: molecular characterization, polymorphism, and association with milk traits.
Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Animals; Cattle; Cell Count; DNA, Complementary; Fats; Gene Frequency; Genotype; Goats; Malonyl Coenzyme A; Milk; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Sequence Analysis, DNA; Sequence Homology; Sheep; Species Specificity | 2007 |
Simultaneous quantification of malonyl-CoA and several other short-chain acyl-CoAs in animal tissues by ion-pairing reversed-phase HPLC/MS.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Chromatography, High Pressure Liquid; Liver; Malonyl Coenzyme A; Mice; Molecular Structure; Muscle, Skeletal; Myocardium; Rats; Rats, Sprague-Dawley; Reproducibility of Results | 2007 |
GNAT-like strategy for polyketide chain initiation.
Topics: Acetyl Coenzyme A; Acetyltransferases; Acyl Carrier Protein; Amino Acid Sequence; Carboxy-Lyases; Crystallography, X-Ray; Cyanobacteria; Cyclopropanes; Decarboxylation; Malonyl Coenzyme A; Models, Molecular; Molecular Sequence Data; Polyketide Synthases; Protein Conformation; Protein Structure, Tertiary; Thiazoles | 2007 |
Differences in concentrations of acetyl-CoA and malonyl-CoA in shoots and roots of Zea mays.
Topics: Acetyl Coenzyme A; Darkness; Light; Malonyl Coenzyme A; Plant Roots; Plant Shoots; Zea mays | 2008 |
Production of the polyketide 6-MSA in yeast engineered for increased malonyl-CoA supply.
Topics: Acetyl Coenzyme A; Acetyltransferases; Acyltransferases; Aspergillus nidulans; Ligases; Macrolides; Malonyl Coenzyme A; Multienzyme Complexes; Oxidoreductases; Penicillium; Peptide Elongation Factor 1; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salicylates | 2008 |
Abrogation of hepatic ATP-citrate lyase protects against fatty liver and ameliorates hyperglycemia in leptin receptor-deficient mice.
Topics: Acetyl Coenzyme A; Animals; ATP Citrate (pro-S)-Lyase; Fatty Acids, Nonesterified; Fatty Liver; Glucose; Homeostasis; Hyperglycemia; Insulin Resistance; Lipid Metabolism; Lipogenesis; Liver; Male; Malonyl Coenzyme A; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Leptin; RNA Interference | 2009 |
An alternative to the glyoxylate shunt.
Topics: Acetates; Acetyl Coenzyme A; Acyl Coenzyme A; Bacteria; Bicarbonates; Carbon Dioxide; Glyoxylates; Malonyl Coenzyme A; Metabolic Networks and Pathways | 2009 |
Pantothenate kinase from the thermoacidophilic archaeon Picrophilus torridus.
Topics: Acetyl Coenzyme A; Amino Acid Sequence; Coenzyme A; Electrophoresis, Polyacrylamide Gel; Genome, Archaeal; Kinetics; Malonyl Coenzyme A; Molecular Sequence Data; Phosphotransferases (Alcohol Group Acceptor); Phylogeny; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Substrate Specificity; Thermoplasmales | 2010 |
Enzymatic total synthesis of rabelomycin, an angucycline group antibiotic.
Topics: Acetyl Coenzyme A; Anthraquinones; Anti-Bacterial Agents; Catalysis; Malonyl Coenzyme A; Molecular Structure; Polyketide Synthases; Streptomyces | 2010 |
Coenzyme A and its thioester pools in fasted and fed rat tissues.
Topics: Acetyl Coenzyme A; Animals; Brain; Coenzyme A; Eating; Fasting; Female; Male; Malonyl Coenzyme A; Rats; Rats, Wistar; Tissue Distribution | 2010 |
Development and validation of a highly sensitive LC-MS/MS method for simultaneous quantitation of acetyl-CoA and malonyl-CoA in animal tissues.
Topics: Acetonitriles; Acetyl Coenzyme A; Animals; Calibration; Chromatography, Liquid; Drug Stability; Formates; High-Throughput Screening Assays; Linear Models; Liver; Male; Malonyl Coenzyme A; Muscle, Skeletal; Myocardium; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry | 2011 |
Cloning, expression, and enzymatic activity of Acinetobacter baumannii and Klebsiella pneumoniae acetyl-coenzyme A carboxylases.
Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Acinetobacter baumannii; Adenosine Triphosphatases; Biocatalysis; Carbon-Nitrogen Ligases; Cloning, Molecular; Fluorometry; Kinetics; Klebsiella pneumoniae; Malonyl Coenzyme A; Protein Subunits; Recombinant Proteins | 2011 |
Second window of preconditioning normalizes palmitate use for oxidation and improves function during low-flow ischaemia.
Topics: Acetyl Coenzyme A; Animals; Coronary Circulation; Coronary Stenosis; Disease Models, Animal; Energy Metabolism; Glycolysis; Hemodynamics; Ischemic Preconditioning, Myocardial; Malonyl Coenzyme A; Myocardial Contraction; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardial Stunning; Myocardium; Oxidation-Reduction; Palmitic Acid; Recovery of Function; Sus scrofa; Time Factors; Ventricular Function, Left | 2011 |
Polyketide proofreading by an acyltransferase-like enzyme.
Topics: Acetyl Coenzyme A; Acyltransferases; Bacillus; Malonyl Coenzyme A; Phylogeny; Polyenes; Polyketides; Pyrans | 2012 |
Effect of diet composition on coenzyme A and its thioester pools in various rat tissues.
Topics: Acetyl Coenzyme A; Animals; Body Weight; Coenzyme A; Diet, High-Fat; Energy Intake; Hypothalamus; Lipid Metabolism; Liver; Male; Malonyl Coenzyme A; Muscle, Skeletal; Obesity; Organ Specificity; Rats; Rats, Wistar; Tissue Distribution; Weight Gain | 2012 |
A type III polyketide synthase from Rhizobium etli condenses malonyl CoAs to a heptaketide pyrone with unusually high catalytic efficiency.
Topics: Acetyl Coenzyme A; Amino Acid Sequence; Binding Sites; Catalysis; Malonyl Coenzyme A; Molecular Dynamics Simulation; Polyketide Synthases; Protein Binding; Protein Structure, Secondary; Pyrones; Rhizobium etli; Sequence Alignment; Substrate Specificity | 2012 |
Pressure-overload-induced heart failure induces a selective reduction in glucose oxidation at physiological afterload.
Topics: Acetyl Coenzyme A; Animals; Echocardiography; Glucose; Glucose Transporter Type 4; Heart Failure; Hypertension; Hypertrophy, Left Ventricular; Lactic Acid; Male; Malonyl Coenzyme A; Mice; Mice, Inbred C57BL; Myocardial Reperfusion Injury; Systole | 2013 |
Metabolic engineering for enhanced fatty acids synthesis in Saccharomyces cerevisiae.
Topics: Acetyl Coenzyme A; Biofuels; Citric Acid Cycle; Fatty Acids, Unsaturated; Isocitrate Dehydrogenase; Malonyl Coenzyme A; Metabolic Engineering; Multienzyme Complexes; Oxo-Acid-Lyases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2013 |
The yeast AMPK homolog SNF1 regulates acetyl coenzyme A homeostasis and histone acetylation.
Topics: Acetyl Coenzyme A; Acetylation; Acetyltransferases; Chromatin; Coenzyme A Ligases; DNA, Fungal; DNA, Intergenic; Epigenetic Repression; Gene Expression Regulation, Fungal; Gene Knockout Techniques; Histone Acetyltransferases; Histone Deacetylases; Histones; Homeostasis; Malonyl Coenzyme A; Promoter Regions, Genetic; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Saccharomyces cerevisiae; Stress, Physiological | 2013 |
Fatty acid chain elongation in palmitate-perfused working rat heart: mitochondrial acetyl-CoA is the source of two-carbon units for chain elongation.
Topics: Acetyl Coenzyme A; Animals; Carnitine O-Palmitoyltransferase; Enzyme Inhibitors; Malonyl Coenzyme A; Mitochondria, Heart; Muscle Proteins; Myocardium; Oxidation-Reduction; Palmitic Acid; Palmitoyl Coenzyme A; Perfusion; Rats; Rats, Inbred F344 | 2014 |
Enhanced acetyl-CoA production is associated with increased triglyceride accumulation in the green alga Chlorella desiccata.
Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Amino Acid Sequence; Chlorella; Coenzyme A; Gene Expression Regulation, Plant; Malonyl Coenzyme A; Metabolic Networks and Pathways; Molecular Sequence Data; Nitrogen; Plant Proteins; Plastids; Pyruvate Dehydrogenase (Lipoamide); Reference Standards; RNA, Messenger; Starch; Triglycerides | 2015 |
Phosphorylation of Ser-204 and Tyr-405 in human malonyl-CoA decarboxylase expressed in silkworm Bombyx mori regulates catalytic decarboxylase activity.
Topics: Acetyl Coenzyme A; Amino Acid Sequence; Animals; Baculoviridae; Biotransformation; Bombyx; Carboxy-Lyases; DNA Mutational Analysis; Gene Expression; Genetic Vectors; Humans; Kinetics; Malonyl Coenzyme A; Models, Molecular; Molecular Sequence Data; Phosphorylation; Point Mutation; Protein Conformation; Protein Processing, Post-Translational; Recombinant Proteins | 2015 |
Regulating effect of β-ketoacyl synthase domain of fatty acid synthase on fatty acyl chain length in de novo fatty acid synthesis.
Topics: Acetyl Coenzyme A; Binding Sites; Catalysis; Catalytic Domain; Fatty Acid Synthases; Fatty Acids; Malonyl Coenzyme A; Molecular Dynamics Simulation; NADP; Oxidation-Reduction; Protein Binding; Protein Structure, Tertiary; Structure-Activity Relationship; Substrate Specificity | 2016 |
Decreased hepatic contents of coenzyme A molecular species in mice after subchronic mild social defeat stress.
Topics: Acetyl Coenzyme A; Animals; Body Weight; Coenzyme A; Depression; Disease Models, Animal; Down-Regulation; Hypothalamus; Liver; Male; Malonyl Coenzyme A; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Stress, Psychological; Weight Gain | 2016 |
Overexpression of ACC gene from oleaginous yeast Lipomyces starkeyi enhanced the lipid accumulation in Saccharomyces cerevisiae with increased levels of glycerol 3-phosphate substrates.
Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Amino Acid Sequence; Fatty Acids; Fungal Proteins; Gene Expression Regulation, Fungal; Glycerol-3-Phosphate Dehydrogenase (NAD+); Glycerophosphates; Lipid Metabolism; Lipomyces; Malonyl Coenzyme A; Metabolic Engineering; Phylogeny; Real-Time Polymerase Chain Reaction; Saccharomyces cerevisiae; Sequence Alignment; Transgenes | 2016 |
Identification of the active site of human mitochondrial malonyl-coenzyme a decarboxylase: A combined computational study.
Topics: Acetyl Coenzyme A; Carboxy-Lyases; Catalytic Domain; Cyclopropanes; Humans; Malonyl Coenzyme A; Mitochondria; Molecular Docking Simulation; Molecular Dynamics Simulation; Thermodynamics; Thiazoles | 2016 |
Activation of AMP-activated Protein Kinase by Metformin Induces Protein Acetylation in Prostate and Ovarian Cancer Cells.
Topics: Acetyl Coenzyme A; Acetylation; AMP-Activated Protein Kinases; Female; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Male; Malonyl Coenzyme A; Metformin; Neoplasm Proteins; Ovarian Neoplasms; Prostatic Neoplasms; Protein Processing, Post-Translational | 2016 |
Functional reconstitution of the Mycobacterium tuberculosis long-chain acyl-CoA carboxylase from multiple acyl-CoA subunits.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Bacterial Proteins; Carbon-Carbon Ligases; Cloning, Molecular; Enzyme Assays; Escherichia coli; Gene Expression; Kinetics; Malonyl Coenzyme A; Mycobacterium tuberculosis; Mycolic Acids; Polyketide Synthases; Protein Engineering; Protein Subunits; Recombinant Proteins; Substrate Specificity | 2017 |
Production of 3-hydroxypropionic acid via the malonyl-CoA pathway using recombinant fission yeast strains.
Topics: Acetyl Coenzyme A; Chloroflexus; Cytosol; Heat-Shock Proteins; Kinesins; Lactic Acid; Malonyl Coenzyme A; Oxidoreductases; Promoter Regions, Genetic; Schizosaccharomyces; Schizosaccharomyces pombe Proteins | 2017 |
Structural and Functional Studies of the Daunorubicin Priming Ketosynthase DpsC.
Topics: Acetyl Coenzyme A; Acylation; Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Daunorubicin; Malonyl Coenzyme A; Models, Molecular; Polyketide Synthases; Protein Conformation; Streptomyces | 2018 |
Cytosolic reverse CrAT activity in cardiac tissue: potential importance for fuel selection.
Topics: Acetyl Coenzyme A; Carnitine O-Acetyltransferase; Carnitine O-Palmitoyltransferase; Cytosol; Energy Metabolism; Malonyl Coenzyme A | 2018 |
Metabolic reprogramming enables hepatocarcinoma cells to efficiently adapt and survive to a nutrient-restricted microenvironment.
Topics: Acetyl Coenzyme A; Adaptation, Physiological; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Survival; Citric Acid; Citric Acid Cycle; Fatty Acids; Gene Expression Regulation, Neoplastic; Glucose; Glucose Transporter Type 1; Glycolysis; Hep G2 Cells; Hexokinase; Humans; L-Lactate Dehydrogenase; Lipid Metabolism; Liver Neoplasms; Malonyl Coenzyme A; Mice; Signal Transduction; Survival Analysis; Triglycerides | 2018 |
Overexpression of acetyl-CoA carboxylase in Aspergillus terreus to increase lovastatin production.
Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Aspergillus; Fungal Proteins; Lovastatin; Malonyl Coenzyme A | 2018 |
Modular pathway engineering for resveratrol and piceatannol production in engineered Escherichia coli.
Topics: Acetyl Coenzyme A; Biosynthetic Pathways; Escherichia coli; Escherichia coli Proteins; Malonyl Coenzyme A; Metabolic Engineering; Resveratrol; Stilbenes | 2018 |
Biochemical characterization of the minimal domains of an iterative eukaryotic polyketide synthase.
Topics: Acetyl Coenzyme A; Acylation; Animals; Catalytic Domain; Ducks; Kinetics; Malonyl Coenzyme A; Phylogeny; Polyketide Synthases; Protein Domains; Substrate Specificity | 2018 |
Increased sesqui- and triterpene production by co-expression of HMG-CoA reductase and biotin carboxyl carrier protein in tobacco (Nicotiana benthamiana).
Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Carrier Proteins; Cytosol; Fatty Acid Synthase, Type II; Fatty Acids; Hydroxymethylglutaryl CoA Reductases; Malonyl Coenzyme A; Monocyclic Sesquiterpenes; Nicotiana; Plant Leaves; Sesquiterpenes; Triterpenes | 2019 |
Enhancing 3-hydroxypropionic acid production in combination with sugar supply engineering by cell surface-display and metabolic engineering of Schizosaccharomyces pombe.
Topics: Acetyl Coenzyme A; Batch Cell Culture Techniques; Carbon; Lactic Acid; Malonyl Coenzyme A; Metabolic Engineering; Metabolic Networks and Pathways; Oxidoreductases; Schizosaccharomyces; Sugars | 2018 |
Improved lovastatin production by inhibiting (+)-geodin biosynthesis in Aspergillus terreus.
Topics: Acetyl Coenzyme A; Aspergillus; Benzofurans; Biosynthetic Pathways; Glycerol; Lactose; Lovastatin; Malonyl Coenzyme A | 2019 |
Transfer of glucose hydrogens via acetyl-CoA, malonyl-CoA, and NADPH to fatty acids during de novo lipogenesis.
Topics: Acetyl Coenzyme A; Animals; Fatty Acids; Glucose; Hydrogen; Lipogenesis; Male; Malonyl Coenzyme A; Mice; Mice, Inbred C57BL; NADP | 2019 |
Model-Assisted Fine-Tuning of Central Carbon Metabolism in Yeast through dCas9-Based Regulation.
Topics: Acetyl Coenzyme A; Biosensing Techniques; Carbon; Computer Simulation; CRISPR-Associated Protein 9; Cytosol; Ethanol; Gene Expression Regulation, Fungal; Genes, Fungal; Glucose; Malonyl Coenzyme A; Metabolic Engineering; Metabolic Flux Analysis; RNA, Guide, Kinetoplastida; Saccharomyces cerevisiae; Synthetic Biology; Transcription, Genetic | 2019 |
Dietary branched-chain amino acid restriction alters fuel selection and reduces triglyceride stores in hearts of Zucker fatty rats.
Topics: Acetyl Coenzyme A; Amino Acids, Branched-Chain; Animals; Diet; Glucose; Male; Malonyl Coenzyme A; Metabolomics; Myocardium; Obesity; Palmitates; Protein Kinases; Rats; Rats, Zucker; Triglycerides | 2020 |
A Simple and Direct Assay for Monitoring Fatty Acid Synthase Activity and Product-Specificity by High-Resolution Mass Spectrometry.
Topics: Acetyl Coenzyme A; Animals; Cattle; Enzyme Assays; Fatty Acid Synthase, Type I; Lipidomics; Malonyl Coenzyme A; Mass Spectrometry; NADP; Substrate Specificity | 2020 |
Tartronic acid promotes de novo lipogenesis and inhibits CPT-1β by upregulating acetyl-CoA and malonyl-CoA.
Topics: 3T3-L1 Cells; Acetyl Coenzyme A; Animals; Carnitine O-Palmitoyltransferase; Diet, High-Fat; Lipogenesis; Male; Malonyl Coenzyme A; Mice; Mice, Inbred C57BL; Tartronates; Up-Regulation | 2020 |
Ustethylin Biosynthesis Implies Phenethyl Derivative Formation in
Topics: Acetyl Coenzyme A; Aspergillus; Malonyl Coenzyme A; Methyltransferases; Molecular Structure; Oxidoreductases; Polyketide Synthases | 2020 |
Applied evolution: Dual dynamic regulations-based approaches in engineering intracellular malonyl-CoA availability.
Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Malonyl Coenzyme A; Metabolic Engineering; Polyketides | 2021 |
Increasing Lovastatin Production by Re-routing the Precursors Flow of Aspergillus terreus via Metabolic Engineering.
Topics: Acetyl Coenzyme A; Aspergillus; Benzofurans; Biosynthetic Pathways; Fermentation; Glycerol; Kinetics; Lactose; Lovastatin; Malonyl Coenzyme A; Metabolic Engineering | 2022 |
Paradoxical activation of transcription factor SREBP1c and de novo lipogenesis by hepatocyte-selective ATP-citrate lyase depletion in obese mice.
Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Animals; ATP Citrate (pro-S)-Lyase; Diabetes Mellitus, Type 2; Hepatocytes; Lipogenesis; Liver; Malonyl Coenzyme A; Mice; Mice, Obese; Palmitates; Sterol Regulatory Element Binding Protein 1 | 2022 |
Targeting peroxisomal fatty acid oxidation improves hepatic steatosis and insulin resistance in obese mice.
Topics: Acetyl Coenzyme A; Acetylcarnitine; Animals; Diabetes Mellitus, Experimental; Fatty Acids; Fatty Liver; Insulin Resistance; Liver; Malonyl Coenzyme A; Mice; Mice, Obese; Obesity; Oxidation-Reduction | 2023 |
Direct Utilization of Peroxisomal Acetyl-CoA for the Synthesis of Polyketide Compounds in
Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Malonyl Coenzyme A; Polyketides; Saccharomyces cerevisiae | 2023 |
Quantitative Analysis of Acetyl-CoA, Malonyl-CoA, and Succinyl-CoA in Myocytes.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Humans; Malonyl Coenzyme A; Muscle Cells | 2023 |