Page last updated: 2024-08-17

acetyl coenzyme a and lactic acid

acetyl coenzyme a has been researched along with lactic acid in 83 studies

Research

Studies (83)

TimeframeStudies, this research(%)All Research%
pre-19906 (7.23)18.7374
1990's18 (21.69)18.2507
2000's22 (26.51)29.6817
2010's32 (38.55)24.3611
2020's5 (6.02)2.80

Authors

AuthorsStudies
Jeffrey, FM; Malloy, CR; Sherry, AD; Thompson, JR1
Chicco, A; Gutman, R; Lombardo, YB1
Sahlin, K1
Marsac, C; Stansbie, D; Wallace, SJ1
Ogata, M; Yagi, T1
Takagi, D; Takeyama, N; Tanaka, T1
Chandramouli, V; Kosugi, K; Kumaran, K; Landau, BR; Schumann, WC; Scofield, RF1
Kosugi, K; Kumaran, K; Landau, BR; Schumann, WC; Scofield, RF1
Geelen, MJ1
Forgo, P; Kover, KE; Podanyi, B; Sumegi, B1
Katz, J; Lee, WN; Wals, P1
Friolet, R; Hoppeler, H; Krähenbühl, S1
Besson, C; Demigne, C; Morand, C; Remesy, C1
Argilés, JM; Domènech, M; López-Soriano, FJ1
Fuchs, G; Strauss, G1
Beylot, M; Diraison, F; Pachiaudi, C1
Jeffrey, FM; Malloy, CR; Sherry, AD; Solomon, MA; Storey, CJ1
Dyck, DJ; Peters, SJ; Spriet, LL; Wendling, PS1
Bertocci, LA; Jones, JG; Malloy, CR; Thomas, GD; Victor, RG1
Aasly, J; Bakken, IJ; Sonnewald, U; Unsgård, G; White, LR1
Asano, N; Miwa, I; Taniguchi, S; Tomino, F1
Bauer, Z; Fuchs, G; Gad'on, N; Huber, H; Menendez, C; Stetter, KO1
Heigenhauser, GJ; Hultman, E; Jones, NL; Matsos, MP; Putman, CT1
Dominguez, LJ; Ofenstein, JP; Sarnaik, AP; Sowers, JR1
Alcaraz, G; Cachon, R; Diviès, C; Riondet, C; Waché, Y1
Comte, B; Poirier, M; Rosiers, CD; Vincent, G1
Heigenhauser, GJ; Jones, NL; Spriet, LL; St Amand, TA1
Barbee, RW; Kline, JA; Lopaschuk, GD; Thornton, LR; Watts, JA1
Heigenhauser, GJ; Hollidge-Horvat, MG; Hultman, E; Jones, NL; Matsos, MP; Parolin, ML; Spriet, LL1
Friars, D; Graham, TE; Greer, F1
Brand, A; Leibfritz, D; Richter-Landsberg, C; Zwingmann, C1
Bacher, A; Eisenreich, W; Farfsing, J; Fuchs, G; Gad'On, N; Herter, S; Rieder, C1
Argo, BM; Hyyti, O; Krueger, JJ; Ning, XH; Portman, MA1
Evans, MK; Heigenhauser, GJ; Savasi, I; Spriet, LL1
Brocks, C; Chatham, JC; Lloyd, S1
Hazell, AS; Leibfritz, D; Zwingmann, C1
Moriwaki, Y; Takahashi, S; Yamamoto, T1
Carvalho, RA; Castro, MM; Fonseca, CP; Geraldes, CF; Jeffrey, FM; Jones, JG; Montezinho, LP1
Onay-Besikci, A1
Fong, SS; Hua, Q; Joyce, AR; Palsson, BØ1
Berg, IA; Buckel, W; Fuchs, G; Kockelkorn, D1
Buroker, NE; Chung, Y; Ge, M; Hyyti, OM; Jue, T; Ning, XH; Olson, AK; Portman, MA1
Doherty, TJ; Gurd, BJ; Heigenhauser, GJ; Kowalchuk, JM; LeBlanc, PJ; Paterson, DH; Peters, SJ1
Bigrigg, JK; Heigenhauser, GJ; Inglis, JG; LeBlanc, PJ; Peters, SJ1
Brecht, V; Fuchs, G; Müller, M; Zarzycki, J1
Andersen, MR; Frisvad, JC; Lametsch, R; Nielsen, PV; Sørensen, LM1
Bielarczyk, H; Jankowska-Kulawy, A; Pawełczyk, T; Szutowicz, A; Wróblewska, M1
Blankenship, RE; Tang, KH1
Henry, O; Jolicoeur, M; Kamen, A1
Ertel, A; Flomenberg, N; Howell, A; Knudsen, ES; Lin, Z; Lisanti, MP; Martinez-Outschoorn, UE; Pavlides, S; Pestell, RG; Prisco, M; Sotgia, F; Tsirigos, A; Wang, C1
Fukuda, J; Hatazawa, T; Kano, K; Sakai, H; Shirai, O; Tokita, Y; Tsujimura, S1
Bruchelt, G; Deubzer, B; Handgretinger, R; Krampen, L; Kuçi, Z; Niewisch, MR; Sautter, M; Wolburg, H1
Basu, R; Clanachan, A; Gandhi, M; Kassiri, Z; Lopaschuk, GD; Mori, J; Oudit, GY; Zhabyeyev, P1
Berg, IA; Fuchs, G1
Chan, SH; Jensen, PR; Nørregaard, L; Solem, C1
Chang, S; Chen, X; Jiang, S; Ke, W; Luo, S; Wu, X; Yang, P; Zheng, Z1
Amaral, AI; Hadera, MG; Kotter, MR; Sonnewald, U; Tavares, JM1
Ding, Y; Liu, H; Liu, M; Xian, M; Yao, L; Zhao, G1
Cho, HY; Cho, KM; Kang, CD; Lee, S; Park, JS; Song, JY; Yang, D1
Cucchi, D; Haas, R; Macdougall, CE; Mauro, C; Pucino, V; Smith, J1
Duan, CY; Li, C; Liu, LB; Mao, X; Wang, JY; Wang, ZJ; Zhang, GF1
Lisanti, MP; Martinez-Outschoorn, UE; Peiris-Pagés, M; Pestell, RG; Sotgia, F1
Cheng, Y; Deng, Z; Fu, S; Li, X; Liu, T; Liu, Z; Tan, G; Ye, Z; Zhu, F1
Han, X; Hashimoto, Y; Satoh, T; Satoh, Y; Taguchi, S; Tajima, K1
Hadera, MG; I Amaral, A; Kotter, M; Sonnewald, U1
Antoniewicz, MR; Crown, SB; Kelleher, JK; Muoio, DM; Rouf, R1
Dean, B; Scarr, E; Thomas, N; Udawela, M1
Ansari, IH; Burant, CF; El Azzouny, M; Jitrapakdee, S; Longacre, MJ; MacDonald, MJ; Phannasil, P; Rattanapornsompong, K1
Beumer, JH; Christner, SM; Davidson, NE; Hahm, ER; Kim, SH; Pore, SK; Roy, R; Samanta, SK; Sehrawat, A; Shuai, Y; Singh, KB; Singh, SV1
Chen, H; Ding, Y; Liu, H; Liu, M; Xian, M; Zhao, G; Zhao, Z1
Jin, YS; Kwak, S1
Higuchi, Y; Maeda, Y; Suyama, A; Takegawa, K; Urushihara, M1
He, Q; Huang, F; Li, J; Shao, Y; Wang, T; Yao, W1
Hu, X; Tam, KY; Zhang, W; Zhou, W1
Hirata, Y; Kishida, M; Kondo, A; Konishi, R; Matsumoto, T; Otomo, C; Ozaki, A; Takayama, S; Tanaka, T1
Abdel-Aziz, W; Abdel-Latif, HM; Aboonq, MS; Ahmed, NS; Almaramhy, HH; Ayat, M; Baghdadi, H; El Sayed, SM; El-Sawy, SA; Elshazley, M; Ibrahim, W; Mahmoud, AA1
Bai, C; Chu, Q; Li, B; Liu, M; Qiu, L; Ruan, Y; Wang, Y; Yang, C1
Chen, T; Cui, Z; Mao, Y; Wang, B; Wang, Z; Zhang, X; Zhang, Z1
Chen, K; Chen, M; Gao, M; Hao, Z; Li, L; Liu, X; Liu, Z; Long, Q; Ma, B; Nie, J; Pan, G; Pei, D; Qi, J; Wang, T; Wu, Y; Xing, G; Ye, D; Yuan, H; Zhang, C; Zhang, J; Zhao, D; Zhou, Y1
Angus, DC; Bakalov, V; Chang, CH; Deshpande, R; Kaynar, AM; Le Moyec, L; Maloy, AL; Reyes-Uribe, L; Shapiro, SD; Wendell, SG1
Chen, AN; Fu, JT; Geng, XM; Luo, Y; Shi, JP; Yang, J; Yang, YH1
Cao, F; Cheng, S; He, Z; Liu, W; Varrone, C; Yu, D; Yue, X; Zhou, A1
Matsumoto, T; Ogino, H; Otani, T; Yamada, R1

Reviews

7 review(s) available for acetyl coenzyme a and lactic acid

ArticleYear
Disorders of the pyruvate dehydrogenase complex.
    Journal of inherited metabolic disease, 1986, Volume: 9, Issue:2

    Topics: Acetyl Coenzyme A; Acetyltransferases; Acidosis; Brain; Carbon Dioxide; Child; Child, Preschool; Coenzyme A; Cranial Nerves; Dihydrolipoamide Dehydrogenase; Dihydrolipoyllysine-Residue Acetyltransferase; Facial Bones; Feedback; Humans; Lactates; Lactic Acid; Leigh Disease; Molecular Weight; Movement Disorders; NAD; Nervous System Diseases; Phosphoric Monoester Hydrolases; Pyruvate Decarboxylase; Pyruvate Dehydrogenase Complex; Pyruvate Dehydrogenase Complex Deficiency Disease; Pyruvates; Pyruvic Acid; Spectrophotometry

1986
Effect of ethanol on metabolism of purine bases (hypoxanthine, xanthine, and uric acid).
    Clinica chimica acta; international journal of clinical chemistry, 2005, Volume: 356, Issue:1-2

    Topics: Acetyl Coenzyme A; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Ethanol; Humans; Hyperuricemia; Hypoxanthine; Lactic Acid; NAD; Oxidation-Reduction; Uric Acid; Xanthine; Xanthine Dehydrogenase

2005
Unfamiliar metabolic links in the central carbon metabolism.
    Journal of biotechnology, 2014, Dec-20, Volume: 192 Pt B

    Topics: Acetyl Coenzyme A; Archaea; Bacteria; Carbon; Hydroxybutyrates; Lactic Acid; Metabolic Engineering; Metabolic Networks and Pathways

2014
Intermediates of Metabolism: From Bystanders to Signalling Molecules.
    Trends in biochemical sciences, 2016, Volume: 41, Issue:5

    Topics: Acetyl Coenzyme A; Cell Communication; Citric Acid Cycle; Cytokines; Endothelial Cells; Fatty Acids; Glycolysis; Humans; Immunity, Innate; Lactic Acid; Macrophages; Neurons; Signal Transduction; Succinic Acid; T-Lymphocytes

2016
Cancer metabolism: a therapeutic perspective.
    Nature reviews. Clinical oncology, 2017, Volume: 14, Issue:1

    Topics: Acetyl Coenzyme A; Adaptation, Physiological; Amino Acids; Antineoplastic Agents; Antioxidants; Autophagy; Blood Glucose; Energy Metabolism; Epigenomics; Fatty Acids; Genetic Heterogeneity; Glutamic Acid; Glutamine; Humans; Ketone Bodies; Lactic Acid; Lipids; Mitochondria; Mitochondrial Ribosomes; Neoplasms; Nucleic Acids; Oxidative Stress; Pyruvic Acid; TOR Serine-Threonine Kinases; Transcription Factors; Tumor Microenvironment

2017
Production of fuels and chemicals from xylose by engineered Saccharomyces cerevisiae: a review and perspective.
    Microbial cell factories, 2017, May-11, Volume: 16, Issue:1

    Topics: Acetyl Coenzyme A; Aldehyde Reductase; Aldose-Ketose Isomerases; Biofuels; Biotechnology; D-Xylulose Reductase; Ethanol; Fatty Alcohols; Fermentation; Glucose; Lactic Acid; Metabolic Engineering; Saccharomyces cerevisiae; Xylose

2017
Lactylation, a Novel Metabolic Reprogramming Code: Current Status and Prospects.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Acetyl Coenzyme A; Animals; Epigenesis, Genetic; Histones; Humans; Lactic Acid; Tumor Microenvironment

2021

Trials

6 trial(s) available for acetyl coenzyme a and lactic acid

ArticleYear
Relationship between the coenzyme A and the carnitine pools in human skeletal muscle at rest and after exhaustive exercise under normoxic and acutely hypoxic conditions.
    The Journal of clinical investigation, 1994, Volume: 94, Issue:4

    Topics: Acetyl Coenzyme A; Adult; Carnitine; Coenzyme A; Hemodynamics; Humans; Lactates; Lactic Acid; Male; Muscle, Skeletal; Oxygen; Physical Exertion

1994
Pyruvate overrides inhibition of PDH during exercise after a low-carbohydrate diet.
    American journal of physiology. Endocrinology and metabolism, 2000, Volume: 279, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acetyl Coenzyme A; Acetylcarnitine; Adult; Blood Glucose; Dietary Carbohydrates; Exercise Test; Fatty Acids, Nonesterified; Food, Formulated; Glycerol; Glycerophosphates; Glycogen; Humans; Insulin; Lactic Acid; Male; Muscle, Skeletal; Physical Exertion; Protein Kinases; Protein Serine-Threonine Kinases; Pulmonary Gas Exchange; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Reference Values

2000
Effects of PDH activation by dichloroacetate in human skeletal muscle during exercise in hypoxia.
    American journal of physiology. Endocrinology and metabolism, 2000, Volume: 279, Issue:4

    Topics: Acetyl Coenzyme A; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adult; Blood Glucose; Blood Pressure; Dichloroacetic Acid; Glycogen; Glycolysis; Heart Rate; Humans; Hypoxia; Lactic Acid; Male; Muscle, Skeletal; Oxygen Consumption; Phosphocreatine; Phosphorylases; Physical Exertion; Pyruvate Dehydrogenase Complex; Respiratory Function Tests

2000
Comparison of caffeine and theophylline ingestion: exercise metabolism and endurance.
    Journal of applied physiology (Bethesda, Md. : 1985), 2000, Volume: 89, Issue:5

    Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Blood Glucose; Caffeine; Central Nervous System Stimulants; Citric Acid; Cyclic AMP; Energy Metabolism; Epinephrine; Fatty Acids, Nonesterified; Glucose-6-Phosphatase; Glycerol; Glycogen; Humans; Lactic Acid; Male; Muscle, Skeletal; Norepinephrine; Oxygen Consumption; Physical Endurance; Theophylline; Vasodilator Agents; Xanthines

2000
Effects of acetate infusion and hyperoxia on muscle substrate phosphorylation after onset of moderate exercise.
    American journal of physiology. Endocrinology and metabolism, 2001, Volume: 281, Issue:6

    Topics: Acetates; Acetyl Coenzyme A; Acetylcarnitine; Adenosine Diphosphate; Adenosine Monophosphate; Adult; Exercise; Exercise Test; Glycolysis; Humans; Hyperoxia; Lactic Acid; Male; Muscle, Skeletal; Oxidative Phosphorylation; Oxygen Consumption; Phosphocreatine; Pyruvate Dehydrogenase Complex; Pyruvic Acid

2001
Carbohydrate refeeding after a high-fat diet rapidly reverses the adaptive increase in human skeletal muscle PDH kinase activity.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 297, Issue:3

    Topics: 3-Hydroxybutyric Acid; Acetyl Coenzyme A; Adaptation, Physiological; Adenosine Triphosphate; Blood Glucose; Dietary Carbohydrates; Dietary Fats; Fatty Acids, Nonesterified; Glycerol; Humans; Insulin; Lactic Acid; Male; Muscle, Skeletal; Phosphocreatine; Phosphorylation; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase (Lipoamide); Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Time Factors; Young Adult

2009

Other Studies

70 other study(ies) available for acetyl coenzyme a and lactic acid

ArticleYear
Contribution of exogenous substrates to acetyl coenzyme A: measurement by 13C NMR under non-steady-state conditions.
    Biochemistry, 1990, Jul-24, Volume: 29, Issue:29

    Topics: Acetates; Acetic Acid; Acetyl Coenzyme A; Animals; Binding, Competitive; Carbon Isotopes; Energy Metabolism; Glucose; Glutamates; Glutamic Acid; In Vitro Techniques; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Myocardium; Perfusion; Rats; Rats, Inbred Strains

1990
Biochemical abnormalities in the heart of rats fed a sucrose-rich diet: is the low activity of the pyruvate dehydrogenase complex a result of increased fatty acid oxidation?
    Metabolism: clinical and experimental, 1991, Volume: 40, Issue:1

    Topics: Acetyl Coenzyme A; Animals; Citrates; Citric Acid; Dietary Carbohydrates; Epoxy Compounds; Fatty Acids; Glucose-6-Phosphate; Glucosephosphates; Heart; Hypoglycemic Agents; Lactates; Lactic Acid; Male; Myocardium; Nucleotides; Oxidation-Reduction; Papillary Muscles; Pyruvate Dehydrogenase Complex; Rats; Sucrose

1991
Muscle carnitine metabolism during incremental dynamic exercise in humans.
    Acta physiologica Scandinavica, 1990, Volume: 138, Issue:3

    Topics: Acetyl Coenzyme A; Acetylcarnitine; Adult; Carnitine; Exercise; Humans; Lactates; Lactic Acid; Male; Muscles; Oxygen Consumption; Pyruvates; Pyruvic Acid

1990
Pyruvate dehydrogenase and the path of lactate degradation in Desulfovibrio vulgaris Miyazaki F.
    Journal of biochemistry, 1986, Volume: 100, Issue:2

    Topics: Acetyl Coenzyme A; Cytochrome c Group; Desulfovibrio; Flavin Mononucleotide; Hydrogen-Ion Concentration; Ketone Oxidoreductases; Kinetics; Lactates; Lactic Acid; Molecular Weight; Pyruvate Dehydrogenase Complex; Pyruvate Synthase; Pyruvates; Pyruvic Acid; Substrate Specificity; Temperature

1986
Biochemical effects of acute stress on energy metabolism in liver damaged rats.
    Physiology & behavior, 1987, Volume: 40, Issue:1

    Topics: Acetyl Coenzyme A; Animals; Chemical and Drug Induced Liver Injury; Cyclic AMP; Cyclic GMP; Energy Metabolism; Galactosamine; Ketone Bodies; Lactates; Lactic Acid; Liver Diseases; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Stress, Physiological

1987
Pathways of acetone's metabolism in the rat.
    The Journal of biological chemistry, 1986, Mar-25, Volume: 261, Issue:9

    Topics: Acetone; Acetyl Coenzyme A; Animals; Diabetes Mellitus, Experimental; Diabetic Ketoacidosis; Female; Hydroxybutyrates; Lactates; Lactic Acid; Liver; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains

1986
Quantitative estimation of the pathways followed in the conversion to glycogen of glucose administered to the fasted rat.
    The Journal of biological chemistry, 1985, Jul-25, Volume: 260, Issue:15

    Topics: Acetyl Coenzyme A; Animals; Carbon Radioisotopes; Fasting; Glucose; Lactates; Lactic Acid; Liver; Liver Glycogen; Male; Rats; Rats, Inbred Strains; Tritium

1985
Effects of fenfluramine on hepatic intermediary metabolism.
    Biochemical pharmacology, 1983, Nov-15, Volume: 32, Issue:22

    Topics: Acetyl Coenzyme A; Alanine; Animals; Fatty Acids; Fenfluramine; Gluconeogenesis; Glycolysis; Ketone Bodies; Lactates; Lactic Acid; Liver; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains

1983
Metabolism of [3-13C]pyruvate and [3-13C]propionate in normal and ischaemic rat heart in vivo: 1H- and 13C-NMR studies.
    The Biochemical journal, 1995, Nov-15, Volume: 312 ( Pt 1)

    Topics: Acetyl Coenzyme A; Alanine; Animals; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Myocardial Ischemia; Myocardium; Propionates; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar

1995
Isotopomer studies of gluconeogenesis and the Krebs cycle with 13C-labeled lactate.
    The Journal of biological chemistry, 1993, Dec-05, Volume: 268, Issue:34

    Topics: Acetyl Coenzyme A; Alanine; Animals; Blood Glucose; Carbon Dioxide; Carbon Isotopes; Citric Acid Cycle; Gas Chromatography-Mass Spectrometry; Gluconeogenesis; Glucose; Glutamates; Glutamic Acid; Glutamine; Isotope Labeling; Lactates; Lactic Acid; Liver; Male; Oxaloacetates; Phosphoenolpyruvate; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley

1993
Importance of the modulation of glycolysis in the control of lactate metabolism by fatty acids in isolated hepatocytes from fed rats.
    Archives of biochemistry and biophysics, 1994, Volume: 309, Issue:2

    Topics: Acetyl Coenzyme A; Animals; Butyrates; Butyric Acid; Caprylates; Citrates; Citric Acid; Fatty Acids; Fructosediphosphates; Glycolysis; Ketone Bodies; Lactates; Lactic Acid; Liver; Male; Oleic Acid; Oleic Acids; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar

1994
Alanine as a lipogenic precursor in isolated hepatocytes from obese Zucker rats.
    Cellular and molecular biology (Noisy-le-Grand, France), 1993, Volume: 39, Issue:6

    Topics: Acetyl Coenzyme A; Alanine; Alanine Transaminase; Animals; Cells, Cultured; Citrates; Coumaric Acids; Fatty Acids; Glucose; Lactates; Lactic Acid; Leucine; Lipids; Liver; Liver Glycogen; Male; Mitochondria, Liver; Obesity; Pyruvates; Pyruvic Acid; Rats; Rats, Zucker

1993
Enzymes of a novel autotrophic CO2 fixation pathway in the phototrophic bacterium Chloroflexus aurantiacus, the 3-hydroxypropionate cycle.
    European journal of biochemistry, 1993, Aug-01, Volume: 215, Issue:3

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Bacteria; Carbon Dioxide; Enzymes; Glyoxylates; Lactates; Lactic Acid

1993
In vivo measurement of plasma cholesterol and fatty acid synthesis with deuterated water: determination of the average number of deuterium atoms incorporated.
    Metabolism: clinical and experimental, 1996, Volume: 45, Issue:7

    Topics: Acetyl Coenzyme A; Animals; Blood Chemical Analysis; Blood Glucose; Cholesterol; Deuterium; Deuterium Oxide; Fatty Acids; Gas Chromatography-Mass Spectrometry; Lactates; Lactic Acid; Liver; Male; Palmitates; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Triglycerides

1996
Substrate selection early after reperfusion of ischemic regions in the working rabbit heart.
    Magnetic resonance in medicine, 1996, Volume: 35, Issue:6

    Topics: Acetoacetates; Acetyl Coenzyme A; Animals; Butyrates; Fatty Acids, Nonesterified; Glucose; Glutamates; In Vitro Techniques; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Myocardial Reperfusion; Myocardium; Rabbits

1996
Effect of high FFA on glycogenolysis in oxidative rat hindlimb muscles during twitch stimulation.
    The American journal of physiology, 1996, Volume: 270, Issue:4 Pt 2

    Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Animals; Citric Acid; Electric Stimulation; Fatty Acids, Nonesterified; Glucose; Glycogen; Hindlimb; Lactic Acid; Male; Muscle Contraction; Muscles; Oxidation-Reduction; Oxygen Consumption; Phosphocreatine; Rats; Rats, Sprague-Dawley

1996
Oxidation of lactate and acetate in rat skeletal muscle: analysis by 13C-nuclear magnetic resonance spectroscopy.
    Journal of applied physiology (Bethesda, Md. : 1985), 1997, Volume: 83, Issue:1

    Topics: Acetates; Acetyl Coenzyme A; Animals; Electric Stimulation; Female; Hindlimb; Lactic Acid; Magnetic Resonance Spectroscopy; Muscle Contraction; Muscle, Skeletal; Oxidation-Reduction; Rats; Rats, Sprague-Dawley

1997
[U-13C] aspartate metabolism in cultured cortical astrocytes and cerebellar granule neurons studied by NMR spectroscopy.
    Glia, 1998, Volume: 23, Issue:3

    Topics: Acetyl Coenzyme A; Animals; Aspartic Acid; Astrocytes; Carbon Isotopes; Cells, Cultured; Cerebellar Cortex; Cerebral Cortex; Citric Acid Cycle; Energy Metabolism; Glucose; Glycolysis; Iodoacetates; Iodoacetic Acid; Lactic Acid; Magnetic Resonance Spectroscopy; Mice; Neurons; Pyruvates

1998
Potentiation of glucose-induced insulin secretion by fagomine, a pseudo-sugar isolated from mulberry leaves.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1998, Volume: 30, Issue:11

    Topics: Acetyl Coenzyme A; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Drug Synergism; Enzyme Inhibitors; Female; Glucose; Glyceraldehyde; Glyceraldehyde 3-Phosphate; Glycolysis; Imino Pyranoses; Insulin; Insulin Secretion; Islets of Langerhans; Lactic Acid; Oligo-1,6-Glucosidase; Piperidines; Rats; Rats, Wistar

1998
Presence of acetyl coenzyme A (CoA) carboxylase and propionyl-CoA carboxylase in autotrophic Crenarchaeota and indication for operation of a 3-hydroxypropionate cycle in autotrophic carbon fixation.
    Journal of bacteriology, 1999, Volume: 181, Issue:4

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Acyl Coenzyme A; Aerobiosis; Biotin; Carbon Dioxide; Carboxy-Lyases; Chlorobi; Crenarchaeota; Genes, Archaeal; Lactic Acid; Malonyl Coenzyme A; Methylmalonyl-CoA Decarboxylase; Peptides; Sequence Homology; Succinic Acid; Sulfolobaceae

1999
Pyruvate dehydrogenase activation in inactive muscle during and after maximal exercise in men.
    The American journal of physiology, 1999, Volume: 276, Issue:3

    Topics: Acetyl Coenzyme A; Acetylcarnitine; Adult; Bicycling; Enzyme Activation; Exercise; Humans; Lactic Acid; Male; Muscle, Skeletal; Physical Endurance; Pyruvate Dehydrogenase Complex

1999
Effects of insulin and metformin on glucose metabolism in rat vascular smooth muscle.
    Metabolism: clinical and experimental, 1999, Volume: 48, Issue:11

    Topics: Acetyl Coenzyme A; Animals; Glucose; Hypoglycemic Agents; Insulin; Lactic Acid; Male; Metformin; Mitochondria, Muscle; Muscle, Smooth, Vascular; Oxidation-Reduction; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Rats; Rats, Sprague-Dawley

1999
Extracellular oxidoreduction potential modifies carbon and electron flow in Escherichia coli.
    Journal of bacteriology, 2000, Volume: 182, Issue:3

    Topics: Acetic Acid; Acetyl Coenzyme A; Alcohol Dehydrogenase; Carbon; Carbon Dioxide; Electrons; Escherichia coli; Ethanol; Fermentation; Formates; Lactic Acid; Models, Chemical; NAD; Oxaloacetates; Oxidation-Reduction; Phosphoenolpyruvate; Phosphoenolpyruvate Carboxylase; Pyruvate Kinase; Succinic Acid

2000
Citrate release by perfused rat hearts: a window on mitochondrial cataplerosis.
    American journal of physiology. Endocrinology and metabolism, 2000, Volume: 278, Issue:5

    Topics: Acetyl Coenzyme A; Animals; Caprylates; Citric Acid; Energy Metabolism; Gas Chromatography-Mass Spectrometry; Glucose; In Vitro Techniques; Indicator Dilution Techniques; Insulin; L-Lactate Dehydrogenase; Lactic Acid; Male; Mitochondria, Heart; Myocardium; Oxaloacetic Acid; Pyruvic Acid; Rats; Rats, Sprague-Dawley

2000
Lactate improves cardiac efficiency after hemorrhagic shock.
    Shock (Augusta, Ga.), 2000, Volume: 14, Issue:2

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Cardiac Output; Citric Acid Cycle; Energy Metabolism; Enzyme Activation; Glucose; Heart; Heart Function Tests; Lactic Acid; Myocardium; Oxygen Consumption; Palmitic Acid; Perfusion; Pyruvate Dehydrogenase Complex; Rats; Shock, Hemorrhagic

2000
NMR spectroscopic study on the metabolic fate of [3-(13)C]alanine in astrocytes, neurons, and cocultures: implications for glia-neuron interactions in neurotransmitter metabolism.
    Glia, 2000, Volume: 32, Issue:3

    Topics: Acetyl Coenzyme A; Alanine; Alanine Transaminase; Animals; Aspartic Acid; Astrocytes; Carbon Isotopes; Cell Communication; Cells, Cultured; Citric Acid Cycle; gamma-Aminobutyric Acid; Glutamate Dehydrogenase; Glutamic Acid; Glutamine; Lactic Acid; Magnetic Resonance Spectroscopy; Neurons; Neurotransmitter Agents; Protein Transport; Rats; Rats, Wistar

2000
Autotrophic CO(2) fixation by Chloroflexus aurantiacus: study of glyoxylate formation and assimilation via the 3-hydroxypropionate cycle.
    Journal of bacteriology, 2001, Volume: 183, Issue:14

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Carbon Dioxide; Chlorobi; Glycine; Glyoxylates; Lactic Acid; Malates

2001
Triidothyronine and epinephrine rapidly modify myocardial substrate selection: a (13)C isotopomer analysis.
    American journal of physiology. Endocrinology and metabolism, 2001, Volume: 281, Issue:5

    Topics: Acetoacetates; Acetyl Coenzyme A; Animals; Citric Acid Cycle; Epinephrine; Fatty Acids, Nonesterified; Glucose; Heart; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Myocardium; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Triiodothyronine; Ventricular Function, Left

2001
Differential modulation of glucose, lactate, and pyruvate oxidation by insulin and dichloroacetate in the rat heart.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 285, Issue:1

    Topics: Acetyl Coenzyme A; Alanine; Animals; Buffers; Citric Acid Cycle; Dichloroacetic Acid; Energy Metabolism; Glucose; Heart; Heart Function Tests; Heart Rate; Hypoglycemic Agents; In Vitro Techniques; Insulin; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Myocardium; Oxidation-Reduction; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Ventricular Function, Left

2003
Energy metabolism in astrocytes and neurons treated with manganese: relation among cell-specific energy failure, glucose metabolism, and intercellular trafficking using multinuclear NMR-spectroscopic analysis.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2003, Volume: 23, Issue:6

    Topics: Acetyl Coenzyme A; Animals; Astrocytes; Carbon Isotopes; Cells, Cultured; Citric Acid Cycle; Energy Metabolism; Glucose; Glycolysis; Lactic Acid; Magnetic Resonance Spectroscopy; Manganese; Manganese Poisoning; Neurons; Osmotic Pressure; Protein Transport; Pyruvate Carboxylase; Pyruvate Dehydrogenase Complex; Rats; Rats, Sprague-Dawley

2003
Tricarboxylic acid cycle inhibition by Li+ in the human neuroblastoma SH-SY5Y cell line: a 13C NMR isotopomer analysis.
    Neurochemistry international, 2005, Volume: 47, Issue:6

    Topics: Acetyl Coenzyme A; Antimanic Agents; Bipolar Disorder; Brain; Brain Chemistry; Carbon Isotopes; Cell Line, Tumor; Cell Survival; Citrate (si)-Synthase; Citric Acid Cycle; Dose-Response Relationship, Drug; Down-Regulation; Energy Metabolism; Feedback, Physiological; Glucose; Humans; Lactic Acid; Lithium; Magnetic Resonance Spectroscopy; Neuroblastoma; Neurons; Pyruvic Acid

2005
Impact of lactate in the perfusate on function and metabolic parameters of isolated working rat heart.
    Molecular and cellular biochemistry, 2007, Volume: 296, Issue:1-2

    Topics: Acetyl Coenzyme A; Animals; Fatty Acids; Glucose; Glycolysis; Heart; Lactic Acid; Male; Myocardium; Oxidation-Reduction; Rats; Rats, Sprague-Dawley

2007
Metabolic characterization of Escherichia coli strains adapted to growth on lactate.
    Applied and environmental microbiology, 2007, Volume: 73, Issue:14

    Topics: Acetyl Coenzyme A; Biomass; Carbon; Carbon Isotopes; Escherichia coli; Gene Expression Regulation, Bacterial; Gluconeogenesis; Lactic Acid; Metabolic Networks and Pathways; Oxaloacetic Acid; Phosphoenolpyruvate; Pyruvic Acid; Transcription, Genetic

2007
A 3-hydroxypropionate/4-hydroxybutyrate autotrophic carbon dioxide assimilation pathway in Archaea.
    Science (New York, N.Y.), 2007, Dec-14, Volume: 318, Issue:5857

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Acyl Coenzyme A; Amino Acid Sequence; Anaerobiosis; Archaea; Autotrophic Processes; Bicarbonates; Carbon Dioxide; Genes, Archaeal; Hydro-Lyases; Hydroxybutyrates; Kinetics; Lactic Acid; Metabolic Networks and Pathways; Molecular Sequence Data; Oxidation-Reduction; Photosynthesis; Phylogeny; Sulfolobaceae

2007
Cardioselective dominant-negative thyroid hormone receptor (Delta337T) modulates myocardial metabolism and contractile efficiency.
    American journal of physiology. Endocrinology and metabolism, 2008, Volume: 295, Issue:2

    Topics: Acetoacetates; Acetyl Coenzyme A; Animals; Citric Acid Cycle; Fatty Acids, Nonesterified; Glucose Transporter Type 4; Hexokinase; Immunoblotting; In Vitro Techniques; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Transgenic; Myocardial Contraction; Myocardium; Oxygen Consumption; Succinate Dehydrogenase; Thyroid Hormone Receptors beta

2008
Prior heavy exercise elevates pyruvate dehydrogenase activity and muscle oxygenation and speeds O2 uptake kinetics during moderate exercise in older adults.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 297, Issue:3

    Topics: Acetyl Coenzyme A; Adaptation, Physiological; Adenosine Diphosphate; Adenosine Triphosphate; Age Factors; Aged; Exercise; Humans; Kinetics; Lactic Acid; Male; Mitochondria, Muscle; Muscle, Skeletal; Oxygen; Oxygen Consumption; Phosphocreatine; Pulmonary Ventilation; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Regional Blood Flow; Spectroscopy, Near-Infrared; Up-Regulation

2009
Identifying the missing steps of the autotrophic 3-hydroxypropionate CO2 fixation cycle in Chloroflexus aurantiacus.
    Proceedings of the National Academy of Sciences of the United States of America, 2009, Dec-15, Volume: 106, Issue:50

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Acyl Coenzyme A; Autotrophic Processes; Carbon Dioxide; Chloroflexus; Glyoxylates; Lactic Acid; Metabolic Networks and Pathways; Methylmalonyl-CoA Decarboxylase

2009
Proteome analysis of Aspergillus niger: lactate added in starch-containing medium can increase production of the mycotoxin fumonisin B2 by modifying acetyl-CoA metabolism.
    BMC microbiology, 2009, Dec-10, Volume: 9

    Topics: Acetyl Coenzyme A; Aspergillus niger; Chromatography, High Pressure Liquid; Cluster Analysis; Culture Media; Electrophoresis, Gel, Two-Dimensional; Fumonisins; Lactic Acid; Mycotoxins; Principal Component Analysis; Proteome; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spores, Fungal; Starch; Tandem Mass Spectrometry

2009
Acetyl-CoA and acetylcholine metabolism in nerve terminal compartment of thiamine deficient rat brain.
    Journal of neurochemistry, 2010, Volume: 115, Issue:2

    Topics: Acetyl Coenzyme A; Acetylcholine; Animals; Brain; Citric Acid; Ketoglutarate Dehydrogenase Complex; Ketoglutaric Acids; Ketone Oxidoreductases; Lactic Acid; Male; Models, Biological; Nerve Endings; Pyrithiamine; Pyruvic Acid; Rats; Rats, Wistar; Synaptosomes; Thiamine Deficiency

2010
Both forward and reverse TCA cycles operate in green sulfur bacteria.
    The Journal of biological chemistry, 2010, Nov-12, Volume: 285, Issue:46

    Topics: Acetate Kinase; Acetates; Acetyl Coenzyme A; ATP Citrate (pro-S)-Lyase; Autotrophic Processes; Bacterial Proteins; Biomass; Carbon; Carbon Isotopes; Chlorobi; Citric Acid Cycle; Coenzyme A Ligases; Gene Expression Regulation, Bacterial; Lactic Acid; Metabolic Networks and Pathways; Models, Biological; Molecular Structure; Pyruvic Acid; Reverse Transcriptase Polymerase Chain Reaction

2010
Unraveling the metabolism of HEK-293 cells using lactate isotopomer analysis.
    Bioprocess and biosystems engineering, 2011, Volume: 34, Issue:3

    Topics: Acetyl Coenzyme A; Amino Acids; Carbon; Carbon Isotopes; Cell Line; Cell Survival; Chromatography, Liquid; Citric Acid Cycle; Glucose; Glutamine; HEK293 Cells; Humans; Lactic Acid; Lipids; Magnetic Resonance Spectroscopy; Malates; Oxaloacetic Acid; Pentose Phosphate Pathway

2011
Ketones and lactate increase cancer cell "stemness," driving recurrence, metastasis and poor clinical outcome in breast cancer: achieving personalized medicine via Metabolo-Genomics.
    Cell cycle (Georgetown, Tex.), 2011, Apr-15, Volume: 10, Issue:8

    Topics: Acetyl Coenzyme A; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Citric Acid Cycle; Female; Fibroblasts; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genome-Wide Association Study; Genomics; Glycolysis; Humans; Ketones; Lactic Acid; Metabolomics; Mitochondria; Neoplasm Metastasis; Oxidative Phosphorylation; Precision Medicine; Recurrence; Stem Cells; Treatment Outcome

2011
Micro-coulometric study of bioelectrochemical reaction coupled with TCA cycle.
    Biosensors & bioelectronics, 2012, Apr-15, Volume: 34, Issue:1

    Topics: Acetyl Coenzyme A; Biosensing Techniques; Catalysis; Citric Acid Cycle; Electrochemical Techniques; Electrodes; Electrolysis; Lactic Acid; NAD; NADH Dehydrogenase; Oxidation-Reduction; Succinate Dehydrogenase

2012
Influence of dichloroacetate (DCA) on lactate production and oxygen consumption in neuroblastoma cells: is DCA a suitable drug for neuroblastoma therapy?
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2012, Volume: 29, Issue:3-4

    Topics: Acetyl Coenzyme A; Apoptosis; Cell Line, Tumor; Cell Proliferation; Citric Acid Cycle; Culture Media; Dichloroacetic Acid; Drug Screening Assays, Antitumor; Enzyme Activation; Humans; Lactic Acid; Mitochondria; Neuroblastoma; Oxidative Phosphorylation; Oxygen; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Reactive Oxygen Species

2012
Pressure-overload-induced heart failure induces a selective reduction in glucose oxidation at physiological afterload.
    Cardiovascular research, 2013, Mar-15, Volume: 97, Issue:4

    Topics: Acetyl Coenzyme A; Animals; Echocardiography; Glucose; Glucose Transporter Type 4; Heart Failure; Hypertension; Hypertrophy, Left Ventricular; Lactic Acid; Male; Malonyl Coenzyme A; Mice; Mice, Inbred C57BL; Myocardial Reperfusion Injury; Systole

2013
Acetate kinase isozymes confer robustness in acetate metabolism.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Acetate Kinase; Acetates; Acetyl Coenzyme A; Base Sequence; Conserved Sequence; Genes, Bacterial; Isoenzymes; Kinetics; Lactic Acid; Lactococcus lactis; Maltose; Molecular Sequence Data; Mutation; Phylogeny; Pyruvic Acid; Sequence Homology, Amino Acid; Species Specificity; Terminator Regions, Genetic; Transcription Initiation Site

2014
Metabolic control analysis of L-lactate synthesis pathway in Rhizopus oryzae As 3.2686.
    Bioprocess and biosystems engineering, 2015, Volume: 38, Issue:11

    Topics: Acetyl Coenzyme A; Fungal Proteins; Lactic Acid; Rhizopus

2015
Characterization of glucose-related metabolic pathways in differentiated rat oligodendrocyte lineage cells.
    Glia, 2016, Volume: 64, Issue:1

    Topics: Acetates; Acetyl Coenzyme A; Animals; Carbon Radioisotopes; Cells, Cultured; Citric Acid Cycle; Cytosol; Glucose; Lactic Acid; Malates; Mitochondria; Neural Stem Cells; Oligodendroglia; Oxaloacetic Acid; Pentose Phosphate Pathway; Phosphoenolpyruvate; Pyruvic Acid; Radiopharmaceuticals; Rats, Sprague-Dawley

2016
Deletion of arcA increased the production of acetyl-CoA-derived chemicals in recombinant Escherichia coli.
    Biotechnology letters, 2016, Volume: 38, Issue:1

    Topics: Acetyl Coenzyme A; Bacterial Outer Membrane Proteins; Escherichia coli; Escherichia coli Proteins; Fermentation; Gene Deletion; Gene Expression Regulation, Bacterial; Gene Knockout Techniques; Lactic Acid; Phloroglucinol; Repressor Proteins

2016
Introduction of a bacterial acetyl-CoA synthesis pathway improves lactic acid production in Saccharomyces cerevisiae.
    Metabolic engineering, 2016, Volume: 35

    Topics: Acetyl Coenzyme A; Aldehyde Oxidoreductases; Escherichia coli; Escherichia coli Proteins; Lactic Acid; Saccharomyces cerevisiae

2016
Growth and acid production of Lactobacillus delbrueckii ssp. bulgaricus ATCC 11842 in the fermentation of algal carcass.
    Journal of dairy science, 2016, Volume: 99, Issue:6

    Topics: Acetyl Coenzyme A; Acids; Animals; Fermentation; Lactic Acid; Lactobacillus; Lactobacillus delbrueckii

2016
Evaluation of 3-hydroxypropionate biosynthesis in vitro by partial introduction of the 3-hydroxypropionate/4-hydroxybutyrate cycle from Metallosphaera sedula.
    Journal of industrial microbiology & biotechnology, 2016, Volume: 43, Issue:9

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Biosynthetic Pathways; Carbon Cycle; Kinetics; Lactic Acid; Oxidoreductases; Sodium Oxybate; Sulfolobaceae

2016
In vitro synthesis of polyhydroxyalkanoates using thermostable acetyl-CoA synthetase, CoA transferase, and PHA synthase from thermotorelant bacteria.
    Journal of bioscience and bioengineering, 2016, Volume: 122, Issue:6

    Topics: 3-Hydroxybutyric Acid; Acetate-CoA Ligase; Acetyl Coenzyme A; Acyltransferases; Coenzyme A-Transferases; Enzyme Stability; Hydroxybutyrates; Lactic Acid; Peptococcaceae; Polyesters; Polyhydroxyalkanoates; Temperature; Thermus thermophilus

2016
Oligodendrocytes Do Not Export NAA-Derived Aspartate In Vitro.
    Neurochemical research, 2017, Volume: 42, Issue:3

    Topics: Acetyl Coenzyme A; Acetylation; Animals; Animals, Newborn; Aspartic Acid; Cells, Cultured; Glucose; Hydrolysis; Lactic Acid; Mitochondria; Oligodendroglia; Primary Cell Culture; Prosencephalon; Rats, Sprague-Dawley

2017
Comprehensive metabolic modeling of multiple 13C-isotopomer data sets to study metabolism in perfused working hearts.
    American journal of physiology. Heart and circulatory physiology, 2016, 10-01, Volume: 311, Issue:4

    Topics: Acetyl Coenzyme A; Animals; Carbon Isotopes; Energy Metabolism; Glucose; Isolated Heart Preparation; Lactic Acid; Male; Metabolic Flux Analysis; Metabolic Networks and Pathways; Mice; Models, Biological; Models, Cardiovascular; Myocardium; Oleic Acid; Pyruvic Acid

2016
Evidence for impaired glucose metabolism in the striatum, obtained postmortem, from some subjects with schizophrenia.
    Translational psychiatry, 2016, 11-15, Volume: 6, Issue:11

    Topics: Acetyl Coenzyme A; Adult; Blood Glucose; Case-Control Studies; Corpus Striatum; Energy Metabolism; Female; History, 16th Century; History, 17th Century; Humans; Lactic Acid; Male; Middle Aged; Neural Pathways; Pyruvate Dehydrogenase (Lipoamide); Pyruvic Acid; Receptors, Muscarinic; Reference Values; Schizophrenia

2016
Mass spectrometry analysis shows the biosynthetic pathways supported by pyruvate carboxylase in highly invasive breast cancer cells.
    Biochimica et biophysica acta. Molecular basis of disease, 2017, Volume: 1863, Issue:2

    Topics: Acetyl Coenzyme A; Aspartic Acid; Biosynthetic Pathways; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Citric Acid; Female; Gene Knockdown Techniques; Glycine; Glycolysis; Humans; Lactic Acid; Malates; Mass Spectrometry; Metabolic Networks and Pathways; Neoplasm Invasiveness; Nucleotides; Pyruvate Carboxylase; Pyruvic Acid; Serine

2017
Disease Subtype-Independent Biomarkers of Breast Cancer Chemoprevention by the Ayurvedic Medicine Phytochemical Withaferin A.
    Journal of the National Cancer Institute, 2017, Volume: 109, Issue:6

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetyl Coenzyme A; Aldehyde Dehydrogenase 1 Family; Animals; Apoptosis; Biomarkers, Tumor; Breast Neoplasms; Cell Cycle; Cytokines; Deoxyguanosine; Electron Transport Complex III; Female; Forkhead Transcription Factors; Humans; Ki-67 Antigen; Lactic Acid; Leptin; Malates; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; MCF-7 Cells; Methylnitrosourea; Mice; Mitosis; Mitotic Index; Rats; Receptors, Estrogen; Retinal Dehydrogenase; Retroviridae Infections; Signal Transduction; Tumor Burden; Tumor Virus Infections; Withanolides

2017
Improving the production of acetyl-CoA-derived chemicals in Escherichia coli BL21(DE3) through iclR and arcA deletion.
    BMC microbiology, 2017, 01-07, Volume: 17, Issue:1

    Topics: Acetates; Acetyl Coenzyme A; Bacterial Outer Membrane Proteins; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Gene Knockout Techniques; Glucose; Glyoxylates; Lactic Acid; Metabolic Networks and Pathways; Operon; Phloroglucinol; Repressor Proteins; Sequence Deletion

2017
Production of 3-hydroxypropionic acid via the malonyl-CoA pathway using recombinant fission yeast strains.
    Journal of bioscience and bioengineering, 2017, Volume: 124, Issue:4

    Topics: Acetyl Coenzyme A; Chloroflexus; Cytosol; Heat-Shock Proteins; Kinesins; Lactic Acid; Malonyl Coenzyme A; Oxidoreductases; Promoter Regions, Genetic; Schizosaccharomyces; Schizosaccharomyces pombe Proteins

2017
Acetyl-CoA from inflammation-induced fatty acids oxidation promotes hepatic malate-aspartate shuttle activity and glycolysis.
    American journal of physiology. Endocrinology and metabolism, 2018, 10-01, Volume: 315, Issue:4

    Topics: Acetyl Coenzyme A; Acetylation; Animals; Aspartate Aminotransferase, Mitochondrial; Aspartic Acid; Carbon Isotopes; Fatty Acids; Glycolysis; Inflammation; Lactic Acid; Lipopolysaccharides; Liver; Malate Dehydrogenase; Malates; Mitochondria, Liver; Oxidation-Reduction; Palmitic Acid; Pyruvic Acid; Stress, Physiological; Sus scrofa; Swine

2018
Liquid Chromatography-Tandem Mass Spectrometry Method Revealed that Lung Cancer Cells Exhibited Distinct Metabolite Profiles upon the Treatment with Different Pyruvate Dehydrogenase Kinase Inhibitors.
    Journal of proteome research, 2018, 09-07, Volume: 17, Issue:9

    Topics: A549 Cells; Acetyl Coenzyme A; Anilides; Antineoplastic Agents; Chromatography, Liquid; Citric Acid Cycle; Cytosol; Dichloroacetic Acid; Gene Expression Regulation; Glucose; Glycolysis; Humans; Isoenzymes; Lactic Acid; Mitochondria; Oxidative Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvic Acid; Tandem Mass Spectrometry

2018
Enhancing 3-hydroxypropionic acid production in combination with sugar supply engineering by cell surface-display and metabolic engineering of Schizosaccharomyces pombe.
    Microbial cell factories, 2018, Nov-13, Volume: 17, Issue:1

    Topics: Acetyl Coenzyme A; Batch Cell Culture Techniques; Carbon; Lactic Acid; Malonyl Coenzyme A; Metabolic Engineering; Metabolic Networks and Pathways; Oxidoreductases; Schizosaccharomyces; Sugars

2018
Dichloroacetate is an antimetabolite that antagonizes acetate and deprives cancer cells from its benefits: A novel evidence-based medical hypothesis.
    Medical hypotheses, 2019, Volume: 122

    Topics: Acetates; Acetyl Coenzyme A; Animals; Antineoplastic Agents; Brain Neoplasms; Chlorides; Dichloroacetic Acid; Evidence-Based Medicine; Glioblastoma; Heart; Humans; Ketones; Lactic Acid; Models, Theoretical; Neoplasms; Oxygen; Perfusion; Rats

2019
Coordinative metabolism of glutamine carbon and nitrogen in proliferating cancer cells under hypoxia.
    Nature communications, 2019, 01-14, Volume: 10, Issue:1

    Topics: Acetyl Coenzyme A; Ammonia; Animals; Carbon; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Female; Glucose; Glutamine; HEK293 Cells; Humans; Lactic Acid; Lipogenesis; Metabolic Networks and Pathways; Metabolome; Metabolomics; Mice; Mice, Nude; Neoplasms; Nitrogen; Nucleotides; Orotic Acid; Tumor Microenvironment; Xenograft Model Antitumor Assays

2019
Screening, expression, purification and characterization of CoA-transferases for lactoyl-CoA generation.
    Journal of industrial microbiology & biotechnology, 2019, Volume: 46, Issue:7

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Clostridium; Coenzyme A-Transferases; Lactic Acid

2019
Glis1 facilitates induction of pluripotency via an epigenome-metabolome-epigenome signalling cascade.
    Nature metabolism, 2020, Volume: 2, Issue:9

    Topics: Acetyl Coenzyme A; Animals; Cellular Reprogramming; Cellular Senescence; Chromatin Immunoprecipitation; DNA-Binding Proteins; Epigenome; Glucose; Induced Pluripotent Stem Cells; Lactic Acid; Male; Metabolome; Mice; Plasmids; Signal Transduction; Transcription Factors

2020
Dichloroacetate-induced metabolic reprogramming improves lifespan in a Drosophila model of surviving sepsis.
    PloS one, 2020, Volume: 15, Issue:11

    Topics: Acetyl Coenzyme A; Animals; Citric Acid Cycle; Dichloroacetic Acid; Drosophila melanogaster; Glycolysis; Inflammation; Lactic Acid; Longevity; Oxidative Phosphorylation; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Sepsis

2020
Unveiling the bioelectrocatalyzing behaviors and microbial ecological mechanisms behind caproate production without exogenous electron donor.
    Environmental research, 2022, Volume: 215, Issue:Pt 3

    Topics: Acetates; Acetyl Coenzyme A; Butyrates; Caproates; Carbon; Electrons; Ethanol; Fatty Acids; Fermentation; Hydrogen; Lactic Acid; Nitrates

2022
Enhancing 3-hydroxypropionic acid production in Saccharomyces cerevisiae through enzyme localization within mitochondria.
    Biochemical and biophysical research communications, 2023, 11-05, Volume: 680

    Topics: Acetyl Coenzyme A; Lactic Acid; Metabolic Engineering; Oxidoreductases; Saccharomyces cerevisiae

2023