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acetyl coenzyme a and cysteine

acetyl coenzyme a has been researched along with cysteine in 46 studies

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-199017 (36.96)18.7374
1990's6 (13.04)18.2507
2000's11 (23.91)29.6817
2010's8 (17.39)24.3611
2020's4 (8.70)2.80

Authors

AuthorsStudies
Burnell, JN; Whatley, FR1
Elce, JS; Green, RM1
Kresze, GB; Lynen, F; Oesterhelt, D; Steber, L1
Mucchielli, A; Saint-Lebe, L1
Nohmi, T; Sofuni, T; Watanabe, M1
Commandeur, JN; De Kanter, FJ; Vermeulen, NP1
Bloxham, DP; Salam, WH1
Frank, R; Knappe, J; Plaga, W1
Knudsen, J; Mikkelsen, J; Smith, S; Stern, A1
Barker, HA; Jeng, IM; Somack, R1
Londensborough, JC; Webster, LT; Yuan, SL1
Roskoski, R1
Ngo, TT; Shargool, PD1
Hsu, RY; Tian, WX; Wang, YS1
Katiyar, SS; Pan, D; Porter, JW1
Gozhansky, S; Nitzan, Y1
Kumar, S; Varagiannis, E1
Akagi, JM; Amelunxen, R; Gevertz, D1
Boulton, DA; Butkiewicz, EA; Cueto, MA; Hermes, JD; Lachance, PA; Rokosz, LL; Sanyal, G1
Kumar, GK; Shanmugasundaram, T; Sundaresh, CS1
Kurosaki, F1
Brown, A; Guest, JR; Jordan, F; Nemeria, N; Volkov, A; Yi, J; Zipper, L1
Child, CJ; Shoolingin-Jordan, PM1
Craft, CM; Zhan-Poe, X1
Modis, Y; Wierenga, RK1
Roediger, WE1
Anstrom, DM; Kallio, K; Remington, SJ1
Hindson, VJ1
Kelleher, NL; McLoughlin, SM; Tseng, CC; Walsh, CT1
Attwood, PV; Branson, JP; Jitrapakdee, S; Nezic, M; Wallace, JC1
Gleason, KJ; Hanna, PE; Vath, GM; Wagner, CR; Wang, H1
Cook, PF; Johnson, CM; Roderick, SL1
Fahey, RC; Newton, GL; Ta, P1
Kinoshita, K; Oshima, T; Shida, Y; Shimizu, M; Yamagishi, A1
Courtoy, PJ; Opperdoes, FR; Stroobant, V; Tyteca, D; Van Schaftingen, E; Veiga-da-Cunha, M1
Bai, H; Fan, K; Feng, D; Luo, Y; Peng, Y; Wang, H; Xiang, S; Yang, K; Yang, X; Yin, H; Yu, T; Zheng, J1
Fushinobu, S; Wakagi, T; Yan, Z1
Bavan, T; Berthoud, H; Bogicevic, B; Irmler, S; Meile, L; Portmann, R1
Blankenfeldt, W; Bock, T; Kasten, J; Müller, R1
Ithayaraja, M; Janardan, N; Murthy, MR; Savithri, HS; Wierenga, RK1
Ding, S; Fearnley, IM; Hall, AR; Hoogewijs, K; James, AM; Logan, A; Murphy, MP1
Chordia, MD; Chruszcz, M; Cooper, DR; Grabowski, M; Hou, J; Kwon, K; Minor, W; Tzou, WS; Zheng, H1
Hicks, JL; Oldham, KEA; Prentice, EJ; Summers, EL1
Asara, JM; Dambowsky, M; Dibble, CC; Jouandin, P; Marelja, Z; Nemazanyy, I; Parkhitko, AA; Perrimon, N; Shih, YH; Simons, M1
Asara, JM; Barritt, SA; Bartee, D; Cantley, LC; Clohessy, JG; Cohen, EB; Dibble, CC; DuBois-Coyne, SE; Geck, RC; Hopkins, BD; Lien, EC; Meier, JL; Perry, GE; Toker, A; Yuan, M; Zengeya, TT1
Bai, X; He, S; Xu, Y1

Reviews

1 review(s) available for acetyl coenzyme a and cysteine

ArticleYear
The serine acetyltransferase reaction: acetyl transfer from an acylpantothenyl donor to an alcohol.
    Archives of biochemistry and biophysics, 2005, Jan-01, Volume: 433, Issue:1

    Topics: Acetyl Coenzyme A; Acetylation; Acetyltransferases; Alcohols; Binding Sites; Catalysis; Cysteine; Enzyme Stability; Feedback, Physiological; Histidine; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Models, Structural; Molecular Structure; Molecular Weight; Protein Binding; Protein Conformation; Protein Structure, Quaternary; Protein Structure, Secondary; Serine; Serine O-Acetyltransferase; Substrate Specificity

2005

Other Studies

45 other study(ies) available for acetyl coenzyme a and cysteine

ArticleYear
Sulphur metabolism in Paracoccus denitrificans. Purification, properties and regulation of serine transacetylase, O-acetylserine sulphydrylase and beta-cystathionase.
    Biochimica et biophysica acta, 1977, Mar-15, Volume: 481, Issue:1

    Topics: Acetyl Coenzyme A; Acetyltransferases; Cystathionine gamma-Lyase; Cysteine; Cysteine Synthase; Hydrogen-Ion Concentration; Lyases; Paracoccus denitrificans; Selenium; Serine; Sulfhydryl Reagents

1977
Acetylation of S-substituted cysteines by a rat liver and kidney microsomal N-acetyltransferase.
    The Biochemical journal, 1975, Volume: 147, Issue:2

    Topics: Acetyl Coenzyme A; Acetyltransferases; Animals; Cysteine; Edetic Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney; Kinetics; Male; Microsomes; Microsomes, Liver; Rats; Sulfhydryl Reagents

1975
Reaction of yeast fatty acid synthetase with iodoacetamide. 2. Identification of the amino acid residues reacting with iodoacetamide and primary structure of a peptide containing the peripheral sulfhydryl group.
    European journal of biochemistry, 1977, Sep-15, Volume: 79, Issue:1

    Topics: Acetyl Coenzyme A; Amino Acid Sequence; Cysteine; Fatty Acid Synthases; Iodoacetamide; Iodoacetates; Pepsin A; Peptide Fragments; Saccharomyces cerevisiae; Trypsin

1977
[The mechanism is action of hydrogen peroxide on bacterial metabolism].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1976, Sep-13, Volume: 283, Issue:4

    Topics: Acetyl Coenzyme A; Cysteine; Escherichia coli; Glutathione; Hydrogen Peroxide; Ketoglutaric Acids; Pyruvates; Thioctic Acid

1976
Involvement of Cys69 residue in the catalytic mechanism of N-hydroxyarylamine O-acetyltransferase of Salmonella typhimurium. Sequence similarity at the amino acid level suggests a common catalytic mechanism of acetyltransferase for S. typhimurium and high
    The Journal of biological chemistry, 1992, Apr-25, Volume: 267, Issue:12

    Topics: Acetyl Coenzyme A; Acetyltransferases; Acyltransferases; Amino Acid Sequence; Catalysis; Cysteine; DNA, Bacterial; Electrophoresis, Polyacrylamide Gel; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Restriction Mapping; Salmonella typhimurium; Sequence Homology, Nucleic Acid

1992
Bioactivation of the cysteine-S-conjugate and mercapturic acid of tetrafluoroethylene to acylating reactive intermediates in the rat: dependence of activation and deactivation activities on acetyl coenzyme A availability.
    Molecular pharmacology, 1989, Volume: 36, Issue:4

    Topics: Acetyl Coenzyme A; Acetylcysteine; Acylation; Animals; Biotransformation; Carbon-Sulfur Lyases; Cysteine; Fluorocarbons; Gas Chromatography-Mass Spectrometry; Kidney; Liver; Lyases; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Inbred Strains; Subcellular Fractions; Time Factors

1989
Identification of subsidiary catalytic groups at the active site of beta-ketoacyl-CoA thiolase by covalent modification of the protein.
    Biochimica et biophysica acta, 1986, Oct-17, Volume: 873, Issue:3

    Topics: Acetyl Coenzyme A; Acetyl-CoA C-Acetyltransferase; Acetyltransferases; Acyl Coenzyme A; Amines; Anhydrides; Animals; Binding Sites; Catalysis; Cysteine; Cytosol; Hydrogen-Ion Concentration; Liver; Methyl Methanesulfonate; Rats; Sulfhydryl Compounds; Swine

1986
Catalytic-site mapping of pyruvate formate lyase. Hypophosphite reaction on the acetyl-enzyme intermediate affords carbon-phosphorus bond synthesis (1-hydroxyethylphosphonate).
    European journal of biochemistry, 1988, Dec-15, Volume: 178, Issue:2

    Topics: Acetyl Coenzyme A; Acetylation; Acetyltransferases; Amino Acid Sequence; Binding Sites; Catalysis; Cysteine; Energy Transfer; Escherichia coli; Formates; Hydrolysis; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Pyruvates

1988
Stoichiometry of substrate binding to rat liver fatty acid synthetase.
    The Biochemical journal, 1985, Sep-01, Volume: 230, Issue:2

    Topics: Acetates; Acetic Acid; Acetyl Coenzyme A; Animals; Binding Sites; Cysteamine; Cysteine; Fatty Acid Synthases; Iodoacetamide; Liver; Malonates; Malonyl Coenzyme A; Pantetheine; Rats

1985
Ornithine degradation in Clostridium sticklandii; pyridoxal phosphate and coenzyme A dependent thiolytic cleavage of 2-amino-4-ketopentanoate to alanine and acetyl coenzyme A.
    Biochemistry, 1974, Jul-02, Volume: 13, Issue:14

    Topics: Acetyl Coenzyme A; Alanine; Amino Acids; Apoproteins; Carbon Radioisotopes; Catalysis; Chromatography, Paper; Clostridium; Coenzyme A; Cysteine; Electrophoresis, Paper; Enzyme Activation; Keto Acids; Ornithine; Pyridoxal Phosphate; Species Specificity; Structure-Activity Relationship; Sulfhydryl Reagents; Thiolester Hydrolases; Valerates

1974
The molecular weight and thiol residues of acetyl-coenzyme A synthetase from ox heart mitochondria.
    The Biochemical journal, 1973, Volume: 133, Issue:1

    Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Amino Acids; Animals; Binding Sites; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Coenzyme A Ligases; Cysteine; Electrophoresis, Disc; Hydrogen-Ion Concentration; Hydroxymercuribenzoates; Kinetics; Mitochondria, Muscle; Molecular Weight; Myocardium; Protein Binding; Protein Conformation; Spectrophotometry; Spectrophotometry, Ultraviolet; Time Factors; Ultracentrifugation

1973
Choline acetyltransferase. Evidence for an acetyl-enzyme reaction intermediate.
    Biochemistry, 1973, Sep-11, Volume: 12, Issue:19

    Topics: Acetyl Coenzyme A; Acetylcholine; Acetyltransferases; Animals; Binding Sites; Brain; Carbon Isotopes; Carnitine; Catalysis; Cattle; Choline; Chromatography, Gel; Coenzyme A; Cysteine; Drug Stability; Esters; Guanidines; Hydrogen-Ion Concentration; Organophosphorus Compounds; Pantothenic Acid; Sulfhydryl Compounds; Sulfides; Trichloroacetic Acid; Tritium

1973
The enzymatic synthesis of L-cysteine in higher plant tissues.
    Canadian journal of biochemistry, 1974, Volume: 52, Issue:6

    Topics: Acetyl Coenzyme A; Acetyltransferases; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Drug Stability; Hydrogen-Ion Concentration; Kinetics; Lyases; Plants; Serine; Species Specificity; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Sulfur Radioisotopes; Time Factors

1974
Hybridization studies of chicken liver fatty acid synthetase. Evidence for the participation in palmitate synthesis of cysteine and phosphopantetheine sulfhydryl groups on adjacent subunits.
    The Journal of biological chemistry, 1984, Nov-25, Volume: 259, Issue:22

    Topics: Acetyl Coenzyme A; Animals; Chickens; Cysteine; Fatty Acid Synthases; Iodoacetamide; Liver; Palmitates; Palmitic Acids; Sulfhydryl Compounds; Time Factors

1984
Inactivation of 3-oxoacyl synthetase activity of pigeon liver fatty acid synthetase by S-(4-bromo-2,3-dioxobutyl)-coenzyme A.
    European journal of biochemistry, 1983, Jan-17, Volume: 130, Issue:1

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Acetyl Coenzyme A; Acetyltransferases; Acyl-Carrier Protein S-Acetyltransferase; Acyltransferases; Amino Acids; Animals; Coenzyme A; Columbidae; Cysteine; Enzyme Activation; Fatty Acid Synthases; Iodoacetamide; Kinetics; Liver; Malonyl Coenzyme A; Pantetheine; Spectrophotometry

1983
Chloramphenicol binding site of an fi- R-factor-specified variant of chloramphenicol acetyltransferase.
    Archives of biochemistry and biophysics, 1980, Apr-15, Volume: 201, Issue:1

    Topics: Acetyl Coenzyme A; Acetyltransferases; Binding Sites; Chloramphenicol; Chloramphenicol O-Acetyltransferase; Cysteine; Escherichia coli; Kinetics; R Factors; Sulfhydryl Reagents

1980
Chicken liver fatty acid synthetase dimer: evidence of asymmetrical structure from iodoacetamide inhibition studies.
    Bioscience reports, 1982, Volume: 2, Issue:3

    Topics: Acetyl Coenzyme A; Animals; Chickens; Cysteine; Fatty Acid Synthases; Iodoacetamide; Iodoacetates; Kinetics; Liver; Macromolecular Substances; Pantetheine; Protein Conformation

1982
Cysteine synthesis by Desulfovibrio vulgaris extracts.
    Journal of bacteriology, 1980, Volume: 141, Issue:3

    Topics: Acetyl Coenzyme A; Acetyltransferases; Cysteine; Cysteine Synthase; Desulfovibrio; Pyruvates; Serine O-Acetyltransferase; Sulfites

1980
Human cytoplasmic 3-hydroxy-3-methylglutaryl coenzyme A synthase: expression, purification, and characterization of recombinant wild-type and Cys129 mutant enzymes.
    Archives of biochemistry and biophysics, 1994, Volume: 312, Issue:1

    Topics: Acetyl Coenzyme A; Amino Acid Sequence; Base Sequence; Cloning, Molecular; Cysteine; Escherichia coli; Fatty Acids, Unsaturated; Fluorescent Dyes; Gene Library; Humans; Hydroxymethylglutaryl-CoA Synthase; Lactones; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Recombinant Proteins; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Structure-Activity Relationship

1994
Identification of a cysteine involved in the interaction between carbon monoxide dehydrogenase and corrinoid/Fe-S protein from Clostridium thermoaceticum.
    FEBS letters, 1993, Jul-12, Volume: 326, Issue:1-3

    Topics: Acetyl Coenzyme A; Aldehyde Oxidoreductases; Amino Acid Sequence; Binding Sites; Catalysis; Chromatography, High Pressure Liquid; Clostridium; Corrinoids; Cysteine; Disulfides; Dithioerythritol; Iron-Sulfur Proteins; Molecular Sequence Data; Multienzyme Complexes; Vitamin B 12

1993
Transacylase-like structure and its role in substrate channeling of 6-hydroxymellein synthase, a multifunctional polyketide biosynthetic enzyme in carrot cell extracts.
    FEBS letters, 1996, Jan-22, Volume: 379, Issue:1

    Topics: Acetyl Coenzyme A; Acyl Carrier Protein; Acyltransferases; Binding Sites; Cysteine; Daucus carota; Ligases; Malonyl Coenzyme A; Molecular Structure; Multienzyme Complexes; Oxidoreductases; Substrate Specificity; Sulfhydryl Compounds; Sulfhydryl Reagents; Sulfones

1996
Systematic study of the six cysteines of the E1 subunit of the pyruvate dehydrogenase multienzyme complex from Escherichia coli: none is essential for activity.
    Biochemistry, 1998, Jan-20, Volume: 37, Issue:3

    Topics: Acetyl Coenzyme A; Binding, Competitive; Cysteine; Dimerization; Enzyme Activation; Escherichia coli; Fatty Acids, Unsaturated; Feedback; Genetic Variation; Kinetics; Mutagenesis, Site-Directed; Plasmids; Pyruvate Dehydrogenase Complex; Pyruvates; Thiamine Pyrophosphate

1998
Inactivation of the polyketide synthase, 6-methylsalicylic acid synthase, by the specific modification of Cys-204 of the beta-ketoacyl synthase by the fungal mycotoxin cerulenin.
    The Biochemical journal, 1998, Mar-01, Volume: 330 ( Pt 2)

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Acetyl Coenzyme A; Acyltransferases; Alkylation; Antifungal Agents; Binding, Competitive; Cerulenin; Cyanogen Bromide; Cysteine; Iodoacetamide; Kinetics; Ligases; Malonyl Coenzyme A; Models, Chemical; Multienzyme Complexes; Oxidoreductases; Penicillium; Peptide Mapping; Serine Endopeptidases; Staphylococcus aureus

1998
Identification of specific histidine residues and the carboxyl terminus are essential for serotonin N-acetyltransferase enzymatic activity.
    Brain research. Molecular brain research, 2000, Feb-22, Volume: 75, Issue:2

    Topics: Acetyl Coenzyme A; Amino Acid Sequence; Animals; Arylamine N-Acetyltransferase; Conserved Sequence; Cysteine; Enzyme Stability; Gene Deletion; Histidine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Rats; Sequence Homology, Amino Acid

2000
Crystallographic analysis of the reaction pathway of Zoogloea ramigera biosynthetic thiolase.
    Journal of molecular biology, 2000, Apr-14, Volume: 297, Issue:5

    Topics: Acetyl Coenzyme A; Acetyl-CoA C-Acetyltransferase; Acetylation; Amino Acid Sequence; Binding Sites; Catalysis; Catalytic Domain; Coenzyme A; Crystallography, X-Ray; Cysteine; Freezing; Hydrogen Bonding; Ligands; Models, Molecular; Molecular Sequence Data; Nitrogen; Oxygen; Protein Binding; Protein Structure, Secondary; Saccharomyces cerevisiae; Static Electricity; Structure-Activity Relationship; Zoogloea

2000
Nitric oxide-dependent nitrosation of cellular CoA: a proposal for tissue responses.
    Nitric oxide : biology and chemistry, 2001, Volume: 5, Issue:2

    Topics: Acetyl Coenzyme A; Acetylation; Apoptosis; Coenzyme A; Colitis; Cysteine; Glutathione; Humans; Nitric Oxide; Nitrosation; Nitroso Compounds; S-Nitrosoglutathione

2001
Structure of the Escherichia coli malate synthase G:pyruvate:acetyl-coenzyme A abortive ternary complex at 1.95 A resolution.
    Protein science : a publication of the Protein Society, 2003, Volume: 12, Issue:9

    Topics: Acetyl Coenzyme A; Arginine; Aspartic Acid; Binding Sites; Candida albicans; Crystallography, X-Ray; Cysteine; Escherichia coli; Kinetics; Malate Synthase; Models, Chemical; Models, Molecular; Mutagenesis; Mycobacterium tuberculosis; Oxidation-Reduction; Protein Binding; Protein Conformation; Protein Isoforms; Pyruvic Acid; Sulfenic Acids; X-Rays

2003
Serine acetyltransferase of Escherichia coli: substrate specificity and feedback control by cysteine.
    The Biochemical journal, 2003, Nov-01, Volume: 375, Issue:Pt 3

    Topics: Acetyl Coenzyme A; Acetyltransferases; Acyl Coenzyme A; Adenosine Triphosphate; Calorimetry; Cysteine; Escherichia coli; Feedback, Physiological; Glycine; Kinetics; Serine; Serine O-Acetyltransferase; Substrate Specificity; Threonine

2003
Role of the active site cysteine of DpgA, a bacterial type III polyketide synthase.
    Biochemistry, 2004, Feb-03, Volume: 43, Issue:4

    Topics: Acetyl Coenzyme A; Alanine; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Carbon Radioisotopes; Catalysis; Coenzyme A Ligases; Cysteine; Decarboxylation; Kinetics; Malonyl Coenzyme A; Molecular Sequence Data; Mutagenesis, Site-Directed; Substrate Specificity

2004
Kinetic characterization of yeast pyruvate carboxylase isozyme Pyc1 and the Pyc1 mutant, C249A.
    Biochemistry, 2004, Feb-03, Volume: 43, Issue:4

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Adenosine Diphosphate; Alanine; Amino Acid Sequence; Bicarbonates; Carbamyl Phosphate; Carbon-Nitrogen Ligases; Catalysis; Cysteine; Deuterium Exchange Measurement; Escherichia coli Proteins; Isoenzymes; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; o-Phthalaldehyde; Phosphorylation; Pyruvate Carboxylase; Saccharomyces cerevisiae Proteins; Solvents

2004
Probing the mechanism of hamster arylamine N-acetyltransferase 2 acetylation by active site modification, site-directed mutagenesis, and pre-steady state and steady state kinetic studies.
    Biochemistry, 2004, Jun-29, Volume: 43, Issue:25

    Topics: Acetamides; Acetyl Coenzyme A; Acetylation; Alkylating Agents; Amino Acid Sequence; Amino Acid Substitution; Animals; Arylamine N-Acetyltransferase; Binding Sites; Cricetinae; Cysteine; Deuterium; Enzyme Inhibitors; Hydrogen-Ion Concentration; Iodoacetamide; Isoenzymes; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Nitrophenols; Papain; Protein Conformation; Recombinant Proteins

2004
A mycothiol synthase mutant of Mycobacterium smegmatis produces novel thiols and has an altered thiol redox status.
    Journal of bacteriology, 2005, Volume: 187, Issue:21

    Topics: Acetyl Coenzyme A; Acetyltransferases; Acyl Coenzyme A; Benzene Derivatives; Cysteine; Disaccharides; DNA Transposable Elements; Glycopeptides; Hydrogen Peroxide; Inositol; Mutagenesis, Insertional; Mycobacterium smegmatis; Oxidants; Oxidation-Reduction; Pyrazoles; Sulfhydryl Compounds; tert-Butylhydroperoxide

2005
Prebiotic origin of glycolytic metabolism: histidine and cysteine can produce acetyl CoA from glucose via reactions homologous to non-phosphorylated Entner-Doudoroff pathway.
    Journal of biochemistry, 2008, Volume: 144, Issue:3

    Topics: Acetyl Coenzyme A; Amino Acids; Biochemistry; Catalysis; Chromatography, Thin Layer; Cysteine; Gluconates; Glucose; Glycolysis; Histidine; Mass Spectrometry; Models, Biological; NAD; Phosphorylation; Time Factors

2008
Molecular identification of NAT8 as the enzyme that acetylates cysteine S-conjugates to mercapturic acids.
    The Journal of biological chemistry, 2010, Jun-11, Volume: 285, Issue:24

    Topics: Acetyl Coenzyme A; Acetylation; Acetylcysteine; Acetyltransferases; Cell Line; Codon, Terminator; Cysteine; Cytosol; Endoplasmic Reticulum; Humans; Microscopy, Confocal; Mutation; Polymorphism, Single Nucleotide; Xenobiotics

2010
Induction of holomycin production and complex metabolic changes by the argR mutation in Streptomyces clavuligerus NP1.
    Applied and environmental microbiology, 2012, Volume: 78, Issue:9

    Topics: Acetyl Coenzyme A; Bacterial Proteins; Clavulanic Acid; Cysteine; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Gene Knockout Techniques; Lactams; Proteome; Repressor Proteins; Streptomyces

2012
Four Cys residues in heterodimeric 2-oxoacid:ferredoxin oxidoreductase are required for CoA-dependent oxidative decarboxylation but not for a non-oxidative decarboxylation.
    Biochimica et biophysica acta, 2014, Volume: 1844, Issue:4

    Topics: Acetyl Coenzyme A; Alanine; Archaeal Proteins; Cysteine; Decarboxylation; Escherichia coli; Free Radicals; Iron; Iron-Sulfur Proteins; Ketone Oxidoreductases; Mutagenesis, Site-Directed; Oxidation-Reduction; Protein Multimerization; Recombinant Proteins; Sulfolobus; Sulfur

2014
Cysteine biosynthesis in Lactobacillus casei: identification and characterization of a serine acetyltransferase.
    FEMS microbiology letters, 2016, Volume: 363, Issue:4

    Topics: Acetyl Coenzyme A; Cloning, Molecular; Culture Media; Cysteine; Cysteine Synthase; DNA, Bacterial; Escherichia coli; Lacticaseibacillus casei; Molecular Sequence Annotation; Mutation; Plasmids; Recombinant Proteins; Serine; Serine O-Acetyltransferase; Sulfur

2016
Crystal Structure of the HMG-CoA Synthase MvaS from the Gram-Negative Bacterium Myxococcus xanthus.
    Chembiochem : a European journal of chemical biology, 2016, 07-01, Volume: 17, Issue:13

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Catalysis; Catalytic Domain; Crystallography, X-Ray; Cysteine; Humans; Hydrogen Bonding; Hydroxymethylglutaryl-CoA Synthase; Models, Chemical; Mustard Plant; Myxococcus xanthus; Protein Multimerization; Staphylococcus aureus

2016
Crystal structure of a thiolase from Escherichia coli at 1.8 Å resolution.
    Acta crystallographica. Section F, Structural biology communications, 2016, Volume: 72, Issue:Pt 7

    Topics: Acetyl Coenzyme A; Acetyl-CoA C-Acetyltransferase; Amino Acid Motifs; Catalytic Domain; Cloning, Molecular; Crystallography, X-Ray; Cysteine; Escherichia coli; Escherichia coli Proteins; Gene Expression; Kinetics; Lysine; Models, Molecular; Plasmids; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Multimerization; Recombinant Proteins; Substrate Specificity; Water

2016
Non-enzymatic N-acetylation of Lysine Residues by AcetylCoA Often Occurs via a Proximal S-acetylated Thiol Intermediate Sensitive to Glyoxalase II.
    Cell reports, 2017, 02-28, Volume: 18, Issue:9

    Topics: Acetyl Coenzyme A; Acetylation; Cysteine; Fatty Acid Synthases; Humans; Lysine; Mitochondria; Mitochondrial Proteins; Recombinant Proteins; Sirtuin 3; Sulfhydryl Compounds; Thiolester Hydrolases

2017
Differences in substrate specificity of V. cholerae FabH enzymes suggest new approaches for the development of novel antibiotics and biofuels.
    The FEBS journal, 2018, Volume: 285, Issue:15

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Acetyl Coenzyme A; Acyl Coenzyme A; Anti-Bacterial Agents; Bacterial Proteins; Binding Sites; Biofuels; Crystallography, X-Ray; Cysteine; Models, Molecular; Protein Conformation; Protein Multimerization; Structure-Activity Relationship; Substrate Specificity; Vibrio cholerae

2018
Serine acetyltransferase from Neisseria gonorrhoeae; structural and biochemical basis of inhibition.
    The Biochemical journal, 2022, 01-14, Volume: 479, Issue:1

    Topics: Acetyl Coenzyme A; Amino Acid Sequence; Biocatalysis; Catalytic Domain; Cloning, Molecular; Crystallization; Crystallography, X-Ray; Cysteine; Escherichia coli; Feedback, Physiological; Kinetics; Ligands; Malates; Neisseria gonorrhoeae; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Serine; Serine O-Acetyltransferase

2022
Lysosomal cystine mobilization shapes the response of TORC1 and tissue growth to fasting.
    Science (New York, N.Y.), 2022, 02-18, Volume: 375, Issue:6582

    Topics: Acetyl Coenzyme A; Amino Acid Transport Systems, Neutral; Amino Acids; Animals; Autophagy; Citric Acid Cycle; Cysteine; Cystine; Cytosol; Diet, Protein-Restricted; Drosophila melanogaster; Drosophila Proteins; Fasting; Fat Body; Lysosomes; Mechanistic Target of Rapamycin Complex 1; Models, Animal; Signal Transduction; Transcription Factors

2022
PI3K drives the de novo synthesis of coenzyme A from vitamin B5.
    Nature, 2022, Volume: 608, Issue:7921

    Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Cell Proliferation; Coenzyme A; Cysteine; Lipid Metabolism; Mass Spectrometry; Metabolomics; Pantothenic Acid; Phosphatidylinositol 3-Kinase; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Proto-Oncogene Proteins c-akt; Signal Transduction

2022
Structural insight into the role of thiolase from Fusobacterium nucleatum.
    Biochemical and biophysical research communications, 2023, Dec-25, Volume: 688

    Topics: Acetyl Coenzyme A; Acetyl-CoA C-Acetyltransferase; Cysteine; Fatty Acids; Fusobacterium nucleatum

2023