Compounds > acetyl coenzyme a
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acetyl coenzyme a and citric acid, anhydrous

acetyl coenzyme a has been researched along with citric acid, anhydrous in 74 studies

Research

Studies (74)

TimeframeStudies, this research(%)All Research%
pre-199017 (22.97)18.7374
1990's7 (9.46)18.2507
2000's16 (21.62)29.6817
2010's24 (32.43)24.3611
2020's10 (13.51)2.80

Authors

AuthorsStudies
Chicco, A; Gutman, R; Lombardo, YB1
Brunengraber, H; David, F; Des Rosiers, C; Garneau, M1
Cronholm, T; Norsten, C1
Costello, LC; Franklin, RB3
Akuffo, V; Costello, LC; Franklin, RB; Kahng, MW1
Akuffo, V; Costello, LC; Franklin, RB1
Kubicek, CP; Pfitzner, A; Röhr, M1
Pande, SV1
Bibinger, A; Eggerer, H; Lill, U1
Agius, L; Vaartjes, WJ1
Bar-Tana, J; Rose-Kahn, G1
Ahmad, F; Ahmad, PM; Barden, RE; Gupta, S1
Lane, MD; Mooney, RA1
Rícný, J; Tucek, S1
Greksák, M; Lopes-Cardozo, M; van den Bergh, SG1
Bielarczyk, H; Kabata, J; Szutowicz, A1
Besson, C; Demigne, C; Morand, C; Remesy, C1
Dyck, DJ; Peters, SJ; Spriet, LL; Wendling, PS1
Bielarczyk, H; Szutowicz, A; Tomaszewicz, M1
Drysdale, GR; Hsu, F; Kurz, LC; Nakra, T; Plungkhen, W; Riley, M; Stein, R1
Christensen, B; Nielsen, J1
Panneman, H; Ruijter, GJ; Visser, J; Xu, D1
Chen, J; Danson, MJ; Drysdale, G; Kurz, LC; Riley, M; Russell, RJ; Tomar, MA1
Comte, B; Poirier, M; Rosiers, CD; Vincent, G1
Friars, D; Graham, TE; Greer, F1
Delhaize, E; Ma, JF; Ryan, PR1
Bouchard, B; Brunengraber, H; Des Rosiers, C; Kelleher, JK; Poirier, M; Reszko, AE; Vincent, G1
LYNEN, F; OCHOA, S; STERN, JR1
DATTA, SP; TATE, SS1
JOSHI, AP; PATEL, NT; RAINA, PN; RAMAKRISHNAN, CV1
Adams, JE; Bian, F; Brunengraber, H; David, F; Hoppel, CL; Jobbins, KA; Kasumov, T; Minkler, PE; Thomas, KR1
De Gelder, J; De Gussem, K; De Vos, P; Moens, L; Vandenabeele, P1
Eisenreich, W; Fuchs, G; Huber, H; Hügler, M; Jahn, U1
Battram, DS; Dela, F; El-Sohemy, A; Graham, TE; Thong, FS1
Newgard, CB; Rathmell, JC1
Bui, TV; Cross, JR; Hatzivassiliou, G; Sachdeva, UM; Thompson, CB; Wellen, KE1
Allmann, S; Biran, M; Boshart, M; Bringaud, F; Franconi, JM; Hahn, M; Moreau, P; Plazolles, N; Rivière, L1
Geelen, MJ; Gnoni, GV; Priore, P; Siculella, L1
Bielarczyk, H; Jankowska-Kulawy, A; Pawełczyk, T; Szutowicz, A; Wróblewska, M1
Chandel, NS; Chen, PH; Cheng, T; DeBerardinis, RJ; Jin, ES; Linehan, WM; Mullen, AR; Sullivan, LB; Wheaton, WW; Yang, Y1
Atherton, HJ; Clarke, K; Cochlin, LE; Dodd, MS; Lee, P; Radda, GK; Schroeder, MA; Tyler, DJ1
Caza, M; De Repentigny, L; Fries, B; Gates-Hollingsworth, MA; Griffiths, EJ; Gsponer, J; Hu, G; Kozel, TR; Kronstad, JW; Wang, J1
Fassio, SR; Häse, CC; Minato, Y; Wolfe, AJ1
Chen, H; Geng, H; He, X; Liu, H1
Damiano, F; Gnoni, GV; Siculella, L; Tocci, R1
Calvaruso, MA; DeBerardinis, RJ; Hensley, CT; Jiang, L; Kim, J; Ko, B; Lumata, L; Merritt, ME; Mitsche, M; Rutter, J; Sudderth, J; Wasti, AT; Yang, C1
Kawamura, Y; Kosono, S; Nishiyama, M; Suzuki, S; Tamura, M; Yoshida, A; Yoshida, M1
Des Rosiers, C; Isern, NG; Kajimoto, M; Ledee, DR; Olson, AK; Portman, MA1
Bielarczyk, H; Gul-Hinc, S; Höfling, C; Jankowska-Kulawy, A; Pawelczyk, T; Ronowska, A; Roßner, S; Schliebs, R; Szutowicz, A1
Alves, TC; Cline, GW; Kibbey, RG; Mason, G; Pongratz, RL; Sereda, S; Shirihai, O; Yarborough, O; Zhao, X1
Baker, SE; Bredeweg, EL; Chu, RK; Hu, D; Kim, YM; Metz, TO; Nicora, CD; Pomraning, KR; Purvine, SO1
Chen, J; Esen, E; Hsu, FF; Karner, CM; Long, F; Turk, J1
Alper, HS; Cordova, LT1
Ansari, IH; Burant, CF; El Azzouny, M; Jitrapakdee, S; Longacre, MJ; MacDonald, MJ; Phannasil, P; Rattanapornsompong, K1
Lincet, H1
Chen, Y; Deb, DK; Li, YC; Sun, J; Wang, Y1
Bačnik, K; Berg, IA; Boll, M; Eisenreich, W; Huber, C; Hügler, M; Kowarschik, S; Mall, A; Mergelsberg, M; Sobotta, J; Tschirner, C1
Bilodeau, M; Cassim, S; Dehbidi-Assadzadeh, L; Lapierre, P; Raymond, VA1
Abriola, P; Bisaccia, F; Convertini, P; D'Angelo, S; Infantino, V; Leccese, P; Padula, A; Santarsiero, A1
Futagami, T; Goto, M; Izumitsu, K; Kadooka, C; Okutsu, K; Onoue, M; Takamine, K; Tamaki, H; Yoshizaki, Y1
Ito, S; Koyama, N; Osanai, T1
Chen, D; Duan, Y; Li, J; Li, M; Xu, C; Zhou, M; Zhou, Z1
Albanese, C; Avantaggiati, ML; Catalina-Rodriguez, O; Cheema, A; Foley, P; Gadre, S; Giaccone, G; Graham, GT; Kallakury, B; Kasprzyk-Pawelec, A; Mosaoa, R; Parasido, E; Tan, M; Yi, C1
Carrer, A; Fernandez, S; Gade, TP; Gilbert, M; Izzo, L; Jang, C; Liu, J; Miller, KD; Rabinowitz, JD; Schug, ZT; Snyder, NW; Titchenell, PM; Trefely, S; Uehara, K; Wellen, KE; Zeng, X; Zhao, S1
Cherono, S; Han, Y; Jiang, X; Liu, J; Ntini, C; Ogutu, C; Zhang, X; Zhao, L; Zheng, B1
Allen, MS; Donkin, SS; Kennedy, KM1
Eisenreich, W; Fischer, W; Goebel, W; Haas, R; Lettl, C; Schindele, F; Steiner, TM1
Denu, JM; Dieterich, IA; Frelka, A; Lawton, AJ; Li, L; Ma, M; Miles, HN; Orefice, NS; Pearce, RA; Puglielli, L; Rigby, MJ; Shapiro, SL; Yi, SY; Yu, JPJ1
Baron, DM; Bischoff, AT; Brenner, M; Büchner, B; Djinovic-Carugo, K; Dobretzberger, V; Fragner, L; Klopstock, T; Mlynek, G; Müllner, EW; Salzer, U; Weckwerth, W; Werning, M1
Fernandez-Fuente, G; Puglielli, L; Rigby, MJ1
Chhimpa, N; Kayath, HP; Puri, N; Singh, N1
Alexander, CM; Coon, JJ; Denu, JM; Fernandez-Fuente, G; Gallego-Muñoz, P; Kasza, I; Lawton, AJ; Overmyer, KA; Puglielli, L; Shapiro, SL1

Reviews

8 review(s) available for acetyl coenzyme a and citric acid, anhydrous

ArticleYear
Metabolic network analysis. A powerful tool in metabolic engineering.
    Advances in biochemical engineering/biotechnology, 2000, Volume: 66

    Topics: Acetyl Coenzyme A; Algorithms; Biomass; Biomedical Technology; Citric Acid; Citric Acid Cycle; Glucose-6-Phosphate; Isocitrates; Lysine; Mannitol; Metabolism; Models, Biological; Oxaloacetic Acid; Propionates; Pyruvic Acid; Saccharomyces cerevisiae

2000
The clinical relevance of the metabolism of prostate cancer; zinc and tumor suppression: connecting the dots.
    Molecular cancer, 2006, May-15, Volume: 5

    Topics: Acetyl Coenzyme A; Cation Transport Proteins; Citric Acid; Genes, Tumor Suppressor; Humans; Magnetic Resonance Spectroscopy; Male; Oxidation-Reduction; Prostate; Prostatic Neoplasms; Zinc

2006
Does caffeine alter muscle carbohydrate and fat metabolism during exercise?
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2008, Volume: 33, Issue:6

    Topics: Acetyl Coenzyme A; Adenosine Monophosphate; Biopsy; Caffeine; Carbohydrate Metabolism; Central Nervous System Stimulants; Citric Acid; Dietary Fats; Energy Metabolism; Exercise; Glucose-6-Phosphate; Glycogen; Humans; Muscle, Skeletal; Oxygen Consumption

2008
The mitochondrial citrate carrier: metabolic role and regulation of its activity and expression.
    IUBMB life, 2009, Volume: 61, Issue:10

    Topics: Acetyl Coenzyme A; Animals; Binding Sites; Carrier Proteins; Citric Acid; Cytosol; Fatty Acids; Fatty Acids, Unsaturated; Forecasting; Gene Expression Regulation; Kinetics; Lipogenesis; Liver; Membrane Transport Proteins; Mitochondria; Mitochondria, Liver; Promoter Regions, Genetic; Protein Binding; Rats

2009
Central metabolic nodes for diverse biochemical production.
    Current opinion in chemical biology, 2016, Volume: 35

    Topics: Acetyl Coenzyme A; Aspartic Acid; Bacteria; Citric Acid; Fungi; Pyruvic Acid; Tyrosine

2016
The reduced concentration of citrate in cancer cells: An indicator of cancer aggressiveness and a possible therapeutic target.
    Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy, 2016, Volume: 29

    Topics: Acetyl Coenzyme A; Apoptosis; ATP Citrate (pro-S)-Lyase; Biomarkers, Tumor; Citric Acid; Citric Acid Cycle; Epigenesis, Genetic; Glycolysis; Humans; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Invasiveness; Neoplasms; Oxidative Phosphorylation; Prognosis

2016
Intracellular Citrate/acetyl-CoA flux and endoplasmic reticulum acetylation: Connectivity is the answer.
    Molecular metabolism, 2023, Volume: 67

    Topics: Acetyl Coenzyme A; Acetylation; Animals; Citrates; Citric Acid; Endoplasmic Reticulum; Humans; Lysine; Mice; Protein Processing, Post-Translational

2023
The Novel Role of Mitochondrial Citrate Synthase and Citrate in the Pathophysiology of Alzheimer's Disease.
    Journal of Alzheimer's disease : JAD, 2023, Volume: 94, Issue:s1

    Topics: Acetyl Coenzyme A; Alzheimer Disease; Citrate (si)-Synthase; Citrates; Citric Acid; Glucose Transporter Type 3; Humans

2023

Trials

1 trial(s) available for acetyl coenzyme a and citric acid, anhydrous

ArticleYear
Comparison of caffeine and theophylline ingestion: exercise metabolism and endurance.
    Journal of applied physiology (Bethesda, Md. : 1985), 2000, Volume: 89, Issue:5

    Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Blood Glucose; Caffeine; Central Nervous System Stimulants; Citric Acid; Cyclic AMP; Energy Metabolism; Epinephrine; Fatty Acids, Nonesterified; Glucose-6-Phosphatase; Glycerol; Glycogen; Humans; Lactic Acid; Male; Muscle, Skeletal; Norepinephrine; Oxygen Consumption; Physical Endurance; Theophylline; Vasodilator Agents; Xanthines

2000

Other Studies

65 other study(ies) available for acetyl coenzyme a and citric acid, anhydrous

ArticleYear
Biochemical abnormalities in the heart of rats fed a sucrose-rich diet: is the low activity of the pyruvate dehydrogenase complex a result of increased fatty acid oxidation?
    Metabolism: clinical and experimental, 1991, Volume: 40, Issue:1

    Topics: Acetyl Coenzyme A; Animals; Citrates; Citric Acid; Dietary Carbohydrates; Epoxy Compounds; Fatty Acids; Glucose-6-Phosphate; Glucosephosphates; Heart; Hypoglycemic Agents; Lactates; Lactic Acid; Male; Myocardium; Nucleotides; Oxidation-Reduction; Papillary Muscles; Pyruvate Dehydrogenase Complex; Rats; Sucrose

1991
Nonhomogeneous labeling of liver mitochondrial acetyl-CoA.
    The Journal of biological chemistry, 1991, Jan-25, Volume: 266, Issue:3

    Topics: Acetates; Acetoacetates; Acetyl Coenzyme A; Animals; Caprylates; Citrates; Citric Acid; Ketone Bodies; Mitochondria, Liver; Pyruvates; Rats; Rats, Inbred Strains

1991
Compartmentation of acetyl CoA studied by analysis of tricarboxylic acid cycle acids and 3-hydroxybutyrate in bile of rats given [2,2,2-2H3]ethanol.
    The Biochemical journal, 1990, Jan-15, Volume: 265, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acetates; Acetyl Coenzyme A; Animals; Bile; Carbon Radioisotopes; Carboxylic Acids; Citrates; Citric Acid; Citric Acid Cycle; Deuterium; Ethanol; Female; Gas Chromatography-Mass Spectrometry; Hydroxybutyrates; Kinetics; Radioisotope Dilution Technique; Rats; Rats, Inbred Strains

1990
Prostate epithelial cells utilize glucose and aspartate as the carbon sources for net citrate production.
    The Prostate, 1989, Volume: 15, Issue:4

    Topics: Acetyl Coenzyme A; Animals; Aspartic Acid; Carbon; Citrates; Citric Acid; Epithelial Cells; Glucose; In Vitro Techniques; Male; Oxidation-Reduction; Oxygen; Prostate; Rats; Rats, Inbred Strains

1989
The effect of testosterone on citrate synthesis and citrate oxidation and a proposed mechanism for regulation of net citrate production in prostate.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1986, Volume: 18, Issue:3

    Topics: Acetyl Coenzyme A; Animals; Aspartate Aminotransferases; Aspartic Acid; Citrates; Citric Acid; Glutamates; Glutamic Acid; Male; Mitochondria; Models, Biological; Orchiectomy; Oxidation-Reduction; Prostate; Rats; Rats, Inbred Strains; Testis; Testosterone

1986
Net citrate production by isolated prostate epithelial cells.
    Enzyme, 1988, Volume: 39, Issue:3

    Topics: Acetyl Coenzyme A; Animals; Aspartate Aminotransferases; Aspartic Acid; Citrates; Citric Acid; Epithelium; Glutamate Dehydrogenase; Ketoglutaric Acids; Male; Mitochondria; Oxaloacetates; Prostate; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains

1988
Presence and regulation of ATP:citrate lyase from the citric acid producing fungus Aspergillus niger.
    Archives of microbiology, 1987, Volume: 147, Issue:1

    Topics: Acetyl Coenzyme A; Aspergillus niger; ATP Citrate (pro-S)-Lyase; Citrates; Citric Acid; Magnesium; Nucleotides

1987
Radioisotopic assay of acetylcarnitine and acetyl-CoA.
    Methods in enzymology, 1986, Volume: 123

    Topics: Acetyl Coenzyme A; Acetylcarnitine; Aspartate Aminotransferases; Carnitine; Citrate (si)-Synthase; Citrates; Citric Acid; Oxaloacetates

1986
Hysteretic behaviour of citrate synthase. The reaction mechanism and the exclusion of synthase being a hysteretic enzyme.
    European journal of biochemistry, 1987, Mar-16, Volume: 163, Issue:3

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Citrate (si)-Synthase; Citrates; Citric Acid; Kinetics; Mathematics; NAD; Oxaloacetates; Oxo-Acid-Lyases; Spectrophotometry

1987
Effect of insulin on ketogenesis and fatty acid synthesis in rat hepatocytes incubated with dichloroacetate.
    Biochimica et biophysica acta, 1985, Mar-21, Volume: 844, Issue:3

    Topics: Acetates; Acetyl Coenzyme A; Animals; Carbon Dioxide; Citrates; Citric Acid; Dichloroacetic Acid; Enzyme Activation; Fatty Acids; Female; Insulin; Ketone Bodies; Liver; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains

1985
Inhibition of lipid synthesis by beta beta'-tetramethyl-substituted, C14-C22, alpha, omega-dicarboxylic acids in cultured rat hepatocytes.
    The Journal of biological chemistry, 1985, Jul-15, Volume: 260, Issue:14

    Topics: Acetyl Coenzyme A; Animals; Biological Transport; Cells, Cultured; Cholesterol; Citrates; Citric Acid; Dicarboxylic Acids; Dose-Response Relationship, Drug; Glucose; Lipids; Liver; Malonyl Coenzyme A; Methylation; Mitochondria, Liver; Palmitic Acid; Palmitic Acids; Rats; Time Factors

1985
Inhibitory effects of sulfhydryl reagents on acetyl-CoA carboxylase from rat mammary gland.
    Biochimica et biophysica acta, 1984, Sep-11, Volume: 789, Issue:2

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Adenosine Triphosphate; Animals; Centrifugation, Density Gradient; Citrates; Citric Acid; Coenzyme A; Female; Hydroxymercuribenzoates; Lactation; Ligases; Mammary Glands, Animal; Palmitoyl Coenzyme A; Pregnancy; Rats

1984
Glutamate dehydrogenase and a proposed glutamate-aspartate pathway for citrate synthesis in rat ventral prostate.
    The Journal of urology, 1984, Volume: 132, Issue:6

    Topics: Acetyl Coenzyme A; Animals; Aspartic Acid; Citrates; Citric Acid; Deamination; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Ketoglutaric Acids; Kidney; Male; Mitochondria; Prostate; Rats; Rats, Inbred Strains

1984
Tricarboxylic acid cycle intermediates and the control of fatty acid synthesis and ketogenesis.
    Current topics in cellular regulation, 1981, Volume: 18

    Topics: Acetyl Coenzyme A; Animals; Bucladesine; Cells, Cultured; Chickens; Citrates; Citric Acid; Citric Acid Cycle; Cyclic AMP; Fatty Acid Synthases; Fatty Acids; Glucagon; Ketone Bodies; Liver; Meglutol

1981
Acetylcoenzyme A and acetylcholine in slices of rat caudate nuclei incubated with (-)-hydroxycitrate, citrate, and EGTA.
    Journal of neurochemistry, 1982, Volume: 39, Issue:3

    Topics: Acetyl Coenzyme A; Acetylcholine; Animals; Caudate Nucleus; Citrates; Citric Acid; Egtazic Acid; Ethylene Glycols; In Vitro Techniques; Kinetics; Male; Rats; Rats, Inbred Strains

1982
Citrate synthesis in intact rat-liver mitochondria is irreversible.
    European journal of biochemistry, 1982, Volume: 122, Issue:2

    Topics: Acetyl Coenzyme A; Animals; Citrates; Citric Acid; Female; Malates; Mitochondria, Liver; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains

1982
The contribution of citrate to the synthesis of acetyl units in synaptosomes of developing rat brain.
    Journal of neurochemistry, 1982, Volume: 38, Issue:5

    Topics: Acetyl Coenzyme A; Animals; ATP Citrate (pro-S)-Lyase; Brain; Choline O-Acetyltransferase; Citrate (si)-Synthase; Citrates; Citric Acid; Female; Malates; Male; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Rats; Synaptosomes

1982
Importance of the modulation of glycolysis in the control of lactate metabolism by fatty acids in isolated hepatocytes from fed rats.
    Archives of biochemistry and biophysics, 1994, Volume: 309, Issue:2

    Topics: Acetyl Coenzyme A; Animals; Butyrates; Butyric Acid; Caprylates; Citrates; Citric Acid; Fatty Acids; Fructosediphosphates; Glycolysis; Ketone Bodies; Lactates; Lactic Acid; Liver; Male; Oleic Acid; Oleic Acids; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar

1994
Effect of high FFA on glycogenolysis in oxidative rat hindlimb muscles during twitch stimulation.
    The American journal of physiology, 1996, Volume: 270, Issue:4 Pt 2

    Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Animals; Citric Acid; Electric Stimulation; Fatty Acids, Nonesterified; Glucose; Glycogen; Hindlimb; Lactic Acid; Male; Muscle Contraction; Muscles; Oxidation-Reduction; Oxygen Consumption; Phosphocreatine; Rats; Rats, Sprague-Dawley

1996
Effect of aluminum on acetyl-CoA and acetylcholine metabolism in nerve terminals.
    Journal of neurochemistry, 1998, Volume: 70, Issue:3

    Topics: Acetyl Coenzyme A; Acetylcholine; Aluminum; Animals; Calcium Channel Blockers; Cell Compartmentation; Citric Acid; Male; Mitochondria; Nerve Endings; Phosphates; Potassium; Pyruvic Acid; Rats; Rats, Wistar; Synaptosomes; Verapamil

1998
Effects of changes in three catalytic residues on the relative stabilities of some of the intermediates and transition states in the citrate synthase reaction.
    Biochemistry, 1998, Jul-07, Volume: 37, Issue:27

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Amino Acid Substitution; Animals; Arginine; Asparagine; Binding Sites; Catalysis; Circular Dichroism; Citrate (si)-Synthase; Citric Acid; Enzyme Stability; Glutamine; Glycine; Histidine; Hydrolysis; Kinetics; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Oxaloacetates; Protons; Solvents; Substrate Specificity; Swine

1998
Properties of Aspergillus niger citrate synthase and effects of citA overexpression on citric acid production.
    FEMS microbiology letters, 2000, Mar-01, Volume: 184, Issue:1

    Topics: Acetyl Coenzyme A; Amino Acid Sequence; Aspergillus niger; Citrate (si)-Synthase; Citric Acid; Cloning, Molecular; DNA, Complementary; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Kinetics; Molecular Sequence Data; Oxaloacetates; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Species Specificity; Transformation, Genetic

2000
Kinetics and mechanism of the citrate synthase from the thermophilic archaeon Thermoplasma acidophilum.
    Biochemistry, 2000, Mar-07, Volume: 39, Issue:9

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Circular Dichroism; Citrate (si)-Synthase; Citric Acid; Coenzyme A; Enzyme Activation; Enzyme Inhibitors; Hydrogen-Ion Concentration; Isoelectric Point; Kinetics; Nuclear Magnetic Resonance, Biomolecular; Oxaloacetic Acid; Protons; Solvents; Substrate Specificity; Swine; Temperature; Thermoplasma

2000
Citrate release by perfused rat hearts: a window on mitochondrial cataplerosis.
    American journal of physiology. Endocrinology and metabolism, 2000, Volume: 278, Issue:5

    Topics: Acetyl Coenzyme A; Animals; Caprylates; Citric Acid; Energy Metabolism; Gas Chromatography-Mass Spectrometry; Glucose; In Vitro Techniques; Indicator Dilution Techniques; Insulin; L-Lactate Dehydrogenase; Lactic Acid; Male; Mitochondria, Heart; Myocardium; Oxaloacetic Acid; Pyruvic Acid; Rats; Rats, Sprague-Dawley

2000
Aluminium tolerance in plants and the complexing role of organic acids.
    Trends in plant science, 2001, Volume: 6, Issue:6

    Topics: Acetyl Coenzyme A; Aluminum; Anions; Carboxylic Acids; Citric Acid; Cytosol; Edible Grain; Hydrogen-Ion Concentration; Ion Channels; Organelles; Oxidation-Reduction; Plant Physiological Phenomena; Plant Roots; Soil

2001
Probing the link between citrate and malonyl-CoA in perfused rat hearts.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:4

    Topics: Acetyl Coenzyme A; Animals; ATP Citrate (pro-S)-Lyase; Carbon Isotopes; Citrates; Citric Acid; Citric Acid Cycle; Gas Chromatography-Mass Spectrometry; In Vitro Techniques; Male; Malonyl Coenzyme A; Myocardial Contraction; Myocardium; Perfusion; Pyruvic Acid; Rats; Rats, Sprague-Dawley

2002
Enzymatic synthesis of citric acid. V. Reaction of acetyl coenzyme A.
    The Journal of biological chemistry, 1952, Volume: 198, Issue:1

    Topics: Acetyl Coenzyme A; Citrates; Citric Acid; Coenzymes

1952
THE EQUILIBRIUM OF THE REACTION CATALYSED BY CITRATE OXALOACETATE-LYASE.
    The Biochemical journal, 1965, Volume: 94

    Topics: Acetyl Coenzyme A; Biochemical Phenomena; Biochemistry; Catalysis; Chemistry Techniques, Analytical; Citrates; Citric Acid; Coenzyme A; Enterobacter aerogenes; Hydrolysis; Lyases; Magnesium; Multienzyme Complexes; Oxaloacetates; Oxaloacetic Acid; Oxo-Acid-Lyases; Research; Thermodynamics

1965
Mechanism of formation and accumulation of citric acid in Aspergillus niger. Part II. Citric acid formation and acetyl coenzyme A deacylase in a citric acid producing strain of Aspergillus niger.
    Enzymologia, 1959, Sep-01, Volume: 21

    Topics: Acetyl Coenzyme A; Aspergillus; Aspergillus niger; Biochemical Phenomena; Citrates; Citric Acid; Coenzymes

1959
Probing peroxisomal beta-oxidation and the labelling of acetyl-CoA proxies with [1-(13C)]octanoate and [3-(13C)]octanoate in the perfused rat liver.
    The Biochemical journal, 2005, Jul-15, Volume: 389, Issue:Pt 2

    Topics: Acetates; Acetyl Coenzyme A; Acetylcarnitine; Animals; Caprylates; Carbon Isotopes; Citric Acid; Isotope Labeling; Ketone Bodies; Liver; Male; Malonyl Coenzyme A; Mitochondria, Liver; Oxidation-Reduction; Perfusion; Peroxisomes; Rats; Rats, Sprague-Dawley

2005
Methods for extracting biochemical information from bacterial Raman spectra: an explorative study on Cupriavidus metallidurans.
    Analytica chimica acta, 2007, Mar-07, Volume: 585, Issue:2

    Topics: Acetyl Coenzyme A; Bacteria; Chemistry Techniques, Analytical; Citric Acid; Citric Acid Cycle; Cupriavidus; Models, Chemical; Phenylalanine; Spectrum Analysis, Raman; Tyrosine

2007
Insights into the autotrophic CO2 fixation pathway of the archaeon Ignicoccus hospitalis: comprehensive analysis of the central carbon metabolism.
    Journal of bacteriology, 2007, Volume: 189, Issue:11

    Topics: 2-Aminoadipic Acid; Acetyl Coenzyme A; Archaea; Autotrophic Processes; Carbon; Carbon Dioxide; Carbon Isotopes; Citrate (si)-Synthase; Citric Acid; Fructose-Bisphosphate Aldolase; Gluconeogenesis; Glycolysis; Hexosephosphates; Isoleucine; Lysine; Magnetic Resonance Spectroscopy; Malates; Models, Biological; Molecular Structure; Oxaloacetic Acid; Pentosephosphates; Phosphoenolpyruvate; Phosphoenolpyruvate Carboxylase; Pyruvate Synthase; Pyruvates

2007
Biochemistry. A glucose-to-gene link.
    Science (New York, N.Y.), 2009, May-22, Volume: 324, Issue:5930

    Topics: Acetate-CoA Ligase; Acetyl Coenzyme A; Acetylation; Animals; ATP Citrate (pro-S)-Lyase; Cell Nucleus; Cells, Cultured; Chromatin; Citric Acid; Gene Expression Regulation; Glucose; Glycolysis; Histones; Humans; Transcription, Genetic

2009
ATP-citrate lyase links cellular metabolism to histone acetylation.
    Science (New York, N.Y.), 2009, May-22, Volume: 324, Issue:5930

    Topics: 3T3 Cells; Acetate-CoA Ligase; Acetyl Coenzyme A; Acetylation; Adipocytes; Animals; ATP Citrate (pro-S)-Lyase; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Citric Acid; Cytoplasm; Gene Expression Regulation; Glucose; Glycolysis; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Intercellular Signaling Peptides and Proteins; Interleukin-3; Mice; RNA Interference; Transcription, Genetic

2009
Acetate produced in the mitochondrion is the essential precursor for lipid biosynthesis in procyclic trypanosomes.
    Proceedings of the National Academy of Sciences of the United States of America, 2009, Aug-04, Volume: 106, Issue:31

    Topics: Acetate-CoA Ligase; Acetates; Acetyl Coenzyme A; Animals; Citric Acid; Lipids; Malates; Mitochondria; Multienzyme Complexes; Oxo-Acid-Lyases; RNA Interference; Trypanosoma brucei brucei

2009
Acetyl-CoA and acetylcholine metabolism in nerve terminal compartment of thiamine deficient rat brain.
    Journal of neurochemistry, 2010, Volume: 115, Issue:2

    Topics: Acetyl Coenzyme A; Acetylcholine; Animals; Brain; Citric Acid; Ketoglutarate Dehydrogenase Complex; Ketoglutaric Acids; Ketone Oxidoreductases; Lactic Acid; Male; Models, Biological; Nerve Endings; Pyrithiamine; Pyruvic Acid; Rats; Rats, Wistar; Synaptosomes; Thiamine Deficiency

2010
Reductive carboxylation supports growth in tumour cells with defective mitochondria.
    Nature, 2011, Nov-20, Volume: 481, Issue:7381

    Topics: Acetyl Coenzyme A; Animals; Carcinoma, Renal Cell; Cell Hypoxia; Cell Line, Tumor; Citric Acid; Electron Transport; Electron Transport Complex I; Electron Transport Complex III; Fumarate Hydratase; Glucose; Glutamine; Humans; Isocitrate Dehydrogenase; Kidney Neoplasms; Mice; Mitochondria; NADP; Neoplasms

2011
The cycling of acetyl-coenzyme A through acetylcarnitine buffers cardiac substrate supply: a hyperpolarized 13C magnetic resonance study.
    Circulation. Cardiovascular imaging, 2012, Volume: 5, Issue:2

    Topics: Acetyl Coenzyme A; Acetylcarnitine; Animals; Carbon Isotopes; Carnitine O-Acetyltransferase; Citric Acid; Energy Metabolism; Glutamic Acid; Magnetic Resonance Spectroscopy; Male; Myocardial Contraction; Myocardium; Oxidation-Reduction; Postprandial Period; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Rats; Rats, Wistar; Time Factors

2012
A defect in ATP-citrate lyase links acetyl-CoA production, virulence factor elaboration and virulence in Cryptococcus neoformans.
    Molecular microbiology, 2012, Volume: 86, Issue:6

    Topics: Acetyl Coenzyme A; Amino Acid Sequence; Animals; ATP Citrate (pro-S)-Lyase; Cell Line; Citric Acid; Cryptococcosis; Cryptococcus neoformans; Culture Media; Disease Models, Animal; Glucose; INDEL Mutation; Macrophages; Mice; Microbial Viability; Models, Molecular; Molecular Sequence Data; Phylogeny; Sequence Homology, Amino Acid; Virulence; Virulence Factors

2012
Central metabolism controls transcription of a virulence gene regulator in Vibrio cholerae.
    Microbiology (Reading, England), 2013, Volume: 159, Issue:Pt 4

    Topics: Acetates; Acetyl Coenzyme A; Amino Acids; Bacterial Proteins; Citric Acid; Citric Acid Cycle; Culture Media; DNA Transposable Elements; Gene Expression Regulation, Bacterial; Mutagenesis, Insertional; Oxygen Consumption; Transcription Factors; Vibrio cholerae O1; Virulence

2013
Physiological characterization of ATP-citrate lyase in Aspergillus niger.
    Journal of industrial microbiology & biotechnology, 2014, Volume: 41, Issue:4

    Topics: Acetyl Coenzyme A; Aspergillus niger; ATP Citrate (pro-S)-Lyase; Citric Acid; Gene Deletion; Spores, Fungal

2014
Expression of citrate carrier gene is activated by ER stress effectors XBP1 and ATF6α, binding to an UPRE in its promoter.
    Biochimica et biophysica acta, 2015, Volume: 1849, Issue:1

    Topics: Acetyl Coenzyme A; Activating Transcription Factor 6; Animals; Carrier Proteins; Citric Acid; DNA-Binding Proteins; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Hep G2 Cells; Humans; Promoter Regions, Genetic; Protein Folding; Protein Processing, Post-Translational; Rats; Regulatory Factor X Transcription Factors; Signal Transduction; Transcription Factors; Unfolded Protein Response; X-Box Binding Protein 1

2015
Glutamine oxidation maintains the TCA cycle and cell survival during impaired mitochondrial pyruvate transport.
    Molecular cell, 2014, Nov-06, Volume: 56, Issue:3

    Topics: Acetyl Coenzyme A; Animals; Antineoplastic Agents; Biological Transport; Catechin; Cell Line, Tumor; Cell Survival; Citric Acid; Citric Acid Cycle; Coumaric Acids; Glucose; Glutamine; Humans; Lipid Metabolism; Male; Mice, Nude; Mitochondria; Oxidation-Reduction; Pyruvic Acid; Sugar Alcohol Dehydrogenases; Tumor Burden; Xenograft Model Antitumor Assays

2014
Changes in the Acetylome and Succinylome of Bacillus subtilis in Response to Carbon Source.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Acetyl Coenzyme A; Acetylation; Acyl Coenzyme A; Amino Acids, Branched-Chain; Bacillus subtilis; Blotting, Western; Carbon; Citric Acid; Gene Expression Regulation, Bacterial; Lysine; Mass Spectrometry; Metabolic Networks and Pathways; Proteomics; Purines; Succinic Acid

2015
Differential effects of octanoate and heptanoate on myocardial metabolism during extracorporeal membrane oxygenation in an infant swine model.
    American journal of physiology. Heart and circulatory physiology, 2015, Volume: 309, Issue:7

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Caprylates; Carbon Isotopes; Citric Acid; Citric Acid Cycle; Energy Metabolism; Extracorporeal Membrane Oxygenation; Gas Chromatography-Mass Spectrometry; Heart; Heptanoates; Leucine; Lipid Metabolism; Magnetic Resonance Spectroscopy; Male; Mitochondria, Heart; Models, Animal; Myocardium; Oxidation-Reduction; Sus scrofa; Swine

2015
AβPP-Transgenic 2576 Mice Mimic Cell Type-Specific Aspects of Acetyl-CoA-Linked Metabolic Deficits in Alzheimer's Disease.
    Journal of Alzheimer's disease : JAD, 2015, Volume: 48, Issue:4

    Topics: Acetyl Coenzyme A; Acetylcholine; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Citric Acid; Cytoplasm; Disease Models, Animal; Female; Humans; Ketoglutaric Acids; Male; Mice, Transgenic; Mitochondria; Mutation; Neuroglia; Neurons; Peptide Fragments; Pyruvic Acid; Synaptosomes

2015
Integrated, Step-Wise, Mass-Isotopomeric Flux Analysis of the TCA Cycle.
    Cell metabolism, 2015, Nov-03, Volume: 22, Issue:5

    Topics: Acetyl Coenzyme A; Animals; Carbon Isotopes; Citrates; Citric Acid; Citric Acid Cycle; Insulin; Isocitrate Dehydrogenase; Oxaloacetic Acid; Oxidation-Reduction; Oxygen Consumption; Pyruvate Carboxylase; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Rats

2015
Multi-omics analysis reveals regulators of the response to nitrogen limitation in Yarrowia lipolytica.
    BMC genomics, 2016, Feb-25, Volume: 17

    Topics: Acetyl Coenzyme A; Citric Acid; DNA, Fungal; Fungal Proteins; Lipid Metabolism; Metabolome; Nitrogen; Oxidation-Reduction; Phosphorylation; Proteome; Yarrowia

2016
Wnt Protein Signaling Reduces Nuclear Acetyl-CoA Levels to Suppress Gene Expression during Osteoblast Differentiation.
    The Journal of biological chemistry, 2016, Jun-17, Volume: 291, Issue:25

    Topics: Acetyl Coenzyme A; Acetylation; Animals; Cell Differentiation; Cell Line; Cell Nucleus; Citric Acid; Citric Acid Cycle; Gene Expression; Gene Silencing; Glucose; Histones; Mice; Osteoblasts; Protein Processing, Post-Translational; Wnt Signaling Pathway; Wnt3A Protein

2016
Mass spectrometry analysis shows the biosynthetic pathways supported by pyruvate carboxylase in highly invasive breast cancer cells.
    Biochimica et biophysica acta. Molecular basis of disease, 2017, Volume: 1863, Issue:2

    Topics: Acetyl Coenzyme A; Aspartic Acid; Biosynthetic Pathways; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Citric Acid; Female; Gene Knockdown Techniques; Glycine; Glycolysis; Humans; Lactic Acid; Malates; Mass Spectrometry; Metabolic Networks and Pathways; Neoplasm Invasiveness; Nucleotides; Pyruvate Carboxylase; Pyruvic Acid; Serine

2017
ATP-citrate lyase is essential for high glucose-induced histone hyperacetylation and fibrogenic gene upregulation in mesangial cells.
    American journal of physiology. Renal physiology, 2017, Aug-01, Volume: 313, Issue:2

    Topics: Acetyl Coenzyme A; Acetylation; Active Transport, Cell Nucleus; Animals; ATP Citrate (pro-S)-Lyase; Cell Line, Transformed; Citric Acid; Collagen Type IV; Connective Tissue Growth Factor; Diabetic Nephropathies; Epigenesis, Genetic; Fibronectins; Fibrosis; Glucose; Histones; Mesangial Cells; Mice; Protein Processing, Post-Translational; RNA Interference; Time Factors; Transfection; Transforming Growth Factor beta1; Transforming Growth Factor beta3; Up-Regulation

2017
Reversibility of citrate synthase allows autotrophic growth of a thermophilic bacterium.
    Science (New York, N.Y.), 2018, Feb-02, Volume: 359, Issue:6375

    Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Autotrophic Processes; Carbon Cycle; Carbon Dioxide; Citrate (si)-Synthase; Citric Acid; Deltaproteobacteria; Oxaloacetic Acid

2018
Metabolic reprogramming enables hepatocarcinoma cells to efficiently adapt and survive to a nutrient-restricted microenvironment.
    Cell cycle (Georgetown, Tex.), 2018, Volume: 17, Issue:7

    Topics: Acetyl Coenzyme A; Adaptation, Physiological; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Survival; Citric Acid; Citric Acid Cycle; Fatty Acids; Gene Expression Regulation, Neoplastic; Glucose; Glucose Transporter Type 1; Glycolysis; Hep G2 Cells; Hexokinase; Humans; L-Lactate Dehydrogenase; Lipid Metabolism; Liver Neoplasms; Malonyl Coenzyme A; Mice; Signal Transduction; Survival Analysis; Triglycerides

2018
New Insights into Behçet's Syndrome Metabolic Reprogramming: Citrate Pathway Dysregulation.
    Mediators of inflammation, 2018, Volume: 2018

    Topics: Acetyl Coenzyme A; Adult; Anion Transport Proteins; ATP Citrate (pro-S)-Lyase; Behcet Syndrome; Case-Control Studies; Citric Acid; Female; Humans; Inflammation; Leukocytes, Mononuclear; Macrophages; Male; Metabolic Syndrome; Middle Aged; Mitochondria; Mitochondrial Proteins; Organic Anion Transporters; Oxaloacetic Acid; RNA, Messenger; Up-Regulation

2018
Mitochondrial Citrate Transporters CtpA and YhmA Are Required for Extracellular Citric Acid Accumulation and Contribute to Cytosolic Acetyl Coenzyme A Generation in Aspergillus luchuensis mut.
    Applied and environmental microbiology, 2019, 04-15, Volume: 85, Issue:8

    Topics: Acetates; Acetyl Coenzyme A; Amino Acids; Aspergillus; Carrier Proteins; Citrates; Citric Acid; Cytosol; Fermentation; Gene Expression Profiling; Gene Knockdown Techniques; Genes, Fungal; Malates; Mitochondria; Phenotype; Saccharomyces cerevisiae

2019
Citrate synthase from Synechocystis is a distinct class of bacterial citrate synthase.
    Scientific reports, 2019, 04-15, Volume: 9, Issue:1

    Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Bacterial Proteins; Calcium Chloride; Carbon Dioxide; Citrate (si)-Synthase; Citric Acid; Citric Acid Cycle; Enzyme Activation; Magnesium Chloride; Synechocystis

2019
Impact of Five Succinate Dehydrogenase Inhibitors on DON Biosynthesis of
    Toxins, 2019, 05-15, Volume: 11, Issue:5

    Topics: Acetyl Coenzyme A; Citric Acid; Fungal Proteins; Fungicides, Industrial; Fusarium; Gene Expression; Glycolysis; Isocitrate Dehydrogenase; Mitochondria; Mycelium; Plant Diseases; Pyruvic Acid; Spores, Fungal; Succinate Dehydrogenase; Trichothecenes; Triticum

2019
Inhibition of the mitochondrial citrate carrier, Slc25a1, reverts steatosis, glucose intolerance, and inflammation in preclinical models of NAFLD/NASH.
    Cell death and differentiation, 2020, Volume: 27, Issue:7

    Topics: Acetyl Coenzyme A; Animals; Blood Glucose; Carrier Proteins; Cell Polarity; Citric Acid; Diet, High-Fat; Disease Models, Animal; Down-Regulation; Fasting; Gluconeogenesis; Glucose Intolerance; Hepatomegaly; Humans; Hyperglycemia; Inflammation; Insulin Resistance; Interleukin-6; Lipogenesis; Liver; Macrophages; Male; Mice; Mice, Inbred C57BL; Mitochondria; Non-alcoholic Fatty Liver Disease; Obesity; Phenotype; Time Factors; Triglycerides; Tumor Necrosis Factor-alpha

2020
Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate.
    Nature, 2020, Volume: 579, Issue:7800

    Topics: Acetate-CoA Ligase; Acetates; Acetyl Coenzyme A; Animals; ATP Citrate (pro-S)-Lyase; Citric Acid; Dietary Sugars; Fatty Acids; Fructose; Gastrointestinal Microbiome; Gene Expression Regulation; Hepatocytes; Isotope Labeling; Lipogenesis; Liver; Male; Mice; Substrate Specificity

2020
Assessment of organic acid accumulation and its related genes in peach.
    Food chemistry, 2021, Jan-01, Volume: 334

    Topics: Acetyl Coenzyme A; Carboxylic Acids; Citric Acid; Fruit; Gene Expression Profiling; Gene Expression Regulation, Plant; Malates; Plant Proteins; Prunus persica; Pyruvic Acid; Vacuoles

2021
Effects of propionate concentration on short-term metabolism in liver explants from dairy cows in the postpartum period.
    Journal of dairy science, 2020, Volume: 103, Issue:12

    Topics: Acetyl Coenzyme A; Animals; Cattle; Citric Acid; Citric Acid Cycle; Dietary Supplements; Dose-Response Relationship, Drug; Female; Fumarates; Gluconeogenesis; Glucose; Lactation; Liver; Malates; Postpartum Period; Propionates

2020
Substrate usage determines carbon flux via the citrate cycle in Helicobacter pylori.
    Molecular microbiology, 2021, Volume: 116, Issue:3

    Topics: Acetyl Coenzyme A; Amino Acids; Aspartic Acid; Carbohydrate Metabolism; Carbon; Carbon Cycle; Citric Acid; Citric Acid Cycle; Glucose; Glutamic Acid; Glyceraldehyde; Glyoxylates; Helicobacter Infections; Helicobacter pylori; Humans; Malates; Metabolic Networks and Pathways; Succinic Acid

2021
Increased expression of SLC25A1/CIC causes an autistic-like phenotype with altered neuron morphology.
    Brain : a journal of neurology, 2022, 04-18, Volume: 145, Issue:2

    Topics: Acetyl Coenzyme A; Animals; Autism Spectrum Disorder; Autistic Disorder; Citric Acid; Humans; Mice; Mitochondrial Proteins; Neurons; Organic Anion Transporters; Phenotype; Proteomics

2022
A Potential Citrate Shunt in Erythrocytes of PKAN Patients Caused by Mutations in Pantothenate Kinase 2.
    Biomolecules, 2022, 02-18, Volume: 12, Issue:2

    Topics: Acetyl Coenzyme A; Citrates; Citric Acid; Erythrocytes; Humans; Iron; Mutation; Neurodegenerative Diseases; Pantothenate Kinase-Associated Neurodegeneration; Phosphotransferases (Alcohol Group Acceptor); Protein Isoforms

2022
The citrate transporters SLC13A5 and SLC25A1 elicit different metabolic responses and phenotypes in the mouse.
    Communications biology, 2023, 09-09, Volume: 6, Issue:1

    Topics: Acetyl Coenzyme A; Acetylation; Animals; Citrates; Citric Acid; Mice; Phenotype

2023