acetone has been researched along with phenobarbital in 60 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (45.00) | 18.7374 |
| 1990's | 27 (45.00) | 18.2507 |
| 2000's | 5 (8.33) | 29.6817 |
| 2010's | 1 (1.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dunn, WJ; Grigoras, S; Koehler, MG | 1 |
| Caron, G; Ermondi, G | 1 |
| Abraham, MH; Acree, WE; Ibrahim, A | 1 |
| Abellán Guillén, A; Cordeiro, MN; Garrido Escudero, A; Morales Helguera, A; Pérez-Garrido, A | 1 |
| Lust, WD; Passonneau, JV; Schwartz, JP | 1 |
| Vainio, H; Zitting, A | 1 |
| Bridges, JW; McPherson, FJ; Parke, DV | 1 |
| Docks, EL; Krishna, G | 1 |
| Grishanova, AIu; Kozlovskaia, NE; Liakhovich, VV; Mishin, VM | 1 |
| Beaune, PH; Carrière, V; Courtois, YA; de Waziers, I; Leroux, JP | 1 |
| Hsieh, CY; Huang, JD | 1 |
| Sipes, IG; Weber, GL | 1 |
| Airoldi, L; De Gregorio, G; Fanelli, R; Magagnotti, C; Moret, M | 1 |
| Elovaara, E; Engström, K; Gelboin, HV; Nakajima, T; Park, SS; Vainio, H | 1 |
| Berthou, F; Dreano, Y; Floch, HH; Lucas, D; Menez, JF | 1 |
| Hong, JY; Ning, SM; Yang, CS; Yoo, JS | 1 |
| Cederbaum, AI; Winters, DK | 1 |
| Eliasson, E; Ingelman-Sundberg, M; Johansson, I | 1 |
| Brady, JF; Ning, SM; Xiao, F; Yang, CS | 1 |
| Aitio, A; Elovaara, E; Vainio, H | 1 |
| Hansen, LL; Lundquist, F | 1 |
| Huang, MT; Lundquist, F; Quistorff, B | 1 |
| Farber, JL; Kyle, ME; Nakae, D; Serroni, A | 1 |
| Hayes, EP; Scala, P; Witz, G | 1 |
| Gangolli, S; Wright, M | 1 |
| Leibman, KC | 1 |
| Hansen, W; Scholz, R; Thurman, RG | 1 |
| Kon, H; Nebert, DW | 1 |
| Scholz, R; Thurman, G | 1 |
| Ikeda, M; Imamura, T; Otsuji, H | 1 |
| Jacobson, M; Kuntzman, R; Levin, W; Lu, AY; West, SB | 1 |
| Anders, MW | 1 |
| Borchert, P; Miller, EC; Miller, JA; Wislocki, PG | 1 |
| Carl, JL; King, LJ; Lao, L | 1 |
| Diamond, L; Gelboin, HV; Leutz, JC; Wiebel, FJ | 1 |
| Coldwell, BB; Trenholm, HL; Wiberg, GS | 1 |
| McMahon, RE; Parli, CJ; Wang, N | 1 |
| Daly, J; Farnsworth, J; Guroff, G; Jerina, D | 1 |
| Anundi, I; Dawson, JR; Moldéus, P; Norbeck, K | 1 |
| Gergely, V; Moldéus, P | 1 |
| Chiba, K; Imai, Y; Kamataki, T; Kitada, M; Kitagawa, H; Sato, R | 1 |
| Malone, A; Richter, E; Schulze, J | 1 |
| Chen, L; Hong, JY; Huang, W; Lee, M; Wang, E; Yang, CS | 1 |
| Ahmed, AE; Burka, LT; Ghanayem, BI; Sanchez, IM | 1 |
| Jenner, AM; Timbrell, JA | 1 |
| Crankshaw, D; Reicks, MM | 1 |
| Jaw, S; Jeffery, EH | 1 |
| Ripel, A; Smith-Kielland, A | 1 |
| Konishi, H; Morita, K; Yamaji, A | 1 |
| Buko, VU; Sadovnichy, VV | 1 |
| Barnett, CR; Clarke, J; Coulter, J; Flatt, PR | 1 |
| Elovaara, E; Lautala, P; Luukkanen, L; Taskinen, J; Vainio, H | 1 |
| De Curtis, V; Fabrizi, L; Gemma, S; Gervasi, P; Testai, E; Vittozzi, L | 1 |
| Løkken, T; Mortensen, B; Nilsen, OG; Zahlsen, K | 1 |
| Fisher, MB; Guan, X; Koop, DR; Lang, DH; Rettie, AE; Zheng, YM | 1 |
| Carlson, GP; DeNicola, DB; Felten, RK | 1 |
| Amato, G; Gervasi, PG; Giorgi, M; Longo, V; Marini, S; Mazzaccaro, A | 1 |
| Brown, D; Scott, JG; Wen, Z; Zhang, L | 1 |
| Kyo, S | 1 |
| Fenves, AZ; Massoth, LR; Mojtahed, A; Nisavic, M | 1 |
60 other study(ies) available for acetone and phenobarbital
| Article | Year |
|---|---|
The role of solvent-accessible surface area in determining partition coefficients.
Topics: Diffusion; Solubility; Solvents; Structure-Activity Relationship | 1987 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization | 2008 |
Convenient QSAR model for predicting the complexation of structurally diverse compounds with beta-cyclodextrins.
Topics: beta-Cyclodextrins; Hydrophobic and Hydrophilic Interactions; Organic Chemicals; Quantitative Structure-Activity Relationship | 2009 |
Glycolytic metabolism in cultured cells of the nervous system. I. Glucose transport and metabolism in the C-6 glioma cell line.
Topics: Acetone; Biological Transport, Active; Cell Line; Fluoroacetates; Glioma; Glucose; Glycolysis; Hydrogen-Ion Concentration; Iodoacetates; Kinetics; Lactates; Phenobarbital; Pyruvates; Valinomycin | 1975 |
Interaction of styrene and acetone with drug biotransformation enzymes in rat liver.
Topics: Acetone; Animals; Binding Sites; Biotransformation; Cytochrome P-450 Enzyme System; Drug Interactions; Endoplasmic Reticulum; Glutathione; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Styrenes; Sulfhydryl Compounds | 1978 |
The effects of benzopyrene and safrole on biphenyl 2-hydroxylase and other drug-metabolizing enzymes.
Topics: Acetone; Aniline Hydroxylase; Animals; Benzopyrene Hydroxylase; Benzopyrenes; Catechol Oxidase; Cricetinae; Cytochromes; Dactinomycin; Dioxoles; Male; Methylcholanthrene; Metyrapone; Mice; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Nikethamide; Phenobarbital; Rats; Safrole | 1976 |
The role of glutathione in chloroform-induced hepatotoxicity.
Topics: Acetone; Alkanes; Animals; Carbon Tetrachloride; Chloroform; Cysteamine; Cysteine; Dose-Response Relationship, Drug; Glutathione; Kidney; Lens, Crystalline; Liver; Male; Maleates; Methylcholanthrene; Phenobarbital; Propranolol; Rats | 1976 |
[The effect of tetrahydrofuran on the microsomal monooxygenase system in vitro and in vivo].
Topics: Acetone; Animals; Enzyme Induction; Furans; Isoniazid; Male; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rats; Rats, Wistar | 1992 |
Cytochrome P450 induction and mutagenicity of 2-aminoanthracene (2AA) in rat liver and gut.
Topics: Acetone; Animals; Anthracenes; Benzoflavones; beta-Naphthoflavone; Biotransformation; Blotting, Western; Colon; Cytochrome P-450 Enzyme System; Dexamethasone; Intestine, Small; Liver; Male; Mutagenicity Tests; Mutagens; Phenobarbital; Rats; Rats, Inbred Strains; Salmonella typhimurium | 1992 |
Two-dimensional high-performance liquid chromatographic method to assay p-hydroxyphenylphenylhydantoin enantiomers in biological fluids and stereoselectivity of enzyme induction in phenytoin metabolism.
Topics: Acetone; Animals; Aroclors; Chlorodiphenyl (54% Chlorine); Chromatography, High Pressure Liquid; Cimetidine; Dexamethasone; Diazepam; Enzyme Induction; Female; Ketoconazole; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Phenytoin; Rats; Safrole; Sex Characteristics; Stereoisomerism; Sulfaphenazole | 1992 |
In vitro metabolism and bioactivation of 1,2,3-trichloropropane.
Topics: Acetone; Animals; Biotransformation; Cytosol; Humans; Male; Microsomes, Liver; NADP; Phenobarbital; Propane; Rats; Rats, Inbred Strains | 1992 |
In vitro metabolism of bladder carcinogenic nitrosamines by rat liver and urothelial cells.
Topics: Acetone; Animals; Butylhydroxybutylnitrosamine; Carcinogens; Epithelium; Hydroxylation; Liver; Liver Extracts; Male; Nitrogen; Nitrosamines; Phenobarbital; Rats; Urinary Bladder | 1992 |
Metabolism of inhaled styrene in acetone-, phenobarbital- and 3-methylcholanthrene-pretreated rats: stimulation and stereochemical effects by induction of cytochromes P450IIE1, P450IIB and P450IA.
Topics: Acetone; Administration, Inhalation; Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Enzyme Induction; Kidney; Lung; Male; Methylcholanthrene; Microsomes, Liver; Oxidoreductases; Oxidoreductases, N-Demethylating; Phenobarbital; Rats; Rats, Inbred Strains; Stereoisomerism; Styrenes | 1991 |
Ethanol-inducible cytochrome P-450: assessment of substrates' specific chemical probes in rat liver microsomes.
Topics: Acetone; Alcoholism; Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethanol; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Substrate Specificity | 1990 |
Roles of dietary corn oil in the regulation of cytochromes P450 and glutathione S-transferases in rat liver.
Topics: Acetone; Animals; Blotting, Western; Body Weight; Corn Oil; Cytochrome P-450 Enzyme System; Dietary Fats, Unsaturated; Enzyme Induction; Glutathione Transferase; Isoenzymes; Liver; Male; Microsomes, Liver; Organ Size; Phenobarbital; Rats; Rats, Inbred Strains; RNA, Messenger; Testosterone | 1990 |
Oxidation of glycerol to formaldehyde by rat liver microsomes. Effects of cytochrome P-450 inducing agents.
Topics: Acetone; Aldehyde Oxidoreductases; Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethanol; Fomepizole; Formaldehyde; Glycerol; Isoenzymes; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; NAD; Oxidation-Reduction; Phenobarbital; Pyrazoles; Rats; Rats, Inbred Strains | 1990 |
Substrate-, hormone-, and cAMP-regulated cytochrome P450 degradation.
Topics: 1-Propanol; Acetone; Animals; Cells, Cultured; Cytochrome P-450 Enzyme System; Ethanol; Glucagon; Kinetics; Liver; Phenobarbital; Phosphorylation; Rats; Rats, Inbred Strains; Substrate Specificity | 1990 |
Metabolism of methyl tertiary-butyl ether by rat hepatic microsomes.
Topics: Acetone; Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethers; Isoenzymes; Male; Methyl Ethers; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Solvents | 1990 |
Pulmonary toxicity of inhaled styrene in acetone-, phenobarbital- and 3-methylcholanthrene-treated rats.
Topics: Acetone; Animals; Body Weight; Cytochrome P-450 Enzyme System; Glutathione; Lung; Lung Diseases; Male; Methylcholanthrene; Mixed Function Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains; Styrene; Styrenes; Sulfides | 1990 |
Deuterium isotope effects as a tool in the study of ethanol oxidation in rat liver microsomes.
Topics: Acetone; Amides; Animals; Azides; Carbon Radioisotopes; Deuterium; Ethanol; Female; Hydrogen Peroxide; Kinetics; Microsomes, Liver; Oxidation-Reduction; Pentetic Acid; Phenobarbital; Rats; Rats, Inbred Strains; Superoxides; Thiourea | 1989 |
Deuterium isotope effects on ethanol oxidation in perfused rat liver and in rats and rabbits in vivo: application to determine the contribution of various pathways.
Topics: Acetaldehyde; Acetone; Amides; Anesthesia; Animals; Deuterium; Ethanol; Female; Kinetics; Liver; Microsomes, Liver; Oxidation-Reduction; Oxygen; Perfusion; Phenobarbital; Rabbits; Rats | 1989 |
1,3-(2-Chloroethyl)-1-nitrosourea potentiates the toxicity of acetaminophen both in the phenobarbital-induced rat and in hepatocytes cultured from such animals.
Topics: Acetaminophen; Acetone; Carmustine; Cell Survival; Deferoxamine; Drug Synergism; Enzyme Induction; Glutathione; Liver; Male; Maleates; Methylcholanthrene; Phenobarbital; Phenylenediamines | 1988 |
Lipid composition of liver microsomes from rats treated with acetone.
Topics: Acetone; Acetonitriles; Administration, Oral; Aminopyrine; Animals; Cholesterol; Cytochrome P-450 Enzyme System; Female; Microsomes, Liver; Phenobarbital; Phospholipids; Rats; Rats, Inbred Strains | 1986 |
The histochemical demonstration of aniline hydroxylase activity in rat liver.
Topics: Acetone; Aniline Compounds; Animals; Carbon Monoxide; Cyanides; Diazonium Compounds; Ethanol; Female; Formaldehyde; Histocytochemistry; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Nitrogen; Phenobarbital; Phenols; Rats; Staining and Labeling; Time Factors | 1971 |
Reduction of ketones in liver cytosol.
Topics: Acetone; Acetophenones; Animals; Benzophenones; Chromatography, Gas; Chromatography, Thin Layer; Cytosol; Ketone Oxidoreductases; Ketones; Kidney; Liver; Lung; Male; Myocardium; NAD; NADP; Phenobarbital; Rabbits; Rats | 1971 |
Interaction of mixed-function oxidation with biosynthetic processes. 1. Inhibition of gluconeogenesis by aminopyrine in perfused rat liver.
Topics: Acetone; Aminopyrine; Animals; Depression, Chemical; Flavins; Fluorometry; Gluconeogenesis; In Vitro Techniques; Kinetics; Lactates; Liver; Male; NAD; NADP; Oxidation-Reduction; Oxygen Consumption; Perfusion; Phenobarbital; Rats | 1973 |
Genetic regulation of aryl hydrocarbon hydroxylase induction. V. Specific changes in spin state of cytochrome P 450 from genetically responsive animals.
Topics: Acetone; Animals; Benzopyrenes; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Enzyme Induction; Female; Flavonoids; Kidney; Male; Methylcholanthrene; Mice; Mice, Inbred Strains; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; Molecular Biology; Naphthalenes; Phenobarbital; Protein Binding; Rabbits; Rats; Surface-Active Agents; Temperature | 1973 |
Interaction of gluconeogenesis and mixed function oxidation.
Topics: Acetone; Aminopyrine; Animals; Gluconeogenesis; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; In Vitro Techniques; Lactates; Liver; Microsomes, Liver; NADP; Perfusion; Phenobarbital; Rats; Trioses | 1970 |
Comparative studies on aniline hydroxylation and p-nitrotoluene hydroxylation by the liver.
Topics: Acetamides; Acetone; Aniline Compounds; Animals; Biotransformation; Cricetinae; Depression, Chemical; Guinea Pigs; Hydroxylation; Kinetics; Liver; Methylcholanthrene; Metyrapone; Mice; Phenobarbital; Pyridines; Rabbits; Rats; Sex Factors; Stimulation, Chemical; Toluene | 1972 |
Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds, and endogenous substrates. IV. Hydroxylation of aniline.
Topics: Acetone; Aniline Compounds; Animals; Benzopyrenes; Benzphetamine; Carbon Isotopes; Cytochrome P-450 Enzyme System; Cytochromes; Enzyme Activation; Hydroxylation; Lipids; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rats; Spectrophotometry | 1972 |
Effect of phenobarbital and 3-methylcholanthrene administration on the in vitro enhancement of microsomal aromatic hydroxylation.
Topics: Acetanilides; Acetone; Aniline Compounds; Animals; Benzphetamine; Hydroxylation; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Protein Binding; Pyridines; Rats; Spectrophotometry; Time Factors | 1972 |
The metabolism of the naturally occurring hepatocarcinogen safrole to 1'-hydroxysafrole and the electrophilic reactivity of 1'-acetoxysafrole.
Topics: Acetates; Acetone; Acetylation; Allyl Compounds; Anhydrides; Animals; Bromides; Carbon Isotopes; Carcinogens; Chromatography, Thin Layer; Cricetinae; Dioxoles; Electrochemistry; Glucuronidase; Guanine Nucleotides; Guinea Pigs; Hydroxylation; Injections, Intraperitoneal; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Methionine; Methods; Nucleosides; Phenobarbital; Rats; Succinimides; Tritium; Ultraviolet Rays | 1973 |
Carbohydrate metabolism in brain during convulsions and its modification by phenobarbitone.
Topics: Acetone; Animals; Brain; Carbohydrate Metabolism; Citrates; Electric Stimulation; Fumarates; Ketoglutaric Acids; Malates; Male; Mice; Mice, Inbred ICR; Oxaloacetates; Phenobarbital; Pyruvates; Seizures; Succinates | 1973 |
Aryl hydrocarbon (benzo(a)pyrene) hydroxylase in microsomes from rat tissues: differential inhibition and stimulation by benzoflavones and organic solvents.
Topics: 1-Propanol; Acetone; Alcohols; Animals; Benz(a)Anthracenes; Benzopyrenes; Cells, Cultured; Cricetinae; Dimethyl Sulfoxide; Embryo, Mammalian; Enzyme Induction; Ethanol; Flavonoids; In Vitro Techniques; Kidney; Lung; Male; Methanol; Methylcholanthrene; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; Organ Specificity; Phenobarbital; Rats; Skin | 1971 |
Some effects of ethanol on the toxicity and distribution of barbiturates in rats.
Topics: Acetaldehyde; Acetone; Amobarbital; Animals; Barbiturates; Brain Chemistry; Drug Synergism; Ethanol; Male; Pentobarbital; Phenobarbital; Rats; Reflex; Sleep; Thiopental | 1970 |
The mechanism of the oxidation of d-amphetamine by rabbit liver oxygenase. Oxygen-18 studies.
Topics: Acetone; Animals; Chromatography, Gas; Dextroamphetamine; Hydrolysis; Male; Microsomes, Liver; Models, Biological; Oximes; Oxygen Consumption; Oxygen Isotopes; Oxygenases; Phenobarbital; Rabbits; Sulfuric Acids | 1971 |
The migration of deuterium during aryl hydroxylation. II. Effect of induction of microsomal hydroxylases with phenobarbital or polycyclic aromatic hydrocarbons.
Topics: Acetanilides; Acetone; Animals; Benzopyrenes; Cats; Cricetinae; Depression, Chemical; Deuterium; Enzyme Induction; Female; Genetics; Guinea Pigs; Hydrogen-Ion Concentration; Liver; Male; Methylcholanthrene; Mice; Microsomes; Mixed Function Oxygenases; Phenobarbital; Rabbits; Rats; Sex Factors; Species Specificity; Stimulation, Chemical; Tritium | 1969 |
The effectiveness of N-acetylcysteine in isolated hepatocytes, against the toxicity of paracetamol, acrolein, and paraquat.
Topics: Acetaminophen; Acetone; Acetylcysteine; Acrolein; Aldehydes; Amino Acids; Animals; Cell Survival; Chemical and Drug Induced Liver Injury; Glutathione; Liver; Male; Maleates; Paraquat; Phenobarbital; Rats; Rats, Inbred Strains | 1984 |
Effect of acetone on the activation of acetaminophen.
Topics: Acetaminophen; Acetone; Animals; Biotransformation; Drug Interactions; Glutathione; Kinetics; Liver; Male; Microsomes, Liver; NAD; Phenobarbital; Rats | 1980 |
Enhancement by cyanide of aniline p-hydroxylation activity in rat liver microsomes.
Topics: 2,2'-Dipyridyl; Acetone; Aniline Hydroxylase; Animals; Aryl Hydrocarbon Hydroxylases; Cyanides; Cytochrome P-450 Enzyme System; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; NADP; Oxygen; Phenobarbital; Potassium Cyanide; Rats | 1980 |
Intestinal metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in rats: Sex difference, inducibility and inhibition by phenethylisothiocyanate.
Topics: Acetone; Animals; Carcinogens; Ethanol; Female; Intestinal Mucosa; Isothiocyanates; Male; Nitrosamines; Phenobarbital; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Sex Factors; Species Specificity | 1995 |
Relationship between cytochrome P450 2E1 and acetone catabolism in rats as studied with diallyl sulfide as an inhibitor.
Topics: Acetone; Aldehyde Dehydrogenase; Allyl Compounds; Animals; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Liver; Male; Oxidoreductases, N-Demethylating; Phenobarbital; Rats; Rats, Sprague-Dawley; Sulfides; Sulfones; Sulfoxides | 1994 |
Comparative metabolism and disposition of acrylonitrile and methacrylonitrile in rats.
Topics: Acetone; Acrylonitrile; Administration, Oral; Animals; Chromatography, High Pressure Liquid; Digestive System; Intestinal Absorption; Lung; Male; Methacrylates; Nitriles; Phenobarbital; Proadifen; Rats; Rats, Inbred F344; Structure-Activity Relationship; Tissue Distribution | 1994 |
Influence of inducers and inhibitors of cytochrome P450 on the hepatotoxicity of hydrazine in vivo.
Topics: Acetone; Adenosine Triphosphate; Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Glutathione; Hydrazines; Isoniazid; Liver; Male; Phenobarbital; Piperonyl Butoxide; Rats; Rats, Sprague-Dawley; Triglycerides | 1994 |
Effects of D-limonene on hepatic microsomal monooxygenase activity and paracetamol-induced glutathione depletion in mouse.
Topics: Acetaminophen; Acetone; Animals; Antineoplastic Agents; Benzoflavones; beta-Naphthoflavone; Cyclohexenes; Cytochrome P-450 Enzyme System; Glutathione; Limonene; Male; Mice; Microsomes, Liver; Oxygenases; Phenobarbital; Terpenes | 1993 |
Interaction of caffeine with acetaminophen. 1. Correlation of the effect of caffeine on acetaminophen hepatotoxicity and acetaminophen bioactivation following treatment of mice with various cytochrome P450 inducing agents.
Topics: Acetaminophen; Acetone; Aminopyrine N-Demethylase; Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Benzoquinones; beta-Naphthoflavone; Biotransformation; Caffeine; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Drug Interactions; Enzyme Activation; Female; Imines; Isoenzymes; Kinetics; Liver Diseases; Mice; Microsomes, Liver; Oxidoreductases, N-Demethylating; Phenobarbital | 1993 |
Toluene metabolism in isolated rat hepatocytes: effects of in vivo pretreatment with acetone and phenobarbital.
Topics: Acetone; Animals; Benzaldehydes; Benzoates; Benzoic Acid; Benzyl Alcohol; Benzyl Alcohols; Binding, Competitive; Cell Survival; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Glycine; Hippurates; Isoenzymes; Kinetics; Liver; Male; Oxidation-Reduction; Phenobarbital; Rats; Rats, Wistar; Toluene | 1993 |
Involvement of CYP2E in 8-hydroxylation of theophylline in mouse hepatic microsomes-difference from its N-demethylations.
Topics: Acetone; Aminoacetonitrile; Aminopyrine; Animals; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fomepizole; Hydroxylation; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Nitrophenols; Oxazines; Phenobarbital; Pregnenolone Carbonitrile; Pyrazoles; Theophylline | 1996 |
Cytochrome P-450 and free radical generation in rat liver microsomes under the influence of prostaglandin E1.
Topics: Acetone; Alprostadil; Animals; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP2E1; Down-Regulation; Ethanol; Free Radicals; Hydrogen Peroxide; Luminescent Measurements; Male; Microsomes, Liver; NADH, NADPH Oxidoreductases; NADP; NADPH Oxidases; Phenobarbital; Rats; Rats, Inbred Strains; Starvation; Superoxide Dismutase | 1996 |
Islet antioxidant and second phase enzyme levels following CYP1A, CYP2E, CYP2B and CYP4A induction.
Topics: Acetone; Animals; Antioxidants; Catalase; Clofibrate; Cytochrome P-450 Enzyme System; Enzyme Induction; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Islets of Langerhans; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Wistar; Superoxide Dismutase | 1997 |
Characterization of 1-hydroxypyrene as a novel marker substrate of 3-methylcholanthrene-inducible phenol UDP-glucuronosyltransferase(s).
Topics: Acetone; Animals; Carcinogens; Chromatography, High Pressure Liquid; Creosote; Enzyme Induction; Enzyme Inhibitors; Glucuronates; Glucuronosyltransferase; Magnetic Resonance Spectroscopy; Male; Methylcholanthrene; Methylenebis(chloroaniline); Microsomes, Liver; Mutagens; Phenobarbital; Polychlorinated Biphenyls; Pyrazoles; Pyrenes; Rats; Rats, Wistar; Substrate Specificity | 1997 |
The role of different cytochrome P450 isoforms in in vitro chloroform metabolism.
Topics: Acetone; Animals; Aryl Hydrocarbon Hydroxylases; beta-Naphthoflavone; Biotransformation; Chloroform; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Dexamethasone; Drug Synergism; Enzyme Induction; Isoenzymes; Male; Microsomes, Liver; Phenobarbital; Pyrazoles; Rats; Rats, Sprague-Dawley; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases | 1996 |
Comparison and in vivo relevance of two different in vitro head space metabolic systems: liver S9 and liver slices.
Topics: Acetone; Animals; Benzoates; Benzoic Acid; Biotransformation; Chelating Agents; Ditiocarb; Hexanes; Hexanols; Hexanones; Hippurates; Hypnotics and Sedatives; In Vitro Techniques; Liver; Male; Phenobarbital; Rats; Rats, Sprague-Dawley; Solvents; Toluene | 1997 |
Cytochrome P450-dependent desaturation of lauric acid: isoform selectivity and mechanism of formation of 11-dodecenoic acid.
Topics: Acetone; Animals; Aroclors; Aryl Hydrocarbon Hydroxylases; Carcinogens; Catalysis; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; Enzyme Induction; Fatty Acids, Monounsaturated; Gas Chromatography-Mass Spectrometry; Isoenzymes; Lauric Acids; Microsomes, Liver; NADP; Phenobarbital; Rabbits; Rifampin; Stereoisomerism | 1998 |
Minimal effects of acrylonitrile on pulmonary and hepatic cell injury enzymes in rats with induced cytochrome P450.
Topics: Acetone; Acrylonitrile; Animals; beta-Naphthoflavone; Bronchoalveolar Lavage Fluid; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme Inhibitors; Ethanol; gamma-Glutamyltransferase; Isoenzymes; L-Iditol 2-Dehydrogenase; L-Lactate Dehydrogenase; Liver; Lung; Male; Phenobarbital; Pyridines; Rats; Rats, Sprague-Dawley | 1998 |
Cytochrome P450-dependent monooxygenase activities and their inducibility by classic P450 inducers in the liver, kidney, and nasal mucosa of male adult ring-necked pheasants.
Topics: Acetone; Animals; beta-Naphthoflavone; Birds; Clofibrate; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Kidney; Microsomes, Liver; Nasal Mucosa; Phenobarbital | 2000 |
Induction of P450 monooxygenases in the German cockroach, Blattella germanica L.
Topics: Acetone; Animals; Benzene Derivatives; beta-Naphthoflavone; Blattellidae; Cytochrome P-450 Enzyme System; Cytochromes b5; Enzyme Induction; Ethanol; Isoenzymes; Male; Methylcholanthrene; Mixed Function Oxygenases; Phenobarbital; RNA, Messenger | 2003 |
The influence of morphine and phenobarbital on the blood content of acetone-bodies in normal rabbits.
Topics: Acetone; Animals; Barbiturates; Ketone Bodies; Lagomorpha; Leadership; Morphine; Phenobarbital; Rabbits | 1952 |
Case 13-2019: A 54-Year-Old Man with Alcohol Withdrawal and Altered Mental Status.
Topics: 2-Propanol; Acetone; Acid-Base Equilibrium; Acidosis; Alcohol Withdrawal Delirium; Alcoholism; Diagnosis, Differential; Ethanol; Hand Sanitizers; Humans; Ill-Housed Persons; Male; Middle Aged; Phenobarbital; Poisoning; Radiography, Abdominal; Tachycardia; Tomography, X-Ray Computed | 2019 |