Compounds > acetone

acetone and metyrapone

acetone has been researched along with metyrapone in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19909 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ernster, L; Gustafsson, JA; Hrycay, EG; Ingelman-Sundberg, M1
Beckett, AH; Gorrod, JW; Temple, DJ1
Kamataki, T; Kitada, M; Kitagawa, H1
Bridges, JW; McPherson, FJ; Parke, DV1
Freeman, JJ; Hayes, EP1
Kogut, MD; Roe, TF1
Ikeda, M; Imamura, T; Otsuji, H1
Anders, MW1
Bryson, MJ; Dutcher, JS; Sweat, ML; Young, RB1

Reviews

1 review(s) available for acetone and metyrapone

ArticleYear
Enhancement and inhibition of drug metabolism.
    Annual review of pharmacology, 1971, Volume: 11

    Topics: Acetone; Animals; Drug Antagonism; Drug Interactions; Enzyme Inhibitors; Humans; Kinetics; Metyrapone; Microsomes, Liver; Nitriles; Oxidoreductases; Pharmaceutical Preparations; Proadifen; Pyridines; Rabbits; Rats

1971

Other Studies

8 other study(ies) available for acetone and metyrapone

ArticleYear
The involvement of cytochrome P-450 in hepatic microsomal steroid hydroxylation reactions supported by sodium periodate, sodium chlorite, and organic hydroperoxides.
    European journal of biochemistry, 1976, Jan-02, Volume: 61, Issue:1

    Topics: Acetone; Amines; Androstenedione; Aniline Compounds; Animals; Chlorine; Cytochrome P-450 Enzyme System; Estradiol; Kinetics; Male; Metyrapone; Microsomes, Liver; Periodic Acid; Peroxides; Progesterone; Rats; Spectrophotometry; Steroid Hydroxylases; Testosterone

1976
The differentiation of N-oxidation and N-dealkylation of N-ethyl-N-methylaniline by rabbit liver microsomes as distinct metabolic routes.
    Xenobiotica; the fate of foreign compounds in biological systems, 1975, Volume: 5, Issue:8

    Topics: 2,2'-Dipyridyl; Acetone; Aniline Compounds; Animals; Chloromercuribenzoates; Cysteamine; Cytochrome P-450 Enzyme System; Dealkylation; Dithiothreitol; Ethylmaleimide; Kinetics; Liver; Male; Metyrapone; Microsomes, Liver; NADP; Oxidoreductases; Proadifen; Rats; Subcellular Fractions

1975
Enhancement in vivo of drug oxidations following administration of benzphetamine, acetone, metyrapone and dimethylsulfoxide.
    Japanese journal of pharmacology, 1978, Volume: 28, Issue:2

    Topics: Acetone; Aniline Compounds; Aniline Hydroxylase; Animals; Benzphetamine; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Ethylmorphine; Male; Metyrapone; Microsomes, Liver; Oxidation-Reduction; Phenacetin; Phenethylamines; Rats; Stimulation, Chemical; Sulfoxides

1978
The effects of benzopyrene and safrole on biphenyl 2-hydroxylase and other drug-metabolizing enzymes.
    The Biochemical journal, 1976, Mar-15, Volume: 154, Issue:3

    Topics: Acetone; Aniline Hydroxylase; Animals; Benzopyrene Hydroxylase; Benzopyrenes; Catechol Oxidase; Cricetinae; Cytochromes; Dactinomycin; Dioxoles; Male; Methylcholanthrene; Metyrapone; Mice; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Nikethamide; Phenobarbital; Rats; Safrole

1976
Microsomal metabolism of acetonitrile to cyanide. Effects of acetone and other compounds.
    Biochemical pharmacology, 1988, Mar-15, Volume: 37, Issue:6

    Topics: Acetone; Acetonitriles; Aniline Compounds; Animals; Carbon Monoxide; Cyanides; Cytochrome P-450 Enzyme System; Dimethyl Sulfoxide; Ethanol; Female; Metyrapone; Microsomes, Liver; NAD; Proadifen; Proteins; Rats; Rats, Inbred Strains; Time Factors

1988
Hypopituitarism and ketotic hypoglycemia.
    American journal of diseases of children (1960), 1971, Volume: 121, Issue:4

    Topics: Acetone; Acidosis; Arginine; Body Height; Body Weight; Child; Fatty Acids, Nonesterified; Female; Glucose Tolerance Test; Growth; Growth Hormone; Humans; Hypoglycemia; Hypopituitarism; Insulin; Iodine Isotopes; Metyrapone; Pituitary-Adrenal Function Tests; Prednisone; Seizures; Thyroid Function Tests; Thyroid Hormones

1971
Comparative studies on aniline hydroxylation and p-nitrotoluene hydroxylation by the liver.
    Japanese journal of pharmacology, 1972, Volume: 22, Issue:4

    Topics: Acetamides; Acetone; Aniline Compounds; Animals; Biotransformation; Cricetinae; Depression, Chemical; Guinea Pigs; Hydroxylation; Kinetics; Liver; Methylcholanthrene; Metyrapone; Mice; Phenobarbital; Pyridines; Rabbits; Rats; Sex Factors; Stimulation, Chemical; Toluene

1972
Adrenal gland steroid C-21 cytochrome P-450 reductase.
    Biochemistry, 1969, Volume: 8, Issue:12

    Topics: Acetone; Adrenal Glands; Animals; Carbon Isotopes; Cattle; Cytochromes; Electron Transport; Flavins; Methods; Metyrapone; Microsomes; Mitochondria; Models, Biological; Models, Chemical; Oxidoreductases; Progesterone; Proteins; Steroids

1969