acetone has been researched along with dichloroacetic acid in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 5 (45.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dunn, WJ; Grigoras, S; Koehler, MG | 1 |
| Caron, G; Ermondi, G | 1 |
| Anders, MW; Baggs, RB; Board, PG; Krenitsky, DM; Lantum, HB | 1 |
| Anders, MW; Board, PG; Lantum, HB | 1 |
| Dixit, V; Guo, X; Henderson, GN; James, MO; Liu, H; Shroads, AL; Stacpoole, PW | 1 |
| Henderson, GN; Jia, M; Liu, H; Stacpoole, PW; Zolodz, MD | 1 |
| Bullock, JR; Coats, BS; Gong, Y; Johnson, JA; Kurtz, TL; Langaee, T; Ostrov, DA; Shroads, AL; Stacpoole, PW; Wagner, DA; Weithorn, D | 1 |
| Abdelmalak, MM; Daigle, AD; James, MO; Maisenbacher, HW; Mincey, BD; Samper, IS; Shroads, AL; Stacpoole, PW; Zhong, G | 1 |
| Coats, BS; Dunbar, EM; Forder, JR; Langaee, T; Lew, A; Shroads, AL; Shuster, JJ; Stacpoole, PW; Wagner, DA | 1 |
| Coats, BS; Langaee, T; McDonough, CW; Shroads, AL; Stacpoole, PW | 1 |
| Coats, BS; Langaee, T; Shroads, AL; Shuster, JJ; Stacpoole, PW | 1 |
3 trial(s) available for acetone and dichloroacetic acid
| Article | Year |
|---|---|
Phase 1 trial of dichloroacetate (DCA) in adults with recurrent malignant brain tumors.
Topics: Acetone; Adult; Aged; Alanine Transaminase; Antineoplastic Agents; Aspartate Aminotransferases; Brain Neoplasms; Breath Tests; Dichloroacetic Acid; Female; Glutathione Transferase; Haplotypes; Humans; Male; Maleates; Middle Aged; Pyruvic Acid | 2014 |
Haplotype variations in glutathione transferase zeta 1 influence the kinetics and dynamics of chronic dichloroacetate in children.
Topics: Acetone; Adolescent; Adult; Aminolevulinic Acid; Child; Child, Preschool; Dichloroacetic Acid; Double-Blind Method; Female; Genetic Diseases, Inborn; Glutathione Transferase; Haplotypes; Humans; Infant; Kinetics; Male; Maleates; Mitochondrial Diseases; Polymorphism, Single Nucleotide; Tyrosine; Young Adult | 2015 |
Chloral hydrate, through biotransformation to dichloroacetate, inhibits maleylacetoacetate isomerase and tyrosine catabolism in humans.
Topics: Acetone; Adult; Biomarkers; Chloral Hydrate; cis-trans-Isomerases; Dichloroacetic Acid; Female; Glutathione Transferase; Healthy Volunteers; Humans; Hypnotics and Sedatives; Male; Maleates; Tyrosine; Young Adult | 2015 |
8 other study(ies) available for acetone and dichloroacetic acid
| Article | Year |
|---|---|
The role of solvent-accessible surface area in determining partition coefficients.
Topics: Diffusion; Solubility; Solvents; Structure-Activity Relationship | 1987 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Immunohistochemical localization and activity of glutathione transferase zeta (GSTZ1-1) in rat tissues.
Topics: Acetates; Acetone; Animals; Dichloroacetic Acid; Environmental Pollutants; Glutathione Transferase; Immunoblotting; Immunohistochemistry; Male; Maleates; Organ Specificity; Rats; Rats, Inbred F344; Subcellular Fractions | 2002 |
Kinetics of the biotransformation of maleylacetone and chlorofluoroacetic acid by polymorphic variants of human glutathione transferase zeta (hGSTZ1-1).
Topics: Acetates; Acetone; Biotransformation; cis-trans-Isomerases; Dichloroacetic Acid; Enzyme Inhibitors; Glutathione Transferase; Humans; Hydrogen-Ion Concentration; Kinetics; Maleates; Polymorphism, Single Nucleotide; Recombinant Proteins; Substrate Specificity | 2002 |
Inhibition and recovery of rat hepatic glutathione S-transferase zeta and alteration of tyrosine metabolism following dichloroacetate exposure and withdrawal.
Topics: Acetone; Administration, Oral; Aging; Animals; Blotting, Western; Body Weight; Dichloroacetic Acid; Dose-Response Relationship, Drug; Drinking; Drug Administration Schedule; Glutathione Transferase; Humans; Liver; Male; Maleates; Organ Size; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine | 2006 |
A GC-MS/MS method for the quantitative analysis of low levels of the tyrosine metabolites maleylacetone, succinylacetone, and the tyrosine metabolism inhibitor dichloroacetate in biological fluids and tissues.
Topics: Acetone; Animals; Blotting, Western; Dichloroacetic Acid; Gas Chromatography-Mass Spectrometry; Heptanoates; Humans; Liver; Male; Maleates; Rats; Sensitivity and Specificity; Tyrosine | 2006 |
Human polymorphisms in the glutathione transferase zeta 1/maleylacetoacetate isomerase gene influence the toxicokinetics of dichloroacetate.
Topics: Acetone; Adult; Amino Acid Substitution; Dichloroacetic Acid; Environmental Pollutants; Enzyme Stability; Female; Florida; Genetic Association Studies; Glutathione Transferase; Half-Life; Humans; Male; Maleates; Middle Aged; Models, Molecular; Mutation; Polymorphism, Single Nucleotide; Protein Conformation; Tyrosine; Young Adult | 2012 |
Pharmacokinetics of oral dichloroacetate in dogs.
Topics: Acetone; Analysis of Variance; Animals; Area Under Curve; Blotting, Western; cis-trans-Isomerases; Dichloroacetic Acid; Dogs; Glutathione Transferase; Half-Life; Injections, Intravenous; Male; Maleates; Tyrosine | 2013 |