acetone and 1-phenyl-2-propanone

acetone has been researched along with 1-phenyl-2-propanone in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19907 (16.67)18.7374
1990's0 (0.00)18.2507
2000's8 (19.05)29.6817
2010's22 (52.38)24.3611
2020's5 (11.90)2.80

Authors

AuthorsStudies
Coutts, RT; Jones, GR; Townsend, RE1
Green, CE; LeValley, SE; Tyson, CA1
Frank, RS1
Sinnema, A; Verweij, AM1
Blume, H1
Coutts, RT; Jones, GR; Prelusky, DB1
Dal Cason, TA1
Janusz, A; Kirkbride, KP; Megharaj, M; Naidu, R; Perkins, MV; Scott, TL1
FREEMAN, SK1
Fortin, R; Fraaije, MW; Heidekamp, AJ; Janssen, DB; Kamerbeek, NM1
Alfieri, A; Fraaije, MW; Malito, E; Mattevi, A1
Lavrich, RJ; Plusquellic, DF; Suenram, RD; Tubergen, MJ1
Musa, MM; Phillips, RS; Vieille, C; Zeikus, JG; Ziegelmann-Fjeld, KI1
Dahlenburg, R; Holdermann, T; Schneiders, S1
Acevedo, JP; Reetz, MT; Wu, S1
Scriba, GK; Sungthong, B; Wongwan, S1
Bauer, EB; Rath, NP; Shejwalkar, P1
de Gonzalo, G; Dudek, HM; Fraaije, MW; Gotor, V; Rodríguez, C; Torres Pazmiño, DE1
Dudek, D; Krawczyk, W; Kunda, T; Perkowska, I1
Dudek, HM; Fraaije, MW; Martinoli, C; Mattevi, A; Orru, R; Royant, A; Torres Pazmiño, DE; Weik, M1
de Gonzalo, G; Dudek, HM; Fraaije, MW; Pazmiño, DE; Rychlewski, L; Stepniak, P; Wyrwicz, LS1
Kavanagh, P; McDermott, SD; O'Brien, J; Power, JD1
de Gonzalo, G; Gotor, V; Rioz-Martínez, A; Rodríguez, C1
de Gonzalo, G; Fraaije, MW; van Beek, HL1
Badawi, HM; Förner, W1
Fraaije, MW; Franceschini, S; Martinoli, C; Mattevi, A; Pennetta, A; van Beek, HL1
Dudek, HM; Duetz, WA; Fraaije, MW; van Bloois, E1
Dennig, A; Dudek, HM; Fink, MJ; Fraaije, MW; Mihovilovic, MD; Schwaneberg, U; Shivange, AV1
Cantillo, D; de Frutos, O; Kappe, CO; Mateos, C; Rincon, JA1
Dunn, RF; Figus, M; Zacuto, MJ1
Acevedo, JP; Parra, LP; Reetz, MT1
Brown, JL; Guest, EM; Hays, PA; Lurie, IS; McConnell, JB; Miller, EE; Phillips, MZ; Toske, SG; Tuten, JM; Vazquez, ER1
Barry, M; Brandt, SD; Dowling, G; Kavanagh, P; McLaughlin, G; O'Brien, J; Power, JD; Talbot, B; Twamley, B1
Doughty, D; Johnston, MR; Painter, B; Pigou, PE1
Ferroni, FM; Opperman, DJ; Smit, MS; Tolmie, C1
Barry, M; Brandt, SD; Dowling, G; Kavanagh, P; McLaughlin, G; Power, JD1
Carvalho, ATP; de Abreu, M; Dourado, DFAR; Ferguson, LJ; Huang, M; Moody, TS; Quinn, DJ; Skvortsov, T1
Atroshenko, DL; Kleymenov, SY; Martysuk, UA; Parshin, PD; Pometun, AA; Pometun, EV; Savin, SS; Tishkov, VI1
Beloglazova, N; De Rycke, E; De Saeger, S; Dubruel, P; Jaworowicz, M; Trynda, A1
Jolliffe, KA; Lansdown, K; Salouros, H1
Iwata, YT; Kanamori, T; Kuwayama, K; Okada, Y; Segawa, H; Tsujikawa, K; Yamamuro, T1
Lin, J; Su, B; Wang, L; Wang, S; Xu, L; Xu, X; Zhang, Y1

Reviews

1 review(s) available for acetone and 1-phenyl-2-propanone

ArticleYear
Impurities in illicit amphetamine: review.
    Bulletin on narcotics, 1981, Volume: 33, Issue:3

    Topics: Acetone; Alkenes; Amphetamines; Chemical Phenomena; Chemistry; Chromatography, Gas; Chromatography, Thin Layer; Drug Contamination; Illicit Drugs; Mass Spectrometry; Nitro Compounds; Oximes; Pharmaceutical Preparations; Propiophenones

1981

Other Studies

41 other study(ies) available for acetone and 1-phenyl-2-propanone

ArticleYear
Species differences in the in vitro metabolic reduction of the amphetamine metabolite, 1-phenyl-2-propanone.
    The Journal of pharmacy and pharmacology, 1978, Volume: 30, Issue:7

    Topics: Acetone; Animals; Guinea Pigs; In Vitro Techniques; Liver; Male; Oxidation-Reduction; Propiophenones; Rabbits; Rats; Species Specificity

1978
Comparison of amphetamine metabolism using isolated hepatocytes from five species including human.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 237, Issue:3

    Topics: Acetone; Adult; Amphetamine; Animals; Benzoates; Benzoic Acid; Dogs; Female; Hippurates; Humans; Hydroxylation; In Vitro Techniques; Liver; Male; p-Hydroxyamphetamine; Rabbits; Rats; Rats, Inbred Strains; Saimiri; Species Specificity

1986
The clandestine drug laboratory situation in the United States.
    Journal of forensic sciences, 1983, Volume: 28, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Acetone; Amphetamine; Drug and Narcotic Control; Humans; Illicit Drugs; Methamphetamine; Methaqualone; Pharmaceutical Preparations; Phencyclidine; Substance-Related Disorders; United States

1983
[Biotransformation of amphetamine derivatives by rat liver mitochondria/2nd communication; Oxidative deamination of amphetamine and reduction of phenylacetone].
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:6

    Topics: Acetone; Amphetamine; Animals; Biotransformation; Deamination; In Vitro Techniques; Ketone Oxidoreductases; Microsomes, Liver; Mitochondria, Liver; Monoamine Oxidase; Oxidation-Reduction; Propiophenones; Rats

1981
The effects of cofactor and species differences on the in vitro metabolism of propiophenone and phenylacetone.
    Canadian journal of physiology and pharmacology, 1981, Volume: 59, Issue:2

    Topics: Acetone; Animals; Hydroxylation; In Vitro Techniques; Liver; NAD; NADP; Oxidation-Reduction; Propiophenones; Rabbits; Rats; Species Specificity

1981
A re-examination of the mono-methoxy positional ring isomers of amphetamine, methamphetamine and phenyl-2-propanone.
    Forensic science international, 2001, Jun-15, Volume: 119, Issue:2

    Topics: Acetone; Amphetamine; Amphetamines; Cause of Death; Chemistry, Pharmaceutical; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Isomerism; Magnetic Resonance Spectroscopy; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Spectrophotometry, Infrared; Substance Abuse Detection; United States

2001
Microbial degradation of illicit drugs, their precursors, and manufacturing by-products: implications for clandestine drug laboratory investigation and environmental assessment.
    Forensic science international, 2003, Jun-24, Volume: 134, Issue:1

    Topics: 2-Propanol; Acetone; Biodegradation, Environmental; Central Nervous System Stimulants; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Magnetic Resonance Spectroscopy; Methamphetamine; Soil; Soil Microbiology

2003
The spectrophotometric determination of phenylacetone in amphetamine.
    Journal of the American Pharmaceutical Association. American Pharmaceutical Association, 1953, Volume: 42, Issue:10

    Topics: Acetone; Amphetamine; Amphetamines; Humans; Spectrophotometry; Spectrum Analysis

1953
The prodrug activator EtaA from Mycobacterium tuberculosis is a Baeyer-Villiger monooxygenase.
    The Journal of biological chemistry, 2004, Jan-30, Volume: 279, Issue:5

    Topics: Acetone; Amino Acid Motifs; Antitubercular Agents; Bacterial Proteins; Catalysis; Dose-Response Relationship, Drug; Esters; Ethionamide; Ketones; Kinetics; Lactones; Models, Chemical; Mycobacterium tuberculosis; Oxidation-Reduction; Oxygen; Oxygenases; Prodrugs; Protein Binding; Recombinant Proteins; Serum Albumin; Spectrophotometry; Time Factors

2004
Crystal structure of a Baeyer-Villiger monooxygenase.
    Proceedings of the National Academy of Sciences of the United States of America, 2004, Sep-07, Volume: 101, Issue:36

    Topics: Acetone; Actinomycetales; Amino Acid Sequence; Binding Sites; Catalysis; Flavin-Adenine Dinucleotide; Mixed Function Oxygenases; Models, Molecular; Molecular Sequence Data; NADP; Protein Conformation

2004
Rotational spectra and conformational structures of 1-phenyl-2-propanol, methamphetamine, and 1-phenyl-2-propanone.
    The journal of physical chemistry. A, 2006, Dec-14, Volume: 110, Issue:49

    Topics: Acetone; Methamphetamine; Molecular Conformation; Phenylethyl Alcohol; Spectrum Analysis

2006
A Thermoanaerobacter ethanolicus secondary alcohol dehydrogenase mutant derivative highly active and stereoselective on phenylacetone and benzylacetone.
    Protein engineering, design & selection : PEDS, 2007, Volume: 20, Issue:2

    Topics: Acetone; Alcohol Oxidoreductases; Benzyl Compounds; Binding Sites; Catalysis; Molecular Structure; Mutation; Oxidation-Reduction; Phenylethyl Alcohol; Stereoisomerism; Substrate Specificity; Thermoanaerobacter

2007
Comparative analysis of 1-phenyl-2-propanone (P2P), an amphetamine-type stimulant precursor, using stable isotope ratio mass spectrometry: presented in part as a poster at the 2nd meeting of the Joint European Stable Isotope User Meeting (JESIUM), Giens,
    Science & justice : journal of the Forensic Science Society, 2009, Volume: 49, Issue:2

    Topics: Acetone; Amphetamines; Carbon Isotopes; Forensic Sciences; Gas Chromatography-Mass Spectrometry; Germany; Nitrogen Isotopes; Oxygen

2009
Induced allostery in the directed evolution of an enantioselective Baeyer-Villiger monooxygenase.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Feb-16, Volume: 107, Issue:7

    Topics: Acetone; Allosteric Regulation; Directed Molecular Evolution; Mixed Function Oxygenases; Models, Molecular; Molecular Dynamics Simulation; Molecular Structure; Mutagenesis; Temperature

2010
CE assay for simultaneous determination of charged and neutral impurities in dexamphetamine sulfate using a dual CD system.
    Electrophoresis, 2010, Volume: 31, Issue:9

    Topics: Acetone; Amphetamine; beta-Cyclodextrins; Calibration; Dextroamphetamine; Drug Contamination; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Linear Models; Oximes; Phenylpropanolamine; Reproducibility of Results; Sensitivity and Specificity; Stereoisomerism

2010
New chiral phosphoramidite complexes of iron as catalytic precursors in the oxidation of activated methylene groups.
    Molecules (Basel, Switzerland), 2010, Apr-12, Volume: 15, Issue:4

    Topics: Acetone; Catalysis; Coordination Complexes; Iron; Organophosphorus Compounds; Oxidation-Reduction

2010
Investigating the coenzyme specificity of phenylacetone monooxygenase from Thermobifida fusca.
    Applied microbiology and biotechnology, 2010, Volume: 88, Issue:5

    Topics: Acetone; Actinomycetales; Amino Acid Sequence; Base Sequence; Coenzymes; Gene Expression; Genetic Engineering; Kinetics; Metabolic Networks and Pathways; Mixed Function Oxygenases; Models, Molecular; Mutagenesis, Site-Directed; NADP; Oxidation-Reduction; Protein Binding; Protein Conformation; Recombinant Proteins; Sequence Alignment; Sequence Homology; Substrate Specificity

2010
Impurity profiling/comparative analyses of samples of 1-phenyl-2-propanone.
    Bulletin on narcotics, 2005, Volume: 57, Issue:1-2

    Topics: Acetone; Amphetamine; Cluster Analysis; Commerce; Databases as Topic; Drug and Narcotic Control; Drug Compounding; Drug Contamination; Forensic Sciences; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Laboratories; Poland; Police

2005
Snapshots of enzymatic Baeyer-Villiger catalysis: oxygen activation and intermediate stabilization.
    The Journal of biological chemistry, 2011, Aug-19, Volume: 286, Issue:33

    Topics: Acetone; Actinomycetales; Bacterial Proteins; Catalysis; Mixed Function Oxygenases; Models, Chemical; NADP; Oxygen

2011
Mapping the substrate binding site of phenylacetone monooxygenase from Thermobifida fusca by mutational analysis.
    Applied and environmental microbiology, 2011, Aug-15, Volume: 77, Issue:16

    Topics: Acetone; Actinomycetales; Algorithms; Amino Acid Sequence; Binding Sites; DNA Mutational Analysis; Enzyme Stability; Escherichia coli; Genes, Bacterial; Mixed Function Oxygenases; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oxidation-Reduction; Oxygenases; Protein Binding; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity

2011
The analysis of substituted cathinones. Part 2: an investigation into the phenylacetone based isomers of 4-methylmethcathinone and N-ethylcathinone.
    Forensic science international, 2011, Oct-10, Volume: 212, Issue:1-3

    Topics: Acetone; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Isomerism; Magnetic Resonance Spectroscopy; Methamphetamine; Morpholines; Sampling Studies; Sensitivity and Specificity

2011
Improvement of the biocatalytic properties of one phenylacetone monooxygenase mutant in hydrophilic organic solvents.
    Enzyme and microbial technology, 2012, Jan-05, Volume: 50, Issue:1

    Topics: Acetone; Actinomycetales; Bacterial Proteins; Biocatalysis; Enzyme Stability; Hydrophobic and Hydrophilic Interactions; Ion Exchange Resins; Isomerism; Ketones; Kinetics; Mixed Function Oxygenases; Mutagenesis, Site-Directed; Mutant Proteins; Protein Engineering; Recombinant Proteins; Solvents; Substrate Specificity

2012
Blending Baeyer-Villiger monooxygenases: using a robust BVMO as a scaffold for creating chimeric enzymes with novel catalytic properties.
    Chemical communications (Cambridge, England), 2012, Apr-04, Volume: 48, Issue:27

    Topics: Acetone; Biocatalysis; Kinetics; Metagenome; Mixed Function Oxygenases; Models, Molecular; NADH, NADPH Oxidoreductases; Oxidation-Reduction; Oxygenases; Protein Engineering; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Fusion Proteins; Stereoisomerism; Substrate Specificity

2012
Analysis of the infrared and Raman spectra of the symmetrically substituted 1,3-diphenylurea and 1,3-diphenylacetone (dibenzyl ketone).
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2012, Volume: 95

    Topics: Acetone; Carbanilides; Molecular Conformation; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Thermodynamics; Urea

2012
Exploring the structural basis of substrate preferences in Baeyer-Villiger monooxygenases: insight from steroid monooxygenase.
    The Journal of biological chemistry, 2012, Jun-29, Volume: 287, Issue:27

    Topics: Acetone; Catalysis; Catalytic Domain; Crystallography, X-Ray; Escherichia coli; Evolution, Molecular; Hydroxyprogesterones; Mutagenesis, Site-Directed; NADP; Oxidation-Reduction; Oxygen; Protein Engineering; Protein Structure, Secondary; Protein Structure, Tertiary; Rhodococcus; Steroid Hydroxylases; Structure-Activity Relationship; Substrate Specificity

2012
A stepwise approach for the reproducible optimization of PAMO expression in Escherichia coli for whole-cell biocatalysis.
    BMC biotechnology, 2012, Jun-21, Volume: 12

    Topics: Acetone; Actinomycetales; Biocatalysis; Escherichia coli; Kinetics; Mixed Function Oxygenases; Recombinant Proteins; Substrate Specificity; Temperature; Time Factors

2012
Extending the substrate scope of a Baeyer-Villiger monooxygenase by multiple-site mutagenesis.
    Applied microbiology and biotechnology, 2014, Volume: 98, Issue:9

    Topics: Acetone; Genetic Testing; Ketones; Mixed Function Oxygenases; Mutagenesis; Substrate Specificity

2014
A scalable procedure for light-induced benzylic brominations in continuous flow.
    The Journal of organic chemistry, 2014, Jan-03, Volume: 79, Issue:1

    Topics: Acetone; Benzyl Compounds; Bromosuccinimide; Catalysis; Halogenation; Light; Molecular Structure; Photochemical Processes; Polytetrafluoroethylene

2014
One-step synthesis of 1-chloro-3-arylacetone derivatives from arylacetic acids.
    The Journal of organic chemistry, 2014, Sep-19, Volume: 79, Issue:18

    Topics: Acetone; Biological Products; Catalysis; Phenylacetates; Phenylpropionates; Stereoisomerism

2014
Directed evolution of phenylacetone monooxygenase as an active catalyst for the Baeyer-Villiger conversion of cyclohexanone to caprolactone.
    Biotechnology and bioengineering, 2015, Volume: 112, Issue:7

    Topics: Acetone; Biotransformation; Caproates; Cyclohexanones; Directed Molecular Evolution; Escherichia coli; Kinetics; Lactones; Mixed Function Oxygenases; Molecular Dynamics Simulation; Mutant Proteins; NADP

2015
Isolation and characterization of a newly identified impurity in methamphetamine synthesized via reductive amination of 1-phenyl-2-propanone (P2P) made from phenylacetic acid/lead (II) acetate.
    Drug testing and analysis, 2017, Volume: 9, Issue:3

    Topics: Acetone; Amination; Central Nervous System Stimulants; Drug Contamination; Illicit Drugs; Methamphetamine; Organometallic Compounds; Oxidation-Reduction; Phenylacetates

2017
Forensic analysis of P2P derived amphetamine synthesis impurities: identification and characterization of indene by-products.
    Drug testing and analysis, 2017, Volume: 9, Issue:3

    Topics: Acetone; Amphetamine; Central Nervous System Stimulants; Chromatography, Liquid; Crystallography, X-Ray; Drug Contamination; Gas Chromatography-Mass Spectrometry; Illicit Drugs; Indenes; Magnetic Resonance Spectroscopy; Models, Molecular; Styrenes

2017
The synthesis and investigation of impurities found in Clandestine Laboratories: Baeyer-Villiger Route Part I; Synthesis of P2P from benzaldehyde and methyl ethyl ketone.
    Forensic science international, 2016, Volume: 263

    Topics: Acetone; Benzaldehydes; Biocatalysis; Butanones; Central Nervous System Stimulants; Drug Contamination; Humans; Illicit Drugs; Methamphetamine; Oxygenases

2016
Structural and Catalytic Characterization of a Fungal Baeyer-Villiger Monooxygenase.
    PloS one, 2016, Volume: 11, Issue:7

    Topics: Acetone; Aspergillus flavus; Catalysis; Crystallization; Crystallography, X-Ray; Electrophoresis, Polyacrylamide Gel; Kinetics; Mixed Function Oxygenases; Protein Conformation; Substrate Specificity

2016
'APAAN in the neck' - A reflection on some novel impurities found in seized materials containing amphetamine in Ireland during routine forensic analysis.
    Drug testing and analysis, 2017, Volume: 9, Issue:7

    Topics: Acetone; Acetonitriles; Amphetamine; Central Nervous System Stimulants; Drug Contamination; Gas Chromatography-Mass Spectrometry; Hydrolysis; Illicit Drugs; Ireland; Pharmacy

2017
Spatial requirement for PAMO for transformation of non-native linear substrates.
    Physical chemistry chemical physics : PCCP, 2018, Jan-24, Volume: 20, Issue:4

    Topics: Acetone; Actinobacteria; Amino Acid Sequence; Binding Sites; Biocatalysis; Catalytic Domain; Ketones; Kinetics; Mixed Function Oxygenases; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Recombinant Proteins; Sequence Alignment; Substrate Specificity

2018
Effect of His
    Biochemistry. Biokhimiia, 2020, Volume: 85, Issue:5

    Topics: Acetone; Histidine; Kinetics; Mixed Function Oxygenases; Oligopeptides; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity; Thermobifida

2020
Capacitive sensing of an amphetamine drug precursor in aqueous samples: Application of novel molecularly imprinted polymers for benzyl methyl ketone detection.
    Biosensors & bioelectronics, 2021, Jan-15, Volume: 172

    Topics: Acetone; Amphetamine; Biosensing Techniques; Electrochemical Techniques; Molecular Imprinting; Molecularly Imprinted Polymers; Polymers; Prodrugs; Water

2021
Investigations into the stable isotope ratios of 1-phenyl-2-propanone.
    Drug testing and analysis, 2022, Volume: 14, Issue:3

    Topics: Acetone; Carbon Isotopes; Illicit Drugs; Methamphetamine; Nitrogen Isotopes

2022
Analysis of potential phenylacetone precursors (ethyl 3-oxo-2-phenylbutyrate, methyl 3-oxo-4-phenylbutyrate, and ethyl 3-oxo-4-phenylbutyrate) by gas chromatography/mass spectrometry and their conversion to phenylacetone.
    Drug testing and analysis, 2022, Volume: 14, Issue:3

    Topics: Acetone; Amphetamine; Gas Chromatography-Mass Spectrometry; Phenylbutyrates

2022
"Nonpolarity paving" in substrate tunnel of a Limnobacter sp. Phenylacetone monooxygenase for efficient single whole-cell synthesis of esomeprazole.
    Bioorganic chemistry, 2022, Volume: 125

    Topics: Acetone; Escherichia coli; Esomeprazole; Formate Dehydrogenases; Mixed Function Oxygenases; Oxidation-Reduction; Substrate Specificity

2022