acetogenins and hydroxide-ion

acetogenins has been researched along with hydroxide-ion* in 1 studies

Other Studies

1 other study(ies) available for acetogenins and hydroxide-ion

Article	Year
Synthesis and mitochondrial complex I inhibition of dihydroxy-cohibin A, non-THF annonaceous acetogenin analogue. Bioorganic & medicinal chemistry letters, 2004, Feb-09, Volume: 14, Issue:3 To elucidate the inhibitory action of acetogenins, we synthesized an acetogenin derivative which possesses tetraol in place of the tetrahydrofuran ring and examined its inhibitory activity against bovine heart mitochondrial complex I. Our results indicate that these hydroxy groups are an essential structural factor though it is not effective as bis-THF hydroxy groups combination. Topics: Acetogenins; Animals; Cattle; Electron Transport Complex I; Enzyme Inhibitors; Fatty Alcohols; Furans; Hydroxides; Lactones; Mitochondria, Heart; Molecular Structure; Structure-Activity Relationship; Submitochondrial Particles	2004

Article

Year

Synthesis and mitochondrial complex I inhibition of dihydroxy-cohibin A, non-THF annonaceous acetogenin analogue.

Bioorganic & medicinal chemistry letters, 2004, Feb-09, Volume: 14, Issue:3

To elucidate the inhibitory action of acetogenins, we synthesized an acetogenin derivative which possesses tetraol in place of the tetrahydrofuran ring and examined its inhibitory activity against bovine heart mitochondrial complex I. Our results indicate that these hydroxy groups are an essential structural factor though it is not effective as bis-THF hydroxy groups combination.

Topics: Acetogenins; Animals; Cattle; Electron Transport Complex I; Enzyme Inhibitors; Fatty Alcohols; Furans; Hydroxides; Lactones; Mitochondria, Heart; Molecular Structure; Structure-Activity Relationship; Submitochondrial Particles

2004