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acetaminophen glucuronide and acetaminophen sulfate ester

acetaminophen glucuronide has been researched along with acetaminophen sulfate ester in 56 studies

Research

Studies (56)

Timeframe	Studies, this research(%)	All Research%
pre-1990	11 (19.64)	18.7374
1990's	16 (28.57)	18.2507
2000's	16 (28.57)	29.6817
2010's	13 (23.21)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Prescott, LF	1
Edwards, G; Mansor, SM; Roberts, PJ; Ward, SA	1
Lunte, CE; Puckett, DL; Scott, DO; Sorenson, LR; Steele, KL	1
Klaassen, CD; Madhu, C	1
Goon, D; Klaassen, CD	1
Brouwer, KL; Jones, JA	1
Bhargava, VO; Hirate, J; Horikoshi, I; Zhu, CY	1
Nakamura, J; Podder, SK; Sasaki, H; Shibasaki, J	1
Comeau, AM; Ecobichon, DJ; Hidvegi, S; Varma, DR	1
Gee, D; Pannall, P; Ramakrishna, BS; Roberts-Thomson, IC; Roediger, WE; Weiss, A	1
Critchley, JA; Prescott, LF; Speirs, GC; Temple, RM; Winney, RJ	1
Baba, S; Nakamura, J; Nakamura, T; Sasaki, H; Shibasaki, J	1
Corcoran, GB; Galinsky, RE; Shum, L; Wong, BK	1
Flanagan, RJ; Prescott, LF; Roberts, I; Strang, J	1
Corcoran, GB; Galinsky, RE	1
Bales, JR; Nicholson, JK; Sadler, PJ; Timbrell, JA	1
Jung, D; Zafar, NU	1
Critchley, JA; Lau, GS	1
Acharya, SK; Davies, MH; Elias, E; Mills, CO; Ngong, JM; Waring, RH; Weaver, JB; Yucesoy, M	1
Birt, DD; Grandjean, AC; Gwilt, PR; Lear, CL; Nagel, DL; Ruddon, RW; Tempero, MA	1
Martin, U; Prescott, LF; Temple, RM; Winney, RJ	1
Birkett, DJ; Miners, JO	1
Franklin, MR; Galinsky, RE; Raftogianis, RB	1
Caddick, S; Farrant, RD; Lindon, JC; Nicholls, AW; Nicholson, JK; Wilson, ID	1
Kim, ND; Kwak, MK; Lee, MG; Lee, WI	1
Anand, KJ; Deinum, JT; Kuizenga, AJ; Okken, A; Quak, JM; Tibboel, D; van Dam, JG; van Lingen, RA	1
Alberti, A; Elia, M; Pirrone, P; Romano, C; Waring, RH	1
Brouwer, KL; Jansen, PL; Turner, KC; Ward, ES; Xiong, H	1
Aster, R; Bougie, D	1
Itoh, H; Nagano, T; Takeyama, M	2
Kulkarni, SG; Pegram, AA; Smith, PC	1
Anderson, BJ; Holford, NH; Jansman, FG; Pluim, MA; Tibboel, D; van den Anker, JN; van der Marel, CD; van Lingen, RA	1
Cherrington, NJ; Klaassen, CD; Maher, JM; Slitt, AL	1
Evans, AM; Jensen, LS; Milne, RW; Valentine, J	1
Chung, JH; Jung, DW; Kim, SJ; Kim, YC; Lee, JY; Moon, CK; Park, HA	1
Allegaert, K; de Hoon, J; Devlieger, H; Tibboel, D; Vanhole, C; Verbesselt, R	1
Chantharaksri, U; Fucharoen, P; Fucharoen, S; Howard, TA; Morales, NP; Sanvarinda, Y; Sirankapracha, P; Tankanitlert, J; Temsakulphong, A; Ware, RE	1
Chantharaksri, U; Fucharoen, P; Fucharoen, S; Howard, TA; Morales, NP; Tankanitlert, J; Ware, RE	1
Boos, J; Hempel, G; Koling, S; Lanvers, C; Würthwein, G	1
Dawson, PA; Hewavitharana, AK; Lee, S; Markovich, D; Shaw, PN	1
Hickling, J; Kumara De Silva, R; Medlicott, NJ; Reith, D; Yang, L; Zacharias, M	1
Aleksunes, LM; Csanaky, IL; Klaassen, CD; Reisman, SA	1
Aantaa, R; Kuusniemi, K; Liukas, A; Neuvonen, PJ; Niemi, M; Olkkola, KT; Virolainen, P	1
McLachlan, AJ; Rittau, AM	1
Doherty, JP; Kulmatycki, K; Li, W; Smith, HT; Tse, FL	1
Allegaert, K; de Hoon, J; Knibbe, CA; Kulo, A; Lewi, L; Peeters, MY; Smits, A; van de Velde, M; Verbesselt, R	1
Adnet, F; Bossard, AE; Bouchemal, N; Fleyfel, M; Galinski, M; Hamza, L; Le Moyec, L; Racine, SX	1
Barnes, DM; Evans, M; Paterson, E	1
Kadowaki, D; Otagiri, M; Seo, H; Taguchi, K; Tokuno, M; Yamasaki, K	1
A-Kader, HH; Bataille, AM; Campion, SN; Canet, MJ; Cherrington, NJ; Erickson, RP; Ferreira, DW; Hardwick, RN; Manautou, JE; Merrell, MD; Xanthakos, SA	1
Court, MH; Epstein, CR; Giesing, D; Greenblatt, DJ; Harmatz, JS; Kadota, T; Kurosaki, C; Nakagawa, Y; Nakamura, T; Zhao, Y	1
Allegaert, K; Danhof, M; de Hoon, J; Knibbe, CA; Krekels, EH; Tibboel, D; van Ham, S	1
Achterbergh, R; Lammers, LA; Mathôt, RA; Pistorius, MC; Romijn, JA	1
Ghallab, A; Hassan, R; Hengstler, JG; Kuepfer, L; Sezgin, S; Spiteller, M; Zühlke, S	1
Amant, F; Annaert, P; Conings, S; Paulus, J; Qi, B; Tseke, F; Van Calsteren, K; Van den Broeck, A	1

Reviews

1 review(s) available for acetaminophen glucuronide and acetaminophen sulfate ester

Article	Year
Kinetics and metabolism of paracetamol and phenacetin. British journal of clinical pharmacology, 1980, Volume: 10 Suppl 2 Topics: Acetaminophen; Administration, Oral; Adult; Animals; Biotransformation; Humans; Intestinal Absorption; Kinetics; Metabolic Clearance Rate; Phenacetin; Tissue Distribution	1980

Trials

10 trial(s) available for acetaminophen glucuronide and acetaminophen sulfate ester

Article	Year
The adverse influence of pregnancy upon sulphation: a clue to the pathogenesis of intrahepatic cholestasis of pregnancy? Journal of hepatology, 1994, Volume: 21, Issue:6 Topics: Acetaminophen; Adult; Arylsulfotransferase; Blood Platelets; Cholestasis; Contraceptives, Oral; Estrogens; Female; Humans; Pregnancy; Pregnancy Complications; Sulfates	1994
Cisapride raises the bioavailability of paracetamol by inhibiting its glucuronidation in man. The Journal of pharmacy and pharmacology, 2001, Volume: 53, Issue:7 Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Area Under Curve; Biological Availability; Cisapride; Drug Interactions; Drug Therapy, Combination; Gastrointestinal Agents; Glucuronosyltransferase; Humans; Male; Statistics, Nonparametric	2001
Effect of nizatidine on paracetamol and its metabolites in human plasma. The Journal of pharmacy and pharmacology, 2002, Volume: 54, Issue:6 Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Area Under Curve; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Histamine H2 Antagonists; Humans; Male; Nizatidine	2002
Paracetamol and metabolite pharmacokinetics in infants. European journal of clinical pharmacology, 2003, Volume: 59, Issue:3 Topics: Acetaminophen; Analgesics, Non-Narcotic; Female; Humans; Infant; Male; Metabolic Clearance Rate; Pain, Postoperative	2003
Intra- and interindividual variability of glucuronidation of paracetamol during repeated administration of propacetamol in neonates. Acta paediatrica (Oslo, Norway : 1992), 2005, Volume: 94, Issue:9 Topics: Acetaminophen; Age Factors; Analgesics; Body Weight; Chromatography, High Pressure Liquid; Gestational Age; Humans; Infant, Newborn; Intensive Care Units, Neonatal; Linear Models; Metabolic Clearance Rate; Multivariate Analysis; Urination	2005
Monitoring paracetamol metabolism after single and repeated administration in pediatric patients with neoplastic diseases. International journal of clinical pharmacology and therapeutics, 2007, Volume: 45, Issue:9 Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Antineoplastic Agents; Benzoquinones; Child; Child, Preschool; Cysteine; Drug Administration Schedule; Drug Interactions; Humans; Imines; Infant; Neoplasms; Oxidation-Reduction	2007
Pharmacokinetics of paracetamol and its metabolites in women at delivery and post-partum. British journal of clinical pharmacology, 2013, Volume: 75, Issue:3 Topics: Acetaminophen; Administration, Intravenous; Adult; Analgesics, Non-Narcotic; Delivery, Obstetric; Dose-Response Relationship, Drug; Female; Humans; Metabolic Clearance Rate; Pain; Pain Measurement; Postpartum Period; Pregnancy	2013
An open label pilot study to evaluate the efficacy of Spanish black radish on the induction of phase I and phase II enzymes in healthy male subjects. BMC complementary and alternative medicine, 2014, Dec-09, Volume: 14 Topics: Acetaminophen; Acetylcysteine; Adult; Area Under Curve; Dietary Supplements; Estradiol; gamma-Glutamyltransferase; Humans; Inactivation, Metabolic; Liver; Male; Pilot Projects; Plant Extracts; Raphanus; Treatment Outcome; Up-Regulation	2014
Favipiravir inhibits acetaminophen sulfate formation but minimally affects systemic pharmacokinetics of acetaminophen. British journal of clinical pharmacology, 2015, Volume: 80, Issue:5 Topics: Acetaminophen; Adult; Amides; Analgesics, Non-Narcotic; Antiviral Agents; Drug Interactions; Female; Humans; In Vitro Techniques; Inhibitory Concentration 50; Male; Middle Aged; Pyrazines; Young Adult	2015
Developmental changes rather than repeated administration drive paracetamol glucuronidation in neonates and infants. European journal of clinical pharmacology, 2015, Volume: 71, Issue:9 Topics: Acetaminophen; Body Weight; Child Development; Computer Simulation; Female; Humans; Infant; Infant, Newborn; Male; Metabolic Clearance Rate; Models, Biological; Up-Regulation	2015

Other Studies

45 other study(ies) available for acetaminophen glucuronide and acetaminophen sulfate ester

Article	Year
The effect of malaria infection on paracetamol disposition in the rat. Biochemical pharmacology, 1991, Jun-01, Volume: 41, Issue:11 Topics: Acetaminophen; Animals; Bile; Half-Life; Inactivation, Metabolic; Liver; Malaria; Male; Mice; Rats	1991
In vivo microdialysis sampling for pharmacokinetic investigations. Pharmaceutical research, 1991, Volume: 8, Issue:3 Topics: Acetaminophen; Animals; Chromatography, Liquid; Dialysis; Dose-Response Relationship, Drug; Microchemistry; Rats; Rats, Inbred Strains; Reproducibility of Results; Spectrophotometry, Ultraviolet	1991
Protective effect of pregnenolone-16 alpha-carbonitrile on acetaminophen-induced hepatotoxicity in hamsters. Toxicology and applied pharmacology, 1991, Jun-15, Volume: 109, Issue:2 Topics: Acetaminophen; Alanine Transaminase; Animals; Biliary Tract; Cricetinae; Cysteine; Dipeptides; Dose-Response Relationship, Drug; Drug Interactions; L-Iditol 2-Dehydrogenase; Liver; Male; Mesocricetus; Pregnenolone Carbonitrile	1991
Dose-dependent intestinal glucuronidation and sulfation of acetaminophen in the rat in situ. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:1 Topics: Acetaminophen; Animals; Biotransformation; Dose-Response Relationship, Drug; Glucose; Intestinal Mucosa; Male; Rats; Rats, Inbred Strains	1990
Altered hepatobiliary disposition of acetaminophen metabolites after phenobarbital pretreatment and renal ligation: evidence for impaired biliary excretion and a diffusional barrier. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:2 Topics: Acetaminophen; Animals; Bile; Bile Ducts; Diffusion; Kidney; Ligation; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains	1990
First-pass metabolism of acetaminophen in rats after low and high doses. Biopharmaceutics & drug disposition, 1990, Volume: 11, Issue:3 Topics: Acetaminophen; Animals; Chromatography, High Pressure Liquid; Male; Rats; Rats, Inbred Strains; Tissue Distribution	1990
Disposition of phenacetin in rabbits pretreated orally and intraperitoneally with 3,4-benzpyrene. Journal of pharmacobio-dynamics, 1989, Volume: 12, Issue:7 Topics: Acetaminophen; Administration, Oral; Animals; Benzo(a)pyrene; Enzyme Induction; Injections, Intraperitoneal; Liver; Male; Phenacetin; Rabbits	1989
Acetaminophen metabolism in vivo by pregnant, fetal, and neonatal guinea pigs. Journal of biochemical toxicology, 1989,Winter, Volume: 4, Issue:4 Topics: Acetaminophen; Animals; Animals, Newborn; Biotransformation; Female; Fetus; Guinea Pigs; Pregnancy; Pregnancy, Animal	1989
Estimation of phenolic conjugation by colonic mucosa. Journal of clinical pathology, 1989, Volume: 42, Issue:6 Topics: Acetaminophen; Colon; Dialysis; Humans; Intestinal Mucosa; Phenols; Rectum	1989
Paracetamol disposition and metabolite kinetics in patients with chronic renal failure. European journal of clinical pharmacology, 1989, Volume: 36, Issue:3 Topics: Acetaminophen; Adult; Aged; Female; Half-Life; Humans; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Time Factors	1989
A method for the preparation of calibration curves for acetaminophen glucuronide and acetaminophen sulfate in rabbit urine without use of authentic compounds in high-performance liquid chromatography. Journal of pharmacobio-dynamics, 1987, Volume: 10, Issue:11 Topics: Acetaminophen; Animals; Chromatography, High Pressure Liquid; Male; Rabbits; Reference Values	1987
Acetaminophen sulfation deficit in obese rats overfed an energy-dense cafeteria diet. Endocrine research, 1987, Volume: 13, Issue:2 Topics: Acetaminophen; Animals; Biotransformation; Kinetics; Male; Obesity; Rats; Rats, Inbred Strains	1987
Toxicological studies in a Distalgesic addict. Human toxicology, 1986, Volume: 5, Issue:3 Topics: Acetaminophen; Adult; Dextropropoxyphene; Drug Combinations; Humans; Kinetics; Male; Substance-Related Disorders	1986
Influence of advanced age on the formation and elimination of acetaminophen metabolites by male rats. Pharmacology, 1986, Volume: 32, Issue:6 Topics: Acetaminophen; Aging; Animals; Biotransformation; Kinetics; Male; Rats; Rats, Inbred F344	1986
A high resolution proton nuclear magnetic resonance approach to the study of hepatocyte and drug metabolism. Application to acetaminophen. Molecular pharmacology, 1985, Volume: 27, Issue:6 Topics: Acetaminophen; Animals; Deuterium; In Vitro Techniques; Kinetics; Liver; Magnetic Resonance Spectroscopy; Rats; Rats, Inbred Strains	1985
Micro high-performance liquid chromatographic assay of acetaminophen and its major metabolites in plasma and urine. Journal of chromatography, 1985, Apr-12, Volume: 339, Issue:1 Topics: Acetaminophen; Chromatography, High Pressure Liquid; Humans	1985
The estimation of paracetamol and its major metabolites in both plasma and urine by a single high-performance liquid chromatography assay. Journal of pharmaceutical and biomedical analysis, 1994, Volume: 12, Issue:12 Topics: Acetaminophen; Chromatography, High Pressure Liquid; Cysteine; Humans; Spectrophotometry, Ultraviolet	1994
The effect of garlic extract on human metabolism of acetaminophen. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1994, Volume: 3, Issue:2 Topics: Acetaminophen; Adult; Allyl Compounds; Carcinogens; Garlic; Half-Life; Humans; Inactivation, Metabolic; Male; Metabolic Clearance Rate; Neoplasms; Plant Extracts; Plants, Medicinal; Sulfides	1994
The disposition of paracetamol and its conjugates during multiple dosing in patients with end-stage renal failure maintained on haemodialysis. European journal of clinical pharmacology, 1993, Volume: 45, Issue:2 Topics: Acetaminophen; Administration, Oral; Adult; Cysteine; Drug Administration Schedule; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis	1993
The misuse of urinary metabolite excretion data in drug metabolism studies. Pharmacogenetics, 1993, Volume: 3, Issue:1 Topics: Acetaminophen; Asian People; Genetic Variation; Humans; White People	1993
Effect of lipid-free total parenteral nutrition on hepatic drug conjugation in rats. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 276, Issue:2 Topics: Acetaminophen; Animals; Enteral Nutrition; Glucuronosyltransferase; Liver; Male; Parenteral Nutrition, Total; Rats; Rats, Sprague-Dawley	1996
NMR spectroscopic studies on the metabolism and futile deacetylation of phenacetin in the rat. Xenobiotica; the fate of foreign compounds in biological systems, 1997, Volume: 27, Issue:11 Topics: Acetaminophen; Acetylation; Animals; Deuterium; Magnetic Resonance Spectroscopy; Male; Phenacetin; Rats; Rats, Sprague-Dawley	1997
Metabolic changes of acetaminophen after intravenous administration to rats pretreated with 2-(allylthio)pyrazine. Biopharmaceutics & drug disposition, 1998, Volume: 19, Issue:4 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Inactivation, Metabolic; Male; Pyrazines; Rats; Rats, Sprague-Dawley	1998
Pharmacokinetics and metabolism of rectally administered paracetamol in preterm neonates. Archives of disease in childhood. Fetal and neonatal edition, 1999, Volume: 80, Issue:1 Topics: Acetaminophen; Administration, Rectal; Analgesics, Non-Narcotic; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gestational Age; Half-Life; Humans; Infant, Newborn; Infant, Premature; Male; Pain Measurement; Regression Analysis; Statistics, Nonparametric; Time Factors	1999
Sulphation deficit in "low-functioning" autistic children: a pilot study. Biological psychiatry, 1999, Aug-01, Volume: 46, Issue:3 Topics: Acetaminophen; Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Autistic Disorder; Child; Child, Preschool; Chromatography, High Pressure Liquid; Female; Food; Humans; Male; Metabolism, Inborn Errors; Pilot Projects; Sulfates	1999
Altered hepatobiliary disposition of acetaminophen glucuronide in isolated perfused livers from multidrug resistance-associated protein 2-deficient TR(-) rats. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 295, Issue:2 Topics: Acetaminophen; Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily B; Bicarbonates; Biliary Tract; Biological Transport; Cell Membrane; Hydrogen-Ion Concentration; Liver; Male; Membrane Potentials; Membrane Transport Proteins; Models, Biological; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Perfusion; Rats; Rats, Sprague-Dawley; Rats, Wistar	2000
Immune thrombocytopenia resulting from sensitivity to metabolites of naproxen and acetaminophen. Blood, 2001, Jun-15, Volume: 97, Issue:12 Topics: Acetaminophen; Adult; Aged; Antibodies; Blood Platelets; Female; Glucuronides; Humans; Male; Middle Aged; Naproxen; Platelet Glycoprotein GPIIb-IIIa Complex; Purpura, Thrombocytopenic, Idiopathic	2001
Disposition of acetaminophen and indocyanine green in cystic fibrosis-knockout mice. AAPS pharmSci, 2000, Volume: 2, Issue:2 Topics: Acetaminophen; Animals; Cystic Fibrosis; Indocyanine Green; Male; Mice; Mice, Knockout; Models, Animal; Organ Specificity	2000
Induction of multidrug resistance protein 3 in rat liver is associated with altered vectorial excretion of acetaminophen metabolites. Drug metabolism and disposition: the biological fate of chemicals, 2003, Volume: 31, Issue:9 Topics: Acetaminophen; Allyl Compounds; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Bile; Blotting, Western; Branched DNA Signal Amplification Assay; Drug Resistance, Multiple; Kidney; Liver; Male; Mitochondrial Proteins; Phenobarbital; Pyrazines; Rats; Rats, Sprague-Dawley; Ribosomal Proteins; RNA, Messenger; Saccharomyces cerevisiae Proteins; Stilbenes; Sulfides; Thiones; Thiophenes; Time Factors	2003
The quantification of paracetamol, paracetamol glucuronide and paracetamol sulphate in plasma and urine using a single high-performance liquid chromatography assay. Journal of pharmaceutical and biomedical analysis, 2004, Feb-18, Volume: 34, Issue:3 Topics: Acetaminophen; Chromatography, High Pressure Liquid; Humans	2004
Effect of taurine on biliary excretion and metabolism of acetaminophen in male hamsters. Biological & pharmaceutical bulletin, 2004, Volume: 27, Issue:11 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Bile; Cricetinae; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Male; Mesocricetus; Taurine; Time Factors	2004
A pharmacokinetic study of paracetamol in Thai beta-thalassemia/HbE patients. European journal of clinical pharmacology, 2006, Volume: 62, Issue:9 Topics: Acetaminophen; Adult; Area Under Curve; beta-Thalassemia; Bilirubin; Cysteine; Female; Glucuronosyltransferase; Humans; Male; Middle Aged	2006
Effects of combined UDP-glucuronosyltransferase (UGT) 1A128 and 1A62 on paracetamol pharmacokinetics in beta-thalassemia/HbE. Pharmacology, 2007, Volume: 79, Issue:2 Topics: Acetaminophen; Adult; Analgesics; Area Under Curve; Asian People; beta-Thalassemia; Female; Glucuronosyltransferase; Half-Life; Hemoglobin E; Humans; Male; Metabolic Clearance Rate; Middle Aged; Polymorphism, Genetic	2007
Development of an HPLC-MS/MS method for the selective determination of paracetamol metabolites in mouse urine. Analytical biochemistry, 2008, Mar-01, Volume: 374, Issue:1 Topics: Acetaminophen; Animals; Chromatography, High Pressure Liquid; Male; Mice; Sensitivity and Specificity; Tandem Mass Spectrometry	2008
Simultaneous modelling of the Michaelis-Menten kinetics of paracetamol sulphation and glucuronidation. Clinical and experimental pharmacology & physiology, 2009, Volume: 36, Issue:1 Topics: Acetaminophen; Adult; Chromatography, High Pressure Liquid; Cross-Over Studies; Cysteine; Dose-Response Relationship, Drug; Female; Humans; Male; Molecular Structure; Pain; Time; Young Adult	2009
Altered disposition of acetaminophen in Nrf2-null and Keap1-knockdown mice. Toxicological sciences : an official journal of the Society of Toxicology, 2009, Volume: 109, Issue:1 Topics: Acetaminophen; Adaptor Proteins, Signal Transducing; Animals; Bile; Biotransformation; Carrier Proteins; Cytoskeletal Proteins; Gene Knockdown Techniques; Guinea Pigs; Kelch-Like ECH-Associated Protein 1; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Fluorescence; Microsomes, Liver; NAD(P)H Dehydrogenase (Quinone); NADPH Dehydrogenase; NF-E2-Related Factor 2	2009
Pharmacokinetics of intravenous paracetamol in elderly patients. Clinical pharmacokinetics, 2011, Volume: 50, Issue:2 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Aging; Analgesia; Analgesics, Non-Narcotic; Area Under Curve; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Female; Genotype; Glomerular Filtration Rate; Half-Life; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasm Proteins; Polymorphism, Single Nucleotide; Sex Characteristics; Young Adult	2011
Investigating paracetamol pharmacokinetics using venous and capillary blood and saliva sampling. The Journal of pharmacy and pharmacology, 2012, Volume: 64, Issue:5 Topics: Acetaminophen; Adult; Area Under Curve; Capillaries; Chromatography, High Pressure Liquid; Female; Humans; Middle Aged; Reference Values; Reproducibility of Results; Saliva; Veins; Young Adult	2012
Simultaneous LC-MS/MS quantitation of acetaminophen and its glucuronide and sulfate metabolites in human dried blood spot samples collected by subjects in a pilot clinical study. Bioanalysis, 2012, Volume: 4, Issue:12 Topics: Acetaminophen; Analgesics, Non-Narcotic; Chromatography, Reverse-Phase; Dried Blood Spot Testing; Humans; Limit of Detection; Methanol; Pilot Projects; Reference Standards; Solid Phase Extraction; Tandem Mass Spectrometry	2012
Detection and follow-up, after partial liver resection, of the urinary paracetamol metabolites by proton NMR spectroscopy. Pharmacology, 2014, Volume: 93, Issue:1-2 Topics: Acetaminophen; Analgesics; Benzoquinones; Female; Humans; Imines; Liver; Magnetic Resonance Spectroscopy; Male; Middle Aged	2014
Establishment of a model of acetaminophen-induced hepatotoxicity in different weekly-aged ICR mice. Laboratory animals, 2015, Volume: 49, Issue:4 Topics: Acetaminophen; Age Factors; Analgesics, Non-Narcotic; Animals; Injections, Intraperitoneal; Liver; Male; Mice; Mice, Inbred ICR	2015
Altered regulation of hepatic efflux transporters disrupts acetaminophen disposition in pediatric nonalcoholic steatohepatitis. Drug metabolism and disposition: the biological fate of chemicals, 2015, Volume: 43, Issue:6 Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Bile Canaliculi; Biotransformation; Child; Cohort Studies; Fatty Liver; Female; Humans; Liver; Male; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Non-alcoholic Fatty Liver Disease; Pilot Projects; Protein Transport; Up-Regulation	2015
Quantitative Method for Simultaneous Analysis of Acetaminophen and 6 Metabolites. Therapeutic drug monitoring, 2017, Volume: 39, Issue:2 Topics: Acetaminophen; Aminophenols; Calibration; Chromatography, High Pressure Liquid; Humans; Limit of Detection; Plasma; Reproducibility of Results; Tandem Mass Spectrometry	2017
Spatio-temporal visualization of the distribution of acetaminophen as well as its metabolites and adducts in mouse livers by MALDI MSI. Archives of toxicology, 2018, Volume: 92, Issue:9 Topics: Acetaminophen; Animals; Benzoquinones; Cytochrome P-450 CYP2E1; Dose-Response Relationship, Drug; Glutathione; Imines; Liver; Male; Mice, Inbred C57BL; Spatio-Temporal Analysis; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2018
Transplacental transport of paracetamol and its phase II metabolites using the ex vivo placenta perfusion model. Toxicology and applied pharmacology, 2019, 05-01, Volume: 370 Topics: Acetaminophen; Adult; Female; Fetus; Gestational Age; Humans; In Vitro Techniques; Maternal-Fetal Exchange; Perfusion; Placenta; Pregnancy	2019