Compounds > acetaminophen

acetaminophen and urea

acetaminophen has been researched along with urea in 67 studies

Research

Studies (67)

TimeframeStudies, this research(%)All Research%
pre-199021 (31.34)18.7374
1990's5 (7.46)18.2507
2000's9 (13.43)29.6817
2010's25 (37.31)24.3611
2020's7 (10.45)2.80

Authors

AuthorsStudies
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Avdeef, A; Tam, KY1
Richens, A1
Arita, T; Hori, R; Ito, K; Nakano, M; Sekikawa, H1
el-Banna, HM1
el-Banna, HM; Gouda, MW; Khalil, SA1
Clark, EC; Joubert, PH; Otto, AC; Pannall, PR1
Bindra, DS; Wilson, GS1
Cockaerts, P1
Acosta, D; Anuforo, DC; Mitchell, DB; Ramos, K; Santone, KS; Smith, MA; Sorensen, EM1
Chikasue, F; Kojima, T; Miyazaki, T; Okamoto, I; Yashiki, M1
Asscher, AW; Elwood, PC; Waters, WE1
Ando, A; Orita, Y; Shirai, D; Takamitsu, Y; Urakabe, S1
Nachtigall, C1
Peters, G1
Fragen, CA1
Balme, HW; Berry, H; Hart, FD; Huskisson, EC; Scott, J; Wojtulewski, JA1
Barraclough, MA; Nilam, F1
Blendis, LM; Wilkinson, SP; Williams, R1
Baechtold-Fowler, N; Bonjour, JP; Chométy-Diézi, F; Filloux, B; Guidoux, R; Guignard, JP; Hedinger, C; Peters, G; Peters-Haefeli, L; Roch-Ramel, F; Schelling, JL; Weber, E1
Barraclough, MA1
Adjukiewicz, AB; Chalstrey, LJ; Hillenbrand, P; James, IM; Kennedy, J; Parbhoo, SP1
Carroll, JD; Stephens, JD; Toghill, PJ; Williams, R1
Burrin, JM; Price, CP; Sylvester, EC1
Kondo, T; Lin, Z; Nagano, T; Nakaya, T; Nishigami, J; Ohshima, T; Sawaguchi, T; Takayasu, T1
Kauffman, FC; Pang, JM; Zaleski, J1
Dalhoff, K; Jensen, SA; Krog, B; Tygstrup, N1
Berkovitch, M; Chen-Levy, Z; Eshel, G; Koren, G; Lushkov, G; Pinto, O; Reznik, S1
Brunner, M; Eichler, HG; Erovic, B; Joukhadar, C; Müller, M; Schmid, R1
Farkas, D; Tannenbaum, SR1
Abraham, P; Dian, BJ; Kanakasabapathy, I1
Berg, C; Hengstler, JG; Runge, D; Ullrich, A1
Chen, C; Gonzalez, FJ; Idle, JR; Krausz, KW1
Dow, MA; Pettie, JM; Robinson, OD; Stephen, AF; Waring, WS1
Ray, AR; Ray, P; Verma, P; Verma, V1
Molinas, SM; Monasterolo, LA; Pagotto, MA; Pisani, GB; Rosso, M; Trumper, L; Wayllace, NZ1
Ellis, EC; Hengstler, JG; Michalopoulos, GK; Runge, D; Stolz, DB; Strom, SC; Ullrich, A1
Al-Jabi, SW; Awang, R; Sulaiman, SA; Zyoud, SH1
Kumar, BS; Kumar, RP; Palani, S; Raja, S; Selvaraj, R1
Kumar, BS; Kumar, SN; Palani, S; Raja, S1
Ahmed, OG; El-Mottaleb, NA1
Borchers, S; Findeisen, R; Krauss, M; Kuepfer, L; Lippert, J; Schaller, S1
Gunness, P; Heinzle, E; Ingelman-Sundberg, M; Mueller, D; Noor, F; Shevchenko, V1
Agilli, M; Alp, BF; Altayli, E; Aydin, FN; Aydin, I; Cayci, T; Cermik, H; Ozkan, E; Taslipinar, MY; Toygar, M; Ucar, F1
Andersen, ME; Aoyama, S; Khetani, SR; Krzyzewski, S; Lecluyse, EL; McVay, M; Rose, K; Ukairo, O1
Abo-Elmatty, DM; Aly, HF; Desoky, MM; Ibrahim, NA; Rizk, MZ; Younis, EA1
Borlak, J; Chougule, A; Singh, PK1
Das, K; Mahapatra, SD; Mahapatra, TD; Mandal, A; Mandal, S; Mondal, KC; Nandi, DK; Patra, A; Paul, T; Roy, S1
Alabalık, U; Aycan, İÖ; Çelik, F; Evliyaoğlu, O; Güzel, A; Tokgöz, O; Tüfek, A; Turgut, H1
Boyer, TH; Huang, CH; Landry, KA; Sun, P1
Cortez-Álvarez, CR; Escutia-Gutiérrez, R; García-Lemus, CR; Luna-Záizar, H; Mendizabal-Ruiz, AP; Ruiz-Quezada, SL; Virgen-Montelongo, M1
Atmaca, HT; Bayir, Y; Canayakin, D; Halici, Z; Keles, MS; Kilic Baygutalp, N; Kocak Ozgeris, FB; Sezen Karaoglan, E1
Cheng, C; Gaydarova, R; Ivanoff, CS; Kevorkyan, S; Mirzajani, H; Tomlekova, D; Wu, JJ; Yuan, Q1
Braun, A; Dasenbrock, C; Granitzny, A; Hansen, T; Knebel, J; Schaudien, D; Steinberg, P1
Mokhtarpour, M; Shekaari, H; Zafarani-Moattar, MT1
Abe, J; Fukuda, A; Hasegawa, S; Hatahira, H; Iguchi, K; Kato, Y; Motooka, Y; Naganuma, M; Nakamura, M; Nakao, S; Ohmori, T; Sasaoka, S; Shimauchi, A1
Annich, GM; Mueller, BA; Scoville, BA; Vulaj, V; Wagner, DS1
Bukasov, R; Elemessova, Z; Gudun, K; Khamkhash, L; Mukanova, Z; Ralchenko, E1
Boisen, A; Durucan, O; Rindzevicius, T; Viehrig, M; Wu, K1
Aksakal, M; Arkalı, G; Cellat, M; Gökçek, İ; Güvenç, M; Özkan, H; Yakan, A; Yurdagül Özsoy, Ş1
Chen, GH; Chen, SX; Diao, J; Gao, L; Hong, MK; Jia, H; Li, J; Liu, HH; Zhang, DD; Zhao, D; Zheng, SY; Zhu, JQ1
Akbarpour, B; Asmarian, S; Gholyaf, M; Mohammadi, F1
Alharbi, M; Ali, W; Alshammari, A; Aziz, T; Iqbal, Z; Jamil, S; Khan, AA; Khan, FF; Shahzad, M; Ur Rahman, S; Zahid, M1
Baldo, TA; Feitosa, MHA; Moraes, FC; Proença, CA; Santos, AM; Sotomayor, MDPT; Wong, A1
Ashraf, H; Irfan, M; Khan, WA; Makhdoom, M; Makhdoom, S; Maqbool, A; Muhammad, H1
Berninzoni, D; D'Alessandro, A; Dylla, L; Hart, C; Heard, KJ; Monte, AA; Pattee, J; Reisz, JA; Vest, A; Wood, C1

Reviews

1 review(s) available for acetaminophen and urea

ArticleYear
Interactions with antiepileptic drugs.
    Drugs, 1977, Volume: 13, Issue:4

    Topics: Acetaminophen; Acetazolamide; Anti-Anxiety Agents; Anticoagulants; Anticonvulsants; Carbamazepine; Diazepam; Drug Interactions; Furosemide; Gonadal Steroid Hormones; Griseofulvin; Humans; Phenobarbital; Phenytoin; Primidone; Thiazines; Urea; Valproic Acid; Vitamin D

1977

Trials

3 trial(s) available for acetaminophen and urea

ArticleYear
Treatment of rheumatoid arthritis with fenoprofen: comparison with aspirin.
    British medical journal, 1974, Feb-02, Volume: 1, Issue:5900

    Topics: Acetaminophen; Arthritis, Rheumatoid; Aspirin; Body Temperature; Clinical Trials as Topic; Deafness; Gastrointestinal Diseases; Humans; Movement; Pain; Placebos; Propionates; Tinnitus; Urea; Uric Acid; Wrist

1974
Effect of vasopressin on the reabsorption of phenacetin and its metabolites from the tubular fluid in man.
    Clinical science, 1972, Volume: 43, Issue:5

    Topics: Acetaminophen; Aniline Compounds; Creatinine; Diuresis; Humans; Kidney Papillary Necrosis; Kidney Tubules; Phenacetin; Urea; Vasopressins

1972
A Multi-Omic Mosaic Model of Acetaminophen Induced Alanine Aminotransferase Elevation.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2023, Volume: 19, Issue:3

    Topics: Acetaminophen; Alanine Transaminase; Chemical and Drug Induced Liver Injury; Genome-Wide Association Study; Humans; Maltose; Multiomics; Urea

2023

Other Studies

63 other study(ies) available for acetaminophen and urea

ArticleYear
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Effects of macromolecular additives and urea on the intestinal absorption of acetaminophen in rats.
    Chemical & pharmaceutical bulletin, 1979, Volume: 27, Issue:5

    Topics: Acetaminophen; Animals; Excipients; Intestinal Absorption; Macromolecular Substances; Male; Rats; Urea

1979
Solid dispersion of pharmaceutical ternary systems I: Phase diagram of aspirin-acetaminophen-urea system.
    Journal of pharmaceutical sciences, 1978, Volume: 67, Issue:8

    Topics: Acetaminophen; Aspirin; Drug Combinations; Models, Chemical; Thermodynamics; Urea

1978
Solid dispersion of pharmaceutical ternary systems II: Dissolution studies on aspirin-acetaminophen-urea system.
    Journal of pharmaceutical sciences, 1978, Volume: 67, Issue:8

    Topics: Acetaminophen; Aspirin; Drug Combinations; Kinetics; Osmolar Concentration; Solubility; Thermodynamics; Urea

1978
Unreliable drug histories, analgesics, and changes in renal function.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1977, Jul-16, Volume: 52, Issue:3

    Topics: Acetaminophen; Analgesics; Creatinine; Female; Humans; Male; Medical History Taking; Middle Aged; Salicylates; Substance-Related Disorders; Urea

1977
Pulsed amperometric detection of glucose in biological fluids at a surface-modified gold electrode.
    Analytical chemistry, 1989, Nov-15, Volume: 61, Issue:22

    Topics: Acetaminophen; Amino Acids; Blood Glucose; Body Fluids; Electrochemistry; Electrodes; Gold; Humans; Urea

1989
[Analysis of Perdolan tablets using high pressure liquid chromatography].
    Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie, 1985, Volume: 47, Issue:5

    Topics: Acetaminophen; Analgesics; Aspirin; Bromisovalum; Caffeine; Chromatography, High Pressure Liquid; Codeine; Drug Combinations; Pharmaceutical Vehicles; Urea

1985
An in vitro approach to the study of target organ toxicity of drugs and chemicals.
    In vitro cellular & developmental biology : journal of the Tissue Culture Association, 1985, Volume: 21, Issue:9

    Topics: Acetaminophen; Animals; Antidepressive Agents, Tricyclic; Biotransformation; Cell Survival; Cells, Cultured; Cephaloridine; Heart; Isoproterenol; Kidney Cortex; Lactates; Lactic Acid; Liver; Metals; Myocardial Contraction; Myocardium; Pyruvates; Pyruvic Acid; Rats; Toxicology; Urea

1985
[Extrelut column extraction for screening of drugs in biological materials by gas chromatography and gas chromatography-mass spectrometry--a fatal poisoning by ingestion of a drug containing acetaminophen, ethenzamide and bromvalerylurea].
    Nihon hoigaku zasshi = The Japanese journal of legal medicine, 1985, Volume: 39, Issue:5

    Topics: Acetaminophen; Adult; Bromisovalum; Chromatography, Gas; Female; Gas Chromatography-Mass Spectrometry; Humans; Salicylamides; Stomach; Suicide; Urea

1985
Community survey of analgesic consumption and kidney function in women.
    Lancet (London, England), 1973, Feb-17, Volume: 1, Issue:7799

    Topics: Acetaminophen; Adult; Age Factors; Analgesics; Blood Pressure; Chronic Disease; Creatinine; Female; Humans; Kidney; Middle Aged; Phenacetin; Surveys and Questionnaires; Urea; Urinary Tract Infections

1973
Effect of urea derivatives and analgetics on the permeability to water and electrical properties of the urinary bladder of the toad.
    Japanese circulation journal, 1970, Volume: 34, Issue:7

    Topics: Acetaminophen; Acetanilides; Aminopyrine; Analgesics; Animals; Anura; Biological Transport; Cell Membrane Permeability; Cyclic AMP; Depression, Chemical; Electrophysiology; Epinephrine; Oxyphenbutazone; Phenylbutazone; Stimulation, Chemical; Urea; Urinary Bladder; Vasopressins; Water

1970
[Paidipyrin--a phenacetin free antipyretic for children].
    Medizinische Monatsschrift, 1967, Volume: 21, Issue:11

    Topics: Acetaminophen; Analgesics; Child; Child, Preschool; Fever; Humans; Infant; Urea

1967
[Analgesia and antipyresis in pediatric orthopedics].
    Deutsches medizinisches Journal, 1970, Jan-05, Volume: 21, Issue:1

    Topics: Acetaminophen; Analgesics; Butyrates; Child; Child, Preschool; Fracture Fixation; Humans; Infant; Orthopedics; Postoperative Care; Preoperative Care; Suppositories; Urea

1970
[Antipyresis in pediatrics].
    Monatsschrift fur Kinderheilkunde, 1972, Volume: 120, Issue:5

    Topics: Acetaminophen; Analgesics; Child, Preschool; Diphenylacetic Acids; Drug Combinations; Fever; Humans; Infant; Suppositories; Urea

1972
Effect of vasopressin on the renal tubular reabsorption and cortico-papillary concentration gradient of phenacetin and its metabolites.
    Experientia, 1972, Sep-15, Volume: 28, Issue:9

    Topics: Acetaminophen; Animals; Dogs; Female; Kidney; Kidney Concentrating Ability; Kidney Cortex; Kidney Tubules; Phenacetin; Urea; Vasopressins

1972
Frequency and type of renal and electrolyte disorders in fulminant hepatic failure.
    British medical journal, 1974, Feb-02, Volume: 1, Issue:5900

    Topics: Acetaminophen; Acute Kidney Injury; Blood Glucose; Chemical and Drug Induced Liver Injury; Creatinine; Diuresis; Halothane; Hepatitis A; Hepatitis B; Humans; Kidney Diseases; Liver Diseases; Potassium; Sodium; Urea; Uremia; Water-Electrolyte Balance

1974
General and renal toxicity of phenacetin, paracetamol and some anti-mitotic agents in the rat.
    Archiv fur Toxikologie, 1972, Volume: 28, Issue:4

    Topics: Acetaminophen; Anemia, Macrocytic; Anilides; Animals; Blood; Blood Glucose; Body Weight; Caffeine; Depression, Chemical; Diuresis; Feeding Behavior; Glomerular Filtration Rate; Growth; Kidney; Male; Mercaptopurine; Methemoglobinemia; Phenacetin; Rats; Urea; Urine

1972
Extracorporeal perfusion of pig liver in the treatment of acute liver failure.
    The British journal of surgery, 1971, Volume: 58, Issue:10

    Topics: Acetaminophen; Adult; Animals; Bilirubin; Brain; Chemical and Drug Induced Liver Injury; Electroencephalography; Fatty Liver; Female; Glucose; Hepatic Encephalopathy; Hepatitis A; Hepatitis B; Humans; Liver; Male; Middle Aged; Necrosis; Oxygen Consumption; Perfusion; Radionuclide Imaging; Serum Albumin; Swine; Urea

1971
Acute hepatic necrosis following an overdose of paracetamol.
    Gastroenterology, 1969, Volume: 56, Issue:4

    Topics: Acetaminophen; Acute Disease; Acute Kidney Injury; Adult; Bilirubin; Blood Glucose; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Necrosis; Plasma; Substance-Related Disorders; Suicide; Urea

1969
Investigation of the potential for interference with whole blood glucose strips.
    Annals of clinical biochemistry, 1994, Volume: 31 ( Pt 1)

    Topics: Acetaminophen; Ascorbic Acid; Blood Chemical Analysis; Blood Glucose; Blood Specimen Collection; Creatinine; Glucose Oxidase; Humans; Hydrogen Peroxide; Oxidation-Reduction; Reagent Strips; Reference Standards; Regression Analysis; Salicylates; Salicylic Acid; Urea; Uric Acid

1994
[A fatal case due to intoxication with seven drugs detected by GC-MS and TDx methods].
    Nihon hoigaku zasshi = The Japanese journal of legal medicine, 1993, Volume: 47, Issue:1

    Topics: Acetaminophen; Adult; Bromisovalum; Caffeine; Drug Overdose; Female; Fluorescent Antibody Technique; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Ibuprofen; Salicylamides; Suicide; Urea

1993
Actions of selected hepatotoxicants on freshly isolated and cryopreserved rat hepatocytes.
    Cryobiology, 1996, Volume: 33, Issue:2

    Topics: 1-Propanol; Acetaminophen; Adenosine Triphosphate; Animals; Carbon Tetrachloride; Cell Separation; Cryopreservation; Digitonin; Energy Metabolism; In Vitro Techniques; Liver; Male; Oxygen Consumption; Propanols; Rats; Rats, Sprague-Dawley; Urea

1996
Expression of liver-specific functions in rat hepatocytes following sublethal and lethal acetaminophen poisoning.
    Journal of hepatology, 1996, Volume: 25, Issue:2

    Topics: Acetaminophen; Acute-Phase Proteins; Animals; Enzymes; Female; Liver; Liver Regeneration; Proteins; Rats; Rats, Wistar; RNA, Messenger; Urea

1996
The effect of diazepam in the recovery of rabbits from acute acetaminophen intoxication.
    Therapeutic drug monitoring, 1999, Volume: 21, Issue:3

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Aspartate Aminotransferases; Creatinine; Diazepam; Drug Evaluation, Preclinical; Male; Rabbits; Survival Rate; Treatment Outcome; Urea

1999
Validation of urea as an endogenous reference compound for the in vivo calibration of microdialysis probes.
    Life sciences, 2000, Jul-14, Volume: 67, Issue:8

    Topics: Acetaminophen; Adult; Calibration; Female; Glucose; Humans; Male; Microdialysis; Urea

2000
Characterization of chemically induced hepatotoxicity in collagen sandwiches of rat hepatocytes.
    Toxicological sciences : an official journal of the Society of Toxicology, 2005, Volume: 85, Issue:2

    Topics: Acetaminophen; Aflatoxin B1; Albumins; Animals; Benzoquinones; Blotting, Western; Carbon Tetrachloride; Cells, Cultured; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Collagen; Cytochrome P-450 Enzyme System; Dimethylformamide; Glucuronides; Glutathione; Hepatocytes; Isoenzymes; L-Lactate Dehydrogenase; Mass Spectrometry; Oxazines; Rats; Sulfates; Urea; Vinyl Compounds; Xanthenes

2005
Propylthiouracil attenuates acetaminophen-induced renal damage in the rat.
    Nephrology (Carlton, Vic.), 2005, Volume: 10, Issue:6

    Topics: Acetaminophen; Animals; Creatinine; Dose-Response Relationship, Drug; Kidney; Kidney Diseases; Lipid Peroxides; Male; Propylthiouracil; Rats; Rats, Wistar; Sulfhydryl Compounds; Urea

2005
Use of a standardised and validated long-term human hepatocyte culture system for repetitive analyses of drugs: repeated administrations of acetaminophen reduces albumin and urea secretion.
    ALTEX, 2007, Volume: 24, Issue:1

    Topics: Acetaminophen; Albumins; Analgesics, Non-Narcotic; Animal Testing Alternatives; Animals; Cells, Cultured; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Dose-Response Relationship, Drug; Humans; Liver; Urea

2007
Identification of novel toxicity-associated metabolites by metabolomics and mass isotopomer analysis of acetaminophen metabolism in wild-type and Cyp2e1-null mice.
    The Journal of biological chemistry, 2008, Feb-22, Volume: 283, Issue:8

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Biomarkers; Cytochrome P-450 CYP2E1; Dose-Response Relationship, Drug; Genotype; Glutathione; Hydrogen Peroxide; Liver; Mass Spectrometry; Mice; Mice, Mutant Strains; Oxidative Stress; Time Factors; Transaminases; Urea

2008
Serum urea concentration and the risk of hepatotoxicity after paracetamol overdose.
    QJM : monthly journal of the Association of Physicians, 2008, Volume: 101, Issue:5

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Biomarkers; Blood Glucose; Chemical and Drug Induced Liver Injury; Drug Overdose; Epidemiologic Methods; Female; Humans; Male; Urea

2008
Agar-gelatin hybrid sponge-induced three-dimensional in vitro 'liver-like' HepG2 spheroids for the evaluation of drug cytotoxicity.
    Journal of tissue engineering and regenerative medicine, 2009, Volume: 3, Issue:5

    Topics: Acetaminophen; Agar; Albumins; Analgesics, Non-Narcotic; Cell Culture Techniques; Cell Line; Drug Evaluation, Preclinical; Gelatin; Gene Expression Regulation; Humans; Inhibitory Concentration 50; Kinetics; Liver; Microscopy; Urea

2009
Heat shock protein 70 induction and its urinary excretion in a model of acetaminophen nephrotoxicity.
    Pediatric nephrology (Berlin, Germany), 2010, Volume: 25, Issue:7

    Topics: Acetaminophen; Acetylglucosaminidase; Analgesics, Non-Narcotic; Animals; Creatinine; Disease Models, Animal; Glutathione; HSP70 Heat-Shock Proteins; Kidney; Kidney Diseases; Kidney Function Tests; Liver; Male; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Urea

2010
Long term cultures of primary human hepatocytes as an alternative to drug testing in animals.
    ALTEX, 2009, Volume: 26, Issue:4

    Topics: Acetaminophen; Albumins; Animal Testing Alternatives; Cell Culture Techniques; Culture Media, Serum-Free; Glycogen; Hepatocytes; Humans; L-Lactate Dehydrogenase; Time Factors; Urea

2009
Impact of serum acetaminophen concentration on changes in serum potassium, creatinine and urea concentrations among patients with acetaminophen overdose.
    Pharmacoepidemiology and drug safety, 2011, Volume: 20, Issue:2

    Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Biomarkers; Child; Child, Preschool; Creatinine; Dose-Response Relationship, Drug; Drug Overdose; Female; Humans; Malaysia; Male; Middle Aged; Potassium; Retrospective Studies; Time Factors; Urea; Young Adult

2011
Evaluation of phytoconstituents and anti-nephrotoxic and antioxidant activities of Monochoria vaginalis.
    Pakistan journal of pharmaceutical sciences, 2011, Volume: 24, Issue:3

    Topics: Acetaminophen; Animals; Antioxidants; Creatine; Disease Models, Animal; Ethanol; Kidney Diseases; Male; Necrosis; Oxidative Stress; Phytotherapy; Plant Components, Aerial; Plant Extracts; Pontederiaceae; Rats; Rats, Wistar; Urea; Uric Acid

2011
Nephroprotective and antioxidant activities of Salacia oblonga on acetaminophen-induced toxicity in rats.
    Natural product research, 2011, Volume: 25, Issue:19

    Topics: Acetaminophen; Animals; Antioxidants; Creatine; Dose-Response Relationship, Drug; Ethanol; Kidney Cortex Necrosis; Plant Extracts; Rats; Salacia; Urea; Uric Acid

2011
Renal function and arterial blood pressure alterations after exposure to acetaminophen with a potential role of Nigella sativa oil in adult male rats.
    Journal of physiology and biochemistry, 2013, Volume: 69, Issue:1

    Topics: Acetaminophen; Administration, Oral; Analgesics; Animals; Arterial Pressure; Biomarkers; Creatinine; Glomerular Filtration Rate; Glutathione Transferase; Isoenzymes; Kidney Tubules, Proximal; Male; Neprilysin; Plant Oils; Proteinuria; Rats; Urea

2013
Integrating cellular metabolism into a multiscale whole-body model.
    PLoS computational biology, 2012, Volume: 8, Issue:10

    Topics: Acetaminophen; Allopurinol; Ammonia; Chemical and Drug Induced Liver Injury; Computational Biology; Computer Simulation; Hepatocytes; Humans; Hyperuricemia; Inactivation, Metabolic; Liver; Metabolism; Models, Biological; Urea; Urea Cycle Disorders, Inborn; Uric Acid

2012
3D organotypic cultures of human HepaRG cells: a tool for in vitro toxicity studies.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 133, Issue:1

    Topics: Acetaminophen; Albumins; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Cell Culture Techniques; Cell Line, Tumor; Chromans; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Hepatocytes; High-Throughput Screening Assays; Humans; Liver; Multidrug Resistance-Associated Protein 2; Rosiglitazone; Spheroids, Cellular; Thiazolidinediones; Toxicity Tests, Acute; Troglitazone; Urea

2013
The relationship between N-acetylcysteine, hyperbaric oxygen, and inflammation in a rat model of acetaminophen-induced nephrotoxicity.
    Inflammation, 2013, Volume: 36, Issue:5

    Topics: Acetaminophen; Acetylcysteine; Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Creatinine; Free Radical Scavengers; Hyperbaric Oxygenation; Inflammation; Interleukin-6; Male; Neopterin; Oxygen; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Urea

2013
Bioactivation and toxicity of acetaminophen in a rat hepatocyte micropatterned coculture system.
    Journal of biochemical and molecular toxicology, 2013, Volume: 27, Issue:10

    Topics: Acetaminophen; Adenosine Triphosphate; Albumins; Analgesics, Non-Narcotic; Animals; Buthionine Sulfoximine; Coculture Techniques; Cytochrome P-450 CYP3A; Dexamethasone; Dose-Response Relationship, Drug; Fibroblasts; Glutathione; Hepatocytes; Male; Models, Biological; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Up-Regulation; Urea

2013
Therapeutic and protective effects of Caesalpinia gilliesii and Cajanus cajan proteins against acetaminophen overdose-induced renal damage.
    Toxicology and industrial health, 2016, Volume: 32, Issue:4

    Topics: Acetaminophen; Acute Kidney Injury; Animals; Cajanus; Creatinine; Fabaceae; Kidney; Male; Plant Extracts; Plant Proteins; Protective Agents; Rats; Rats, Wistar; Seeds; Urea

2016
How useful are clinical liver function tests in in vitro human hepatotoxicity assays?
    Toxicology in vitro : an international journal published in association with BIBRA, 2014, Volume: 28, Issue:5

    Topics: Acetaminophen; Alanine Transaminase; Albumins; Alkaline Phosphatase; Amiodarone; Aspartate Aminotransferases; Biological Assay; Chemical and Drug Induced Liver Injury; gamma-Glutamyltransferase; Hep G2 Cells; Hepatocytes; Humans; L-Lactate Dehydrogenase; Liver Function Tests; Petasites; Plant Extracts; Rifampin; Urea

2014
Therapeutic potential of different commercially available synbiotic on acetaminophen-induced uremic rats.
    Clinical and experimental nephrology, 2015, Volume: 19, Issue:2

    Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Urea Nitrogen; Catalase; Creatinine; DNA Fragmentation; Feces; Glutathione; Kidney Glomerulus; Male; Malondialdehyde; Necrosis; Rats; Rats, Wistar; Superoxide Dismutase; Synbiotics; Urea; Uremia

2015
The use of thymoquinone in nephrotoxicity related to acetaminophen.
    International journal of surgery (London, England), 2015, Volume: 13

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Benzoquinones; Creatinine; Kidney; Male; Rats, Wistar; Urea

2015
Ion-exchange selectivity of diclofenac, ibuprofen, ketoprofen, and naproxen in ureolyzed human urine.
    Water research, 2015, Jan-01, Volume: 68

    Topics: Acetaminophen; Anion Exchange Resins; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Diclofenac; Humans; Hydrogen Bonding; Ibuprofen; Ion Exchange; Ketoprofen; Kinetics; Molecular Structure; Naproxen; Static Electricity; Urea; Waste Disposal, Fluid; Water Pollutants, Chemical

2015
In vitro interference by acetaminophen, aspirin, and metamizole in serum measurements of glucose, urea, and creatinine.
    Clinical biochemistry, 2015, Volume: 48, Issue:7-8

    Topics: Acetaminophen; Aspirin; Biological Assay; Blood Glucose; Creatinine; Dipyrone; Humans; Reproducibility of Results; Urea

2015
Paracetamol-induced nephrotoxicity and oxidative stress in rats: the protective role of Nigella sativa.
    Pharmaceutical biology, 2016, Volume: 54, Issue:10

    Topics: Acetaminophen; Acetylcysteine; Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Creatinine; Cytoprotection; Disease Models, Animal; Ethanol; Female; Glutathione; Kidney; Kidney Diseases; Malondialdehyde; Nigella sativa; Phytotherapy; Plant Extracts; Plants, Medicinal; Rats, Wistar; Seeds; Solvents; Superoxide Dismutase; Urea

2016
AC electrokinetic drug delivery in dentistry using an interdigitated electrode assembly powered by inductive coupling.
    Biomedical microdevices, 2016, Volume: 18, Issue:5

    Topics: Acetaminophen; Benzocaine; Carbamide Peroxide; Carboxylic Acids; Dentistry; Drug Delivery Systems; Electricity; Electrodes; Kinetics; Lidocaine; Microspheres; Motion; Peroxides; Tetracycline; Urea

2016
Maintenance of high quality rat precision cut liver slices during culture to study hepatotoxic responses: Acetaminophen as a model compound.
    Toxicology in vitro : an international journal published in association with BIBRA, 2017, Volume: 42

    Topics: Acetaminophen; Adenosine Triphosphate; Albumins; Animals; Chemical and Drug Induced Liver Injury; Liver; Male; Models, Biological; Organ Culture Techniques; Rats, Wistar; Urea

2017
Solubility, volumetric and compressibility properties of acetaminophen in some aqueous solutions of choline based deep eutectic solvents at T=(288.15 to 318.15) K.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2017, Nov-15, Volume: 109

    Topics: Acetaminophen; Choline; Malonates; Oxalic Acid; Solubility; Solutions; Solvents; Temperature; Thermodynamics; Urea

2017
Adverse Event Trends Associated with OTC Analgesic and Antipyretic Drug: Data Mining of the Japanese Adverse Drug Event Report Database.
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2017, Volume: 137, Issue:10

    Topics: Acetaminophen; Adverse Drug Reaction Reporting Systems; Analgesics; Antipyretics; Data Mining; Databases as Topic; Female; Humans; Japan; Male; Nonprescription Drugs; Time Factors; Urea

2017
Acetaminophen clearance during ex vivo continuous renal replacement therapies.
    Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 2018, Volume: 21, Issue:2

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Cattle; Dialysis Solutions; Hemofiltration; Metabolic Clearance Rate; Renal Dialysis; Urea

2018
Detection of Paracetamol in Water and Urea in Artificial Urine with Gold Nanoparticle@Al Foil Cost-efficient SERS Substrate.
    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2018, Volume: 34, Issue:2

    Topics: Acetaminophen; Aluminum; Biomimetics; Cost-Benefit Analysis; Glass; Gold; Limit of Detection; Metal Nanoparticles; Spectrum Analysis, Raman; Surface Properties; Urea; Water

2018
Nanopillar-Assisted SERS Chromatography.
    ACS sensors, 2018, 12-28, Volume: 3, Issue:12

    Topics: Acetaminophen; Capillary Action; Chromatography; Creatinine; Gold; Humans; Metal Nanoparticles; Microfluidics; Silicon; Spectrum Analysis, Raman; Urea; Uric Acid

2018
Nobiletin attenuates acetaminophen-induced hepatorenal toxicity in rats.
    Journal of biochemical and molecular toxicology, 2020, Volume: 34, Issue:2

    Topics: Acetaminophen; Alanine Transaminase; Animals; Anti-Inflammatory Agents; Antioxidants; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Creatinine; Cytokines; Flavones; Glutathione; Glutathione Peroxidase; Heme Oxygenase (Decyclizing); Kidney; Liver; Male; Malondialdehyde; NF-E2-Related Factor 2; Oxidative Stress; Rats; Rats, Wistar; Urea

2020
Oridonin Alters Hepatic Urea Cycle via Gut Microbiota and Protects against Acetaminophen-Induced Liver Injury.
    Oxidative medicine and cellular longevity, 2021, Volume: 2021

    Topics: Acetaminophen; Animals; Bacteroides; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Diterpenes, Kaurane; Dysbiosis; Fecal Microbiota Transplantation; Gastrointestinal Microbiome; Liver; Male; Metabolome; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Urea

2021
Protective Effect of the Hydroalcoholic Extract of Pelargonium Graveolens L. on Rats with Acetaminophen- Induced Nephrotoxicity.
    Iranian journal of kidney diseases, 2022, Volume: 16, Issue:2

    Topics: Acetaminophen; Animals; Creatinine; Drug-Related Side Effects and Adverse Reactions; Mice; Pelargonium; Plant Extracts; Rats; Urea; Uric Acid

2022
Hepatoprotective effects of walnut oil and Caralluma tuberculata against paracetamol in experimentally induced liver toxicity in mice.
    Acta biochimica Polonica, 2022, Oct-24, Volume: 69, Issue:4

    Topics: Acetaminophen; Animals; Apocynaceae; Body Weight; Cholesterol; Creatinine; Juglans; Liver; Methanol; Mice; Plant Extracts; Triglycerides; Urea

2022
Voltammetric Determination of 3-Methylmorphine Using Glassy Carbon Electrode Modified with rGO and Bismuth Film.
    Biosensors, 2022, Oct-12, Volume: 12, Issue:10

    Topics: Acetaminophen; Ascorbic Acid; Bismuth; Caffeine; Carbon; Cellulose; Chitosan; Electrochemical Techniques; Electrodes; Graphite; Humic Substances; Limit of Detection; Povidone; Silicon Dioxide; Urea; Water

2022
Nephrocurative Effect of Parthenium hysterophorus (Carrot Grass) in Paracetamol Induced Nephrotoxicity in Rabbits.
    Cellular and molecular biology (Noisy-le-Grand, France), 2022, Jul-31, Volume: 68, Issue:7

    Topics: Acetaminophen; Animals; Body Weight; Male; Methanol; Plant Extracts; Poaceae; Rabbits; Urea

2022