acetaminophen has been researched along with urea in 67 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 21 (31.34) | 18.7374 |
1990's | 5 (7.46) | 18.2507 |
2000's | 9 (13.43) | 29.6817 |
2010's | 25 (37.31) | 24.3611 |
2020's | 7 (10.45) | 2.80 |
Authors | Studies |
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Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Avdeef, A; Tam, KY | 1 |
Richens, A | 1 |
Arita, T; Hori, R; Ito, K; Nakano, M; Sekikawa, H | 1 |
el-Banna, HM | 1 |
el-Banna, HM; Gouda, MW; Khalil, SA | 1 |
Clark, EC; Joubert, PH; Otto, AC; Pannall, PR | 1 |
Bindra, DS; Wilson, GS | 1 |
Cockaerts, P | 1 |
Acosta, D; Anuforo, DC; Mitchell, DB; Ramos, K; Santone, KS; Smith, MA; Sorensen, EM | 1 |
Chikasue, F; Kojima, T; Miyazaki, T; Okamoto, I; Yashiki, M | 1 |
Asscher, AW; Elwood, PC; Waters, WE | 1 |
Ando, A; Orita, Y; Shirai, D; Takamitsu, Y; Urakabe, S | 1 |
Nachtigall, C | 1 |
Peters, G | 1 |
Fragen, CA | 1 |
Balme, HW; Berry, H; Hart, FD; Huskisson, EC; Scott, J; Wojtulewski, JA | 1 |
Barraclough, MA; Nilam, F | 1 |
Blendis, LM; Wilkinson, SP; Williams, R | 1 |
Baechtold-Fowler, N; Bonjour, JP; Chométy-Diézi, F; Filloux, B; Guidoux, R; Guignard, JP; Hedinger, C; Peters, G; Peters-Haefeli, L; Roch-Ramel, F; Schelling, JL; Weber, E | 1 |
Barraclough, MA | 1 |
Adjukiewicz, AB; Chalstrey, LJ; Hillenbrand, P; James, IM; Kennedy, J; Parbhoo, SP | 1 |
Carroll, JD; Stephens, JD; Toghill, PJ; Williams, R | 1 |
Burrin, JM; Price, CP; Sylvester, EC | 1 |
Kondo, T; Lin, Z; Nagano, T; Nakaya, T; Nishigami, J; Ohshima, T; Sawaguchi, T; Takayasu, T | 1 |
Kauffman, FC; Pang, JM; Zaleski, J | 1 |
Dalhoff, K; Jensen, SA; Krog, B; Tygstrup, N | 1 |
Berkovitch, M; Chen-Levy, Z; Eshel, G; Koren, G; Lushkov, G; Pinto, O; Reznik, S | 1 |
Brunner, M; Eichler, HG; Erovic, B; Joukhadar, C; Müller, M; Schmid, R | 1 |
Farkas, D; Tannenbaum, SR | 1 |
Abraham, P; Dian, BJ; Kanakasabapathy, I | 1 |
Berg, C; Hengstler, JG; Runge, D; Ullrich, A | 1 |
Chen, C; Gonzalez, FJ; Idle, JR; Krausz, KW | 1 |
Dow, MA; Pettie, JM; Robinson, OD; Stephen, AF; Waring, WS | 1 |
Ray, AR; Ray, P; Verma, P; Verma, V | 1 |
Molinas, SM; Monasterolo, LA; Pagotto, MA; Pisani, GB; Rosso, M; Trumper, L; Wayllace, NZ | 1 |
Ellis, EC; Hengstler, JG; Michalopoulos, GK; Runge, D; Stolz, DB; Strom, SC; Ullrich, A | 1 |
Al-Jabi, SW; Awang, R; Sulaiman, SA; Zyoud, SH | 1 |
Kumar, BS; Kumar, RP; Palani, S; Raja, S; Selvaraj, R | 1 |
Kumar, BS; Kumar, SN; Palani, S; Raja, S | 1 |
Ahmed, OG; El-Mottaleb, NA | 1 |
Borchers, S; Findeisen, R; Krauss, M; Kuepfer, L; Lippert, J; Schaller, S | 1 |
Gunness, P; Heinzle, E; Ingelman-Sundberg, M; Mueller, D; Noor, F; Shevchenko, V | 1 |
Agilli, M; Alp, BF; Altayli, E; Aydin, FN; Aydin, I; Cayci, T; Cermik, H; Ozkan, E; Taslipinar, MY; Toygar, M; Ucar, F | 1 |
Andersen, ME; Aoyama, S; Khetani, SR; Krzyzewski, S; Lecluyse, EL; McVay, M; Rose, K; Ukairo, O | 1 |
Abo-Elmatty, DM; Aly, HF; Desoky, MM; Ibrahim, NA; Rizk, MZ; Younis, EA | 1 |
Borlak, J; Chougule, A; Singh, PK | 1 |
Das, K; Mahapatra, SD; Mahapatra, TD; Mandal, A; Mandal, S; Mondal, KC; Nandi, DK; Patra, A; Paul, T; Roy, S | 1 |
Alabalık, U; Aycan, İÖ; Çelik, F; Evliyaoğlu, O; Güzel, A; Tokgöz, O; Tüfek, A; Turgut, H | 1 |
Boyer, TH; Huang, CH; Landry, KA; Sun, P | 1 |
Cortez-Álvarez, CR; Escutia-Gutiérrez, R; García-Lemus, CR; Luna-Záizar, H; Mendizabal-Ruiz, AP; Ruiz-Quezada, SL; Virgen-Montelongo, M | 1 |
Atmaca, HT; Bayir, Y; Canayakin, D; Halici, Z; Keles, MS; Kilic Baygutalp, N; Kocak Ozgeris, FB; Sezen Karaoglan, E | 1 |
Cheng, C; Gaydarova, R; Ivanoff, CS; Kevorkyan, S; Mirzajani, H; Tomlekova, D; Wu, JJ; Yuan, Q | 1 |
Braun, A; Dasenbrock, C; Granitzny, A; Hansen, T; Knebel, J; Schaudien, D; Steinberg, P | 1 |
Mokhtarpour, M; Shekaari, H; Zafarani-Moattar, MT | 1 |
Abe, J; Fukuda, A; Hasegawa, S; Hatahira, H; Iguchi, K; Kato, Y; Motooka, Y; Naganuma, M; Nakamura, M; Nakao, S; Ohmori, T; Sasaoka, S; Shimauchi, A | 1 |
Annich, GM; Mueller, BA; Scoville, BA; Vulaj, V; Wagner, DS | 1 |
Bukasov, R; Elemessova, Z; Gudun, K; Khamkhash, L; Mukanova, Z; Ralchenko, E | 1 |
Boisen, A; Durucan, O; Rindzevicius, T; Viehrig, M; Wu, K | 1 |
Aksakal, M; Arkalı, G; Cellat, M; Gökçek, İ; Güvenç, M; Özkan, H; Yakan, A; Yurdagül Özsoy, Ş | 1 |
Chen, GH; Chen, SX; Diao, J; Gao, L; Hong, MK; Jia, H; Li, J; Liu, HH; Zhang, DD; Zhao, D; Zheng, SY; Zhu, JQ | 1 |
Akbarpour, B; Asmarian, S; Gholyaf, M; Mohammadi, F | 1 |
Alharbi, M; Ali, W; Alshammari, A; Aziz, T; Iqbal, Z; Jamil, S; Khan, AA; Khan, FF; Shahzad, M; Ur Rahman, S; Zahid, M | 1 |
Baldo, TA; Feitosa, MHA; Moraes, FC; Proença, CA; Santos, AM; Sotomayor, MDPT; Wong, A | 1 |
Ashraf, H; Irfan, M; Khan, WA; Makhdoom, M; Makhdoom, S; Maqbool, A; Muhammad, H | 1 |
Berninzoni, D; D'Alessandro, A; Dylla, L; Hart, C; Heard, KJ; Monte, AA; Pattee, J; Reisz, JA; Vest, A; Wood, C | 1 |
1 review(s) available for acetaminophen and urea
Article | Year |
---|---|
Interactions with antiepileptic drugs.
Topics: Acetaminophen; Acetazolamide; Anti-Anxiety Agents; Anticoagulants; Anticonvulsants; Carbamazepine; Diazepam; Drug Interactions; Furosemide; Gonadal Steroid Hormones; Griseofulvin; Humans; Phenobarbital; Phenytoin; Primidone; Thiazines; Urea; Valproic Acid; Vitamin D | 1977 |
3 trial(s) available for acetaminophen and urea
Article | Year |
---|---|
Treatment of rheumatoid arthritis with fenoprofen: comparison with aspirin.
Topics: Acetaminophen; Arthritis, Rheumatoid; Aspirin; Body Temperature; Clinical Trials as Topic; Deafness; Gastrointestinal Diseases; Humans; Movement; Pain; Placebos; Propionates; Tinnitus; Urea; Uric Acid; Wrist | 1974 |
Effect of vasopressin on the reabsorption of phenacetin and its metabolites from the tubular fluid in man.
Topics: Acetaminophen; Aniline Compounds; Creatinine; Diuresis; Humans; Kidney Papillary Necrosis; Kidney Tubules; Phenacetin; Urea; Vasopressins | 1972 |
A Multi-Omic Mosaic Model of Acetaminophen Induced Alanine Aminotransferase Elevation.
Topics: Acetaminophen; Alanine Transaminase; Chemical and Drug Induced Liver Injury; Genome-Wide Association Study; Humans; Maltose; Multiomics; Urea | 2023 |
63 other study(ies) available for acetaminophen and urea
Article | Year |
---|---|
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Effects of macromolecular additives and urea on the intestinal absorption of acetaminophen in rats.
Topics: Acetaminophen; Animals; Excipients; Intestinal Absorption; Macromolecular Substances; Male; Rats; Urea | 1979 |
Solid dispersion of pharmaceutical ternary systems I: Phase diagram of aspirin-acetaminophen-urea system.
Topics: Acetaminophen; Aspirin; Drug Combinations; Models, Chemical; Thermodynamics; Urea | 1978 |
Solid dispersion of pharmaceutical ternary systems II: Dissolution studies on aspirin-acetaminophen-urea system.
Topics: Acetaminophen; Aspirin; Drug Combinations; Kinetics; Osmolar Concentration; Solubility; Thermodynamics; Urea | 1978 |
Unreliable drug histories, analgesics, and changes in renal function.
Topics: Acetaminophen; Analgesics; Creatinine; Female; Humans; Male; Medical History Taking; Middle Aged; Salicylates; Substance-Related Disorders; Urea | 1977 |
Pulsed amperometric detection of glucose in biological fluids at a surface-modified gold electrode.
Topics: Acetaminophen; Amino Acids; Blood Glucose; Body Fluids; Electrochemistry; Electrodes; Gold; Humans; Urea | 1989 |
[Analysis of Perdolan tablets using high pressure liquid chromatography].
Topics: Acetaminophen; Analgesics; Aspirin; Bromisovalum; Caffeine; Chromatography, High Pressure Liquid; Codeine; Drug Combinations; Pharmaceutical Vehicles; Urea | 1985 |
An in vitro approach to the study of target organ toxicity of drugs and chemicals.
Topics: Acetaminophen; Animals; Antidepressive Agents, Tricyclic; Biotransformation; Cell Survival; Cells, Cultured; Cephaloridine; Heart; Isoproterenol; Kidney Cortex; Lactates; Lactic Acid; Liver; Metals; Myocardial Contraction; Myocardium; Pyruvates; Pyruvic Acid; Rats; Toxicology; Urea | 1985 |
[Extrelut column extraction for screening of drugs in biological materials by gas chromatography and gas chromatography-mass spectrometry--a fatal poisoning by ingestion of a drug containing acetaminophen, ethenzamide and bromvalerylurea].
Topics: Acetaminophen; Adult; Bromisovalum; Chromatography, Gas; Female; Gas Chromatography-Mass Spectrometry; Humans; Salicylamides; Stomach; Suicide; Urea | 1985 |
Community survey of analgesic consumption and kidney function in women.
Topics: Acetaminophen; Adult; Age Factors; Analgesics; Blood Pressure; Chronic Disease; Creatinine; Female; Humans; Kidney; Middle Aged; Phenacetin; Surveys and Questionnaires; Urea; Urinary Tract Infections | 1973 |
Effect of urea derivatives and analgetics on the permeability to water and electrical properties of the urinary bladder of the toad.
Topics: Acetaminophen; Acetanilides; Aminopyrine; Analgesics; Animals; Anura; Biological Transport; Cell Membrane Permeability; Cyclic AMP; Depression, Chemical; Electrophysiology; Epinephrine; Oxyphenbutazone; Phenylbutazone; Stimulation, Chemical; Urea; Urinary Bladder; Vasopressins; Water | 1970 |
[Paidipyrin--a phenacetin free antipyretic for children].
Topics: Acetaminophen; Analgesics; Child; Child, Preschool; Fever; Humans; Infant; Urea | 1967 |
[Analgesia and antipyresis in pediatric orthopedics].
Topics: Acetaminophen; Analgesics; Butyrates; Child; Child, Preschool; Fracture Fixation; Humans; Infant; Orthopedics; Postoperative Care; Preoperative Care; Suppositories; Urea | 1970 |
[Antipyresis in pediatrics].
Topics: Acetaminophen; Analgesics; Child, Preschool; Diphenylacetic Acids; Drug Combinations; Fever; Humans; Infant; Suppositories; Urea | 1972 |
Effect of vasopressin on the renal tubular reabsorption and cortico-papillary concentration gradient of phenacetin and its metabolites.
Topics: Acetaminophen; Animals; Dogs; Female; Kidney; Kidney Concentrating Ability; Kidney Cortex; Kidney Tubules; Phenacetin; Urea; Vasopressins | 1972 |
Frequency and type of renal and electrolyte disorders in fulminant hepatic failure.
Topics: Acetaminophen; Acute Kidney Injury; Blood Glucose; Chemical and Drug Induced Liver Injury; Creatinine; Diuresis; Halothane; Hepatitis A; Hepatitis B; Humans; Kidney Diseases; Liver Diseases; Potassium; Sodium; Urea; Uremia; Water-Electrolyte Balance | 1974 |
General and renal toxicity of phenacetin, paracetamol and some anti-mitotic agents in the rat.
Topics: Acetaminophen; Anemia, Macrocytic; Anilides; Animals; Blood; Blood Glucose; Body Weight; Caffeine; Depression, Chemical; Diuresis; Feeding Behavior; Glomerular Filtration Rate; Growth; Kidney; Male; Mercaptopurine; Methemoglobinemia; Phenacetin; Rats; Urea; Urine | 1972 |
Extracorporeal perfusion of pig liver in the treatment of acute liver failure.
Topics: Acetaminophen; Adult; Animals; Bilirubin; Brain; Chemical and Drug Induced Liver Injury; Electroencephalography; Fatty Liver; Female; Glucose; Hepatic Encephalopathy; Hepatitis A; Hepatitis B; Humans; Liver; Male; Middle Aged; Necrosis; Oxygen Consumption; Perfusion; Radionuclide Imaging; Serum Albumin; Swine; Urea | 1971 |
Acute hepatic necrosis following an overdose of paracetamol.
Topics: Acetaminophen; Acute Disease; Acute Kidney Injury; Adult; Bilirubin; Blood Glucose; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Necrosis; Plasma; Substance-Related Disorders; Suicide; Urea | 1969 |
Investigation of the potential for interference with whole blood glucose strips.
Topics: Acetaminophen; Ascorbic Acid; Blood Chemical Analysis; Blood Glucose; Blood Specimen Collection; Creatinine; Glucose Oxidase; Humans; Hydrogen Peroxide; Oxidation-Reduction; Reagent Strips; Reference Standards; Regression Analysis; Salicylates; Salicylic Acid; Urea; Uric Acid | 1994 |
[A fatal case due to intoxication with seven drugs detected by GC-MS and TDx methods].
Topics: Acetaminophen; Adult; Bromisovalum; Caffeine; Drug Overdose; Female; Fluorescent Antibody Technique; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Ibuprofen; Salicylamides; Suicide; Urea | 1993 |
Actions of selected hepatotoxicants on freshly isolated and cryopreserved rat hepatocytes.
Topics: 1-Propanol; Acetaminophen; Adenosine Triphosphate; Animals; Carbon Tetrachloride; Cell Separation; Cryopreservation; Digitonin; Energy Metabolism; In Vitro Techniques; Liver; Male; Oxygen Consumption; Propanols; Rats; Rats, Sprague-Dawley; Urea | 1996 |
Expression of liver-specific functions in rat hepatocytes following sublethal and lethal acetaminophen poisoning.
Topics: Acetaminophen; Acute-Phase Proteins; Animals; Enzymes; Female; Liver; Liver Regeneration; Proteins; Rats; Rats, Wistar; RNA, Messenger; Urea | 1996 |
The effect of diazepam in the recovery of rabbits from acute acetaminophen intoxication.
Topics: Acetaminophen; Acute Disease; Administration, Oral; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Aspartate Aminotransferases; Creatinine; Diazepam; Drug Evaluation, Preclinical; Male; Rabbits; Survival Rate; Treatment Outcome; Urea | 1999 |
Validation of urea as an endogenous reference compound for the in vivo calibration of microdialysis probes.
Topics: Acetaminophen; Adult; Calibration; Female; Glucose; Humans; Male; Microdialysis; Urea | 2000 |
Characterization of chemically induced hepatotoxicity in collagen sandwiches of rat hepatocytes.
Topics: Acetaminophen; Aflatoxin B1; Albumins; Animals; Benzoquinones; Blotting, Western; Carbon Tetrachloride; Cells, Cultured; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Collagen; Cytochrome P-450 Enzyme System; Dimethylformamide; Glucuronides; Glutathione; Hepatocytes; Isoenzymes; L-Lactate Dehydrogenase; Mass Spectrometry; Oxazines; Rats; Sulfates; Urea; Vinyl Compounds; Xanthenes | 2005 |
Propylthiouracil attenuates acetaminophen-induced renal damage in the rat.
Topics: Acetaminophen; Animals; Creatinine; Dose-Response Relationship, Drug; Kidney; Kidney Diseases; Lipid Peroxides; Male; Propylthiouracil; Rats; Rats, Wistar; Sulfhydryl Compounds; Urea | 2005 |
Use of a standardised and validated long-term human hepatocyte culture system for repetitive analyses of drugs: repeated administrations of acetaminophen reduces albumin and urea secretion.
Topics: Acetaminophen; Albumins; Analgesics, Non-Narcotic; Animal Testing Alternatives; Animals; Cells, Cultured; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Dose-Response Relationship, Drug; Humans; Liver; Urea | 2007 |
Identification of novel toxicity-associated metabolites by metabolomics and mass isotopomer analysis of acetaminophen metabolism in wild-type and Cyp2e1-null mice.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Biomarkers; Cytochrome P-450 CYP2E1; Dose-Response Relationship, Drug; Genotype; Glutathione; Hydrogen Peroxide; Liver; Mass Spectrometry; Mice; Mice, Mutant Strains; Oxidative Stress; Time Factors; Transaminases; Urea | 2008 |
Serum urea concentration and the risk of hepatotoxicity after paracetamol overdose.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Biomarkers; Blood Glucose; Chemical and Drug Induced Liver Injury; Drug Overdose; Epidemiologic Methods; Female; Humans; Male; Urea | 2008 |
Agar-gelatin hybrid sponge-induced three-dimensional in vitro 'liver-like' HepG2 spheroids for the evaluation of drug cytotoxicity.
Topics: Acetaminophen; Agar; Albumins; Analgesics, Non-Narcotic; Cell Culture Techniques; Cell Line; Drug Evaluation, Preclinical; Gelatin; Gene Expression Regulation; Humans; Inhibitory Concentration 50; Kinetics; Liver; Microscopy; Urea | 2009 |
Heat shock protein 70 induction and its urinary excretion in a model of acetaminophen nephrotoxicity.
Topics: Acetaminophen; Acetylglucosaminidase; Analgesics, Non-Narcotic; Animals; Creatinine; Disease Models, Animal; Glutathione; HSP70 Heat-Shock Proteins; Kidney; Kidney Diseases; Kidney Function Tests; Liver; Male; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Urea | 2010 |
Long term cultures of primary human hepatocytes as an alternative to drug testing in animals.
Topics: Acetaminophen; Albumins; Animal Testing Alternatives; Cell Culture Techniques; Culture Media, Serum-Free; Glycogen; Hepatocytes; Humans; L-Lactate Dehydrogenase; Time Factors; Urea | 2009 |
Impact of serum acetaminophen concentration on changes in serum potassium, creatinine and urea concentrations among patients with acetaminophen overdose.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Biomarkers; Child; Child, Preschool; Creatinine; Dose-Response Relationship, Drug; Drug Overdose; Female; Humans; Malaysia; Male; Middle Aged; Potassium; Retrospective Studies; Time Factors; Urea; Young Adult | 2011 |
Evaluation of phytoconstituents and anti-nephrotoxic and antioxidant activities of Monochoria vaginalis.
Topics: Acetaminophen; Animals; Antioxidants; Creatine; Disease Models, Animal; Ethanol; Kidney Diseases; Male; Necrosis; Oxidative Stress; Phytotherapy; Plant Components, Aerial; Plant Extracts; Pontederiaceae; Rats; Rats, Wistar; Urea; Uric Acid | 2011 |
Nephroprotective and antioxidant activities of Salacia oblonga on acetaminophen-induced toxicity in rats.
Topics: Acetaminophen; Animals; Antioxidants; Creatine; Dose-Response Relationship, Drug; Ethanol; Kidney Cortex Necrosis; Plant Extracts; Rats; Salacia; Urea; Uric Acid | 2011 |
Renal function and arterial blood pressure alterations after exposure to acetaminophen with a potential role of Nigella sativa oil in adult male rats.
Topics: Acetaminophen; Administration, Oral; Analgesics; Animals; Arterial Pressure; Biomarkers; Creatinine; Glomerular Filtration Rate; Glutathione Transferase; Isoenzymes; Kidney Tubules, Proximal; Male; Neprilysin; Plant Oils; Proteinuria; Rats; Urea | 2013 |
Integrating cellular metabolism into a multiscale whole-body model.
Topics: Acetaminophen; Allopurinol; Ammonia; Chemical and Drug Induced Liver Injury; Computational Biology; Computer Simulation; Hepatocytes; Humans; Hyperuricemia; Inactivation, Metabolic; Liver; Metabolism; Models, Biological; Urea; Urea Cycle Disorders, Inborn; Uric Acid | 2012 |
3D organotypic cultures of human HepaRG cells: a tool for in vitro toxicity studies.
Topics: Acetaminophen; Albumins; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Cell Culture Techniques; Cell Line, Tumor; Chromans; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Hepatocytes; High-Throughput Screening Assays; Humans; Liver; Multidrug Resistance-Associated Protein 2; Rosiglitazone; Spheroids, Cellular; Thiazolidinediones; Toxicity Tests, Acute; Troglitazone; Urea | 2013 |
The relationship between N-acetylcysteine, hyperbaric oxygen, and inflammation in a rat model of acetaminophen-induced nephrotoxicity.
Topics: Acetaminophen; Acetylcysteine; Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Creatinine; Free Radical Scavengers; Hyperbaric Oxygenation; Inflammation; Interleukin-6; Male; Neopterin; Oxygen; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Urea | 2013 |
Bioactivation and toxicity of acetaminophen in a rat hepatocyte micropatterned coculture system.
Topics: Acetaminophen; Adenosine Triphosphate; Albumins; Analgesics, Non-Narcotic; Animals; Buthionine Sulfoximine; Coculture Techniques; Cytochrome P-450 CYP3A; Dexamethasone; Dose-Response Relationship, Drug; Fibroblasts; Glutathione; Hepatocytes; Male; Models, Biological; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Up-Regulation; Urea | 2013 |
Therapeutic and protective effects of Caesalpinia gilliesii and Cajanus cajan proteins against acetaminophen overdose-induced renal damage.
Topics: Acetaminophen; Acute Kidney Injury; Animals; Cajanus; Creatinine; Fabaceae; Kidney; Male; Plant Extracts; Plant Proteins; Protective Agents; Rats; Rats, Wistar; Seeds; Urea | 2016 |
How useful are clinical liver function tests in in vitro human hepatotoxicity assays?
Topics: Acetaminophen; Alanine Transaminase; Albumins; Alkaline Phosphatase; Amiodarone; Aspartate Aminotransferases; Biological Assay; Chemical and Drug Induced Liver Injury; gamma-Glutamyltransferase; Hep G2 Cells; Hepatocytes; Humans; L-Lactate Dehydrogenase; Liver Function Tests; Petasites; Plant Extracts; Rifampin; Urea | 2014 |
Therapeutic potential of different commercially available synbiotic on acetaminophen-induced uremic rats.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Urea Nitrogen; Catalase; Creatinine; DNA Fragmentation; Feces; Glutathione; Kidney Glomerulus; Male; Malondialdehyde; Necrosis; Rats; Rats, Wistar; Superoxide Dismutase; Synbiotics; Urea; Uremia | 2015 |
The use of thymoquinone in nephrotoxicity related to acetaminophen.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Benzoquinones; Creatinine; Kidney; Male; Rats, Wistar; Urea | 2015 |
Ion-exchange selectivity of diclofenac, ibuprofen, ketoprofen, and naproxen in ureolyzed human urine.
Topics: Acetaminophen; Anion Exchange Resins; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Diclofenac; Humans; Hydrogen Bonding; Ibuprofen; Ion Exchange; Ketoprofen; Kinetics; Molecular Structure; Naproxen; Static Electricity; Urea; Waste Disposal, Fluid; Water Pollutants, Chemical | 2015 |
In vitro interference by acetaminophen, aspirin, and metamizole in serum measurements of glucose, urea, and creatinine.
Topics: Acetaminophen; Aspirin; Biological Assay; Blood Glucose; Creatinine; Dipyrone; Humans; Reproducibility of Results; Urea | 2015 |
Paracetamol-induced nephrotoxicity and oxidative stress in rats: the protective role of Nigella sativa.
Topics: Acetaminophen; Acetylcysteine; Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Creatinine; Cytoprotection; Disease Models, Animal; Ethanol; Female; Glutathione; Kidney; Kidney Diseases; Malondialdehyde; Nigella sativa; Phytotherapy; Plant Extracts; Plants, Medicinal; Rats, Wistar; Seeds; Solvents; Superoxide Dismutase; Urea | 2016 |
AC electrokinetic drug delivery in dentistry using an interdigitated electrode assembly powered by inductive coupling.
Topics: Acetaminophen; Benzocaine; Carbamide Peroxide; Carboxylic Acids; Dentistry; Drug Delivery Systems; Electricity; Electrodes; Kinetics; Lidocaine; Microspheres; Motion; Peroxides; Tetracycline; Urea | 2016 |
Maintenance of high quality rat precision cut liver slices during culture to study hepatotoxic responses: Acetaminophen as a model compound.
Topics: Acetaminophen; Adenosine Triphosphate; Albumins; Animals; Chemical and Drug Induced Liver Injury; Liver; Male; Models, Biological; Organ Culture Techniques; Rats, Wistar; Urea | 2017 |
Solubility, volumetric and compressibility properties of acetaminophen in some aqueous solutions of choline based deep eutectic solvents at T=(288.15 to 318.15) K.
Topics: Acetaminophen; Choline; Malonates; Oxalic Acid; Solubility; Solutions; Solvents; Temperature; Thermodynamics; Urea | 2017 |
Adverse Event Trends Associated with OTC Analgesic and Antipyretic Drug: Data Mining of the Japanese Adverse Drug Event Report Database.
Topics: Acetaminophen; Adverse Drug Reaction Reporting Systems; Analgesics; Antipyretics; Data Mining; Databases as Topic; Female; Humans; Japan; Male; Nonprescription Drugs; Time Factors; Urea | 2017 |
Acetaminophen clearance during ex vivo continuous renal replacement therapies.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Cattle; Dialysis Solutions; Hemofiltration; Metabolic Clearance Rate; Renal Dialysis; Urea | 2018 |
Detection of Paracetamol in Water and Urea in Artificial Urine with Gold Nanoparticle@Al Foil Cost-efficient SERS Substrate.
Topics: Acetaminophen; Aluminum; Biomimetics; Cost-Benefit Analysis; Glass; Gold; Limit of Detection; Metal Nanoparticles; Spectrum Analysis, Raman; Surface Properties; Urea; Water | 2018 |
Nanopillar-Assisted SERS Chromatography.
Topics: Acetaminophen; Capillary Action; Chromatography; Creatinine; Gold; Humans; Metal Nanoparticles; Microfluidics; Silicon; Spectrum Analysis, Raman; Urea; Uric Acid | 2018 |
Nobiletin attenuates acetaminophen-induced hepatorenal toxicity in rats.
Topics: Acetaminophen; Alanine Transaminase; Animals; Anti-Inflammatory Agents; Antioxidants; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Creatinine; Cytokines; Flavones; Glutathione; Glutathione Peroxidase; Heme Oxygenase (Decyclizing); Kidney; Liver; Male; Malondialdehyde; NF-E2-Related Factor 2; Oxidative Stress; Rats; Rats, Wistar; Urea | 2020 |
Oridonin Alters Hepatic Urea Cycle via Gut Microbiota and Protects against Acetaminophen-Induced Liver Injury.
Topics: Acetaminophen; Animals; Bacteroides; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Diterpenes, Kaurane; Dysbiosis; Fecal Microbiota Transplantation; Gastrointestinal Microbiome; Liver; Male; Metabolome; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Urea | 2021 |
Protective Effect of the Hydroalcoholic Extract of Pelargonium Graveolens L. on Rats with Acetaminophen- Induced Nephrotoxicity.
Topics: Acetaminophen; Animals; Creatinine; Drug-Related Side Effects and Adverse Reactions; Mice; Pelargonium; Plant Extracts; Rats; Urea; Uric Acid | 2022 |
Hepatoprotective effects of walnut oil and Caralluma tuberculata against paracetamol in experimentally induced liver toxicity in mice.
Topics: Acetaminophen; Animals; Apocynaceae; Body Weight; Cholesterol; Creatinine; Juglans; Liver; Methanol; Mice; Plant Extracts; Triglycerides; Urea | 2022 |
Voltammetric Determination of 3-Methylmorphine Using Glassy Carbon Electrode Modified with rGO and Bismuth Film.
Topics: Acetaminophen; Ascorbic Acid; Bismuth; Caffeine; Carbon; Cellulose; Chitosan; Electrochemical Techniques; Electrodes; Graphite; Humic Substances; Limit of Detection; Povidone; Silicon Dioxide; Urea; Water | 2022 |
Nephrocurative Effect of Parthenium hysterophorus (Carrot Grass) in Paracetamol Induced Nephrotoxicity in Rabbits.
Topics: Acetaminophen; Animals; Body Weight; Male; Methanol; Plant Extracts; Poaceae; Rabbits; Urea | 2022 |