acetaminophen has been researched along with trimethoprim in 49 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (8.16) | 18.7374 |
1990's | 4 (8.16) | 18.2507 |
2000's | 17 (34.69) | 29.6817 |
2010's | 22 (44.90) | 24.3611 |
2020's | 2 (4.08) | 2.80 |
Authors | Studies |
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Topliss, JG; Yoshida, F | 1 |
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R | 1 |
Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Alimuddin, M; Bulloch, D; Dahl, R; Grant, D; Lee, N; Peacock, M | 1 |
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
Campillo, NE; Guerra, A; Páez, JA | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
Avdeef, A; Tam, KY | 1 |
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Akamatsu, M | 1 |
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Talbot, IC | 1 |
McCormack, JJ; Tong, WP; Webster, LK | 1 |
Bloodworth, L; Christie, JL; Pusey, CD; Rainford, DJ; Saltissi, D | 1 |
Barker, KK; Basmadjian, GP; Hinkle, GH; Ice, RD; Peek, C | 1 |
Chang, M; Riley, CM; Shah, KP | 1 |
Günter, S; Kunkel, A; Wätzig, H | 1 |
Kunkel, A; Wätzig, H | 2 |
Bayazit, H; Ozarmagan, G; Ozkaya-Bayazit, E | 1 |
Brain, RA; Hanson, ML; Johnson, DJ; Lam, MW; Mabury, SA; Richards, SM; Sanderson, H; Sibley, PK; Solomon, KR; Young, C | 1 |
Hasemann, P; ter Balk, M; Wätzig, H | 1 |
Leblanc, A; Roy, R; Shiao, TC; Sleno, L | 1 |
Gilson, R; Henning, JS; Ladd, D; Reese, D; Rockers, K | 1 |
Arizono, K; Matsuo, H; Sakamoto, H; Shinohara, R | 1 |
Chen, F; Chen, H; Fu, W; Luo, W; Meng, F; Xie, Y; Yang, X; Ye, T; Young, K | 1 |
Jeong, CB; Kim, BM; Lee, JS; Lee, YM; Leung, KM; Park, HG; Rhee, JS | 1 |
Gresser, G; Holzgrabe, U; Schollmayer, C; Wiest, J | 1 |
Boncz, MÁ; López-Serna, R; Muñoz, R; Ruas, G; Scarcelli, PG; Serejo, ML | 1 |
Clark, S; Clees, WI; Elkin, KR; Elliott, HA; Hayden, KR; Jones, M; Mashtare, ML; Preisendanz, HE; Read, AF; Richard, TL; Shreve, MJ; Silverman, J; Veith, TL; Watson, JE | 1 |
3 review(s) available for acetaminophen and trimethoprim
Article | Year |
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DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Acute liver injury.
Topics: Acetaminophen; Acute Disease; Chemical and Drug Induced Liver Injury; Cholestasis; Halothane; Hepatitis; Humans; Necrosis; Sulfamethoxazole; Tetracyclines; Trimethoprim | 1975 |
Cyclosporine for SJS/TEN: a case series and review of the literature.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Infective Agents; Anticonvulsants; Cyclosporine; Dermatologic Agents; Drug Combinations; Female; Humans; Lamotrigine; Male; Stevens-Johnson Syndrome; Sulfamethizole; Triazines; Trimethoprim | 2011 |
46 other study(ies) available for acetaminophen and trimethoprim
Article | Year |
---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
QSAR study on permeability of hydrophobic compounds with artificial membranes.
Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship | 2007 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Determination of log D via automated microfluidic liquid-liquid extraction.
Topics: Automation; Biopharmaceutics; Microfluidic Analytical Techniques; Pharmacokinetics | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Importance of physicochemical properties for the design of new pesticides.
Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic | 2011 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Effect of trimethoprim, paracetamol and cimetidine on trimetrexate metabolism by rat perfused isolated livers.
Topics: Acetaminophen; Animals; Cimetidine; Drug Interactions; Folic Acid Antagonists; In Vitro Techniques; Liver; Male; Quinazolines; Rats; Rats, Inbred Strains; Trimethoprim; Trimetrexate | 1987 |
Drug associated acute interstitial nephritis: clinical and pathological features and the response to high dose steroid therapy.
Topics: Acetaminophen; Acute Disease; Adult; Ampicillin; Anti-Infective Agents, Urinary; Bendroflumethiazide; Drug Combinations; Female; Floxacillin; Gentamicins; Humans; Kidney; Male; Methylprednisolone; Middle Aged; Nephritis, Interstitial; Penicillins; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 1983 |
Effects of concurrent drug therapy on technetium Tc-99m gluceptate biodistribution.
Topics: Acetaminophen; Animals; Diagnostic Errors; Drug Interactions; Gallbladder; Humans; Organotechnetium Compounds; Penicillamine; Penicillins; Rabbits; Radionuclide Imaging; Sugar Acids; Sulfamethoxazole; Technetium; Tissue Distribution; Trimethoprim | 1982 |
Automated analytical systems for drug development studies. II--A system for dissolution testing.
Topics: Acetaminophen; Drug Evaluation, Preclinical; Microdialysis; Solubility; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 1994 |
Determination of pharmaceuticals in plasma by capillary electrophoresis without sample pretreatment reproducibility, limit of quantitation and limit of detection.
Topics: Acetaminophen; Buffers; Electrophoresis, Capillary; Humans; Hydrogen-Ion Concentration; Reproducibility of Results; Salicylates; Salicylic Acid; Sodium Dodecyl Sulfate; Sulfamethoxazole; Tolbutamide; Trimethoprim | 1997 |
Pharmacokinetic investigations with direct injection of plasma samples: possible savings using capillary electrophoresis (CE).
Topics: Acetaminophen; Blood Proteins; Drug Monitoring; Electrophoresis, Capillary; Humans; Reproducibility of Results; Salicylic Acid; Sulfamethoxazole; Theophylline; Tolbutamide; Trimethoprim | 1999 |
Micellar electrokinetic capillary chromatography as a powerful tool for pharmacological investigations without sample pretreatment: a precise technique providing cost advantages and limits of detection to the low nanomolar range.
Topics: Acetaminophen; Chromatography, Micellar Electrokinetic Capillary; Costs and Cost Analysis; Humans; Reproducibility of Results; Salicylic Acid; Sulfamethoxazole; Theophylline; Time Factors; Tolbutamide; Trimethoprim | 1999 |
Drug related clinical pattern in fixed drug eruption.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Child; Dimenhydrinate; Dipyrone; Drug Combinations; Drug Eruptions; Female; Histamine H1 Antagonists; Humans; Incidence; Male; Middle Aged; Mucous Membrane; Naproxen; Prospective Studies; Skin; Sulfamethoxazole; Trimethoprim; Turkey | 2000 |
Microcosm evaluation of the effects of an eight pharmaceutical mixture to the aquatic macrophytes Lemna gibba and Myriophyllum sibiricum.
Topics: Acetaminophen; Analysis of Variance; Atorvastatin; Biological Assay; Biomass; Caffeine; Carbamazepine; Complex Mixtures; Dose-Response Relationship, Drug; Heptanoic Acids; Heterocyclic Compounds; Levofloxacin; Magnoliopsida; Ofloxacin; Pharmaceutical Solutions; Pyrroles; Sertraline; Sulfamethoxazole; Toxicity Tests; Trimethoprim; Water Pollutants, Chemical | 2004 |
Analysis of substances to be used as internal standards in MEKC.
Topics: 4-Aminobenzoic Acid; Acetaminophen; Benzocaine; Chromatography, Micellar Electrokinetic Capillary; Ephedrine; Naphthols; Niacin; Pharmaceutical Preparations; Phenol; Reference Standards; Reproducibility of Results; Trimethoprim | 2007 |
Improved detection of reactive metabolites with a bromine-containing glutathione analog using mass defect and isotope pattern matching.
Topics: Acetaminophen; Animals; Bromine Compounds; Chromatography, Liquid; Clozapine; Glutathione; Microsomes, Liver; Pharmaceutical Preparations; Piperazines; Rats; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Trimethoprim | 2010 |
Behavior of pharmaceuticals in waste water treatment plant in Japan.
Topics: Acetaminophen; Amoxicillin; Ampicillin; Carbamazepine; Chromatography, Liquid; Diclofenac; Famotidine; Japan; Ketoprofen; Losartan; Mass Spectrometry; Oseltamivir; Sewage; Trimethoprim; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Purification | 2011 |
Occurrence and fate of PPCPs and correlations with water quality parameters in urban riverine waters of the Pearl River Delta, South China.
Topics: Acetaminophen; Caffeine; Carbamazepine; Carbon; China; Ciprofloxacin; DEET; Environmental Monitoring; Erythromycin; Nitrates; Nitrites; Nitrogen; Pharmaceutical Preparations; Quaternary Ammonium Compounds; Rivers; Sulfamethoxazole; Trimethoprim; Water Pollutants, Chemical; Water Quality | 2013 |
Effect of pharmaceuticals exposure on acetylcholinesterase (AchE) activity and on the expression of AchE gene in the monogonont rotifer, Brachionus koreanus.
Topics: Acetaminophen; Acetylcholinesterase; Amino Acid Sequence; Analgesics, Non-Narcotic; Animals; Anti-Bacterial Agents; Atenolol; Base Sequence; Biocatalysis; Carbamazepine; Chlorpyrifos; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Helminth Proteins; Molecular Sequence Data; Oxytetracycline; Reverse Transcriptase Polymerase Chain Reaction; Rotifera; Sulfamethoxazole; Time Factors; Trimethoprim; Water Pollutants, Chemical; Xenobiotics | 2013 |
Identification and quantitation of the ingredients in a counterfeit Vietnamese herbal medicine against rheumatic diseases.
Topics: Acetaminophen; Chromatography, Liquid; Cinnamomum zeylanicum; Counterfeit Drugs; Herbal Medicine; Indomethacin; Magnetic Resonance Spectroscopy; Mass Spectrometry; Phosphates; Plant Bark; Rheumatic Diseases; Sulfamethoxazole; Trimethoprim; Vietnam | 2014 |
Influence of the hydraulic retention time on the removal of emerging contaminants in an anoxic-aerobic algal-bacterial photobioreactor coupled with anaerobic digestion.
Topics: Acetaminophen; Anaerobiosis; Bacteria, Aerobic; Bioreactors; Ciprofloxacin; Dexamethasone; Enrofloxacin; Ibuprofen; Naproxen; Photobioreactors; Progesterone; Sewage; Sulfamethoxazole; Tetracyclines; Trimethoprim; Tylosin; Waste Disposal, Fluid | 2022 |
Impacts of the COVID-19 pandemic on pharmaceuticals in wastewater treated for beneficial reuse: Two case studies in central Pennsylvania.
Topics: Acetaminophen; Ampicillin; Animals; Anti-Bacterial Agents; COVID-19; Dexamethasone; Doxycycline; Environmental Monitoring; Humans; Hydroxychloroquine; Naproxen; Ofloxacin; Pandemics; Pennsylvania; Pharmaceutical Preparations; Soil; Sulfamethoxazole; Trimethoprim; Waste Disposal, Fluid; Wastewater; Wastewater-Based Epidemiological Monitoring; Water Pollutants, Chemical | 2022 |