acetaminophen has been researched along with triazoles in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.13) | 18.7374 |
| 1990's | 3 (9.38) | 18.2507 |
| 2000's | 6 (18.75) | 29.6817 |
| 2010's | 19 (59.38) | 24.3611 |
| 2020's | 3 (9.38) | 2.80 |
| Authors | Studies |
|---|---|
| Federowicz, DA; Kerns, W; Mico, BA; Ripple, MG | 1 |
| Mugford, CA; Tarloff, JB | 2 |
| Bart, JA; DeLeve, LD; Kaplowitz, N; Shulman, HM; van der Hoek, A; Wang, X | 1 |
| Abbate, E; Deussen, HJ; Duke, K; Galinyte, V; Krikstopaitis, K; Kulys, JJ; Li, K; Schneider, P; Xu, F | 1 |
| Clarke, GD; Godfrey, L; Hourani, SM; Kitchen, I; Ledent, C; Yan, L | 1 |
| Auvin, S; Cuvellier, JC; Joriot, S; Vallée, L | 1 |
| Gano, D; Gerretsen, P; Silver, S | 1 |
| Diamond, M; Diamond, S; Freitag, F; Janssen, I; Rodgers, A; Skobieranda, F | 1 |
| Kalgutkar, AS; Obach, RS; Soglia, JR; Zhao, SX | 1 |
| Abdalla, M; Ghorab, MM; Ismail, ZH | 1 |
| Chavda, M; Clawson, JS; Edwards, AJ; Pham, TN; Strohmeier, M; Vogt, FG; Watson, SA | 1 |
| Chang, S; Dierks, EA; Harper, TW; Marathe, P; Rodrigues, AD; Sun, Q; Zhang, L | 1 |
| Ford, KA | 1 |
| Ember, SW; Mishra, NK; Pomerantz, WC; Schönbrunn, E; Urick, AK | 1 |
| Sakai, F | 1 |
| Kushwah, A; Tomar, A | 1 |
| Isin, EM; Mettetal, JT; Ogese, MO; Thompson, RA; Williams, DP | 1 |
| Berckmans, P; Covaci, A; Hollanders, K; Maho, W; Peers, B; Remy, S; Verstraelen, S; Witters, H | 1 |
| Baillie, TA; Cyrus Khojasteh, S; Dalvie, D; Rietjens, IM | 1 |
| Ejiri, Y; Kotake, Y; Ohta, S; Ohtsuki, Y; Sanoh, S; Santoh, M | 1 |
| Chen, C; Chen, K; Huang, LY; Jin, XT; Li, LL; Lin, GF; Lu, GW; Sun, QZ; Wei, YQ; Xiang, R; Yang, SY; Yang, W; Zhang, G | 1 |
| Copple, IM; Forootan, SS; Francis, B; Goldring, CE; Iwawaki, T; Kipar, A; Mutter, FE; Park, BK | 1 |
| Ko, S; Monga, SP; Poddar, M; Russell, JO; Saggi, HS; Shin, D; Singh, S | 1 |
| Bartoszewicz, M; Król, J; Nawrot, U | 1 |
| Gupta, YK; Holenarsipur, VK; Kaur, H; Mariappan, TT; Padmanabhan, S; Rao, A; Saxena, A | 1 |
| Augustijns, P; Brouwers, J; Mols, R; Rubbens, J | 1 |
| Fan, Q; Hu, W; Hu, X; Huang, W; Ji, Y; Li, X; Li, Y; Lu, X; Pei, F; Tang, Y; Wang, Z; Zhao, H | 1 |
| Abd Eldaim, MA; Abdallah, AEM; Abdel-Daim, MM; Abdelaziz, SAM; Abdul Rashid, S; Abdullah, AS; Abdullah, LC; Abramson, MJ; Ahmed, HB; Ahmed, MM; Ahn, YC; Alexander, DC; Ando, T; Angelone, AM; Anglani, F; Ap, Y; Arthanari, SK; Axelrad, C; Bai, S; Bakonyi, P; Barnes, E; Beckmann, NA; Bélafi-Bakó, K; Bennett, CM; Bestha, RM; Bitsch, RG; Bradley, CA; Bu, Y; Calò, LA; Cañedo-Villaroya, E; Carlson, L; Caruso, S; Casado-Flores, J; Ceol, M; Cesarino, I; Chen, IL; Chen, R; Chen, X; Chilvers, MI; Cho, WK; Choong, TSY; Conceição-Neto, N; Culver, EL; Dai, X; de Lama Caro-Patón, G; De Rosa, I; Del Prete, D; Dharmage, SC; Dimitriadis, E; Dittakavi, S; Dobrowolski, JC; Edin, S; Elgarawany, GE; Emam, HE; Emmens, RW; Erbas, B; Erwich, JJHM; Farghali, M; Feng, L; Funston, RN; Gabler, NK; Gale, P; Ganesh, M; Gao, J; Gao, L; Gao, X; García-Salido, A; Gatto, R; Gautam, S; Ge, C; Ghogomu, SM; Gianesello, L; Gonçales, VR; Gooch, JL; Gooding, JJ; Gourley, GG; Gu, H; Gu, X; Gu, Z; Guerreri, M; Guillén, M; Hazzaa, SM; Heylen, E; Hicks, R; Hong, X; Hoshi, M; Hu, B; Hu, LX; Hu, R; Hu, S; Huang, J; Huang, K; Hubbard, WB; Hui, J; Hwang, NY; Iannacci, J; Ianus, A; Iglesias-Bouzas, MI; Ihara, I; Iwasaki, M; Jaeger, S; Kandel, YR; Karpińska, G; Kim, HK; Klopfenstein, TJ; Knorr, D; Koók, L; Kotb, S; Kruithof, S; Larsson, P; Laurence, C; Leng, J; Li, H; Li, J; Li, Q; Li, S; Li, X; Li, Z; Lian, J; Liang, JX; Liang, X; Lighaam, LC; Lin, CW; Lin, HC; Lin, J; Ling, A; Liu, J; Liu, P; Liu, YS; Ljuslinder, I; Lo, GH; Lodge, CJ; Löfgren-Burström, A; Lowe, AJ; Lu, M; Lu, N; Lucero-Prisno, DE; Luebbe, KM; Luo, X; Ma, Z; Maes, P; Makuch, M; Malekbala, MR; Mao, Z; Martínez-Romera, I; Marzo, G; Mathew, FM; Mattei, A; Matthijnssens, J; Mayumi, M; Morita, N; Mueller, DS; Mullangi, R; Mummolo, S; Murthi, P; Myte, R; Nabeshima, T; Nakamoto, K; Nehdi, IA; Nemestóthy, N; Niessen, HWM; Noh, JM; Nota, A; Nunes, D; Oh, D; Öhlund, D; Olsen, KM; Ono, H; Osawa, Y; Palmqvist, R; Palombo, M; Park, M; Patience, JF; Peng, Y; Perng, DS; Persano, A; Priante, G; Prince, SJ; Pulipati, S; Pyo, H; Qiu, X; Quan, J; Quaranta, F; Quinzi, V; Rademacher, CJ; Rajaraman, G; Rashid, U; Rauch, JC; Rector, A; Remmerswaal, EBM; Ren, R; Rispens, T; Rocha, GS; Saad, NM; Saito, K; Salamova, A; Sarfaraz, K; Satoshi, A; Schnellmann, RG; Scholpa, NE; Schonhoff, M; Schwartz, KJ; Schwarze, M; Schweer, WP; Seiichi, Y; Serrano-González, A; Severino, J; Shemesh, N; Shi, ZQ; Shike, DW; Shim, YM; Siciliano, PA; Siebenrock, KA; Silva, MKL; Smith, DL; Soltani, S; Song, YM; Spry, ML; Stalker, LA; Stokes, RS; Sullivan, PG; Sun, JM; Sun, S; Svanes, C; Syo, K; Tai, CM; Takashima, S; Tashita, C; Taurino, A; Ten Berge, IJM; Tenuta, AU; Teo, SH; Tilley, RD; Trivedi, RK; Umetsu, K; Unger, PA; van Bruggen, R; van Ham, SM; Van Ranst, M; Vanitha, J; Vekaria, HJ; Venier, M; Venkateshwaran, K; Venkert, A; Vermeulen, E; Wan, C; Wang, H; Wang, N; Wang, P; Wang, T; Wang, X; Wang, Y; Wise, KA; Wolbink, GJ; Wu, J; Wu, P; Wu, S; Wu, Y; Xia, Q; Xin, W; Xiong, Q; Xu, H; Xu, P; Xue, S; Yamamoto, Y; Yamashiro, T; Yan, F; Yan, H; Yan, S; Yan, Y; Yang, JM; Yang, L; Yang, P; Ye, W; Yeh, JH; Yinda, CK; Ying, GG; Ying, L; Yoon, HG; Yu, H; Zainuddin, M; Zakkula, A; Zeller, M; Zeng, Y; Zha, J; Zhang, F; Zhang, H; Zhang, M; Zhang, Q; Zhang, S; Zhang, T; Zhang, Z; Zhao, C; Zhao, J; Zhao, Y; Zhong, Q; Zhu, J; Zingmark, C; Zo, JI; Zou, Y | 1 |
| Moghadamnia, AA; Najafpour, G; Nouri, M; Rahimnejad, M | 1 |
| Chan, LN; Chen, KF; Lin, YS | 1 |
| Li, AP; Wei, H | 1 |
5 review(s) available for acetaminophen and triazoles
| Article | Year |
|---|---|
Acute treatment of paediatric migraine: a meta-analysis of efficacy.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; Dihydroergotamine; Drug Evaluation; Humans; Ibuprofen; Migraine Disorders; Oxazolidinones; Placebos; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2008 |
Oral triptans in children and adolescents: an update.
Topics: Acetaminophen; Administration, Oral; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Child; Dose-Response Relationship, Drug; Humans; Migraine Disorders; Randomized Controlled Trials as Topic; Treatment Outcome; Triazoles; Tryptamines; United States; United States Food and Drug Administration | 2015 |
Reactive Metabolites: Current and Emerging Risk and Hazard Assessments.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Antidepressive Agents, Second-Generation; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Pharmaceutical Preparations; Piperazines; Risk Assessment; Triazoles | 2016 |
Biotransformation and bioactivation reactions - 2015 literature highlights.
Topics: Acetaminophen; Allylbenzene Derivatives; Aniline Compounds; Animals; Anisoles; Benzbromarone; Biotransformation; Humans; Imidazoles; Niacinamide; Nitroimidazoles; Nitrosamines; Oxazoles; Oxazolidinones; Peroxides; Pyrazines; Pyrazoles; Pyridazines; Pyridines; Pyridones; Pyrimidinones; Thiophenes; Triazoles | 2016 |
Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Amylose; Anaerobiosis; Animals; Anti-Bacterial Agents; Anura; Arginase; Arthritis, Rheumatoid; Asthma; Atmosphere; B-Lymphocytes; Basic Helix-Loop-Helix Transcription Factors; Bioelectric Energy Sources; Biofilms; Biofuels; Biomarkers; Biopolymers; Bioreactors; Brain; Brain Injuries, Traumatic; Breast Neoplasms; Calibration; Carbon Tetrachloride; Caspase 3; Catalysis; Catechin; Cations; Cattle; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Body; Cell Line, Tumor; Cell Plasticity; Chemical and Drug Induced Liver Injury; Chemistry Techniques, Synthetic; China; Chitosan; Chloride Channels; Chromatography, High Pressure Liquid; Chromosome Mapping; Cognition; Cognitive Dysfunction; Cohort Studies; Colitis, Ulcerative; Colloids; Coloring Agents; Congresses as Topic; Correlation of Data; Crystallization; Cyanoacrylates; Cyclohexane Monoterpenes; Cyprinidae; Cytochrome P-450 CYP1A1; Death, Sudden; Dent Disease; Dietary Supplements; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Disease Progression; Disease Resistance; Disulfides; Drug Monitoring; Drug Stability; Ecotoxicology; Electricity; Electrodes; Endocytosis; Environmental Exposure; Environmental Monitoring; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; Esophageal and Gastric Varices; Esters; Fagopyrum; Female; Ferrosoferric Oxide; Flame Retardants; Flavobacteriaceae; Flow Cytometry; Follow-Up Studies; Formoterol Fumarate; Fusarium; Garlic; Gastrointestinal Hemorrhage; Gene Expression; Genes, Plant; Genetic Markers; Glial Fibrillary Acidic Protein; Gliosis; Global Health; Glutathione Transferase; Glycine max; Gum Arabic; Hemostasis, Endoscopic; Hepatocytes; Hippocampus; Humans; Hydrogen-Ion Concentration; Illinois; Immunoglobulin G; Indoleamine-Pyrrole 2,3,-Dioxygenase; Infant, Newborn; Infant, Small for Gestational Age; Injections, Intraperitoneal; Interleukin-4; Iowa; Iron; Ki-67 Antigen; Kidney; Kinetics; Kynurenine; Lakes; Levofloxacin; Lipid Peroxidation; Lipids; Liver; Liver Cirrhosis, Experimental; Magnetic Fields; Magnetic Iron Oxide Nanoparticles; Male; Manure; Maze Learning; Memory, Short-Term; Metal Nanoparticles; Metals, Heavy; Methane; Mice; Mice, Inbred C57BL; Mice, Knockout; Michigan; Microalgae; Microbial Consortia; Mitochondria; Models, Animal; Models, Chemical; Models, Neurological; Molecular Structure; Molecular Weight; Mutation; Myeloid-Derived Suppressor Cells; NADPH Oxidase 2; Neoplasm Recurrence, Local; Neurites; Neurons; Neuroprotective Agents; NF-kappa B; NIH 3T3 Cells; Nitric Oxide Synthase Type II; Nitrogen; Ohio; Ointments; Ontario; Organelle Biogenesis; Organophosphates; Organophosphorus Compounds; Oxidative Stress; Palladium; Particle Size; Pectins; Phenotype; Phytotherapy; Piperidines; Placenta; Plant Diseases; Plant Extracts; Polymers; Polymorphism, Genetic; Polyphenols; Powders; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Protein Kinase Inhibitors; Protein Structure, Secondary; Proteins; Pyridines; Pyrimidines; Rats, Wistar; Real-Time Polymerase Chain Reaction; Receptors, Aryl Hydrocarbon; Receptors, Chemokine; Receptors, Formyl Peptide; Receptors, Lipoxin; Recovery of Function; Recurrence; Reference Standards; Reference Values; Reproducibility of Results; Respiratory Function Tests; Retrospective Studies; Risk; Sensitivity and Specificity; Sewage; Signal Transduction; Sodium Glutamate; Soil; Solanum tuberosum; Solubility; Solutions; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spermatozoa; STAT3 Transcription Factor; Sulfamethoxazole; Tea; Temperature; Thermodynamics; Thrombin; Treatment Outcome; Triazoles; United States; Viscosity; Waste Disposal, Fluid; Wastewater; Water; Water Pollutants, Chemical; Water Purification; White Matter; Wisconsin; X-Ray Diffraction; Zea mays | 2013 |
3 trial(s) available for acetaminophen and triazoles
| Article | Year |
|---|---|
Efficacy and tolerability of coadministration of rizatriptan and acetaminophen vs rizatriptan or acetaminophen alone for acute migraine treatment.
Topics: Acetaminophen; Acute Disease; Adult; Aged; Analgesics, Non-Narcotic; Double-Blind Method; Drug Therapy, Combination; Drug Tolerance; Female; Humans; Male; Middle Aged; Migraine Disorders; Serotonin Receptor Agonists; Treatment Outcome; Triazoles; Tryptamines; United States | 2008 |
Clinicopharmacological comparative study of rizatriptan versus conventional therapy in migraine.
Topics: Acetaminophen; Adolescent; Adult; Aged; Alprazolam; Analgesics, Non-Narcotic; Female; Flunarizine; Humans; Male; Metoclopramide; Middle Aged; Migraine Disorders; Prospective Studies; Serotonin Receptor Agonists; Treatment Outcome; Triazoles; Tryptamines; Vasodilator Agents; Young Adult | 2014 |
Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Amylose; Anaerobiosis; Animals; Anti-Bacterial Agents; Anura; Arginase; Arthritis, Rheumatoid; Asthma; Atmosphere; B-Lymphocytes; Basic Helix-Loop-Helix Transcription Factors; Bioelectric Energy Sources; Biofilms; Biofuels; Biomarkers; Biopolymers; Bioreactors; Brain; Brain Injuries, Traumatic; Breast Neoplasms; Calibration; Carbon Tetrachloride; Caspase 3; Catalysis; Catechin; Cations; Cattle; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Body; Cell Line, Tumor; Cell Plasticity; Chemical and Drug Induced Liver Injury; Chemistry Techniques, Synthetic; China; Chitosan; Chloride Channels; Chromatography, High Pressure Liquid; Chromosome Mapping; Cognition; Cognitive Dysfunction; Cohort Studies; Colitis, Ulcerative; Colloids; Coloring Agents; Congresses as Topic; Correlation of Data; Crystallization; Cyanoacrylates; Cyclohexane Monoterpenes; Cyprinidae; Cytochrome P-450 CYP1A1; Death, Sudden; Dent Disease; Dietary Supplements; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Disease Progression; Disease Resistance; Disulfides; Drug Monitoring; Drug Stability; Ecotoxicology; Electricity; Electrodes; Endocytosis; Environmental Exposure; Environmental Monitoring; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; Esophageal and Gastric Varices; Esters; Fagopyrum; Female; Ferrosoferric Oxide; Flame Retardants; Flavobacteriaceae; Flow Cytometry; Follow-Up Studies; Formoterol Fumarate; Fusarium; Garlic; Gastrointestinal Hemorrhage; Gene Expression; Genes, Plant; Genetic Markers; Glial Fibrillary Acidic Protein; Gliosis; Global Health; Glutathione Transferase; Glycine max; Gum Arabic; Hemostasis, Endoscopic; Hepatocytes; Hippocampus; Humans; Hydrogen-Ion Concentration; Illinois; Immunoglobulin G; Indoleamine-Pyrrole 2,3,-Dioxygenase; Infant, Newborn; Infant, Small for Gestational Age; Injections, Intraperitoneal; Interleukin-4; Iowa; Iron; Ki-67 Antigen; Kidney; Kinetics; Kynurenine; Lakes; Levofloxacin; Lipid Peroxidation; Lipids; Liver; Liver Cirrhosis, Experimental; Magnetic Fields; Magnetic Iron Oxide Nanoparticles; Male; Manure; Maze Learning; Memory, Short-Term; Metal Nanoparticles; Metals, Heavy; Methane; Mice; Mice, Inbred C57BL; Mice, Knockout; Michigan; Microalgae; Microbial Consortia; Mitochondria; Models, Animal; Models, Chemical; Models, Neurological; Molecular Structure; Molecular Weight; Mutation; Myeloid-Derived Suppressor Cells; NADPH Oxidase 2; Neoplasm Recurrence, Local; Neurites; Neurons; Neuroprotective Agents; NF-kappa B; NIH 3T3 Cells; Nitric Oxide Synthase Type II; Nitrogen; Ohio; Ointments; Ontario; Organelle Biogenesis; Organophosphates; Organophosphorus Compounds; Oxidative Stress; Palladium; Particle Size; Pectins; Phenotype; Phytotherapy; Piperidines; Placenta; Plant Diseases; Plant Extracts; Polymers; Polymorphism, Genetic; Polyphenols; Powders; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Protein Kinase Inhibitors; Protein Structure, Secondary; Proteins; Pyridines; Pyrimidines; Rats, Wistar; Real-Time Polymerase Chain Reaction; Receptors, Aryl Hydrocarbon; Receptors, Chemokine; Receptors, Formyl Peptide; Receptors, Lipoxin; Recovery of Function; Recurrence; Reference Standards; Reference Values; Reproducibility of Results; Respiratory Function Tests; Retrospective Studies; Risk; Sensitivity and Specificity; Sewage; Signal Transduction; Sodium Glutamate; Soil; Solanum tuberosum; Solubility; Solutions; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spermatozoa; STAT3 Transcription Factor; Sulfamethoxazole; Tea; Temperature; Thermodynamics; Thrombin; Treatment Outcome; Triazoles; United States; Viscosity; Waste Disposal, Fluid; Wastewater; Water; Water Pollutants, Chemical; Water Purification; White Matter; Wisconsin; X-Ray Diffraction; Zea mays | 2013 |
25 other study(ies) available for acetaminophen and triazoles
| Article | Year |
|---|---|
In vivo inhibition of oxidative drug metabolism by, and acute toxicity of, 1-aminobenzotriazole (ABT). A tool for biochemical toxicology.
Topics: Acetaminophen; Animals; Antipyrine; Biotransformation; Dogs; Dose-Response Relationship, Drug; Drug Administration Schedule; Male; Oxidation-Reduction; Phenacetin; Rats; Triazoles | 1988 |
Contribution of oxidation and deacetylation to the bioactivation of acetaminophen in vitro in liver and kidney from male and female Sprague-Dawley rats.
Topics: Acetaminophen; Animals; Biotransformation; Carbon Radioisotopes; Female; Kidney; Kidney Diseases; Liver; Male; Nitrophenols; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Sex Factors; Triazoles | 1995 |
Sinusoidal endothelial cells as a target for acetaminophen toxicity. Direct action versus requirement for hepatocyte activation in different mouse strains.
Topics: Acetaminophen; Animals; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Endothelium; Glutathione; Liver; Male; Mice; Mice, Inbred C3H; Species Specificity; Triazoles | 1997 |
The contribution of oxidation and deacetylation to acetaminophen nephrotoxicity in female Sprague-Dawley rats.
Topics: Acetaminophen; Acetylation; Analgesics, Non-Narcotic; Animals; Blood Urea Nitrogen; Female; Glutathione; Kidney; Kidney Diseases; Liver; Male; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Sex Characteristics; Triazoles; Tritolyl Phosphates | 1997 |
Redox chemistry in laccase-catalyzed oxidation of N-hydroxy compounds.
Topics: Acetaminophen; Barbiturates; Biotransformation; Botrytis; Coprinus; Fungi; Hydrogen-Ion Concentration; Kinetics; Laccase; Oxidation-Reduction; Oxidoreductases; Substrate Specificity; Triazoles | 2000 |
Modulation of paracetamol antinociception by caffeine and by selective adenosine A2 receptor antagonists in mice.
Topics: Acetaminophen; Adenosine A2 Receptor Antagonists; Analgesics, Non-Narcotic; Animals; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Female; Male; Mice; Mice, Knockout; Neuroprotective Agents; Nociceptors; Pain; Pain Measurement; Pyrimidines; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Sulfonic Acids; Time Factors; Triazoles; Xanthines | 2006 |
[Medical treatment of migraine attacks in the child].
Topics: Acetaminophen; Age Factors; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Child; Ergot Alkaloids; Humans; Ibuprofen; Life Style; Migraine Disorders; Oxazolidinones; Parents; Patient Education as Topic; Pediatrics; Piperidines; Pyrrolidines; Risk Factors; Serotonin Receptor Agonists; Sumatriptan; Taste Disorders; Triazoles; Tryptamines; Vasoconstrictor Agents | 2006 |
Can in vitro metabolism-dependent covalent binding data in liver microsomes distinguish hepatotoxic from nonhepatotoxic drugs? An analysis of 18 drugs with consideration of intrinsic clearance and daily dose.
Topics: Acetaminophen; Binding Sites; Buspirone; Carbamazepine; Diclofenac; Diphenhydramine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Hepatocytes; Humans; Indomethacin; Meloxicam; Microsomes, Liver; Molecular Structure; Paroxetine; Piperazines; Propranolol; Raloxifene Hydrochloride; Simvastatin; Structure-Activity Relationship; Thiazines; Thiazoles; Ticrynafen; Toxicity Tests; Triazoles | 2008 |
Synthesis and biological activities of some novel triazoloquinazolines and triazinoquinazolines containing benzenesulfonamide moieties.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Edema; Foot; Formaldehyde; Indicators and Reagents; Lethal Dose 50; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Quinazolines; Rats; Rats, Wistar; Spectrophotometry, Infrared; Sulfonamides; Triazines; Triazoles | 2010 |
Analysis of amorphous solid dispersions using 2D solid-state NMR and (1)H T(1) relaxation measurements.
Topics: Acetaminophen; Chemistry, Pharmaceutical; Crystallization; Dextrans; Dosage Forms; Indomethacin; Ketolides; Magnetic Resonance Spectroscopy; Pyrimidines; Solubility; Suspensions; Trehalose; Triazoles; Voriconazole | 2010 |
1-Aminobenzotriazole, a known cytochrome P450 inhibitor, is a substrate and inhibitor of N-acetyltransferase.
Topics: Acetaminophen; Acetylation; Animals; Arylamine N-Acetyltransferase; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Glucuronosyltransferase; Humans; Isoenzymes; Male; Microsomes, Liver; Procainamide; Rats; Rats, Sprague-Dawley; Sulfotransferases; Triazoles; Umbelliferones | 2011 |
Role of electrostatic potential in the in silico prediction of molecular bioactivation and mutagenesis.
Topics: Acetaminophen; Aniline Compounds; Chemistry, Pharmaceutical; Computer Simulation; Cytosine; DNA; Drug Design; Hot Temperature; Imidazoles; Models, Molecular; Mutagenesis; Neonicotinoids; Nitro Compounds; Piperazines; Solubility; Static Electricity; Triazoles; Vinyl Chloride; Water | 2013 |
Fluorinated aromatic amino acids are sensitive 19F NMR probes for bromodomain-ligand interactions.
Topics: Acetaminophen; Amino Acids, Aromatic; Antigens, Nuclear; Azepines; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle Proteins; Crystallography, X-Ray; Cyclic N-Oxides; Escherichia coli; Gene Expression; Halogenation; Humans; Indolizines; Ligands; Magnetic Resonance Spectroscopy; Molecular Docking Simulation; Molecular Probes; Nerve Tissue Proteins; Nuclear Proteins; Oncogene Proteins, Fusion; Protein Binding; Pteridines; Pyridinium Compounds; Pyrrolidines; Recombinant Proteins; Staining and Labeling; Sulfonamides; Transcription Factors; Triazoles | 2014 |
Phenotypic and biomarker evaluation of zebrafish larvae as an alternative model to predict mammalian hepatotoxicity.
Topics: Acetaminophen; Amiodarone; Animals; Apoptosis; Aryl Hydrocarbon Hydroxylases; Ceruloplasmin; Coumarins; Female; Gene Expression Regulation; Genetic Markers; Genome-Wide Association Study; Humans; In Situ Hybridization; Larva; Liver; Male; Methapyrilene; Nitriles; Oxidoreductases, N-Demethylating; Phenotype; Toxicity Tests; Transferrin; Triazoles; Zebrafish; Zebrafish Proteins | 2016 |
Acetaminophen analog N-acetyl-m-aminophenol, but not its reactive metabolite, N-acetyl-p-benzoquinone imine induces CYP3A activity via inhibition of protein degradation.
Topics: Acetaminophen; Acetylcysteine; Animals; Benzoquinones; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Cytochrome P-450 CYP3A Inhibitors; Gene Expression Regulation; Glutathione; Hepatocytes; Imines; Male; Primary Cell Culture; Protein Stability; Proteolysis; Rats; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship; Triazoles | 2017 |
Discovery of Potent and Selective Inhibitors of Cdc2-Like Kinase 1 (CLK1) as a New Class of Autophagy Inducers.
Topics: Acetaminophen; Animals; Autophagy; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Liver; Male; Mice; Mice, Inbred C57BL; Models, Molecular; Protective Agents; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Quinolines; Stereoisomerism; Structure-Activity Relationship; Triazoles | 2017 |
Real-time in vivo imaging reveals localised Nrf2 stress responses associated with direct and metabolism-dependent drug toxicity.
Topics: Acetaminophen; Animals; Cisplatin; Computer Systems; Female; Imaging, Three-Dimensional; Kidney; Liver; Male; Metabolome; Mice, Inbred C57BL; NF-E2-Related Factor 2; Signal Transduction; Stress, Physiological; Triazoles | 2017 |
Bromodomain and Extraterminal (BET) Proteins Regulate Hepatocyte Proliferation in Hepatocyte-Driven Liver Regeneration.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Azepines; Cell Proliferation; Chemical and Drug Induced Liver Injury; Hep G2 Cells; Hepatectomy; Hepatocytes; Humans; Liver Regeneration; Male; Mice; Mice, Inbred C57BL; Proteins; Signal Transduction; Triazoles; Zebrafish | 2018 |
Anti-candidal activity of selected analgesic drugs used alone and in combination with fluconazole, itraconazole, voriconazole, posaconazole and isavuconazole.
Topics: Acetaminophen; Analgesics; Antifungal Agents; Aspirin; Candida; Candida albicans; Candida glabrata; Candidiasis; Dipyrone; Drug Resistance, Fungal; Fluconazole; Humans; Ibuprofen; Itraconazole; Meloxicam; Microbial Sensitivity Tests; Nitriles; Pyridines; Triazoles; Voriconazole | 2018 |
Effect of pretreatment regimens of 1-aminobenzotriazole on metabolism and gastric emptying of probe compounds in rat.
Topics: Acetaminophen; Administration, Oral; Animals; Area Under Curve; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Gastric Emptying; Male; Rats; Rats, Sprague-Dawley; Triazolam; Triazoles | 2019 |
Exploring gastric drug absorption in fasted and fed state rats.
Topics: Acetaminophen; Animals; Diclofenac; Fasting; Gastric Absorption; Gastric Mucosa; Male; Rats, Wistar; Triazoles | 2018 |
Organic semiconducting nanoprobe with redox-activatable NIR-II fluorescence for in vivo real-time monitoring of drug toxicity.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Fluorescent Dyes; Hep G2 Cells; Humans; Maleates; Mice; Nanostructures; Nitric Oxide; Oxidation-Reduction; Polystyrenes; Semiconductors; Spectroscopy, Near-Infrared; Triazoles | 2018 |
Simultaneous voltammetric determination of rizatriptan and acetaminophen using a carbon paste electrode modified with NiFe
Topics: Acetaminophen; Carbon; Electrochemical Techniques; Electrodes; Ferric Compounds; Humans; Limit of Detection; Metal Nanoparticles; Nickel; Oxidation-Reduction; Tablets; Triazoles; Tryptamines | 2020 |
PBPK modeling of CYP3A and P-gp substrates to predict drug-drug interactions in patients undergoing Roux-en-Y gastric bypass surgery.
Topics: Acetaminophen; Administration, Oral; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; Biological Availability; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Digoxin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Gastric Bypass; Gastrointestinal Absorption; Hepatobiliary Elimination; Humans; Intestinal Elimination; Metabolic Clearance Rate; Midazolam; Models, Biological; Obesity, Morbid; Postoperative Period; Triazoles; Verapamil | 2020 |
Permeabilized Cryopreserved Human Hepatocytes as an Exogenous Metabolic System in a Novel Metabolism-Dependent Cytotoxicity Assay for the Evaluation of Metabolic Activation and Detoxification of Drugs Associated with Drug-Induced Liver Injuries: Results w
Topics: Acetaminophen; Activation, Metabolic; Amiodarone; Chemical and Drug Induced Liver Injury; Cyclophosphamide; Cytochrome P-450 Enzyme System; Glutathione; HEK293 Cells; Hepatocytes; Humans; Ketoconazole; Piperazines; Triazoles; Troglitazone | 2022 |