acetaminophen has been researched along with thiophenes in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (7.69) | 18.7374 |
| 1990's | 3 (11.54) | 18.2507 |
| 2000's | 9 (34.62) | 29.6817 |
| 2010's | 11 (42.31) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Duffy, EM; Jorgensen, WL | 1 |
| Mitchell, JR; Potter, WZ | 1 |
| Dybing, E; McMurtry, RJ; Mitchell, JR; Nelson, SD; Thorgeirsson, SS | 1 |
| Atta, NF; Galal, A; Karagözler, AE; Mark, HB; Russell, GC; Zimmer, H | 1 |
| Davies, MH; Schamber, GJ; Schnell, RC | 1 |
| Davies, MH; Schnell, RC | 1 |
| Auyeung, DJ; Kessler, FK; Kessler, MR; Ritter, JK | 1 |
| Cherrington, NJ; Klaassen, CD; Maher, JM; Slitt, AL | 1 |
| Grzesiak, AL; Matzger, AJ; Price, CP | 1 |
| Akcay, A; Bayrak, R; Isik, B; Sogut, S | 1 |
| D'Souza, DN; Iyengar, S; Pritchett, YL; Raskin, J; Tran, P; Waninger, A; Wernicke, JF | 1 |
| Chappell, AS; D'Souza, DN; Iyengar, S; Pritchett, YL; Raskin, J; Smith, TR; Wang, F; Wernicke, JF | 1 |
| Duru, M; Helvaci, R; Kaya, H; Koc, A; Kozlu, T; Kuvandik, G; Nacar, A; Sogüt, S; Yonden, Z | 1 |
| Atta, NF; El-Kady, MF | 1 |
| Erbaş, M; Erkan, ME; Gezer, S; Güneş, H; Kandiş, H; Kara, IH; Yildirim, HA; Yildirim, U | 1 |
| Baltaci, D; Colakoglu, S; Kandis, H; Kara, IH; Karakus, A; Kaya, H; Memisogullari, R; Saritas, A; Yildirim, U | 1 |
| Ciaraldi, TP; Farrell, K; Ghosh, A; Henry, RR; Mudaliar, S; Polidori, D; Rothenberg, P; Sha, S; Vaccaro, N | 1 |
| Scheinfeld, N | 1 |
| Gahn, J; Han, B; Happich, M; Myers, J; Paget, MA; Price, K; Wielage, RC | 1 |
| Choi, DH; Hwang, JH; Kim, KS; Kim, YH; Lee, CH; Noh, JR | 1 |
| Baillie, TA; Cyrus Khojasteh, S; Dalvie, D; Rietjens, IM | 1 |
| Gong, Y; Kumar, S; Rahman, MA | 1 |
| Behrends, V; Bravo-Santano, N; Giskeødegård, GF; Keun, HC; Letek, M | 1 |
| Chang, Y; Hao, B; Li, C; Li, R; Li, Y; Liu, F; Ma, X; Muhammad, I; Shi, C; Wang, F; Yang, Y; Zhang, Y | 1 |
| Fu, F; Li, T; Liu, R; Wang, L; Wang, T; Zhai, R; Zhang, L | 1 |
6 review(s) available for acetaminophen and thiophenes
| Article | Year |
|---|---|
Drug metabolism in the production of liver injury.
Topics: Acetaminophen; Acetanilides; Alkylating Agents; Bromobenzenes; Chemical and Drug Induced Liver Injury; Cyclophosphamide; Drug Hypersensitivity; Ethers; Furosemide; Glutathione; Halothane; Humans; Inactivation, Metabolic; Isoniazid; Liver; Liver Neoplasms; Necrosis; Pharmaceutical Preparations; Phenacetin; Protein Binding; Thiophenes | 1975 |
Metabolic activation: biochemical basis for many drug-induced liver injuries.
Topics: Acetaminophen; Animals; Binding Sites; Carcinogens; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Furosemide; Humans; Hydrazines; Isoniazid; Liver; Methyldopa; Necrosis; Pharmaceutical Preparations; Phenacetin; Thiophenes | 1976 |
Treatment of hidradenitis supprurativa associated pain with nonsteroidal anti-inflammatory drugs, acetaminophen, celecoxib, gabapentin, pegabalin, duloxetine, and venlafaxine.
Topics: Acetaminophen; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclohexanecarboxylic Acids; Cyclohexanols; Drug Therapy, Combination; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Hidradenitis Suppurativa; Humans; Pain; Pain Management; Pregabalin; Pyrazoles; Selective Serotonin Reuptake Inhibitors; Sulfonamides; Thiophenes; Venlafaxine Hydrochloride | 2013 |
The efficacy of duloxetine, non-steroidal anti-inflammatory drugs, and opioids in osteoarthritis: a systematic literature review and meta-analysis.
Topics: Acetaminophen; Administration, Oral; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Bayes Theorem; Drug Evaluation; Duloxetine Hydrochloride; Etoricoxib; Humans; Narcotics; Osteoarthritis; Pain Measurement; Pyridines; Sulfones; Thiophenes; Treatment Outcome | 2014 |
Drugs for osteoarthritis.
Topics: Acetaminophen; Adrenal Cortex Hormones; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Capsaicin; Chondroitin; Dietary Supplements; Duloxetine Hydrochloride; Glucosamine; Humans; Hyaluronic Acid; Injections, Intra-Articular; Osteoarthritis; Thiophenes; Tramadol | 2014 |
Biotransformation and bioactivation reactions - 2015 literature highlights.
Topics: Acetaminophen; Allylbenzene Derivatives; Aniline Compounds; Animals; Anisoles; Benzbromarone; Biotransformation; Humans; Imidazoles; Niacinamide; Nitroimidazoles; Nitrosamines; Oxazoles; Oxazolidinones; Peroxides; Pyrazines; Pyrazoles; Pyridazines; Pyridines; Pyridones; Pyrimidinones; Thiophenes; Triazoles | 2016 |
3 trial(s) available for acetaminophen and thiophenes
| Article | Year |
|---|---|
A randomized controlled trial of duloxetine in diabetic peripheral neuropathic pain.
Topics: Acetaminophen; Adrenergic Uptake Inhibitors; Aged; Analgesics, Non-Narcotic; Diabetic Neuropathies; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Neuralgia; Norepinephrine; Pain; Palliative Care; Peripheral Nervous System Diseases; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Thiophenes; Treatment Outcome | 2006 |
An open-label 52-week clinical extension comparing duloxetine with routine care in patients with diabetic peripheral neuropathic pain.
Topics: Acetaminophen; Amitriptyline; Analgesics; Carbamazepine; Diabetes Complications; Diabetic Neuropathies; Diclofenac; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Lipids; Male; Meloxicam; Middle Aged; Neuralgia; Pentoxifylline; Selective Serotonin Reuptake Inhibitors; Thiamine; Thiazines; Thiazoles; Thioctic Acid; Thiophenes; Time; Vitamin B 12 | 2007 |
Canagliflozin lowers postprandial glucose and insulin by delaying intestinal glucose absorption in addition to increasing urinary glucose excretion: results of a randomized, placebo-controlled study.
Topics: Acetaminophen; Adolescent; Adult; Blood Glucose; Canagliflozin; Cross-Over Studies; Depression, Chemical; Gastric Emptying; Glucose; Glucosides; Glycosuria; Humans; Insulin; Intestinal Absorption; Male; Placebos; Postprandial Period; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2013 |
17 other study(ies) available for acetaminophen and thiophenes
| Article | Year |
|---|---|
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
Electrochemistry and detection of some organic and biological molecules at conducting poly(3-methylthiophene) electrodes.
Topics: Acetaminophen; Aminophenols; Ascorbic Acid; Biosensing Techniques; Catechols; Dopamine; Electrochemistry; Epinephrine; Hydroquinones; Iron; NAD; Polymers; Thiophenes | 1991 |
Oltipraz-induced amelioration of acetaminophen hepatotoxicity in hamsters. I. Lack of dependence on glutathione.
Topics: Acetaminophen; Animals; Cricetinae; Glutathione; Glutathione Disulfide; Liver; Male; Mesocricetus; Oxidation-Reduction; Pyrazines; Schistosomicides; Thiones; Thiophenes | 1991 |
Oltipraz-induced amelioration of acetaminophen hepatotoxicity in hamsters. II. Competitive shunt in metabolism via glucuronidation.
Topics: Acetaminophen; Animals; Cricetinae; Glutathione; Liver; Male; Mesocricetus; Models, Biological; Pyrazines; Schistosomicides; Thiones; Thiophenes; Uridine Diphosphate Glucuronic Acid | 1991 |
Glucuronidation of acetaminophen catalyzed by multiple rat phenol UDP-glucuronosyltransferases.
Topics: Acetaminophen; Analgesics; Animals; Blotting, Western; Catalysis; Cells, Cultured; Chromatography, High Pressure Liquid; Enzyme Induction; Glucuronosyltransferase; Hepatocytes; Humans; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Molecular Sequence Data; Pyrazines; Rats; Rats, Gunn; Rats, Sprague-Dawley; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Thiones; Thiophenes | 2002 |
Induction of multidrug resistance protein 3 in rat liver is associated with altered vectorial excretion of acetaminophen metabolites.
Topics: Acetaminophen; Allyl Compounds; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Bile; Blotting, Western; Branched DNA Signal Amplification Assay; Drug Resistance, Multiple; Kidney; Liver; Male; Mitochondrial Proteins; Phenobarbital; Pyrazines; Rats; Rats, Sprague-Dawley; Ribosomal Proteins; RNA, Messenger; Saccharomyces cerevisiae Proteins; Stilbenes; Sulfides; Thiones; Thiophenes; Time Factors | 2003 |
Crystalline polymorph selection and discovery with polymer heteronuclei.
Topics: Acetaminophen; Carbamazepine; Chemistry, Pharmaceutical; Crystallization; Models, Molecular; Polymers; Spectrum Analysis, Raman; Sulfamethoxazole; Thiophenes; X-Ray Diffraction | 2005 |
Erdosteine against acetaminophen induced renal toxicity.
Topics: Acetaminophen; Animals; Drug Evaluation, Preclinical; Female; Kidney; Kidney Cortex; Kidney Diseases; Kidney Tubules, Proximal; Lipid Peroxidation; Nitric Oxide; Rats; Rats, Wistar; Thioglycolates; Thiophenes | 2006 |
Effects of erdosteine on acetaminophen-induced hepatotoxicity in rats.
Topics: Acetaminophen; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Catalase; Dose-Response Relationship, Drug; Drug Interactions; Female; Glutathione Peroxidase; Liver; Malondialdehyde; Necrosis; Nitric Oxide; Oxidants; Rats; Rats, Wistar; Superoxide Dismutase; Thioglycolates; Thiophenes | 2008 |
Poly(3-methylthiophene)/palladium sub-micro-modified sensor electrode. Part II: Voltammetric and EIS studies, and analysis of catecholamine neurotransmitters, ascorbic acid and acetaminophen.
Topics: Acetaminophen; Ascorbic Acid; Catecholamines; Chemistry Techniques, Analytical; Diffusion; Dopamine; Electric Impedance; Electrochemistry; Electrodes; Electrolytes; Hydrogen-Ion Concentration; Metal Nanoparticles; Neurotransmitter Agents; Palladium; Platinum; Polymers; Thiophenes | 2009 |
Comparison of the effects of N-acetyl cysteine and erdosteine in rats with renal injury caused by paracetamol intoxication.
Topics: Acetaminophen; Acetylcysteine; Acute Kidney Injury; Animals; Antioxidants; Data Interpretation, Statistical; Female; Kidney; Kidney Function Tests; Radionuclide Imaging; Rats; Rats, Wistar; Thioglycolates; Thiophenes | 2011 |
N-Acetyl cysteine and erdosteine treatment in acetaminophen-induced liver damage.
Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Animals; Antidotes; Antipyretics; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Female; International Normalized Ratio; Oxidants; Prothrombin Time; Rats; Rats, Wistar; Thioglycolates; Thiophenes | 2014 |
Enhanced Production of Adenosine Triphosphate by Pharmacological Activation of Adenosine Monophosphate-Activated Protein Kinase Ameliorates Acetaminophen-Induced Liver Injury.
Topics: Acetaminophen; Adenosine Triphosphate; Alanine Transaminase; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspartate Aminotransferases; Biphenyl Compounds; Cells, Cultured; Chemical and Drug Induced Liver Injury; Drug Overdose; Glycolysis; Hepatocytes; Liver; Male; Mice; Mice, Inbred C57BL; Mitochondria, Liver; Necrosis; Phosphorylation; Primary Cell Culture; Pyrones; Thiophenes | 2015 |
In vitro evaluation of structural analogs of diallyl sulfide as novel CYP2E1 inhibitors for their protective effect against xenobiotic-induced toxicity and HIV replication.
Topics: Acetaminophen; Allyl Compounds; Anti-HIV Agents; Cell Survival; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Cytoprotection; Dose-Response Relationship, Drug; Ethanol; Hepatocytes; HIV-1; Humans; Molecular Structure; Structure-Activity Relationship; Sulfides; Thiophenes; U937 Cells; Virus Replication | 2018 |
Acetaminophen cytotoxicity in HepG2 cells is associated with a decoupling of glycolysis from the TCA cycle, loss of NADPH production, and suppression of anabolism.
Topics: Acetaminophen; Cell Survival; Citric Acid Cycle; Drug Synergism; Glutathione; Glycolysis; Hep G2 Cells; Humans; Lactates; Metabolism; Monocarboxylic Acid Transporters; NADP; Pyrimidinones; Symporters; Thiophenes; Toxicity Tests | 2019 |
Acetaminophen-induced hepatocyte injury: C2-ceramide and oltipraz intervention, hepatocyte nuclear factor 1 and glutathione S-transferase A1 changes.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Antioxidants; Cell Culture Techniques; Cell Proliferation; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Gene Expression; Glutathione Transferase; Hep G2 Cells; Hepatocyte Nuclear Factor 1; Hepatocytes; Humans; Pyrazines; Sphingosine; Thiones; Thiophenes | 2019 |
Antinociceptive effects of rotigotine-loaded microspheres and its synergistic interactions with analgesics in inflammatory pain in rats.
Topics: Acetaminophen; Analgesics; Animals; Behavior, Animal; Carrageenan; Delayed-Action Preparations; Disease Models, Animal; Drug Compounding; Drug Synergism; Drug Therapy, Combination; Hyperalgesia; Locomotion; Male; Microspheres; Nociceptive Pain; Open Field Test; Pain Threshold; Rats, Sprague-Dawley; Tetrahydronaphthalenes; Thiophenes; Tramadol | 2021 |