acetaminophen and thioctic acid

acetaminophen has been researched along with thioctic acid in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19902 (13.33)18.7374
1990's0 (0.00)18.2507
2000's3 (20.00)29.6817
2010's10 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dordoni, B; Gazzard, BG; Hughes, RD; Portmann, B; Williams, R1
Schütt, A; Siegers, CP; Strubelt, O1
Christopher, MM; Hill, AS; O'Neill, SL; Rogers, QR1
Chappell, AS; D'Souza, DN; Iyengar, S; Pritchett, YL; Raskin, J; Smith, TR; Wang, F; Wernicke, JF1
Abdel-Hady, RH; Abdel-Zaher, AO; Farrag, MM; Mahmoud, MM1
Ansari, AA; Butler, JD; Coppel, RL; Gershwin, ME; Guggenheim, KG; Kenny, TP; Kurth, MJ; Lam, K; Leung, PS; López-Hoyos, M; Meng, L; Naiyanetr, P; Pfeiff, J; Reiger, R1
Chaparro, LE; Gilron, I; Moore, RA; Wiffen, PJ1
Coppel, RL; Gershwin, ME; Kurth, MJ; Lam, K; Leung, PS1
Ajith, TA; Janardhanan, KK; Sudheesh, NP1
Gershwin, ME; Kenny, TP; Kurth, MJ; Lam, KS; Leung, PS; Naiyanetr, P; Wang, J1
Barakat, W; El-Moselhy, MA; Elshazly, SM1
Daldrup, T; Grass, H; Hadzik, B; Hoehn, T; Mayatepek, E1
Mahmoud, AA; Mahmoud, YI; Nassar, G1
Choi, J; Dubrovsky, AM; Leung, PS; Wang, J; Yang, G1
Abdulrazzaq, AM; Abu Khalil, AA; Alhussainy, TM; Badr, M; Gammoh, O; Ghanim, BY; Qinna, NA1

Reviews

2 review(s) available for acetaminophen and thioctic acid

ArticleYear
Combination pharmacotherapy for the treatment of neuropathic pain in adults.
    The Cochrane database of systematic reviews, 2012, Jul-11, Issue:7

    Topics: Acetaminophen; Adult; Amines; Analgesics; Antidepressive Agents, Tricyclic; Benzodiazepinones; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Morphine; N-Methylaspartate; Neuralgia; Nortriptyline; Phenylurea Compounds; Pregabalin; Thioctic Acid; Tramadol

2012
Xenobiotics and loss of tolerance in primary biliary cholangitis.
    World journal of gastroenterology, 2016, Jan-07, Volume: 22, Issue:1

    Topics: Acetaminophen; Animals; Autoantibodies; Autoantigens; Chemical and Drug Induced Liver Injury; Cholangitis; Dihydrolipoyllysine-Residue Acetyltransferase; Disease Models, Animal; Humans; Immune Tolerance; Mice; Mitochondria; Mitochondrial Proteins; Molecular Mimicry; Thioctic Acid; Xenobiotics

2016

Trials

1 trial(s) available for acetaminophen and thioctic acid

ArticleYear
An open-label 52-week clinical extension comparing duloxetine with routine care in patients with diabetic peripheral neuropathic pain.
    Pain medicine (Malden, Mass.), 2007, Volume: 8, Issue:6

    Topics: Acetaminophen; Amitriptyline; Analgesics; Carbamazepine; Diabetes Complications; Diabetic Neuropathies; Diclofenac; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Lipids; Male; Meloxicam; Middle Aged; Neuralgia; Pentoxifylline; Selective Serotonin Reuptake Inhibitors; Thiamine; Thiazines; Thiazoles; Thioctic Acid; Thiophenes; Time; Vitamin B 12

2007

Other Studies

12 other study(ies) available for acetaminophen and thioctic acid

ArticleYear
Protection of rats against the hepatotoxic effect of paracetamol.
    British journal of experimental pathology, 1974, Volume: 55, Issue:6

    Topics: Acetaminophen; Administration, Oral; Animals; Cysteamine; Cytochrome P-450 Enzyme System; Drug Interactions; Glutathione; Injections, Intraperitoneal; Liver; Male; Microsomes, Liver; Necrosis; Propranolol; Rats; Thioctic Acid; Vitamin E

1974
The curative effects of cysteamine, cysteine, and dithiocarb in experimental paracetamol poisoning.
    Archives of toxicology, 1974, Volume: 33, Issue:1

    Topics: Acetaminophen; Alcohols; Animals; Carboxylic Acids; Chemical and Drug Induced Liver Injury; Cysteamine; Cysteine; Dimercaprol; Enzymes; Flavonoids; Glutathione; Lethal Dose 50; Liver; Male; Mice; Penicillamine; Poisoning; Thiazoles; Thiocarbamates; Thioctic Acid

1974
Effects of dietary antioxidant supplementation before and after oral acetaminophen challenge in cats.
    American journal of veterinary research, 2005, Volume: 66, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetaminophen; Analgesics, Non-Narcotic; Animals; Antioxidants; Biomarkers; Cats; Chromatography, High Pressure Liquid; Cysteine; Dietary Supplements; Drug Therapy, Combination; Female; Glutathione; Guanine; Lymphocyte Activation; Lymphocytes; Male; Methemoglobin; Thioctic Acid; Vitamin E

2005
The potential protective role of alpha-lipoic acid against acetaminophen-induced hepatic and renal damage.
    Toxicology, 2008, Jan-20, Volume: 243, Issue:3

    Topics: Acetaminophen; Administration, Oral; Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Aspartate Aminotransferases; Blood Urea Nitrogen; Chemical and Drug Induced Liver Injury; Creatinine; Dose-Response Relationship, Drug; Glutathione Peroxidase; Kidney; Kidney Diseases; Lipid Peroxidation; Liver; Liver Diseases; Male; Nitrites; Protective Agents; Rats; Rats, Wistar; Survival Rate; Thioctic Acid

2008
Electrophile-modified lipoic derivatives of PDC-E2 elicits anti-mitochondrial antibody reactivity.
    Journal of autoimmunity, 2011, Volume: 37, Issue:3

    Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Autoantibodies; Autoantigens; Autoimmunity; Cattle; Cholangitis; Dihydrolipoyllysine-Residue Acetyltransferase; Enzyme-Linked Immunosorbent Assay; Fatty Acids, Monounsaturated; Humans; Hydrophobic and Hydrophilic Interactions; Liver Cirrhosis, Biliary; Mice; Mitochondria; Mitochondrial Proteins; Protein Structure, Tertiary; Quantitative Structure-Activity Relationship; Serum Albumin; Thioctic Acid

2011
Xenobiotics and autoimmunity: does acetaminophen cause primary biliary cirrhosis?
    Trends in molecular medicine, 2012, Volume: 18, Issue:10

    Topics: Acetaminophen; Animals; Autoantibodies; Autoimmunity; Humans; Liver Cirrhosis, Biliary; Mice; Mitochondria; Pyruvate Dehydrogenase Complex; Quantitative Structure-Activity Relationship; Thioctic Acid; Xenobiotics

2012
Hepatoprotective effects of DL-α-lipoic acid and α-Tocopherol through amelioration of the mitochondrial oxidative stress in acetaminophen challenged rats.
    Toxicology mechanisms and methods, 2013, Volume: 23, Issue:5

    Topics: Acetaminophen; alpha-Tocopherol; Animals; Lipid Peroxidation; Male; Mitochondria; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Thioctic Acid

2013
Environment and primary biliary cirrhosis: electrophilic drugs and the induction of AMA.
    Journal of autoimmunity, 2013, Volume: 41

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Autoantibodies; Binding Sites; Epitopes; Humans; Liver Cirrhosis, Biliary; Models, Immunological; Models, Molecular; Molecular Structure; Protein Binding; Protein Structure, Tertiary; Protein Subunits; Pyruvate Dehydrogenase Complex; Thioctic Acid; Xenobiotics

2013
Insights in the mechanism underlying the protective effect of α-lipoic acid against acetaminophen-hepatotoxicity.
    European journal of pharmacology, 2014, Mar-05, Volume: 726

    Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cytoprotection; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Glutathione; Liver; Male; Malondialdehyde; NF-kappa B; Oxidative Stress; Rats; Rats, Wistar; Thioctic Acid

2014
Fatal non-accidental alpha-lipoic acid intoxication in an adolescent girl.
    Klinische Padiatrie, 2014, Volume: 226, Issue:5

    Topics: Acetaminophen; Adolescent; Anti-Obesity Agents; Antioxidants; Critical Care; Drug Overdose; Fatal Outcome; Female; Humans; Multiple Organ Failure; Octopamine; Suicide, Attempted; Thioctic Acid

2014
Alpha-lipoic acid treatment of acetaminophen-induced rat liver damage.
    Biotechnic & histochemistry : official publication of the Biological Stain Commission, 2015, Volume: 90, Issue:8

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Liver; Male; Rats; Rats, Wistar; Thioctic Acid; Treatment Outcome

2015
Hepatoprotective Actions of Ascorbic Acid, Alpha Lipoic Acid and Silymarin or Their Combination Against Acetaminophen-Induced Hepatotoxicity in Rats.
    Medicina (Kaunas, Lithuania), 2019, May-21, Volume: 55, Issue:5

    Topics: Acetaminophen; Animals; Ascorbic Acid; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Male; Oxidative Stress; Protective Factors; Rats; Rats, Sprague-Dawley; Silymarin; Thioctic Acid

2019