acetaminophen and sulfasalazine

acetaminophen has been researched along with sulfasalazine in 30 studies

Research

Studies (30)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (6.67)	18.7374
1990's	4 (13.33)	18.2507
2000's	9 (30.00)	29.6817
2010's	12 (40.00)	24.3611
2020's	3 (10.00)	2.80

Authors

Authors	Studies
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Haga, K; Kawazoe, Y; Mizuta, H; Ogawa, K	1
Kawazoe, Y; Mizuta, H; Ogawa, K	1
Abadia, R; Christoforov, B; Cremer, GA; Jammet, P	1
Butt, AA; Collier, HO; Gardiner, PJ; Saeed, SA	1
Dunn, RJ	1
Ikegami, K; Ishibashi, T; Kobayashi, M; Kubo, H; Mizobe, M; Yoshino, H	1
Damato, R; Di Poi, E; Favret, G; Ferraccioli, GF; Gremese, E; Tomietto, P	1
Kondo, H; Watanabe, J; Watanabe, T; Yokohama, S	1
Avery, JK	1
Rahman, NU; Woei, WJ; Yuen, KH	1
Förger, F; Østensen, M	1
Amekyeh, H; Billa, N; Chin, SL; Yuen, KH	1
Cai, N; Cheng, K; Liang, H; Wen, J; Xiong, Y; Zhang, W; Zhang, Y; Zhu, J	1
Amekyeh, H; Billa, N	1
Ahmed, K; Khan, I; Mohiuddin, T; Rohman, N; Selvaraj, R; Skelton, AA; Yamin, M	1

Reviews

4 review(s) available for acetaminophen and sulfasalazine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Hepatotoxicity of drugs commonly used in rheumatology]. Annales de medecine interne, 1985, Volume: 136, Issue:7 Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Dextropropoxyphene; Glafenine; Humans; Immunosuppressive Agents; Indoleacetic Acids; Penicillamine; Rheumatic Diseases; Sulfasalazine	1985
Management of RA medications in pregnant patients. Nature reviews. Rheumatology, 2009, Volume: 5, Issue:7 Topics: Abatacept; Acetaminophen; Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antimalarials; Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Contraindications; Cyclosporine; Female; Gestational Age; Glucocorticoids; Humans; Immunoconjugates; Isoxazoles; Leflunomide; Methotrexate; Pregnancy; Pregnancy Complications; Rituximab; Sulfasalazine; Young Adult	2009
The Molecular Mechanisms of Regulating Oxidative Stress-Induced Ferroptosis and Therapeutic Strategy in Tumors. Oxidative medicine and cellular longevity, 2020, Volume: 2020 Topics: Acetaminophen; Antineoplastic Agents; Antioxidants; Apoptosis; Artemisinins; Auranofin; Cell Death; Cisplatin; Epigenesis, Genetic; Fatty Acids; Ferroptosis; Haloperidol; Humans; Indoles; Iron; Lapatinib; Mevalonic Acid; NADP; Neoplasms; Oxidation-Reduction; Oxidative Stress; Oxygen; Quinolines; Reactive Oxygen Species; Sorafenib; Spiro Compounds; Sulfasalazine; Trigonella	2020

Trials

1 trial(s) available for acetaminophen and sulfasalazine

Article	Year
Analysis of improvements, full responses, remission and toxicity in rheumatoid patients treated with step-up combination therapy (methotrexate, cyclosporin A, sulphasalazine) or monotherapy for three years. Rheumatology (Oxford, England), 2002, Volume: 41, Issue:8 Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Cyclosporine; Disease-Free Survival; Drug Therapy, Combination; Female; HLA-DR1 Antigen; Humans; Male; Methotrexate; Middle Aged; Pain; Sulfasalazine	2002

Article

Year

Analysis of improvements, full responses, remission and toxicity in rheumatoid patients treated with step-up combination therapy (methotrexate, cyclosporin A, sulphasalazine) or monotherapy for three years.

Rheumatology (Oxford, England), 2002, Volume: 41, Issue:8

Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Cyclosporine; Disease-Free Survival; Drug Therapy, Combination; Female; HLA-DR1 Antigen; Humans; Male; Methotrexate; Middle Aged; Pain; Sulfasalazine

2002

Other Studies

25 other study(ies) available for acetaminophen and sulfasalazine

Article	Year
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1 Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Effects of meals on gastric emptying and small intestinal transit times of a suspension in the beagle dog assessed using acetaminophen and salicylazosulfapyridine as markers. Chemical & pharmaceutical bulletin, 1990, Volume: 38, Issue:8 Topics: Acetaminophen; Animals; Dogs; Female; Food; Gastric Emptying; Gastrointestinal Transit; Male; Sulfasalazine	1990
Gastrointestinal absorption of chlorothiazide: evaluation of a method using salicylazosulfapyridine and acetaminophen as the marker compounds for determination of the gastrointestinal transit time in the dog. Chemical & pharmaceutical bulletin, 1990, Volume: 38, Issue:10 Topics: Acetaminophen; Animals; Biological Availability; Biomarkers; Chlorothiazide; Dogs; Gastrointestinal Transit; Intestinal Absorption; Male; Sulfasalazine	1990
Proceedings: Effects on prostaglandin biosynthesis of drugs affecting gastrointestinal function. Gut, 1974, Volume: 15, Issue:4 Topics: Acetaminophen; Animals; Aspirin; Cattle; Colchicine; Dexamethasone; Digestive System; Male; Promethazine; Prostaglandins; Quinolines; Rats; Sulfasalazine	1974
Massive sulfasalazine and paracetamol ingestion causing acidosis, hyperglycemia, coagulopathy, and methemoglobinemia. Journal of toxicology. Clinical toxicology, 1998, Volume: 36, Issue:3 Topics: Acetaminophen; Acetylcysteine; Acidosis, Lactic; Acute Disease; Adult; Anti-Inflammatory Agents; Blood Coagulation Disorders; Blood Platelets; Drug Combinations; Drug Overdose; Humans; Hyperglycemia; Infusions, Intravenous; Male; Methemoglobinemia; Methylene Blue; Partial Thromboplastin Time; Sodium Bicarbonate; Suicide, Attempted; Sulfasalazine	1998
Evaluation of colonic absorbability of drugs in dogs using a novel colon-targeted delivery capsule (CTDC). Journal of controlled release : official journal of the Controlled Release Society, 1999, Jun-02, Volume: 59, Issue:3 Topics: Absorption; Acetaminophen; Administration, Oral; Administration, Rectal; Animals; Capsules; Chromatography, High Pressure Liquid; Colon; Dogs; Fasting; Gastric Emptying; In Vitro Techniques; Male; Organ Specificity; Phenylpropanolamine; Sulfasalazine; Theophylline; Time Factors	1999
Effect of food on gastrointestinal transit of liquids in cynomolgus monkeys. Biopharmaceutics & drug disposition, 2003, Volume: 24, Issue:4 Topics: Acetaminophen; Administration, Oral; Animals; Food; Gastric Acidity Determination; Gastric Emptying; Gastrointestinal Transit; Humans; Macaca fascicularis; Male; Models, Animal; Sulfapyridine; Sulfasalazine; Time Factors	2003
Loss prevention case of the month. Monitoring remains critical. Tennessee medicine : journal of the Tennessee Medical Association, 2004, Volume: 97, Issue:1 Topics: Acetaminophen; Agranulocytosis; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Clinical Competence; Diagnostic Errors; Doxepin; Drug Monitoring; Fatal Outcome; Female; Humans; Hydrocodone; Ibuprofen; Indomethacin; Middle Aged; Sulfasalazine; Time Factors; Trimethoprim, Sulfamethoxazole Drug Combination	2004
Gastrointestinal transit monitoring and absorption of controlled-release pellets of diltiazem. Pharmaceutical development and technology, 2005, Volume: 10, Issue:3 Topics: Acetaminophen; Adult; Cecum; Delayed-Action Preparations; Diltiazem; Gastric Emptying; Gastrointestinal Transit; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Male; Solubility; Sulfasalazine	2005
A gastrointestinal transit study on amphotericin B-loaded solid lipid nanoparticles in rats. AAPS PharmSciTech, 2015, Volume: 16, Issue:4 Topics: Acetaminophen; Amphotericin B; Animals; Calorimetry, Differential Scanning; Gastrointestinal Transit; Lipids; Microscopy, Electron, Scanning; Nanoparticles; Rats; Sulfasalazine	2015
Lyophilized Drug-Loaded Solid Lipid Nanoparticles Formulated with Beeswax and Theobroma Oil. Molecules (Basel, Switzerland), 2021, Feb-09, Volume: 26, Issue:4 Topics: Acetaminophen; Amphotericin B; Cacao; Drug Carriers; Drug Compounding; Freeze Drying; Hydrophobic and Hydrophilic Interactions; Lipids; Nanoparticles; Pharmaceutical Preparations; Plant Oils; Sulfasalazine; Waxes	2021
Theoretical insights and implications of pH-dependent drug delivery systems using silica and carbon nanotube. Journal of molecular graphics & modelling, 2023, Volume: 125 Topics: Acetaminophen; Alendronate; Drug Delivery Systems; Hydrogen-Ion Concentration; Ibuprofen; Nanotubes, Carbon; Quartz; Silicon Dioxide; Sulfasalazine	2023