acetaminophen and sorbitol

acetaminophen has been researched along with sorbitol in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19904 (20.00)18.7374
1990's6 (30.00)18.2507
2000's4 (20.00)29.6817
2010's6 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Alvarez, A; Chávez, M; Chávez-Anaya, E; Medina, C; Medina, MD; Mendoza, R; Ramírez, MG; Sáenz, G; Vaca, G; Vargas, M1
Blakytny, R; Harding, JJ1
Eyer, P; Sprenger, M1
Esezobo, S1
Odom, JD; Williams, WF1
Aaron, CK; Davidheiser, S; Gemborys, M; McNamara, RM1
Walters, V1
Curzon, ME; Marathaki, E; Pollard, MA1
Alpert, D; Schwenger, P; Skolnik, EY; Vilcek, J1
Sonnergaard, JM1
Kawasaki, N; Matsumoto, K; Nakamura, T; Oida, Y; Tanada, S1
Attwood, D; Fujiwara, M; Itoh, K; Kubo, W; Miyazaki, S; Watanabe, H1
Ito, A; Machida, Y; Yamamoto, K1
Attwood, D; D'Emanuele, A; Hatakeyama, T; Itoh, K; Kimura, T; Miyazaki, S; Shimoyama, T1
Pisklak, DM; Szeleszczuk, Ł; Zielińska-Pisklak, M1

Reviews

1 review(s) available for acetaminophen and sorbitol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for acetaminophen and sorbitol

ArticleYear
Sorbitol catharsis does not enhance efficacy of charcoal in a simulated acetaminophen overdose.
    Annals of emergency medicine, 1988, Volume: 17, Issue:3

    Topics: Acetaminophen; Adolescent; Adult; Cathartics; Charcoal; Drug Therapy, Combination; Humans; Male; Random Allocation; Solutions; Sorbitol

1988

Other Studies

18 other study(ies) available for acetaminophen and sorbitol

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Effects of G-6-PD deficiency, experimentally induced or genetically transmitted, on the sorbitol pathway activity. In vitro and in vivo studies.
    Archives of medical research, 1992,Spring, Volume: 23, Issue:1

    Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Aldehyde Reductase; Animals; Black People; Cataract; Child; Chloramphenicol; Costa Rica; Dehydroepiandrosterone; Diabetes Complications; Diabetes Mellitus; Disease Models, Animal; Erythrocytes; Galactosemias; Glucosephosphate Dehydrogenase; Glucosephosphate Dehydrogenase Deficiency; Humans; Incidence; L-Iditol 2-Dehydrogenase; Lens, Crystalline; Male; Middle Aged; NADP; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Sorbitol

1992
Glycation (non-enzymic glycosylation) inactivates glutathione reductase.
    The Biochemical journal, 1992, Nov-15, Volume: 288 ( Pt 1)

    Topics: Acetaminophen; Animals; Aspirin; Cattle; Fructose; Glucose; Glucose-6-Phosphate; Glucosephosphates; Glutathione Reductase; Glycosylation; Hydrogen-Ion Concentration; Ibuprofen; Intestines; Kinetics; Sorbitol

1992
[Oral administration of activated charcoal-sorbitol suspension as first aid in prevention of poison resorption?].
    Klinische Wochenschrift, 1991, Nov-26, Volume: 69, Issue:19

    Topics: Acetaminophen; Charcoal; Codeine; Diphenhydramine; Drug Overdose; Humans; Intestinal Absorption; Metabolic Clearance Rate; Patient Acceptance of Health Care; Sorbitol

1991
The effect of some excipients on the physical properties of a paracetamol tablet formulation.
    The Journal of pharmacy and pharmacology, 1985, Volume: 37, Issue:3

    Topics: Acetaminophen; Drug Compounding; Excipients; Hardness; Powders; Silicon Dioxide; Sodium Dodecyl Sulfate; Solubility; Sorbitol; Stearic Acids; Tablets

1985
Study of aldose reductase inhibition in intact lenses by 13C nuclear magnetic resonance spectroscopy.
    Science (New York, N.Y.), 1986, Jul-11, Volume: 233, Issue:4760

    Topics: Acetaminophen; Aldehyde Reductase; Animals; Ibuprofen; Imidazoles; Imidazolidines; Lens, Crystalline; Magnetic Resonance Spectroscopy; Naphthalenes; Organ Culture Techniques; Rabbits; Sorbitol; Sugar Alcohol Dehydrogenases

1986
The dissolution of paracetamol tablets and the in vitro transfer of paracetamol with and without sorbitol.
    The Journal of pharmacy and pharmacology, 1968, Volume: 20

    Topics: Acetaminophen; Intestinal Absorption; Models, Biological; Solubility; Sorbitol; Tablets

1968
The effect of sucrose in medicines on plaque pH.
    International journal of paediatric dentistry, 1995, Volume: 5, Issue:4

    Topics: Acetaminophen; Adult; Amoxicillin; Analysis of Variance; Child, Preschool; Dental Care for Children; Dental Plaque; Diphenhydramine; Drug Compounding; Female; Humans; Hydrogen-Ion Concentration; Male; Pharmaceutical Vehicles; Sorbitol; Statistics, Nonparametric; Sucrose; Sweetening Agents

1995
Cell-type-specific activation of c-Jun N-terminal kinase by salicylates.
    Journal of cellular physiology, 1999, Volume: 179, Issue:1

    Topics: Acetaminophen; Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calcium-Calmodulin-Dependent Protein Kinases; Chlorocebus aethiops; Colonic Neoplasms; COS Cells; Cyclooxygenase Inhibitors; Enzyme Activation; Epidermal Growth Factor; Fibroblasts; Humans; Hypertonic Solutions; Ibuprofen; Indomethacin; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; NF-kappa B; Organ Specificity; Osmotic Pressure; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-jun; Recombinant Fusion Proteins; Saline Solution, Hypertonic; Signal Transduction; Sodium Salicylate; Sorbitol; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1999
A critical evaluation of the Heckel equation.
    International journal of pharmaceutics, 1999, Dec-20, Volume: 193, Issue:1

    Topics: Acetaminophen; Ascorbic Acid; Cellulose; Chemistry, Pharmaceutical; Densitometry; Models, Theoretical; Powders; Pressure; Regression Analysis; Sodium Chloride; Sorbitol; Tablets

1999
Inhibitory effect of sorbitol on acetaminophen adsorption by activated carbon.
    Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 2002, Volume: 37, Issue:5

    Topics: Acetaminophen; Administration, Oral; Adsorption; Analgesics, Non-Narcotic; Cathartics; Charcoal; Drug Interactions; Humans; Particle Size; Sorbitol; Temperature

2002
The influence of gastric acidity and taste masking agent on in situ gelling pectin formulations for oral sustained delivery of acetaminophen.
    Biological & pharmaceutical bulletin, 2006, Volume: 29, Issue:2

    Topics: Acetaminophen; Administration, Oral; Animals; Biological Availability; Delayed-Action Preparations; Drug Compounding; Excipients; Gastric Acid; Gastric Mucosa; Gels; Hydrogen-Ion Concentration; Male; Pectins; Rabbits; Solubility; Sorbitol; Taste

2006
Preparation and evaluation of medicinal carbon tablets with different saccharides as binders.
    Chemical & pharmaceutical bulletin, 2009, Volume: 57, Issue:10

    Topics: Acetaminophen; Adsorption; Analgesics, Non-Narcotic; Carbon; Drug Compounding; Maltose; Mannitol; Sorbitol; Sugar Alcohols; Tablets; Xylitol

2009
Effect of D-sorbitol on the thermal gelation of methylcellulose formulations for drug delivery.
    Chemical & pharmaceutical bulletin, 2010, Volume: 58, Issue:2

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Delayed-Action Preparations; Diffusion; Gels; Methylcellulose; Sorbitol; Temperature

2010
Application of
    International journal of pharmaceutics, 2016, Nov-20, Volume: 513, Issue:1-2

    Topics: Acetaminophen; Carbazoles; Carbon-13 Magnetic Resonance Spectroscopy; Carvedilol; Cellulose; Dosage Forms; Excipients; Propanolamines; Sorbitol

2016