acetaminophen and rofecoxib

acetaminophen has been researched along with rofecoxib in 56 studies

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's50 (89.29)29.6817
2010's6 (10.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andricopulo, AD; Moda, TL; Montanari, CA1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bird, SR; Bohidar, NR; Chang, DJ; Dobbins, TW; Fricke, JR; Geba, GP1
Catella-Lawson, F; Cucchiara, AJ; DeMarco, S; FitzGerald, GA; Kapoor, SC; Reilly, MP; Tournier, B; Vyas, SN1
Dixon, ME; Geba, GP; Polis, AB; Schnitzer, TJ; Weaver, AL1
McColl, GJ1
Bridge, HS; Nolan, J; Pickering, AE; Stoddart, PA1
Berger, MY; Bierma-Zeinstra, SM; Bohnen, AM; Thomas, S1
Henderson, P1
Day, RO; Graham, GG; Graham, RI1
Hu, J; Ing, C; Issioui, T; Jones, SB; Klein, KW; Marple, BF; Skrivanek, GD; Watcha, MF; White, PF1
Issioui, T; Klein, KW; Watcha, MF; White, PF1
Connelly, NR; Joshi, W; Reuben, SS; Thakkar, N; Wolckenhaar, M1
Chow, KM; Lai, FM; Li, P; Szeto, CC1
Castello, JV; de Mateo, JA; Enrique, E; Malek, T; Roca, B; Rodríguez, M1
Emkey, R; Jordan, D; Kamin, M; Rosenthal, N; Wu, SC1
Shintani, EY; Skinner, HB1
Bird, SR; Black, P; Chang, DJ; Chen, E; Desjardins, PJ; Geba, GP; Petruschke, RA1
Fricke, JR; Korn, S; Kotey, PN; Vassil, TC1
Battisti, WP; Geba, GP; Katz, NP; Kivitz, AJ; Matsumoto, AK; Polis, AB; Weaver, AL1
Almekinders, LC; Rahusen, FT; Weinhold, PS1
Lizán Tudela, L; Magaz Marqués, S; Riesgo Bucher, Y; Varela Moreno, C1
Liu, W; Loo, CC; Ren, HZ; Tan, HM; Ye, TH1
Lucas, R; Mitchell, JA; Vojnovic, I; Warner, TD1
Afshari, HM; Dahners, LE; Hanson, CA; Weinhold, PS1
Geba, GP; Petruschke, RA; Polis, AB; Schnitzer, TJ; Weaver, AL1
Asero, R2
Bird, SR; Bohidar, NR; Chang, DJ; King, T1
Ammar, MM; Gilbert, JG; Khrapov, AV; McClintock, A; Naesh, O; Niles, LA; Phibbs, PW; Phillips, AM; Robert, AJ1
Cadeddu, JA; Duchene, D; Johnson, DB; Recart, A; Thomas, T; White, PF1
Aeschlimann, A; Gay, RE; Gay, S; Michel, BA; Shen, H; Sprott, H1
Church, CA; O-Lee, TJ; Stewart, C; Wallace, D1
Bountra, C; Chessell, IP; Day, NC; Staton, PC; Wilson, AW1
Cağici, CA; Calişkan, EE; Erkan, AN; Gencay, S; Ozlüoğlu, LN; Sener, M; Yavuz, H; Yilmaz, I; Yilmazer, C1
Haglund, B; von Bültzingslöwen, I1
Alleyne, CH; French, A; Macomson, SD; Rahimi, SY; Smith, JR; Vender, JR1
Chelly, JE; Nissen, CW; Rodgers, AJ; Smugar, SS; Tershakovec, AM1
Nedjar, H; Rahme, E1
Barozzi, N; Tett, SE2
Bird, SR; Black, PM; Chang, DJ; Daniels, SE; Desjardins, PJ; Petruschke, RA; Smugar, SS; Tershakovec, AM1
Bean-Lijewski, JD; Browne, B; Hutchinson, L; Kruitbosch, SH1
Carignan, M; Dorion, D; Lafrenaye, S; Vallée, E1
Brahim, JS; Chuang, BP; Dionne, RA; Gordon, SM; Hamza, MA; Rowan, JS; Wang, XM1
Altman, RD; Cooper, KM; Schnitzer, TJ; Tesser, JR1
Ashok, V; Dash, C; Rohan, TE; Sprafka, JM; Terry, PD1
McGettigan, P; Waring, WS1

Reviews

3 review(s) available for acetaminophen and rofecoxib

ArticleYear
Pharmacological therapies for the treatment of osteoarthritis.
    The Medical journal of Australia, 2001, 11-19, Volume: 175, Issue:S3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Celecoxib; Cyclooxygenase Inhibitors; Humans; Lactones; Pyrazoles; Sulfonamides; Sulfones

2001
Comparative analgesia, cardiovascular and renal effects of celecoxib, rofecoxib and acetaminophen (paracetamol).
    Current pharmaceutical design, 2002, Volume: 8, Issue:12

    Topics: Acetaminophen; Analgesia; Cardiovascular System; Celecoxib; Clinical Trials as Topic; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Isoenzymes; Kidney; Lactones; Liver; Membrane Proteins; Osteoarthritis; Pain; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Sulfones

2002
[Analysis of cost-minimization treatment with paracetamol or COX-2 inhibitors (rofecoxib) for pain from arthrosis of the knee or hip].
    Atencion primaria, 2004, Volume: 34, Issue:10

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Costs and Cost Analysis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Decision Trees; Hip Joint; Humans; Joint Diseases; Knee Joint; Lactones; Membrane Proteins; Pain; Prostaglandin-Endoperoxide Synthases; Severity of Illness Index; Sulfones

2004

Trials

29 trial(s) available for acetaminophen and rofecoxib

ArticleYear
Rofecoxib versus codeine/acetaminophen in postoperative dental pain: a double-blind, randomized, placebo- and active comparator-controlled clinical trial.
    Clinical therapeutics, 2001, Volume: 23, Issue:9

    Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Codeine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrocodone; Lactones; Male; Pain Measurement; Pain, Postoperative; Sulfones; Time Factors; Tooth Extraction; Treatment Outcome

2001
Cyclooxygenase inhibitors and the antiplatelet effects of aspirin.
    The New England journal of medicine, 2001, Dec-20, Volume: 345, Issue:25

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Drug Interactions; Drug Therapy, Combination; Humans; Ibuprofen; Isoenzymes; Lactones; Membrane Proteins; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Sulfones; Thromboxane B2

2001
Efficacy of rofecoxib, celecoxib, and acetaminophen in osteoarthritis of the knee: a randomized trial.
    JAMA, 2002, Jan-02, Volume: 287, Issue:1

    Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Humans; Isoenzymes; Lactones; Male; Membrane Proteins; Middle Aged; Osteoarthritis, Knee; Pain Measurement; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Sulfones

2002
Double-blind, placebo-controlled analgesic study of ibuprofen or rofecoxib in combination with paracetamol for tonsillectomy in children.
    British journal of anaesthesia, 2002, Volume: 88, Issue:1

    Topics: Acetaminophen; Adenoidectomy; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Blood Loss, Surgical; Child; Child, Preschool; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ibuprofen; Infant; Lactones; Male; Pain, Postoperative; Premedication; Sulfones; Tonsillectomy

2002
Cost-efficacy of rofecoxib versus acetaminophen for preventing pain after ambulatory surgery.
    Anesthesiology, 2002, Volume: 97, Issue:4

    Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cost-Benefit Analysis; Costs and Cost Analysis; Double-Blind Method; Female; Humans; Lactones; Male; Middle Aged; Otorhinolaryngologic Surgical Procedures; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Postoperative Nausea and Vomiting; Sulfones

2002
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery.
    Anesthesia and analgesia, 2003, Volume: 96, Issue:4

    Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxib; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Humans; Lactones; Male; Middle Aged; Otorhinolaryngologic Surgical Procedures; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Postoperative Nausea and Vomiting; Pyrazoles; Sulfonamides; Sulfones

2003
An evaluation of the safety and efficacy of administering rofecoxib for postoperative pain management.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Codeine; Female; Hemorrhage; Humans; Lactones; Male; Pain Measurement; Pain, Postoperative; Postoperative Complications; Sulfones; Tonsillectomy

2003
Efficacy and safety of tramadol/acetaminophen tablets (Ultracet) as add-on therapy for osteoarthritis pain in subjects receiving a COX-2 nonsteroidal antiinflammatory drug: a multicenter, randomized, double-blind, placebo-controlled trial.
    The Journal of rheumatology, 2004, Volume: 31, Issue:1

    Topics: Acetaminophen; Aged; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Combinations; Female; Humans; Lactones; Male; Middle Aged; Narcotics; Osteoarthritis; Pain; Placebos; Pyrazoles; Sulfonamides; Sulfones; Tramadol; Treatment Outcome

2004
Comparison of rofecoxib and a multidose oxycodone/ acetaminophen regimen for the treatment of acute pain following oral surgery: a randomized controlled trial.
    Current medical research and opinion, 2004, Volume: 20, Issue:6

    Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lactones; Male; Oxycodone; Pain; Placebos; Sulfones; Surgery, Oral; Treatment Outcome

2004
Comparison of rofecoxib and oxycodone plus acetaminophen in the treatment of acute pain: a randomized, double-blind, placebo-controlled study in patients with moderate to severe postoperative pain in the third molar extraction model.
    Clinical therapeutics, 2004, Volume: 26, Issue:5

    Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug Combinations; Female; Humans; Lactones; Male; Oxycodone; Pain, Postoperative; Sulfones; Tooth Extraction

2004
Pain management in osteoarthritis: a focus on onset of efficacy--a comparison of rofecoxib, celecoxib, acetaminophen, and nabumetone across four clinical trials.
    The journal of pain, 2004, Volume: 5, Issue:9

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Butanones; Celecoxib; Humans; Lactones; Nabumetone; Osteoarthritis, Knee; Pyrazoles; Sulfonamides; Sulfones; Treatment Outcome

2004
[Comparison of preemptive analgesia efficacy between etoricoxib and rofecoxib in ambulatory gynecological surgery].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2004, Volume: 26, Issue:6

    Topics: Abortion, Induced; Acetaminophen; Adolescent; Adult; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Cyclooxygenase Inhibitors; Double-Blind Method; Etoricoxib; Female; Fentanyl; Humans; Lactones; Pain Measurement; Pain, Postoperative; Preoperative Care; Pyridines; Sulfones

2004
Efficacy of rofecoxib, celecoxib, and acetaminophen in patients with osteoarthritis of the knee. A combined analysis of the VACT studies.
    The Journal of rheumatology, 2005, Volume: 32, Issue:6

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Celecoxib; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Lactones; Male; Middle Aged; Osteoarthritis, Knee; Pain; Pain Measurement; Pyrazoles; Severity of Illness Index; Sulfonamides; Sulfones; Treatment Outcome

2005
Oral aspirin challenges in patients with a history of intolerance to single non-steroidal anti-inflammatory drugs.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2005, Volume: 35, Issue:6

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Cyclooxygenase Inhibitors; Drug Evaluation; Female; Humans; Lactones; Male; Middle Aged; ortho-Aminobenzoates; Recurrence; Single-Blind Method; Sulfonamides; Sulfones; Tramadol; Urticaria

2005
Analgesic efficacy of rofecoxib compared with codeine/acetaminophen using a model of acute dental pain.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2005, Volume: 100, Issue:4

    Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Variance; Codeine; Consumer Product Safety; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Drug Combinations; Facial Pain; Female; Humans; Lactones; Logistic Models; Male; Molar, Third; Pain, Postoperative; Sulfones; Tooth Extraction

2005
A randomized, placebo-controlled study of rofecoxib with paracetamol in early post-tonsillectomy pain in adults.
    European journal of anaesthesiology, 2005, Volume: 22, Issue:10

    Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Humans; Lactones; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Preanesthetic Medication; Sulfones; Tonsillectomy

2005
Efficacy and safety of fast-track recovery strategy for patients undergoing laparoscopic nephrectomy.
    Journal of endourology, 2005, Volume: 19, Issue:10

    Topics: Acetaminophen; Adult; Aged; Analgesics; Antiemetics; Cyclooxygenase 2 Inhibitors; Female; Histamine H2 Antagonists; Humans; Kidney Neoplasms; Lactones; Laparoscopy; Length of Stay; Male; Middle Aged; Nephrectomy; Pain, Postoperative; Postoperative Care; Postoperative Nausea and Vomiting; Preoperative Care; Ranitidine; Sulfones

2005
Analgesic action of acetaminophen in symptomatic osteoarthritis of the knee.
    Rheumatology (Oxford, England), 2006, Volume: 45, Issue:6

    Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; beta-Endorphin; Biomarkers; Cyclooxygenase 2 Inhibitors; Female; Humans; Knee Joint; Lactones; Male; Middle Aged; Osteoarthritis, Knee; Pain Measurement; Serotonin; Severity of Illness Index; Substance P; Sulfones; Treatment Outcome

2006
Rofecoxib versus hydrocodone/acetaminophen for postoperative analgesia in functional endoscopic sinus surgery.
    The Laryngoscope, 2006, Volume: 116, Issue:4

    Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Endoscopy; Female; Follow-Up Studies; Humans; Hydrocodone; Lactones; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Paranasal Sinus Diseases; Prospective Studies; Sulfones; Treatment Outcome

2006
[Postoperative pain management in clinics of otolaryngology].
    Kulak burun bogaz ihtisas dergisi : KBB = Journal of ear, nose, and throat, 2006, Volume: 16, Issue:1

    Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Dipyrone; Etodolac; Female; Humans; Lactones; Male; Meloxicam; Middle Aged; Naproxen; Otorhinolaryngologic Surgical Procedures; Pain Measurement; Pain, Postoperative; Postoperative Period; Sulfones; Thiazines; Thiazoles; Treatment Outcome

2006
Combining paracetamol with a selective cyclooxygenase-2 inhibitor for acute pain relief after third molar surgery: a randomized, double-blind, placebo-controlled study.
    European journal of oral sciences, 2006, Volume: 114, Issue:4

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Cohort Studies; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Drug Combinations; Drug Synergism; Female; Follow-Up Studies; Humans; Ibuprofen; Lactones; Male; Middle Aged; Molar, Third; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Placebos; Sulfones; Tooth Extraction; Treatment Outcome

2006
Use of ketoprofen oral challenges to detect cross-reactors among patients with a history of aspirin-induced urticaria.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2006, Volume: 97, Issue:2

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross Reactions; Cyclooxygenase Inhibitors; Drug Hypersensitivity; Female; Humans; Ketoprofen; Lactones; Male; Middle Aged; Placebos; Sulfonamides; Sulfones; Tramadol; Urticaria

2006
Postoperative pain management after craniotomy: evaluation and cost analysis.
    Neurosurgery, 2006, Volume: 59, Issue:4

    Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Craniotomy; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Hospital Costs; Humans; Injections, Intravenous; Lactones; Length of Stay; Male; Middle Aged; Morphine; Narcotics; Oxycodone; Pain Measurement; Pain, Postoperative; Single-Blind Method; Sulfones; Treatment Outcome

2006
The efficacy of rofecoxib 50 mg and hydrocodone/acetaminophen 7.5/750 mg in patients with post-arthroscopic pain.
    Current medical research and opinion, 2007, Volume: 23, Issue:1

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Variance; Arthroscopy; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrocodone; Knee Joint; Lactones; Logistic Models; Male; Pain Measurement; Pain, Postoperative; Sulfones; Treatment Outcome

2007
A double-blind randomized controlled trial of rofecoxib and multidose oxycodone/acetaminophen in dental impaction pain.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2007, Volume: 65, Issue:8

    Topics: Acetaminophen; Adult; Analgesics; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Humans; Lactones; Male; Molar, Third; Oxycodone; Pain Measurement; Pain, Postoperative; Sulfones; Tooth Extraction; Tooth, Impacted

2007
Post-tonsillectomy pain management in children: can we do better?
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2007, Volume: 137, Issue:4

    Topics: Acetaminophen; Adolescent; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child, Preschool; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Drug Combinations; Elective Surgical Procedures; Follow-Up Studies; Humans; Hydrocodone; Lactones; Pain Measurement; Pain, Postoperative; Prospective Studies; Sulfones; Time Factors; Tonsillectomy; Treatment Outcome

2007
Comparative study of acetaminophen-morphine versus rofecoxib-morphine for post-tonsillectomy pain control.
    The Journal of otolaryngology, 2007, Volume: 36, Issue:5

    Topics: Acetaminophen; Adolescent; Analgesics, Opioid; Child; Child, Preschool; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Female; Humans; Lactones; Male; Morphine; Pain Measurement; Pain, Postoperative; Sulfones; Tonsillectomy

2007
The differential effects of bupivacaine and lidocaine on prostaglandin E2 release, cyclooxygenase gene expression and pain in a clinical pain model.
    Anesthesia and analgesia, 2008, Volume: 106, Issue:1

    Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Codeine; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Double-Blind Method; Enzyme Induction; Female; Humans; Lactones; Lidocaine; Male; Molar, Third; Mouth Mucosa; Oral Surgical Procedures; Pain Measurement; Pain, Postoperative; Sulfones; Time Factors; Tooth, Impacted

2008
A 4-week randomized study of acetaminophen extended-release vs rofecoxib in knee osteoarthritis.
    Osteoarthritis and cartilage, 2009, Volume: 17, Issue:1

    Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Cyclooxygenase 2 Inhibitors; Delayed-Action Preparations; Double-Blind Method; Drug Administration Schedule; Female; Humans; Lactones; Male; Middle Aged; Osteoarthritis, Knee; Pain Measurement; Severity of Illness Index; Sulfones; Treatment Outcome

2009

Other Studies

24 other study(ies) available for acetaminophen and rofecoxib

ArticleYear
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
[Cox-2 inhibitors in the focus. Rofecoxib as effective as the "classics"].
    MMW Fortschritte der Medizin, 2001, Nov-15, Volume: 143, Issue:46

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Celecoxib; Controlled Clinical Trials as Topic; Cyclooxygenase Inhibitors; Humans; Lactones; Morphine; Pain, Postoperative; Pyrazoles; Risk Factors; Spinal Fusion; Sulfonamides; Sulfones; Time Factors

2001
[Effective not only in rheumatism and arthrosis. Rofecoxib fights also acute pain].
    MMW Fortschritte der Medizin, 2002, Feb-14, Volume: 144, Issue:7

    Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Codeine; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Humans; Lactones; Middle Aged; Pain; Randomized Controlled Trials as Topic; Sulfones; Tooth Extraction

2002
Rofecoxib vs celecoxib vs acetaminophen for treatment of osteoarthritis.
    JAMA, 2002, Apr-10, Volume: 287, Issue:14

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; Humans; Lactones; Osteoarthritis; Pyrazoles; Sulfonamides; Sulfones

2002
Rofecoxib vs celecoxib vs acetaminophen for treatment of osteoarthritis.
    JAMA, 2002, Apr-10, Volume: 287, Issue:14

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; Humans; Lactones; Osteoarthritis; Pyrazoles; Sulfonamides; Sulfones

2002
Acute interstitial nephritis and COX-2 inhibition.
    Hospital medicine (London, England : 1998), 2003, Volume: 64, Issue:7

    Topics: Acetaminophen; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Humans; Isoenzymes; Lactones; Membrane Proteins; Nephritis, Interstitial; Prostaglandin-Endoperoxide Synthases; Sulfones

2003
Tolerability of cyclooxygenase 2 inhibitors and the advisability of oral challenge.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2003, Volume: 91, Issue:6

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Eruptions; Humans; Isoenzymes; Lactones; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Sulfones; Urticaria

2003
Results of a multimodal analgesic trial involving patients with total hip or total knee arthroplasty.
    American journal of orthopedics (Belle Mead, N.J.), 2004, Volume: 33, Issue:2

    Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bupivacaine; Dexamethasone; Female; Humans; Lactones; Length of Stay; Male; Middle Aged; Pain, Postoperative; Retrospective Studies; Sulfones; Tramadol

2004
Nonsteroidal anti-inflammatory drugs and acetaminophen in the treatment of an acute muscle injury.
    The American journal of sports medicine, 2004, Volume: 32, Issue:8

    Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Contusions; Drug Administration Schedule; Gait; Inflammation; Lactones; Male; Mice; Mice, Inbred C57BL; Models, Animal; Muscle Fibers, Skeletal; Muscle, Skeletal; Organ Size; Regeneration; Sulfones

2004
Cellular mechanisms of acetaminophen: role of cyclo-oxygenase.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2005, Volume: 19, Issue:6

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Cell Line; Cyclooxygenase Inhibitors; Diclofenac; Enzyme Activation; Humans; Ibuprofen; Indomethacin; Lactones; Lung; Naproxen; Oxidation-Reduction; Prostaglandin-Endoperoxide Synthases; Protein Biosynthesis; Sulfones; tert-Butylhydroperoxide; Transcription, Genetic

2005
The effect of analgesic agents on the healing rat medial collateral ligament.
    The American journal of sports medicine, 2005, Volume: 33, Issue:5

    Topics: Acetaminophen; Administration, Oral; Analgesics; Animals; Butorphanol; Collateral Ligaments; Disease Models, Animal; Dose-Response Relationship, Drug; Lactones; Naproxen; Piroxicam; Rats; Rats, Sprague-Dawley; Stress, Mechanical; Sulfones; Weight-Bearing; Wound Healing

2005
Treating pain after Vioxx. Should you switch to another COX-2, a traditional non-steroidal anti-inflammatory, or acetaminophen.
    Health news (Waltham, Mass.), 2005, Volume: 11, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Humans; Lactones; Pain; Sulfones

2005
Changes in dorsal root ganglion CGRP expression in a chronic inflammatory model of the rat knee joint: differential modulation by rofecoxib and paracetamol.
    European journal of pain (London, England), 2007, Volume: 11, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Arthritis, Experimental; Calcitonin Gene-Related Peptide; Cell Size; Chronic Disease; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Freund's Adjuvant; Ganglia, Spinal; Hyperalgesia; Immunohistochemistry; Lactones; Male; Neurons, Afferent; Osteoarthritis, Knee; Rats; Sulfones

2007
Trying times for painkiller choices. Vioxx, Bextra, and Celebrex can increase the risk for heart attack and other cardiovascular problems. So can the old standbys, like ibuprofen and acetaminophen.
    Harvard heart letter : from Harvard Medical School, 2006, Volume: 17, Issue:2

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Celecoxib; Cyclooxygenase Inhibitors; Gastrointestinal Diseases; Isoxazoles; Lactones; Pyrazoles; Risk Assessment; Sulfonamides; Sulfones

2006
Risks and benefits of COX-2 inhibitors vs non-selective NSAIDs: does their cardiovascular risk exceed their gastrointestinal benefit? A retrospective cohort study.
    Rheumatology (Oxford, England), 2007, Volume: 46, Issue:3

    Topics: Acetaminophen; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Cyclooxygenase 2 Inhibitors; Drug Prescriptions; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Hospitalization; Humans; Lactones; Male; Myocardial Infarction; Naproxen; Pyrazoles; Quebec; Retrospective Studies; Risk Assessment; Sulfonamides; Sulfones

2007
What happened to the prescribing of other COX-2 inhibitors, paracetamol and non-steroidal anti-inflammatory drugs when rofecoxib was withdrawn in Australia?
    Pharmacoepidemiology and drug safety, 2007, Volume: 16, Issue:11

    Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Australia; Cyclooxygenase 2 Inhibitors; Female; Humans; Lactones; Male; Middle Aged; Practice Patterns, Physicians'; Sulfones; Time Factors

2007
Perceived barriers to paracetamol (acetaminophen) prescribing, especially following rofecoxib withdrawal from the market.
    Clinical rheumatology, 2009, Volume: 28, Issue:5

    Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Cyclooxygenase 2 Inhibitors; Female; Focus Groups; Humans; Lactones; Male; Middle Aged; Osteoarthritis; Perception; Practice Patterns, Physicians'; Product Surveillance, Postmarketing; Sulfones

2009
Selective cyclooxygenase-2 (COX-2) inhibitors and breast cancer risk.
    Breast (Edinburgh, Scotland), 2011, Volume: 20, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Breast Neoplasms; Case-Control Studies; Celecoxib; Cyclooxygenase 2 Inhibitors; Databases, Factual; Female; Humans; Incidence; Isoxazoles; Lactones; Logistic Models; Middle Aged; Odds Ratio; Pyrazoles; Risk; Sulfonamides; Sulfones

2011
Clinical toxicology and drug regulation: a United Kingdom perspective.
    Clinical toxicology (Philadelphia, Pa.), 2011, Volume: 49, Issue:6

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Antipsychotic Agents; Antitussive Agents; Cyclooxygenase 2 Inhibitors; Dextropropoxyphene; Drug Combinations; Drug Overdose; Humans; Lactones; Legislation, Drug; Poison Control Centers; Product Recalls and Withdrawals; Sulfones; Toxicology; United Kingdom

2011