acetaminophen and quinone

acetaminophen has been researched along with quinone in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.26)18.7374
1990's2 (10.53)18.2507
2000's3 (15.79)29.6817
2010's11 (57.89)24.3611
2020's2 (10.53)2.80

Authors

AuthorsStudies
Baille, TA; Calleman, CJ; Pascoe, GA1
Fouad, FM; Mamer, OA; Shahidi, F1
Cederbaum, AI; Stoyanovsky, DA1
D'Ischia, M; Marotta, R; Napolitano, A; Vogna, D1
Becker, RS; Gartner, CA; Gygi, SP; Jones, G; Nelson, SD; Wan, J; Wen, B1
Bedner, M; MacCrehan, WA1
Alenmyr, L; Andersson, A; Andersson, DA; Bevan, S; Bucher, B; Galzi, JL; Gentry, C; Högestätt, ED; Killander, D; Lewis, SE; Sterner, O; Zygmunt, PM1
Banerjee, R; Chatterjee, IB; Chatterjee, NS; Choudhury, A; Chowdhury, R; Das, A; Das, T; Ghosh, A; Panda, K1
Badea, IA; Călinescu, O; Meltzer, V; Pincu, E; Vlădescu, L1
Gallard, H; Huguet, M; Simon, V1
Jørgensen, FS; Leth, R; Olsen, L; Rydberg, P1
Bois, F; Claude, I; Hamon, J; Jellali, R; Leclerc, E; Naudot, M1
Büter, L; Faber, H; Karst, U; Vogel, M; Wigger, T1
Ejiri, Y; Kotake, Y; Ohta, S; Sanoh, S; Santoh, M; Takagi, M1
Amadou Yacouba, Z; Avril, F; Bechelany, M; Bonniol, V; Cretin, M; Lacour, S; Le, TXH; Lesage, G; Mendret, J; Nguyen, DL; Nguyen, TV; Petit, E; Zoungrana, L1
de la Roche, J; Eberhardt, EM; Eberhardt, MJ; Echtermeyer, F; Herzog, C; Leffler, A; Risser, L; Schillers, F1
Blomgren, A; Grundemar, L; Högestätt, ED; Nilsson, JLÅ; Nilsson, UJ1
Ding, CH; Zhu, H1
Arnold, CG; D'Alessandro, A; Dart, R; Dylla, L; Heard, K; Heard, S; Monte, AA; Reynolds, K; Rumack, B; Sonn, B1

Other Studies

19 other study(ies) available for acetaminophen and quinone

ArticleYear
Identification of S-(2,5-dihydroxyphenyl)-cysteine and S-(2,5-dihydroxyphenyl)-N-acetyl-cysteine as urinary metabolites of acetaminophen in the mouse. Evidence for p-benzoquinone as a reactive intermediate in acetaminophen metabolism.
    Chemico-biological interactions, 1988, Volume: 68, Issue:1-2

    Topics: Acetaminophen; Acetylcysteine; Animals; Benzoquinones; Chromatography, High Pressure Liquid; Cysteine; Hydroquinones; Male; Mice; Mice, Inbred BALB C; Quinones

1988
Comparison of thermally oxidized lipids and acetaminophen with concurrent consumption of ethanol as inducers of liver cirrhosis.
    Journal of toxicology and environmental health, 1995, Volume: 46, Issue:2

    Topics: Acetaminophen; Acute-Phase Reaction; Analysis of Variance; Animals; Benzoquinones; DNA; Drug Interactions; Ethanol; Hepatectomy; Hot Temperature; Imines; Lipid Metabolism; Liver Cirrhosis, Experimental; Male; Necrosis; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms

1995
Metabolites of acetaminophen trigger Ca2+ release from liver microsomes.
    Toxicology letters, 1999, May-20, Volume: 106, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Benzoquinones; Ca(2+) Mg(2+)-ATPase; Calcium; Imines; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Ryanodine

1999
Advanced oxidation chemistry of paracetamol. UV/H(2)O(2)-induced hydroxylation/degradation pathways and (15)N-aided inventory of nitrogenous breakdown products.
    The Journal of organic chemistry, 2002, Aug-23, Volume: 67, Issue:17

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Benzoquinones; Chemistry, Organic; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Hydrogen Peroxide; Hydroxylation; Magnetic Resonance Spectroscopy; Molecular Structure; Nitrogen; Nitrogen Isotopes; Oxidation-Reduction; Stereoisomerism; Ultraviolet Rays

2002
Photochromic agents as tools for protein structure study: lapachenole is a photoaffinity ligand of cytochrome P450 3A4.
    Biochemistry, 2005, Feb-15, Volume: 44, Issue:6

    Topics: Acetaminophen; Aryl Hydrocarbon Hydroxylases; Benzopyrans; Benzoquinones; Binding Sites; Buffers; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Glutathione; Ligands; Midazolam; Nuclear Magnetic Resonance, Biomolecular; Oxidoreductases, N-Demethylating; Photoaffinity Labels; Photolysis; Recombinant Proteins; Ultraviolet Rays

2005
Transformation of acetaminophen by chlorination produces the toxicants 1,4-benzoquinone and N-acetyl-p-benzoquinone imine.
    Environmental science & technology, 2006, Jan-15, Volume: 40, Issue:2

    Topics: Acetaminophen; Benzoquinones; Biotransformation; Chlorine; Chromatography, Liquid; Imines; Mass Spectrometry; Spectrophotometry, Ultraviolet

2006
TRPA1 mediates spinal antinociception induced by acetaminophen and the cannabinoid Δ(9)-tetrahydrocannabiorcol.
    Nature communications, 2011, Nov-22, Volume: 2

    Topics: Acetaminophen; Acrolein; Analgesics; Animals; Benzoquinones; Calcium; Cannabinoids; Cell Line; CHO Cells; Cricetinae; Electrophysiology; Female; Humans; Imines; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Transient Receptor Potential Channels; TRPA1 Cation Channel

2011
Cigarette smoke induces p-benzoquinone-albumin adduct in blood serum: Implications on structure and ligand binding properties.
    Toxicology, 2012, Feb-26, Volume: 292, Issue:2-3

    Topics: Acetaminophen; Adult; Animals; Benzoquinones; Calorimetry, Differential Scanning; Circular Dichroism; Guinea Pigs; Humans; Lung; Male; Protein Binding; Protein Conformation; Quercetin; Serum Albumin; Smoking; Spectrometry, Fluorescence; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry, Ultraviolet

2012
HPLC separation of acetaminophen and its impurities using a mixed-mode reversed-phase/cation exchange stationary phase.
    Journal of chromatographic science, 2012, Volume: 50, Issue:4

    Topics: Acetaminophen; Acetanilides; Benzoquinones; Cations; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Chromatography, Reverse-Phase; Drug Contamination; Limit of Detection; Linear Models; Phenols; Reproducibility of Results; Tablets; Thermodynamics

2012
Transformation of paracetamol into 1,4-benzoquinone by a manganese oxide bed filter.
    Journal of hazardous materials, 2014, Apr-30, Volume: 271

    Topics: Acetaminophen; Benzoquinones; Catalysis; Filtration; Manganese Compounds; Oxides; Water Pollutants, Chemical; Water Purification

2014
Density functional theory study on the formation of reactive benzoquinone imines by hydrogen abstraction.
    Journal of chemical information and modeling, 2015, Mar-23, Volume: 55, Issue:3

    Topics: Acetaminophen; Benzoquinones; Cytochrome P-450 Enzyme System; Hydrogen; Imines; Models, Chemical; Oxidation-Reduction; Porphyrins

2015
Investigation of acetaminophen toxicity in HepG2/C3a microscale cultures using a system biology model of glutathione depletion.
    Cell biology and toxicology, 2015, Volume: 31, Issue:3

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Benzoquinones; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Glutathione; Hepatocytes; Humans; Liver; Models, Biological; Reactive Oxygen Species

2015
Differential protein labeling based on electrochemically generated reactive intermediates.
    Analytical chemistry, 2015, Oct-06, Volume: 87, Issue:19

    Topics: Acetaminophen; Animals; Benzoquinones; Carbonic Anhydrase I; Cattle; Chromatography, Liquid; Cysteine; Electrochemical Techniques; Equipment Design; Glutathione; Hemoglobins; Humans; Isotope Labeling; Lactoglobulins; Oxidation-Reduction; Phenol; Proteins; Serum Albumin; Spectrometry, Mass, Electrospray Ionization

2015
Acetaminophen induces accumulation of functional rat CYP3A via polyubiquitination dysfunction.
    Scientific reports, 2016, Feb-22, Volume: 6

    Topics: Acetaminophen; Animals; Benzoquinones; Cytochrome P-450 CYP3A; Gene Expression Regulation, Enzymologic; Glycoproteins; Humans; Inactivation, Metabolic; Polyubiquitin; Proteolysis; Rats; RNA, Messenger

2016
Correlation between degradation pathway and toxicity of acetaminophen and its by-products by using the electro-Fenton process in aqueous media.
    Chemosphere, 2017, Volume: 172

    Topics: Acetaminophen; Aliivibrio fischeri; Ammonium Compounds; Benzaldehydes; Benzoic Acid; Benzoquinones; Carbon; Carboxylic Acids; Catalysis; Electrochemical Techniques; Electrodes; Hydrogen Peroxide; Hydroxyl Radical; Iron; Kinetics; Nitrates; Oxidation-Reduction; Phenols; Water Pollutants, Chemical

2017
Reactive metabolites of acetaminophen activate and sensitize the capsaicin receptor TRPV1.
    Scientific reports, 2017, 10-06, Volume: 7, Issue:1

    Topics: Acetaminophen; Animals; Benzoquinones; Calcium; Capsaicin; Cell Death; Cysteine; Ganglia, Spinal; HEK293 Cells; Hepatocytes; Humans; Imines; Intracellular Space; Ion Channel Gating; Male; Metabolome; Mice, Inbred C57BL; Pain; Phosphorylation; Reducing Agents; Reflex; Regional Blood Flow; Skin; TRPV Cation Channels

2017
N,N'-Bis(2-mercaptoethyl)isophthalamide Binds Electrophilic Paracetamol Metabolites and Prevents Paracetamol-Induced Liver Toxicity.
    Basic & clinical pharmacology & toxicology, 2018, Volume: 123, Issue:5

    Topics: Acetaminophen; Acetylcysteine; Administration, Oral; Analgesics, Non-Narcotic; Animals; Antidotes; Benzene Derivatives; Benzoquinones; Chelating Agents; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Imines; Mice; Sulfhydryl Compounds

2018
Isatidis Folium alleviates acetaminophen-induced liver injury in mice by enhancing the endogenous antioxidant system.
    Environmental toxicology, 2020, Volume: 35, Issue:11

    Topics: Acetaminophen; Animals; Antioxidants; Benzoquinones; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Cytochrome P-450 CYP1A2; Glutathione; Imines; Liver; Male; Mice; Plant Extracts; Plant Leaves

2020
Metabolomic Evaluation of N-Acetyl-p-Benzoquinone Imine Protein Adduct Formation with Therapeutic Acetaminophen Administration: Sex-based Physiologic Differences.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2022, Volume: 18, Issue:4

    Topics: Acetaminophen; Adult; Alanine Transaminase; Analgesics, Non-Narcotic; Benzoquinones; Female; Glutathione; Humans; Imines; Lactates; Lipids; Male; Metabolome; Retrospective Studies; Sex Factors

2022