acetaminophen has been researched along with quercetin in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (2.94) | 18.2507 |
| 2000's | 7 (20.59) | 29.6817 |
| 2010's | 23 (67.65) | 24.3611 |
| 2020's | 3 (8.82) | 2.80 |
| Authors | Studies |
|---|---|
| Strassburg, CP; Tukey, RH | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Gilani, AH; Janbaz, KH; Shah, BH | 1 |
| Calixto, JB; Cechinel-Filho, V; Vaz, ZR; Yunes, RA; Zunino, L | 1 |
| De Santi, C; Marchetti, F; Mosca, F; Pacifici, GM; Pietrabissa, A; Spisni, R; Vietri, M | 1 |
| Boulkour, S; Fillastre, JP; Lahouel, M; Segueni, N | 1 |
| Gilani, AH; Janbaz, KH; Saeed, SA | 1 |
| Küpeli, E; Orhan, DD; Yesilada, E | 1 |
| Blumberg, JB; Bolling, BW; Chen, CY; Court, MH | 1 |
| Chaves, MM; Costa, DC; Humberto, JL; Pádua, Bda C; Pedrosa, ML; Rossoni Júnior, JV; Silva, LD; Silva, ME | 1 |
| Abdelmegid, LA; El-Guendi, MI; Omar, SA; Yousef, MI | 1 |
| Banerjee, R; Chatterjee, IB; Chatterjee, NS; Choudhury, A; Chowdhury, R; Das, A; Das, T; Ghosh, A; Panda, K | 1 |
| Finel, M; Häkli, M; Ketola, RA; Kidron, H; Manevski, N; Urtti, A; Wissel, G; Xhaard, H; Yliperttula, M | 1 |
| Ahmed, OA; Ahmed, TA; Badr, JM; Badr-Eldin, SM; El-Say, KM; Tawfik, MK | 1 |
| Challa, SR; Pawar, AK; Pingili, RB | 1 |
| Arakawa, NS; Cardoso, RD; Casagrande, R; Fattori, V; Hohmann, MS; Lopes, NP; Tomaz, JC; Verri, WA | 1 |
| Jiang, Z; Melzig, MF; Wang, J; Xie, W; Zhang, X | 1 |
| Jiang, Z; Wang, J; Wang, M; Xie, W; Xue, H; Zhang, X; Zhao, H | 1 |
| Chen, C; Melzig, MF; Wang, M; Xie, W; Zhang, X | 1 |
| Jeong, WS; Jun, M; Ko, SY; Truong, VL | 1 |
| Chandran, R; de Souza Araújo, AA; Júnior, LJQ; Lima, BDS; Narain, N; Serafini, MR; Shanmugam, S; Thangaraj, P | 1 |
| Antelava, N; Ghonghadze, M; Liluashvili, K; Okujava, M; Pachkoria, K | 1 |
| Aluani, D; Apostolov, A; Kondeva-Burdina, M; Odzhakov, F; Tzankova, V; Yoncheva, K; Yordanov, Y | 1 |
| Cao, L; Greenblatt, DJ; Kwara, A | 1 |
| Akhtar, MF; Ali, HA; Irshad, I; Saleem, A; Saleem, M; Saleem, U | 1 |
| Chen, W; Ding, T; Fan, J; Ju, D; Liu, H; Luan, J; Wu, Z; Zai, W; Zhang, X | 1 |
| Chen, L; Hu, C; Jia, Y; Li, X; Liu, X; Pan, L; Wang, Y; Ye, J; You, L; Zhang, J; Zhao, L | 1 |
| Barai, M; Tomassone, MS; Winkler, JS | 1 |
| Al Humayed, S; Al-Ani, B; Aziz, S; Eid, RA; El Karib, AO; Haidara, MA; Shatoor, AS; Wani, JI | 1 |
| Abdel Kader, DH; Al-Ani, B; Dallak, M; Dawood, AF; Eid, RA; Haidara, MA; Kamar, SS; Shams Eldeen, AM | 1 |
| Ebrahim, HY; El-Sayed, EK; Elsayed, HE; Khattab, MA; Mady, MS; Moharram, FA | 1 |
| Abdelgawad, MA; Abourehab, MAS; Ahmed, HY; Ahmed, OM; Eldin, DN; Fahim, HI | 1 |
1 review(s) available for acetaminophen and quercetin
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
33 other study(ies) available for acetaminophen and quercetin
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Quercetin exhibits hepatoprotective activity in rats.
Topics: Acetaminophen; Administration, Oral; Animals; Liver; Male; Mice; Quercetin; Rats; Rats, Wistar | 1997 |
Antinociceptive and anti-oedematogenic properties of astilbin, taxifolin and some related compounds.
Topics: Acetaminophen; Acetates; Analgesics; Analgesics, Non-Narcotic; Animals; Aspirin; Edema; Flavonoids; Flavonols; Formaldehyde; Ibuprofen; Indomethacin; Male; Mice; Pain Measurement; Quercetin; Rats; Rats, Wistar | 2000 |
Differential inhibition of human liver and duodenum sulphotransferase activities by quercetin, a flavonoid present in vegetables, fruit and wine.
Topics: Acetaminophen; Aged; Albuterol; Biological Availability; Dopamine; Drug Interactions; Duodenum; Female; Fruit; Humans; Inhibitory Concentration 50; Liver; Male; Middle Aged; Minoxidil; Quercetin; Sulfotransferases; Vegetables; Wine | 2001 |
[The flavonoids effect against vinblastine, cyclophosphamide and paracetamol toxicity by inhibition of lipid-peroxydation and increasing liver glutathione concentration].
Topics: Acetaminophen; Animals; Cyclophosphamide; Diosmin; Female; Flavonols; Glutathione; Hepatocytes; Kinetics; Lipid Peroxidation; Liver; Malondialdehyde; Models, Animal; Quercetin; Rats; Rats, Wistar; Time Factors; Vinblastine | 2004 |
Studies on the protective effects of caffeic acid and quercetin on chemical-induced hepatotoxicity in rodents.
Topics: Acetaminophen; Administration, Oral; Alanine Transaminase; Animals; Aspartate Aminotransferases; Caffeic Acids; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Male; Mice; Phytotherapy; Plants, Medicinal; Protective Agents; Quercetin; Rats | 2004 |
Effect of Cistus laurifolius L. leaf extracts and flavonoids on acetaminophen-induced hepatotoxicity in mice.
Topics: Acetaminophen; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cistus; Flavonoids; Flavonols; Glutathione; Kaempferols; Lipid Peroxidation; Liver; Liver Diseases; Male; Malondialdehyde; Mice; Plant Extracts; Plant Leaves; Quercetin; Turkey | 2006 |
The kinetic basis for age-associated changes in quercetin and genistein glucuronidation by rat liver microsomes.
Topics: Acetaminophen; Animals; Antioxidants; Flavonoids; Genistein; Glucuronic Acid; Kinetics; Male; Microsomes, Liver; Protein Isoforms; Protein Kinase Inhibitors; Quercetin; Rats; Rats, Inbred F344; Time Factors | 2010 |
Antioxidant properties of Baccharis trimera in the neutrophils of Fisher rats.
Topics: Acetaminophen; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Baccharis; Cells, Cultured; Dose-Response Relationship, Drug; Male; Neutrophils; Plant Components, Aerial; Plant Extracts; Quercetin; Rats; Rats, Inbred F344; Reactive Oxygen Species; Time Factors; Zymosan | 2010 |
Potential protective effects of quercetin and curcumin on paracetamol-induced histological changes, oxidative stress, impaired liver and kidney functions and haematotoxicity in rat.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Curcumin; Glutathione; Hematologic Diseases; Hematologic Tests; Kidney; Liver; Male; Necrosis; Oxidative Stress; Oxidoreductases; Quercetin; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances | 2010 |
Cigarette smoke induces p-benzoquinone-albumin adduct in blood serum: Implications on structure and ligand binding properties.
Topics: Acetaminophen; Adult; Animals; Benzoquinones; Calorimetry, Differential Scanning; Circular Dichroism; Guinea Pigs; Humans; Lung; Male; Protein Binding; Protein Conformation; Quercetin; Serum Albumin; Smoking; Spectrometry, Fluorescence; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry, Ultraviolet | 2012 |
Impact of probe compound in MRP2 vesicular transport assays.
Topics: Acetaminophen; Animals; Baculoviridae; Biological Assay; Biological Transport; Budesonide; Cell Membrane; Cells, Cultured; Diclofenac; Disopyramide; Estradiol; Estrone; Fluoresceins; Genetic Vectors; Humans; Indomethacin; Inhibitory Concentration 50; Leukotriene C4; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Quercetin; Recombinant Proteins; Spodoptera; Statistics as Topic; Thioridazine; Transfection | 2012 |
Design and optimization of self-nanoemulsifying delivery system to enhance quercetin hepatoprotective activity in paracetamol-induced hepatotoxicity.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Chemistry, Pharmaceutical; Drug Delivery Systems; Drug Design; Emulsions; Lipid Peroxidation; Liver Function Tests; Nanoparticles; Particle Size; Polyethylene Glycols; Polysorbates; Protective Agents; Quercetin; Rats; Silymarin; Solubility; Spectrophotometry, Ultraviolet; Surface-Active Agents | 2014 |
Systemic exposure of Paracetamol (acetaminophen) was enhanced by quercetin and chrysin co-administration in Wistar rats and in vitro model: risk of liver toxicity.
Topics: Acetaminophen; Administration, Oral; Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzoquinones; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2E1; Dose-Response Relationship, Drug; Drug Interactions; Flavonoids; Imines; Intestinal Absorption; Male; Quercetin; Rats; Rats, Wistar | 2015 |
Hypericum perforatum Reduces Paracetamol-Induced Hepatotoxicity and Lethality in Mice by Modulating Inflammation and Oxidative Stress.
Topics: Acetaminophen; Alanine Transaminase; Animals; Anthracenes; Anti-Inflammatory Agents; Antioxidants; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Glutathione; Hypericum; Inflammation; Male; Mice; Oxidative Stress; Perylene; Phloroglucinol; Plant Extracts; Plants, Medicinal; Quercetin; Rutin; Terpenes; Tumor Necrosis Factor-alpha | 2015 |
Protective effect of hyperoside against acetaminophen (APAP) induced liver injury through enhancement of APAP clearance.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Drug Overdose; Gene Expression Regulation, Enzymologic; Glucuronosyltransferase; Liver; Male; Mice; NF-E2-Related Factor 2; Oxidative Stress; Quercetin; RNA, Messenger; Sulfotransferases; Tyrosine | 2016 |
3,4-Dihydroxyphenylacetic acid, a microbiota-derived metabolite of quercetin, attenuates acetaminophen (APAP)-induced liver injury through activation of Nrf-2.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Mice; Microbiota; NF-E2-Related Factor 2; Oxidative Stress; Protective Agents; Quercetin | 2016 |
Hepatoprotective effect of isoquercitrin against acetaminophen-induced liver injury.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents; Biphenyl Compounds; Chemical and Drug Induced Liver Injury; Cytokines; Inflammation Mediators; Liver; Liver Function Tests; Male; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; Oxidative Stress; Picrates; Protective Agents; Quercetin; RNA, Messenger | 2016 |
Quercitrin from Toona sinensis (Juss.) M.Roem. Attenuates Acetaminophen-Induced Acute Liver Toxicity in HepG2 Cells and Mice through Induction of Antioxidant Machinery and Inhibition of Inflammation.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidant Response Elements; Antioxidants; Chemical and Drug Induced Liver Injury; Dietary Supplements; Ethnopharmacology; Hep G2 Cells; Humans; Liver; Male; MAP Kinase Signaling System; Medicine, East Asian Traditional; Meliaceae; Mice, Inbred BALB C; Necrosis; Oxidative Stress; Plant Leaves; Quercetin; Random Allocation | 2016 |
Effects of luteolin and quercetin 3-β-d-glucoside identified from Passiflora subpeltata leaves against acetaminophen induced hepatotoxicity in rats.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Luteolin; Male; Mice; Passiflora; Plant Extracts; Plant Leaves; Quercetin; Rats; Rats, Wistar; Treatment Outcome | 2016 |
[EFFECT OF ACETYLCYSTEINE, CORVITIN AND THEIR COMBINATION ON THE FUNCTIONAL STATE OF LIVER IN RATS WITH PARACETAMOL INDUCED TOXIC HEPATITIS].
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Flavonoids; Liver; Male; Protective Agents; Rats, Wistar | 2017 |
Hepatoprotective and antioxidant activity of quercetin loaded chitosan/alginate particles in vitro and in vivo in a model of paracetamol-induced toxicity.
Topics: Acetaminophen; Alginates; Animals; Antioxidants; Cell Survival; Chemical and Drug Induced Liver Injury; Chitosan; Dose-Response Relationship, Drug; Drug Carriers; Glucuronic Acid; Hep G2 Cells; Hexuronic Acids; Humans; Male; Quercetin; Rats; Rats, Wistar | 2017 |
Metabolic interactions between acetaminophen (paracetamol) and two flavonoids, luteolin and quercetin, through in-vitro inhibition studies.
Topics: Acetaminophen; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Humans; Inhibitory Concentration 50; Luteolin; Microsomes, Liver; Quercetin | 2017 |
Chemical characterisation and hepatoprotective potential of Cosmos sulphureus Cav. and Cosmos bipinnatus Cav.
Topics: Acetaminophen; Animals; Antioxidants; Asteraceae; Chemical and Drug Induced Liver Injury; Hepatocytes; Liver; Pakistan; Phenols; Plant Extracts; Quercetin; Rats; Rats, Wistar; Silymarin | 2019 |
Dihydroquercetin ameliorated acetaminophen-induced hepatic cytotoxicity via activating JAK2/STAT3 pathway and autophagy.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Autophagy; Cells, Cultured; Hepatocytes; Janus Kinase 2; Liver; Mice; Mice, Inbred C57BL; Quercetin; Signal Transduction; STAT3 Transcription Factor | 2018 |
5,7,3',4'-flavan-on-ol (taxifolin) protects against acetaminophen-induced liver injury by regulating the glutathione pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Glutathione; Metabolome; Mice; Mice, Inbred C57BL; Oxidative Stress; Protective Agents; Quercetin; Reactive Oxygen Species | 2019 |
Dual drug-loaded biodegradable Janus particles for simultaneous co-delivery of hydrophobic and hydrophilic compounds.
Topics: Acetaminophen; Biocompatible Materials; Curcumin; Diffusion; Drug Delivery Systems; Drug Liberation; Emulsions; Hydrophobic and Hydrophilic Interactions; Naproxen; Oils; Particle Size; Pharmaceutical Preparations; Polyesters; Polylactic Acid-Polyglycolic Acid Copolymer; Quercetin; Solvents; Spectrophotometry, Ultraviolet; Water | 2019 |
Suppression of acetaminophen-induced hepatocyte ultrastructural alterations in rats using a combination of resveratrol and quercetin.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Hepatocytes; Microscopy, Electron, Transmission; Quercetin; Rats; Rats, Sprague-Dawley; Resveratrol | 2019 |
Suppression of glomerular damage and apoptosis and biomarkers of acute kidney injury induced by acetaminophen toxicity using a combination of resveratrol and quercetin.
Topics: Acetaminophen; Acute Kidney Injury; Animals; Apoptosis; Biomarkers; Chemical and Drug Induced Liver Injury; Endothelial Cells; Liver; Oxidative Stress; Quercetin; Rats; Resveratrol | 2022 |
Ethnopharmacological impact of Melaleuca rugulosa (Link) Craven leaves extract on liver inflammation.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Antioxidants; Chemical and Drug Induced Liver Injury; Flavonoids; Inflammation; Liver; Melaleuca; Methanol; Methyl Ethers; NF-kappa B; Plant Extracts; Plant Leaves; Quercetin; Rats; Tumor Necrosis Factor-alpha | 2022 |
Preventive Effects of Mandarin Fruit Peel Hydroethanolic Extract, Hesperidin, and Quercetin on Acetaminophen-Induced Hepatonephrotoxicity in Wistar Rats.
Topics: Acetaminophen; Animals; Fruit; Glutathione Transferase; Hesperidin; Male; Oxidative Stress; Quercetin; Rats; Rats, Wistar | 2022 |