acetaminophen and propylthiouracil

acetaminophen has been researched along with propylthiouracil in 31 studies

Research

Studies (31)

Timeframe	Studies, this research(%)	All Research%
pre-1990	8 (25.81)	18.7374
1990's	2 (6.45)	18.2507
2000's	10 (32.26)	29.6817
2010's	11 (35.48)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Avdeef, A; Tam, KY	1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Davis, M	1
Cho, CD; Hirose, N; Raheja, KL	1
Hodkinson, BA; Laleli, YR; McIntyre, PA; Wagner, HN	1
Cho, C; Linscheer, WG; Raheja, KL	1
Cho, CD; Landaw, SA; Linscheer, WG; Raheja, KL	1
Cho, C; Linscheer, WG; Mahany, D; Raheja, KL	1
Kaplowitz, N; Kuhlenkamp, J; Ludwig, S; Yamada, T	1
Cho, C; Linscheer, WG; Raheja, KL; Smith, NJ	1
Heathcote, J; Wanless, IR	1
Banerjee, A; Chan, SH; Chiji, H; Cho, C; Linscheer, WG; Murthy, UK; Nandi, J	1
Abraham, P; Dian, BJ; Kanakasabapathy, I	1
Chaiyakunapruk, N; Jampachaisri, K; Kotirum, S; Rojnuckarin, P; Wattanasombat, S	1
Ajala, AM; Goodwin, JA; Goodwin, SR; Josephson, GD	1
Kuehn, BM	1
Lewis, JH; Stine, JG	1
Jones, KL; Kiernan, E	1

Reviews

5 review(s) available for acetaminophen and propylthiouracil

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Protective agents for acetaminophen overdose. Seminars in liver disease, 1986, Volume: 6, Issue:2 Topics: Acetaminophen; Acetylcysteine; Animals; Cell Membrane; Chemical and Drug Induced Liver Injury; Cimetidine; Cysteamine; Glucuronates; Glutathione; Humans; Inactivation, Metabolic; Lipid Peroxides; Liver; Methionine; Necrosis; Propylthiouracil	1986
Hepatotoxicity: newer aspects of pathogenesis and treatment. The Gastroenterologist, 1995, Volume: 3, Issue:2 Topics: Acetaminophen; Acetylcysteine; Adenoma, Liver Cell; Adult; Amoxicillin; Anabolic Agents; Beverages; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Contraceptives, Oral; Female; Humans; Isoniazid; Liver Diseases; Liver Diseases, Alcoholic; Liver Neoplasms; Male; Nonprescription Drugs; Propylthiouracil; Rifampin	1995
Drug-induced liver injury: a summary of recent advances. Expert opinion on drug metabolism & toxicology, 2011, Volume: 7, Issue:7 Topics: Acetaminophen; Antiretroviral Therapy, Highly Active; Antitubercular Agents; Biomarkers; Catha; Chemical and Drug Induced Liver Injury; Cimicifuga; Humans; Hypoglycemic Agents; Kava; Liver; Plant Preparations; Propylthiouracil; Randomized Controlled Trials as Topic; Risk Factors	2011
Medications that Cause Fetal Anomalies and Possible Prevention Strategies. Clinics in perinatology, 2019, Volume: 46, Issue:2 Topics: Abnormalities, Drug-Induced; Acetaminophen; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Analgesics, Non-Narcotic; Anti-Asthmatic Agents; Antidepressive Agents; Antiemetics; Antithyroid Agents; Asthma; Congenital Abnormalities; Depressive Disorder; Female; Humans; Hyperthyroidism; Leukotriene Antagonists; Maternal-Fetal Exchange; Methimazole; Morning Sickness; Ondansetron; Pregnancy; Pregnancy Complications; Propylthiouracil; Teratogens	2019

Other Studies

26 other study(ies) available for acetaminophen and propylthiouracil

Article	Year
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability? Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9 Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis	2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR. European journal of medicinal chemistry, 2011, Volume: 46, Issue:1 Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Effect of nutritional status on propylthiouracil-induced protection against acetaminophen hepatotoxicity in the rat. Drug-nutrient interactions, 1987, Volume: 5, Issue:1 Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Food; Food Deprivation; Liver Diseases; Male; Propylthiouracil; Rats; Rats, Inbred Strains	1987
Evidence for anti-leukocyte antibodies as a mechanism for drug-induced agranulocytosis. Transactions of the Association of American Physicians, 1971, Volume: 84 Topics: Acetaminophen; Adult; Aged; Agranulocytosis; Animals; Blood Transfusion; Carbon Dioxide; Carbon Radioisotopes; Felty Syndrome; Female; Glucose; Humans; Immunoglobulin G; In Vitro Techniques; Isoantibodies; Leukocytes; Methyldopa; Polystyrenes; Prednisone; Primidone; Propylthiouracil; Rabbits	1971
Prevention of acetaminophen hepatotoxicity by propylthiouracil in the glutathione depleted rat. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1983, Volume: 76, Issue:1 Topics: Acetaminophen; Animals; Free Radicals; Glutathione; Hypothyroidism; Liver; Male; Maleates; Propylthiouracil; Rats	1983
Effect of acetaminophen toxicity on erythrocyte osmotic fragility in the Fisher rat. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1984, Volume: 79, Issue:1 Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Glutathione; Hepatitis, Animal; Liver; Liver Glycogen; Male; Organ Size; Osmotic Fragility; Propylthiouracil; Rats	1984
Protective effect of propylthiouracil independent of its hypothyroid effect on acetaminophen toxicity in the rat. The Journal of pharmacology and experimental therapeutics, 1982, Volume: 220, Issue:2 Topics: Acetaminophen; Animals; Glutathione; Hyperthyroidism; Hypothyroidism; Liver; Liver Glycogen; Male; Propylthiouracil; Rats; Rats, Inbred Strains; Transaminases; Triiodothyronine	1982
Direct protection against acetaminophen hepatotoxicity by propylthiouracil. In vivo and in vitro studies in rats and mice. The Journal of clinical investigation, 1981, Volume: 67, Issue:3 Topics: Acetaminophen; Animals; Bile; Glutathione; Glutathione Transferase; Liver; Mice; Microsomes, Liver; Propylthiouracil; Rats	1981
Mechanism of the protective effect of propylthiouracil against acetaminophen (Tylenol) toxicity in the rat. Gastroenterology, 1980, Volume: 78, Issue:1 Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Glutathione; Hypothyroidism; Liver; Male; Necrosis; Propylthiouracil; Rats; Thyroid Gland; Thyroidectomy	1980
Induction of an ATPase inhibitor protein by propylthiouracil and protection against paracetamol (acetaminophen) hepatotoxicity in the rat. British journal of pharmacology, 1998, Volume: 124, Issue:6 Topics: Acetaminophen; Adenosine Triphosphatases; Adenosine Triphosphate; Alanine Transaminase; Animals; Aspartate Aminotransferases; ATPase Inhibitory Protein; Enzyme Inhibitors; Glutathione; Liver; Male; Propylthiouracil; Protein Biosynthesis; Proteins; Rats; Rats, Wistar	1998
Propylthiouracil attenuates acetaminophen-induced renal damage in the rat. Nephrology (Carlton, Vic.), 2005, Volume: 10, Issue:6 Topics: Acetaminophen; Animals; Creatinine; Dose-Response Relationship, Drug; Kidney; Kidney Diseases; Lipid Peroxides; Male; Propylthiouracil; Rats; Rats, Wistar; Sulfhydryl Compounds; Urea	2005
Utilization review of concomitant use of potentially interacting drugs in Thai patients using warfarin therapy. Pharmacoepidemiology and drug safety, 2007, Volume: 16, Issue:2 Topics: Acetaminophen; Adult; Ambulatory Care; Analgesics, Non-Narcotic; Anticoagulants; Antithyroid Agents; Aspirin; Diclofenac; Drug Interactions; Drug Monitoring; Drug Prescriptions; Drug Utilization Review; Female; Follow-Up Studies; Humans; International Normalized Ratio; Male; Middle Aged; Polypharmacy; Propylthiouracil; Retrospective Studies; Thailand; Warfarin	2007
Undiagnosed Graves' Disease contributing to sleep disordered breathing in a child undergoing adenotonsillectomy. Paediatric anaesthesia, 2008, Volume: 18, Issue:4 Topics: Acetaminophen; Adenoidectomy; Adenoids; Analgesics, Non-Narcotic; Analgesics, Opioid; Antihypertensive Agents; Antithyroid Agents; Atenolol; Child; Fentanyl; Follow-Up Studies; Graves Disease; Humans; Hydrocodone; Hypertension; Male; Palatine Tonsil; Propylthiouracil; Sleep Apnea Syndromes; Tachycardia; Thyroid Gland; Tonsillectomy	2008
FDA focuses on drugs and liver damage: labeling and other changes for acetaminophen. JAMA, 2009, Jul-22, Volume: 302, Issue:4 Topics: Acetaminophen; Analgesics, Non-Narcotic; Antithyroid Agents; Chemical and Drug Induced Liver Injury; Drug Labeling; Genome-Wide Association Study; Humans; Major Histocompatibility Complex; Propylthiouracil; United States; United States Food and Drug Administration	2009