acetaminophen has been researched along with piperine in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 3 (37.50) | 2.80 |
| Authors | Studies |
|---|---|
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Bharate, SS; Vishwakarma, RA | 1 |
| Borges, F; Chavarria, D; Fernandes, C; Gil-Martins, E; Oliveira, PJ; Remião, F; Silva, C; Silva, R; Silva, T; Silva, V; Soares, P | 1 |
| Cashman, JR; Court, MH; Ghirmai, S; Volak, LP | 1 |
| Fong, YK; Li, CR; Lin, G; Wang, S; Wo, SK; Zhang, L; Zhou, L; Zuo, Z | 1 |
| Badmaev, V; Court, MH; Greenblatt, DJ; Hanley, MJ; Harmatz, JS; Hazarika, S; Majeed, M; Masse, G; Volak, LP | 1 |
| Al Turaifi, FH; El-Daly, M; El-Sheikh, AAK; Mohafez, OM; Morsy, MA; Younis, NS | 1 |
| Afroze, M; Al-Khafaji, K; Araújo, IM; Asha, UH; Coutinho, HDM; de Lacerda, BCGV; El-Kersh, DM; Islam, MT; Jamaddar, S; Khalipha, ABR; Khan, M; Mondal, M; Moniruzzaman, M; Mori, E; Ray, P; Roy, UK; Sarkar, C; Shill, MC | 1 |
1 trial(s) available for acetaminophen and piperine
| Article | Year |
|---|---|
Effect of a herbal extract containing curcumin and piperine on midazolam, flurbiprofen and paracetamol (acetaminophen) pharmacokinetics in healthy volunteers.
Topics: Acetaminophen; Alkaloids; Analgesics, Non-Narcotic; Area Under Curve; Benzodioxoles; Chromatography, High Pressure Liquid; Cross-Over Studies; Curcuma; Curcumin; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Double-Blind Method; Drug Interactions; Enzyme Inhibitors; Flurbiprofen; Half-Life; Humans; Hypnotics and Sedatives; Midazolam; Piperidines; Plant Extracts; Polyunsaturated Alkamides | 2013 |
7 other study(ies) available for acetaminophen and piperine
| Article | Year |
|---|---|
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery.
Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics | 2015 |
Design of novel monoamine oxidase-B inhibitors based on piperine scaffold: Structure-activity-toxicity, drug-likeness and efflux transport studies.
Topics: Alkaloids; Benzodioxoles; Caco-2 Cells; Cell Differentiation; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Humans; Ligands; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Oxidative Stress; Piperidines; Polyunsaturated Alkamides; Structure-Activity Relationship; Tumor Cells, Cultured | 2020 |
Curcuminoids inhibit multiple human cytochromes P450, UDP-glucuronosyltransferase, and sulfotransferase enzymes, whereas piperine is a relatively selective CYP3A4 inhibitor.
Topics: Acetaminophen; Alkaloids; Benzodioxoles; Chromatography, High Pressure Liquid; Curcumin; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Glucuronosyltransferase; Humans; Liver; Piperidines; Polyunsaturated Alkamides; Recombinant Proteins; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Sulfotransferases | 2008 |
In vitro and in situ evaluation of herb-drug interactions during intestinal metabolism and absorption of baicalein.
Topics: Acetaminophen; Administration, Oral; Alkaloids; Animals; Benzodioxoles; Biotransformation; Caco-2 Cells; Catechin; Chromatography, Liquid; Curcumin; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Flavanones; Glucuronides; Herb-Drug Interactions; Humans; Intestinal Absorption; Jejunum; Male; Medicine, Chinese Traditional; Perfusion; Piperidines; Plant Roots; Plants, Medicinal; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Scutellaria baicalensis; Sulfates; Tandem Mass Spectrometry | 2012 |
Protective mechanisms of piperine against acetaminophen-induced hepatotoxicity may be mediated through TGFBRAP1.
Topics: Acetaminophen; Alkaloids; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Benzodioxoles; Caspase 3; Chemical and Drug Induced Liver Injury; HSP90 Heat-Shock Proteins; Liver; Male; Mice; NF-E2-Related Factor 2; Oxidative Stress; Piperidines; Polyunsaturated Alkamides; Transcription Factor RelA | 2020 |
GC-MS analysis, and evaluation of protective effect of Piper chaba stem bark against paracetamol-induced liver damage in Sprague-Dawley rats: Possible defensive mechanism by targeting CYP2E1 enzyme through in silico study.
Topics: Acetaminophen; Alkaloids; Animals; Bilirubin; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Esters; Fatty Acids; Gas Chromatography-Mass Spectrometry; Lipids; Liver; Methanol; Piper; Plant Bark; Plant Extracts; Rats; Rats, Sprague-Dawley; Serum Albumin; Silymarin | 2022 |