acetaminophen and papaverine

acetaminophen has been researched along with papaverine in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19906 (28.57)18.7374
1990's1 (4.76)18.2507
2000's5 (23.81)29.6817
2010's8 (38.10)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Chłoń-Rzepa, G; Dąbrowska, M; Jankowska, A; Komsta, Ł; Pawłowski, M; Ślusarczyk, M; Starek, M; Zagórska, A1
Kaźmierczyk, J1
Beyrich, T; Schleuder, M1
Sharley, CB1
Maier-Lenz, H; Ringwelski, L; Windorfer, A1
Acosta, D; Anuforo, DC; Smith, RV1
Kaa, E1
KRISCHEK, J1
Charlier, C; Denooz, R; Dubois, N1
Abdellatef, HE; Ayad, MM; Soliman, SM; Youssef, NF1
Hegazy, MA; Lotfy, HM; Mohamed, EH; Mowaka, S1
Koli, J; Narang, S1

Reviews

2 review(s) available for acetaminophen and papaverine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Pharmacokinetics of interaction of N-acetyl-P-aminophenol with the drugs affecting the secretory and motor activity of the alimentary tract].
    Annales Academiae Medicae Stetinensis, 1979, Volume: 25

    Topics: Acetaminophen; Atropine; Biotransformation; Calcium Carbonate; Drug Interactions; Ethanol; Gastric Mucosa; Gastrointestinal Motility; Humans; Hydrochloric Acid; Kinetics; Male; Neostigmine; Papaverine; Pituitary Gland, Posterior; Tissue Extracts

1979

Trials

1 trial(s) available for acetaminophen and papaverine

ArticleYear
Efficacy and safety of fixed-dose combination of drotaverine hydrochloride (80 mg) and paracetamol (500 mg) in amelioration of abdominal pain in acute infectious gastroenteritis: A randomized controlled trial.
    Journal of gastroenterology and hepatology, 2018, Volume: 33, Issue:12

    Topics: Abdominal Pain; Acetaminophen; Acute Pain; Administration, Oral; Adolescent; Adult; Analgesics; Double-Blind Method; Drug Combinations; Dysentery; Female; Humans; India; Male; Middle Aged; Pain Measurement; Papaverine; Tablets; Time Factors; Treatment Outcome; Young Adult

2018

Other Studies

18 other study(ies) available for acetaminophen and papaverine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Estimation of the lipophilicity of purine-2,6-dione-based TRPA1 antagonists and PDE4/7 inhibitors with analgesic activity.
    Bioorganic & medicinal chemistry letters, 2021, 10-01, Volume: 49

    Topics: Analgesics; Benzeneacetamides; Cyclic Nucleotide Phosphodiesterases, Type 7; Hydrophobic and Hydrophilic Interactions; Molecular Structure; Phenylbutyrates; Phosphodiesterase 4 Inhibitors; Principal Component Analysis; Quantitative Structure-Activity Relationship; TRPA1 Cation Channel; Xanthines

2021
[Comparative study on quantitative determination of mixtures of analgesics. 1. Studies on selectivity of volumetric analysis procedures].
    Die Pharmazie, 1974, Volume: 29, Issue:7

    Topics: Acetaminophen; Aminopyrine; Analgesics; Ascorbic Acid; Aspirin; Barbiturates; Caffeine; Chlorpromazine; Codeine; Conductometry; Electrochemistry; Meprobamate; Mesylates; Methods; Papaverine; Phenacetin; Phenobarbital; Phenylbutazone; Potentiometry; Quinine; Salicylamides; Salicylates; Theobromine

1974
The value of physiotherapy in obstetrics.
    The Medical journal of Australia, 1970, Jun-06, Volume: 1, Issue:23

    Topics: Acetaminophen; Anesthesia, Obstetrical; Anesthetics, Local; Aspirin; Codeine; Conditioning, Psychological; Exercise Therapy; Female; Glutethimide; Humans; Infant, Newborn; Labor, Obstetric; Meperidine; Morphine; Natural Childbirth; Nitrous Oxide; Obstetric Labor Complications; Papaverine; Paraldehyde; Pentobarbital; Perineum; Phenobarbital; Physical Examination; Pregnancy; Promazine; Psychophysiology; Psychotherapy; Relaxation; Statistics as Topic

1970
[A comparative pharmacokinetic study for tablet and suppository formulations of a combination product of caffeine, ethaverine, propyphenazone, paracetamol and phenobarbital (author's transl)].
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:1

    Topics: Acetaminophen; Adult; Analgesics; Antipyrine; Caffeine; Drug Combinations; Humans; Kinetics; Male; Papaverine; Phenobarbital; Rectum; Suppositories; Tablets

1981
Cytotoxicity of acetaminophen and papaverine in primary cultures of rat hepatocytes.
    Toxicology and applied pharmacology, 1980, Volume: 53, Issue:2

    Topics: Acetaminophen; Animals; Cell Survival; Cells, Cultured; Liver; Nitrofurantoin; Papaverine; Rats; Salicylates; Time Factors

1980
Impurities, adulterants and diluents of illicit heroin. Changes during a 12-year period.
    Forensic science international, 1994, Volume: 64, Issue:2-3

    Topics: Acetaminophen; Caffeine; Carbohydrates; Denmark; Drug Contamination; Heroin; Hydrogen-Ion Concentration; Illicit Drugs; Lactose; Morphine; Noscapine; Papaverine; Phenobarbital; Procaine

1994
[Migraine therapy with migraine kranit].
    Die Medizinische Welt, 1951, Sep-15, Volume: 20, Issue:37

    Topics: Acetaminophen; Antipyrine; Caffeine; Drug Combinations; Humans; Migraine Disorders; Muscle Relaxants, Central; Papaverine; Phenobarbital

1951
[Analysis of two year heroin seizures in the Liege area].
    Revue medicale de Liege, 2005, Volume: 60, Issue:9

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Caffeine; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; France; Heroin; Law Enforcement; Noscapine; Papaverine

2005
Spectrophotometric and spectrodensitometric determination of paracetamol and drotaverine HCl in combination.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2007, Volume: 66, Issue:4-5

    Topics: Acetaminophen; Chromatography, Thin Layer; Densitometry; Hydrochloric Acid; Papaverine; Reproducibility of Results; Spectrophotometry, Ultraviolet

2007
Evaluation of the efficiency of continuous wavelet transform as processing and preprocessing algorithm for resolution of overlapped signals in univariate and multivariate regression analyses; an application to ternary and quaternary mixtures.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2016, 07-05, Volume: 164

    Topics: Acetaminophen; Algorithms; Aminophenols; Analgesics; Caffeine; Central Nervous System Stimulants; Least-Squares Analysis; Multivariate Analysis; Papaverine; Spectrophotometry; Wavelet Analysis

2016