acetaminophen has been researched along with orphenadrine in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (51.61) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (6.45) | 29.6817 |
| 2010's | 6 (19.35) | 24.3611 |
| 2020's | 7 (22.58) | 2.80 |
| Authors | Studies |
|---|---|
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Rebhun, J | 1 |
| Lepisto, P; Petaja, L; Tervo, T | 1 |
| Post, A; Winter, L | 1 |
| Valtonen, EJ | 1 |
| Gundersen, R; Høivik, HO; Osmundsen, K | 1 |
| Berge, OG; Hole, K; Hunskaar, S | 1 |
| Hingorani, K | 1 |
| Buchs, P | 1 |
| Gerstenbrand, F; Mamoli, B; Tilscher, H | 1 |
| Cliff, JM | 1 |
| Cohen, L | 1 |
| McGuinness, BW | 1 |
| Høivik, HO; Moe, N; Osmundsen, K | 1 |
| Høivik, HO; Moe, N | 1 |
| Friedman, GD | 1 |
| SLOANE, HS | 1 |
| Ruangwises, N; Sratthaphut, L | 1 |
| Abd El-Rahman, MK; Yehia, AM | 1 |
| Cunha, RR; Muñoz, RAA; Ribeiro, MMAC; Richter, EM | 1 |
| Boltia, SA; Elzanfaly, ES; Soudi, AT; Zaazaa, HE | 2 |
| El-Adl, SM; Mattar, AA; Sebaiy, MM | 1 |
| Cheah, KY; Mah, KY; Ng, SM; Pang, LH; Tan, HZ; Tan, SS; Wong, JW; Yuen, KH | 1 |
| Hassanzadeh, H; Mischak, I; Payer, M; Sandner-Kiesling, A; Schanbacher, M; Sendlhofer, G; Tomic, J; Wallner, J; Zemann, W; Zrnc, TA | 1 |
| Correia, AT; de Oliveira, TMN; Guimarães, LL; Pisetta, AM; Roveri, V | 1 |
| Correia, AT; Guimarães, LL; Roveri, V; Toma, W | 1 |
2 review(s) available for acetaminophen and orphenadrine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Non-narcotic analgesics--their use and abuse.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents; Aspirin; Dextropropoxyphene; Drug Synergism; Flufenamic Acid; Humans; Indomethacin; Mefenamic Acid; Methotrimeprazine; Orphenadrine; Oxyphenbutazone; Pentazocine; Phenacetin; Phenylbutazone; Propionates; Tablets | 1972 |
10 trial(s) available for acetaminophen and orphenadrine
| Article | Year |
|---|---|
A controlled clinical trial of a muscle relaxant analgesic combination in the treatment of acute lumbago.
Topics: Acetaminophen; Acute Disease; Adult; Back Pain; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Orphenadrine | 1976 |
Analgesic combinations with orphenadrine in oral post-surgical pain.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Clinical Trials as Topic; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Orphenadrine; Pain, Postoperative; Placebos; Surgery, Oral | 1979 |
A controlled clinical trial of chlormezanone, orphenadrine, orphenadrine/paracetamol and placebo in the treatment of painful skeletal muscle spasms.
Topics: Acetaminophen; Chlormezanone; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Humans; Muscle Cramp; Orphenadrine; Placebos | 1975 |
[Combined analgesics in myalgia of the neck. A double-blind comparison of paracetamol and orphenadrine (Norgesic) and paracetamol and codeine (Paralgin forte) in general practice].
Topics: Acetaminophen; Adolescent; Adult; Aged; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Muscles; Neck Muscles; Orphenadrine; Pain | 1986 |
Orphenadrin-paracetamol in backache-a double-blind controlled trial.
Topics: Acetaminophen; Adult; Aged; Aspirin; Back Pain; Clinical Trials as Topic; Drug Synergism; Female; Humans; Male; Middle Aged; Orphenadrine | 1971 |
A double-blind comparison in general practice of a combination tablet containing orphenadrine citrate and paracetamol ('Norgesic') with paracetamol alone.
Topics: Acetaminophen; Adolescent; Adult; Aged; Back Pain; Bone Diseases; Double-Blind Method; Drug Combinations; Drug Evaluation; Female; Humans; Male; Middle Aged; Muscle Spasticity; Muscular Diseases; Orphenadrine; Pain | 1983 |
[Effect of orphenadrine/paracetamol combination tablets (Norgesic) on myalgia. A double-blind comparative study using a placebo in general practice].
Topics: Acetaminophen; Adult; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Muscle Relaxants, Central; Neck; Orphenadrine; Pain; Placebos | 1983 |
Effect of a combination of orphenadrine/paracetamol tablets ('Norgesic') on myalgia: a double-blind comparison with placebo in general practice.
Topics: Acetaminophen; Adolescent; Adult; Aged; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Muscular Diseases; Orphenadrine; Pain | 1983 |
A randomized single-dose, two-period crossover bioequivalence study of two fixed-dose Paracetamol/Orphenadrine combination preparations in healthy volunteers under fasted condition.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Cross-Over Studies; Drug Combinations; Fasting; Healthy Volunteers; Humans; Male; Muscle Relaxants, Central; Orphenadrine; Therapeutic Equivalency; Young Adult | 2020 |
Intravenous ibuprofen versus diclofenac plus orphenadrine in orthognathic surgery: a prospective, randomized, double-blind, controlled clinical study.
Topics: Acetaminophen; Adolescent; Adult; Diclofenac; Double-Blind Method; Humans; Ibuprofen; Middle Aged; Orphenadrine; Orthognathic Surgery; Pain, Postoperative; Pirinitramide; Prospective Studies; Young Adult | 2022 |
19 other study(ies) available for acetaminophen and orphenadrine
| Article | Year |
|---|---|
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A unique pigment disorder in an atopic patient with hyperimmunoglobulinemia E.
Topics: Acetaminophen; Adult; Dicumarol; Female; Humans; Hypergammaglobulinemia; Hyperthyroidism; Immunoglobulin E; Leg; Orphenadrine; Pigmentation Disorders; Thyroid Hormones | 1978 |
Orphenadrine citrate increases and prolongs the antinociceptive effects of paracetamol in mice.
Topics: Acetaminophen; Animals; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Male; Mice; Orphenadrine; Pain; Time Factors | 1986 |
[Lumbagos and their drug therapy with Norflex and Norgesic].
Topics: Acetaminophen; Adult; Back Pain; Female; Humans; Male; Orphenadrine | 1970 |
[Therapeutic experiences with a myotinolytic agent (orphenadrine citrate) in vertebral, radicular disorders].
Topics: Acetaminophen; Cervical Vertebrae; Citrates; Humans; Lumbar Vertebrae; Myotonia; Orphenadrine; Peripheral Nervous System Diseases; Radiculopathy; Spinal Nerve Roots; Whiplash Injuries | 1973 |
Efficiency of a muscle relaxant-analgesic combination in general practice.
Topics: Acetaminophen; Humans; Muscles; Orphenadrine; Pain | 1967 |
Phenylbutazone, musculoskeletal disease, and leukemia.
Topics: Acetaminophen; Adrenal Cortex Hormones; Adult; Aged; Bone Diseases; Delivery of Health Care; Diazepam; Female; Humans; Leukemia; Leukemia, Myeloid; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Middle Aged; Muscular Diseases; Orphenadrine; Phenylbutazone; Risk | 1982 |
EXPERIENCES WITH A MUSCLE RELAXANT-ANALGESIC COMBINATION IN GENERAL PRACTICE.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Family Practice; General Practice; Humans; Muscle Cramp; Orphenadrine; Statistics as Topic | 1963 |
Determination of paracetamol and orphenadrine citrate in pharmaceutical tablets by modeling of spectrophotometric data using partial least-squares and artificial neural networks.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Chemistry, Pharmaceutical; Neural Networks, Computer; Neuromuscular Agents; Orphenadrine; Software; Spectrophotometry; Tablets | 2007 |
Application of normalized spectra in resolving a challenging Orphenadrine and Paracetamol binary mixture.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Drug Combinations; Linear Models; Muscle Relaxants, Central; Orphenadrine; Reproducibility of Results; Spectrophotometry | 2015 |
Fast determination of codeine, orphenadrine, promethazine, scopolamine, tramadol, and paracetamol in pharmaceutical formulations by capillary electrophoresis.
Topics: Acetaminophen; Codeine; Drug Compounding; Electrophoresis, Capillary; Orphenadrine; Promethazine; Scopolamine; Tramadol | 2017 |
Effect of Genetic Algorithm-Based Wavelength Selection as a Preprocessing Tool on Multivariate Simultaneous Determination of Paracetamol, Orphenadrine Citrate, and Caffeine in the Presence of p-Aminophenol Impurity.
Topics: Acetaminophen; Algorithms; Aminophenols; Caffeine; Calibration; Least-Squares Analysis; Orphenadrine | 2020 |
Different techniques for overlapped UV spectra resolution of some co-administered drugs with paracetamol in their combined pharmaceutical dosage forms.
Topics: Acetaminophen; Caffeine; Diclofenac; Linear Models; Models, Chemical; Orphenadrine; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 2020 |
Development and Validation of Chromatographic Methods for Simultaneous Determination of Paracetamol, Orphenadrine Citrate and Caffeine in Presence of P-aminophenol; Quantification of P-aminophenol Nephrotoxic Impurity Using LC-MS/MS.
Topics: Acetaminophen; Aminophenols; Caffeine; Chromatography, High Pressure Liquid; Chromatography, Liquid; Chromatography, Reverse-Phase; Chromatography, Thin Layer; Densitometry; Drug Contamination; Excipients; Orphenadrine; Tablets; Tandem Mass Spectrometry | 2020 |
First report on the occurrence of pharmaceuticals and cocaine in the coastal waters of Santa Catarina, Brazil, and its related ecological risk assessment.
Topics: Acetaminophen; Atenolol; Brazil; Caffeine; Carbamazepine; Chromatography, Liquid; Cocaine; Cosmetics; Diclofenac; Ecosystem; Environmental Monitoring; Humans; Losartan; Orphenadrine; Pharmaceutical Preparations; Risk Assessment; Sewage; Solid Waste; Tandem Mass Spectrometry; Water; Water Pollutants, Chemical | 2022 |
Occurrence, ecological risk assessment and prioritization of pharmaceuticals and abuse drugs in estuarine waters along the São Paulo coast, Brazil.
Topics: Acetaminophen; Atenolol; Brazil; Caffeine; Carbamazepine; Chromatography, Liquid; Cocaine; Diclofenac; Ecosystem; Environmental Monitoring; Furosemide; Illicit Drugs; Losartan; Orphenadrine; Pharmaceutical Preparations; Risk Assessment; Rivers; Tandem Mass Spectrometry; Water Pollutants, Chemical | 2022 |