acetaminophen has been researched along with nitrophenols in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (33.33) | 18.7374 |
| 1990's | 14 (46.67) | 18.2507 |
| 2000's | 4 (13.33) | 29.6817 |
| 2010's | 1 (3.33) | 24.3611 |
| 2020's | 1 (3.33) | 2.80 |
| Authors | Studies |
|---|---|
| Dawson, J; Knowles, RG; Pogson, CI | 3 |
| Horikoshi, I; Komori, M; Mizuma, T; Ueno, M | 1 |
| Bartolone, JB; Beierschmitt, WP; Cohen, SD; Emeigh Hart, SG; Khairallah, EA; Wyand, DS | 1 |
| Bement, WJ; Guzelian, PS; Lambrecht, LK; McCaffrey, J; Park, SS; Schenkman, JB; Sinclair, JF; Sinclair, PR; Smith, EL; Wood, SG | 1 |
| Gorman, N; Hunt, J; Lambrecht, L; Mende-Mueller, L; Sinclair, JF; Sinclair, P; Smith, L; Wood, S | 1 |
| Corcoran, GB; Wong, BK | 1 |
| Araya, H; Awazu, S; Hayashi, M; Horie, T; Mizuma, T | 1 |
| Bernstein, J; DeShone, GM; Hoefle, D; Hook, JB; Kuo, CH; Newton, JF | 1 |
| LeValley, SE; Mitoma, C | 1 |
| Meerman, JH; Mulder, GJ | 1 |
| Bonham Carter, SM; Caldwell, J; Glover, V; Rein, G; Sandler, M | 1 |
| Glover, V; Sandler, M; Sodha, RJ | 1 |
| Araya, H; Awazu, S; Hayashi, M; Mizuma, T | 1 |
| Bond, JA; Chism, JP; Long, RM; Rickert, DE | 1 |
| Knight, BI; Skellern, GG | 1 |
| Mugford, CA; Tarloff, JB | 1 |
| Raiford, DS; Thigpen, MC | 1 |
| Eyer, P; Koebe, HG; Pahernik, S; Schildberg, FW | 1 |
| Dalhoff, K; Poulsen, HE | 1 |
| Cederbaum, AI; Dai, Y | 1 |
| Awazu, S; Mizuma, T | 1 |
| Galchev, V; Kindt, E; Kostrubsky, VE; Ramachandran, V; Rose, K; Sinclair, JF; Sinz, M; Strom, SC; Venkataramanan, R; Wen, YH | 1 |
| Esumi, H; Higaki, K; Ishii, M; Kanayama, M; Kimura, T; Ogawara, KI | 2 |
| Fang, Y; Liu, C; Yu, Y; Zhou, B | 1 |
| Kim, SJ; Kim, SY; Kim, YC; Kwon, DY; Lee, MY | 1 |
| Commandeur, JN; den Braver, MW; den Braver-Sewradj, SP; Richert, L; Vermeulen, NP; Vos, JC | 1 |
| Hamdy, AM; Ibrahim, H; Merey, HA; Saad, AS | 1 |
1 review(s) available for acetaminophen and nitrophenols
| Article | Year |
|---|---|
Sulfation and glucuronidation as competing pathways in the metabolism of hydroxamic acids: the role of N,O-sulfonation in chemical carcinogenesis of aromatic amines.
Topics: Acetaminophen; Amines; Animals; Binding Sites; Biological Availability; Carcinogens; Diet; Glucuronates; Glutathione; Hydroxamic Acids; Nitrophenols; Pentachlorophenol; Rats; Sulfates; Urinary Bladder Neoplasms | 1983 |
29 other study(ies) available for acetaminophen and nitrophenols
| Article | Year |
|---|---|
Measurement of glucuronidation by isolated rat liver cells using [14C]fructose.
Topics: Acetaminophen; Animals; Carbon Radioisotopes; Cells, Cultured; Chromatography, High Pressure Liquid; Fructose; Glucosyltransferases; Glucuronates; Glucuronosyltransferase; Kinetics; Liver; Male; Naphthols; Nitrophenols; Rats; Rats, Inbred Strains | 1992 |
Sulphate conjugation enhances reversible binding of drug to human serum albumin.
Topics: Acetaminophen; Chromatography, High Pressure Liquid; Humans; Naphthols; Naproxen; Nitrophenols; Pharmaceutical Preparations; Protein Binding; Serum Albumin; Sulfates | 1991 |
Evidence against deacetylation and for cytochrome P450-mediated activation in acetaminophen-induced nephrotoxicity in the CD-1 mouse.
Topics: Acetaminophen; Acetylation; Aminophenols; Animals; Blood Urea Nitrogen; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Kidney Diseases; Kidney Tubular Necrosis, Acute; Kidney Tubules, Proximal; Male; Mice; Nitrophenols; Piperonyl Butoxide; Proteins; Tritolyl Phosphates | 1991 |
Ethanol increases cytochromes P450IIE, IIB1/2, and IIIA in cultured rat hepatocytes.
Topics: Acetaminophen; Animals; Cells, Cultured; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Dexamethasone; Ethanol; Hydroxylation; Liver; Male; Nitrophenols; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains; Troleandomycin | 1991 |
Quantitative studies of sulphate conjugation by isolated rat liver cells using [35S]sulphate.
Topics: Acetaminophen; Animals; Barium; Cells, Cultured; Chromatography, High Pressure Liquid; Glucuronates; Kinetics; Liver; Male; Naphthols; Nitrophenols; Rats; Sulfates; Sulfur Radioisotopes | 1991 |
Determination of glucuronidation in isolated rat liver cells by incorporation of 14C from fructose.
Topics: Acetaminophen; Animals; Carbon Radioisotopes; Fructose; Glucuronates; In Vitro Techniques; Liver; Male; Naphthols; Nitrophenols; Rats; Rats, Inbred Strains | 1990 |
Isolation of four forms of acetone-induced cytochrome P-450 in chicken liver by h.p.l.c. and their enzymic characterization.
Topics: Acetaminophen; Acetone; Amino Acid Sequence; Animals; Benzphetamine; Catalysis; Chick Embryo; Chickens; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Ethanol; Glutethimide; Liver; Molecular Sequence Data; Molecular Weight; Nitrophenols; Substrate Specificity | 1990 |
Effects of esterase inhibitors and buthionine sulfoximine on the prevention of acetaminophen hepatotoxicity by N-acetylcysteine.
Topics: Acetaminophen; Acetylcysteine; Animals; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Esterases; Isoflurophate; Lysine; Male; Methionine Sulfoximine; Mice; Mice, Inbred ICR; Nitrophenols; Organophosphorus Compounds; Phenylmethylsulfonyl Fluoride | 1987 |
Heterogeneous distribution of the conjugation activity of acetaminophen and p-nitrophenol in isolated rat liver cells.
Topics: Acetaminophen; Animals; Cell Fractionation; Glucuronates; Harmine; In Vitro Techniques; Liver; Male; Nitrophenols; Rats; Rats, Inbred Strains; Sulfates | 1986 |
The role of p-aminophenol in acetaminophen-induced nephrotoxicity: effect of bis(p-nitrophenyl) phosphate on acetaminophen and p-aminophenol nephrotoxicity and metabolism in Fischer 344 rats.
Topics: Acetaminophen; Aminophenols; Animals; Body Weight; Injections, Intraperitoneal; Kidney Cortex Necrosis; Male; Nitrophenols; Organ Size; Rats; Rats, Inbred F344 | 1985 |
Effect on newborn rats of perinatal exposure to phenobarbital.
Topics: Acetaminophen; Animals; Animals, Newborn; Antipyrine; Brain; Female; Hexobarbital; Microsomes, Liver; Nitrophenols; Phenobarbital; Pregnancy; Pyrazoles; Rats; Sleep; Spectrophotometry | 1970 |
Human platelet phenolsulphotransferase M and P: substrate specificities and correlation with in vivo sulphoconjugation of paracetamol and salicylamide.
Topics: Acetaminophen; Arylsulfotransferase; Blood Platelets; Humans; Isoenzymes; Kinetics; Nitrophenols; Salicylamides; Substrate Specificity; Sulfurtransferases | 1983 |
Phenolsulphotransferase in human placenta.
Topics: Acetaminophen; Arylsulfotransferase; Female; Humans; Nitrophenols; Placenta; Pregnancy; Salicylamides; Sulfurtransferases | 1983 |
Multiple forms of aryl sulfotransferase for acetaminophen sulfate conjugation in rat liver cytosol.
Topics: Acetaminophen; Animals; Arylsulfotransferase; Cytosol; Drug Stability; Hydrogen-Ion Concentration; In Vitro Techniques; Isoenzymes; Kinetics; Liver; Nitrophenols; Rats; Rats, Inbred Strains; Sulfurtransferases; Temperature | 1984 |
Metabolism and excretion of nitrobenzene by rats and mice.
Topics: Acetaminophen; Administration, Oral; Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Feces; Injections, Intraperitoneal; Male; Mice; Mixed Function Oxygenases; Nitrobenzenes; Nitrophenols; Rats; Rats, Inbred F344; Species Specificity | 1983 |
Measurement of the formation of paracetamol and p-nitrophenol glucuronides in vitro, by ion-pair high-performance liquid chromatography.
Topics: Acetaminophen; Animals; Chromatography, High Pressure Liquid; Glucuronates; Guinea Pigs; Microsomes, Liver; Nitrophenols | 1980 |
Contribution of oxidation and deacetylation to the bioactivation of acetaminophen in vitro in liver and kidney from male and female Sprague-Dawley rats.
Topics: Acetaminophen; Animals; Biotransformation; Carbon Radioisotopes; Female; Kidney; Kidney Diseases; Liver; Male; Nitrophenols; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Sex Factors; Triazoles | 1995 |
Kupffer cell stimulation with Corynebacterium parvum reduces some cytochrome P450-dependent activities and diminishes acetaminophen and carbon tetrachloride-induced liver injury in the rat.
Topics: Acetaminophen; Alanine Transaminase; Animals; Biotransformation; Carbon Tetrachloride; Cells, Cultured; Coumarins; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Galactosamine; Glutathione; Immunization; Kupffer Cells; Liver; Male; Microsomes, Liver; Nitrophenols; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Propionibacterium acnes; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence | 1994 |
Collagen gel immobilization: a useful cell culture technique for long-term metabolic studies on human hepatocytes.
Topics: Acetaminophen; Adult; Aged; Anisoles; Biotransformation; Cell Separation; Cell Survival; Cells, Cultured; Collagen; Culture Media; Cytochrome P-450 Enzyme System; DNA; Extracellular Matrix; Female; Gels; Glucuronates; Humans; Liver; Nitrophenols; Sulfates | 1994 |
Simultaneous measurements of glutathione and activated sulphate (PAPS) synthesis rates and the effects of selective inhibition of glutathione conjugation or sulphation of acetaminophen.
Topics: Acetaminophen; Animals; Buthionine Sulfoximine; Cells, Cultured; Female; Glutathione; Liver; Methionine Sulfoximine; Nitrophenols; Phosphoadenosine Phosphosulfate; Rats; Rats, Wistar; Sulfates; Sulfotransferases | 1993 |
Inactivation and degradation of human cytochrome P4502E1 by CCl4 in a transfected HepG2 cell line.
Topics: Acetaminophen; Carbon Tetrachloride; Cell Line; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Gene Expression Regulation, Enzymologic; Humans; Hydrolysis; Microsomes; Nitrophenols; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Tetradecanoylphorbol Acetate; Transfection | 1995 |
Inhibitory effect of phloridzin and phloretin on glucuronidation of p-nitrophenol, acetaminophen and 1-naphthol: kinetic demonstration of the influence of glucuronidation metabolism on intestinal absorption in rats.
Topics: Acetaminophen; Animals; Chromatography, High Pressure Liquid; Glucuronates; Glucuronidase; Intestinal Absorption; Male; Naphthols; Nitrophenols; Phloretin; Phlorhizin; Rats; Rats, Wistar | 1998 |
The role of conjugation in hepatotoxicity of troglitazone in human and porcine hepatocyte cultures.
Topics: Acetaminophen; Animals; Cells, Cultured; Chromans; Dose-Response Relationship, Drug; Hepatocytes; Humans; Nitrophenols; Pentachlorophenol; Phenobarbital; Protein Biosynthesis; Proteins; Swine; Thiazoles; Thiazolidinediones; Troglitazone | 2000 |
Pharmacokinetic analysis of factors determining elimination pathways for sulfate and glucuronide metabolites of drugs. I: studies by in vivo constant infusion.
Topics: Acetaminophen; Animals; Glucuronides; Hymecromone; Infusions, Intravenous; Kidney; Kinetics; Liver; Male; Nitrophenols; Pharmaceutical Preparations; Rats; Rats, Wistar; Sulfates | 2002 |
Pharmacokinetic analysis of factors determining elimination pathways for sulfate and glucuronide metabolites of xenobiotics II: Studies with isolated perfused rat liver.
Topics: Acetaminophen; Animals; Bile; Glucuronides; Hymecromone; In Vitro Techniques; Liver; Male; Nitrophenols; Protein Binding; Rats; Rats, Wistar; Serum Albumin, Bovine; Sulfates; Xenobiotics | 2003 |
[Research into determination of tricomponent sample by ridge regression spectrophotometry].
Topics: Acetaminophen; Aminophenols; Analgesics, Non-Narcotic; Nitrophenols; Spectrophotometry | 1999 |
Alteration in metabolism and toxicity of acetaminophen upon repeated administration in rats.
Topics: Acetaminophen; Alanine Transaminase; Aminopyrine; Analgesics, Non-Narcotic; Animals; Anisoles; Aspartate Aminotransferases; Cysteine; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Injections, Intraperitoneal; L-Iditol 2-Dehydrogenase; Liver; Microsomes, Liver; Nitrophenols; Rats; Rats, Sprague-Dawley | 2009 |
Inter-donor variability of phase I/phase II metabolism of three reference drugs in cryopreserved primary human hepatocytes in suspension and monolayer.
Topics: Acetaminophen; Aged; Benzophenones; Cells, Cultured; Cryopreservation; Cytochrome P-450 Enzyme System; Diclofenac; Female; Glucuronosyltransferase; Hepatocytes; Humans; Male; Middle Aged; Nitrophenols; Sulfotransferases; Tolcapone; Umbelliferones | 2016 |
Simultaneous Determination of Paracetamol, Propyphenazone and Caffeine in Presence of Paracetamol Impurities Using Dual-Mode Gradient HPLC and TLC Densitometry Methods.
Topics: Acetaminophen; Aminophenols; Antipyrine; Caffeine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Codeine; Densitometry; Drug Combinations; Drug Contamination; Limit of Detection; Meprobamate; Nitrophenols; Reproducibility of Results; Sensitivity and Specificity; Solvents; Tablets | 2021 |