Compounds > acetaminophen

acetaminophen and n-pentanol

acetaminophen has been researched along with n-pentanol in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's4 (80.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bement, WJ; Bush, MD; Jeffery, EH; Kostrubsky, VE; Sinclair, JF; Sinclair, PR; Szakacs, J; Wood, SG1
Bement, WJ; Jeffery, EH; Kostrubsky, VE; Sinclair, JF; Sinclair, PR; Szakacs, JG; Wood, SG; Wright, D; Wrighton, SA1
Bement, JL; Bement, WJ; Gonzalez, FJ; Jeffery, EH; Sinclair, JF; Sinclair, PR; Szakacs, JG; Walton, HS; Wood, SG; Wrighton, SA1
Bement, J; Chatfield, K; DiPetrillo, K; Jeffery, E; Kostrubsky, V; Sinclair, J; Sinclair, P; Wood, S; Wrighton, S1
Allard, JL; Court, MH; Duan, SX; Gonzalez, FJ; Gorman, N; Greenblatt, DJ; Hao, Q; Hunt, JA; Jeffery, EH; Kostrubsky, V; Sinclair, JF; Sinclair, PR; Szakacs, JG; von Moltke, LL; Walton-Strong, BW; Wolf, KK; Wood, SG; Wrighton, SA1

Other Studies

5 other study(ies) available for acetaminophen and n-pentanol

ArticleYear
Acute hepatotoxicity of acetaminophen in rats treated with ethanol plus isopentanol.
    Biochemical pharmacology, 1995, Nov-27, Volume: 50, Issue:11

    Topics: Acetaminophen; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Drug Interactions; Ethanol; Glutathione; Liver; Male; Necrosis; Pentanols; Rats; Rats, Inbred F344; Time Factors

1995
Acetaminophen hepatotoxicity precipitated by short-term treatment of rats with ethanol and isopentanol: protection by triacetyloleandomycin.
    Biochemical pharmacology, 2000, Feb-15, Volume: 59, Issue:4

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Aryl Hydrocarbon Hydroxylases; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Ethanol; Liver Diseases; Male; Oxidoreductases, N-Demethylating; Pentanols; Protective Agents; Rats; Rats, Inbred F344; Troleandomycin

2000
Short-term treatment with alcohols causes hepatic steatosis and enhances acetaminophen hepatotoxicity in Cyp2e1(-/-) mice.
    Toxicology and applied pharmacology, 2000, Oct-15, Volume: 168, Issue:2

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Benzoquinones; Biotransformation; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Drug Synergism; Ethanol; Fatty Liver, Alcoholic; Female; Imines; Liver; Liver Diseases; Male; Mice; Mice, Inbred C57BL; Pentanols; Sex Factors

2000
Effect of caffeine on acetaminophen hepatotoxicity in cultured hepatocytes treated with ethanol and isopentanol.
    Toxicology and applied pharmacology, 2002, Dec-01, Volume: 185, Issue:2

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Aryl Hydrocarbon Hydroxylases; Caffeine; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Drug Synergism; Enzyme Inhibitors; Ethanol; Hepatocytes; Oxidoreductases, N-Demethylating; Pentanols; Rats; Troleandomycin

2002
Role of CYP3A and CYP2E1 in alcohol-mediated increases in acetaminophen hepatotoxicity: comparison of wild-type and Cyp2e1(-/-) mice.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:7

    Topics: Acetaminophen; Alanine Transaminase; Animals; Benzoquinones; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Disease Models, Animal; Drug Synergism; Enzyme Induction; Enzyme Inhibitors; Ethanol; Glucuronides; Glutathione; Hydroxylation; Imines; Liver; Liver Diseases; Male; Mice; Mice, Knockout; Pentanols; Severity of Illness Index; Testosterone; Troleandomycin

2007