acetaminophen and n,n'-bis(pyridoxal-5-phosphate)ethylenediamine-n,n'-diacetic acid

acetaminophen has been researched along with n,n'-bis(pyridoxal-5-phosphate)ethylenediamine-n,n'-diacetic acid in 8 studies

Research

Studies (8)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (12.50)	29.6817
2010's	5 (62.50)	24.3611
2020's	2 (25.00)	2.80

Authors

Authors	Studies
Batteux, F; Bedda, S; Calmus, Y; Chéreau, C; Conti, F; Goulvestre, C; Jaffray, P; Laurent, A; Soubrane, O; Tran, A; Tran-Van Nhieu, J; Weill, B	1
Dear, J	1
Ignarro, LJ; Jynge, P; Karlsson, JOG; Lundström, I	1
Black, P; Dear, JW; Gallagher, B; Grahamslaw, J; Henriksen, D; Lee, RJ; Morrison, EE; O'Brien, R; Oatey, K; Oosthuyzen, W; Weir, CJ	1
Karlsson, JOG	1
Dear, JW	1
Freeman, WE; Mullins, ME; Yeager, LH	1
Akakpo, JY; Jaeschke, H; Ramachandran, A	1

Reviews

2 review(s) available for acetaminophen and n,n'-bis(pyridoxal-5-phosphate)ethylenediamine-n,n'-diacetic acid

Article	Year
Metabolic and mitochondrial treatments for severe paracetamol poisoning: a systematic review. Clinical toxicology (Philadelphia, Pa.), 2020, Volume: 58, Issue:12 Topics: Acetaminophen; Acetylcysteine; Acidosis; Animals; Antidotes; Cimetidine; Drug Overdose; Edetic Acid; Fomepizole; Humans; Mitochondria; Pyridoxal Phosphate	2020
Novel strategies for the treatment of acetaminophen hepatotoxicity. Expert opinion on drug metabolism & toxicology, 2020, Volume: 16, Issue:11 Topics: Acetaminophen; Acetylcysteine; Animals; Antidotes; Chemical and Drug Induced Liver Injury; Drug Overdose; Edetic Acid; Fomepizole; Hepatocytes; Humans; Liver Failure, Acute; Pyridoxal Phosphate	2020

Trials

2 trial(s) available for acetaminophen and n,n'-bis(pyridoxal-5-phosphate)ethylenediamine-n,n'-diacetic acid

Article	Year
Randomised open label exploratory, safety and tolerability study with calmangafodipir in patients treated with the 12-h regimen of N-acetylcysteine for paracetamol overdose-the PP100-01 for Overdose of Paracetamol (POP) trial: study protocol for a randomi Trials, 2019, Jan-08, Volume: 20, Issue:1 Topics: Acetaminophen; Acetylcysteine; Chemical and Drug Induced Liver Injury; Clinical Trials Data Monitoring Committees; Clinical Trials, Phase I as Topic; Data Interpretation, Statistical; Drug Overdose; Drug Therapy, Combination; Edetic Acid; Female; Humans; Male; Outcome Assessment, Health Care; Pyridoxal Phosphate; Randomized Controlled Trials as Topic; Research Design	2019
Principal results of a randomised open label exploratory, safety and tolerability study with calmangafodipir in patients treated with a 12 h regimen of N-acetylcysteine for paracetamol overdose (POP trial). EBioMedicine, 2019, Volume: 46 Topics: Acetaminophen; Acetylcysteine; Adult; Biomarkers; Chemical and Drug Induced Liver Injury; Drug Interactions; Drug Overdose; Edetic Acid; Female; Humans; Male; Protective Agents; Pyridoxal Phosphate; Time Factors; Young Adult	2019

Article

Year

Randomised open label exploratory, safety and tolerability study with calmangafodipir in patients treated with the 12-h regimen of N-acetylcysteine for paracetamol overdose-the PP100-01 for Overdose of Paracetamol (POP) trial: study protocol for a randomi

Trials, 2019, Jan-08, Volume: 20, Issue:1

Topics: Acetaminophen; Acetylcysteine; Chemical and Drug Induced Liver Injury; Clinical Trials Data Monitoring Committees; Clinical Trials, Phase I as Topic; Data Interpretation, Statistical; Drug Overdose; Drug Therapy, Combination; Edetic Acid; Female; Humans; Male; Outcome Assessment, Health Care; Pyridoxal Phosphate; Randomized Controlled Trials as Topic; Research Design

2019

Principal results of a randomised open label exploratory, safety and tolerability study with calmangafodipir in patients treated with a 12 h regimen of N-acetylcysteine for paracetamol overdose (POP trial).

EBioMedicine, 2019, Volume: 46

Topics: Acetaminophen; Acetylcysteine; Adult; Biomarkers; Chemical and Drug Induced Liver Injury; Drug Interactions; Drug Overdose; Edetic Acid; Female; Humans; Male; Protective Agents; Pyridoxal Phosphate; Time Factors; Young Adult

2019

Other Studies

4 other study(ies) available for acetaminophen and n,n'-bis(pyridoxal-5-phosphate)ethylenediamine-n,n'-diacetic acid

Article	Year
Mangafodipir prevents liver injury induced by acetaminophen in the mouse. Journal of hepatology, 2003, Volume: 39, Issue:5 Topics: Acetaminophen; Animals; Antibodies, Monoclonal; Antioxidants; Carcinoma, Hepatocellular; Caspase 3; Caspase Inhibitors; Cell Line, Tumor; Cytochromes c; Edetic Acid; Enzymes; fas Receptor; Female; Glutathione; Humans; Liver; Liver Failure, Acute; Liver Neoplasms; Mice; Mice, Inbred BALB C; Oxidoreductases; Pyridoxal Phosphate; Reactive Oxygen Species; Superoxides; Survival Analysis	2003
Letter in response to: "Randomised open label exploratory, safety and tolerability study with calmangafodipir in patients treated with the 12-h regimen of N acetylcysteine for paracetamol overdose-the PP100-01 for Overdose of Paracetamol (POP) trial: stud Trials, 2019, 06-24, Volume: 20, Issue:1 Topics: Acetaminophen; Acetylcysteine; Drug Overdose; Edetic Acid; Humans; Pyridoxal Phosphate; Research Design	2019
Gastrointestinal AEs seen in the POP trial due to SOD mimetic activity of calmangafodipir? EBioMedicine, 2019, Volume: 47 Topics: Acetaminophen; Acetylcysteine; Edetic Acid; Humans; Pyridoxal Phosphate; Superoxide Dismutase	2019
Gastrointestinal AEs seen in the POP trial due to SOD mimetic activity of calmangafodipir? - Authors' reply. EBioMedicine, 2019, Volume: 47 Topics: Acetaminophen; Acetylcysteine; Edetic Acid; Humans; Pyridoxal Phosphate; Superoxide Dismutase	2019