acetaminophen has been researched along with midazolam in 48 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 4 (8.33) | 18.2507 |
2000's | 19 (39.58) | 29.6817 |
2010's | 18 (37.50) | 24.3611 |
2020's | 7 (14.58) | 2.80 |
Authors | Studies |
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Topliss, JG; Yoshida, F | 1 |
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Critchley, JA; Gin, T; McArthur, CJ; McLaren, IM; Oh, TE | 1 |
Charest, J; Vischoff, D | 1 |
Hofstadter, MB; Kain, ZN; Mayes, LC; Wang, SM | 1 |
Payne, KA; Roelofse, JA | 1 |
Dahl, V; Fjellanger, F; Raeder, JC | 1 |
Calderon, PB; Delzenne, N; Eeckhoudt, SL; Horsmans, Y; Martiat, GA; Taper, HS; Vanhulle, VP; Verbeeck, RK | 1 |
Calderon, PB; Evdokimova, E; Taper, H | 1 |
Riedl, B | 1 |
Franssila, S; Grigoras, K; Huikko, K; Kostiainen, R; Kotiaho, T; Mandel, F; Östman, P; Sauber, C | 1 |
Becker, RS; Gartner, CA; Gygi, SP; Jones, G; Nelson, SD; Wan, J; Wen, B | 1 |
Buffett-Jerrott, S; Finley, GA; Millington, D; Stewart, SH; Wright, KD | 1 |
Duzenli, VE; Katircioglu, K; Ozkalkanli, MY; Savaci, S; Unal, I | 1 |
Anderson, BJ; Mathot, RA; Prins, SA; Searle, S; Tibboel, D; Van Dijk, M; Van Leeuwen, P | 1 |
García Saura, PL; Lorite Rascón, A; Martínez Gámez, J; Parras Maldonado, MT; Ramos Lozano, R | 1 |
Chandra, A; Colborn, DK; Hoberman, A; Hooper, EG; Kurs-Lasky, M; Reis, EC; Rockette, HE; Shaikh, N | 1 |
Allegaert, K; Thewissen, L | 1 |
Badmaev, V; Court, MH; Greenblatt, DJ; Hanley, MJ; Harmatz, JS; Hazarika, S; Majeed, M; Masse, G; Volak, LP | 1 |
Mankes, RF; Silver, CD | 1 |
Arakawa, H; Ikeya, T; Inoue, Y; Iwai, H; Jomura, T; Koeda, A; Kusumoto, K; Nagao, T; Naitoh, K; Ogihara, T; Ohkura, T; Ohta, K; Ozeki, E; Takahashi, N; Ueda, T; Wada, K | 1 |
Casavant, MJ; Gerona, RR; Ho, RY; Russell, JL; Spiller, HA | 1 |
Berben, SA; Doggen, CJ; Gaakeer, MI; IJzerman, MJ; Pierik, JG; van Eenennaam, FL; van Vugt, AB | 1 |
Fortier, MA; Jenkins, B; Kain, ZN; Min, CB; Stevenson, RS | 1 |
Arakawa, H; Itoh, M; Kojima, H; Koyama, S; Masuda, N; Ogihara, T; Yano, K | 1 |
Couret, C; Ducloyer, JB; Le Meur, G; Lebranchu, P; Lejus-Bourdeau, C; Magne, C; Weber, M | 1 |
Benahmed-Canat, A; Canat, G; Claris, O; Kassai, B; Nguyen, KA; Paret, N; Plaisant, F; Rabilloud, M; Riche, B | 1 |
Allorto, NL; Clarke, DL; Wall, SL | 1 |
Donato, J; Lewis, T; Rao, K | 1 |
Al Sayegh, R; Carr, MM; Ellison, PR; Roberts, C; Sedeek, K | 1 |
Bao, Y; Ma, X; Manautou, JE; Shao, X; Shi, J; Wang, P; Xiao, J; Zhang, L; Zhong, XB; Zhu, HJ; Zhu, J | 1 |
Chan, LN; Chen, KF; Lin, YS | 1 |
Fumoto, S; Miyamoto, H; Nishida, K; Tokunaga, A | 1 |
Bao, Y; Ma, X; Manautou, JE; Phan, M; Zhong, XB; Zhu, J | 1 |
Dong, YY; Huang, CK; Lang, LP; Li, QQ; Qian, JC; Sun, W; Wang, Z; Zhang, XD | 1 |
Banzi, R; Bruschettini, M; Calevo, MG; Ley, D; Paraskevas, T; Romantsik, O; Stróżyk, A | 1 |
4 review(s) available for acetaminophen and midazolam
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Analgosedation in neonates: do we still need additional tools after 30 years of clinical research?
Topics: Acetaminophen; Adrenergic alpha-2 Receptor Agonists; Analgesia; Analgesics, Opioid; Dexmedetomidine; Humans; Hypnotics and Sedatives; Infant, Newborn; Midazolam; Morphine; Pain; Pain Measurement; Piperidines; Propofol; Quality of Health Care; Remifentanil | 2011 |
Pharmacology of Common Analgesic and Sedative Drugs Used in the Neonatal Intensive Care Unit.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Combined Modality Therapy; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Sedatives; Infant, Newborn; Intensive Care Units, Neonatal; Midazolam; Morphine; Pain; Pain Management; Pharmacogenomic Variants; Precision Medicine; Remifentanil | 2019 |
Pharmacological pain and sedation interventions for the prevention of intraventricular hemorrhage in preterm infants on assisted ventilation - an overview of systematic reviews.
Topics: Acetaminophen; Analgesics, Opioid; Cerebral Hemorrhage; Female; Heroin; Humans; Ibuprofen; Infant, Newborn; Infant, Premature; Midazolam; Pain; Perinatal Death; Phenobarbital; Respiration, Artificial; Systematic Reviews as Topic | 2023 |
9 trial(s) available for acetaminophen and midazolam
Article | Year |
---|---|
Gastric emptying following brain injury: effects of choice of sedation and intracranial pressure.
Topics: Acetaminophen; Adult; Brain Injuries; Conscious Sedation; Drug Therapy, Combination; Female; Gastric Emptying; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Morphine; Narcotics; Propofol; Prospective Studies; Pseudotumor Cerebri | 1995 |
Postoperative behavioral outcomes in children: effects of sedative premedication.
Topics: Acetaminophen; Administration, Oral; Anesthesia, General; Anesthetics, Intravenous; Anti-Anxiety Agents; Behavior; Child; Child, Preschool; Double-Blind Method; Humans; Midazolam; Multivariate Analysis; Postoperative Complications | 1999 |
Oral tramadol: analgesic efficacy in children following multiple dental extractions.
Topics: Acetaminophen; Administration, Oral; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia Recovery Period; Anti-Anxiety Agents; Child; Child Behavior; Child, Preschool; Crying; Double-Blind Method; Female; Humans; Male; Midazolam; Pain Measurement; Pain, Postoperative; Placebos; Preanesthetic Medication; Premedication; Respiration; Tooth Extraction; Tramadol | 1999 |
No effect of preoperative paracetamol and codeine suppositories for pain after termination of pregnancies in general anaesthesia.
Topics: Abortion, Induced; Acetaminophen; Adult; Alfentanil; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Anesthetics, Intravenous; Codeine; Dilatation and Curettage; Double-Blind Method; Drug Administration Schedule; Female; Humans; Midazolam; Pain Measurement; Pain, Postoperative; Pregnancy; Propofol; Suppositories | 2000 |
High levels of impulsivity may contraindicate midazolam premedication in children.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analysis of Variance; Anesthesia; Anesthetics, Intravenous; Anxiety; Child; Child Behavior; Child, Preschool; Contraindications; Double-Blind Method; Female; Humans; Impulsive Behavior; Male; Midazolam; Severity of Illness Index; Temperament | 2006 |
Pharmacokinetics and analgesic effects of intravenous propacetamol vs rectal paracetamol in children after major craniofacial surgery.
Topics: Acetaminophen; Administration, Rectal; Analgesia; Analgesics; Anesthetics, Intravenous; Child, Preschool; Craniofacial Abnormalities; Double-Blind Method; Female; Humans; Infant; Infusions, Intravenous; Male; Midazolam; Pain Measurement; Pain, Postoperative; Placebos; Treatment Outcome | 2008 |
Pain management in young children undergoing diagnostic tympanocentesis.
Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Analgesics, Opioid; Biopsy, Fine-Needle; Child, Preschool; Codeine; Diagnostic Techniques, Otological; Drug Administration Schedule; Drug Therapy, Combination; Ear, Middle; Female; Humans; Hypnotics and Sedatives; Ibuprofen; Infant; Male; Midazolam; Otitis Media; Pain; Pain Measurement; Treatment Outcome; Tympanic Membrane | 2011 |
Effect of a herbal extract containing curcumin and piperine on midazolam, flurbiprofen and paracetamol (acetaminophen) pharmacokinetics in healthy volunteers.
Topics: Acetaminophen; Alkaloids; Analgesics, Non-Narcotic; Area Under Curve; Benzodioxoles; Chromatography, High Pressure Liquid; Cross-Over Studies; Curcuma; Curcumin; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Double-Blind Method; Drug Interactions; Enzyme Inhibitors; Flurbiprofen; Half-Life; Humans; Hypnotics and Sedatives; Midazolam; Piperidines; Plant Extracts; Polyunsaturated Alkamides | 2013 |
A randomized trial examining preoperative sedative medication and postoperative sleep in children.
Topics: Acetaminophen; Actigraphy; Adenoidectomy; Child; Child, Preschool; Female; Humans; Hypnotics and Sedatives; Male; Midazolam; Postoperative Period; Preoperative Care; Sleep; Tonsillectomy | 2016 |
35 other study(ies) available for acetaminophen and midazolam
Article | Year |
---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Propofol for pulsed dye laser treatments in paediatric outpatients.
Topics: Acetaminophen; Anesthesia Recovery Period; Anesthesia, Intravenous; Child; Child, Preschool; Facial Dermatoses; Fentanyl; Hamartoma; Humans; Infant; Laser Coagulation; Midazolam; Pain, Postoperative; Propofol; Psychomotor Agitation | 1994 |
Cryopreservation of rat precision-cut liver slices by ultrarapid freezing: influence on phase I and II metabolism and on cell viability upon incubation for 24 hours.
Topics: Acetaminophen; Adenosine Triphosphate; Animals; Biotransformation; Blotting, Western; Cell Survival; Cryopreservation; Cytochrome P-450 Enzyme System; Freezing; Glycogen; Hepatocytes; Isoenzymes; L-Lactate Dehydrogenase; Liver; Male; Midazolam; Organ Culture Techniques; Organ Preservation; Rats; Rats, Wistar | 2001 |
Effects of bacterial endotoxin (lipopolysaccharides) on survival and metabolism of cultured precision-cut rat liver slices.
Topics: Acetaminophen; Adenosine Triphosphate; Animals; Cell Survival; Dexamethasone; Dose-Response Relationship, Drug; Escherichia coli; Glutathione; In Vitro Techniques; L-Lactate Dehydrogenase; Lipopolysaccharides; Liver; Midazolam; Nitric Oxide; Nitrites; Proteins; Rats; Rats, Wistar | 2002 |
[A common emergency in childhood. Febrile convulsions -- what to do?].
Topics: Acetaminophen; Administration, Rectal; Age Factors; Analgesics, Non-Narcotic; Anticonvulsants; Clonazepam; Diagnosis, Differential; Diazepam; Female; Humans; Hypnotics and Sedatives; Infant; Midazolam; Recurrence; Seizures, Febrile; Time Factors | 2003 |
Feasibility of atmospheric pressure desorption/ionization on silicon mass spectrometry in analysis of drugs.
Topics: Acetaminophen; Air Ionization; Atmospheric Pressure; Carboxylic Acids; Ketoprofen; Mass Spectrometry; Midazolam; Molecular Structure; Naphthaleneacetic Acids; Naphthalenes; Naphthoquinones; Pharmaceutical Preparations; Propranolol; Silicon; Testosterone | 2003 |
Photochromic agents as tools for protein structure study: lapachenole is a photoaffinity ligand of cytochrome P450 3A4.
Topics: Acetaminophen; Aryl Hydrocarbon Hydroxylases; Benzopyrans; Benzoquinones; Binding Sites; Buffers; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Glutathione; Ligands; Midazolam; Nuclear Magnetic Resonance, Biomolecular; Oxidoreductases, N-Demethylating; Photoaffinity Labels; Photolysis; Recombinant Proteins; Ultraviolet Rays | 2005 |
Brachial plexus block for the child with Kartagener's syndrome.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthetics, Intravenous; Brachial Plexus; Child; Dextrocardia; Finger Phalanges; Fractures, Bone; Humans; Kartagener Syndrome; Male; Midazolam; Nerve Block; Radiography, Thoracic; Rare Diseases | 2008 |
[Endovascular treatment of a ruptured abdominal aorta aneurysm with local anesthesia, sedation and analgesia].
Topics: Acetaminophen; Analgesics; Anesthesia, General; Anesthesia, Local; Aortic Aneurysm, Abdominal; Aortic Rupture; Blood Vessel Prosthesis Implantation; Erythrocyte Transfusion; Fentanyl; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Morphine; Piperidines; Plasma; Pulmonary Disease, Chronic Obstructive; Radiography, Interventional; Remifentanil; Stents | 2009 |
Quantitative study of controlled substance bedside wasting, disposal and evaluation of potential ecologic effects.
Topics: Acetaminophen; Codeine; Controlled Substances; Drug Combinations; Ecotoxicology; Fentanyl; Hospitals; Hydrocodone; Ketamine; Medical Waste Disposal; Midazolam; Morphine; New York; Oxycodone; Wastewater | 2013 |
Evaluation of human hepatocytes cultured by three-dimensional spheroid systems for drug metabolism.
Topics: Acetaminophen; Albuterol; Chromatography, Liquid; Cytochrome P-450 Enzyme System; Diclofenac; Glucuronosyltransferase; Hepatocytes; Humans; Lamotrigine; Midazolam; Pharmaceutical Preparations; Propranolol; Spheroids, Cellular; Tandem Mass Spectrometry; Triazines | 2014 |
Identification of N-Hydroxy-para-aminobenzoic acid in a cyanotic child after benzocaine exposure.
Topics: 4-Aminobenzoic Acid; Acetaminophen; Administration, Topical; Benzocaine; Bupivacaine; Child; Cyanosis; Dose-Response Relationship, Drug; Humans; Hydroxylamines; Lidocaine; Male; Methemoglobinemia; Methylene Blue; Midazolam; para-Aminobenzoates | 2014 |
A nurse-initiated pain protocol in the ED improves pain treatment in patients with acute musculoskeletal pain.
Topics: Acetaminophen; Adult; Analgesics; Diclofenac; Emergency Service, Hospital; Female; Fentanyl; Follow-Up Studies; Guidelines as Topic; Humans; Male; Midazolam; Middle Aged; Morphine; Musculoskeletal Pain; Netherlands; Pain Management; Patient Satisfaction; Time Factors; Tramadol | 2016 |
Evaluation of the metabolic capability of primary human hepatocytes in three-dimensional cultures on microstructural plates.
Topics: Acetaminophen; Adenosine Triphosphate; Arylsulfotransferase; Cell Culture Techniques; Cells, Cultured; Cytochrome P-450 Enzyme Inducers; Cytochrome P-450 Enzyme System; Diclofenac; Glucuronosyltransferase; Hepatocytes; Humans; Lamotrigine; Midazolam; Omeprazole; Rifampin; RNA, Messenger; Triazines | 2018 |
Prospective evaluation of anesthetic protocols during pediatric ophthalmic surgery.
Topics: Acetaminophen; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Intravenous; Anti-Anxiety Agents; Cataract; Child; Child, Preschool; Dexamethasone; Female; Glucocorticoids; Humans; Infant; Male; Midazolam; Ondansetron; Ophthalmologic Surgical Procedures; Pain, Postoperative; Postoperative Nausea and Vomiting; Propofol; Prospective Studies; Reflex, Oculocardiac; Strabismus; Vomiting | 2019 |
Postsurgery analgesic and sedative drug use in a French neonatal intensive care unit: A single-center retrospective cohort study.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Cohort Studies; Drug Utilization; Female; Fentanyl; France; Hospitals, University; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Intensive Care Units, Neonatal; Male; Midazolam; Morphine; Nalbuphine; Off-Label Use; Pain Measurement; Pain, Postoperative; Retrospective Studies; Substance Withdrawal Syndrome; Sufentanil; Urinary Retention | 2019 |
Analgesia protocols for burns dressings: Challenges with implementation.
Topics: Academic Medical Centers; Acetaminophen; Analgesics; Anesthetics, Inhalation; Bandages; Burns; Child; Clinical Competence; Fentanyl; Guideline Adherence; Hospitals, Community; Humans; Hypnotics and Sedatives; Ibuprofen; Ketamine; Methoxyflurane; Midazolam; Morphine; Pain Management; Pain Measurement; Pain, Procedural; Practice Guidelines as Topic; Practice Patterns, Physicians'; South Africa; Tertiary Care Centers; Tramadol | 2019 |
How Pediatric Anesthesiologists Manage Children with OSA Undergoing Tonsillectomy.
Topics: Acetaminophen; Adenoidectomy; Airway Extubation; Analgesics; Anesthesiology; Anesthetics; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Dexamethasone; Fentanyl; Humans; Midazolam; Morphine; Nitrous Oxide; Ondansetron; Pediatrics; Practice Guidelines as Topic; Practice Patterns, Physicians'; Sleep Apnea, Obstructive; Surveys and Questionnaires; Tonsillectomy | 2020 |
Acetaminophen-Induced Liver Injury Alters Expression and Activities of Cytochrome P450 Enzymes in an Age-Dependent Manner in Mouse Liver.
Topics: Acetaminophen; Adult; Age Factors; Animals; Chemical and Drug Induced Liver Injury; Child; Cytochrome P-450 Enzyme System; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Enzymologic; Humans; Infant; Liver; Male; Mice; Midazolam; Oxazines; Sex Factors | 2020 |
PBPK modeling of CYP3A and P-gp substrates to predict drug-drug interactions in patients undergoing Roux-en-Y gastric bypass surgery.
Topics: Acetaminophen; Administration, Oral; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; Biological Availability; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Digoxin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Gastric Bypass; Gastrointestinal Absorption; Hepatobiliary Elimination; Humans; Intestinal Elimination; Metabolic Clearance Rate; Midazolam; Models, Biological; Obesity, Morbid; Postoperative Period; Triazoles; Verapamil | 2020 |
Effect of Chronic Kidney Disease on Hepatic Clearance of Drugs in Rats.
Topics: Acetaminophen; Adenine; Administration, Intravenous; Animals; Cytochrome P-450 CYP3A; Disease Models, Animal; Glucuronosyltransferase; Hepatobiliary Elimination; Humans; Indocyanine Green; Kidney; Kidney Function Tests; Liver; Male; Metabolic Clearance Rate; Midazolam; Rats; Rats, Wistar; Renal Elimination; Renal Insufficiency, Chronic | 2020 |
Alterations of Cytochrome P450-Mediated Drug Metabolism during Liver Repair and Regeneration after Acetaminophen-Induced Liver Injury in Mice.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Cytochrome P-450 Enzyme System; Humans; Liver; Mice; Midazolam | 2022 |
Determination of CYP450 activities in diabetes mellitus rats by a UHPLC-MS/MS method.
Topics: Acetaminophen; Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Diabetes Mellitus, Experimental; Metoprolol; Midazolam; Phenacetin; Rats; Tandem Mass Spectrometry; Tolbutamide | 2023 |