acetaminophen and metoclopramide

acetaminophen has been researched along with metoclopramide in 81 studies

Research

Studies (81)

Timeframe	Studies, this research(%)	All Research%
pre-1990	23 (28.40)	18.7374
1990's	18 (22.22)	18.2507
2000's	17 (20.99)	29.6817
2010's	20 (24.69)	24.3611
2020's	3 (3.70)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Nimmo, WS; Prescott, LF; Wilson, J	1
Carter, DC; Heading, RC; Holt, S; Prescott, LF; Tothill, P	1
Krabbe, AA; Olesen, J; Veilis, B	1
Roberts, RH; Sinclair, SW; Tan, ST	1
Pradalier, A; Vincent, D	1
Moncrieff, J; Sommers, DK; van Wyk, M	2
Becker, A; Berner, G; Leuschner, F; Vögtle-Junkert, U	1
Ito, Y; Itoh, Z; Iwanaga, Y; Kato, H; Miyashita, N; Mizutani, F; Morikawa, K	1
Ho, ET; Kenny, GN; McNeill, MJ	1
Meyer, EC; Moncrieff, J; Sommers, DK; van Wyk, M	1
Bartlett, A; García-Barbal, J; Martínez, L; Roser, R; Sagarra, R; Sánchez, J	1
Howden, CW	1
Bamber, PA; Nimmo, WS; Rowbotham, DJ	1
Chen, JT; Fujimoto, I; Hamada, T; Hirai, Y; Katase, K; Nakayama, K; Shimizu, Y; Teshima, H; Yagi, H; Yamuchi, K	1
Tokola, RA	1
Dexter, SL; Graham, AN; Johnston, ES; Ratcliffe, DM; Rose, AJ; Wilkinson, MI	1
Wilkinson, M	2
Nimmo, J	1
Cameron, PF	1
Gardiner, J; Murphy, DF; Nally, B; Unwin, A	1
Boston, PF	1
Boston, PF; Matts, SG	1
Jensen, K; Lauritzen, M; Olesen, J; Tfelt-Hansen, P; Vendsborg, P	1
Blau, JN	1
Cunningham, B; Dougall, JR; Nimmo, WS	1
Behan, P	1
Aebelholt-Krabbe, A; Melgaard, B; Olesen, J; Tfelt-Hansen, P; Veilis, B	1
Olesen, J; Tfelt-Hansen, P	1
Harrop, C; Jones, A	1
Furst, SR; Rodarte, A	1
Moncrieff, J; Snyman, JR; Sommers, DK; van Wyk, M	1
Graf, WD; Riback, PS	1
Chrubasik, J; Chrubasik, S	1
Buss, DC; Cassidy, SL; Hale, A; Routledge, PA	1
Layton, G; Peck, RW; Posner, J; Ridout, G; Seaber, EJ	1
Andrews, FM; Doherty, TJ; Frazier, DL; Provenza, MK	1
Abraha, TW; Andrews, FM; Doherty, TJ; Frazier, DL; Osborne, D	1
Anderson, AC; Lesko, SL; Lewander, WJ; Linakis, JG; Woolf, AD; Wright, RO	1
Langford, JS; Sheikh, S	1
Brown, RO; Dickerson, RN; Gervasio, JM; Headley, S; Kudsk, KA; Kuhl, DA; Lima, JJ; Livingston, TN; MacLaren, R; Swift, K	1
Boivin, MA; Carey, MC; Levy, H	1
Desa, K; Protić, A; Simić, O; Sustić, A; Zelić, M; Zupan, Z	1
Empson, M; Fitzharris, P; Sood, JD; Stewart, J	1
Edwards, L	1
Bird, SB; Donovan, JL; Miller, MA; Navarro, M	1
Aarons, L; Dukes, G; Maclaren, R; Ogungbenro, K; Vasist, L; Young, M	1
Derry, S; McQuay, HJ; Moore, RA	1
Cuello, D; Fragoso, M; Salazar, G; Sergio, P; Vergez, L	1
Ehsani-Kheradgerdi, A; Grünberg, W; Mohri, M; Sharifi, K	1
Ragab, MA	1
Alshehri, MM; Alzoman, NZ; Elshahed, MS; Maher, HM; Olah, IV; Rizk, MS; Sultan, MA	1
Derry, S; Moore, RA	1
Castagné, V; Goineau, S; Guillaume, P	1
Kushwah, A; Tomar, A	1
Bundgaard, C; Christiansen, M; Griffin, BT; Henze, LJ; Holm, R; Langguth, P	1
Childress, KMS; Dothager, C; Gavard, JA; Laska, C; Lebovitz, S; Mostello, DJ	1
Johansen, SS; Linnet, K; Nielsen, MKK; Wang, X	1
Hamilton, KT; Robbins, MS	1
Micov, A; Pecikoza, U; Stepanović-Petrović, R; Tomić, M; Vuković, M	1
Abdelhamid, NS; Anwar, BH; Farid, NF; Magdy, MA; Naguib, IA	1
Fakherddine, M; Friedman, BW; Kazi, F; Manyapu, M; Mekuria, K	1

Reviews

7 review(s) available for acetaminophen and metoclopramide

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Migraine and non-steroidal anti-inflammatory agents]. Pathologie-biologie, 1992, Volume: 40, Issue:4 Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Ergotamine; Flufenamic Acid; Flurbiprofen; Humans; Metoclopramide; Migraine Disorders; Naproxen; ortho-Aminobenzoates; Randomized Controlled Trials as Topic	1992
Pharmacologic treatment of recurrent pediatric headache. Pediatric annals, 1995, Volume: 24, Issue:9 Topics: Acetaminophen; Adolescent; Adrenal Cortex Hormones; Analgesics; Aspirin; Child; Child, Preschool; Ergotamine; Humans; Methylamines; Metoclopramide; Migraine Disorders; Narcotics; Phenothiazines; Recurrence; Sumatriptan; Sympathomimetics; Vasoconstrictor Agents	1995
Paracetamol (acetaminophen) with or without an antiemetic for acute migraine headaches in adults. The Cochrane database of systematic reviews, 2010, Nov-10, Issue:11 Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Antiemetics; Drug Therapy, Combination; Humans; Hyperacusis; Metoclopramide; Migraine Disorders; Photophobia; Randomized Controlled Trials as Topic; Sumatriptan	2010
Paracetamol (acetaminophen) with or without an antiemetic for acute migraine headaches in adults. The Cochrane database of systematic reviews, 2013, Apr-30, Issue:4 Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Antiemetics; Drug Therapy, Combination; Humans; Hyperacusis; Metoclopramide; Migraine Disorders; Photophobia; Randomized Controlled Trials as Topic; Sumatriptan	2013
[Update on Current Care Guideline: Migraine]. Duodecim; laaketieteellinen aikakauskirja, 2015, Volume: 131, Issue:19 Topics: Acetaminophen; Adrenergic beta-Antagonists; Amitriptyline; Analgesics, Non-Narcotic; Analgesics, Opioid; Angiotensin II Type 1 Receptor Blockers; Anti-Inflammatory Agents, Non-Steroidal; Benzimidazoles; Biphenyl Compounds; Contraindications; Dopamine D2 Receptor Antagonists; Humans; Metoclopramide; Migraine Disorders; Practice Guidelines as Topic; Sumatriptan; Tetrazoles; Tryptamines; Vasoconstrictor Agents	2015
Second-line interventions for migraine in the emergency department: A narrative review. Headache, 2021, Volume: 61, Issue:10 Topics: Acetaminophen; Administration, Intravenous; Anti-Inflammatory Agents, Non-Steroidal; Emergency Service, Hospital; Humans; Metoclopramide; Migraine Disorders	2021

Trials

23 trial(s) available for acetaminophen and metoclopramide

Article	Year
Effect of gel fibre on gastric emptying and absorption of glucose and paracetamol. Lancet (London, England), 1979, Mar-24, Volume: 1, Issue:8117 Topics: Absorption; Acetaminophen; Adult; Blood Glucose; Cellulose; Depression, Chemical; Dietary Fiber; Female; Gastrectomy; Gastric Emptying; Gels; Glucose; Glucose Tolerance Test; Humans; Male; Metoclopramide; Pectins; Propantheline	1979
Lignocaine vs bupivacaine in prominent ear correction: a controlled trial. British journal of plastic surgery, 1992, Volume: 45, Issue:7 Topics: Acetaminophen; Adolescent; Adult; Anesthesia, General; Anesthesia, Local; Bupivacaine; Child; Child, Preschool; Double-Blind Method; Ear, External; Female; Humans; Lidocaine; Male; Metoclopramide; Morphine; Pain, Postoperative; Vomiting	1992
[Migraine and non-steroidal anti-inflammatory agents]. Pathologie-biologie, 1992, Volume: 40, Issue:4 Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Ergotamine; Flufenamic Acid; Flurbiprofen; Humans; Metoclopramide; Migraine Disorders; Naproxen; ortho-Aminobenzoates; Randomized Controlled Trials as Topic	1992
Effect of i.v. metoclopramide on gastric emptying after opioid premedication. British journal of anaesthesia, 1990, Volume: 64, Issue:4 Topics: Acetaminophen; Adolescent; Adult; Aged; Diazepam; Female; Gastric Emptying; Humans; Injections, Intramuscular; Injections, Intravenous; Male; Metoclopramide; Middle Aged; Morphine; Preanesthetic Medication	1990
Comparison of the effect of cisapride and metoclopramide on morphine-induced delay in gastric emptying. British journal of clinical pharmacology, 1988, Volume: 26, Issue:6 Topics: Acetaminophen; Adolescent; Adult; Cisapride; Clinical Trials as Topic; Double-Blind Method; Female; Gastric Emptying; Humans; Intestinal Absorption; Male; Metoclopramide; Middle Aged; Morphine; Piperidines; Premedication; Random Allocation; Time Factors	1988
[Effect of medical vagotomy on the CDDP induced nausea and vomiting evaluated by the chemotherapy-vomiting time (CV time)]. Nihon Sanka Fujinka Gakkai zasshi, 1988, Volume: 40, Issue:9 Topics: Acetaminophen; Adult; Cisplatin; Female; Humans; Metoclopramide; Middle Aged; Nausea; Ovarian Neoplasms; Random Allocation; Uterine Cervical Neoplasms; Uterine Neoplasms; Vagotomy; Vomiting	1988
The effect of metoclopramide and prochlorperazine on the absorption of effervescent paracetamol in migraine. Cephalalgia : an international journal of headache, 1988, Volume: 8, Issue:3 Topics: Acetaminophen; Administration, Rectal; Adult; Antiemetics; Female; Humans; Metoclopramide; Middle Aged; Migraine Disorders; Prochlorperazine	1988
Double-blind controlled study of paramax in the acute treatment of common and classical migraine. The British journal of clinical practice, 1985, Volume: 39, Issue:10 Topics: Acetaminophen; Adult; Aspirin; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Humans; Male; Metoclopramide; Middle Aged; Migraine Disorders	1985
Effect of metoclopramide on gastric emptying before elective and emergency caesarean section. British journal of anaesthesia, 1984, Volume: 56, Issue:10 Topics: Acetaminophen; Adult; Cesarean Section; Emergencies; Female; Gastric Emptying; Humans; Labor, Obstetric; Metoclopramide; Narcotics; Pregnancy; Time Factors	1984
Paracetamol plus metoclopramide ('Paramax') as an adjunct analgesic in the treatment of arthritis. Current medical research and opinion, 1983, Volume: 8, Issue:8 Topics: Acetaminophen; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Drug Combinations; Humans; Metoclopramide; Osteoarthritis; Pain; Random Allocation; Time Factors	1983
Chlormezanone in the treatment of migraine attacks: a double blind comparison with diazepam and placebo. Cephalalgia : an international journal of headache, 1982, Volume: 2, Issue:4 Topics: Acetaminophen; Chlormezanone; Clinical Trials as Topic; Diazepam; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Metoclopramide; Migraine Disorders; Random Allocation	1982
Paracetamol absorption from Paramax, Panadol and Solpadeine. British journal of clinical pharmacology, 1983, Volume: 15, Issue:4 Topics: Acetaminophen; Administration, Oral; Adult; Caffeine; Codeine; Drug Combinations; Humans; Male; Metoclopramide	1983
Prophylactic antiemetic treatment with ondansetron in children undergoing tonsillectomy. Anesthesiology, 1994, Volume: 81, Issue:4 Topics: Acetaminophen; Antiemetics; Child; Child, Preschool; Double-Blind Method; Droperidol; Female; Humans; Incidence; Injections, Intravenous; Male; Meperidine; Metoclopramide; Nausea; Nitrous Oxide; Ondansetron; Oxygen; Pain; Postoperative Complications; Tonsillectomy; Vomiting	1994
Effects of enhancement and antagonism of 5-hydroxytryptamine activity on the influence of metoclopramide on gastric emptying. Digestion, 1993, Volume: 54, Issue:1 Topics: Acetaminophen; Adult; Fluoxetine; Gastric Emptying; Humans; Male; Metergoline; Methysergide; Metoclopramide; Pizotyline; Premedication; Receptors, Serotonin; Serotonin; Single-Blind Method; Time Factors	1993
The proportional cumulative area under the curve of paracetamol used as an index of gastric emptying in diabetic patients with symptoms of gastroparesis. Clinical and experimental pharmacology & physiology, 1995, Volume: 22, Issue:9 Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Dopamine Antagonists; Female; Gastric Emptying; Gastroparesis; Humans; Male; Metoclopramide; Middle Aged	1995
The novel anti-migraine compound zolmitriptan (Zomig 311C90) has no clinically significant interactions with paracetamol or metoclopramide. European journal of clinical pharmacology, 1997, Volume: 53, Issue:3-4 Topics: Acetaminophen; Adult; Blood Pressure; Drug Interactions; Female; Humans; Male; Metoclopramide; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines	1997
Effect of metoclopramide dose on preventing emesis after oral administration of N-acetylcysteine for acetaminophen overdose. Journal of toxicology. Clinical toxicology, 1999, Volume: 37, Issue:1 Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Analgesics, Non-Narcotic; Antidotes; Antiemetics; Child; Child, Preschool; Drug Overdose; Female; Humans; Male; Metoclopramide; Middle Aged; Prospective Studies; Regression Analysis	1999
Sequential single doses of cisapride, erythromycin, and metoclopramide in critically ill patients intolerant to enteral nutrition: a randomized, placebo-controlled, crossover study. Critical care medicine, 2000, Volume: 28, Issue:2 Topics: Acetaminophen; Administration, Oral; Adult; Aged; Antiemetics; Cisapride; Critical Illness; Cross-Over Studies; Enteral Nutrition; Erythromycin; Female; Gastric Emptying; Gastrointestinal Agents; Humans; Intestinal Absorption; Male; Metoclopramide; Middle Aged; Placebos; Respiration, Artificial; Time Factors	2000
Erythromycin accelerates gastric emptying in a dose-response manner in healthy subjects. Pharmacotherapy, 2003, Volume: 23, Issue:1 Topics: Acetaminophen; Adolescent; Adult; Aged; Cross-Over Studies; Dopamine Antagonists; Dose-Response Relationship, Drug; Erythromycin; Female; Gastric Emptying; Humans; Male; Metoclopramide; Middle Aged; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide	2003
Metoclopramide improves gastric but not gallbladder emptying in cardiac surgery patients with early intragastric enteral feeding: randomized controlled trial. Croatian medical journal, 2005, Volume: 46, Issue:2 Topics: Acetaminophen; Aged; Coronary Artery Bypass; Dopamine Antagonists; Double-Blind Method; Drug Combinations; Enteral Nutrition; Female; Gallbladder; Gastric Emptying; Humans; Intensive Care Units; Male; Metoclopramide; Middle Aged; Placebos; Prospective Studies; Time Factors	2005
Metoclopramide as an analgesic in severe migraine attacks: an open, single-blind, parallel control study. Recent patents on CNS drug discovery, 2011, May-01, Volume: 6, Issue:2 Topics: Acetaminophen; Adult; Analgesics; Female; Humans; Male; Metoclopramide; Migraine Disorders; Single-Blind Method	2011
Clinicopharmacological comparative study of rizatriptan versus conventional therapy in migraine. Journal of the Indian Medical Association, 2014, Volume: 112, Issue:1 Topics: Acetaminophen; Adolescent; Adult; Aged; Alprazolam; Analgesics, Non-Narcotic; Female; Flunarizine; Humans; Male; Metoclopramide; Middle Aged; Migraine Disorders; Prospective Studies; Serotonin Receptor Agonists; Treatment Outcome; Triazoles; Tryptamines; Vasodilator Agents; Young Adult	2014
Metoclopramide and Diphenhydramine: A Randomized Controlled Trial of a Treatment for Headache in Pregnancy when Acetaminophen Alone Is Ineffective (MAD Headache Study). American journal of perinatology, 2018, Volume: 35, Issue:13 Topics: Acetaminophen; Adult; Analgesics; Antiemetics; Codeine; Diphenhydramine; Double-Blind Method; Drug Administration Routes; Drug Resistance; Drug Therapy, Combination; Female; Headache; Humans; Metoclopramide; Pain Measurement; Pregnancy; Pregnancy Complications; Treatment Outcome	2018

Other Studies

52 other study(ies) available for acetaminophen and metoclopramide

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Narcotic analgesics and delayed gastric emptying during labour. Lancet (London, England), 1975, Apr-19, Volume: 1, Issue:7912 Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Analgesics, Opioid; Anesthesia, Obstetrical; Female; Gastrointestinal Motility; Heroin; Humans; Intestinal Absorption; Labor, Obstetric; Meperidine; Metoclopramide; Pentazocine; Postpartum Period; Pregnancy; Stomach; Time Factors	1975
[Experience with 750 migraine patients at a headache clinic]. Ugeskrift for laeger, 1979, Sep-03, Volume: 141, Issue:36 Topics: Acetaminophen; Adult; Aged; Aspirin; Diazepam; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Male; Metoclopramide; Middle Aged; Migraine Disorders; Morphine Derivatives	1979
Influence of cisapride, metoclopramide and loperamide on gastric emptying of normal volunteers as measured by means of the area under the curve of the cumulative fraction absorbed-time profiles of paracetamol. Methods and findings in experimental and clinical pharmacology, 1992, Volume: 14, Issue:5 Topics: Acetaminophen; Adult; Biological Availability; Cisapride; Gastric Emptying; Humans; Loperamide; Male; Metoclopramide; Piperidines; Serotonin Antagonists	1992
[Pharmacokinetic aspects of a combination of metoclopramide and paracetamol. Results of a human kinetic study and consequences for migraine patients]. Arzneimittel-Forschung, 1992, Volume: 42, Issue:4 Topics: Acetaminophen; Adult; Biological Availability; Drug Combinations; Female; Half-Life; Humans; Male; Metoclopramide; Migraine Disorders	1992
Stimulatory effect of N-[4-[2-(dimethylamino)-ethoxy] benzyl]-3,4-dimethoxybenzamide hydrochloride (HSR-803) on normal and delayed gastrointestinal propulsion. Japanese journal of pharmacology, 1991, Volume: 56, Issue:3 Topics: Acetaminophen; Administration, Oral; Animals; Benzamides; Benzyl Compounds; Cisapride; Dogs; Domperidone; Dopamine; Dyspepsia; Female; Gastric Emptying; Gastrointestinal Motility; Male; Metoclopramide; Mice; Piperidines; Rats; Rats, Inbred Strains; Stimulation, Chemical	1991
The mean cumulative fraction absorbed-time profiles of paracetamol as an index of gastric emptying. Methods and findings in experimental and clinical pharmacology, 1990, Volume: 12, Issue:4 Topics: Acetaminophen; Adult; Atropine; Biological Availability; Gastric Emptying; Humans; Intestinal Absorption; Male; Metoclopramide; Neostigmine; Pirenzepine	1990
The influence of gastric emptying on droxicam pharmacokinetics. Journal of clinical pharmacology, 1989, Volume: 29, Issue:8 Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Chromatography, High Pressure Liquid; Ethics, Medical; Gastric Emptying; Humans; Male; Metoclopramide; Piroxicam; Propantheline; Pyridines	1989
Treatment of common minor ailments. British medical journal (Clinical research ed.), 1986, Dec-13, Volume: 293, Issue:6561 Topics: Acetaminophen; Antacids; Antiemetics; Aspirin; Dyspepsia; Female; Heartburn; Histamine H1 Antagonists; Humans; Metoclopramide; Nausea; Pregnancy; Pregnancy Complications; Vomiting	1986
Migraine--treatment of acute attack. Scottish medical journal, 1985, Volume: 30, Issue:4 Topics: Acetaminophen; Acute Disease; Aspirin; Caffeine; Ergotamine; Ergotamines; Humans; Metoclopramide; Migraine Disorders; Sleep; Time Factors	1985
The influence of metoclopramide on drug absorption. Postgraduate medical journal, 1973, Volume: 49 Suppl 4 Topics: Acetaminophen; Administration, Oral; Aged; Female; Gastrointestinal Motility; Humans; Injections, Intravenous; Intestinal Absorption; Metoclopramide; Propantheline; Tetracycline	1973
Strained abdominal muscles as a cause of acute abdominal pain in children and young adults and its treatment with Paramax. The British journal of clinical practice, 1983, Volume: 37, Issue:5 Topics: Abdomen; Abdominal Muscles; Acetaminophen; Adolescent; Adult; Child; Drug Combinations; Female; Humans; Male; Metoclopramide; Pain; Sprains and Strains	1983
Treatment of the acute migraine attack--current status. Cephalalgia : an international journal of headache, 1983, Volume: 3, Issue:1 Topics: Acetaminophen; Aspirin; Drug Therapy, Combination; Ergotamine; Ergotamines; Humans; Metoclopramide; Migraine Disorders	1983
Paracetamol absorption from Paramax, Panadol and Solpadeine. British journal of clinical pharmacology, 1983, Volume: 16, Issue:5 Topics: Absorption; Acetaminophen; Caffeine; Codeine; Drug Combinations; Humans; Metoclopramide	1983
A plain man's guide to the management of migraine. British medical journal (Clinical research ed.), 1982, Apr-10, Volume: 284, Issue:6322 Topics: Acetaminophen; Aspirin; Ergotamine; Headache; Humans; Metoclopramide; Migraine Disorders; Sleep	1982
Migraine: a rational approach to therapy. The British journal of clinical practice, 1982, Volume: 36, Issue:10 Topics: Acetaminophen; Adolescent; Adult; Aged; Child; Drug Combinations; Female; Humans; Male; Metoclopramide; Middle Aged; Migraine Disorders	1982
A double blind study of metoclopramide in the treatment of migraine attacks. Journal of neurology, neurosurgery, and psychiatry, 1980, Volume: 43, Issue:4 Topics: Acetaminophen; Adolescent; Adult; Aged; Diazepam; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Metoclopramide; Middle Aged; Migraine Disorders; Nausea	1980
Paracetamol (acetaminophen) versus acetylsalicylic acid in migraine. European neurology, 1980, Volume: 19, Issue:3 Topics: Acetaminophen; Acute Disease; Aspirin; Diazepam; Drug Evaluation; Drug Therapy, Combination; Humans; Metoclopramide; Migraine Disorders	1980
Study of migraine and the treatment of acute attacks in industry. The Journal of international medical research, 1980, Volume: 8, Issue:5 Topics: Absenteeism; Acetaminophen; Adolescent; Adult; England; Female; Humans; Male; Metoclopramide; Middle Aged; Migraine Disorders; Occupational Medicine; Rest	1980
[Paracetamol and metoclopramide in fixed combination?]. Medizinische Monatsschrift fur Pharmazeuten, 1996, Volume: 19, Issue:4 Topics: Acetaminophen; Analgesics, Non-Narcotic; Antiemetics; Drug Combinations; Humans; Metoclopramide; Migraine Disorders	1996
In vitro drug adsorption to charcoal, silicas, acrylate copolymer and silicone oil with charcoal and with acrylate copolymer. Human & experimental toxicology, 1997, Volume: 16, Issue:1 Topics: Acetaminophen; Acrylates; Adsorption; Antipyrine; Binding Sites; Charcoal; Metoclopramide; Pharmaceutical Preparations; Silicon Dioxide; Silicone Oils; Warfarin	1997
Acetaminophen as a marker of gastric emptying in ponies. Equine veterinary journal, 1998, Volume: 30, Issue:4 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Bacterial Agents; Antiemetics; Area Under Curve; Atropine; Erythromycin; Gastric Emptying; Horses; Metoclopramide; Parasympatholytics; Sympatholytics; Yohimbine	1998
Metoclopramide ameliorates the effects of endotoxin on gastric emptying of acetaminophen in horses. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 1999, Volume: 63, Issue:1 Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Biomarkers; Dopamine Antagonists; Endotoxins; Female; Gastric Emptying; Horses; Metoclopramide	1999
An adolescent case of sulfhemoglobinemia associated with high-dose metoclopramide and N-acetylcysteine. Annals of emergency medicine, 1999, Volume: 34, Issue:4 Pt 1 Topics: Acetaminophen; Acetylcysteine; Adolescent; Antiemetics; Female; Humans; Metoclopramide; Poisoning; Sulfhemoglobinemia	1999
Too much of a good thing, is it bad? Adrenaline on trial. The New Zealand medical journal, 2007, Apr-13, Volume: 120, Issue:1252 Topics: Acetaminophen; Adult; Angioedema; Arrhythmias, Cardiac; Dose-Response Relationship, Drug; Drug Combinations; Drug Hypersensitivity; Epinephrine; Humans; Injections, Intravenous; Injections, Subcutaneous; Male; Medication Errors; Metoclopramide; Pulmonary Edema; Tongue Diseases; Treatment Outcome; Ventricular Dysfunction, Left	2007
Hyperprolactinaemia in a patient with cystic fibrosis. British journal of hospital medicine (London, England : 2005), 2007, Volume: 68, Issue:8 Topics: Acetaminophen; Analgesics, Non-Narcotic; Antiemetics; Cystic Fibrosis; Domperidone; Drug Combinations; Female; Galactorrhea; Gastrointestinal Agents; Humans; Hyperprolactinemia; Metoclopramide	2007
Antiemetic use in acetaminophen poisoning: how does the route of N-acetylcysteine administration affect utilization? Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2007, Volume: 3, Issue:4 Topics: Acetaminophen; Acetylcysteine; Administration, Oral; Adult; Analgesics, Non-Narcotic; Antidotes; Antiemetics; Cost-Benefit Analysis; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Male; Metoclopramide; Ondansetron; Poisoning; Retrospective Studies; Treatment Outcome	2007
A semi-mechanistic gastric emptying model for the population pharmacokinetic analysis of orally administered acetaminophen in critically ill patients. Pharmaceutical research, 2011, Volume: 28, Issue:2 Topics: Acetaminophen; Administration, Oral; Algorithms; Analgesics, Non-Narcotic; Antiemetics; Critical Illness; Enteral Nutrition; Erythromycin; Follow-Up Studies; Gastric Emptying; Gastrointestinal Agents; Humans; Metoclopramide; Models, Biological; Time Factors	2011
Evaluation of a modified acetaminophen absorption test to estimate the abomasal emptying rate in Holstein-Friesian heifers. American journal of veterinary research, 2011, Volume: 72, Issue:12 Topics: Abomasum; Absorption; Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Area Under Curve; Atropine; Cattle; Cross-Over Studies; Female; Gastric Emptying; Infusions, Intravenous; Infusions, Subcutaneous; Intestinal Absorption; Metoclopramide; Parasympatholytics; Veterinary Medicine	2011
Effect of metoclopramide on the excretion rate of paracetamol using HPLC-DAD. Journal of chromatographic science, 2013, Volume: 51, Issue:4 Topics: Acetaminophen; Chromatography, High Pressure Liquid; Drug Interactions; Drug Stability; Humans; Linear Models; Male; Metoclopramide; Pharmacokinetics; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction	2013
Capillary electrophoretic determination of antimigraine formulations containing caffeine, ergotamine, paracetamol and domperidone or metoclopramide. Journal of chromatographic science, 2013, Volume: 51, Issue:6 Topics: Acetaminophen; Caffeine; Domperidone; Drug Combinations; Drug Stability; Electrophoresis, Capillary; Ergotamine; Hydrogen-Ion Concentration; Limit of Detection; Linear Models; Metoclopramide; Migraine Disorders; Osmolar Concentration; Reproducibility of Results; Tablets; Tartrates; Temperature	2013
Comparison of the effects of clonidine, loperamide and metoclopramide in two models of gastric emptying in the rat. Fundamental & clinical pharmacology, 2015, Volume: 29, Issue:1 Topics: Acetaminophen; Animals; Clonidine; Gastric Emptying; Gastric Mucosa; Intestine, Small; Loperamide; Male; Metoclopramide; Phenolsulfonphthalein; Rats; Rats, Wistar	2015
Exploring gastric emptying rate in minipigs: Effect of food type and pre-dosing of metoclopramide. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2018, Jun-15, Volume: 118 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Antiemetics; Dopamine D2 Receptor Antagonists; Drug Interactions; Fasting; Female; Food; Gastric Emptying; Metoclopramide; Swine; Swine, Miniature	2018
Segmental Hair Analysis-Interpretation of the Time of Drug Intake in Two Patients Undergoing Drug Treatment. Journal of forensic sciences, 2019, Volume: 64, Issue:3 Topics: Acetaminophen; Adult; Analgesics; Antiemetics; Azabicyclo Compounds; Citalopram; Female; Forensic Toxicology; Hair; Humans; Hypnotics and Sedatives; Metoclopramide; Morphine; Oxazepam; Piperazines; Selective Serotonin Reuptake Inhibitors; Sertraline; Sumatriptan; Tramadol; Vasoconstrictor Agents	2019
Migraine Treatment in Pregnant Women Presenting to Acute Care: A Retrospective Observational Study. Headache, 2019, Volume: 59, Issue:2 Topics: Acetaminophen; Adult; Analgesics; Antiemetics; Diphenhydramine; Drug Therapy, Combination; Female; Humans; Metoclopramide; Migraine Disorders; Pregnancy; Pregnancy Complications; Retrospective Studies; Treatment Outcome; Young Adult	2019
Eslicarbazepine acetate interacts in a beneficial manner with standard and alternative analgesics to reduce trigeminal nociception. Psychopharmacology, 2020, Volume: 237, Issue:5 Topics: Acetaminophen; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Dibenzazepines; Male; Metoclopramide; Mice; Nociception; Pain; Pain Measurement; Rats, Sprague-Dawley; Stress, Psychological; Trigeminal Nerve Diseases	2020
Validated ecofriendly chromatographic method for quantitative determination of anti-migraine quaternary mixture. Journal of separation science, 2020, Volume: 43, Issue:12 Topics: Acetaminophen; Caffeine; Chromatography, Thin Layer; Drug Compounding; Ergotamine; Metoclopramide; Molecular Structure	2020