acetaminophen has been researched along with metallothionein in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (37.50) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (37.50) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Piotrowski, JK; Swietlicka, EA; Szymańska, JA | 1 |
| Benson, RW; Hinson, JA; Potter, DW; Pumford, NR; Roberts, DW | 1 |
| Waalkes, MP; Ward, JM | 1 |
| Chengelis, CP; Dodd, DC; Kotsonis, FN; Means, JR | 1 |
| Calp, D; Wormser, U | 1 |
| Atkins, LM; Fody, EP; Gale, GR; Smith, AB; Walker, EM | 1 |
| Bracken, WM; Dudley, RE; Goering, PL; Hazelton, GA; Hjelle, JJ; Klaassen, CD | 1 |
| Barry, EF; Coyle, P; Philcox, JC; Rofe, AM; Shelton, TL | 1 |
| Cohen, SD; Hartley, D; Klaassen, CD; Liu, J; Liu, Y; Lucas, A; Shehin-Johnson, SE | 1 |
| Artigues, A; Farhood, A; Jaeschke, H; Saito, C; Villar, MT; Yan, HM | 1 |
| Cai, DJ; Jin, T; Klaassen, CD; Liu, J; Lu, Y; Wu, Q; Xu, YQ; Zhang, D | 1 |
| Hu, Z; Lv, Y; Wang, F; Xing, G; Zhang, B | 1 |
| Bajt, ML; Jaeschke, H; Lebofsky, M; McGill, MR; Williams, CD | 1 |
| Jin, T; Liu, J; Shi, JS; Tao, N; Wu, Q; Zhang, D; Zhu, QN | 1 |
| Kanno, S; Tomizawa, A; Yomogida, S | 1 |
| Devisscher, L; Geerts, A; Hoorens, A; Laukens, D; Lefere, S; Lynes, MA; Raevens, S; Tilleman, L; Van Campenhout, S; Van Eeckhoutte, HP; Van Nieuwerburgh, F; Van Vlierberghe, H | 1 |
16 other study(ies) available for acetaminophen and metallothionein
| Article | Year |
|---|---|
Protective effect of zinc in the hepatotoxicity of bromobenzene and acetaminophen.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Bromobenzenes; Glutathione; Injections, Intraperitoneal; L-Iditol 2-Dehydrogenase; Liver; Male; Metallothionein; Mice; Mice, Inbred BALB C; Zinc | 1991 |
Epitope characterization of acetaminophen bound to protein and nonprotein sulfhydryl groups by an enzyme-linked immunosorbent assay.
Topics: Acetaminophen; Animals; Enzyme-Linked Immunosorbent Assay; Epitopes; Metallothionein; Protein Binding; Rabbits; Structure-Activity Relationship; Sulfhydryl Compounds | 1989 |
Induction of hepatic metallothionein in male B6C3F1 mice exposed to hepatic tumor promoters: effects of phenobarbital, acetaminophen, sodium barbital, and di(2-ethylhexyl) phthalate.
Topics: Acetaminophen; Animals; Barbital; Cadmium; Carcinogens; Chromatography, Gel; Cytosol; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Liver; Male; Metallothionein; Mice; Phenobarbital; Phthalic Acids; Zinc | 1989 |
Protection by zinc against acetaminophen induced hepatotoxicity in mice.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Glucuronosyltransferase; Glutathione; Liver; Male; Metallothionein; Mice; Mice, Inbred ICR; Subcellular Fractions; Time Factors; Zinc | 1986 |
Increased levels of hepatic metallothionein in rat and mouse after injection of acetaminophen.
Topics: Acetaminophen; Animals; Chromatography, Gel; Dose-Response Relationship, Drug; Liver; Male; Metallothionein; Mice; Rats; Rats, Inbred Strains | 1988 |
Effects of acetaminophen on cadmium metabolism in mice.
Topics: Acetaminophen; Animals; Body Burden; Cadmium; Chromatography, Gel; Cysteine; Feces; Kidney; Liver; Male; Metallothionein; Mice; Phenobarbital | 1986 |
Role of sulfhydryls in the hepatotoxicity of organic and metallic compounds.
Topics: Acetaminophen; Animals; Biotransformation; Bromobenzenes; Cadmium Poisoning; Chemical and Drug Induced Liver Injury; Cysteine; Cytochrome P-450 Enzyme System; Humans; Metallothionein; Metals; Microsomes, Liver; Sulfhydryl Compounds; Zinc | 1985 |
Paracetamol hepatotoxicity in metallothionein-null mice.
Topics: Acetaminophen; Alanine Transaminase; Animals; Cells, Cultured; Fasting; Female; L-Lactate Dehydrogenase; Liver; Male; Metallothionein; Mice; Mice, Inbred C57BL; Mice, Inbred Strains | 1998 |
Metallothionein-I/II knockout mice are sensitive to acetaminophen-induced hepatotoxicity.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Glutathione; Lipid Peroxidation; Liver; Metallothionein; Mice; Mice, Knockout; Oxidative Stress | 1999 |
Mechanism of protection by metallothionein against acetaminophen hepatotoxicity.
Topics: Acetaminophen; Animals; Blotting, Western; Immunohistochemistry; Liver; Male; Metallothionein; Mice; Mice, Inbred C57BL; Oxidative Stress; Spectrometry, Mass, Electrospray Ionization | 2010 |
Diurnal variation of hepatic antioxidant gene expression in mice.
Topics: Acetaminophen; Aging; Animals; Antioxidants; Circadian Rhythm; CLOCK Proteins; Female; Gene Expression Regulation; Glutathione; Liver; Liver Diseases; Male; Metallothionein; Mice; NF-E2-Related Factor 2; RNA, Messenger | 2012 |
Protective effect of naringenin against acetaminophen-induced acute liver injury in metallothionein (MT)-null mice.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Flavanones; Glutathione; Humans; Liver; Male; Malondialdehyde; Metallothionein; Mice; Mice, Knockout; Protective Agents | 2013 |
Protection against acetaminophen-induced liver injury by allopurinol is dependent on aldehyde oxidase-mediated liver preconditioning.
Topics: Acetaminophen; Aldehyde Oxidase; Allopurinol; Animals; Chemical and Drug Induced Liver Injury; Cysteine; Drug Overdose; Glutathione; JNK Mitogen-Activated Protein Kinases; Liver; Male; Metallothionein; Mice; Mice, Inbred C3H; Mitochondria; Oxypurinol; Phosphorylation; Xanthine Oxidase | 2014 |
Induction of Nrf2 and metallothionein as a common mechanism of hepatoprotective medicinal herbs.
Topics: Acetaminophen; Animals; Antioxidants; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Galactosamine; Glutamate-Cysteine Ligase; Heme Oxygenase-1; Liver; Male; Metallothionein; Mice; Mice, Inbred Strains; Molecular Targeted Therapy; NAD(P)H Dehydrogenase (Quinone); NADP; NF-E2-Related Factor 2; Oxidative Stress; Phytotherapy; Piper; Plant Extracts | 2014 |
Detecting mRNA Predictors of Acetaminophen-Induced Hepatotoxicity in Mouse Blood Using Quantitative Real-Time PCR.
Topics: Acetaminophen; Alanine Transaminase; Analgesics; Animals; Antipyretics; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Glutathione Peroxidase; Interleukin-10; Interleukin-1beta; Male; Metallothionein; Mice; Prealbumin; Real-Time Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha | 2016 |
Metallothioneins alter macrophage phenotype and represent novel therapeutic targets for acetaminophen-induced liver injury.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Antibodies, Monoclonal; Chemical and Drug Induced Liver Injury; Humans; Macrophages; Male; Metallothionein; Mice; Mice, Inbred C57BL | 2022 |