acetaminophen has been researched along with malondialdehyde in 148 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (2.70) | 18.7374 |
| 1990's | 16 (10.81) | 18.2507 |
| 2000's | 26 (17.57) | 29.6817 |
| 2010's | 85 (57.43) | 24.3611 |
| 2020's | 17 (11.49) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, TJ | 1 |
| Altorjay, I; Balla, G; Dalmi, L; Imre, S; Sári, B | 1 |
| Ding, Y; Huang, DK; Shen, JP; Zhang, XL; Zhang, YD; Zhu, SH | 1 |
| Piotrowski, JK; Skrzypińska-Gawrysiak, M; Sporny, S; Swietlicka, EA; Szymańska, JA | 1 |
| Cao, Z; Cheng, T; Duan, Z; Li, T; Ma, Z; Zhang, P | 1 |
| Lemoine, R; Sause, C; Siegers, CP; Younes, M | 1 |
| Fischer, LJ; Harman, AW | 1 |
| Albano, E; Biasi, F; Chiarpotto, E; Dianzani, MU; Poli, G | 1 |
| Duniec, Z; Kostka-Trabka, E; Robak, J | 1 |
| Cheng, TJ; Qin, H; Zhang, PY | 1 |
| Peng, RX; Wang, H | 1 |
| Harding, JJ; Riley, ML | 1 |
| Cho, CH; Kaan, SK; Woo, PC | 1 |
| Altomare, E; Grattagliano, I; Guerrieri, F; Turturro, N; Vendemiale, G | 1 |
| Kim, SN; Kim, YC; Yoon, MY | 1 |
| Rommelspacher, H; Włodek, L | 1 |
| Choi, BH; Oak, S | 1 |
| Li, JY; Sun, H; Yu, JR | 1 |
| Ahn, BO; Kim, SH; Kim, WB; Lee, EB; Oh, TY; Ryu, BK | 1 |
| Ishikawa, M; Kanno, S; Sasaki, K; Takayanagi, M; Takayanagi, Y | 1 |
| Birmingham, JM; Bugelski, PJ; Elcock, F; Greenhill, RW; O'Brien, PJ; Slaughter, MR; Swain, A | 1 |
| Ahmed, MB; Khater, MR | 1 |
| Cho, CC; Cho, CH; Lee, SS; Li, Y; Liu, ES; Sheng, HP; So, HL; Ye, YN | 1 |
| Di Massa, A; Frangov, P; Galunska, B; Krushkov, I; Marazova, K; Popov, A; Tankova, T | 1 |
| Cheng, GF; Hou, YN; Liang, XL; Zhu, XY | 1 |
| Al-Bekairi, AM; Al-Shabanah, OA; Gamal el-din, AM; Mostafa, AM; Nagi, MN | 1 |
| Boulkour, S; Fillastre, JP; Lahouel, M; Segueni, N | 1 |
| Hsu, CC; Liao, TS; Lin, CC; Yin, MC | 1 |
| Küpeli, E; Orhan, DD; Yesilada, E | 1 |
| Ercan, F; Gedik, N; Omurtag, GZ; Sehirli, O; Sener, G; Tozan, A; Yüksel, M | 1 |
| Cetinel, S; Sehirli, AO; Sener, G; Toklu, HZ; Velioğlu-Oğünç, A | 1 |
| Lin, CC; Lin, LT; Wu, TH; Yen, FL | 1 |
| Demopoulos, CA; Grypioti, AD; Kostopanagiotou, G; Mykoniatis, M | 1 |
| Grypioti, AD; Kostopanagiotou, G; Mykoniatis, M | 1 |
| Atakisi, O; Citil, M; Erginsoy, S; Karapehlivan, M; Kart, A; Tunca, R; Yapar, K | 1 |
| Cham, TM; Lin, CC; Lin, LT; Wu, TH; Yen, FL | 1 |
| Bhadauria, M; Nirala, SK | 1 |
| Hsu, CC; Lin, KY; Lin, WL; Wang, ZH; Yin, MC | 1 |
| Arafa, HM | 1 |
| Duru, M; Helvaci, R; Kaya, H; Koc, A; Kozlu, T; Kuvandik, G; Nacar, A; Sogüt, S; Yonden, Z | 1 |
| Han, XH; Nan, JX; Piao, DM; Wu, YL | 1 |
| Adiguzel, K; Akgoz, M; Cigremis, Y; Karaman, M; Kart, A; Ozen, H; Turel, H | 1 |
| Jesić-Vukićević, R; Mladenović, D; Ninković, M; Radosavljević, T; Todorović, V; Vucević, D | 1 |
| Choi, CY; Choi, JH; Chung, YC; Hwang, YP; Jeong, HG; Lee, KJ | 1 |
| Jin, GZ; Piao, GC; Yuan, HD | 1 |
| Jiang, YZ; Jin, HR; Jin, XJ; Joon Lee, J; Lian, LH; Nan, JX; Piao, JY; Wan, Y; Wu, YL | 1 |
| Dehpour, AR; Javidnia, K; Kheradpezhouh, E; Miri, R; Monabati, A; Noorafshan, A; Panjehshahin, MR | 1 |
| Manimaran, A; Sankar, P; Sarkar, SN | 1 |
| Jiang, YZ; Lian, LH; Nan, JX; Wang, AY; Wu, YL | 1 |
| Egashira, Y; Lu, J; Ren, DF; Sanada, H; Wang, JZ | 1 |
| Briyal, S; Gulati, A | 1 |
| Acharya, M; Lau-Cam, CA | 2 |
| Abdelwahab, SA; Elbitar, HI; Ibrahim, SA; Morsy, MA; Zedan, MZ | 1 |
| Chandrasekaran, VR; Chien, SP; Hsu, DZ; Liu, MY | 1 |
| Cervinková, Z; Haňáčková, L; Kučera, O; Lotková, H; Podhola, M; Roušar, T; Staňková, P | 1 |
| He, YY; Jia, FL; Zhang, BX | 1 |
| Fouad, AA; Jresat, I | 1 |
| Abdul Hamid, Z; Budin, SB; Hamid, A; Husain, K; Mohamed, J; Wen Jie, N | 1 |
| Hewawasam, RP; Jayatilaka, KA; Pathirana, C | 1 |
| Akgul, EO; Cakir, E; Cayci, T; Demirbag, S; Eyi, YE; Gul, H; Kaldirim, U; Korkmaz, A; Macit, E; Oter, S; Ozler, M; Oztas, E; Topal, T; Toygar, M; Uysal, B; Yaman, H; Yildirim, AO | 1 |
| Armagan, G; Kanit, L; Yalcin, A | 1 |
| He, YY; Jia, FL; Liu, WX; Zhang, BX | 1 |
| Arulselvan, P; Fakurazi, S; Sharifudin, SA | 1 |
| Krasteva, I; Mitcheva, M; Nikolov, S; Simeonova, R; Vitcheva, V | 1 |
| Al-Mulhim, AS; Fouad, AA; Gomaa, W; Jresat, I | 1 |
| Agha, AM; Galal, RM; Seif El-Nasr, MM; Zaki, HF | 1 |
| Hu, Z; Lv, Y; Wang, F; Xing, G; Zhang, B | 1 |
| Athira, S; Kumar, R; Mann, B; Sharma, R | 1 |
| Bayir, Y; Cadirci, E; Demirci, E; Ferah, I; Halici, Z; Unal, B | 1 |
| Choi, J; Jang, SI; Kim, SZ; Park, KH; Shin, JH | 1 |
| Klaikeaw, N; Somanawat, K; Thong-Ngam, D | 1 |
| Gu, ZL; Wang, XY; Xie, ML; Xue, J; Yang, J | 1 |
| Ji, B; Tian, W; Wang, R; Wang, Y; Wu, W; Yang, Z; Zhang, D | 1 |
| Mandal, A; Mandal, S; Mondal, KCh; Nandi, DK; Paul, T; Pradhan, S; Roy, S | 1 |
| Abdel-Azeem, AS; El-Sayed, EM; Farrag, AR; Hegazy, AM; Ibrahim, KS | 1 |
| El-Agamy, DS; Gamil, NM; Makled, MN | 1 |
| Chen, JB; Chen, XM; Gong, Q; Li, G; Nie, H; Qin, XY; Wang, C; Xu, Z | 1 |
| Heidarian, E; Jafari-Dehkordi, E; Saffari, J | 1 |
| Barakat, W; El-Moselhy, MA; Elshazly, SM | 1 |
| Li, W; Pu, XP; Sun, H; Sun, Y; Wang, YH; Yang, YF; Zhao, X; Zheng, XY | 1 |
| Baki, E; Coşkun, I; Eroglu, A; Karahan, SC; Kerimoğlu, S; Koşucu, M; Kutanis, D; Menteşe, A; Topbas, M | 1 |
| Das, K; Mahapatra, SD; Mahapatra, TD; Mandal, A; Mandal, S; Mondal, KC; Nandi, DK; Patra, A; Paul, T; Roy, S | 1 |
| Antunes, SC; Correia, AT; Gonçalves, F; Nunes, B; Ramos, AS | 1 |
| Antunes, SC; Gonçalves, F; Martins, L; Nunes, B; Pinto, G | 1 |
| Klaikeaw, N; Linlawan, S; Rerknimitr, R; Siriviriyakul, P; Somanawat, K; Thanapirom, K; Werawatganon, D | 1 |
| Azmy, RM; Naguib, YM; Salem, MF; Samaka, RM | 1 |
| Adetuyi, AO; Akindahunsi, AA; Akinmoladun, AC; Komolafe, K; Olaleye, MT | 1 |
| Bhattacharjee, C; Chowdhury, R; Kunjiappan, S | 1 |
| Cao, W; Cheng, N; Gao, H; Li, D; Sun, L; Wang, Y; Xue, X | 1 |
| Dağlı, B; Demirci, B; Gökçimen, A; Kahyaoğlu, F; Ömürlü, İK; Uysal, HB; Yılmaz, M | 1 |
| Abiko, Y; Hagiya, Y; Ishii, I; Kamata, S; Kasahara, T; Kumagai, Y | 1 |
| Aksu, EH; Çomaklı, S; Eldutar, E; Kandemir, FM; Küçükler, S; Ömür, AD; Özkaraca, M | 1 |
| Atmaca, HT; Bayir, Y; Canayakin, D; Halici, Z; Keles, MS; Kilic Baygutalp, N; Kocak Ozgeris, FB; Sezen Karaoglan, E | 1 |
| Adil, M; Bodhankar, SL; Ghosh, P; Kandhare, AD; Raygude, KS; Venkata, S | 1 |
| Boonruamkaew, P; Chonpathompikunlert, P; Nagasaki, Y | 1 |
| Chen, Y; Deng, Y; Ding, Y; Li, Q; Qian, K; Xu, Y; Zhi, F | 1 |
| Chou, AH; Day, YJ; Lee, HC; Liao, CC; Liou, JT; Liu, FC | 1 |
| Abdelzaher, WY; Kamel, MY; Rofaeil, RR | 1 |
| Huang, W; Jin, F; Li, W; Peng, D; Wan, C; Yao, L; Zhao, H; Zou, Y | 1 |
| Chu, L; Chu, X; Han, X; Song, Q; Zhang, F; Zhang, J; Zhang, X; Zhang, Y | 1 |
| He, YF; Hou, W; Hu, JN; Li, W; Liu, Z; Wang, ZQ; Xu, XY; Yang, G; Zhang, R | 1 |
| Dai, J; Ge, P; Gong, X; Lin, L; Xing, Y; Yang, C; Yi, J; Zhang, L | 1 |
| Abdelrahem, MT; Azim, SAA; Khattab, A; Said, MM | 1 |
| Chen, M; Hu, Y; Lan, Y; Liu, Z; Wang, Z; Wen, C; Ye, L | 1 |
| Bai, ZF; Han, YZ; He, LZ; Meng, YK; Sang, XX; Xiao, XH; Yin, P; Zhang, ZF | 1 |
| Hu, JN; Li, W; Liu, WC; Wang, Z; Xing, JJ; Yan, MH | 1 |
| Alpertunga, B; Jannuzzi, AT; Kara, M | 1 |
| Aktas, MS; Dokumacioglu, A; Dokumacioglu, E; Hanedan, B; Iskender, H; Musmul, A; Sen, TM | 1 |
| Cao, P; Huang, X; Sullivan, MA; Sun, J; Wang, H; Wang, K; Wang, N; Zhang, Y | 1 |
| Cui, R; Feng, Y; Liang, H; Liu, C; Qiu, M; Zhang, J | 1 |
| Choi, SM; De, U; Kacew, S; Kim, HS; Kim, MK; Lee, BM; Lim, DS; Lim, SK; Roh, T; Yoon, S | 1 |
| Bian, X; Li, H; Li, P; Liu, J; Wang, S; Zhang, L; Zhao, Y | 1 |
| Aka, C; Koca-Caliskan, U; Sekeroglu, N; Taslidere, A; Yalcin, FN; Yilmaz, I | 1 |
| Kalantari, H; Khodayar, MJ; Khorsandi, L; Rashno, M; Zeidooni, L | 2 |
| Eraslan, G; Kanbur, M; Karabacak, M; Siliğ, Y; Soyer Sarıca, Z; Taş, A; Tekeli, MY | 1 |
| Branco-Neves, S; de Sousa, A; Fidalgo, F; Pereira, R; Soares, C; Teixeira, J | 1 |
| Chen, C; Fu, CL; Hu, JN; Jiang, S; Leng, J; Li, W; Ren, S; Wang, YP; Wang, Z; Zhang, J | 1 |
| Deng, WY; Hu, T; Huang, WQ; Liu, Q; Sun, H | 1 |
| Chen, C; Fu, CL; He, YF; Leng, J; Li, W; Liu, Y; Wang, Z; Zhang, J | 1 |
| Jiang, S; Li, W; Li, YZ; Ma, ZN; Ren, S; Sun, YS; Wang, Z; Zhang, WZ | 1 |
| Borjac, JM; Fahmi, RR; Karaali, HF | 1 |
| Chen, JN; Huang, QH; Lai, XP; Liang, JL; Lin, GS; Liu, YH; Su, ZR; Wu, JZ; Wu, X; Xu, LQ | 1 |
| Chen, C; Hu, JN; Leng, J; Li, W; Liu, Z; Ren, S; Wang, Z; Xu, XY | 1 |
| Liu, H; Wang, XP; Wu, LL; Xie, YN; Zhang, QS | 1 |
| Abdel-Kawy, HS | 1 |
| Ahmed, AAH; Ahmed, AM; Al-Matrafi, TA; Al-Saggaf, S; Alqahtani, HM; AlRabiah, A; Arafah, MM; Atteya, M; Mohammad, RAT; Shereef, SH | 1 |
| Abdel Moneim, AE; Al-Brakati, AY; Elmahallawy, EK; Fouda, MS; Kassab, RB; Tharwat, AM | 1 |
| Jiang, M; Li, MJ; Shen, LP; Wei, MK; Zeng, T; Zhang, MP; Zhao, HJ | 1 |
| Gong, X; Jiang, R; Kuang, G; Wan, J; Wang, Y; Wu, S; Xiong, L; Xu, F; Yang, S; Zeng, T | 1 |
| Che, J; Chen, J; Li, H; Qiao, Z; Sun, J; Wang, C; Yang, S; Zhuang, W | 1 |
| Cheng, Y; Chowdhury, A; Jia, Z; Lu, J; Song, J; Sun, Y; Teng, T; Wang, H; Yin, X; Zhang, R; Zhu, Y | 1 |
| Ding, D; Gai, C; Li, W; Li, Z; Lv, S; Wang, Y; Yu, M; Zhang, W; Zheng, J | 1 |
| Aksakal, M; Arkalı, G; Cellat, M; Gökçek, İ; Güvenç, M; Özkan, H; Yakan, A; Yurdagül Özsoy, Ş | 1 |
| He, HB; Hu, JZ; Huang, WF; Li, JQ; Lu, SG; Ye, JX; Zhao, DX; Zou, K | 1 |
| Cheng, HL; Du, YC; Fu, WG; Lai, L; Qian, BL; Tan, P; Xia, XM; Zhang, H; Zhong, FR | 1 |
| Ahmed, RF; Bakeer, RM; El-Batran, SA; El-Gendy, ZA; Hotaby, WE; Ramadan, A; Youssef, S | 1 |
| Eshrati, R; Ghafourian Hesami, M; Gudarzi, S; Jafari, M; Nazari, A; Samizadeh, E | 1 |
| Abd El-Rhman, RH; Ahmed, LA; El-Yamany, MF; Gad, AM; Hassaneen, SK | 1 |
| Chen, B; Hu, C; Li, X; Liang, L; Liu, X; Yang, D; Zhang, J; Zhang, M | 1 |
| Abd-Eldayem, AM; Ahmed, E; Ahmed, EA | 1 |
| Abdellatif, AAH; Ahmad, AM; Al-Omar, MS; Aly, MSA; Eid, SY; El-Readi, MZ; Eldeeb, HM; Khan, RA; Mohammed, HA; Mohammed, SAA; Sajid, MSM | 1 |
| Chen, C; Li, B; Thida, M; Zhang, X | 1 |
| Hakimizadeh, E; Hassanshahi, J; Kaeidi, A; Najafizadeh, A; Rahmani, M | 1 |
| Ara, J; Azam, M; Ehteshamul-Haque, S; Khan, H; Qureshi, SA; Tariq, A | 1 |
| Gu, H; Lin, T; Wang, XJ; Wang, XL; Zhang, XR | 1 |
| Nithiyanandam, S; Prince, SE | 1 |
1 trial(s) available for acetaminophen and malondialdehyde
| Article | Year |
|---|---|
The effects of spinal, inhalation, and total intravenous anesthetic techniques on ischemia-reperfusion injury in arthroscopic knee surgery.
Topics: Acetaminophen; Adolescent; Adult; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthesia, Spinal; Anesthetics, Inhalation; Anesthetics, Local; Arthroplasty, Replacement, Knee; Aspirin; Bupivacaine; Chlorpheniramine; Dextropropoxyphene; Drug Combinations; Female; Humans; Levobupivacaine; Male; Malondialdehyde; Methyl Ethers; Middle Aged; Reperfusion Injury; Sevoflurane | 2014 |
147 other study(ies) available for acetaminophen and malondialdehyde
| Article | Year |
|---|---|
[Protective action of seed oil of Hippophae rhamnoides L. (HR) against experimental liver injury in mice].
Topics: Acetaminophen; Alanine Transaminase; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Glutathione; Hepatitis, Alcoholic; Male; Malondialdehyde; Mice; Plant Oils | 1992 |
The effect of silibinin (Legalon) on the the free radical scavenger mechanisms of human erythrocytes in vitro.
Topics: Acetaminophen; Adult; Doxorubicin; Erythrocytes; Free Radical Scavengers; Glutathione; Glutathione Peroxidase; Hemolysis; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Lipid Peroxidation; Malondialdehyde; Silymarin; Superoxide Dismutase | 1992 |
[Effects of astragalus (ASI, SK) on experimental liver injury].
Topics: Acetaminophen; Alanine Transaminase; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Galactosamine; Glucosides; Glutathione; Male; Malondialdehyde; Mice; Microsomes, Liver; Rats; Saponins; Triterpenes | 1992 |
Effects of 3-methylcholanthrene or diethyl maleate on the hepatotoxicity of acetaminophen.
Topics: Acetaminophen; Alanine Transaminase; Animals; Drug Synergism; Glutathione; Liver; Male; Maleates; Malondialdehyde; Methylcholanthrene; Mice; Mice, Inbred BALB C | 1992 |
[Acute toxicity of flesh oil of Hippophae rhamnoides L. and its protection against experimental hepatic injury].
Topics: Acetaminophen; Alanine Transaminase; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Female; Glutathione; Liver; Male; Malondialdehyde; Mice; Plant Oils | 1990 |
Effect of deferrioxamine and diethyldithiocarbamate on paracetamol-induced hepato- and nephrotoxicity. The role of lipid peroxidation.
Topics: Acetaminophen; Animals; Creatinine; Deferoxamine; Ditiocarb; Ethane; Glutathione; Kidney; Lipid Peroxides; Liver; Male; Malondialdehyde; Mice | 1988 |
Hamster hepatocytes in culture as a model for acetaminophen toxicity studies with inhibitors of drug metabolism.
Topics: Acetaminophen; Animals; Cells, Cultured; Cricetinae; Cytochrome P-450 Enzyme System; Ditiocarb; Dose-Response Relationship, Drug; Glutathione; L-Lactate Dehydrogenase; Liver; Male; Malondialdehyde; Mesocricetus; Metyrapone; Oxidation-Reduction; Piperonyl Butoxide | 1983 |
Paracetamol-stimulated lipid peroxidation in isolated rat and mouse hepatocytes.
Topics: Acetaminophen; Animals; Drug Interactions; Glutathione; In Vitro Techniques; Lipid Peroxides; Liver; Male; Malondialdehyde; Methylcholanthrene; Mice; Rats; Rats, Inbred Strains; Time Factors | 1983 |
The influence of three prostaglandin biosynthesis stimulators on carrageenin-induced edema of rat paw.
Topics: Acetaminophen; Animals; Butylated Hydroxytoluene; Carrageenan; Edema; Male; Malondialdehyde; Microsomes; Oxygen Consumption; Prostaglandins; Pyrazoles; Pyridines; Rats; Seminal Vesicles; Time Factors | 1980 |
[Protection against experimental hepatic injury by fengxiang yigankang capsule].
Topics: Acetaminophen; Alanine Transaminase; Animals; Capsules; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Glutathione; Liver; Male; Malondialdehyde; Mice | 1994 |
[Sodium ferulate alleviated paracetamol-induced liver toxicity in mice].
Topics: Acetaminophen; Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Coumaric Acids; Glutathione; Glutathione Transferase; Liver; Liver Glycogen; Male; Malondialdehyde; Membrane Fluidity; Mice; Microsomes, Liver | 1994 |
The reaction of malondialdehyde with lens proteins and the protective effect of aspirin.
Topics: Acetaminophen; Animals; Aspirin; Cattle; Crystallins; Ibuprofen; Malondialdehyde | 1993 |
Evidence for potential application of zinc as an antidote to acetaminophen-induced hepatotoxicity.
Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Animals; Antidotes; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Overdose; Drug Therapy, Combination; Glutathione; Liver; Malondialdehyde; Mice; Mice, Inbred ICR; Sulfates; Zinc Compounds; Zinc Sulfate | 1995 |
Effect of acetaminophen administration on hepatic glutathione compartmentation and mitochondrial energy metabolism in the rat.
Topics: Acetaminophen; Adenosine Triphosphate; Animals; Cell Compartmentation; Cytosol; Energy Metabolism; Glutathione; Lipid Peroxidation; Liver; Male; Malondialdehyde; Microscopy, Electron; Mitochondria, Liver; Mitochondrial Swelling; Oxidative Phosphorylation; Rats; Rats, Wistar | 1996 |
Potentiation of acetaminophen hepatotoxicity by acute physical exercise in rats.
Topics: Acetaminophen; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alanine Transaminase; Analgesics; Animals; Aspartate Aminotransferases; Dose-Response Relationship, Drug; Female; Glutathione; Lipid Peroxidation; Liver; Malondialdehyde; Physical Conditioning, Animal; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Time Factors; Vitamin E; Yohimbine | 1997 |
2-Methyl-thiazolidine-2,4-dicarboxylic acid protects against paracetamol induced toxicity in human liver derived HepG2 cells.
Topics: Acetaminophen; Antidotes; Benzoquinones; Cell Line; Cysteine; Glutathione; Humans; Imines; Liver; Malondialdehyde; Oxidation-Reduction; Prodrugs; Reactive Oxygen Species; Thiazoles; Thiazolidines | 1997 |
The effects of glutathione glycoside in acetaminophen-induced liver cell necrosis.
Topics: Acetaminophen; Animals; Drug Overdose; Glutathione; Glycosides; Humans; Lipid Peroxidation; Liver; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Necrosis | 1998 |
[Protective effect of interleukin-1 beta on acetaminophen induced liver damage in mice].
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Glutathione; Interleukin-1; Interleukin-1beta; Lipid Peroxidation; Liver; Male; Malondialdehyde; Mice; Peptide Fragments | 1997 |
Studies on protective effect of DA-9601, Artemisia asiatica extract, on acetaminophen- and CCl4-induced liver damage in rats.
Topics: Acetaminophen; Animals; Artemisia; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Glutathione; Liver; Liver Function Tests; Male; Malondialdehyde; Pharmaceutical Preparations; Plant Extracts; Plants, Medicinal; Rats; Rats, Sprague-Dawley | 1998 |
Combination acetaminophen and doxapram potentiated hepatotoxicity in mouse primary cultured hepatocytes.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Antioxidants; Apoptosis; Calcium; Cell Survival; Cells, Cultured; Central Nervous System Stimulants; Chemical and Drug Induced Liver Injury; DNA Fragmentation; Doxapram; Drug Synergism; Electrophoresis, Agar Gel; Fluorescent Dyes; Iron; Lipid Peroxidation; Liver; Male; Malondialdehyde; Mice; Mice, Inbred C57BL | 1999 |
Repeated acetaminophen dosing in rats: adaptation of hepatic antioxidant system.
Topics: Acetaminophen; Adaptation, Physiological; Alanine Transaminase; Animals; Antioxidants; Body Weight; Catalase; Glucose-6-Phosphatase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Liver; Male; Malondialdehyde; Organ Size; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Up-Regulation | 2000 |
Evaluation of the protective potential of Ambrosia maritima extract on acetaminophen-induced liver damage.
Topics: Acetaminophen; Animals; Asteraceae; Chemical and Drug Induced Liver Injury; Drug Evaluation, Preclinical; Glutathione; Glutathione Peroxidase; Liver; Male; Malondialdehyde; Plant Extracts; Rats; Rats, Sprague-Dawley | 2001 |
Protective effect of polysaccharides-enriched fraction from Angelica sinensis on hepatic injury.
Topics: Acetaminophen; Administration, Oral; Alanine Transaminase; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Glutathione; Glycosaminoglycans; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Plant Extracts; Plant Roots; Rats; Rats, Sprague-Dawley | 2001 |
Effects of paracetamol and propacetamol on gastric mucosal damage and gastric lipid peroxidation caused by acetylsalicylic acid (ASA) in rats.
Topics: Acetaminophen; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dinoprostone; Dose-Response Relationship, Drug; Gastric Mucosa; Glutathione; Lipid Peroxidation; Male; Malondialdehyde; Peptic Ulcer; Rats; Rats, Wistar; Uric Acid | 2002 |
[Effect of stilbene polymer (Gn-3) on experimental liver injuries in mice].
Topics: Acetaminophen; Alanine Transaminase; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Gnetum; Lipopolysaccharides; Liver; Male; Malondialdehyde; Mice; Mycobacterium bovis; Plants, Medicinal; Protective Agents; Random Allocation; Stilbenes | 2001 |
Protective effect of arabic gum against acetaminophen-induced hepatotoxicity in mice.
Topics: Acetaminophen; Administration, Oral; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Glutathione; Gum Arabic; Liver; Liver Diseases; Male; Malondialdehyde; Mice; Nitrates; Nitrites; Protective Agents; Random Allocation | 2003 |
[The flavonoids effect against vinblastine, cyclophosphamide and paracetamol toxicity by inhibition of lipid-peroxydation and increasing liver glutathione concentration].
Topics: Acetaminophen; Animals; Cyclophosphamide; Diosmin; Female; Flavonols; Glutathione; Hepatocytes; Kinetics; Lipid Peroxidation; Liver; Malondialdehyde; Models, Animal; Quercetin; Rats; Rats, Wistar; Time Factors; Vinblastine | 2004 |
Protective effect of s-allyl cysteine and s-propyl cysteine on acetaminophen-induced hepatotoxicity in mice.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Aspartate Aminotransferases; C-Reactive Protein; Cysteine; Glutathione; Glutathione Peroxidase; Liver; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Oxidation-Reduction; Oxidative Stress; Protective Agents | 2006 |
Effect of Cistus laurifolius L. leaf extracts and flavonoids on acetaminophen-induced hepatotoxicity in mice.
Topics: Acetaminophen; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cistus; Flavonoids; Flavonols; Glutathione; Kaempferols; Lipid Peroxidation; Liver; Liver Diseases; Male; Malondialdehyde; Mice; Plant Extracts; Plant Leaves; Quercetin; Turkey | 2006 |
Protective effects of ginkgo biloba against acetaminophen-induced toxicity in mice.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Antioxidants; Female; Ginkgo biloba; Glutathione; Liver; Luminescence; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Oxidation-Reduction; Oxidative Stress; Peroxidase; Plant Extracts | 2006 |
Acetaminophen-induced toxicity is prevented by beta-D-glucan treatment in mice.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Antioxidants; Aspartate Aminotransferases; beta-Glucans; Collagen; Glutathione; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Luminescent Measurements; Malondialdehyde; Mice; Mice, Inbred BALB C; Oxidative Stress; Peroxidase; Reactive Oxygen Species; Tumor Necrosis Factor-alpha | 2006 |
Hepatoprotective and antioxidant effects of Cuscuta chinensis against acetaminophen-induced hepatotoxicity in rats.
Topics: Acetaminophen; Administration, Oral; Animals; Antioxidants; Biomarkers; Catalase; Chemical and Drug Induced Liver Injury; Cuscuta; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Glutathione Peroxidase; Lipid Peroxidation; Liver; Liver Diseases; Male; Malondialdehyde; Oxidative Stress; Plant Extracts; Rats; Rats, Wistar; Seeds; Solvents; Superoxide Dismutase; Taiwan; Water | 2007 |
Recombinant platelet-activating factor-acetylhydrolase attenuates paracetamol-induced liver oxidative stress, injury, and regeneration.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acetaminophen; Analgesics, Non-Narcotic; Animals; Liver; Liver Regeneration; Male; Malondialdehyde; Necrosis; Oxidative Stress; Rats; Rats, Wistar; Recombinant Proteins | 2007 |
Platelet-activating factor inactivator (rPAF-AH) enhances liver's recovery after paracetamol intoxication.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acetaminophen; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Colorimetry; Disease Models, Animal; DNA; Dose-Response Relationship, Drug; Hepatocytes; Injections, Intraperitoneal; Liver; Male; Malondialdehyde; Mitosis; Oxidative Stress; Rats; Rats, Wistar; Recombinant Proteins; Recovery of Function; Thymidine Kinase; Transaminases; Ultracentrifugation | 2007 |
Hepatoprotective effect of L-carnitine against acute acetaminophen toxicity in mice.
Topics: Acetaminophen; Acute Disease; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Aspartate Aminotransferases; Carnitine; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drug Antagonism; Glutathione; Hemorrhage; Injections, Intraperitoneal; Liver; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; N-Acetylneuraminic Acid; Necrosis; Vitamin B Complex | 2007 |
Nanoparticles formulation of Cuscuta chinensis prevents acetaminophen-induced hepatotoxicity in rats.
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Analgesics, Non-Narcotic; Animals; Antioxidants; Aspartate Aminotransferases; Catalase; Chemical and Drug Induced Liver Injury; Chemistry, Pharmaceutical; Cuscuta; Glutathione Peroxidase; Lipid Peroxidation; Liver; Liver Function Tests; Male; Malondialdehyde; Nanoparticles; Oxidative Stress; Particle Size; Plant Extracts; Rats; Rats, Wistar; Superoxide Dismutase | 2008 |
Propolis reverses acetaminophen induced acute hepatorenal alterations: a biochemical and histopathological approach.
Topics: Acetaminophen; Acid Phosphatase; Adenosine Triphosphatases; Alkaline Phosphatase; Animals; Antioxidants; Bilirubin; Blood Glucose; Chemical and Drug Induced Liver Injury; Cholesterol; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Female; Glutathione; Glycogen; Hemoglobins; Kidney; Kidney Diseases; L-Lactate Dehydrogenase; Liver; Liver Diseases; Malondialdehyde; Oxidative Stress; Propolis; Rats; Rats, Sprague-Dawley; Silymarin; Transaminases | 2008 |
Preventive effect of Ganoderma amboinense on acetaminophen-induced acute liver injury.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Catalase; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Flavonoids; Ganoderma; Glutathione; Glutathione Peroxidase; Liver; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Polyphenols; Protective Agents; Reactive Oxygen Species | 2008 |
Carnitine deficiency: a possible risk factor in paracetamol hepatotoxicity.
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Analgesics, Non-Narcotic; Animals; Aspartate Aminotransferases; Biomarkers; Carnitine; Chemical and Drug Induced Liver Injury; Drug Synergism; Glutathione; Lipid Peroxidation; Liver; Male; Malondialdehyde; Nitric Oxide; Peroxidase; Rats; Rats, Inbred Strains; Risk Factors; Tumor Necrosis Factor-alpha | 2009 |
Effects of erdosteine on acetaminophen-induced hepatotoxicity in rats.
Topics: Acetaminophen; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Catalase; Dose-Response Relationship, Drug; Drug Interactions; Female; Glutathione Peroxidase; Liver; Malondialdehyde; Necrosis; Nitric Oxide; Oxidants; Rats; Rats, Wistar; Superoxide Dismutase; Thioglycolates; Thiophenes | 2008 |
Protective effects of salidroside against acetaminophen-induced toxicity in mice.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Aspartate Aminotransferases; Caspase 3; Chemical and Drug Induced Liver Injury; Glucosides; Glutathione; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Lipid Peroxidation; Liver; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Oxidative Stress; Phenols; Rhodiola; Tumor Necrosis Factor-alpha | 2008 |
The effects of acute acetaminophen toxicity on hepatic mRNA expression of SOD, CAT, GSH-Px, and levels of peroxynitrite, nitric oxide, reduced glutathione, and malondialdehyde in rabbit.
Topics: Acetaminophen; Animals; Catalase; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Liver; Male; Malondialdehyde; Nitric Oxide; Nitrites; Peroxynitrous Acid; Rabbits; RNA; Superoxide Dismutase | 2009 |
Liver antioxidant capacity in the early phase of acute paracetamol-induced liver injury in mice.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Antioxidants; Lipid Peroxidation; Liver; Male; Malondialdehyde; Mice; Sulfhydryl Compounds; Superoxide Dismutase | 2009 |
Hepatoprotective effects of an anthocyanin fraction from purple-fleshed sweet potato against acetaminophen-induced liver damage in mice.
Topics: Acetaminophen; Alanine Transaminase; Aniline Compounds; Animals; Anthocyanins; Aspartate Aminotransferases; Carcinogens; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Free Radical Scavengers; Glutathione; Glutathione Transferase; Ipomoea batatas; Lipid Peroxidation; Liver; Liver Diseases; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Phytotherapy; Plant Extracts; Protective Agents | 2009 |
Protective Effects of the Supernatant of Ethanol Eluate from Artemisia sacrorum Ledeb. against Acetaminophen-Induced Liver Injury in Mice [corrected].
Topics: Acetaminophen; Alanine Transaminase; Animals; Apoptosis; Artemisia; Aspartate Aminotransferases; Caspase 3; Caspase 8; Chemical and Drug Induced Liver Injury; DNA; Glutathione; Liver; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Necrosis; Phytotherapy; Plant Components, Aerial; Plant Extracts; Protective Agents; Tumor Necrosis Factor-alpha | 2009 |
Acanthoic acid, a diterpene in Acanthopanax koreanum, protects acetaminophen-induced hepatic toxicity in mice.
Topics: Acetaminophen; Animals; Antioxidants; Caspase 3; Chemical and Drug Induced Liver Injury; Diterpenes; Eleutherococcus; Hypoxia-Inducible Factor 1, alpha Subunit; Liver; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Necrosis; Oxidative Stress; Phytotherapy; Plant Bark; Plant Extracts; Plant Roots | 2010 |
Curcumin protects rats against acetaminophen-induced hepatorenal damages and shows synergistic activity with N-acetyl cysteine.
Topics: Acetaminophen; Acetylcysteine; Animals; Biomarkers; Catalase; Curcumin; Drug Synergism; Glutathione Peroxidase; Kidney; Kidney Diseases; Liver; Liver Diseases; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Sprague-Dawley; Serologic Tests | 2010 |
Repeated preexposure or coexposure to arsenic differentially alters acetaminophen-induced oxidative stress in rat kidney.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Arsenic; Catalase; Cytochrome P-450 Enzyme System; Drug Interactions; Environmental Pollutants; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Kidney; Lipid Peroxidation; Liver; Male; Malondialdehyde; Microsomes, Liver; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase | 2011 |
Gentiana manshurica Kitagawa prevents acetaminophen-induced acute hepatic injury in mice via inhibiting JNK/ERK MAPK pathway.
Topics: Acetaminophen; Alanine Transaminase; Aldehydes; Animals; Apoptosis; Aspartate Aminotransferases; Caspase 3; Caspase Inhibitors; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drugs, Chinese Herbal; Extracellular Signal-Regulated MAP Kinases; Gentiana; Glutathione; Glutathione Peroxidase; Male; Malondialdehyde; MAP Kinase Kinase 4; Mice; Mice, Inbred Strains; Signal Transduction | 2010 |
Protection by dietary Spirulina platensis against D-galactosamine--and acetaminophen-induced liver injuries.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Diet; Galactosamine; Interleukin-18; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; RNA, Messenger; Spirulina; Thiobarbituric Acid Reactive Substances | 2010 |
Endothelin-A receptor antagonist BQ123 potentiates acetaminophen induced hypothermia and reduces infarction following focal cerebral ischemia in rats.
Topics: Acetaminophen; Animals; Antipyretics; Brain Ischemia; Disease Models, Animal; Drug Synergism; Endothelin A Receptor Antagonists; Glutathione; Hypothermia, Induced; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Oxidative Stress; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Stroke | 2010 |
Comparison of the protective actions of N-acetylcysteine, hypotaurine and taurine against acetaminophen-induced hepatotoxicity in the rat.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Glutathione Transferase; Humans; Liver; Liver Diseases; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Taurine | 2010 |
Curative effects of hydrogen sulfide against acetaminophen-induced hepatotoxicity in mice.
Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Animals; Anti-Inflammatory Agents; Antidotes; Antioxidants; Chemical and Drug Induced Liver Injury; Cyclooxygenase 2; Glutathione; Hepatocytes; Hydrogen Sulfide; Male; Malondialdehyde; Mice; Nitric Oxide; Tumor Necrosis Factor-alpha | 2010 |
Anti-hepatotoxic effects of 3,4-methylenedioxyphenol and N-acetylcysteine in acutely acetaminophen-overdosed mice.
Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Antioxidants; Aspartate Aminotransferases; Benzodioxoles; Chemical and Drug Induced Liver Injury; Glutathione; Lipid Peroxidation; Male; Malondialdehyde; Mice; Mice, Inbred C3H; Phenols | 2011 |
Susceptibility of rat non-alcoholic fatty liver to the acute toxic effect of acetaminophen.
Topics: Acetaminophen; Animals; Biomarkers; Caspase 3; Chemical and Drug Induced Liver Injury; Cholesterol; Disease Models, Animal; Disease Susceptibility; Electron Transport Chain Complex Proteins; Fatty Liver; Glutathione; Glutathione Disulfide; Liver; Male; Malondialdehyde; Necrosis; Non-alcoholic Fatty Liver Disease; Rats; Rats, Sprague-Dawley; Risk Factors; Severity of Illness Index; Time Factors; Transforming Growth Factor beta1; Triglycerides; Tumor Necrosis Factor-alpha | 2012 |
Protective effects of 2,4-dihydroxybenzophenone against acetaminophen-induced hepatotoxicity in mice.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Benzophenones; Chemical and Drug Induced Liver Injury; Glutathione; Humans; Liver; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Oxidative Stress | 2011 |
Hepatoprotective effect of coenzyme Q10 in rats with acetaminophen toxicity.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Biomarkers; Caspase 3; Catalase; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Drug Administration Schedule; Glutathione; Immunohistochemistry; Injections, Intraperitoneal; Lipid Peroxidation; Liver; Male; Malondialdehyde; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Rats, Sprague-Dawley; Selenium; Time Factors; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; Ubiquinone; Zinc | 2012 |
Nephroprotective effects of Zingiber zerumbet Smith ethyl acetate extract against paracetamol-induced nephrotoxicity and oxidative stress in rats.
Topics: Acetaminophen; Acetates; Acute Kidney Injury; Analgesics, Non-Narcotic; Animals; Antioxidants; Creatinine; Glutathione; Male; Malondialdehyde; Oxidative Stress; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Zingiberaceae | 2012 |
Effect of Asparagus falcatus on acetaminophen toxicity in mice: a comparison of antioxidative effect with N-acetyl cysteine.
Topics: Acetaminophen; Acetylcysteine; Analysis of Variance; Animals; Antioxidants; Asparagus Plant; Chemical and Drug Induced Liver Injury; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Phytotherapy; Plant Extracts | 2008 |
The protective effects of ozone therapy in a rat model of acetaminophen-induced liver injury.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Glutathione Peroxidase; Liver; Male; Malondialdehyde; Necrosis; Neopterin; Nitrates; Nitrites; Ozone; Protective Agents; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2012 |
Effects of non-steroidal antiinflammatory drugs on D-serine-induced oxidative stress in vitro.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Inflammation; Lipid Peroxidation; Malondialdehyde; Mefenamic Acid; Naproxen; Neuroprotective Agents; Oxidative Stress; Protein Carbonylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Serine | 2012 |
Protective effects of 5-methoxypsoralen against acetaminophen-induced hepatotoxicity in mice.
Topics: 5-Methoxypsoralen; Acetaminophen; Administration, Oral; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Biomarkers; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Glutathione; Glutathione Disulfide; L-Lactate Dehydrogenase; Liver; Male; Malondialdehyde; Methoxsalen; Mice; Mice, Inbred C57BL; Oxidative Stress | 2012 |
Moringa oleifera hydroethanolic extracts effectively alleviate acetaminophen-induced hepatotoxicity in experimental rats through their antioxidant nature.
Topics: Acetaminophen; Aldehydes; Animals; Antioxidants; Biomarkers; Biphenyl Compounds; Ethanol; Flowers; Fluorescence Recovery After Photobleaching; Free Radical Scavengers; Glutathione; Liver; Liver Diseases; Liver Function Tests; Male; Malondialdehyde; Moringa oleifera; Oxidative Stress; Phenols; Phytotherapy; Picrates; Plant Extracts; Rats; Rats, Sprague-Dawley; Water | 2012 |
Protective effects of a purified saponin mixture from Astragalus corniculatus Bieb., in vivo hepatotoxicity models.
Topics: Acetaminophen; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Astragalus Plant; Biotransformation; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Glutathione; L-Lactate Dehydrogenase; Liver; Liver Function Tests; Male; Malondialdehyde; Plant Extracts; Rats; Rats, Wistar; Saponins; Silymarin | 2013 |
Therapeutic role of telmisartan against acetaminophen hepatotoxicity in mice.
Topics: Acetaminophen; Alanine Transaminase; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agents; Antioxidants; Benzimidazoles; Benzoates; Catalase; Chemical and Drug Induced Liver Injury; Glutathione; Liver; Male; Malondialdehyde; Mice; Nitric Oxide; Superoxide Dismutase; Telmisartan | 2012 |
Potential protective effect of honey against paracetamol-induced hepatotoxicity.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Antioxidants; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Glutathione; Glutathione Peroxidase; Honey; Interleukin-1beta; Liver; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Silymarin | 2012 |
Protective effect of naringenin against acetaminophen-induced acute liver injury in metallothionein (MT)-null mice.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Flavanones; Glutathione; Humans; Liver; Male; Malondialdehyde; Metallothionein; Mice; Mice, Knockout; Protective Agents | 2013 |
Ameliorative potential of whey protein hydrolysate against paracetamol-induced oxidative stress.
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Animals; Blood Urea Nitrogen; Creatinine; Liver; Male; Malondialdehyde; Mice; Milk Proteins; Oxidative Stress; Whey Proteins | 2013 |
Comparative evaluation of the effects of taurine and thiotaurine on alterations of the cellular redox status and activities of antioxidant and glutathione-related enzymes by acetaminophen in the rat.
Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Catalase; Glutamate-Cysteine Ligase; Glutathione; Glutathione Disulfide; Glutathione Reductase; Glutathione Transferase; L-Lactate Dehydrogenase; Liver; Male; Malondialdehyde; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Taurine | 2013 |
The role of infliximab on paracetamol-induced hepatotoxicity in rats.
Topics: Acetaminophen; Animals; Antibodies, Monoclonal; Antioxidants; Chemical and Drug Induced Liver Injury; Cytokines; Immunohistochemistry; Infliximab; Lipid Peroxides; Liver; Liver Function Tests; Male; Malondialdehyde; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2013 |
The ameliorative effects of L-2-oxothiazolidine-4-carboxylate on acetaminophen-induced hepatotoxicity in mice.
Topics: Acetaminophen; Alanine Transaminase; Aldehydes; Analgesics, Non-Narcotic; Animals; Antioxidants; Apoptosis; Aspartate Aminotransferases; Caspase 3; Chemical and Drug Induced Liver Injury; DNA Fragmentation; Glutathione; Glutathione Peroxidase; Liver; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Necrosis; Oxidative Stress; Pyrrolidonecarboxylic Acid; Thiazolidines; Tyrosine | 2013 |
Curcumin attenuated paracetamol overdose induced hepatitis.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Curcumin; Drug Evaluation, Preclinical; Drug Overdose; Glutathione; Interleukin-12; Interleukin-18; Liver; Male; Malondialdehyde; Mice; Phytotherapy; Plant Extracts; Transaminases | 2013 |
Protective effect of apigenin on mouse acute liver injury induced by acetaminophen is associated with increment of hepatic glutathione reductase activity.
Topics: Acetaminophen; Alanine Transaminase; Animals; Apigenin; Chemical and Drug Induced Liver Injury; Glutathione Reductase; Glutathione Transferase; Humans; Liver; Male; Malondialdehyde; Mice; Protective Agents | 2013 |
Hepatoprotective effects of kombucha tea: identification of functional strains and quantification of functional components.
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Beverages; Camellia sinensis; Chemical and Drug Induced Liver Injury; Fermentation; Glucaric Acid; Gluconacetobacter; Lactones; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Plant Extracts; Tea; Triglycerides; Yeasts | 2014 |
Effect of newly isolated Lactobacillus ingluviei ADK10, from chicken intestinal tract on acetaminophen induced oxidative stress in Wistar rats.
Topics: Acetaminophen; Animals; Antioxidants; Catalase; Chickens; Glutathione; Intestines; Kidney; Lactobacillus; Liver; Male; Malondialdehyde; Molecular Sequence Data; Oxidation-Reduction; Oxidative Stress; Phylogeny; Rats; Rats, Wistar; Superoxide Dismutase | 2013 |
Hepatoprotective, antioxidant, and ameliorative effects of ginger (Zingiber officinale Roscoe) and vitamin E in acetaminophen treated rats.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Antioxidants; Aspartate Aminotransferases; Bilirubin; Blood Proteins; Chemical and Drug Induced Liver Injury; Lipid Peroxidation; Liver; Male; Malondialdehyde; Necrosis; Oxidative Stress; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Triglycerides; Vitamin E; Zingiber officinale | 2013 |
Protective effects of BML-111 against acetaminophen-induced acute liver injury in mice.
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Drug Evaluation, Preclinical; Glutathione; Heptanoic Acids; Liver; Male; Malondialdehyde; Mice; Nitric Oxide; Oxidative Stress; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2014 |
Curcumin protects against acetaminophen-induced apoptosis in hepatic injury.
Topics: Acetaminophen; Alanine Transaminase; Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Biomarkers; Chemical and Drug Induced Liver Injury; Curcumin; Cytoprotection; Disease Models, Animal; Hepatocytes; Lipid Peroxidation; Liver; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Necrosis; Oxidative Stress; Protective Agents; Proto-Oncogene Proteins c-bcl-2; Superoxide Dismutase | 2013 |
Hepatoprotective action of Echinophora platyloba DC leaves against acute toxicity of acetaminophen in rats.
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Analysis of Variance; Animals; Antioxidants; Apiaceae; Aspartate Aminotransferases; Catalase; Chemical and Drug Induced Liver Injury; Liver; Malondialdehyde; Phytotherapy; Plant Extracts; Plant Leaves; Rats | 2014 |
Insights in the mechanism underlying the protective effect of α-lipoic acid against acetaminophen-hepatotoxicity.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cytoprotection; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Glutathione; Liver; Male; Malondialdehyde; NF-kappa B; Oxidative Stress; Rats; Rats, Wistar; Thioctic Acid | 2014 |
Two xanthones from Swertia punicea with hepatoprotective activities in vitro and in vivo.
Topics: Acetaminophen; Animals; Aspartate Aminotransferases; Bilirubin; Carbon Tetrachloride; Cell Survival; Dimethylnitrosamine; Glutathione; Hep G2 Cells; Humans; L-Lactate Dehydrogenase; Liver; Liver Cirrhosis; Male; Malondialdehyde; Protective Agents; Rats, Wistar; Reactive Oxygen Species; Serum Albumin; Superoxide Dismutase; Swertia; Xanthones | 2014 |
Therapeutic potential of different commercially available synbiotic on acetaminophen-induced uremic rats.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Urea Nitrogen; Catalase; Creatinine; DNA Fragmentation; Feces; Glutathione; Kidney Glomerulus; Male; Malondialdehyde; Necrosis; Rats; Rats, Wistar; Superoxide Dismutase; Synbiotics; Urea; Uremia | 2015 |
Effect of acetaminophen exposure in Oncorhynchus mykiss gills and liver: detoxification mechanisms, oxidative defence system and peroxidative damage.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Catalase; Gills; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Lipid Peroxidation; Liver; Malondialdehyde; Oncorhynchus mykiss; Oxidative Stress; Thiobarbituric Acid Reactive Substances | 2014 |
Biochemical and standard toxic effects of acetaminophen on the macrophyte species Lemna minor and Lemna gibba.
Topics: Acetaminophen; Analysis of Variance; Antipyretics; Araceae; Chlorophyll; Lipid Peroxidation; Malondialdehyde; Oxidative Stress; Plant Leaves; Proline; Species Specificity; Thiobarbituric Acid Reactive Substances; Toxicity Tests, Acute; Water Pollutants, Chemical | 2014 |
Aloe vera attenuated liver injury in mice with acetaminophen-induced hepatitis.
Topics: Acetaminophen; Aloe; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Glutathione; Hepatitis; Interleukin-12; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Oxidative Stress; Plant Extracts; Random Allocation; Transaminases | 2014 |
Pleurotus ostreatus opposes mitochondrial dysfunction and oxidative stress in acetaminophen-induced hepato-renal injury.
Topics: Acetaminophen; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Biological Products; Chemical and Drug Induced Liver Injury; Dietary Supplements; Glutathione; Glutathione Peroxidase; Kidney; Kidney Diseases; Liver; Male; Malondialdehyde; Mice; Mitochondria; Necrosis; Oxidation-Reduction; Oxidative Stress; Phytotherapy; Pleurotus | 2014 |
Effect of homopterocarpin, an isoflavonoid from Pterocarpus erinaceus, on indices of liver injury and oxidative stress in acetaminophen-provoked hepatotoxicity.
Topics: Acetaminophen; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Benzofurans; Benzopyrans; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Male; Malondialdehyde; Oxidative Stress; Plant Extracts; Pterocarpus; Rats; Rats, Wistar | 2015 |
In vitro antioxidant and hepatoprotective potential of Azolla microphylla phytochemically synthesized gold nanoparticles on acetaminophen - induced hepatocyte damage in Cyprinus carpio L.
Topics: Acetaminophen; Animals; Antioxidants; Carps; Catalase; Ferns; Glutathione Peroxidase; Gold; Hepatocytes; L-Lactate Dehydrogenase; Liver; Malondialdehyde; Metal Nanoparticles; Methanol; Phytochemicals; Protective Agents; Reactive Oxygen Species; Spectrometry, X-Ray Emission; Superoxide Dismutase | 2015 |
Antioxidant and hepatoprotective activity of vitex honey against paracetamol induced liver damage in mice.
Topics: Acetaminophen; Animals; Antioxidants; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; China; Glutathione Peroxidase; Honey; Humans; Liver; Male; Malondialdehyde; Mice; Protective Agents; Superoxide Dismutase; Vitex | 2015 |
Biochemical and Histological Effects of Thiamine Pyrophosphate against Acetaminophen-Induced Hepatotoxicity.
Topics: Acetaminophen; Acetylcysteine; Animals; Antioxidants; Catalase; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Female; Glutathione; Liver; Liver Function Tests; Malondialdehyde; Nitric Oxide; Oxidative Stress; Peroxidase; Rats, Wistar; Thiamine Pyrophosphate | 2016 |
Protective effects of hydrogen sulfide anions against acetaminophen-induced hepatotoxicity in mice.
Topics: Acetaminophen; Acute Disease; Animals; Benzoquinones; Cytochrome P-450 Enzyme System; Female; Glutathione; Humans; Imines; Liver; Male; Malondialdehyde; Mice, Inbred C57BL; Mice, Knockout; Sulfides | 2015 |
Mitigation of paracetamol-induced reproductive damage by chrysin in male rats via reducing oxidative stress.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Apoptosis; Dose-Response Relationship, Drug; Flavonoids; Male; Malondialdehyde; Oxidative Stress; Rats; Sperm Motility; Spermatozoa; Testis | 2016 |
Paracetamol-induced nephrotoxicity and oxidative stress in rats: the protective role of Nigella sativa.
Topics: Acetaminophen; Acetylcysteine; Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Creatinine; Cytoprotection; Disease Models, Animal; Ethanol; Female; Glutathione; Kidney; Kidney Diseases; Malondialdehyde; Nigella sativa; Phytotherapy; Plant Extracts; Plants, Medicinal; Rats, Wistar; Seeds; Solvents; Superoxide Dismutase; Urea | 2016 |
Ameliorative effect of naringin in acetaminophen-induced hepatic and renal toxicity in laboratory rats: role of FXR and KIM-1.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Aspartate Aminotransferases; Cell Adhesion Molecules; Chemical and Drug Induced Liver Injury; Creatinine; Flavanones; Glutathione; Kidney; Kidney Diseases; Lipid Peroxidation; Lipoproteins, HDL; Lipoproteins, LDL; Liver; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Uric Acid | 2016 |
Redox Nanoparticle Therapeutics for Acetaminophen-Induced Hepatotoxicity in Mice.
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Glutathione Peroxidase; Liver; Liver Function Tests; Male; Malondialdehyde; Mice; Nanoparticles; Oxidation-Reduction; Particle Size; Protective Agents; Prothrombin Time; Serum Albumin; Superoxides | 2016 |
Attenuating Oxidative Stress by Paeonol Protected against Acetaminophen-Induced Hepatotoxicity in Mice.
Topics: Acetaminophen; Acetophenones; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Glutathione; Glutathione Peroxidase; Liver; Male; Malondialdehyde; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; NF-kappa B; Oxidative Stress; Superoxide Dismutase | 2016 |
Baicalin Attenuates IL-17-Mediated Acetaminophen-Induced Liver Injury in a Mouse Model.
Topics: Acetaminophen; Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Flavonoids; Flow Cytometry; Immunohistochemistry; Interleukin-17; Interleukin-6; Liver; Liver Regeneration; Male; Malondialdehyde; Mice, Inbred C57BL; Peroxidase; Receptors, Antigen, T-Cell, gamma-delta; Superoxide Dismutase; T-Lymphocytes; Tumor Necrosis Factor-alpha | 2016 |
Different effects of selective β1-adrenoceptor antagonists, nebivolol or atenolol in acetaminophen-induced hepatotoxicity of rats.
Topics: Acetaminophen; Adrenergic beta-1 Receptor Antagonists; Analgesics, Non-Narcotic; Animals; Antioxidants; Atenolol; Blood Pressure; Chemical and Drug Induced Liver Injury; Drug Overdose; Glutathione; Heart Rate; Male; Malondialdehyde; Nebivolol; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Rats, Wistar | 2017 |
Formononetin protects against acetaminophen-induced hepatotoxicity through enhanced NRF2 activity.
Topics: Acetaminophen; Alanine Transaminase; Animals; Antioxidants; Apoptosis; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Gene Expression Regulation; Glutathione; Humans; Isoflavones; Liver; Malondialdehyde; Mice; NF-E2-Related Factor 2; Oxidative Stress | 2017 |
Multi-targeted protection of acetaminophen-induced hepatotoxicity in mice by tannic acid.
Topics: Acetaminophen; Alanine Transaminase; Animals; Anti-Inflammatory Agents; Apoptosis; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Endothelin-1; Heme Oxygenase-1; Humans; Inflammation Mediators; Malondialdehyde; Mice; Mice, Inbred Strains; Nitric Oxide; Oxidative Stress; Superoxide Dismutase; Tannins | 2017 |
Saponins (Ginsenosides) from the Leaves of Panax quinquefolius Ameliorated Acetaminophen-Induced Hepatotoxicity in Mice.
Topics: Acetaminophen; Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cyclooxygenase 2; Ginsenosides; Glutathione; Humans; Interleukin-1beta; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Oxidative Stress; Panax; Tumor Necrosis Factor-alpha | 2017 |
Anti-oxidative and anti-inflammatory benefits of the ribonucleoside analogue 5-azacitidine in mice with acetaminophen-induced toxic hepatitis.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Antioxidants; Azacitidine; Chemical and Drug Induced Liver Injury; Glutathione; Interleukin-6; Liver; Male; Malondialdehyde; Mice, Inbred C57BL; Nitric Oxide; Oxidative Stress; Peroxidase; Tumor Necrosis Factor-alpha | 2017 |
PROTECTIVE EFFECT OF
Topics: Acetaminophen; Animals; Antioxidants; Catalase; Chemical and Drug Induced Liver Injury; DNA Fragmentation; Female; Glutathione; Glutathione Peroxidase; Liver; Malondialdehyde; Moringa; Oxidative Stress; Phytotherapy; Plant Extracts; Plant Leaves; Rats; Superoxides | 2017 |
Eriodictyol, Not Its Glucuronide Metabolites, Attenuates Acetaminophen-Induced Hepatotoxicity.
Topics: Acetaminophen; Animals; Flavanones; Glucuronides; Glucuronosyltransferase; Glutathione; Glutathione Transferase; Glycyrrhetinic Acid; Liver; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Superoxide Dismutase | 2017 |
[Protective effects of luteolin against acetaminophen-induced damage in L02 liver cells].
Topics: Acetaminophen; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Line; Hepatocytes; Humans; Liver; Luteolin; Malondialdehyde; Protective Agents; Proto-Oncogene Proteins c-bcl-2; Superoxide Dismutase | 2016 |
Caspase-Mediated Anti-Apoptotic Effect of Ginsenoside Rg5, a Main Rare Ginsenoside, on Acetaminophen-Induced Hepatotoxicity in Mice.
Topics: Acetaminophen; Animals; Apoptosis; Caspase 3; Caspase 8; Caspase 9; Chemical and Drug Induced Liver Injury; Ginsenosides; Humans; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Oxidative Stress; Panax | 2017 |
Celastrol ameliorates acetaminophen-induced oxidative stress and cytotoxicity in HepG2 cells.
Topics: Acetaminophen; Antioxidants; Catalase; Cell Survival; Chemical and Drug Induced Liver Injury; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Hep G2 Cells; Humans; Malondialdehyde; Oxidative Stress; Pentacyclic Triterpenes; Protein Carbonylation; Superoxide Dismutase; Triterpenes | 2018 |
The effect of sulforaphane on oxidative stress and inflammation in rats with toxic hepatitis induced by acetaminophene.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Antioxidants; Aspartate Aminotransferases; C-Reactive Protein; Chemical and Drug Induced Liver Injury; Inflammation; Isothiocyanates; Liver; Male; Malondialdehyde; Neopterin; Oxidative Stress; Plant Extracts; Protective Agents; Rats; Rats, Sprague-Dawley; Sulfoxides | 2017 |
Angelica sinensis polysaccharide protects against acetaminophen-induced acute liver injury and cell death by suppressing oxidative stress and hepatic apoptosis in vivo and in vitro.
Topics: Acetaminophen; Angelica sinensis; Animals; Apoptosis; Chemical and Drug Induced Liver Injury; Glutathione; Hepatocytes; Humans; Lipid Peroxidation; Liver; Malondialdehyde; Oxidative Stress; Polysaccharides; Protective Agents; Rats; Water | 2018 |
Simvastatin protects against acetaminophen-induced liver injury in mice.
Topics: Acetaminophen; Alanine Transaminase; Animals; Antioxidants; Apoptosis; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Glutathione; Liver; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Oxidative Stress; Protective Agents; Simvastatin; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2018 |
Detoxifying effect of pyridoxine on acetaminophen-induced hepatotoxicity via suppressing oxidative stress injury.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cytochromes c; Glutathione; Glutathione Peroxidase; Hep G2 Cells; Humans; Lipid Peroxidation; Liver; Male; Malondialdehyde; Mice, Inbred ICR; Oxidative Stress; Pyridoxine | 2018 |
Hepatoprotective effect of chiisanoside against acetaminophen-induced acute liver injury in mice.
Topics: Acetaminophen; Alanine Transaminase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspartate Aminotransferases; Catalase; Chemical and Drug Induced Liver Injury; Glutathione; Liver; Male; Malondialdehyde; Mice, Inbred ICR; NF-kappa B; Oligosaccharides; Oxidative Stress; Protective Agents; Superoxide Dismutase; Triterpenes; Tumor Necrosis Factor-alpha | 2019 |
Cuscuta arvensis Beyr "Dodder": In Vivo Hepatoprotective Effects Against Acetaminophen-Induced Hepatotoxicity in Rats.
Topics: Acetaminophen; Alkaline Phosphatase; Animals; Antioxidants; Aspartate Aminotransferases; Bilirubin; Catalase; Chemical and Drug Induced Liver Injury; Cuscuta; Female; Humans; Liver; Malondialdehyde; Plant Extracts; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2018 |
Betaine protects mice against acetaminophen hepatotoxicity possibly via mitochondrial complex II and glutathione availability.
Topics: Acetaminophen; Animals; Betaine; Catalase; Chemical and Drug Induced Liver Injury; Electron Transport Complex II; Glutamate-Cysteine Ligase; Glutathione; Glutathione Peroxidase; Liver; Male; Malondialdehyde; Membrane Potential, Mitochondrial; Mice; Mitochondria, Liver; Models, Biological; Protective Agents; Reactive Oxygen Species; Superoxide Dismutase | 2018 |
The effects of colostrum on some biochemical parameters in the experimental intoxication of rats with paracetamol.
Topics: Acetaminophen; Animals; Blood Urea Nitrogen; Colostrum; Enzymes; Female; Glutathione; Lipid Peroxidation; Liver; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Rats, Wistar; Triglycerides | 2018 |
Can nano-SiO
Topics: Acetaminophen; Analgesics, Non-Narcotic; Antioxidants; Ascorbate Peroxidases; Ascorbic Acid; Catalase; Hordeum; Hydrogen Peroxide; Lipid Peroxidation; Malondialdehyde; Nanoparticles; Oxidation-Reduction; Oxidative Stress; Plant Leaves; Plant Roots; Reactive Oxygen Species; Silicon Dioxide; Superoxide Dismutase | 2018 |
NF-κB and AMPK/PI3K/Akt signaling pathways are involved in the protective effects of Platycodon grandiflorum saponins against acetaminophen-induced acute hepatotoxicity in mice.
Topics: Acetaminophen; Aldehydes; AMP-Activated Protein Kinases; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Glutathione; Interleukin-1beta; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; NF-kappa B; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphorylation; Plant Roots; Platycodon; Proto-Oncogene Proteins c-akt; Saponins; Signal Transduction; Tumor Necrosis Factor-alpha | 2018 |
Augmenter of Liver Regeneration Protects Against Acetaminophen-Induced Acute Liver Injury in Mice by Promoting Autophagy.
Topics: Acetaminophen; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Autophagy; Chemical and Drug Induced Liver Injury; Female; Liver; Liver Regeneration; Malondialdehyde; Mice; Mice, Inbred BALB C; Oxidative Stress | 2019 |
Platycodin D protects acetaminophen-induced hepatotoxicity by inhibiting hepatocyte MAPK pathway and apoptosis in C57BL/6J mice.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Apoptosis; Chemical and Drug Induced Liver Injury; Glutathione; Hepatocytes; Inflammation; Liver; Male; Malondialdehyde; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Oxidative Stress; Platycodon; Protective Agents; Saponins; Triterpenes | 2018 |
Protective effects of extracts of Schisandra chinensis stems against acetaminophen-induced hepatotoxicity via regulation of MAPK and caspase-3 signaling pathways.
Topics: Acetaminophen; Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Caspase 3; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Glutathione; Humans; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; Oxidative Stress; Schisandra; Signal Transduction | 2018 |
Effect of Ocimum basilicum leaves extract on acetaminophen-induced nephrotoxicity in BALB/c mice.
Topics: Acetaminophen; Acute Kidney Injury; Animals; Aspartate Aminotransferases; Catalase; Humans; Kidney; Liver; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Ocimum basilicum; Oxidative Stress; Plant Extracts; Plant Leaves; Superoxide Dismutase | 2018 |
Polydatin protects against acetaminophen-induced hepatotoxicity in mice via anti-oxidative and anti-apoptotic activities.
Topics: Acetaminophen; Alanine Transaminase; Animals; Antioxidants; Apoptosis; Apoptotic Protease-Activating Factor 1; Aspartate Aminotransferases; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Chemical and Drug Induced Liver Injury; Glucosides; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Hepatocytes; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; NADPH Oxidase 2; Nitric Oxide Synthase Type II; Oxidative Stress; Protective Agents; Reactive Oxygen Species; Stilbenes | 2018 |
Improved protective effects of American ginseng berry against acetaminophen-induced liver toxicity through TNF-α-mediated caspase-3/-8/-9 signaling pathways.
Topics: Acetaminophen; Alanine Transaminase; Aldehydes; Animals; Aspartate Aminotransferases; Caspases; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Fruit; Glutathione; Interleukin-1beta; Liver; Male; Malondialdehyde; Mice; Necrosis; Oxidative Stress; Panax; Plant Extracts; Signal Transduction; Superoxide Dismutase; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2018 |
[Protective effect of Ginkgo biloba extract on paracetamol-induced acute hepatic injury in mice].
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Ginkgo biloba; Liver; Malondialdehyde; Mice; Oxidative Stress; Plant Extracts | 2018 |
Effect of carvedilol versus propranolol on acute and chronic liver toxicity in rats.
Topics: Acetaminophen; Adrenergic beta-Antagonists; Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Carbon Tetrachloride; Carvedilol; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Glutathione; Hepatic Stellate Cells; Liver; Liver Cirrhosis, Experimental; Male; Malondialdehyde; Oxidative Stress; Propranolol; Rats, Wistar; Tumor Necrosis Factor-alpha | 2021 |
Thymoquinone and curcumin modify inducible nitric oxide synthase, caspase 3, and thioredoxin immunohistochemical expression in acetaminophen hepatotoxicity.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Benzoquinones; Bilirubin; Caspase 3; Curcumin; Glutathione; Immunohistochemistry; Liver; Liver Diseases; Male; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Superoxide Dismutase; Thioredoxins | 2019 |
The protective efficacy of soursop fruit extract against hepatic injury associated with acetaminophen exposure is mediated through antioxidant, anti-inflammatory, and anti-apoptotic activities.
Topics: Acetaminophen; Alanine Transaminase; Animals; Annona; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Aspartate Aminotransferases; Catalase; Fruit; Glutathione; Liver; Malondialdehyde; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Vegetables | 2019 |
Allyl methyl trisulfide protected against acetaminophen (paracetamol)-induced hepatotoxicity by suppressing CYP2E1 and activating Nrf2 in mouse liver.
Topics: Acetaminophen; Alanine Transaminase; Allyl Compounds; Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Glutathione; Liver; Male; Malondialdehyde; Mice; NF-E2-Related Factor 2; Oxidative Stress; Protective Agents; Sulfides; Superoxide Dismutase | 2019 |
Geniposide protected hepatocytes from acetaminophen hepatotoxicity by down-regulating CYP 2E1 expression and inhibiting TLR 4/NF-κB signaling pathway.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Down-Regulation; Glutathione; Hepatocytes; Interleukin-1beta; Iridoids; Liver; Macrophages; Male; Malondialdehyde; Mice, Inbred C57BL; Neutrophils; NF-kappa B; Protective Agents; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2019 |
Schisandra chinensis acidic polysaccharide partialy reverses acetaminophen-induced liver injury in mice.
Topics: Acetaminophen; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Caspase 3; Chemical and Drug Induced Liver Injury; Glutathione; Glycogen Synthase Kinase 3 beta; Heme Oxygenase-1; Interleukin-1beta; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; NF-E2-Related Factor 2; Oxidative Stress; Plant Extracts; Polysaccharides; Proto-Oncogene Proteins c-bcl-2; Schisandra; Superoxide Dismutase | 2019 |
Microsomal prostaglandin E synthase 2 deficiency is resistant to acetaminophen-induced liver injury.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Cysteine; Dinoprostone; Glutathione; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Mice, Knockout; Prostaglandin-E Synthases | 2019 |
Acetaminophen sensitizing erastin-induced ferroptosis via modulation of Nrf2/heme oxygenase-1 signaling pathway in non-small-cell lung cancer.
Topics: Acetaminophen; Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Drug Synergism; Ferroptosis; Gene Expression Regulation, Neoplastic; Heme Oxygenase-1; Humans; Lipid Peroxides; Malondialdehyde; Mice; NF-E2-Related Factor 2; Oleanolic Acid; Piperazines; Signal Transduction; Xenograft Model Antitumor Assays | 2020 |
Nobiletin attenuates acetaminophen-induced hepatorenal toxicity in rats.
Topics: Acetaminophen; Alanine Transaminase; Animals; Anti-Inflammatory Agents; Antioxidants; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Creatinine; Cytokines; Flavones; Glutathione; Glutathione Peroxidase; Heme Oxygenase (Decyclizing); Kidney; Liver; Male; Malondialdehyde; NF-E2-Related Factor 2; Oxidative Stress; Rats; Rats, Wistar; Urea | 2020 |
Upregulation of Nrf2-related cytoprotective genes expression by acetaminophen-induced acute hepatotoxicity in mice and the protective role of betaine.
Topics: Acetaminophen; Alanine Transaminase; Analgesics; Animals; Aspartate Aminotransferases; Betaine; Chemical and Drug Induced Liver Injury; Gene Expression; Glutathione; Heme Oxygenase-1; Liver; Male; Malondialdehyde; Membrane Proteins; Mice; NF-E2-Related Factor 2; Protective Agents; Up-Regulation | 2020 |
[Study on protective effect of water extract from Sabia parviflora on liver injury in mice induced by acetaminophen].
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Liver; Malondialdehyde; Mice; Oxidative Stress; Plant Extracts; Superoxide Dismutase | 2020 |
Kaempferol from
Topics: Acetaminophen; Alanine Transaminase; Animals; Antioxidants; Apoptosis; Chemical and Drug Induced Liver Injury; Glutathione; Hepatocytes; HMGB1 Protein; Inflammasomes; Interleukin-1beta; Kaempferols; Liver; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; RNA, Messenger; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2020 |
Hepatoprotective effect of Omega-3 PUFAs against acute paracetamol-induced hepatic injury confirmed by FTIR.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cholesterol; Fatty Acids, Omega-3; Female; Glutathione; Hepatocytes; Interleukin-6; Liver; Malondialdehyde; Nitric Oxide; Protective Agents; Rats, Wistar; Spectroscopy, Fourier Transform Infrared; Tumor Necrosis Factor-alpha | 2021 |
Comparison of ameliorative effects of Taraxacum syriacum and N-acetylcysteine against acetaminophen-induced oxidative stress in rat liver and kidney.
Topics: Acetaminophen; Acetylcysteine; Animals; Antioxidants; Catalase; Chemical and Drug Induced Liver Injury; Ethanol; Free Radical Scavengers; Glutathione; Humans; Kidney; Lipid Peroxidation; Liver; Male; Malondialdehyde; Oxidative Stress; Plant Extracts; Rats; Rats, Wistar; Superoxide Dismutase; Taraxacum | 2021 |
Dibenzazepine combats acute liver injury in rats via amendments of Notch signaling and activation of autophagy.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Autophagy; Chemical and Drug Induced Liver Injury; Dibenzazepines; Interleukin-6; Liver; Male; Malondialdehyde; NF-kappa B; Nitric Oxide; Oxidative Stress; Protective Agents; Rats, Sprague-Dawley; Receptor, Notch1; Signal Transduction; Transcription Factor HES-1; Tumor Necrosis Factor-alpha | 2021 |
Protective Effect of Dihydrokaempferol on Acetaminophen-Induced Liver Injury by Activating the SIRT1 Pathway.
Topics: Acetaminophen; Alanine Transaminase; Anti-Inflammatory Agents; Antioxidants; Aspartate Aminotransferases; Autophagy; Cells, Cultured; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Flavonoids; Gene Expression; Humans; Malondialdehyde; NF-E2-Related Factor 2; Oxidative Stress; Phytotherapy; Reactive Oxygen Species; Signal Transduction; Sirtuin 1 | 2021 |
Can granulocyte colony stimulating factor (G-CSF) ameliorate acetaminophen-induced hepatotoxicity?
Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Alkaline Phosphatase; Analgesics, Non-Narcotic; Animals; Aspartate Aminotransferases; Catalase; Chemical and Drug Induced Liver Injury; Female; Free Radical Scavengers; Gene Expression Regulation; Granulocyte Colony-Stimulating Factor; L-Lactate Dehydrogenase; Malondialdehyde; Nitric Oxide; Rats; Rats, Wistar | 2021 |
Sage,
Topics: Acetaminophen; Animals; Antineoplastic Agents, Phytogenic; Gas Chromatography-Mass Spectrometry; HeLa Cells; Hep G2 Cells; Humans; Liver; Male; Malondialdehyde; MCF-7 Cells; Oils, Volatile; Plant Oils; Rats; Rats, Wistar; Salvia officinalis | 2021 |
Echinacoside alleviates acetaminophen-induced liver injury by attenuating oxidative stress and inflammatory cytokines in mice.
Topics: Acetaminophen; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Cytochrome P-450 CYP2E1; Cytokines; Glycosides; Interleukin-1beta; Interleukin-6; Malondialdehyde; Mice; Molecular Docking Simulation; Oxidative Stress; Sulfotransferases; Tumor Necrosis Factor-alpha; Uridine Diphosphate | 2021 |
The protective effect of carvacrol on acetaminophen-induced renal damage in male rats.
Topics: Acetaminophen; Animals; Apoptosis; Cymenes; Kidney; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase | 2022 |
Ameliorative effect of Spatoglossum asperum and its solvent fractions against acetaminophen-induced liver dysfunction in rats.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Antioxidants; Biomarkers; Caspase 3; Chemical and Drug Induced Liver Injury; Chemical Fractionation; Female; Gene Expression Regulation; Glutathione; Interleukin-6; Liver; Malondialdehyde; Nitric Oxide; Rats; Rats, Wistar; Seaweed | 2022 |
[Preparation of salvianolic acid B, tanshinone Ⅱ_A, and glycyrrhetinic acid lipid emulsion and its protective effect against acute liver injury induced by acetaminophen].
Topics: Abietanes; Acetaminophen; Alanine Transaminase; Animals; Antipyretics; Aspartate Aminotransferases; Benzofurans; Chemical and Drug Induced Liver Injury; Depsides; Emulsions; Glycyrrhetinic Acid; Liver; Malondialdehyde; Mice | 2022 |
Caesalpinia bonducella Counteracts Paracetamol-Instigated Hepatic Toxicity via Modulating TNF-α and IL-6/10 Expression and Bcl-2 and Caspase-8/3 Signalling.
Topics: Acetaminophen; Animals; Antioxidants; Caesalpinia; Caspase 3; Caspase 8; Chemical and Drug Induced Liver Injury; Cytokines; Female; Interleukin-10; Interleukin-6; Liver; Malondialdehyde; Oxidative Stress; Rats; Tumor Necrosis Factor-alpha | 2023 |