acetaminophen has been researched along with lignans in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.00) | 18.7374 |
| 1990's | 2 (10.00) | 18.2507 |
| 2000's | 2 (10.00) | 29.6817 |
| 2010's | 9 (45.00) | 24.3611 |
| 2020's | 6 (30.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, GT | 1 |
| Liu, GT; Wei, HL | 1 |
| Kawasaki, H; Murawaki, Y; Yamada, S | 1 |
| Bachleda, P; Dvorák, Z; Kosina, P; Simánek, V; Ulrichová, J; Walterová, D | 1 |
| Chang, YC; Chen, YH; Chiu, JH; Ho, YY; Hong, CY; Huang, YT; Lai, MT; Lin, FY; Liu, PL; Man, KM | 1 |
| Hwang, SJ; Kay, HY; Kim, SG; Kim, YW; Ryu, DH; Sung, SH | 1 |
| Chen, Y; Li, L; Xin, Y; Xing, G; Zhang, T; Zhou, L | 1 |
| Bi, H; Chen, P; Fan, X; Gonzalez, FJ; Huang, M; Jiang, Y; Tan, H; Wang, Y; Zeng, H | 1 |
| Guo, L; He, CJ; He, YC; Liu, JL; Peng, C; Xie, XF; Xiong, L; Zou, Y | 1 |
| Bi, H; Chen, P; Fan, X; Huang, M; Jiang, Y; Tan, H; Wang, Y; Zeng, H | 1 |
| Bi, H; Chen, P; Chen, Y; Fan, X; Huang, M; Jiang, Y; Li, D; Li, X; Qin, X; Tan, H; Wang, Y; Zeng, H; Zeng, X; Zhou, Y | 1 |
| Bi, HC; Chen, P; Fan, XM; Huang, M; Jiang, YM; Tan, HS; Wang, Y; Yu, T; Zeng, H | 1 |
| Chen, MH; Li, R; Li, YC; Lin, S; Liu, W; Qu, YH; Sun, H; Wang, LY; Wang, SJ; Wu, J; Wu, YZ; Zhang, D | 1 |
| Wu, JW; Yu, FL; Zhu, H | 1 |
| Li, S; Qi, XZ; Shao, SY; Sun, H | 1 |
| Ding, Q; Du, Y; Guo, H; Hu, K; Huang, H; Kang, D; Li, C; Liang, Y; Shao, Y; Wang, G; Wang, H; Xie, L; Yan, C; Yu, T | 1 |
| Cao, L; Cheng, S; Iqbal Choudhary, M; Jia, Y; Jian, Y; Li, B; Liu, Y; Peng, C; Rahman, AU; Wang, W; Yang, Y; Yu, H | 1 |
| Deng, S; Ge, J; Li, J; Li, M; Li, X; Ma, L; Ma, Y; Zhang, J; Zheng, Y | 1 |
| Cao, Y; Cheng, L; Gao, Z; Wang, L; Wang, T; Wu, W; Zhang, Q | 1 |
| Gao, GC; Gao, JL; Li, C; Lin, QY; Liu, SH; Ru, YJ; Wang, L; Wu, JM; Yang, YD; Zhang, XQ; Zheng, CW; Zheng, YX | 1 |
1 review(s) available for acetaminophen and lignans
| Article | Year |
|---|---|
Effects of some compounds isolated from Chinese medicinal herbs on hepatic microsomal cytochrome P-450 and their potential biological consequences.
Topics: Acetaminophen; Alkaloids; Animals; Carbon Tetrachloride; Carcinogens; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drugs, Chinese Herbal; Enzyme Induction; Humans; Isoquinolines; Lignans; Lignin; Liver | 1991 |
19 other study(ies) available for acetaminophen and lignans
| Article | Year |
|---|---|
[Protection by fructus Schizandrae against acetaminophen hepatotoxicity in mice].
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cyclooctanes; Dioxoles; Drugs, Chinese Herbal; Glutathione; Lignans; Liver; Male; Mice; Microsomes, Liver; Polycyclic Compounds | 1987 |
Preventive effect of gomisin A, a lignan component of shizandra fruits, on acetaminophen-induced hepatotoxicity in rats.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cyclooctanes; Dioxoles; Drugs, Chinese Herbal; Glutathione; Lignans; Lipid Peroxides; Liver; Liver Diseases; Male; Organ Size; Rats; Rats, Wistar; Time Factors | 1993 |
Primary cultures of human hepatocytes as a tool in cytotoxicity studies: cell protection against model toxins by flavonolignans obtained from Silybum marianum.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Antioxidants; Asteraceae; Biphenyl Compounds; Cell Separation; Cell Survival; Cells, Cultured; Flavonoids; Free Radical Scavengers; Galactosamine; Hepatocytes; Humans; L-Lactate Dehydrogenase; Lignans; Picrates; Plant Extracts; Propanols; Protein Biosynthesis; tert-Butylhydroperoxide; Toxins, Biological | 2003 |
Antioxidative and hepatoprotective effects of magnolol on acetaminophen-induced liver damage in rats.
Topics: Acetaminophen; Animals; Antioxidants; Biphenyl Compounds; Glutathione; Lignans; Lipid Peroxidation; Liver; Liver Failure, Acute; Magnolia; Male; Rats; Rats, Sprague-Dawley | 2009 |
Nrf2-mediated liver protection by sauchinone, an antioxidant lignan, from acetaminophen toxicity through the PKCδ-GSK3β pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Antioxidants; Benzopyrans; Dioxoles; Glutathione; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hep G2 Cells; Humans; Lignans; Liver; Major Histocompatibility Complex; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Phytotherapy; Plant Preparations; Protective Agents; Protein Kinase C-delta; Proteins; Saururaceae; Signal Transduction; Vesicular Transport Proteins | 2011 |
Schisandrin B attenuates acetaminophen-induced hepatic injury through heat-shock protein 27 and 70 in mice.
Topics: Acetaminophen; Administration, Oral; Animals; Chemical and Drug Induced Liver Injury; Cyclooctanes; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression; HSP27 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Lignans; Liver; Male; Mice; Phytotherapy; Polycyclic Compounds; Schisandra; Time Factors | 2014 |
Schisandrol B protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of liver regeneration.
Topics: Acetaminophen; Activation, Metabolic; Animals; Apoptosis Regulatory Proteins; Benzoquinones; Binding Sites; Biomarkers; Catalytic Domain; Chemical and Drug Induced Liver Injury; Cyclooctanes; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Cytoprotection; Dioxoles; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Glutathione; Imines; Lignans; Liver; Liver Regeneration; Male; Membrane Proteins; Mice, Inbred C57BL; Mitochondria, Liver; Molecular Docking Simulation; Protein Binding; Protein Conformation; Signal Transduction | 2015 |
Penthorin A and B, two unusual 2,4'-epoxy-8,5'-neolignans from Penthorum chinese.
Topics: Acetaminophen; Cell Line; Hepatocytes; Humans; Lignans; Molecular Structure; Saxifragaceae | 2015 |
Hepato-protective effects of six schisandra lignans on acetaminophen-induced liver injury are partially associated with the inhibition of CYP-mediated bioactivation.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Cyclooctanes; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Dioxoles; Lignans; Liver; Male; Membrane Proteins; Mice, Inbred C57BL; Polycyclic Compounds; Protective Agents; Schisandra | 2015 |
Hepatoprotective Effects of Schisandra sphenanthera Extract against Lithocholic Acid-Induced Cholestasis in Male Mice Are Associated with Activation of the Pregnane X Receptor Pathway and Promotion of Liver Regeneration.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cholestasis; Cytochrome P-450 CYP3A; Drugs, Chinese Herbal; Glucuronosyltransferase; Lignans; Lithocholic Acid; Liver; Liver Regeneration; Male; Mice; Mice, Inbred C57BL; Plant Extracts; Pregnane X Receptor; Protective Agents; Receptors, Steroid; Schisandra; Signal Transduction | 2016 |
Schisandrol B protects against acetaminophen-induced acute hepatotoxicity in mice via activation of the NRF2/ARE signaling pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Antioxidant Response Elements; Chemical and Drug Induced Liver Injury; Cyclooctanes; Dioxoles; Gene Expression Regulation; Hep G2 Cells; Humans; Lignans; Liver; Male; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Protective Agents; RNA, Messenger; Schisandra; Signal Transduction | 2016 |
Bioactive Glycosides from the Twigs of Litsea cubeba.
Topics: Acetaminophen; Algorithms; Crystallography, X-Ray; Drugs, Chinese Herbal; Glycosides; Hep G2 Cells; Humans; Inhibitory Concentration 50; Lignans; Lipopolysaccharides; Litsea; Molecular Conformation; Molecular Structure; Nitric Oxide; Nuclear Magnetic Resonance, Biomolecular; Plant Roots; Plant Stems | 2017 |
Honokiol alleviates acetaminophen-induced hepatotoxicity via decreasing generation of acetaminophen-protein adducts in liver.
Topics: Acetaminophen; Animals; Biphenyl Compounds; Chemical and Drug Induced Liver Injury; Glutathione; Lignans; Liver; Male; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2; Oxidative Stress; Protective Agents; Signal Transduction | 2019 |
Hepatoprotective lignans and triterpenoids from the roots of Kadsura longipedunculata.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Hep G2 Cells; Hepatocytes; Humans; Kadsura; Lignans; Molecular Structure; Plant Roots; Triterpenes | 2020 |
Multiomics Profiling Reveals Protective Function of
Topics: Acetaminophen; Administration, Oral; Animals; Cells, Cultured; Chemical and Drug Induced Liver Injury; Diglycerides; Disease Models, Animal; Drugs, Chinese Herbal; Hepatocytes; Humans; Lignans; Lipid Metabolism; Lipidomics; Liver; Male; Mice; Primary Cell Culture; Protective Agents; Protein Kinase C; Proteomics; Schisandra; Triglycerides | 2020 |
Dibenzocyclooctadiene lignans from Kadsura coccinea alleviate APAP-induced hepatotoxicity via oxidative stress inhibition and activating the Nrf2 pathway in vitro.
Topics: Acetaminophen; Cell Survival; Cyclooctanes; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Kadsura; Lignans; Molecular Structure; NF-E2-Related Factor 2; Oxidative Stress; Protective Agents; Structure-Activity Relationship | 2021 |
Network pharmacology, molecular docking technology integrated with pharmacodynamic study to reveal the potential targets of Schisandrol A in drug-induced liver injury by acetaminophen.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cyclooctanes; Dose-Response Relationship, Drug; Lignans; Male; Mice; Mice, Inbred ICR; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship | 2022 |
Study on the Protective Effect of Schizandrin B against Acetaminophen-Induced Cytotoxicity in Human Hepatocyte.
Topics: Acetaminophen; Apoptosis Regulatory Proteins; Chemical and Drug Induced Liver Injury; Cyclooctanes; Hepatocytes; Humans; Lignans; Mitogen-Activated Protein Kinase Kinases; Polycyclic Compounds | 2022 |
Schisantherin D from Schisandra chinensis (Turcz.) Baill. exhibits anti-liver fibrosis capacity via modulating ETBR involved signaling, an in vitro and in vivo study.
Topics: Acetaminophen; Aflatoxin B1; Animals; Dioxoles; Humans; Lignans; Liver Cirrhosis; Mice; Molecular Structure; NF-E2-Related Factor 2; Receptor, Endothelin B; Schisandra; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2022 |