acetaminophen has been researched along with hydrogen in 74 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.35) | 18.7374 |
| 1990's | 8 (10.81) | 18.2507 |
| 2000's | 17 (22.97) | 29.6817 |
| 2010's | 43 (58.11) | 24.3611 |
| 2020's | 5 (6.76) | 2.80 |
| Authors | Studies |
|---|---|
| Kayama, H; Koh, K | 1 |
| Kölbel, CB; Layer, P | 1 |
| Hogan, DL; Isenberg, JI; Stern, AI | 1 |
| Hammas, B; Hvarfner, A; Thörn, SE; Wattwil, M | 1 |
| Augsburger, L; Habib, Y; Reier, G; Shangraw, R; Wheatley, T | 1 |
| Baede, EJ; Bessems, JG; de Groot, MJ; te Koppele, JM; Vermeulen, NP | 1 |
| Levein, NG; Thörn, SE; Wattwil, M | 1 |
| Aydin, I; Murray, M; Sakr, A; Turkoglu, M | 1 |
| Railkar, AM; Schwartz, JB | 1 |
| Ho, H; Ke, W; Sheu, M; Tsai, T | 1 |
| Cole, SM; Jones, JG; Malloy, CR; Sherry, AD; Solomon, MA | 1 |
| Edge, S; Kaerger, JS; Price, R | 1 |
| Iloañusi, NO; Schwartz, JB | 1 |
| Gupta, A; Miller, RW; Morris, KR; Peck, GE | 2 |
| Kleinebudde, P; Thommes, M | 2 |
| Briscoe, BJ; Mohammed, H; Pitt, KG | 1 |
| Burt, HM; Miller, RA; Zhao, J | 1 |
| Okor, RS; Uhumwangho, MU | 1 |
| Charoenthai, N; Kleinebudde, P; Puttipipatkhachorn, S | 1 |
| Ahonen, A; Kanerva, H; Lindevall, K; Marvola, J; Marvola, M; Marvola, T | 1 |
| Carvajal, MT; Feng, T; Pinal, R; Wang, F; Wassgren, C | 1 |
| Foppoli, A; Gazzaniga, A; Maroni, A; Palugan, L; Sangalli, ME; Zema, L | 1 |
| Lalwani, AN; Parikh, JR | 1 |
| Cosijns, A; De Beer, T; Evrard, B; Nikolakakis, I; Nizet, D; Remon, JP; Siepmann, F; Siepmann, J; Vervaet, C | 1 |
| Attama, AA; Bonaventure, AM; Builders, PF; Okpako, LC; Tiwalade, A | 1 |
| Bansal, AK; Kaushal, AM; Patel, S | 1 |
| Hatara, J; Heinämäki, J; Seppälä, K; Seppälä, L; Yliruusi, J | 1 |
| de Villiers, MM; Liebenberg, W; Lvov, YM; Otto, DP; Strydom, SJ | 1 |
| Cuitino, A; Lewis, D; Mendez, R; Michniak-Kohn, B; Muzzio, F; Pingali, K | 1 |
| Griesbacher, M; Khinast, J; Radl, S; Roblegg, E; Schrank, S; Zimmer, A | 1 |
| Abdel-Hamid, S; Alshihabi, F; Betz, G | 1 |
| Hirvonen, J; Kolakovic, R; Laaksonen, T; Laukkanen, A; Peltonen, L; Putkisto, K | 1 |
| Alshihabi, F; Betz, G; Vandamme, T | 1 |
| Casettari, L; Castagnino, E; Cespi, M | 1 |
| Koester, M; Thommes, M | 1 |
| Llusá, M; Muzzio, FJ; Pingali, K | 1 |
| Koester, M; Krueger, C; Thommes, M; Willemsen, E | 1 |
| Betz, G; Martínez, L; Melgoza, L; Villalobos, R; Young, PM | 1 |
| Kuentz, M; Nalluri, VR; Puchkov, M | 1 |
| Hakulinen, M; Ketolainen, J; Leskinen, JT; Simonaho, SP | 1 |
| Järvinen, K; Järvinen, MA; Juuti, M; Leiviskä, K; Muzzio, F; Paaso, J; Paavola, M | 1 |
| Anderson, CA; Bondi, RW; Drennen, JK; Igne, B | 1 |
| Li, L; Mao, S; Ni, R; Shao, Y; Wang, L; Zhang, T | 1 |
| Muzzio, FJ; Osorio, JG | 1 |
| Kim, JW; Kim, KB; Kim, S; Lee, HW; Lim, MS; Ryu, SH; Seong, SJ; Yoon, YR | 1 |
| Anderson, CA; de Juan, A; Drennen, JK; Igne, B; Jaumot, J | 1 |
| Heng, PW; Liew, CV; Loh, ZH; Soh, JL; Tan, BM | 1 |
| Kašpar, O; Oka, S; Ramachandran, R; Sowrirajan, K; Štěpánek, F; Tokárová, V | 1 |
| Alles, R; Atria, S; Gane, PA; Huwyler, J; Puchkov, M; Schoelkopf, J; Stirnimann, T | 1 |
| Anderson, CA; de Juan, A; Drennen, JK; Igne, B; Jaumot, J; Lallemand, J; Preys, S | 1 |
| Awa, K; Ozaki, Y; Shinzawa, H | 1 |
| Aoki, H; Ishida, M; Itai, S; Iwao, Y; Kajihara, R; Noguchi, S; Suzuki, Y; Takahashi, K; Terada, Y; Uchimoto, T | 1 |
| Jørgensen, FS; Leth, R; Olsen, L; Rydberg, P | 1 |
| Liu, C; Pang, Q; Song, SD; Wan, Y; Wu, QF; Yuan, DW; Zhang, JY; Zhang, RY | 1 |
| Kotamarthy, L; Litster, JD; Marc, M; Meng, W; Muzzio, FJ; Panikar, S; Pradhan, S; Ramachandran, R; Sen, M | 1 |
| Bezuijen, A; De Beer, T; De Jaeghere, W; Grymonpré, W; Remon, JP; Stauffer, F; Vanhoorne, V; Vercruysse, J; Verstraete, G; Vervaet, C | 1 |
| DeHart, M; Gupte, A; Haware, RV; Stagner, WC | 1 |
| Chiriac, AP; Creteanu, A; Diaconu, A; Dragostin, O; Mititelu-Tartau, L; Nita, LE; Popa, G; Rusu, D; Tudorachi, N | 1 |
| Hayashi, Y; Hirai, D; Kosugi, A; Kumada, S; Oishi, T; Onuki, Y; Shirotori, K; Takayama, K; Tsuji, T | 1 |
| Ganesh, S; Lim, J; Nagy, Z; Reklaitis, G; Schmall, N; Troscinski, R | 1 |
| Abrahmsén-Alami, S; Ervasti, T; Folestad, S; Fransson, M; Karttunen, AP; Ketolainen, J; Korhonen, O; Lakio, S; Tajarobi, P; Wikström, H | 1 |
| Escotet-Espinoza, MS; Ierapetritou, MG; Muzzio, FJ; Singh, R; Vadodaria, S | 1 |
| Chawla, N; Emady, HN; Gao, T; Oka, S; Ramachandran, R; Singaravelu, ASS; Štepánek, F | 1 |
| Anderson, CA; Drennen, JK; Hossain, MN; Igne, B | 1 |
| Abrahmsén-Alami, S; Folestad, S; Fransson, M; Karttunen, AP; Ketolainen, J; Korhonen, O; Marucci, M; Sparén, A; Tajarobi, P; Wikström, H | 1 |
| Prusnick, T; Šašić, S | 1 |
| Emady, HN; Li, C; Zhang, L; Zhu, N | 1 |
| Kushida, K; Matsuda, Y; Nakamura, H; Ohsaki, S; Watano, S | 1 |
| Heinrich, T; Kalies, A; Leopold, CS | 1 |
| Al-Sharabi, M; Bawuah, P; Gane, P; Karttunen, AP; Ketolainen, J; Markl, D; Mudley, T; Peiponen, KE; Rades, T; Ridgway, C; Zeitler, JA | 1 |
| Hafizi, H; Marjani, A; Pishnamazi, M; Shirazian, S; Walker, GM | 1 |
| Bathaie, SZ; Hashemi, SA; Kyani, A | 1 |
1 review(s) available for acetaminophen and hydrogen
| Article | Year |
|---|---|
[The diagnosis in motility disorders of the stomach and small intestine].
Topics: Acetaminophen; Breath Tests; Electrophysiology; Gastrointestinal Motility; Humans; Hydrogen; Intestinal Diseases; Intestine, Small; Manometry; Radiography; Radionuclide Imaging; Sodium Chloride; Stomach; Stomach Diseases; Ultrasonography | 1991 |
3 trial(s) available for acetaminophen and hydrogen
| Article | Year |
|---|---|
Propofol sedation and gastric emptying in volunteers.
Topics: Absorption; Acetaminophen; Adult; Analgesics, Non-Narcotic; Area Under Curve; Gastric Emptying; Gastrointestinal Transit; Humans; Hydrogen; Hypnotics and Sedatives; Infusions, Intravenous; Male; Placebos; Propofol; Raffinose; Sodium Chloride; Time Factors | 1998 |
Dopamine delays gastric emptying and prolongs orocaecal transit time in volunteers.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Area Under Curve; Breath Tests; Cecum; Dopamine; Gastric Emptying; Gastrointestinal Agents; Gastrointestinal Motility; Gastrointestinal Transit; Humans; Hydrogen; Infusions, Intravenous; Intestinal Absorption; Male; Placebos; Stomach | 1999 |
Pattern recognition analysis for hepatotoxicity induced by acetaminophen using plasma and urinary 1H NMR-based metabolomics in humans.
Topics: Acetaminophen; Adult; Biomarkers; Chemical and Drug Induced Liver Injury; Humans; Hydrogen; Magnetic Resonance Spectroscopy; Male; Metabolomics; Middle Aged; Pattern Recognition, Automated; Republic of Korea; Young Adult | 2013 |
70 other study(ies) available for acetaminophen and hydrogen
| Article | Year |
|---|---|
[Clinical and experimental studies on gastrointestinal motility following total colectomy: direct measurement (strain gauge force transducer method, barium method) and indirect measurement (hydrogen breath test, acetaminophen method)].
Topics: Acetaminophen; Adolescent; Adult; Animals; Breath Tests; Colectomy; Colonic Diseases; Dogs; Female; Gastric Emptying; Gastrointestinal Motility; Humans; Hydrogen; Ileum; Male; Middle Aged; Monitoring, Physiologic; Time Factors; Transducers | 1991 |
A new method for quantitation of ion fluxes across in vivo human gastric mucosa: effect of aspirin, acetaminophen, ethanol, and hyperosmolar solutions.
Topics: Acetaminophen; Adult; Aspirin; Chlorides; Endoscopy; Ethanol; Female; Gastric Mucosa; Humans; Hydrogen; Hypertonic Solutions; Ion Channels; Male; Membrane Potentials; Middle Aged; Osmolar Concentration; Potassium; Sodium | 1984 |
Dilution potential: a new perspective.
Topics: Acetaminophen; Area Under Curve; Cellulose; Indicator Dilution Techniques; Powders; Tablets; Tensile Strength | 1996 |
Hydrogen atom abstraction of 3,5-disubstituted analogues of paracetamol by horseradish peroxidase and cytochrome P450.
Topics: Acetaminophen; Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Free Radicals; Horseradish Peroxidase; Hydrogen; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Rats; Rats, Wistar; Thermodynamics | 1998 |
Modeling of a roller-compaction process using neural networks and genetic algorithms.
Topics: Acetaminophen; Acrylic Resins; Algorithms; Analgesics, Non-Narcotic; Cellulose; Chemistry, Pharmaceutical; Compressive Strength; Elasticity; Excipients; Hypromellose Derivatives; Methylcellulose; Models, Chemical; Models, Genetic; Neural Networks, Computer; Polyethylene Glycols; Polyvinyls; Predictive Value of Tests; Tablets | 1999 |
Evaluation and comparison of a moist granulation technique to conventional methods.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Cellulose; Chemistry, Pharmaceutical; Delayed-Action Preparations; Excipients; Particle Size; Pharmaceutic Aids; Povidone; Tablets | 2000 |
Sustained-release effect of codried excipients of microcrystalline cellulose and Ganoderma fiber.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Cellulose; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drugs, Chinese Herbal; Excipients; Microscopy, Electron, Scanning; Reishi; Solubility; Time Factors | 2001 |
An integrated (2)H and (13)C NMR study of gluconeogenesis and TCA cycle flux in humans.
Topics: Acetaminophen; Adult; Blood Glucose; Carbon Isotopes; Citric Acid Cycle; Deuterium; Female; Gluconeogenesis; Glucose; Glutamine; Humans; Hydrogen; Kinetics; Liver; Liver Glycogen; Magnetic Resonance Spectroscopy; Male; Models, Biological; Phosphoenolpyruvate; Propionates; Reference Values; Time Factors; Water | 2001 |
Influence of particle size and shape on flowability and compactibility of binary mixtures of paracetamol and microcrystalline cellulose.
Topics: Acetaminophen; Cellulose; Chemistry, Pharmaceutical; Compressive Strength; Particle Size | 2004 |
The effect of wax on compaction of microcrystalline cellulose beads made by extrusion and spheronization.
Topics: Acetaminophen; Cellulose; Chemistry, Pharmaceutical; Compressive Strength; Drug Compounding; Drug Stability; Excipients; Fatty Acids; Particle Size; Porosity; Pressure | 1998 |
Real-time near-infrared monitoring of content uniformity, moisture content, compact density, tensile strength, and Young's modulus of roller compacted powder blends.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analysis of Variance; Cellulose; Drug Compounding; Humidity; Powders; Pressure; Spectroscopy, Near-Infrared; Tablets; Tensile Strength | 2005 |
Effect of the variation in the ambient moisture on the compaction behavior of powder undergoing roller-compaction and on the characteristics of tablets produced from the post-milled granules.
Topics: Acetaminophen; Cellulose; Drug Compounding; Excipients; Humidity; Particle Size; Porosity; Powders; Solubility; Tablets; Tensile Strength; Water | 2005 |
Use of kappa-carrageenan as alternative pelletisation aid to microcrystalline cellulose in extrusion/spheronisation. II. Influence of drug and filler type.
Topics: Acetaminophen; Carrageenan; Cellulose; Chemistry, Pharmaceutical; Drug Implants; Excipients; Mesalamine; Particle Size; Solubility; Surface Properties; Technology, Pharmaceutical; Tensile Strength; Theophylline; Water | 2006 |
A study on the coherence of compacted binary composites of microcrystalline cellulose and paracetamol.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Cellulose; Drug Compounding; Excipients; Models, Theoretical; Particle Size; Tablets; Tensile Strength | 2006 |
Use of kappa-carrageenan as alternative pelletisation aid to microcrystalline cellulose in extrusion/spheronisation. I. Influence of type and fraction of filler.
Topics: Acetaminophen; Carrageenan; Cellulose; Chemistry, Pharmaceutical; Drug Implants; Excipients; Particle Size; Porosity; Solubility; Surface Properties; Technology, Pharmaceutical; Tensile Strength; Water | 2006 |
The Gurnham equation in characterizing the compressibility of pharmaceutical materials.
Topics: Acetaminophen; Algorithms; Calcium Phosphates; Cellulose; Chemistry, Pharmaceutical; Compressive Strength; Drug Compounding; Excipients; Lactose; Pharmaceutical Preparations; Porosity; Powders; Pressure; Starch; Tablets | 2006 |
Studies on the compressibility of wax matrix granules of acetaminophen and their admixtures with various tableting bases.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Cellulose; Chemistry, Pharmaceutical; Excipients; Lactose; Rheology; Solubility; Tablets; Technology, Pharmaceutical; Tensile Strength; Time Factors; Waxes | 2006 |
Use of chitosan-alginate as alternative pelletization aid to microcrystalline cellulose in extrusion/spheronization.
Topics: Acetaminophen; Alginates; Cellulose; Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Chitosan; Drug Compounding; Excipients; Hardness; Image Processing, Computer-Assisted; Molecular Weight; Particle Size; Viscosity; Water | 2007 |
Neutron activation based gamma scintigraphic evaluation of enteric-coated capsules for local treatment in colon.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Biological Availability; Cellulose; Chemistry, Pharmaceutical; Colon; Drug Delivery Systems; Excipients; Gamma Rays; Humans; Hypromellose Derivatives; Male; Methylcellulose; Neutron Activation Analysis; Oxides; Polymethacrylic Acids; Radionuclide Imaging; Samarium; Solubility; Tablets, Enteric-Coated | 2008 |
Investigation of the variability of NIR in-line monitoring of roller compaction process by using Fast Fourier Transform (FFT) analysis.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Cellulose; Chemistry, Pharmaceutical; Computer Simulation; Equipment Design; Excipients; Models, Theoretical; Reproducibility of Results; Spectroscopy, Fourier Transform Infrared; Spectroscopy, Near-Infrared; Technology, Pharmaceutical; Time Factors | 2008 |
The use of beta-cyclodextrin in the manufacturing of disintegrating pellets with improved dissolution performances.
Topics: Acetaminophen; beta-Cyclodextrins; Cellulose; Chemistry, Pharmaceutical; Dosage Forms; Drug Compounding; Excipients; Ketoprofen; Kinetics; Models, Statistical; Solubility; Technology, Pharmaceutical | 2008 |
Preparation and evaluation of an ispaghula based directly compressible matrixing agent for controlled release.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Calcium Phosphates; Cellulose; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Compounding; Excipients; Hypromellose Derivatives; Kinetics; Lactose; Methylcellulose; Models, Chemical; Psyllium; Solubility; Tablets; Technology, Pharmaceutical | 2008 |
Porous pellets as drug delivery system.
Topics: Acetaminophen; Cellulose; Chemistry, Pharmaceutical; Drug Delivery Systems; Excipients; Ibuprofen; Metoprolol; Porosity; Sodium Chloride; Spectrum Analysis, Raman | 2009 |
Novel multifunctional pharmaceutical excipients derived from microcrystalline cellulose-starch microparticulate composites prepared by compatibilized reactive polymer blending.
Topics: Acetaminophen; Aspirin; Calorimetry, Differential Scanning; Cellulose; Chemistry, Pharmaceutical; Excipients; Freezing; Hardness; Microscopy, Electron, Scanning; Starch; Tablets; Temperature; Time Factors; Zea mays | 2010 |
Mechanistic investigation on pressure dependency of Heckel parameter.
Topics: Acetaminophen; Calcium Phosphates; Cellulose; Chemistry, Pharmaceutical; Elasticity; Excipients; Ibuprofen; Methylcellulose; Powders; Pressure; Sodium Chloride; Tablets; Technology, Pharmaceutical | 2010 |
Development of a new method to get a reliable powder flow characteristics using only 1 to 2 g of powder.
Topics: Acetaminophen; Cellulose; Excipients; Physical Phenomena; Physiological Phenomena; Powders | 2010 |
Preparation and characterization of directly compactible layer-by-layer nanocoated cellulose.
Topics: Acetaminophen; Cellulose; Chitosan; Drug Carriers; Feasibility Studies; Gelatin; Kinetics; Nanofibers; Nanotechnology; Particle Size; Polyethylenes; Polystyrenes; Povidone; Powders; Pressure; Quaternary Ammonium Compounds; Solubility; Surface Properties; Tablets; Technology, Pharmaceutical | 2011 |
Mixing order of glidant and lubricant--influence on powder and tablet properties.
Topics: Acetaminophen; Cellulose; Chemistry, Pharmaceutical; Excipients; Hardness; Hydrophobic and Hydrophilic Interactions; Lactose; Lubricants; Powders; Silicon Dioxide; Solubility; Stearic Acids; Tablets | 2011 |
Use of the direct compression aid Ludiflash(®) for the preparation of pellets via wet extrusion/spheronization.
Topics: Acetaminophen; Cellulose; Child; Compressive Strength; Delayed-Action Preparations; Excipients; Humans; Ibuprofen; Particle Size; Solubility; Tablets | 2011 |
Investigating the effect of particle size and shape on high speed tableting through radial die-wall pressure monitoring.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Cellulose; Drug Compounding; Elasticity; Excipients; Particle Size; Porosity; Povidone; Powders; Pressure; Surface Properties; Tablets; Tensile Strength | 2011 |
Spray-dried cellulose nanofibers as novel tablet excipient.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Cellulose; Chemistry, Pharmaceutical; Desiccation; Drug Compounding; Excipients; Kinetics; Microscopy, Electron, Scanning; Nanofibers; Porosity; Powders; Pressure; Rheology; Solubility; Surface Properties; Tablets; Technology, Pharmaceutical; Tensile Strength; Water | 2011 |
Focused beam reflectance method as an innovative (PAT) tool to monitor in-line granulation process in fluidized bed.
Topics: Acetaminophen; Cellulose; Dosage Forms; Drug Compounding; Drug Industry; Excipients; Particle Size; Povidone; Technology, Pharmaceutical | 2013 |
Evaluation of dibutyrylchitin as new excipient for sustained drug release.
Topics: Acetaminophen; Cellulose; Chemistry, Pharmaceutical; Chitin; Delayed-Action Preparations; Excipients; Hypromellose Derivatives; Lactose; Mesylates; Metformin; Methylcellulose; Pharmaceutical Preparations; Povidone; Starch; Tablets | 2012 |
Quantification of mass transfer during spheronisation.
Topics: Acetaminophen; Adhesiveness; Carrageenan; Cellulose; Chemistry, Pharmaceutical; Excipients; Ibuprofen; Models, Chemical; Particle Size; Powders; Technology, Pharmaceutical; Water | 2012 |
Method to study the effect of blend flowability on the homogeneity of acetaminophen.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Cellulose; Chemistry, Pharmaceutical; Excipients; Lubrication; Technology, Pharmaceutical | 2013 |
Systematic evaluations regarding interparticular mass transfer in spheronization.
Topics: Acetaminophen; Carrageenan; Cellulose; Drug Compounding; Excipients | 2012 |
Correlation between compactibility values and excipient cluster size using an in silico approach.
Topics: Acetaminophen; Cellulose; Chemistry, Pharmaceutical; Computer Simulation; Drug Compounding; Excipients; Particle Size; Powders; Pressure; Tablets; Tensile Strength | 2013 |
Toward better understanding of powder avalanching and shear cell parameters of drug-excipient blends to design minimal weight variability into pharmaceutical capsules.
Topics: Acetaminophen; Capsules; Cellulose; Drug Compounding; Excipients; Powders; Rheology | 2013 |
Real-time tablet formation monitoring with ultrasound measurements in eccentric single station tablet press.
Topics: Acetaminophen; Acoustics; Cellulose; Computer Systems; Drug Compounding; Stearic Acids; Tablets; Technology, Pharmaceutical; Tensile Strength | 2013 |
Continuous direct tablet compression: effects of impeller rotation rate, total feed rate and drug content on the tablet properties and drug release.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Automation; Cellulose; Chemical Phenomena; Colloids; Drug Compounding; Excipients; Finland; Hardness; Kinetics; Mechanical Phenomena; Models, Molecular; Quality Control; Silicon Dioxide; Solubility; Stearic Acids; Tablets; Technology, Pharmaceutical; Tensile Strength | 2013 |
Effect of experimental design on the prediction performance of calibration models based on near-infrared spectroscopy for pharmaceutical applications.
Topics: Acetaminophen; Calibration; Cellulose; Chemistry, Pharmaceutical; Lactose; Least-Squares Analysis; Models, Theoretical; Multivariate Analysis; Research Design; Spectroscopy, Near-Infrared | 2012 |
Drug release characteristics from chitosan-alginate matrix tablets based on the theory of self-assembled film.
Topics: Acetaminophen; Alginates; Cellulose; Chitosan; Glucuronic Acid; Hexuronic Acids; Hydrogen-Ion Concentration; Metformin; Osmolar Concentration; Stearic Acids; Tablets; Theophylline; Trimetazidine | 2013 |
Effects of powder flow properties on capsule filling weight uniformity.
Topics: Acetaminophen; Adhesiveness; Analgesics, Non-Narcotic; Capsules; Cellulose; Chemical Phenomena; Drug Compounding; Excipients; Lactose; Magnesium Silicates; Mechanical Phenomena; Particle Size; Powders; Quality Control; Rheology; Silicon Dioxide; Stearic Acids | 2013 |
Blending process modeling and control by multivariate curve resolution.
Topics: Acetaminophen; Algorithms; Calibration; Carboxymethylcellulose Sodium; Cellulose; Drug Compounding; Excipients; Humans; Lactose; Least-Squares Analysis; Multivariate Analysis; Reference Values; Spectrophotometry, Infrared; Stearic Acids | 2013 |
Distribution of a viscous binder during high shear granulation--sensitivity to the method of delivery and its impact on product properties.
Topics: Acetaminophen; Cellulose; Chlorpheniramine; Drug Compounding; Excipients; Hardness; Powders; Starch; Tablets; Technology, Pharmaceutical; Viscosity | 2014 |
Combined UV/vis and micro-tomography investigation of acetaminophen dissolution from granules.
Topics: Acetaminophen; Cellulose; Diffusion; Excipients; Kinetics; Porosity; Quantitative Structure-Activity Relationship; Solubility; Tomography, X-Ray Computed; Ultraviolet Rays | 2013 |
Compaction of functionalized calcium carbonate, a porous and crystalline microparticulate material with a lamellar surface.
Topics: Acetaminophen; Calcium Carbonate; Cellulose; Crystallization; Excipients; Mannitol; Porosity; Surface Properties; Tablets; Tensile Strength | 2014 |
Modeling strategies for pharmaceutical blend monitoring and end-point determination by near-infrared spectroscopy.
Topics: Acetaminophen; Carboxymethylcellulose Sodium; Cellulose; Chemistry, Pharmaceutical; Excipients; Lactose; Least-Squares Analysis; Models, Theoretical; Principal Component Analysis; Spectroscopy, Near-Infrared; Stearic Acids | 2014 |
An effect of cellulose crystallinity on the moisture absorbability of a pharmaceutical tablet studied by near-infrared spectroscopy.
Topics: Absorption, Physicochemical; Acetaminophen; Cellulose; Crystallization; Drug Compounding; Excipients; Friction; Microscopy, Electron, Scanning; Powders; Pressure; Spectroscopy, Near-Infrared; Surface Properties; Tablets; Temperature; Time Factors; Tomography, X-Ray Computed; Water; X-Ray Diffraction | 2014 |
Fine granules showing sustained drug release prepared by high-shear melt granulation using triglycerin full behenate and milled microcrystalline cellulose.
Topics: Acetaminophen; Bromhexine; Calorimetry, Differential Scanning; Cellulose; Delayed-Action Preparations; Drug Compounding; Drug Liberation; Fatty Acids; Particle Size; Powder Diffraction; X-Ray Diffraction | 2015 |
Density functional theory study on the formation of reactive benzoquinone imines by hydrogen abstraction.
Topics: Acetaminophen; Benzoquinones; Cytochrome P-450 Enzyme System; Hydrogen; Imines; Models, Chemical; Oxidation-Reduction; Porphyrins | 2015 |
Hydrogen-rich water protects against acetaminophen-induced hepatotoxicity in mice.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Endoplasmic Reticulum; Hydrogen; Liver; Liver Regeneration; Male; Mice, Inbred C57BL; Mitochondria, Liver; Necrosis; Oxidative Stress; Signal Transduction; Time Factors; Water | 2015 |
Statistical analysis and comparison of a continuous high shear granulator with a twin screw granulator: Effect of process parameters on critical granule attributes and granulation mechanisms.
Topics: Acetaminophen; Cellulose; Data Interpretation, Statistical; Lactose; Particle Size; Porosity; Rheology; Technology, Pharmaceutical | 2016 |
The use of partially hydrolysed polyvinyl alcohol for the production of high drug-loaded sustained release pellets via extrusion-spheronisation and coating: In vitro and in vivo evaluation.
Topics: Acetaminophen; Animals; Cellulose; Delayed-Action Preparations; Dogs; Drug Carriers; Drug Compounding; Drug Liberation; Male; Metformin; Particle Size; Polyvinyl Alcohol; Surface Properties; Technology, Pharmaceutical | 2017 |
Comparative binder efficiency modeling of dry granulation binders using roller compaction.
Topics: Acetaminophen; Cellulose; Chemistry, Pharmaceutical; Compressive Strength; Excipients; Hardness; Models, Theoretical; Particle Size; Povidone; Principal Component Analysis; Tablets; Technology, Pharmaceutical; Tensile Strength | 2017 |
The influence of excipients on physical and pharmaceutical properties of oral lyophilisates containing a pregabalin-acetaminophen combination.
Topics: Acetaminophen; Animals; Cellulose; Chemistry, Pharmaceutical; Drug Liberation; Excipients; Hypromellose Derivatives; Pregabalin; Rabbits; Rats; Rats, Wistar; Solubility; Tablets | 2017 |
Relationships between response surfaces for tablet characteristics of placebo and API-containing tablets manufactured by direct compression method.
Topics: Acetaminophen; Cellulose; Drug Compounding; Drug Design; Excipients; Lactose; Niacin; Placebos; Pressure; Pyridoxine; Salicylamides; Starch; Stearic Acids; Tablets | 2017 |
Application of X-Ray Sensors for In-line and Noninvasive Monitoring of Mass Flow Rate in Continuous Tablet Manufacturing.
Topics: Acetaminophen; Calibration; Cellulose; Drug Compounding; Powders; Rheology; Tablets; X-Rays | 2017 |
Provoking an end-to-end continuous direct compression line with raw materials prone to segregation.
Topics: Acetaminophen; Cellulose; Drug Compounding; Fumarates; Mannitol; Particle Size; Powders; Pressure; Stearates; Tablets; Tensile Strength | 2017 |
Modeling the effects of material properties on tablet compaction: A building block for controlling both batch and continuous pharmaceutical manufacturing processes.
Topics: Acetaminophen; Cellulose; Chemistry, Pharmaceutical; Excipients; Lactose; Models, Theoretical; Stearic Acids; Tablets; Tensile Strength | 2018 |
Granule formation and structure from single drop impact on heterogeneous powder beds.
Topics: Acetaminophen; Cellulose; Drug Compounding; Excipients; Particle Size; Powders; Surface Properties; Water | 2018 |
Influence of moisture variation on the performance of Raman spectroscopy in quantitative pharmaceutical analyses.
Topics: Acetaminophen; Administration, Oral; Calibration; Cellulose; Chemistry, Pharmaceutical; Drug Compounding; Excipients; Humidity; Lactose; Models, Chemical; Spectrum Analysis, Raman; Stearic Acids | 2019 |
Comparison between integrated continuous direct compression line and batch processing - The effect of raw material properties.
Topics: Acetaminophen; Cellulose; Excipients; Mannitol; Particle Size; Powders; Technology, Pharmaceutical | 2019 |
Fast Raman chemical imaging of tablets with non-flat surfaces.
Topics: Acetaminophen; Aspirin; Caffeine; Cellulose; Least-Squares Analysis; Spectrum Analysis, Raman; Tablets; Technology, Pharmaceutical | 2019 |
Synchrotron-based X-ray in-situ imaging techniques for advancing the understanding of pharmaceutical granulation.
Topics: Acetaminophen; Carboxymethylcellulose Sodium; Cellulose; Drug Compounding; Excipients; Humans; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Lactose; Molecular Imaging; Particle Size; Powders; Synchrotrons; Technology, Pharmaceutical; X-Rays | 2019 |
Numerical study for tableting process in consideration of compression speed.
Topics: Acetaminophen; Cellulose; Computer Simulation; Excipients; Lactose; Models, Theoretical; Pressure; Stearic Acids; Tablets; Technology, Pharmaceutical | 2020 |
A novel approach to avoid capping and/or lamination by application of external lower punch vibration.
Topics: Acetaminophen; Cellulose; Drug Compounding; Excipients; Stearic Acids; Tablets; Tensile Strength; Vibration | 2020 |
Simultaneous investigation of the liquid transport and swelling performance during tablet disintegration.
Topics: Acetaminophen; Calcium Carbonate; Cellulose; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Excipients; Humans; Kinetics; Porosity; Tablets; Terahertz Spectroscopy; Theophylline | 2020 |
Controlled release evaluation of paracetamol loaded amine functionalized mesoporous silica KCC1 compared to microcrystalline cellulose based tablets.
Topics: Acetaminophen; Adsorption; Amines; Cellulose; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Drug Liberation; Humans; Porosity; Silicon Dioxide; Surface Properties; Tablets | 2021 |
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Topics: Acetaminophen; Acetylcysteine; Benzoquinones; COVID-19 Drug Treatment; Humans; Hydrogen; Imines; Vitamin K; Vitamin K Epoxide Reductases | 2022 |