acetaminophen and guaifenesin

acetaminophen has been researched along with guaifenesin in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199013 (39.39)18.7374
1990's3 (9.09)18.2507
2000's5 (15.15)29.6817
2010's11 (33.33)24.3611
2020's1 (3.03)2.80

Authors

AuthorsStudies
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cantwell, FF; Mohammed, HY1
Cox, GB; Loscombe, CR; Sugden, K1
Tománková, H; Vasatová, M1
Janku, I; Kordac, V; Perlík, F1
Bauer, M; Bauerová, J; Bojar, Z; Dobrotka, G; Marsinová, G1
Johansson, G; Laakso, ML; Lindroos, F1
Doyle, TD; Levine, J1
Carnevale, L1
McSharry, WO; Savage, IV1
Adriani, Y; Indrayanto, G; Sunarto, A1
Dolezal, T; Krsiak, M1
Su, WT; Tang, X; Wu, XH; Zhang, LQ; Zhu, XL1
FICHSEL, H1
Chen, X; Huang, J; Kong, Z; Zhong, D1
Jiang, JG; Song, GS; Zhang, XR; Zhang, YH1
Janin, A; Monnet, J1
Bristow, T; Lewis, C; Ray, A; Wren, S1
Mohamed, HM; Yehia, AM2
Essam, HM; Yehia, AM1
Abdelaleem, EA; Abdelrahman, MM; Abdelwahab, NS1
Abdel Moneim, MM; Belal, SF; El-Kimary, EI; Khamis, EF1
Bolton, B; Chohan, H; Dassow, B; Fakayode, SO; Galvez, K1
Breäs, R; Crommelin, DJ; Poelma, FG; Tukker, JJ1
Hoon, JR1
Ivey, KJ1
Marcinkiewicz, M; Peura, DA; Sarosiek, J1
Conway, BR; Grattan, TJ; Irwin, WJ; Shaw, LR1

Reviews

2 review(s) available for acetaminophen and guaifenesin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Gastrointestinal effects of antipyretic analgesics.
    The American journal of medicine, 1983, Nov-14, Volume: 75, Issue:5A

    Topics: Acetaminophen; Adenosine Triphosphate; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bicarbonates; Child; Duodenal Ulcer; Esophagitis; Gastric Mucosa; Gastrointestinal Diseases; Gastrointestinal Hemorrhage; Gastroscopy; Humans; Mucus; Occult Blood; Prostaglandin Antagonists; Stomach Ulcer; Time Factors

1983

Trials

3 trial(s) available for acetaminophen and guaifenesin

ArticleYear
[Symptomatic treatment of acute inflammation of the upper respiratory airways in pediatrics].
    Minerva pediatrica, 1977, Feb-18, Volume: 29, Issue:5

    Topics: Acetaminophen; Acute Disease; Analgesics; Animals; Child, Preschool; Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Female; Feprazone; Guaifenesin; Humans; Infant; Male; Phenylbutazone; Rabbits; Respiratory Tract Infections; Suppositories

1977
Bioavailability of paracetamol, phenylephrine hydrochloride and guaifenesin in a fixed-combination syrup versus an oral reference product.
    The Journal of international medical research, 2014, Volume: 42, Issue:2

    Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Biological Availability; Cross-Over Studies; Drug Combinations; Expectorants; Female; Guaifenesin; Humans; Male; Middle Aged; Nasal Decongestants; Phenylephrine; Young Adult

2014
The relationship between the content of aggressive and protective components in gastric juice and endoscopic findings after naproxen sodium and acetaminophen administration.
    The American journal of gastroenterology, 1996, Volume: 91, Issue:2

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Centrifugation, Density Gradient; Cross-Over Studies; Double-Blind Method; Endoscopy; Female; Gastric Juice; Gastric Mucins; Gastric Mucosa; Humans; Male; Middle Aged; Mucus; Naproxen; Pepsin A; Placebos; Proteins; Viscosity

1996

Other Studies

28 other study(ies) available for acetaminophen and guaifenesin

ArticleYear
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Liquid chromatographic analysis of pharmaceutical syrups using pre-columns and salt-adsorption on amberlite XAD-2.
    Analytical chemistry, 1978, Volume: 50, Issue:3

    Topics: Acetaminophen; Chromatography, Liquid; Dextromethorphan; Expectorants; Guaifenesin; Phenylephrine; Polystyrenes; Resins, Synthetic

1978
Some applications of bonded-phase high-performance liquid chromatography to the analysis of pharmaceutical formulations.
    Analytica chimica acta, 1977, Volume: 92, Issue:2

    Topics: Acetaminophen; Aspirin; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Contamination; Guaifenesin; Hydroxybenzoates; Methods; Phenacetin; Phenylephrine; Phenylpropanolamine; Prednisolone; Prednisone; Tyrothricin

1977
[Densitometric determination of propyphenazone, paracetamol, guaiacol glycerol ether, caffeine and acetylsalicylic acid in analgesic-antipyretic preparations with thin-layer chromatography].
    Die Pharmazie, 1989, Volume: 44, Issue:3

    Topics: Acetaminophen; Antipyrine; Aspirin; Caffeine; Chromatography, Thin Layer; Densitometry; Drug Combinations; Guaifenesin

1989
The effect of guaiphenesin on absorption and bioavailability of paracetamol from composite analgesic preparations.
    International journal of clinical pharmacology, therapy, and toxicology, 1988, Volume: 26, Issue:8

    Topics: Acetaminophen; Administration, Oral; Adult; Biological Availability; Drug Combinations; Female; Guaifenesin; Humans; Intestinal Absorption; Male; Middle Aged

1988
[Significance of the interaction between analgesic-antipyretics and ethanol in forensic medicine investigations].
    Bratislavske lekarske listy, 1987, Volume: 87, Issue:4

    Topics: Accidents, Traffic; Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Codeine; Drug Combinations; Drug Interactions; Ethanol; Forensic Medicine; Guaifenesin; Humans; Male; Middle Aged; Phenobarbital; Psychomotor Performance

1987
Deoxyglucose-autoradiography of the hypothalamus after food deprivation in the mouse.
    Activitas nervosa superior, 1986, Volume: 28, Issue:2

    Topics: Acetaminophen; Animals; Autoradiography; Caffeine; Deoxy Sugars; Deoxyglucose; Drug Combinations; Food Deprivation; Guaifenesin; Hypothalamus; Male; Mice; Mice, Inbred Strains

1986
Determination of phenylephrine in combinations with other drugs.
    Journal of pharmaceutical sciences, 1967, Volume: 56, Issue:5

    Topics: Acetaminophen; Antitussive Agents; Aspirin; Chlorpheniramine; Chromatography; Dosage Forms; Expectorants; Guaifenesin; Histamine H1 Antagonists; Magnesium; Phenolphthaleins; Phenylephrine; Phenylpropanolamine; Solutions; Sympathomimetics; Tablets; Ultraviolet Rays

1967
Simultaneous determination of acetaminophen, guaifenesin, pseudoephedrine, pholcodine, and paraben preservatives in cough mixture by high-performance liquid chromatography.
    Journal of pharmaceutical sciences, 1983, Volume: 72, Issue:2

    Topics: Acetaminophen; Antitussive Agents; Chromatography, High Pressure Liquid; Codeine; Drug Combinations; Ephedrine; Guaifenesin; Morpholines; Parabens

1983
Simultaneous high-pressure liquid chromatographic determination of acetaminophen, guaifenesin, and dextromethorphan hydrobromide in cough syrup.
    Journal of pharmaceutical sciences, 1980, Volume: 69, Issue:2

    Topics: Acetaminophen; Antitussive Agents; Chromatography, High Pressure Liquid; Dextromethorphan; Drug Combinations; Guaifenesin; Levorphanol; Methods

1980
Simultaneous assay of phenylpropanolamine hydrochloride, caffeine, paracetamol, glycerylguaiacolate and chlorpheniramine maleate in Silabat tablet using HPLC with diode array detection.
    Journal of pharmaceutical and biomedical analysis, 1995, Volume: 13, Issue:12

    Topics: Acetaminophen; Caffeine; Chlorpheniramine; Chromatography, High Pressure Liquid; Drug Combinations; Guaifenesin; Indicators and Reagents; Phenylpropanolamine; Tablets

1995
Guaifenesin enhances the analgesic potency of paracetamol in mice.
    Naunyn-Schmiedeberg's archives of pharmacology, 2002, Volume: 366, Issue:6

    Topics: Acetaminophen; Analgesics; Animals; Drug Synergism; Guaifenesin; Male; Mice; Motor Activity; Pain Measurement

2002
[Research into simultaneous spectrophotometric determination of components in cough syrup by principal component regression method].
    Guang pu xue yu guang pu fen xi = Guang pu, 2002, Volume: 22, Issue:3

    Topics: Acetaminophen; Aminophenols; Analgesics, Non-Narcotic; Caffeine; Chlorpheniramine; Drug Combinations; Expectorants; Guaifenesin; Histamine H1 Antagonists; Sensitivity and Specificity; Spectrophotometry, Ultraviolet

2002
[EXPERIENCES WITH A NEW ANTIPYRETIC AND ANALGESIC IN A NEW RECTAL CAPSULE FORM].
    Kinderarztliche Praxis, 1963, Volume: 31

    Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Bronchitis; Bronchopneumonia; Capsules; Child; Guaifenesin; Humans; Infant; Influenza, Human; Otitis; Pharyngitis; Rhinitis; Salicylamides; Tonsillitis; Valerian

1963
Sensitive liquid chromatography-tandem mass spectrometry method for the simultaneous determination of paracetamol and guaifenesin in human plasma.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Mar-25, Volume: 817, Issue:2

    Topics: Acetaminophen; Administration, Oral; Guaifenesin; Humans; Reproducibility of Results; Sensitivity and Specificity

2005
Best drugs for what ails you: the brands to buy--and those to skip.
    Consumer reports, 2009, Volume: 74, Issue:9

    Topics: Acetaminophen; Anesthetics, Local; Cetirizine; Chlorpheniramine; Common Cold; Cough; Dextromethorphan; Diphenhydramine; Drug Costs; Drug Therapy; Emergencies; Expectorants; First Aid; Glycerol; Guaifenesin; Histamine Antagonists; Honey; Humans; Hypersensitivity; Ibuprofen; Influenza Vaccines; Influenza, Human; Loratadine; Nonprescription Drugs; Oxymetazoline; Pharyngitis; Propiophenones; Pseudoephedrine; Rhinitis; Sodium Chloride

2009
[Rapid identification 15 effective components of anti common cold medicine with MRM by LC-MS/MS].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2013, Volume: 48, Issue:1

    Topics: Acetaminophen; Acetanilides; Amantadine; Aminopyrine; Anti-Inflammatory Agents, Non-Steroidal; Antipyretics; Antipyrine; Caffeine; Chlorpheniramine; Chromatography, Liquid; Diclofenac; Diphenhydramine; Drug Contamination; Drug Stability; Ephedrine; Guaifenesin; Promethazine; Pseudoephedrine; Reproducibility of Results; Salicylates; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2013
Determining the suitability of mass spectrometry for understanding the dissolution processes involved with pharmaceutical tablets.
    Rapid communications in mass spectrometry : RCM, 2015, Jun-30, Volume: 29, Issue:12

    Topics: Acetaminophen; Buffers; Chemistry, Pharmaceutical; Guaifenesin; Lactose; Mass Spectrometry; Online Systems; Phenylephrine; Salts; Solubility; Tablets

2015
Chemometrics resolution and quantification power evaluation: Application on pharmaceutical quaternary mixture of Paracetamol, Guaifenesin, Phenylephrine and p-aminophenol.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2016, Jan-05, Volume: 152

    Topics: Acetaminophen; Aminophenols; Analgesics, Non-Narcotic; Drug Combinations; Drug Contamination; Expectorants; Guaifenesin; Least-Squares Analysis; Multivariate Analysis; Nasal Decongestants; Neural Networks, Computer; Phenylephrine; Principal Component Analysis; Spectrophotometry

2016
Green approach using monolithic column for simultaneous determination of coformulated drugs.
    Journal of separation science, 2016, Volume: 39, Issue:11

    Topics: Acetaminophen; Green Chemistry Technology; Guaifenesin; Molecular Structure; Phenylephrine; Solvents

2016
Development and validation of a generic high-performance liquid chromatography for the simultaneous separation and determination of six cough ingredients: Robustness study on core-shell particles.
    Journal of separation science, 2016, Volume: 39, Issue:17

    Topics: Acetaminophen; Antitussive Agents; Chromatography, High Pressure Liquid; Dextromethorphan; Doxylamine; Ephedrine; Guaifenesin; Humans; Phenylephrine

2016
HPTLC-Densitometric Method for Determination of Ascorbic Acid, Paracetamol and Guaifenesin in Presence of Their Toxic Impurities.
    Journal of chromatographic science, 2019, Feb-01, Volume: 57, Issue:2

    Topics: Acetaminophen; Ascorbic Acid; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Densitometry; Drug Contamination; Guaifenesin; Limit of Detection; Linear Models; Reproducibility of Results

2019
Robust Chromatographic Methods for the Analysis of Two Quaternary Mixtures Containing Paracetamol, Codeine, Guaifenesin and Pseudoephedrine or Phenylephrine in their Dosage Forms.
    Journal of chromatographic science, 2019, Oct-17, Volume: 57, Issue:9

    Topics: Acetaminophen; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Codeine; Guaifenesin; Limit of Detection; Linear Models; Multi-Ingredient Cold, Flu, and Allergy Medications; Phenylephrine; Pseudoephedrine; Reproducibility of Results; Tablets

2019
Rapid screening and multicomponent quantifications of active components of oral syrup over-the-counter medications by Raman and UV-visible spectroscopy and multivariate regression analysis.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2024, Jan-15, Volume: 305

    Topics: Acetaminophen; Aged; Child; Guaifenesin; Humans; Least-Squares Analysis; Multivariate Analysis; Pharmaceutical Preparations; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman

2024
Intestinal absorption of drugs. The influence of mixed micelles on on the disappearance kinetics of drugs from the small intestine of the rat.
    The Journal of pharmacy and pharmacology, 1991, Volume: 43, Issue:5

    Topics: Acetaminophen; Animals; Chromatography, High Pressure Liquid; Dantrolene; Griseofulvin; Intestinal Absorption; Intestine, Small; Ketoconazole; Kinetics; Lysophosphatidylcholines; Micelles; Models, Biological; Mucus; Rats; Solubility; Swine; Taurocholic Acid; Theophylline

1991
Aspirin gastritis examined with intragastric photography.
    IMS, Industrial medicine and surgery, 1969, Volume: 38, Issue:8

    Topics: Acetaminophen; Adult; Antacids; Aspirin; Buffers; Drug Hypersensitivity; Drug Synergism; Female; Gastric Mucosa; Gastritis; Gastrointestinal Hemorrhage; Gastrointestinal Motility; Gastroscopy; Humans; Male; Middle Aged; Mucus; Photography

1969
The influence of excipients on the diffusion of ibuprofen and paracetamol in gastric mucus.
    International journal of pharmaceutics, 2005, Feb-16, Volume: 290, Issue:1-2

    Topics: Acetaminophen; Animals; Excipients; Gastric Mucosa; Ibuprofen; In Vitro Techniques; Mucus; Solubility; Stomach; Swine

2005