acetaminophen and glycine

acetaminophen has been researched along with glycine in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19906 (26.09)18.7374
1990's5 (21.74)18.2507
2000's3 (13.04)29.6817
2010's6 (26.09)24.3611
2020's3 (13.04)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Campillo, NE; Guerra, A; Páez, JA1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Jones, DP; Jörnvall, H; Moldfus, P; Ormstad, K; Orrenius, S; Stead, AH1
Jackson, AA; Persaud, C1
George, CF; Macklin, B; Renwick, AG; Usman, F; Waller, DG1
Itoh, T; Kamisaki, Y; Kitamura, Y1
Levy, G1
Hayton, WL; Levy, G; Regårdh, CG1
Thomas, P; Wofford, HW1
Higuchi, T; Kovach, IM; Pitman, IH1
Antoci, G; Bianchi, P; Catarci, M; Gossetti, F; La Pinta, M; Nanni, G; Negro, P; Nolfe, G; Sarro, G1
Affinito, P; Colace, G; La Pinta, M; Nappi, C; Nolfe, G; Ruotolo, C1
De Santis, E; La Pinta, M; Nolfe, G1
Jaeschke, H; Kim, JS; Kon, K; Lemasters, JJ1
Samcová, E; Soukupová, M; Stulík, K; Tůma, P1
Bergh, JJ; Kotze, HF; Mienie, LJ; Terre'Blanche, G; Viljoen, J1
Fukami, T; Kawahata, M; Maeno, Y; Ozeki, T; Suzuki, T; Tagami, T; Tomono, K; Yamaguchi, K1
Good, P1
Colle, I; Debacker, PJ; Devisscher, L; Geerts, A; Lefere, S; Raevens, S; Van Campenhout, S; Van Vlierberghe, H; Verhelst, X1
Barsch, L; Eulenburg, V; Leffler, A; Werdehausen, R1
Fukami, T; Fukui, K; Otaka, K; Suzuki, N; Suzuki, T1

Reviews

1 review(s) available for acetaminophen and glycine

ArticleYear
Drug biotransformation interactions in man: nonnarcotic analgesics.
    Annals of the New York Academy of Sciences, 1971, Jul-06, Volume: 179

    Topics: Acetaminophen; Adult; Analgesics; Benzoates; Biotransformation; Cysteine; Drug Synergism; Ethanol; Glucuronates; Glycine; Humans; Kinetics; Male; Metabolism; Salicylamides; Salicylates; Sodium Salicylate; Sulfuric Acids

1971

Trials

4 trial(s) available for acetaminophen and glycine

ArticleYear
Oral amino acids and gastric emptying: an investigation of the mechanism of levodopa-induced gastric stasis.
    British journal of clinical pharmacology, 1991, Volume: 32, Issue:6

    Topics: Acetaminophen; Administration, Oral; Adult; Chromatography, High Pressure Liquid; Female; Gastric Emptying; Glycine; Humans; Levodopa; Male; Tryptophan

1991
[The drug treatment of postoperative pain].
    La Clinica terapeutica, 1993, Volume: 142, Issue:1 Pt 2

    Topics: Acetaminophen; Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug Tolerance; Female; Glycine; Humans; Italy; Male; Middle Aged; Minor Surgical Procedures; Pain Measurement; Pain, Postoperative; Pyrroles

1993
[The treatment of postoperative pain in obstetrical-gynecologic surgery. A comparative study between ST-679 and paracetamol].
    La Clinica terapeutica, 1993, Volume: 142, Issue:1 Pt 2

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug Tolerance; Female; Genital Diseases, Female; Glycine; Humans; Middle Aged; Pain Measurement; Pain, Postoperative; Pregnancy; Pregnancy Complications; Pyrroles

1993
[An evaluation of the analgesic activity and tolerance of ST-679 in patients with pain following orthopedic and traumatological interventions].
    La Clinica terapeutica, 1993, Volume: 142, Issue:1 Pt 2

    Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug Tolerance; Female; Glycine; Humans; Male; Middle Aged; Orthopedics; Pain Measurement; Pain, Postoperative; Pyrroles; Wounds and Injuries

1993

Other Studies

18 other study(ies) available for acetaminophen and glycine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Metabolism of glutathione and a glutathione conjugate by isolated kidney cells.
    The Journal of biological chemistry, 1979, Apr-25, Volume: 254, Issue:8

    Topics: Acetaminophen; Animals; Antimycin A; Cell Membrane; Cyanides; Cystine; Glutathione; Glycine; In Vitro Techniques; Kidney; Kinetics; Male; Rats; Serine

1979
5-L-oxoprolinuria and glycine sufficiency.
    Clinical chemistry, 1991, Volume: 37, Issue:9

    Topics: Acetaminophen; Adult; Dipeptides; Female; Glutamate-Cysteine Ligase; Glutathione; Glutathione Synthase; Glycine; Humans; Infant; Pregnancy; Pyrrolidonecarboxylic Acid; Reference Values

1991
Hepatoprotective effects of cystathionine against acetaminophen-induced necrosis.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:2

    Topics: Acetaminophen; Alkynes; Animals; Cystathionine; Glutathione; Glycine; Liver; Male; Necrosis; Pargyline; Rats; Rats, Inbred Strains; Taurine

1989
Effect of complex formation on drug absorption. XIV. Effect of N,N-di-n-propylpropionamide on intestinal absorption of certain nonsteroid drugs in the rat.
    Journal of pharmaceutical sciences, 1972, Volume: 61, Issue:3

    Topics: Acetaminophen; Amides; Aminohippuric Acids; Animals; Barbiturates; Coloring Agents; Drug Interactions; Glycine; Hydrogen-Ion Concentration; Intestinal Absorption; Male; Propionates; Propylamines; Rats; Rats, Inbred Strains; Riboflavin; Salicylates; Structure-Activity Relationship; Tetracycline

1972
Effects of metals and organic compounds on hepatic glutathione, cysteine, and acid-soluble thiol levels in mullet (Mugil cephalus L.).
    Toxicology and applied pharmacology, 1984, Volume: 76, Issue:1

    Topics: Acetaminophen; Animals; Benzofurans; Cadmium; Cysteine; Fishes; Fluorenes; Food Deprivation; Fuel Oils; Glutathione; Glycine; Liver; Mercury; Pentachlorophenol; Sulfhydryl Compounds

1984
Amino acid esters of phenols as prodrugs: synthesis and stability of glycine, beta-aspartic acid, and alpha-aspartic acid esters of p-acetamidophenol.
    Journal of pharmaceutical sciences, 1981, Volume: 70, Issue:8

    Topics: Acetaminophen; Aspartic Acid; Drug Stability; Esters; Glycine; Hydrolysis

1981
Mitochondrial permeability transition in acetaminophen-induced necrosis and apoptosis of cultured mouse hepatocytes.
    Hepatology (Baltimore, Md.), 2004, Volume: 40, Issue:5

    Topics: Acetaminophen; Adenosine Triphosphate; Analgesics, Non-Narcotic; Animals; Apoptosis; Caspase 3; Caspases; Cell Death; Cells, Cultured; Cyclosporine; Drug Synergism; Fructose; Glycine; Hepatocytes; Immunosuppressive Agents; Ion Channels; Male; Mice; Mice, Inbred Strains; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Necrosis; Time Factors

2004
A determination of submicromolar concentrations of glycine in periaqueductal gray matter microdialyzates using capillary zone electrophoresis with contactless conductivity detection.
    Electrophoresis, 2009, Volume: 30, Issue:19

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Carrageenan; Electric Conductivity; Electrophoresis, Capillary; Glycine; Male; Pain; Periaqueductal Gray; Rats; Rats, Wistar; Reproducibility of Results; Sensitivity and Specificity

2009
Paracetamol prevents hyperglycinemia in vervet monkeys treated with valproate.
    Metabolic brain disease, 2012, Volume: 27, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anticonvulsants; Chlorocebus aethiops; Disease Models, Animal; Female; Glycine; Hyperglycinemia, Nonketotic; Male; Pilot Projects; Valproic Acid

2012
Novel pharmaceutical cocrystal consisting of paracetamol and trimethylglycine, a new promising cocrystal former.
    International journal of pharmaceutics, 2014, Oct-01, Volume: 473, Issue:1-2

    Topics: Acetaminophen; Antipyretics; Crystallization; Glycine; Solubility; Tablets; Taste

2014
Evidence the U.S. autism epidemic initiated by acetaminophen (Tylenol) is aggravated by oral antibiotic amoxicillin/clavulanate (Augmentin) and now exponentially by herbicide glyphosate (Roundup).
    Clinical nutrition ESPEN, 2018, Volume: 23

    Topics: Acetaminophen; Amoxicillin-Potassium Clavulanate Combination; Androgens; Aromatase; Aromatase Inhibitors; Autistic Disorder; Estrogens; Female; Glycine; Glyphosate; Herbicides; Humans; Male; Placenta; Pregnancy; Prenatal Exposure Delayed Effects; United States

2018
Combination of sivelestat and N-acetylcysteine alleviates the inflammatory response and exceeds standard treatment for acetaminophen-induced liver injury.
    Journal of leukocyte biology, 2020, Volume: 107, Issue:2

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Free Radical Scavengers; Glycine; Inflammation; Male; Mice; Mice, Inbred C57BL; Serine Proteinase Inhibitors; Sulfonamides

2020
Modulation of Glycinergic Neurotransmission may Contribute to the Analgesic Effects of Propacetamol.
    Biomolecules, 2021, 03-25, Volume: 11, Issue:4

    Topics: Acetaminophen; Allosteric Regulation; Analgesics; Animals; Glycine; Glycine Plasma Membrane Transport Proteins; Oocytes; Patch-Clamp Techniques; Receptors, Glycine; Synaptic Transmission; Xenopus laevis

2021
Monitoring of Cocrystal Dissociation during the Wet Granulation Process in the Presence of Disintegrants by Using Low-Frequency Raman Spectroscopy.
    Chemical & pharmaceutical bulletin, 2021, Volume: 69, Issue:9

    Topics: Acetaminophen; Crystallography, X-Ray; Glycine; Maleates; Models, Molecular; Oxalic Acid; Spectrum Analysis, Raman

2021