acetaminophen has been researched along with glutathione disulfide in 50 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (24.00) | 18.7374 |
| 1990's | 9 (18.00) | 18.2507 |
| 2000's | 9 (18.00) | 29.6817 |
| 2010's | 20 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Strubelt, O; Younes, M | 1 |
| Davies, MH; Schamber, GJ; Schnell, RC | 1 |
| Fischer, V; Mason, RP; Ramakrishna Rao, DN | 1 |
| Farber, JL; Kyle, ME; Sakaida, I; Serroni, A | 1 |
| Fujihara, Y; Iguchi, S; Kaneo, Y; Kozawa, Y; Mori, H; Tanaka, T | 1 |
| Nelson, SD; Tirmenstein, MA | 1 |
| Jaeschke, H; Smith, CV | 1 |
| Moldéus, P; Norbeck, K; Ross, D | 1 |
| Bosman, P; de Vries, J; van de Straat, R; Vermeulen, NP; Vromans, RM | 1 |
| Coles, B; Hinson, JA; Ketterer, B; Nelson, SD; Wardman, P; Wilson, I | 1 |
| Albano, E; Larsson, R; Moldéus, P; Nelson, SD; Porubek, D; Ross, D; Rundgren, M | 1 |
| McGirr, LG; O'Brien, PJ; Subrahmanyam, VV | 1 |
| Berlin, T; Larsson, R; Moldéus, P; Olsson, LI; Ross, D | 1 |
| Adams, JD; Lauterburg, BH; Mitchell, JR | 1 |
| Hughes, H; Lauterburg, BH; Mitchell, JR; Smith, CV | 1 |
| Corcoran, GB; Hughes, H; Lauterburg, BH; Mitchell, JR; Smith, CV | 1 |
| Boveris, A; Cutrín, JC; Llesuy, S; Lores Arnaiz, S | 1 |
| Genestie-Denis, I; Guizon, I; Lorenzon, G; Vandeputte, C; Vannier, B | 1 |
| Li, JY; Wang, L; Zhang, XJ | 1 |
| Adamson, GM; Harman, AW | 1 |
| Chen, L; Inouye, M; Mirochnitchenko, O; Reuhl, K; Weisbrot-Lefkowitz, M; Yang, C | 1 |
| Allison, RW; Burkhard, MJ; Lappin, MR; Lassen, ED | 1 |
| Chen, TS; Ray, MB; Srinivasan, C; Williams, WM | 1 |
| Chen, TS; Song, H | 1 |
| Matsura, T; Sumioka, I; Yamada, K | 1 |
| Fettman, MJ; Mason, G; Twedt, DC; Webb, CB | 1 |
| Bajt, ML; Farhood, A; Jaeschke, H; Knight, TR | 1 |
| Hinson, JA; Jaeschke, H; James, LP; Knight, TR; McCullough, SS | 1 |
| Horie, T; Masubuchi, Y; Suda, C | 1 |
| Červinková, Z; Kanďár, R; Křiváková, P; Kucera, O; Lotková, H; Mužáková, V; Rousar, T | 1 |
| Acharya, M; Lau-Cam, CA | 2 |
| Jaeschke, H; Lebofsky, M; Ramachandran, A; Weinman, SA | 1 |
| Brandolini-Bunlon, M; Dardevet, D; Dubray, C; Ducheix, G; Glomot, F; Lyan, B; Papet, I; Pickering, G; Pujos-Guillot, E | 1 |
| Bajt, ML; Farhood, A; Jaeschke, H; Lebofsky, M; Lemasters, JJ; Ramachandran, A; Yan, HM | 1 |
| Cervinková, Z; Haňáčková, L; Kučera, O; Lotková, H; Podhola, M; Roušar, T; Staňková, P | 1 |
| Ali, A; Ando, Y; Beger, R; Davis, K; Greenhaw, J; Hinson, JA; Muskhelishvili, L; Pence, LM; Roberts, DW; Salminen, WF; Shi, Q; Sun, J; Yang, X | 1 |
| Bridi, JC; Carbajo-Pescador, S; Carvalho, NR; da Rocha, JB; da Rosa, EJ; da Silva, MH; González-Gallego, J; Mauriz, JL; Soares, FA | 1 |
| He, YY; Jia, FL; Liu, WX; Zhang, BX | 1 |
| Hashimoto, T; Kobayashi, A; Kondo, K; Kuno, H; Shoda, T; Sugai, S; Suzuki, Y; Takahashi, A; Toyoda, K; Yamada, N | 1 |
| Cao, L; Langley, M; Roberts, J; Teffera, Y; Waldon, D; Wells, M; Zhao, Z | 1 |
| Cesla, P; Jankovičová, B; Nýdlová, E; Roušar, T; Ventura, K; Vrbová, M | 1 |
| Arakawa, S; Igarashi, I; Kai, K; Maejima, T; Sanbuissho, A; Teranishi, M | 1 |
| Aycan, IÖ; Evliyaoğlu, O; Fırat, U; Kavak, GÖ; Tokgöz, O; Tüfek, A; Turgut, H; Yüksel, MU | 1 |
| Chen, BH; Huang, JH; Lin, WT; Lu, YF; Tien, YH; Wang Hsu, GS | 1 |
| Breckenridge, DG; Farhood, A; Jaeschke, H; Lebofsky, M; Liles, JT; Ramachandran, A; Xie, Y | 1 |
| Cogliati, B; Crespo Yanguas, S; da Silva, TC; Farhood, A; Jaeschke, H; Lebofsky, M; Maes, M; Maria Monteiro de Araújo, C; McGill, MR; Tiburcio, T; Veloso Alves Pereira, I; Vinken, M; Willebrords, J; Zaidan Dagli, ML | 1 |
| Durham, D; Jaeschke, H; Kennon-McGill, S; McGill, MR | 1 |
| Chen, JN; Huang, QH; Lai, XP; Liang, JL; Lin, GS; Liu, YH; Su, ZR; Wu, JZ; Wu, X; Xu, LQ | 1 |
3 trial(s) available for acetaminophen and glutathione disulfide
| Article | Year |
|---|---|
Effect of a bioflavonoid dietary supplement on acetaminophen-induced oxidative injury to feline erythrocytes.
Topics: Acetaminophen; Animals; Antioxidants; Cats; Dietary Supplements; Erythrocytes; Female; Flavonoids; Glutathione; Glutathione Disulfide; Heinz Bodies; Hematocrit; Male; Methemoglobin; Oxidation-Reduction | 2000 |
S-adenosylmethionine (SAMe) in a feline acetaminophen model of oxidative injury.
Topics: Acetaminophen; Animals; Antioxidants; Cat Diseases; Cats; Chemical and Drug Induced Liver Injury; Erythrocytes; Glutathione; Glutathione Disulfide; Liver; S-Adenosylmethionine; Thiobarbituric Acid Reactive Substances; Time Factors | 2003 |
Therapeutic paracetamol treatment in older persons induces dietary and metabolic modifications related to sulfur amino acids.
Topics: Acetaminophen; Aged; Aging; Algorithms; Amino Acids, Sulfur; Analgesics, Non-Narcotic; Arthritis; Biomarkers; Dietary Proteins; Female; Glutathione Disulfide; Humans; Male; Predictive Value of Tests; Sensitivity and Specificity; Sulfates | 2012 |
47 other study(ies) available for acetaminophen and glutathione disulfide
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
The toxicological relevance of paracetamol-induced inhibition of hepatic respiration and ATP depletion.
Topics: Acetaminophen; Adenosine Triphosphate; Animals; Bile; Glutathione; Glutathione Disulfide; Glycolysis; L-Lactate Dehydrogenase; Liver; Male; Oxygen Consumption; Perfusion; Rats; Rats, Inbred Strains; Transaminases | 1992 |
Oltipraz-induced amelioration of acetaminophen hepatotoxicity in hamsters. I. Lack of dependence on glutathione.
Topics: Acetaminophen; Animals; Cricetinae; Glutathione; Glutathione Disulfide; Liver; Male; Mesocricetus; Oxidation-Reduction; Pyrazines; Schistosomicides; Thiones; Thiophenes | 1991 |
Glutathione and ascorbate reduction of the acetaminophen radical formed by peroxidase. Detection of the glutathione disulfide radical anion and the ascorbyl radical.
Topics: Acetaminophen; Ascorbic Acid; Electron Spin Resonance Spectroscopy; Free Radicals; Glutathione; Glutathione Disulfide; Oxidation-Reduction; Oxygen Consumption; Peroxidases | 1990 |
Metabolism of acetaminophen by cultured rat hepatocytes. Depletion of protein thiol groups without any loss of viability.
Topics: Acetaminophen; Animals; Carmustine; Cells, Cultured; Deferoxamine; Glutathione; Glutathione Disulfide; Liver; Male; Phenylenediamines; Proteins; Rats; Rats, Inbred Strains; Sulfhydryl Compounds | 1990 |
Intrahepatic delivery of glutathione by conjugation to dextran.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Chromatography, Gel; Chromatography, High Pressure Liquid; Dextrans; Fluorometry; Glutathione; Glutathione Disulfide; Liver; Liver Diseases; Male; Mice; Mice, Inbred Strains; Prodrugs | 1989 |
Subcellular binding and effects on calcium homeostasis produced by acetaminophen and a nonhepatotoxic regioisomer, 3'-hydroxyacetanilide, in mouse liver.
Topics: Acetaminophen; Acetanilides; Analgesics; Animals; Calcium; Calcium-Transporting ATPases; Cell Membrane; Glutathione; Glutathione Disulfide; Homeostasis; Isomerism; Kinetics; Liver; Male; Mice; Mitochondria, Liver; Reference Values; Subcellular Fractions | 1989 |
Effect of acetaminophen on hepatic content and biliary efflux of glutathione disulfide in mice.
Topics: Acetaminophen; Animals; Bile; Glutathione; Glutathione Disulfide; Liver; Male; Maleates; Mice; Mice, Inbred ICR | 1989 |
The generation and subsequent fate of glutathionyl radicals in biological systems.
Topics: Acetaminophen; Acetylcysteine; Chromatography, High Pressure Liquid; Cyclic N-Oxides; Cysteine; Electron Spin Resonance Spectroscopy; Free Radicals; Glutathione; Glutathione Disulfide; Horseradish Peroxidase; Nitrogen; Oxygen; Phenetidine; Spin Labels | 1985 |
Cytochrome P-450-mediated oxidation of substrates by electron-transfer; role of oxygen radicals and of 1- and 2-electron oxidation of paracetamol.
Topics: Acetaminophen; Animals; Cytochrome P-450 Enzyme System; Electron Transport; Free Radicals; Glutathione; Glutathione Disulfide; Male; Methylcholanthrene; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygen; Pyridines; Rats; Rats, Inbred Strains | 1988 |
The spontaneous and enzymatic reaction of N-acetyl-p-benzoquinonimine with glutathione: a stopped-flow kinetic study.
Topics: Acetaminophen; Animals; Benzoquinones; Glutathione; Glutathione Disulfide; Glutathione Transferase; Humans; Imines; Isoenzymes; Kinetics; Rats; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1988 |
Quinone imines as biological reactive intermediates.
Topics: Acetaminophen; Animals; Benzoquinones; Biotransformation; Dithiothreitol; Glutathione; Glutathione Disulfide; Imines; In Vitro Techniques; Kinetics; Liver; Oxidation-Reduction; Quinones | 1986 |
Glutathione oxidation during peroxidase catalysed drug metabolism.
Topics: Acetaminophen; Aminophenols; Aminopyrine; Dopamine; Glutathione; Glutathione Disulfide; Horseradish Peroxidase; Methyldopa; Oxidation-Reduction; Oxygen Consumption; Peroxidases; Pharmaceutical Preparations; Phenetidine; Phenothiazines; Sulfides; Superoxide Dismutase | 1987 |
Prostaglandin synthase catalyzed metabolic activation of p-phenetidine and acetaminophen by microsomes isolated from rabbit and human kidney.
Topics: Acetaminophen; Aminophenols; Animals; Arachidonic Acid; Arachidonic Acids; Glutathione; Glutathione Disulfide; Humans; Indomethacin; Kidney; Kinetics; Linolenic Acids; Lipid Peroxides; Male; Metyrapone; Microsomes; Models, Chemical; NADP; Phenetidine; Proadifen; Prostaglandin-Endoperoxide Synthases; Protein Binding; Rabbits | 1985 |
Plasma glutathione and glutathione disulfide in the rat: regulation and response to oxidative stress.
Topics: Acetaminophen; Animals; Diquat; Glutathione; Glutathione Disulfide; Inactivation, Metabolic; Liver; Lung; Male; Maleates; Paraquat; Peroxides; Rats; Rats, Inbred Strains; tert-Butylhydroperoxide | 1983 |
Biliary excretion of glutathione and glutathione disulfide in the rat. Regulation and response to oxidative stress.
Topics: Acetaminophen; Animals; Bile; Diquat; Free Radicals; Glutathione; Glutathione Disulfide; Liver; Male; Oxidation-Reduction; Peroxides; Rats; Rats, Inbred Strains; Sulfobromophthalein; tert-Butylhydroperoxide | 1984 |
Alkylation and peroxidation injury from chemically reactive metabolites.
Topics: Acetaminophen; Acetylcysteine; Alkylation; Animals; Antioxidants; Biotransformation; Drug-Related Side Effects and Adverse Reactions; Glutathione; Glutathione Disulfide; Humans; Lipid Peroxides; Liver; Microsomes, Liver; Peroxides; Pharmaceutical Preparations; Vitamin E | 1981 |
Oxidative stress by acute acetaminophen administration in mouse liver.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Dose-Response Relationship, Drug; Female; Glutathione; Glutathione Disulfide; Hydrogen Peroxide; Kinetics; L-Lactate Dehydrogenase; Liver; Luminescent Measurements; Mice; Oxidative Stress; Reactive Oxygen Species; Superoxides | 1995 |
A microtiter plate assay for total glutathione and glutathione disulfide contents in cultured/isolated cells: performance study of a new miniaturized protocol.
Topics: Acetaminophen; Animals; Cell Extracts; Cells, Cultured; Dithionitrobenzoic Acid; Extracellular Space; Glutathione; Glutathione Disulfide; Glutathione Reductase; Liver; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Vitamin K | 1994 |
[Cytoprotective effect of neurotensin on acetaminophen induced liver injury in relation to glutathione system].
Topics: Acetaminophen; Animals; Cells, Cultured; Chemical and Drug Induced Liver Injury; DNA; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Liver; Male; Mice; Neurotensin | 1994 |
Oxidative stress in cultured hepatocytes exposed to acetaminophen.
Topics: Acetaminophen; Animals; Carmustine; Cells, Cultured; Deferoxamine; Glutathione; Glutathione Disulfide; Liver; Male; Mice | 1993 |
Acetaminophen toxicity. Opposite effects of two forms of glutathione peroxidase.
Topics: Acetaminophen; Animals; Benzoquinones; Glutathione Disulfide; Glutathione Peroxidase; Humans; Imines; Isoenzymes; Lipid Peroxidation; Liver; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Oxidation-Reduction; Superoxide Dismutase | 1999 |
Prevention of acetaminophen-induced liver toxicity by 2(R,S)-n-propylthiazolidine-4(R)-carboxylic acid in mice.
Topics: Acetaminophen; Aldehydes; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Cysteine; Dose-Response Relationship, Drug; Drug Interactions; Glutathione; Glutathione Disulfide; Liver; Liver Diseases; Male; Mice; Mice, Inbred C57BL; Prodrugs; Protective Agents; Thiazoles | 2001 |
p-Aminophenol-induced liver toxicity: tentative evidence of a role for acetaminophen.
Topics: Acetaminophen; Acetylation; Alanine Transaminase; Aminophenols; Animals; Ascorbic Acid; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Cysteine; Cystine; Dose-Response Relationship, Drug; Drug Synergism; Glutathione; Glutathione Disulfide; L-Iditol 2-Dehydrogenase; Liver; Male; Mice; Mice, Inbred C57BL | 2001 |
Therapeutic effect of S-allylmercaptocysteine on acetaminophen-induced liver injury in mice.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Cysteine; Cytochrome P-450 CYP2E1; Glutathione; Glutathione Disulfide; HSP70 Heat-Shock Proteins; Liver; Male; Mice; Protective Agents | 2001 |
Scavenging peroxynitrite with glutathione promotes regeneration and enhances survival during acetaminophen-induced liver injury in mice.
Topics: Acetaminophen; Animals; Disease Models, Animal; Glutathione; Glutathione Disulfide; Immunohistochemistry; Liver Regeneration; Male; Mice; Mice, Inbred C3H; Peroxynitrous Acid; Respiratory Distress Syndrome; Survival Rate | 2003 |
Acetaminophen toxicity in mice lacking NADPH oxidase activity: role of peroxynitrite formation and mitochondrial oxidant stress.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Endothelium, Vascular; Glutathione; Glutathione Disulfide; Hepatocytes; Hydrogen Peroxide; Macrophages; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria, Liver; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Peroxynitrous Acid; Superoxides; Tyrosine | 2003 |
Involvement of mitochondrial permeability transition in acetaminophen-induced liver injury in mice.
Topics: Acetaminophen; Adenosine Triphosphate; Animals; Benzoquinones; Calcium; Cyclosporine; Glutathione Disulfide; Imines; Liver; Male; Membrane Potentials; Mice; Mitochondria, Liver; Permeability | 2005 |
Evaluation of oxidative status in acetaminophen treated rat hepatocytes in culture.
Topics: Acetaminophen; Albumins; Analgesics, Non-Narcotic; Animals; Cells, Cultured; Glutathione; Glutathione Disulfide; Hepatocytes; Male; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species | 2009 |
Comparison of the protective actions of N-acetylcysteine, hypotaurine and taurine against acetaminophen-induced hepatotoxicity in the rat.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Glutathione Transferase; Humans; Liver; Liver Diseases; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Taurine | 2010 |
The impact of partial manganese superoxide dismutase (SOD2)-deficiency on mitochondrial oxidant stress, DNA fragmentation and liver injury during acetaminophen hepatotoxicity.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; DNA Fragmentation; Drug Overdose; Glutathione; Glutathione Disulfide; In Situ Nick-End Labeling; JNK Mitogen-Activated Protein Kinases; Male; Mice; Mice, Inbred C57BL; Mitochondria, Liver; Necrosis; Oxidative Stress; Signal Transduction; Superoxide Dismutase | 2011 |
Apoptosis-inducing factor modulates mitochondrial oxidant stress in acetaminophen hepatotoxicity.
Topics: Acetaminophen; Animals; Apoptosis Inducing Factor; Blotting, Western; Chemical and Drug Induced Liver Injury; DNA Fragmentation; Drug Overdose; Glutathione Disulfide; Hepatocytes; Immunohistochemistry; In Situ Nick-End Labeling; Liver; Male; Mice; Mitochondria, Liver; Necrosis; Oxidative Stress; Peroxynitrous Acid; Reactive Oxygen Species | 2011 |
Susceptibility of rat non-alcoholic fatty liver to the acute toxic effect of acetaminophen.
Topics: Acetaminophen; Animals; Biomarkers; Caspase 3; Chemical and Drug Induced Liver Injury; Cholesterol; Disease Models, Animal; Disease Susceptibility; Electron Transport Chain Complex Proteins; Fatty Liver; Glutathione; Glutathione Disulfide; Liver; Male; Malondialdehyde; Necrosis; Non-alcoholic Fatty Liver Disease; Rats; Rats, Sprague-Dawley; Risk Factors; Severity of Illness Index; Time Factors; Transforming Growth Factor beta1; Triglycerides; Tumor Necrosis Factor-alpha | 2012 |
Changes in mouse liver protein glutathionylation after acetaminophen exposure.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Glutathione; Glutathione Disulfide; Hepatocytes; Liver; Male; Mice; Mice, Inbred Strains; Necrosis; Protein Processing, Post-Translational; Proteins | 2012 |
Reduction of acute hepatic damage induced by acetaminophen after treatment with diphenyl diselenide in mice.
Topics: Acetaminophen; Analysis of Variance; Animals; Benzene Derivatives; Catalase; Cell Survival; Glutathione; Glutathione Disulfide; Histocytochemistry; Liver; Liver Failure, Acute; Male; Mice; Organoselenium Compounds; Oxidative Stress; Peroxidase; Protective Agents; Reactive Oxygen Species; Thiobarbituric Acid Reactive Substances | 2012 |
Protective effects of 5-methoxypsoralen against acetaminophen-induced hepatotoxicity in mice.
Topics: 5-Methoxypsoralen; Acetaminophen; Administration, Oral; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Biomarkers; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Glutathione; Glutathione Disulfide; L-Lactate Dehydrogenase; Liver; Male; Malondialdehyde; Methoxsalen; Mice; Mice, Inbred C57BL; Oxidative Stress | 2012 |
Enhancement of acetaminophen-induced chronic hepatotoxicity in restricted fed rats: a nonclinical approach to acetaminophen-induced chronic hepatotoxicity in susceptible patients.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Antipyretics; Blood Glucose; Chemical and Drug Induced Liver Injury; Creatine; Creatinine; Diet; Glutathione; Glutathione Disulfide; Lactic Acid; Male; Malnutrition; Nutritional Status; Pyruvic Acid; Rats; Risk Factors; Taurine | 2012 |
Ratios of biliary glutathione disulfide (GSSG) to glutathione (GSH): a potential index to screen drug-induced hepatic oxidative stress in rats and mice.
Topics: Acetaminophen; Animals; Bile; Diquat; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Glutathione Disulfide; Liver; Male; Mice; Oxidation-Reduction; Oxidative Stress; Paraquat; Pharmaceutical Preparations; Rats; Rats, Sprague-Dawley; tert-Butylhydroperoxide | 2013 |
Comparative evaluation of the effects of taurine and thiotaurine on alterations of the cellular redox status and activities of antioxidant and glutathione-related enzymes by acetaminophen in the rat.
Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Catalase; Glutamate-Cysteine Ligase; Glutathione; Glutathione Disulfide; Glutathione Reductase; Glutathione Transferase; L-Lactate Dehydrogenase; Liver; Male; Malondialdehyde; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Taurine | 2013 |
Comparison of inhibitory effects between acetaminophen-glutathione conjugate and reduced glutathione in human glutathione reductase.
Topics: Acetaminophen; Dose-Response Relationship, Drug; Erythrocytes; Glutathione; Glutathione Disulfide; Glutathione Reductase; Humans; Recombinant Proteins | 2014 |
Role of connexin 32 in acetaminophen toxicity in a knockout mice model.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Connexins; Dose-Response Relationship, Drug; Gap Junction beta-1 Protein; Glutathione; Glutathione Disulfide; Immunohistochemistry; Liver; Liver Function Tests; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Necrosis | 2014 |
Thymoquinone treatment against acetaminophen-induced hepatotoxicity in rats.
Topics: Acetaminophen; Animals; Antioxidants; Benzoquinones; Chemical and Drug Induced Liver Injury; Glutathione Disulfide; Oxidoreductases; Rats; Rats, Wistar | 2014 |
Hepatoprotective and anti-oxidant activities of Glossogyne tenuifolia against acetaminophen-induced hepatotoxicity in mice.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Antioxidants; Antipyretics; Aspartate Aminotransferases; Asteraceae; Biomarkers; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Overdose; Glutathione; Glutathione Disulfide; Lipid Peroxidation; Liver; Male; Mice, Inbred BALB C; Phytotherapy; Plant Extracts | 2014 |
Inhibitor of apoptosis signal-regulating kinase 1 protects against acetaminophen-induced liver injury.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Glutathione; Glutathione Disulfide; JNK Mitogen-Activated Protein Kinases; Liver; Male; MAP Kinase Kinase Kinase 5; Mice, Inbred C57BL; Protective Agents; Protein Kinase Inhibitors | 2015 |
Connexin32: a mediator of acetaminophen-induced liver injury?
Topics: Acetaminophen; Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Connexins; Cytokines; Gap Junction beta-1 Protein; Glutathione Disulfide; Liver; Male; Mice, Inbred C57BL; Mice, Knockout; Proliferating Cell Nuclear Antigen; Protein Binding | 2016 |
Hearing, reactive metabolite formation, and oxidative stress in cochleae after a single acute overdose of acetaminophen: an in vivo study.
Topics: Acetaminophen; Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cochlea; Drug Overdose; Glutathione Disulfide; Hearing; Male; Mice, Inbred C57BL; Oxidative Stress; Protein Binding | 2016 |
Polydatin protects against acetaminophen-induced hepatotoxicity in mice via anti-oxidative and anti-apoptotic activities.
Topics: Acetaminophen; Alanine Transaminase; Animals; Antioxidants; Apoptosis; Apoptotic Protease-Activating Factor 1; Aspartate Aminotransferases; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Chemical and Drug Induced Liver Injury; Glucosides; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Hepatocytes; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; NADPH Oxidase 2; Nitric Oxide Synthase Type II; Oxidative Stress; Protective Agents; Reactive Oxygen Species; Stilbenes | 2018 |