Compounds > acetaminophen

acetaminophen and doxapram

acetaminophen has been researched along with doxapram in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's2 (28.57)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Glen, RC; Lowe, R; Mitchell, JB1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Ishikawa, M; Kanno, S; Sasaki, K; Takayanagi, M; Takayanagi, Y2
Ishikawsa, M; Kanno, S; Sasaki, K; Takayanagi, M; Takayanagi, Y1

Reviews

1 review(s) available for acetaminophen and doxapram

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

6 other study(ies) available for acetaminophen and doxapram

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Potentiation of acetaminophen hepatotoxicity and mortality by doxapram in mice.
    Biological & pharmaceutical bulletin, 1998, Volume: 21, Issue:9

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Central Nervous System Stimulants; Chemical and Drug Induced Liver Injury; Doxapram; Drug Synergism; Male; Mice; Respiratory System Agents

1998
Combination acetaminophen and doxapram potentiated hepatotoxicity in mouse primary cultured hepatocytes.
    Methods and findings in experimental and clinical pharmacology, 1999, Volume: 21, Issue:10

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Antioxidants; Apoptosis; Calcium; Cell Survival; Cells, Cultured; Central Nervous System Stimulants; Chemical and Drug Induced Liver Injury; DNA Fragmentation; Doxapram; Drug Synergism; Electrophoresis, Agar Gel; Fluorescent Dyes; Iron; Lipid Peroxidation; Liver; Male; Malondialdehyde; Mice; Mice, Inbred C57BL

1999
Potentiation of acetaminophen hepatotoxicity by doxapram in mouse primary cultured hepatocytes.
    Biological & pharmaceutical bulletin, 2000, Volume: 23, Issue:4

    Topics: Acetaminophen; Animals; Caspase Inhibitors; Cells, Cultured; Cysteine Proteinase Inhibitors; DNA Fragmentation; Doxapram; Drug Synergism; Liver; Male; Mice; Mice, Inbred C57BL; Oxidative Stress

2000