acetaminophen and dithiothreitol

acetaminophen has been researched along with dithiothreitol in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19907 (50.00)18.7374
1990's7 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lauriault, VV; O'Brien, PJ1
Boobis, AR; Davies, DS; Nasseri-Sina, P; Seddon, CE1
Cotgreave, IA; Harvison, PJ; Moldéus, P; Nelson, SD; Porubek, DJ; Rundgren, M1
Harvison, PJ; Moldéus, P; Nelson, SD; Porubek, DJ; Rundgren, M1
Harman, AW; Self, G1
Albano, E; Larsson, R; Moldéus, P; Nelson, SD; Porubek, D; Ross, D; Rundgren, M1
Boobis, AR; Davies, DS; Hampden, C; Tee, LB1
Boobis, AR; Davies, DS; Huggett, AC; Tee, LB1
Albano, E; Harvison, PJ; Moldéus, P; Nelson, SD; Rundgren, M1
Barr, SG; Harrison, JJ; Racz, WJ; Rafeiro, E1
Grewal, KK; Racz, WJ1
Aniya, Y; Koyama, T; Nagamine, T; Nakanishi, H; Yokomakura, T; Yonamine, M1
Agudo, A; Cameselle, JC; Costas, MJ; Ribeiro, JM1
Cameselle, JC; Costas, MJ; Ribeiro, JM1

Other Studies

14 other study(ies) available for acetaminophen and dithiothreitol

ArticleYear
Molecular mechanism for prevention of N-acetyl-p-benzoquinoneimine cytotoxicity by the permeable thiol drugs diethyldithiocarbamate and dithiothreitol.
    Molecular pharmacology, 1991, Volume: 40, Issue:1

    Topics: Acetaminophen; Alkylation; Animals; Benzoquinones; Cell Survival; Dithiothreitol; Ditiocarb; Glutathione; Imines; Liver; Male; Oxidation-Reduction; Rats; Rats, Inbred Strains

1991
Evidence for a direct role of intracellular calcium in paracetamol toxicity.
    Biochemical pharmacology, 1990, Apr-15, Volume: 39, Issue:8

    Topics: Acetaminophen; Aminoquinolines; Animals; Calcium; Cell Membrane; Cell Survival; Chelating Agents; Cricetinae; Cytosol; Dithiothreitol; In Vitro Techniques; Liver; Male; Mesocricetus

1990
Comparative cytotoxic effects of N-acetyl-p-benzoquinone imine and two dimethylated analogues.
    Molecular pharmacology, 1988, Volume: 34, Issue:4

    Topics: Acetaminophen; Animals; Benzoquinones; Carmustine; Cell Survival; Chemical Phenomena; Chemistry; Deferoxamine; Dithiothreitol; Dose-Response Relationship, Drug; Glutathione; Imines; Lipid Peroxides; Liver; Oxidation-Reduction; Oxygen; Rats; Structure-Activity Relationship

1988
Investigation of mechanisms of acetaminophen toxicity in isolated rat hepatocytes with the acetaminophen analogues 3,5-dimethylacetaminophen and 2,6-dimethylacetaminophen.
    Molecular pharmacology, 1987, Volume: 31, Issue:6

    Topics: Acetaminophen; Animals; Carmustine; Dithiothreitol; Glutathione; Glutathione Reductase; In Vitro Techniques; Kinetics; Lipid Peroxides; Liver; Male; Maleates; Rats; Rats, Inbred Strains

1987
Comparison of the protective effects of N-acetylcysteine, 2-mercaptopropionylglycine and dithiothreitol against acetaminophen toxicity in mouse hepatocytes.
    Toxicology, 1986, Volume: 41, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Amino Acids, Sulfur; Animals; Cells, Cultured; Dithiothreitol; Glutathione; Liver; Male; Mice; Tiopronin

1986
Quinone imines as biological reactive intermediates.
    Advances in experimental medicine and biology, 1986, Volume: 197

    Topics: Acetaminophen; Animals; Benzoquinones; Biotransformation; Dithiothreitol; Glutathione; Glutathione Disulfide; Imines; In Vitro Techniques; Kinetics; Liver; Oxidation-Reduction; Quinones

1986
Acetaminophen toxicity in isolated hepatocytes.
    Advances in experimental medicine and biology, 1986, Volume: 197

    Topics: Acetaminophen; Animals; Cell Survival; Dithiothreitol; Guinea Pigs; Kinetics; Liver

1986
Reversal of acetaminophen toxicity in isolated hamster hepatocytes by dithiothreitol.
    Toxicology and applied pharmacology, 1986, Volume: 83, Issue:2

    Topics: Acetaminophen; Animals; Antidotes; Benzoquinones; Carbon Radioisotopes; Cell Survival; Cricetinae; Dithiothreitol; Drug Interactions; Glutathione; Imines; In Vitro Techniques; Lipid Peroxides; Liver; Male; Mesocricetus; Microscopy, Electron, Scanning

1986
Mechanisms of N-acetyl-p-benzoquinone imine cytotoxicity.
    Molecular pharmacology, 1985, Volume: 28, Issue:3

    Topics: Acetaminophen; Animals; Benzoquinones; Cell Survival; Dithiothreitol; Glutathione; Imines; In Vitro Techniques; Liver; Male; NADP; Rats; Rats, Inbred Strains

1985
Effects of N-acetylcysteine and dithiothreitol on glutathione and protein thiol replenishment during acetaminophen-induced toxicity in isolated mouse hepatocytes.
    Toxicology, 1994, Nov-11, Volume: 93, Issue:2-3

    Topics: Acetaminophen; Acetylcysteine; Animals; Buthionine Sulfoximine; Dithiothreitol; Glutathione; L-Lactate Dehydrogenase; Liver; Male; Methionine Sulfoximine; Mice; Sulfhydryl Compounds

1994
Intracellular calcium disruption as a secondary event in acetaminophen-induced hepatotoxicity.
    Canadian journal of physiology and pharmacology, 1993, Volume: 71, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Animals; Calcium; Cell Membrane; Chelating Agents; Chemical and Drug Induced Liver Injury; Dithiothreitol; Fura-2; In Vitro Techniques; Male; Mice; Sulfhydryl Compounds

1993
Acetaminophen-derived activation of liver microsomal glutathione S-transferase of rats.
    Japanese journal of pharmacology, 1996, Volume: 72, Issue:2

    Topics: Acetaminophen; Animals; Dithiothreitol; Dose-Response Relationship, Drug; Enzyme Activation; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Sulfhydryl Reagents; Time Factors

1996
Rat liver ADP-ribose pyrophosphatase-I as an in vitro target of the acetaminophen metabolite N-acetyl-p-benzoquinoneimine.
    Biochimica et biophysica acta, 1997, Oct-20, Volume: 1336, Issue:3

    Topics: Acetaminophen; Animals; Benzoquinones; Chromatography, Gel; Cytosol; Dithiothreitol; Imines; Kinetics; Liver; Pyrophosphatases; Rats

1997
ADP-ribose pyrophosphatase-I partially purified from livers of rats overdosed with acetaminophen reveals enzyme inhibition in vivo reverted in vitro by dithiothreitol.
    Journal of biochemical and molecular toxicology, 1999, Volume: 13, Issue:3-4

    Topics: Acetaminophen; Animals; Dithiothreitol; Enzyme Inhibitors; Enzyme Reactivators; Female; Liver; Pyrophosphatases; Rats; Rats, Wistar

1999