acetaminophen and diphenhydramine hydrochloride

acetaminophen has been researched along with diphenhydramine hydrochloride in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19908 (23.53)18.7374
1990's0 (0.00)18.2507
2000's13 (38.24)29.6817
2010's12 (35.29)24.3611
2020's1 (2.94)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Emele, JF; Ramachander, G; Williams, FD1
Doyle, TD; Levine, J1
Heveran, JE; Mahn, FP; Menyharth, A1
Grimshaw, JJ; Jaffé, G1
Carnevale, L1
McSharry, WO; Savage, IV1
Gunn, VL; Liebelt, EL; Serwint, JR; Taha, SH1
Baker, SD; Borys, DJ1
HARRIS, LE; POGGE, RC1
AVIADO, DM; SALEM, H1
Carrére, C; Casassus-Builhé, D; Rey, P1
Miller, SC1
Schwartz, RH1
Belhassen García, M; Carpio Pérez, A; Geijo Martínez, F; Prieto Vicente, V; Sánchez Martín, F1
Otsuka, M; Sakata, Y; Shiraishi, S; Sumikawa, T; Tanabe, E; Tokudome, Y1
Chmara, ES; Collins, GL; Mundy, LA; Wingert, WE1
Chen, H; Chen, X; Liu, L; Liu, X1
Goodale, M; Grender, JM; Hull, JD; Jerdack, GR; Mizoguchi, H; Tyler, BA; Wilson, A1
Callesen, T; Gärtner, R; Kehlet, H; Kroman, N1
Chen, X; Liu, X; Zhang, J1
Hendrickson, RG1
Butt, S; Dargan, PI; English, E; Garnham, F; Ovaska, H; Wood, DM1
McGettigan, P; Waring, WS1
Katoh, N; Nakai, N; Yokose, C1
Allan, GM; Arroll, B1
Broekhuizen, BD; Butler, CC; Coenen, S; Francis, NA; Goossens, H; Hamoen, M; Little, P; Melbye, H; Verheij, TJ1
Han, N; Liu, Z; Wang, J; Wang, Y; Yin, J1
Bellosta, E; Iñiguez, C; Santos, S; Velázquez, A1
Essam, HM; Yehia, AM1
Mallefet, P; Zhang, Y1
Burnham, RI; Delva-Clark, H; Green, JL; Paul, IM; Reynolds, KM1
Abboushi, EK; Hammoudeh, AY; Mahmoud, AM; Obeidat, SM1

Reviews

4 review(s) available for acetaminophen and diphenhydramine hydrochloride

ArticleYear
ANTITUSSIVE DRUGS, WITH SPECIAL REFERENCE TO A NEW THEORY FOR THE INITATION OF THE COUGH REFLEX AND THE INFLUENCE OR BRONCHODILATORS.
    The American journal of the medical sciences, 1964, Volume: 247

    Topics: Acetaminophen; Aerosols; Aminophylline; Analgesics; Analgesics, Non-Narcotic; Animals; Antimony; Antipyretics; Antitussive Agents; Ascorbic Acid; Bronchodilator Agents; Caffeine; Codeine; Cough; Dogs; Electric Stimulation; Electrophysiology; Expectorants; Histamine H1 Antagonists; Hypnotics and Sedatives; Ion Exchange Resins; Noscapine; Parasympatholytics; Pharmacology; Phenothiazines; Promethazine; Reflex; Research; Sodium Salicylate; Sympathomimetics

1964
Adolescent abuse of dextromethorphan.
    Clinical pediatrics, 2005, Volume: 44, Issue:7

    Topics: Acetaminophen; Adolescent; Antitussive Agents; Chlorpheniramine; Dextromethorphan; Drug Combinations; Humans; Nonprescription Drugs; Phenylpropanolamine; Substance-Related Disorders

2005
Prevention and treatment of the common cold: making sense of the evidence.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2014, Feb-18, Volume: 186, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antitussive Agents; Ascorbic Acid; Cholinergic Antagonists; Common Cold; Dietary Supplements; Drug Combinations; Echinacea; Exercise Therapy; Garlic; Hand Disinfection; Histamine Antagonists; Honey; Humans; Ipratropium; Nasal Decongestants; Panax; Plant Extracts; Probiotics; Terpenes; Vitamin D; Zinc

2014
Medication use in European primary care patients with lower respiratory tract infection: an observational study.
    The British journal of general practice : the journal of the Royal College of General Practitioners, 2014, Volume: 64, Issue:619

    Topics: Acetaminophen; Adult; Anti-Bacterial Agents; Antitussive Agents; Europe; Expectorants; Female; Humans; Logistic Models; Male; Middle Aged; Practice Patterns, Physicians'; Primary Health Care; Referral and Consultation; Respiratory Tract Infections; Self Medication; Severity of Illness Index

2014

Trials

3 trial(s) available for acetaminophen and diphenhydramine hydrochloride

ArticleYear
Randomized single-blind trial in general practice comparing the efficacy and palatability of two cough linctus preparations, 'Pholcolix' and 'Actifed' Compound, in children with acute cough.
    Current medical research and opinion, 1983, Volume: 8, Issue:8

    Topics: Acetaminophen; Antitussive Agents; Child; Codeine; Cough; Drug Combinations; Ephedrine; Female; Humans; Male; Patient Acceptance of Health Care; Phenylpropanolamine; Pseudoephedrine; Pyridines; Random Allocation; Sleep Stages; Triprolidine

1983
Efficacy of a single evening dose of syrup containing paracetamol, dextromethorphan hydrobromide, doxylamine succinate and ephedrine sulfate in subjects with multiple common cold symptoms.
    International journal of clinical pharmacology and therapeutics, 2007, Volume: 45, Issue:4

    Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Antitussive Agents; Bronchodilator Agents; Common Cold; Dextromethorphan; Double-Blind Method; Doxylamine; Drug Combinations; Ephedrine; Female; Histamine H1 Antagonists; Humans; Male; Middle Aged; Prospective Studies; Sleep Wake Disorders

2007
Time-to-onset of cold and flu symptom relief: A randomized, double-blind, placebo-controlled pilot study for a multi-symptom combination product.
    International journal of clinical pharmacology and therapeutics, 2018, Volume: 56, Issue:12

    Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Antitussive Agents; China; Chlorpheniramine; Common Cold; Dextromethorphan; Double-Blind Method; Drug Combinations; Female; Histamine H1 Antagonists; Humans; Influenza, Human; Male; Middle Aged; Nasal Decongestants; Patient Satisfaction; Pilot Projects; Pseudoephedrine; Remission Induction; Tablets; Time Factors; Treatment Outcome

2018

Other Studies

27 other study(ies) available for acetaminophen and diphenhydramine hydrochloride

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Effect of salicylamide and acetaminophen on dextromethorphan hydrobromide metabolism: possible pharmacological implications.
    Journal of pharmaceutical sciences, 1978, Volume: 67, Issue:6

    Topics: Acetaminophen; Animals; Antitussive Agents; Dextromethorphan; Dextrorphan; Dogs; Drug Interactions; Female; Levorphanol; Rats; Salicylamides; Time Factors

1978
Determination of phenylephrine in combinations with other drugs.
    Journal of pharmaceutical sciences, 1967, Volume: 56, Issue:5

    Topics: Acetaminophen; Antitussive Agents; Aspirin; Chlorpheniramine; Chromatography; Dosage Forms; Expectorants; Guaifenesin; Histamine H1 Antagonists; Magnesium; Phenolphthaleins; Phenylephrine; Phenylpropanolamine; Solutions; Sympathomimetics; Tablets; Ultraviolet Rays

1967
Rapid quantitative determination of three active ingredients in liquid antitussive preparations by high-speed liquid chromatography.
    Journal of pharmaceutical sciences, 1974, Volume: 63, Issue:3

    Topics: Acetaminophen; Antitussive Agents; Chromatography; Dextromethorphan; Dibenzazepines; Indicators and Reagents; Methods; Spectrophotometry, Ultraviolet; Time Factors

1974
Simultaneous determination of acetaminophen, guaifenesin, pseudoephedrine, pholcodine, and paraben preservatives in cough mixture by high-performance liquid chromatography.
    Journal of pharmaceutical sciences, 1983, Volume: 72, Issue:2

    Topics: Acetaminophen; Antitussive Agents; Chromatography, High Pressure Liquid; Codeine; Drug Combinations; Ephedrine; Guaifenesin; Morpholines; Parabens

1983
Simultaneous high-pressure liquid chromatographic determination of acetaminophen, guaifenesin, and dextromethorphan hydrobromide in cough syrup.
    Journal of pharmaceutical sciences, 1980, Volume: 69, Issue:2

    Topics: Acetaminophen; Antitussive Agents; Chromatography, High Pressure Liquid; Dextromethorphan; Drug Combinations; Guaifenesin; Levorphanol; Methods

1980
Toxicity of over-the-counter cough and cold medications.
    Pediatrics, 2001, Volume: 108, Issue:3

    Topics: Acetaminophen; Antitussive Agents; Bradycardia; Brompheniramine; Cardiovascular Diseases; Child, Preschool; Drug Combinations; Drug Overdose; Fatal Outcome; Fever; Heart Arrest; Humans; Hypertension; Ibuprofen; Male; Nonprescription Drugs; Phenylephrine; Phenylpropanolamine; Pseudoephedrine; Sleep Stages; Tachycardia; Vomiting

2001
A possible trend suggesting increased abuse from Coricidin exposures reported to the Texas Poison Network: comparing 1998 to 1999.
    Veterinary and human toxicology, 2002, Volume: 44, Issue:3

    Topics: Acetaminophen; Adolescent; Adolescent Behavior; Age Factors; Antitussive Agents; Child; Chlorpheniramine; Databases, Factual; Dextromethorphan; Drug Combinations; Drug Overdose; Female; Humans; Incidence; Male; Medical Records; Nonprescription Drugs; Phenylpropanolamine; Population Surveillance; Retrospective Studies; Texas

2002
TIMED-RELEASE TABLETS: DEMONSTRATION OF MECHANISM IN HUMAN SUBJECTS.
    The Nebraska state medical journal, 1964, Volume: 49

    Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Anti-Allergic Agents; Antipyretics; Antitussive Agents; Biomedical Research; Delayed-Action Preparations; Histamine H1 Antagonists; Hydrocortisone; Pheniramine; Phenylpropanolamine; Scopolamine; Sympathomimetics; Tablets

1964
[Association of paracetamol and codeine, a rare cause of acute drug-induced pancreatitis].
    Presse medicale (Paris, France : 1983), 2004, Apr-24, Volume: 33, Issue:8

    Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Antitussive Agents; Codeine; Humans; Male; Pancreatitis

2004
Coricidin HBP cough and cold addiction.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2005, Volume: 44, Issue:6

    Topics: Acetaminophen; Adolescent; Animals; Antitussive Agents; Chlorpheniramine; Dextromethorphan; Drug Combinations; Humans; Male; Nonprescription Drugs; Phenylpropanolamine; Substance Abuse Detection; Substance Withdrawal Syndrome; Substance-Related Disorders

2005
[Pancreatitis due to acetaminophen-codeine].
    Anales de medicina interna (Madrid, Spain : 1984), 2006, Volume: 23, Issue:8

    Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Antitussive Agents; Codeine; Humans; Male; Middle Aged; Pancreatitis

2006
Effects of solid-state reaction between paracetamol and cloperastine hydrochloride on the pharmaceutical properties of their preparations.
    International journal of pharmaceutics, 2007, Apr-20, Volume: 335, Issue:1-2

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Antitussive Agents; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Crystallography, X-Ray; Drug Combinations; Drug Stability; Hardness; Hydrogen Bonding; Microscopy, Electron, Scanning; Phase Transition; Piperidines; Powders; Solubility; Spectroscopy, Fourier Transform Infrared; Tablets; Technology, Pharmaceutical; Temperature; Time Factors

2007
Possible role of pseudoephedrine and other over-the-counter cold medications in the deaths of very young children.
    Journal of forensic sciences, 2007, Volume: 52, Issue:2

    Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Antitussive Agents; Brompheniramine; Bronchodilator Agents; Cause of Death; Central Nervous System Depressants; Child; Child, Preschool; Chlorpheniramine; Common Cold; Databases as Topic; Dextromethorphan; Doxylamine; Ephedrine; Ethanol; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Histamine H1 Antagonists; Humans; Infant; Male; Nonprescription Drugs; Philadelphia; Pyridines

2007
Separation and determination of four active components in medicinal preparations by flow injection-capillary electrophoresis.
    Journal of pharmaceutical and biomedical analysis, 2007, Apr-11, Volume: 43, Issue:5

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Antitussive Agents; Bronchodilator Agents; Buffers; Chlorpheniramine; Common Cold; Dextromethorphan; Electrophoresis, Capillary; Ephedrine; Flow Injection Analysis; Histamine H1 Antagonists; Hydrogen-Ion Concentration; Maleates; Reproducibility of Results; Time Factors

2007
[Postoperative inconveniences after breast cancer surgery].
    Ugeskrift for laeger, 2008, Jun-02, Volume: 170, Issue:23

    Topics: Acetaminophen; Amines; Analgesics; Antiemetics; Antitussive Agents; Breast Neoplasms; Celecoxib; Cyclohexanecarboxylic Acids; Cyclooxygenase Inhibitors; Dexamethasone; Dextromethorphan; Droperidol; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Ondansetron; Pain, Postoperative; Postoperative Nausea and Vomiting; Pyrazoles; Sulfonamides

2008
Online concentration by head-column field-amplified with large-volume sample stacking using flow injection-capillary electrophoresis for the analysis of four active components in cold medicines.
    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2008, Volume: 24, Issue:8

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Allergic Agents; Antitussive Agents; Chlorpheniramine; Common Cold; Dextromethorphan; Electrophoresis, Capillary; Flow Injection Analysis; Nasal Decongestants; Pharmaceutical Preparations; Pseudoephedrine; Reproducibility of Results; Sensitivity and Specificity; Time Factors

2008
"DXemon juice:" analytical evaluation of an extraction process for the purification and freebasing of dextromethorphan from cold preparations.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2008, Volume: 4, Issue:4

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Antitussive Agents; Citrus; Crystallization; Dextromethorphan; Doxylamine; Drug Combinations; Gas Chromatography-Mass Spectrometry; Histamine H2 Antagonists; Illicit Drugs; Nasal Decongestants; Nonprescription Drugs; Pseudoephedrine; Solutions; Substance-Related Disorders

2008
Patient knowledge of the paracetamol content of over-the-counter (OTC) analgesics, cough/cold remedies and prescription medications.
    Emergency medicine journal : EMJ, 2010, Volume: 27, Issue:11

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Antitussive Agents; Female; Health Knowledge, Attitudes, Practice; Humans; London; Male; Maximum Tolerated Dose; Nonprescription Drugs; Prescription Drugs; Product Labeling; Surveys and Questionnaires

2010
Clinical toxicology and drug regulation: a United Kingdom perspective.
    Clinical toxicology (Philadelphia, Pa.), 2011, Volume: 49, Issue:6

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Antipsychotic Agents; Antitussive Agents; Cyclooxygenase 2 Inhibitors; Dextropropoxyphene; Drug Combinations; Drug Overdose; Humans; Lactones; Legislation, Drug; Poison Control Centers; Product Recalls and Withdrawals; Sulfones; Toxicology; United Kingdom

2011
Maculopapular-type drug eruption caused by Coughcode(®)-N combination tablets.
    Allergology international : official journal of the Japanese Society of Allergology, 2013, Volume: 62, Issue:4

    Topics: Acetaminophen; Administration, Oral; Adolescent; Antitussive Agents; Bromisovalum; Codeine; Diphenhydramine; Drug Combinations; Drug Eruptions; Dyphylline; Eosinophils; Ephedrine; Female; Humans; Immunization; Skin Tests; Tablets

2013
Three alkaloids from Reineckia carnea herba and their antitussive and expectorant activities.
    Natural product research, 2014, Volume: 28, Issue:16

    Topics: Alkaloids; Aminophenols; Antitussive Agents; Cough; Drugs, Chinese Herbal; Expectorants; Liliaceae; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Phenyl Ethers; Plant Roots; Propanols; Quaternary Ammonium Compounds

2014
Myoclonus secondary to use of anti-flu drug.
    Neurologia (Barcelona, Spain), 2017, Volume: 32, Issue:2

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Antitussive Agents; Dextromethorphan; Humans; Male; Middle Aged; Myoclonus

2017
Development and validation of a generic high-performance liquid chromatography for the simultaneous separation and determination of six cough ingredients: Robustness study on core-shell particles.
    Journal of separation science, 2016, Volume: 39, Issue:17

    Topics: Acetaminophen; Antitussive Agents; Chromatography, High Pressure Liquid; Dextromethorphan; Doxylamine; Ephedrine; Guaifenesin; Humans; Phenylephrine

2016
Flow Restrictors and Reduction of Accidental Ingestions of Over-the-Counter Medications.
    American journal of preventive medicine, 2019, Volume: 56, Issue:6

    Topics: Accidents; Acetaminophen; Age Factors; Antitussive Agents; Child, Preschool; Diphenhydramine; Drug Overdose; Drug Packaging; Female; Humans; Ibuprofen; Infant; Male; Nonprescription Drugs; Poison Control Centers; Seasons; United States

2019
FT-IR Spectroscopy for the Detection of Diethylene Glycol (DEG) Contaminant in Glycerin-Based Pharmaceutical Products and Food Supplements.
    Acta chimica Slovenica, 2020, Volume: 67, Issue:2

    Topics: Acetaminophen; Antitussive Agents; Dietary Supplements; Drug Contamination; Ethylene Glycols; Glycerol; Melissa; Spectroscopy, Fourier Transform Infrared; Stevia

2020