acetaminophen has been researched along with dinoprostone in 81 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 12 (14.81) | 18.7374 |
1990's | 22 (27.16) | 18.2507 |
2000's | 23 (28.40) | 29.6817 |
2010's | 22 (27.16) | 24.3611 |
2020's | 2 (2.47) | 2.80 |
Authors | Studies |
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Duffy, EM; Jorgensen, WL | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
Beaver, TH; Chan, KY; Diekema, KA; Dinerstein, RJ; Doherty, NS | 1 |
Berg, KJ; Djøseland, O; Gjellan, A; Hundal, O; Knudsen, ER; Rugstad, HE; Rønneberg, E | 1 |
Melendez, E; Reyes, JL | 1 |
Fontan, JE; Weber, B | 1 |
Connell, MJ; Ferrari, RA; Haubrich, DR; Perrone, MH; Van Liew, DK; Ward, SJ; Zobre, CM | 1 |
Manson, LM; Mattison, P; Menzies, DG; Prescott, LF | 1 |
Bippi, H; Frölich, JC | 1 |
Escalante, BA; Meléndez, E; Meléndez, MA; Reyes, JL | 1 |
Escalante, BA; Meléndez, E; Namorado, MC; Reyes, JL | 1 |
Ferreira, SH; Lorenzetti, BB | 1 |
Karmeli, F; Ligumsky, M; Rachmilewitz, D; Sestieri, M | 1 |
Ivey, KJ; Razandi, M; Romano, M | 1 |
Hiraishi, H; Ivey, KJ; Ota, S; Razandi, M; Sekhon, S; Terano, A | 1 |
Clark, WG; Holdeman, M; Lipton, JM | 1 |
Isomäki, H; Laitinen, O; Nissilä, M; Nuotio, P; Nykänen, E; Seppälä, E; Vapaatalo, H | 1 |
Brune, K; Peskar, BA | 1 |
Cinotti, GA | 1 |
Laitinen, O; Seppälä, E; Vapaatalo, H | 1 |
Hagelen, F; Van Kolfschoten, AA; Van Noordwijk, J | 1 |
Bilić, A; Culo, F; Jagić, V; Rados, M; Renić, M; Sabolović, D | 1 |
Abramson, SB; Amin, AR; Attur, M; Leszczynska-Piziak, J; Patel, IR; Vyas, P; Weissmann, G | 1 |
Itoh, T; Kamisaki, Y; Kawasaki, H; Omura, H | 1 |
Elias, MM; Monasterolo, LA; Ochoa, E; Trumper, L | 1 |
Martin, U; Prescott, LF | 1 |
Bilić, A; Bukovec, Z; Culo, F; Renić, M; Sabolović, D; Zupanović, Z | 1 |
Engelhardt, G | 1 |
Cohen, SM; Cowan, A; Kehoe, MJ; Zarrinnia, K | 1 |
Itoh, T; Kamisaki, Y; Kawasaki, H; Nakamoto, K; Wada, K | 1 |
Apicella, C; Brufani, M; Capezzone de Joannon, A; Coletta, I; Di Cesare, F; Landolfi, C; Milanese, C; Pinza, M; Polenzani, L; Soldo, L | 1 |
Colletti, AE; Rahe, T; Vogl, HW; Zambraski, EJ | 1 |
Farquhar, WB; Kenney, WL; Morgan, AL; Zambraski, EJ | 1 |
Brune, K; Geisslinger, G; Muth-Selbach, US; Tegeder, I | 1 |
Cook, ME; Thakur, V; Wallin, JD | 1 |
Housholder, G; Hutchins, M; Montgomery, E; Rittman, B; Rittman, G; Suchina, J | 1 |
Aicher, B; Engelhardt, G; Fiebich, BL; Hüll, M; Lieb, K; Pairet, M; van Ryn, J | 1 |
Evans, WJ; Fluckey, JD; Lambert, CP; Trappe, TA; White, F | 1 |
Bourdi, M; Brady, JN; George, JW; Marchick, MR; Pise-Masison, CA; Pohl, LR; Radonovich, MF; Reilly, TP | 1 |
Catella-Lawson, F; Cucchiara, AJ; DeMarco, S; FitzGerald, GA; Kapoor, SC; Reilly, MP; Tournier, B; Vyas, SN | 1 |
Aronoff, DM; Boutaud, O; Marnett, LJ; Oates, JA; Richardson, JH | 1 |
Di Massa, A; Frangov, P; Galunska, B; Krushkov, I; Marazova, K; Popov, A; Tankova, T | 1 |
Ajmone-Cat, MA; Greco, A; Minghetti, L; Nicolini, A; Sciulli, MG | 1 |
Goodin, MG; Rosengren, RJ; Walker, RJ | 1 |
Ayoub, SS; Ballou, LR; Botting, RM; Colville-Nash, PR; Goorha, S; Willoughby, DA | 1 |
Busija, DW; Kis, B; Simandle, SA; Snipes, JA | 1 |
Alexander, JP; Andersson, DA; Basbaum, AI; Björk, H; Cravatt, BF; Ermund, A; Högestätt, ED; Jönsson, BA; Zygmunt, PM | 1 |
Ayoub, SS; Botting, RM; Colville-Nash, PR; Willoughby, DA | 1 |
Brahim, JS; Dionne, RA; Kim, H; Lee, G; Lee, YS; Rowan, J | 1 |
Ceña, V; Posadas, I; Prieto-Lloret, J; Santos, P; Vellecco, V | 1 |
Mamuk, S; Melli, M | 1 |
Bianchi, M; Ferrario, P; Franchi, S; Martucci, C; Sacerdote, P | 1 |
Blatteis, CM; Feleder, C; Perlik, V | 2 |
Ballou, LR; Blatteis, CM; Dou, W; Goorha, S; Li, S; Tang, Y | 1 |
Brahim, JS; Chuang, BP; Dionne, RA; Gordon, SM; Hamza, MA; Rowan, JS; Wang, XM | 1 |
Crawley, B; Fitzsimmons, B; Hua, XY; Malkmus, S; Saito, O; Yaksh, TL | 1 |
Aguiar, FA; de Souza, GE; do Vale, ML; Kanashiro, A; Machado, RR; Malvar, Ddo C; Pessini, AC; Soares, DM | 1 |
Cavar, I; Culo, F; Kelava, T; Saraga-Babić, M; Vukojević, K | 1 |
Boutaud, O; Oates, JA | 1 |
Babu, IR; Goessling, W; Lord, AM; North, TE; Tannenbaum, SR; Vedder, LM; Wishnok, JS; Zon, LI | 1 |
Bhave, VS; Cunningham, ML; Donthamsetty, S; Latendresse, JR; Mehendale, HM | 1 |
Broadley, KJ; Clark, SR; Evans, RL; Gallimore, AM; Godkin, AJ; Hindley, JP; Jones, SA; Kidd, EJ; Lauder, SN; Leach, H; O'Donnell, V; Smart, K; Taylor, PR; Wise, MP | 1 |
Loewen, M; McEnulty, B; Rothenberg, SJ; Shanholtzer, L; Trinh, K; Walsh, P | 1 |
Brown, AT; Chaudhuri, S; Hennings, L; Hinson, JA; James, LP; Li, SH; McCullough, SS; Simpson, PM | 1 |
Blomqvist, A; Elander, L; Engblom, D; Engström Ruud, L; Eskilsson, A; Vasilache, AM; Wilhelms, DB | 1 |
Carroll, CC; Cauthon, DJ; Del Mundo, JD; Friedlander, GN; Gump, BS; Kim, PJ; Langberg, H; Letham, T; McMullan, DR; Pingel, J; Whitt, JA | 1 |
Bostanoglu, E; Demirbilek, M; Polat-Ozsoy, O; Tunçer, Z | 1 |
Ganeshkar, SV; Hegde, S; Patil, AK; Shetty, N | 1 |
Kannan, K; Kesavan, M; Sankar, P; Sarkar, SN; Suresh, S; Tandan, SK; Vijayakaran, K | 1 |
Kamarolzaman, MF; Kamisan, FH; Mahmood, ND; Mamat, SS; Mohtarrudin, N; Nasir, N; Tohid, SF; Yahya, F; Zakaria, ZA | 1 |
Bury, F; Chantrain, C; François-Adant, A; Langhendries, JP; Maton, P; Philippet, P | 1 |
Allegaert, K; Langhendries, JP; Smets, F; Van Den Anker, JN; Veyckemans, F | 1 |
Ao, T; Hangai, S; Kawamura, T; Kimura, Y; Kodama, T; Matsuki, K; Negishi, H; Nishio, J; Taniguchi, T; Yanai, H | 1 |
Amador-Noguez, D; Knoll, LJ; McDougal, CE; Nakanishi, M; Rosenberg, DW; Sauer, JD; Stevenson, DM; Theisen, E | 1 |
Blomgren, A; Blomqvist, A; Engblom, D; Högestätt, ED; Mirrasekhian, E; Nilsson, JLÅ; Shionoya, K; Zygmunt, PM | 1 |
Chen, Y; Chu, H; Gozali, L; Hung, IFN; Lee, ACY; Li, C; To, KKW; Yuen, KY; Zhang, AJX; Zhu, H | 1 |
Cheng, Y; Chowdhury, A; Jia, Z; Lu, J; Song, J; Sun, Y; Teng, T; Wang, H; Yin, X; Zhang, R; Zhu, Y | 1 |
Fraz, S; Galus, M; Gugilla, A; Jönsson, M; Wilson, JY | 1 |
Amoozgar, H; Mehdizadegan, N; Moghtaderi, M; Najib, KS; Oboodi, R; Pourarian, S; Sabzevari, F | 1 |
2 review(s) available for acetaminophen and dinoprostone
Article | Year |
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Effects of eicosanoids on the water and sodium balance of the neonate.
Topics: Acetaminophen; Adult; Aging; Animals; Animals, Newborn; Dinoprostone; Eicosanoids; Humans; Infant, Newborn; Kidney; Macaca mulatta; Rats; Thromboxane B2; Water-Electrolyte Balance | 1990 |
Possible effects of repeated exposure to ibuprofen and acetaminophen on the intestinal immune response in young infants.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; CD4-Positive T-Lymphocytes; Child; Child, Preschool; Dinoprostone; Humans; Ibuprofen; Immune Tolerance; Infant; Infant, Newborn; Intestinal Mucosa; Models, Animal; Models, Immunological | 2016 |
14 trial(s) available for acetaminophen and dinoprostone
Article | Year |
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Acetaminophen as a pain enhancer during voluntary interruption of pregnancy with mifepristone and sulprostone.
Topics: Abortifacient Agents, Nonsteroidal; Abortion, Induced; Acetaminophen; Dinoprostone; Double-Blind Method; Drug Interactions; Female; Humans; Male; Mifepristone; Pain; Pregnancy | 1990 |
The comparative effects of paracetamol and indomethacin on renal function in healthy female volunteers.
Topics: 6-Ketoprostaglandin F1 alpha; Acetaminophen; Acetylglucosaminidase; Adult; beta 2-Microglobulin; Creatinine; Dinoprostone; Female; Glomerular Filtration Rate; Humans; Indomethacin; Inulin; Kidney; Kidney Function Tests; Osmolar Concentration; p-Aminohippuric Acid; Renal Circulation; Renin; Urodynamics | 1990 |
Effects of acetylsalicylic acid and paracetamol alone and in combination on prostanoid synthesis in man.
Topics: Acetaminophen; Adult; Aspirin; Creatinine; Dinoprostone; Drug Interactions; Gas Chromatography-Mass Spectrometry; Humans; Kidney; Male; Prostaglandins; Prostanoic Acids; Random Allocation | 1990 |
The interaction of paracetamol with frusemide.
Topics: 6-Ketoprostaglandin F1 alpha; Acetaminophen; Adult; Dinoprostone; Diuresis; Drug Interactions; Female; Furosemide; Humans; Middle Aged; Natriuresis; Radioimmunoassay; Renin | 1994 |
Effects of acetaminophen and ibuprofen on renal function in the stressed kidney.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Dehydration; Diet, Sodium-Restricted; Dinoprostone; Exercise Test; Female; Heat Stress Disorders; Humans; Ibuprofen; Kidney; Kidney Function Tests; Male; Potassium; Renin; Single-Blind Method; Sodium; Stress, Physiological | 1999 |
Antihypertensive effect of the combination of fosinopril and HCTZ is resistant to interference by nonsteroidal antiinflammatory drugs.
Topics: Acetaminophen; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Blood Pressure; Butanones; Creatinine; Dinoprostone; Diuretics; Drug Interactions; Drug Therapy, Combination; Female; Fosinopril; Glomerular Filtration Rate; Humans; Hydrochlorothiazide; Hypertension; Ibuprofen; Middle Aged; Nabumetone; Renal Plasma Flow; Sodium; Sodium Chloride Symporter Inhibitors; Sulindac; Thromboxane B2 | 1999 |
Skeletal muscle PGF(2)(alpha) and PGE(2) in response to eccentric resistance exercise: influence of ibuprofen acetaminophen.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Dinoprost; Dinoprostone; Double-Blind Method; Exercise; Humans; Ibuprofen; Male; Muscle, Skeletal | 2001 |
Cyclooxygenase inhibitors and the antiplatelet effects of aspirin.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Drug Interactions; Drug Therapy, Combination; Humans; Ibuprofen; Isoenzymes; Lactones; Membrane Proteins; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Sulfones; Thromboxane B2 | 2001 |
Acetaminophen selectively suppresses peripheral prostaglandin E2 release and increases COX-2 gene expression in a clinical model of acute inflammation.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Cyclooxygenase 2; Dinoprostone; Female; Gene Expression; Humans; Inflammation; Male; Membrane Proteins; Pain, Postoperative; Tooth Extraction | 2007 |
The differential effects of bupivacaine and lidocaine on prostaglandin E2 release, cyclooxygenase gene expression and pain in a clinical pain model.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Codeine; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Double-Blind Method; Enzyme Induction; Female; Humans; Lactones; Lidocaine; Male; Molar, Third; Mouth Mucosa; Oral Surgical Procedures; Pain Measurement; Pain, Postoperative; Sulfones; Time Factors; Tooth, Impacted | 2008 |
Short-term acetaminophen consumption enhances the exercise-induced increase in Achilles peritendinous IL-6 in humans.
Topics: Acetaminophen; Achilles Tendon; Administration, Oral; Adult; Cyclooxygenase 2 Inhibitors; Dinoprostone; Double-Blind Method; Exercise; Female; Humans; Interleukin-6; Male; Microdialysis; Young Adult | 2013 |
Effects of various analgesics on the level of prostaglandin E2 during orthodontic tooth movement.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Child; Dinoprostone; Double-Blind Method; Female; Gingival Crevicular Fluid; Humans; Ibuprofen; Male; Pain; Pain Measurement; Prospective Studies; Tooth Movement Techniques; Young Adult | 2014 |
Comparison of the effects of ibuprofen and acetaminophen on PGE2 levels in the GCF during orthodontic tooth movement: a human study.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cuspid; Dental Alloys; Dinoprostone; Follow-Up Studies; Gingival Crevicular Fluid; Humans; Ibuprofen; Nickel; Orthodontic Anchorage Procedures; Orthodontic Wires; Stress, Mechanical; Titanium; Tooth Movement Techniques | 2013 |
Positive tendency toward synchronous use of acetaminophen and ibuprofen in treating patients with patent ductus arteriosus.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Dinoprostone; Drug Therapy, Combination; Ductus Arteriosus, Patent; Echocardiography; Female; Gestational Age; Humans; Ibuprofen; Infant; Infant, Newborn; Infant, Premature; Male; Safety; Treatment Outcome | 2020 |
65 other study(ies) available for acetaminophen and dinoprostone
Article | Year |
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Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
The antinociceptive activity of paracetamol in zymosan-induced peritonitis in mice: the role of prostacyclin and reactive oxygen species.
Topics: 6-Ketoprostaglandin F1 alpha; Acetaminophen; Analgesics; Animals; Dinoprostone; Epoprostenol; Free Radicals; Iloprost; Lipid Peroxides; Luminescent Measurements; Macrophages; Male; Mice; Peritonitis; Platelet Aggregation Inhibitors; Superoxides; Zymosan | 1990 |
Acute effects of paracetamol on prostaglandin synthesis and renal function in normal man and in patients with renal failure.
Topics: Acetaminophen; Acute Kidney Injury; Adult; Age Factors; Aged; Creatinine; Dinoprostone; Female; Glomerular Filtration Rate; Homeostasis; Humans; Kidney Tubules; Male; Middle Aged; Reference Values; Sodium; Thromboxane B2 | 1990 |
Estimation of the in vivo effect of cyclooxygenase inhibitors on prostaglandin E2 levels in mouse brain.
Topics: Abdominal Muscles; Acetaminophen; Acetylcholine; Animals; Aspirin; Brain Chemistry; Brain Stem; Cerebral Cortex; Chromatography, Thin Layer; Cyclooxygenase Inhibitors; Dinoprostone; Hypothalamus; Ibuprofen; Indomethacin; Male; Mice; Microsomes; Nociceptors; Pain Measurement; Prostaglandin-Endoperoxide Synthases | 1990 |
Development of the receptors to prostaglandin E2 in the rat kidney and neonatal renal functions.
Topics: Acetaminophen; Aging; Animals; Dinoprostone; Female; In Vitro Techniques; Indomethacin; Kidney; p-Aminohippuric Acid; Rats; Rats, Inbred Strains; Receptors, Prostaglandin; Receptors, Prostaglandin E; Water Deprivation; Water-Electrolyte Balance | 1989 |
Effect of synthesis inhibitors of thromboxane A2 and prostaglandin E2 on the regulation of sodium and water.
Topics: Acetaminophen; Age Factors; Animals; Body Water; Dinoprostone; Female; Imidazoles; Rana pipiens; Rats; Rats, Inbred Strains; Sodium; Thromboxane A2; Vasopressins | 1989 |
Mode of analgesic action of dipyrone: direct antagonism of inflammatory hyperalgesia.
Topics: Acetaminophen; Aminopyrine; Analgesics; Animals; Aspirin; Bucladesine; Carrageenan; Dinoprostone; Dipyrone; Edema; Hyperalgesia; Hyperesthesia; Indomethacin; Isoproterenol; Male; Prostaglandins E; Rats; Rats, Inbred Strains | 1985 |
Protection by mild irritants against indomethacin-induced gastric mucosal damage in the rat: role of prostaglandin synthesis.
Topics: 6-Ketoprostaglandin F1 alpha; Acetaminophen; Animals; Dinoprostone; Ethanol; Gastric Acid; Gastric Mucosa; Indomethacin; Irritants; Male; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Prostaglandins E; Rats; Salicylates; Salicylic Acid; Saline Solution, Hypertonic; Sodium Hydroxide; Stomach Ulcer | 1986 |
Acetaminophen directly protects human gastric epithelial cell monolayers against damage induced by sodium taurocholate.
Topics: Acetaminophen; Cells, Cultured; Dinoprostone; Epithelial Cells; Epithelium; Gastric Mucosa; Histocytochemistry; Humans; In Vitro Techniques; Indomethacin; Prostaglandins E; Stomach Diseases; Taurocholic Acid | 1988 |
Cytoprotective effect of acetaminophen against taurocholate-induced damage to rat gastric monolayer cultures.
Topics: 6-Ketoprostaglandin F1 alpha; Acetaminophen; Animals; Cells, Cultured; Dinoprostone; Dose-Response Relationship, Drug; Gastric Mucosa; Indomethacin; Microscopy, Phase-Contrast; Prostaglandins E; Rats; Rats, Inbred Strains; Taurocholic Acid | 1988 |
Analysis of the antipyretic action of alpha-melanocyte-stimulating hormone in rabbits.
Topics: Acetaminophen; Animals; Arachidonic Acids; Body Temperature; Cerebral Ventricles; Cold Temperature; Dinoprostone; Interleukin-1; Male; Melanocyte-Stimulating Hormones; Prostaglandins E; Proteins; Pyrogens; Rabbits; Time Factors | 1985 |
Comparison of the effects of different anti-inflammatory drugs on synovial fluid prostanoid concentrations in patients with rheumatoid arthritis.
Topics: 6-Ketoprostaglandin F1 alpha; Acetaminophen; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Carbazoles; Diclofenac; Dinoprostone; Guanidines; Humans; Indomethacin; Naproxen; ortho-Aminobenzoates; Prednisolone; Prostaglandins; Prostaglandins E; Quinazolines; Synovial Fluid; Thromboxane B2 | 1985 |
Modulation by drugs of leukotriene and prostaglandin production from mouse peritoneal macrophages.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetaminophen; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calcimycin; Dinoprostone; Dipyrone; Indomethacin; Macrophages; Male; Mice; Propionates; Prostaglandins E; Pyrazoles; Pyrazolones; SRS-A | 1985 |
Clinical assessment of the renal toxicity of antirheumatic drugs.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Dinoprostone; Humans; Ibuprofen; Kidney Diseases; Kidney Function Tests; Phenacetin; Prostaglandins; Prostaglandins E | 1984 |
Comparative study on the effects of acetylsalicylic acid, indomethacin and paracetamol on metabolites of arachidonic acid in plasma, serum and urine in man.
Topics: Acetaminophen; Arachidonic Acid; Arachidonic Acids; Aspirin; Dinoprostone; Humans; Indomethacin; Prostaglandins E; Thromboxane B2 | 1983 |
Indomethacin and paracetamol: interaction with prostaglandin synthesis in the rat stomach.
Topics: Acetaminophen; Animals; Dinoprostone; Epoprostenol; Gastric Mucosa; Indomethacin; Male; Prostaglandins; Prostaglandins E; Rats; Rats, Inbred Strains; Time Factors | 1982 |
Ketoconazole inhibits acetaminophen-induced hepatotoxicity in mice.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Dinoprostone; Female; Ketoconazole; Leukotriene C4; Liver; Male; Mice; Mice, Inbred CBA; Thromboxane A2 | 1995 |
The mode of action of aspirin-like drugs: effect on inducible nitric oxide synthase.
Topics: Acetaminophen; Amino Acid Oxidoreductases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Line; Cell-Free System; Dinoprostone; Dose-Response Relationship, Drug; Electron Transport Complex IV; Enzyme Induction; Gene Expression; Hydrocortisone; Indomethacin; Kinetics; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide Synthase; Sodium Salicylate | 1995 |
Effect of acetaminophen on stress-induced gastric mucosal lesions in rats.
Topics: Acetaminophen; Animals; Dinoprostone; Drug Combinations; Gastric Mucosa; Glutathione; Indomethacin; Injections, Intraperitoneal; Lipid Peroxides; Liver; Male; Rats; Rats, Wistar; Stomach Ulcer; Stress, Physiological | 1994 |
Tubular effects of acetaminophen in the isolated perfused rat kidney.
Topics: Acetaminophen; Analysis of Variance; Animals; Dinoprostone; Drug Interactions; In Vitro Techniques; Kidney Tubules; Male; Perfusion; Rats; Rats, Wistar; Verapamil | 1995 |
The effect of interleukin 1 alpha on acetaminophen-induced hepatotoxicity.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Dinoprostone; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Hepatitis, Animal; Indomethacin; Interleukin-1; Leukotriene C4; Liver; Male; Mice; Mice, Inbred CBA | 1993 |
Effect of acetylsalicylic acid, paracetamol, caffeine and a combination of these substances on the renal prostaglandin E2, 6-keto-prostaglandin F1 alpha, water, creatinine and electrolyte excretion of the rat.
Topics: 6-Ketoprostaglandin F1 alpha; Acetaminophen; Analgesics, Non-Narcotic; Animals; Aspirin; Body Water; Caffeine; Central Nervous System Stimulants; Creatinine; Dinoprostone; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Electrolytes; Female; Kidney; Rats; Rats, Inbred Strains | 1996 |
The effect of acetaminophen, ibuprofen, and misoprostol on prostaglandin E2 synthesis and the degree and rate of orthodontic tooth movement.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Gingival Crevicular Fluid; Guinea Pigs; Ibuprofen; Incisor; Male; Maxilla; Misoprostol; Orthodontic Appliances; Oxytocics; Pain; Periodontal Ligament; Random Allocation; Tooth Movement Techniques | 1996 |
Protective effect of acetaminophen against acute gastric mucosal lesions induced by ischemia-reperfusion in the rat.
Topics: Acetaminophen; Acute Disease; Animals; Antioxidants; Dinoprostone; Free Radicals; Gastric Mucosa; Lipid Peroxides; Male; Rats; Rats, Wistar; Reperfusion Injury | 1997 |
Inflammatory molecule release by beta-amyloid-treated T98G astrocytoma cells: role of prostaglandins and modulation by paracetamol.
Topics: Acetaminophen; Amyloid beta-Peptides; Analgesics, Non-Narcotic; Astrocytoma; Culture Media, Conditioned; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Humans; Inflammation Mediators; Interleukin-1; Interleukin-6; Isoenzymes; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Prostaglandins; RNA, Messenger; Tumor Cells, Cultured | 1998 |
Effects of acetaminophen and ibuprofen on renal function in anesthetized normal and sodium-depleted dogs.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Diet, Sodium-Restricted; Dinoprostone; Dogs; Hemodynamics; Ibuprofen; Kidney; Kidney Function Tests; Renal Circulation; Sodium | 1999 |
Acetaminophen inhibits spinal prostaglandin E2 release after peripheral noxious stimulation.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Dinoprostone; Male; Pain; Rats; Rats, Sprague-Dawley; Spinal Cord | 1999 |
Comparison of acetaminophen, ibuprofen, and nabumetone therapy in rats with pulpal pathosis.
Topics: Acetaminophen; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Dental Pulp Exposure; Dinoprostone; Ibuprofen; Leukotriene Antagonists; Leukotriene B4; Male; Nabumetone; Prostaglandin Antagonists; Rats; Rats, Wistar | 1999 |
Effects of caffeine and paracetamol alone or in combination with acetylsalicylic acid on prostaglandin E(2) synthesis in rat microglial cells.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Aspirin; Caffeine; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Isoenzymes; Lipopolysaccharides; Microglia; Phosphodiesterase Inhibitors; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar | 2000 |
A protective role for cyclooxygenase-2 in drug-induced liver injury in mice.
Topics: Acetaminophen; Animals; Celecoxib; Chemical and Drug Induced Liver Injury; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; DNA Primers; Gene Expression Profiling; Immunoblotting; Isoenzymes; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Survival Rate | 2001 |
Determinants of the cellular specificity of acetaminophen as an inhibitor of prostaglandin H(2) synthases.
Topics: 6-Ketoprostaglandin F1 alpha; Acetaminophen; Analgesics, Non-Narcotic; Arachidonic Acid; Blood Platelets; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dinoprostone; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Hydrogen Peroxide; Interleukin-1; Intramolecular Oxidoreductases; Isoenzymes; Lipid Peroxidation; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Prostaglandins G; Substrate Specificity; Umbilical Veins | 2002 |
Effects of paracetamol and propacetamol on gastric mucosal damage and gastric lipid peroxidation caused by acetylsalicylic acid (ASA) in rats.
Topics: Acetaminophen; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dinoprostone; Dose-Response Relationship, Drug; Gastric Mucosa; Glutathione; Lipid Peroxidation; Male; Malondialdehyde; Peptic Ulcer; Rats; Rats, Wistar; Uric Acid | 2002 |
Paracetamol effectively reduces prostaglandin E2 synthesis in brain macrophages by inhibiting enzymatic activity of cyclooxygenase but not phospholipase and prostaglandin E synthase.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Blotting, Western; Cells, Cultured; Cerebral Cortex; Dinoprostone; Intramolecular Oxidoreductases; Microglia; Nitric Oxide; Phospholipases; Prostaglandin-E Synthases; Prostaglandin-Endoperoxide Synthases; Rats; Tumor Necrosis Factor-alpha | 2003 |
Renal PGE2 production in the human and rat following phenacetin, acetaminophen and p-aminophenol.
Topics: Acetaminophen; Aminophenols; Animals; Dinoprostone; Humans; Immunoassay; Kidney Medulla; Male; Microsomes; Phenacetin; Rats; Rats, Sprague-Dawley | 2002 |
Acetaminophen-induced hypothermia in mice is mediated by a prostaglandin endoperoxide synthase 1 gene-derived protein.
Topics: Acetaminophen; Aminopyrine; Animals; Antipyrine; Brain; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Hypothermia; Isoenzymes; Kinetics; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Polymerase Chain Reaction; Prostaglandin-Endoperoxide Synthases; RNA, Messenger | 2004 |
Acetaminophen-sensitive prostaglandin production in rat cerebral endothelial cells.
Topics: 6-Ketoprostaglandin F1 alpha; Acetaminophen; Analgesics, Non-Narcotic; Animals; Blotting, Western; Capillaries; Cells, Cultured; Cerebrovascular Circulation; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Endothelial Cells; Lipopolysaccharides; Male; Membrane Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides | 2005 |
Conversion of acetaminophen to the bioactive N-acylphenolamine AM404 via fatty acid amide hydrolase-dependent arachidonic acid conjugation in the nervous system.
Topics: Acetaminophen; Amidohydrolases; Aminophenols; Animals; Arachidonic Acid; Arachidonic Acids; Brain; Cell Line; Central Nervous System; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Female; Ganglia, Spinal; Macrophages; Membrane Proteins; Mice; Mice, Knockout; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar | 2005 |
The involvement of a cyclooxygenase 1 gene-derived protein in the antinociceptive action of paracetamol in mice.
Topics: 6-Ketoprostaglandin F1 alpha; Acetaminophen; Aminopyrine; Analgesics, Non-Narcotic; Animals; Antipyrine; Behavior, Animal; Blotting, Western; Brain; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Dose-Response Relationship, Drug; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Prostaglandin-Endoperoxide Synthases; Spinal Cord | 2006 |
Acetaminophen potentiates staurosporine-induced death in a human neuroblastoma cell line.
Topics: Acetaminophen; Acetylcysteine; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Survival; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochromes c; Dinoprostone; Disulfiram; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Free Radical Scavengers; Glutathione; Humans; Metalloporphyrins; Neuroblastoma; Prostaglandin-Endoperoxide Synthases; Staurosporine; Time Factors | 2007 |
Effect of aspirin, paracetamol and their nitric oxide donating derivatives on exudate cytokine and PGE2 production in zymosan-induced air pouch inflammation in rats.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dinoprostone; Dose-Response Relationship, Drug; Female; Immunoenzyme Techniques; Inflammation; Interleukin-1beta; Neutrophils; Nitrates; Nitric Oxide Donors; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha; Zymosan | 2007 |
Increased tumor necrosis factor-alpha and prostaglandin E2 concentrations in the cerebrospinal fluid of rats with inflammatory hyperalgesia: the effects of analgesic drugs.
Topics: Acetaminophen; Administration, Oral; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Behavior, Animal; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Drug Combinations; Freund's Adjuvant; Hyperalgesia; Inflammation; Male; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Sulfonamides; Touch; Tramadol; Tumor Necrosis Factor-alpha | 2007 |
Preoptic nitric oxide attenuates endotoxic fever in guinea pigs by inhibiting the POA release of norepinephrine.
Topics: Acetaminophen; Adrenergic alpha-Antagonists; Animals; Body Temperature; Catheterization; Cyclooxygenase Inhibitors; Dinoprostone; Fever; Guinea Pigs; Jugular Veins; Lipopolysaccharides; Male; Microdialysis; Norepinephrine; Prazosin; Preoptic Area; Salmonella enteritidis; Yohimbine | 2007 |
Preoptic norepinephrine mediates the febrile response of guinea pigs to lipopolysaccharide.
Topics: Acetaminophen; Adrenergic alpha-Antagonists; Animals; Body Temperature; Catheterization; Cyclooxygenase Inhibitors; Dinoprostone; Fever; Guinea Pigs; Jugular Veins; Lipopolysaccharides; Male; Microdialysis; Norepinephrine; Prazosin; Preoptic Area; Salmonella enteritidis; Yohimbine | 2007 |
Acetaminophen: antipyretic or hypothermic in mice? In either case, PGHS-1b (COX-3) is irrelevant.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Cyclooxygenase 1; Dinoprostone; Handling, Psychological; Hypothermia, Induced; Lipopolysaccharides; Membrane Proteins; Mice; Mice, Knockout; Prostaglandin-Endoperoxide Synthases | 2008 |
Acetaminophen prevents hyperalgesia in central pain cascade.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Animals; Dinoprostone; Hyperalgesia; Injections, Spinal; Male; Neurotransmitter Agents; Pain; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P | 2008 |
Characterization and pharmacological evaluation of febrile response on zymosan-induced arthritis in rats.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Arthritis, Experimental; Body Temperature; Celecoxib; Dexamethasone; Dinoprostone; Dipyrone; Dose-Response Relationship, Drug; Fever; Ibuprofen; Injections, Intra-Articular; Male; Pyrazoles; Rats; Rats, Wistar; Sulfonamides; Zymosan | 2009 |
The role of prostaglandin E2 in acute acetaminophen hepatotoxicity in mice.
Topics: Acetaminophen; Alanine Transaminase; Animals; Cytoprotection; Dinoprostone; Drug Overdose; Drug-Related Side Effects and Adverse Reactions; Female; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Nitric Oxide Synthase Type II | 2010 |
Study of inhibitors of the PGH synthases for which potency is regulated by the redox state of the enzymes.
Topics: Acetaminophen; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Cell Line, Tumor; Cyclooxygenase Inhibitors; Dinoprostone; Gas Chromatography-Mass Spectrometry; Humans; Hydrogen Peroxide; Mice; Oxidation-Reduction; Prostaglandin-Endoperoxide Synthases; Salicylic Acid; Thromboxane B2 | 2010 |
PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Animals, Genetically Modified; Chemical and Drug Induced Liver Injury; Dinoprostone; Genes, Reporter; Glutathione; Liver; Liver Failure, Acute; Proteome; Signal Transduction; Zebrafish | 2010 |
Secretory phospholipase A₂-mediated progression of hepatotoxicity initiated by acetaminophen is exacerbated in the absence of hepatic COX-2.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Cyclooxygenase 2; Dinoprostone; Disease Progression; Liver Regeneration; Male; Mice; Mice, Knockout; Phospholipases A2, Secretory; Survival; Time Factors; Tumor Necrosis Factor-alpha | 2011 |
Paracetamol reduces influenza-induced immunopathology in a mouse model of infection without compromising virus clearance or the generation of protective immunity.
Topics: Acetaminophen; Adaptive Immunity; Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Dinoprostone; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Immunity, Innate; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Liver; Lung; Mice; Mice, Inbred C57BL; Orthomyxoviridae Infections; Pyrazoles; Respiratory Tract Infections; Sulfonamides; Viral Load; Virus Shedding | 2011 |
A matched case control study with propensity score balancing examining the protective effect of paracetamol against parentally reported apnoea in infants.
Topics: Acetaminophen; Apnea; Case-Control Studies; Dinoprostone; Dose-Response Relationship, Drug; Drug Administration Schedule; Emergency Service, Hospital; Female; Follow-Up Studies; Humans; Ibuprofen; Incidence; Infant; Infant, Newborn; Logistic Models; Male; Parents; Predictive Value of Tests; Propensity Score; Reference Values; Risk Assessment; Severity of Illness Index; Treatment Outcome | 2012 |
Effect of trifluoperazine on toxicity, HIF-1α induction and hepatocyte regeneration in acetaminophen toxicity in mice.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Cytokines; Dinoprostone; Hepatocytes; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Indicators and Reagents; Intercellular Signaling Peptides and Proteins; Liver Regeneration; Male; Mice; Mitochondria, Liver; Permeability; Proliferating Cell Nuclear Antigen; Prostaglandin-Endoperoxide Synthases; Receptors, Phospholipase A2; Signal Transduction; Trifluoperazine; Tumor Necrosis Factor-alpha | 2012 |
Acetaminophen reduces lipopolysaccharide-induced fever by inhibiting cyclooxygenase-2.
Topics: Acetaminophen; Animals; Antipyretics; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Fever; Gene Expression Regulation, Enzymologic; Heterozygote; Hypothalamus; Injections, Intraventricular; Intramolecular Oxidoreductases; Lipopolysaccharides; Mice; Mice, Inbred DBA; Mice, Knockout; Nerve Tissue Proteins; Neurons; Prosencephalon; Prostaglandin-E Synthases | 2013 |
Arsenic reduces the antipyretic activity of paracetamol in rats: modulation of brain COX-2 activity and CB₁ receptor expression.
Topics: Acetaminophen; Animals; Antipyretics; Arsenic; Brain; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Drug Interactions; Fever; Interleukin-1beta; Lipopolysaccharides; Male; Membrane Proteins; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; RNA, Messenger; Tumor Necrosis Factor-alpha; Water Pollutants, Chemical | 2014 |
Amelioration of paracetamol-induced hepatotoxicity in rat by the administration of methanol extract of Muntingia calabura L. leaves.
Topics: Acetaminophen; Active Transport, Cell Nucleus; AMP-Activated Protein Kinases; Animals; Cell Nucleus; Dinoprostone; Down-Regulation; Humans; Immunohistochemistry; Inflammation; Interleukin-6; Lipopolysaccharides; Liver; Liver Failure; Methanol; Mice; Microglia; NF-kappa B; Nitric Oxide; Plant Extracts; Plant Leaves; Rats; Sasa; Tumor Necrosis Factor-alpha | 2014 |
[Prostaglandins and the immune response at the intestinal submucosal level. A potential site for interference with the repeated use of paracetamol and ibuprofen at a young age?].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Child, Preschool; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Ibuprofen; Immunity, Cellular; Intestinal Mucosa | 2015 |
PGE2 induced in and released by dying cells functions as an inhibitory DAMP.
Topics: Acetaminophen; Alarmins; Animals; Cell Death; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Cyclooxygenase 2; Dinoprostone; HeLa Cells; Humans; Inflammation; Lipopolysaccharides; Mice; Mice, Inbred C57BL | 2016 |
Cyclooxygenase-1 and -2 Play Contrasting Roles in
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; CD8-Positive T-Lymphocytes; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Female; Immunity; Immunity, Innate; Listeria monocytogenes; Listeriosis; Male; Membrane Proteins; Mice; Mice, Inbred C57BL | 2018 |
The antipyretic effect of paracetamol occurs independent of transient receptor potential ankyrin 1-mediated hypothermia and is associated with prostaglandin inhibition in the brain.
Topics: Acetaminophen; Animals; Antipyretics; Brain; Dinoprostone; Hypothermia; Mice; Mice, Knockout; TRPA1 Cation Channel | 2018 |
Prostaglandin E2-Mediated Impairment of Innate Immune Response to A(H1N1)pdm09 Infection in Diet-Induced Obese Mice Could Be Restored by Paracetamol.
Topics: Acetaminophen; Animals; Cytokines; Dinoprostone; Female; Immunity, Innate; Immunologic Factors; Influenza A Virus, H1N1 Subtype; Lung; Mice, Inbred C57BL; Mice, Obese; Orthomyxoviridae Infections; Treatment Outcome | 2019 |
Microsomal prostaglandin E synthase 2 deficiency is resistant to acetaminophen-induced liver injury.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Cysteine; Dinoprostone; Glutathione; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Mice, Knockout; Prostaglandin-E Synthases | 2019 |
Prostaglandins prevent acetaminophen induced embryo toxicity in zebrafish (Danio rerio).
Topics: Acetaminophen; Animals; Dinoprostone; Dose-Response Relationship, Drug; Embryo, Nonmammalian; Female; Male; Prostaglandin-Endoperoxide Synthases; Zebrafish | 2020 |