acetaminophen and dimethylnitrosamine

acetaminophen has been researched along with dimethylnitrosamine in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19906 (40.00)18.7374
1990's3 (20.00)18.2507
2000's3 (20.00)29.6817
2010's3 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Mitchell, JR; Potter, WZ; Sasame, HA; Thorgeirsson, SS1
Dybing, E1
Connor, TH; Forti, GC; Legator, MS; Sitra, P1
Arndt, K; Haschek, WM; Jeffery, EH1
Landon, EJ; Naukam, RJ; Rama Sastry, BV1
Hughes, H; Mitchell, JR; Smith, CV1
Gichner, T; Plewa, MJ; Velemínský, J; Wagner, ED1
Alexander, A; Berthou, F; Mapoles, J; Ménez, JF; Simon, F1
Kaneko, T; Sato, A; Wang, PY; Wang, Y1
Bagchi, D; Bagchi, M; Preuss, HG; Ray, SD; Stohs, SJ1
Bonk, I; Bryant, S; Klatt, M; Köpke, A; Nebrich, G; Taufmann, M; Thome-Kromer, B; Wacker, U1
Kato, H; Katoh, M; Minami, K; Nakajima, M; Narahara, M; Saito, T; Sugiyama, H; Tomita, H; Yokoi, T1
Li, W; Pu, XP; Sun, H; Sun, Y; Wang, YH; Yang, YF; Zhao, X; Zheng, XY1

Other Studies

15 other study(ies) available for acetaminophen and dimethylnitrosamine

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Biochemical changes after hepatic injury by allyl alcohol and N-hydroxy-2-acetylaminofluorene.
    Chemico-biological interactions, 1976, Oct-02, Volume: 15, Issue:2

    Topics: Acetaminophen; Allyl Compounds; Aniline Hydroxylase; Animals; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Cytochromes; Cytosol; Dimethylnitrosamine; Ethylmorphine-N-Demethylase; Fluorenes; Furosemide; Glucose-6-Phosphatase; Hydroxyacetylaminofluorene; Liver; Liver Regeneration; Male; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Nitrogenase; Proteins; Rats

1976
Methyldopa binding to cells in culture.
    Acta pharmacologica et toxicologica, 1977, Volume: 40, Issue:1

    Topics: Acetaminophen; Allopurinol; Animals; Ascorbic Acid; Carcinoma, Hepatocellular; Cells, Cultured; Deferoxamine; Dimethylnitrosamine; Edetic Acid; Furosemide; Glutathione; Liver Neoplasms; Maleates; Methyldopa; Neoplasms, Experimental; Protein Binding; Rats; Superoxide Dismutase; Time Factors; Xanthines

1977
Bile as a source of mutagenic metabolites produced in vivo and detected by Salmonella typhimurium.
    Environmental mutagenesis, 1979, Volume: 1, Issue:3

    Topics: Acetaminophen; Animals; Bile; Biotransformation; Cyclophosphamide; Diethylstilbestrol; Dimethylnitrosamine; Ethylene Dichlorides; Hycanthone; Isoniazid; Male; Methyl Methanesulfonate; Methylcholanthrene; Mutagens; Rats; Salmonella typhimurium; Serum Albumin, Bovine

1979
Mechanism of inhibition of hepatic bioactivation of paracetamol by dimethyl sulfoxide.
    Drug metabolism and drug interactions, 1988, Volume: 6, Issue:3-4

    Topics: Acetaminophen; Animals; Bile; Biotransformation; Chemical and Drug Induced Liver Injury; Dimethyl Sulfoxide; Dimethylnitrosamine; Female; Glucuronates; Glutathione; In Vitro Techniques; Kinetics; Lipid Peroxidation; Liver; Mice; Rats; Rats, Inbred Strains; Sulfates

1988
Effects of calcium channel blocking agents on calcium and centrilobular necrosis in the liver of rats treated with hepatotoxic agents.
    Biochemical pharmacology, 1986, Feb-15, Volume: 35, Issue:4

    Topics: Acetaminophen; Animals; Calcium; Calcium Channel Blockers; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chloroform; Dimethylnitrosamine; Liver; Male; Microsomes, Liver; Necrosis; Rats; Rats, Inbred Strains; Thioacetamide

1986
Free radicals in vivo. Covalent binding to lipids.
    Molecular pharmacology, 1984, Volume: 26, Issue:1

    Topics: Acetaminophen; Animals; Bromobenzenes; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry; Dimethylnitrosamine; Free Radicals; Furans; Furosemide; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred ICR; Rats; Rats, Inbred Strains

1984
Inhibitory effects of acetaminophen, 7,8-benzoflavone and methimazole towards N-nitrosodimethylamine mutagenesis in Arabidopsis thaliana.
    Mutation research, 1993, Volume: 300, Issue:1

    Topics: Acetaminophen; Antimutagenic Agents; Arabidopsis; Benzoflavones; Dimethylnitrosamine; Dose-Response Relationship, Drug; Methimazole; Mutagenesis; Mutagens; Seeds; Spectrophotometry

1993
Mammalian PC-12 cell genetically engineered for human cytochrome P450 2E1 expression.
    European journal of biochemistry, 1993, Jun-15, Volume: 214, Issue:3

    Topics: 1-Butanol; Acetaminophen; Animals; Butanols; Chlorzoxazone; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Ditiocarb; Genetic Engineering; Humans; Hydroxylation; Microsomes; Oxidoreductases, N-Demethylating; Oxygenases; PC12 Cells; Transfection

1993
Acarbose alone or in combination with ethanol potentiates the hepatotoxicity of carbon tetrachloride and acetaminophen in rats.
    Hepatology (Baltimore, Md.), 1999, Volume: 29, Issue:1

    Topics: Acarbose; Acetaminophen; Alkylating Agents; Analgesics, Non-Narcotic; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Dimethylnitrosamine; Drug Synergism; Enzyme Induction; Enzyme Inhibitors; Ethanol; Immunochemistry; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Trisaccharides

1999
Mechanistic pathways of antioxidant cytoprotection by a novel IH636 grape seed proanthocyanidin extract.
    Indian journal of experimental biology, 2002, Volume: 40, Issue:6

    Topics: Acetaminophen; Administration, Oral; Alanine Transaminase; Amiodarone; Analgesics, Non-Narcotic; Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Blood Urea Nitrogen; Cell Cycle; Creatine Kinase; Dimethylnitrosamine; DNA Damage; Doxorubicin; Drug-Related Side Effects and Adverse Reactions; Free Radical Scavengers; Grape Seed Extract; Heart Diseases; Humans; In Vitro Techniques; Injections, Intraperitoneal; Keratinocytes; Kidney Diseases; Lipid Peroxidation; Lung Diseases; Mice; Mice, Inbred ICR; Necrosis; Oxidation-Reduction; Plant Extracts; Proanthocyanidins; Spleen; Tobacco, Smokeless; Vasodilator Agents

2002
Toward the identification of liver toxicity markers: a proteome study in human cell culture and rats.
    Proteomics, 2003, Volume: 3, Issue:10

    Topics: 1-Naphthylisothiocyanate; Acetaminophen; Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Animals; Biomarkers; Carbamoyl-Phosphate Synthase (Ammonia); Catalase; Cell Line, Tumor; Cisplatin; Databases, Protein; Dimethylnitrosamine; Electrophoresis, Gel, Two-Dimensional; Hexokinase; Humans; Indomethacin; Isoelectric Point; Liver; Male; Molecular Weight; Protein Isoforms; Proteins; Proteome; Proteomics; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetracycline

2003
Relationship between hepatic gene expression profiles and hepatotoxicity in five typical hepatotoxicant-administered rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 2005, Volume: 87, Issue:1

    Topics: Acetaminophen; Alkaline Phosphatase; Animals; Bromobenzenes; Carbon Tetrachloride; Dimethylnitrosamine; Gene Expression Profiling; L-Lactate Dehydrogenase; Liver; Male; Rats; Rats, Sprague-Dawley; Thioacetamide

2005
Two xanthones from Swertia punicea with hepatoprotective activities in vitro and in vivo.
    Journal of ethnopharmacology, 2014, May-14, Volume: 153, Issue:3

    Topics: Acetaminophen; Animals; Aspartate Aminotransferases; Bilirubin; Carbon Tetrachloride; Cell Survival; Dimethylnitrosamine; Glutathione; Hep G2 Cells; Humans; L-Lactate Dehydrogenase; Liver; Liver Cirrhosis; Male; Malondialdehyde; Protective Agents; Rats, Wistar; Reactive Oxygen Species; Serum Albumin; Superoxide Dismutase; Swertia; Xanthones

2014