acetaminophen has been researched along with dimethyl sulfoxide in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (33.33) | 18.7374 |
| 1990's | 7 (21.21) | 18.2507 |
| 2000's | 9 (27.27) | 29.6817 |
| 2010's | 6 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Siegers, CP | 1 |
| Hart, FE; Willson, RA | 2 |
| Corbett, BR; Corbett, MD; Hannothiaux, MH; Quintana, SJ | 1 |
| Kasper, P; Madle, S; Müller, L | 1 |
| Arndt, K; Haschek, WM; Jeffery, EH | 3 |
| Georgiou, CA; Koupparis, MA | 1 |
| Støttum, A; Wiger, R | 1 |
| Combs, AB; Kehrer, JP; Park, Y; Smith, RD | 1 |
| Haschek, WM; Jeffery, EH | 1 |
| Hayes, MA; Pickering, DB | 1 |
| Siegers, CP; Younes, M | 1 |
| El-Hage, AN; Ferrans, VJ; Herman, EH | 1 |
| Kourounakis, AP; Kourounakis, PN; Rekka, EA | 1 |
| Fautrel, A; Guillouzo, A; Guyomard, C; Joly, B | 1 |
| Akşahin, I; Ozden, T; Senyuva, H | 1 |
| Barnes, MN; Grizzle, WE; Oelschlager, DK; Partridge, EE; Rodríguez-Burford, C; Talley, LI | 1 |
| Ali, S; Pawa, S | 1 |
| Hartung, T; Jennings, P; Koppelstaetter, C; Morin, JP; Pfaller, W; Ryan, MP | 1 |
| Altinoz, MA; Bilir, A; Guneri, AD | 1 |
| Aninat, C; Glaise, D; Guguen-Guillouzo, C; Guillouzo, A; Langouët, S; Le Charpentier, T; Morel, F; Piton, A | 1 |
| Bajt, ML; Cover, C; Jaeschke, H | 1 |
| Chung, JH; Kim, SJ; Kim, YC; Lee, BH; Yoon, MY | 1 |
| Carpenter, LD; Graf, ML; Masson, MJ; Pohl, LR | 1 |
| Jaeschke, H | 1 |
| Farhood, A; Jaeschke, H; Williams, CD | 1 |
| Bhyrapuneni, G; Kandikere, V; Manoharan, A; Nirogi, R; Palacharla, Rc; Ponnamaneni, RK | 1 |
| Du, K; Farhood, A; Jaeschke, H; McGill, MR; Vinken, M; Williams, CD; Xie, Y | 1 |
| Bryant, SC; Gastineau, DA; Greiner, CW; Hogan, WJ; Jacob, EK; Lingineni, RK; Mohr, A; Mulay, SB; Padley, D | 1 |
| Al-Rejaie, SS; Algfeley, SG; Nagi, MN | 1 |
1 review(s) available for acetaminophen and dimethyl sulfoxide
| Article | Year |
|---|---|
Mechanism of dimethylsulfoxide protection against acetaminophen hepatotoxicity.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Dimethyl Sulfoxide; Humans | 1989 |
32 other study(ies) available for acetaminophen and dimethyl sulfoxide
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Antidotal effects of dimethyl sulphoxide against paracetamol-, bromobenzene-, and thioacetamide-induced hepatotoxicity.
Topics: Acetamides; Acetaminophen; Animals; Antidotes; Bromobenzenes; Dimethyl Sulfoxide; Liver; Male; Mice; Thioacetamide | 1978 |
Effect of experimental hepatic injury on in vitro drug-metabolizing enzyme activities in the rat.
Topics: Acetaminophen; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Bilirubin; Cytochrome P-450 Enzyme System; Dimethyl Sulfoxide; Glucuronosyltransferase; In Vitro Techniques; Liver; Liver Cirrhosis, Experimental; Male; Microsomes, Liver; Rats | 1977 |
In vitro spectral alteration of hepatic cytochrome P-450 by experimental drug injury.
Topics: Acetaminophen; Animals; Buffers; Chemical and Drug Induced Liver Injury; Cysteamine; Cysteine; Cytochrome P-450 Enzyme System; Dimethyl Sulfoxide; Enzyme Induction; Glutathione; In Vitro Techniques; Liver Diseases; Male; Methionine; Microsomes, Liver; Phenobarbital; Rats; Solvents | 1977 |
The covalent binding of acetaminophen to cellular nucleic acids as the result of the respiratory burst of neutrophils derived from the HL-60 cell line.
Topics: Acetaminophen; Cell Line; Dimethyl Sulfoxide; DNA, Neoplasm; Granulocytes; Humans; Leukemia; Neutrophils; Respiratory Burst; RNA, Neoplasm | 1992 |
Further investigations on the clastogenicity of paracetamol and acetylsalicylic acid in vitro.
Topics: Acetaminophen; Animals; Aspirin; Biotransformation; Cell Line; Cells, Cultured; Chromosome Aberrations; Cyclophosphamide; Dimethyl Sulfoxide; Liver; Metaphase; Microsomes, Liver; Mitomycin; Mitomycins; Mutagenicity Tests; Mutagens; Rats; Rats, Inbred Strains | 1991 |
The role of cytochrome P450IIE1 in bioactivation of acetaminophen in diabetic and acetone-treated mice.
Topics: Acetaminophen; Acetone; Animals; Biotransformation; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Diabetes Mellitus, Experimental; Dimethyl Sulfoxide; Female; Liver; Mice; Microsomes, Liver; Oxidoreductases, N-Demethylating | 1991 |
Automated flow injection spectrophotometric determination of para- and meta-substituted phenols of pharmaceutical interest based on their oxidative condensation with 1-nitroso-2-naphthol.
Topics: Acetaminophen; Chemical Phenomena; Chemistry; Dimethyl Sulfoxide; Isoxsuprine; Kinetics; Nitroso Compounds; Phenols; Spectrophotometry; Tyrosine | 1990 |
In vitro testing for developmental toxicity using the Hydra attenuata assay.
Topics: Acetaminophen; Animals; Dimethyl Sulfoxide; Ethanol; Hexachlorocyclohexane; Hydra; Isoniazid; Regeneration; Teratogens; Toxicology; Valproic Acid | 1985 |
Prevention of acetaminophen-induced hepatotoxicity by dimethyl sulfoxide.
Topics: Acetaminophen; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Carbon Radioisotopes; Cytochrome P-450 Enzyme System; Dimethyl Sulfoxide; Glutathione; Male; Mice; Mice, Inbred BALB C; Microsomes, Liver | 1988 |
Mechanism of inhibition of hepatic bioactivation of paracetamol by dimethyl sulfoxide.
Topics: Acetaminophen; Animals; Bile; Biotransformation; Chemical and Drug Induced Liver Injury; Dimethyl Sulfoxide; Dimethylnitrosamine; Female; Glucuronates; Glutathione; In Vitro Techniques; Kinetics; Lipid Peroxidation; Liver; Mice; Rats; Rats, Inbred Strains; Sulfates | 1988 |
Protection by dimethylsulfoxide against acetaminophen-induced hepatic, but not respiratory toxicity in the mouse.
Topics: Acetaminophen; Animals; Carbon Tetrachloride; Dimethyl Sulfoxide; Female; Free Radicals; Glutathione; Liver; Lung; Mice; Necrosis; Respiratory System | 1988 |
Comparative cytopathology of primary rat hepatocyte cultures exposed to aflatoxin B1, acetaminophen, and other hepatotoxins.
Topics: Acetaminophen; Aflatoxin B1; Aflatoxins; Animals; Cells, Cultured; Dimethyl Sulfoxide; Drug-Related Side Effects and Adverse Reactions; L-Lactate Dehydrogenase; Liver; Male; Rats; Rats, Inbred F344; Trypan Blue | 1985 |
Inhibition of the hepatotoxicity of paracetamol and its irreversible binding to rat liver microsomal protein.
Topics: Acetaminophen; Animals; Catechin; Chemical and Drug Induced Liver Injury; Deanol; Dimethyl Sulfoxide; Ditiocarb; In Vitro Techniques; Microsomes, Liver; Phenobarbital; Protein Binding; Rats; Time Factors | 1980 |
Examination of the protective effect of ICRF-187 and dimethyl sulfoxide against acetaminophen-induced hepatotoxicity in Syrian golden hamsters.
Topics: Acetaminophen; Alanine Transaminase; Animals; Blood Proteins; Chemical and Drug Induced Liver Injury; Cricetinae; Dimethyl Sulfoxide; Liver Diseases; Male; Mesocricetus; Necrosis; Piperazines; Razoxane | 1983 |
Antioxidant activity of guaiazulene and protection against paracetamol hepatotoxicity in rats.
Topics: Acetaminophen; Animals; Antioxidants; Azulenes; Bepridil; Biphenyl Compounds; Cytosol; Dimethyl Sulfoxide; Female; Free Radical Scavengers; Glutathione Reductase; Glutathione Transferase; In Vitro Techniques; Lipid Peroxidation; Liver; Microsomes, Liver; Organ Size; Picrates; Rats; Rats, Inbred F344; Sesquiterpenes; Sesquiterpenes, Guaiane | 1997 |
Long-term maintenance of drug-metabolizing enzyme activities in rat hepatocytes after cryopreservation.
Topics: Acetaminophen; Acetylation; Animals; Cell Survival; Cells, Cultured; Cryopreservation; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Dimethyl Sulfoxide; Epithelial Cells; Glucuronates; Liver; Phenacetin; Rats; Rats, Sprague-Dawley | 1997 |
Quantitative analysis of methocarbamol in solid dosage forms with 1H-NMR spectroscopy.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Dimethyl Sulfoxide; Drug Combinations; Magnetic Resonance Spectroscopy; Maleates; Methocarbamol; Muscle Relaxants, Central; Pharmaceutical Preparations; Reference Standards; Reproducibility of Results; Solvents | 1999 |
The use of dimethylsulfoxide as a vehicle in cell culture experiments using ovarian carcinoma cell lines.
Topics: Acetaminophen; Aspirin; Cell Count; Cell Culture Techniques; Cell Division; Cell Line, Tumor; Culture Media; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Ethanol; Female; Humans; Ovarian Neoplasms; Sensitivity and Specificity | 2003 |
Liver necrosis and fulminant hepatic failure in rats: protection by oxyanionic form of tungsten.
Topics: Acetaminophen; Alkaline Phosphatase; Allopurinol; Animals; Bromobenzenes; Carbon Tetrachloride Poisoning; Chloroform; Dimethyl Sulfoxide; Female; Lethal Dose 50; Liver; Liver Failure; Necrosis; Oxidative Stress; Rats; Rats, Wistar; Thioacetamide; Transaminases; Tungsten Compounds | 2004 |
Assessment of a new cell culture perfusion apparatus for in vitro chronic toxicity testing. Part 2: toxicological evaluation.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animal Testing Alternatives; Animals; Cell Culture Techniques; Coloring Agents; Cyclosporine; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; gamma-Glutamyltransferase; Humans; Immunosuppressive Agents; Inhibitory Concentration 50; Kidney Diseases; L-Lactate Dehydrogenase; LLC-PK1 Cells; Oxazines; Perfusion; Sodium Dodecyl Sulfate; Surface-Active Agents; Swine; Time Factors; Toxicity Tests, Chronic; Xanthenes | 2004 |
Acetaminophen and DMSO modulate growth and gemcitabine cytotoxicity in FM3A breast cancer cells in vitro.
Topics: Acetaminophen; Anti-Inflammatory Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Breast Neoplasms; Cell Division; Cyclooxygenase Inhibitors; Deoxycytidine; Dimethyl Sulfoxide; Gemcitabine; Humans; Ribonucleotide Reductases; S Phase; Time Factors; Tumor Cells, Cultured | 2004 |
Expression of cytochromes P450, conjugating enzymes and nuclear receptors in human hepatoma HepaRG cells.
Topics: Acetaminophen; Aflatoxin B1; Amiodarone; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Chlorpromazine; Cytochrome P-450 Enzyme System; Dimethyl Sulfoxide; Gene Expression; Gene Expression Profiling; Glucuronosyltransferase; Hepatocytes; Humans; Inhibitory Concentration 50; Isoenzymes; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Xenobiotics | 2006 |
Role of caspases in acetaminophen-induced liver injury.
Topics: Acetaminophen; Amino Acid Chloromethyl Ketones; Analgesics, Non-Narcotic; Animals; Caspase Inhibitors; Caspases; Chemical and Drug Induced Liver Injury; Cysteine Proteinase Inhibitors; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Liver Diseases; Male; Mice; Mice, Inbred Strains; Solvents | 2006 |
Effects of dimethylsulfoxide on metabolism and toxicity of acetaminophen in mice.
Topics: Acetaminophen; Animals; Chromatography, High Pressure Liquid; Dimethyl Sulfoxide; Glutathione; Male; Mice; Mice, Inbred ICR; Xenobiotics | 2006 |
Pathogenic role of natural killer T and natural killer cells in acetaminophen-induced liver injury in mice is dependent on the presence of dimethyl sulfoxide.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Apoptosis; Cell Culture Techniques; Chemical and Drug Induced Liver Injury; Dimethyl Sulfoxide; Disease Models, Animal; Female; Granzymes; Interferon-gamma; Killer Cells, Natural; Liver Diseases; Male; Mice; Mice, Inbred C57BL; Reproducibility of Results; T-Lymphocyte Subsets | 2008 |
Innate immunity and acetaminophen-induced liver injury: why so many controversies?
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Apoptosis; Chemical and Drug Induced Liver Injury; Dimethyl Sulfoxide; Female; Humans; Immunity, Innate; Killer Cells, Natural; Kupffer Cells; Liver Diseases; Male; Mice; Oxidative Stress | 2008 |
No evidence for caspase-dependent apoptosis in acetaminophen hepatotoxicity.
Topics: Acetaminophen; Animals; Apoptosis; Caspases; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Dimethyl Sulfoxide; Hepatocytes; Liver; Mice; Mice, Inbred C57BL; Models, Animal; Solvents | 2011 |
Effect of dimethyl sulfoxide on in vitro cytochrome P4501A2 mediated phenacetin O-deethylation in human liver microsomes.
Topics: Acetaminophen; Acetonitriles; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Dimethyl Sulfoxide; Humans; Methanol; Microsomes, Liver; Phenacetin; Solvents | 2011 |
The gap junction inhibitor 2-aminoethoxy-diphenyl-borate protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes and c-jun N-terminal kinase activation.
Topics: Acetaminophen; Animals; Boron Compounds; Chemical and Drug Induced Liver Injury; Connexins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dimethyl Sulfoxide; Gap Junction beta-1 Protein; Gap Junctions; Hepatocytes; JNK Mitogen-Activated Protein Kinases; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Signal Transduction; tert-Butylhydroperoxide | 2013 |
Infusion technique of hematopoietic progenitor cells and related adverse events (CME).
Topics: Acetaminophen; Adolescent; Adult; Aged; Blood Preservation; Child; Child, Preschool; Cryopreservation; Cryoprotective Agents; Dimethyl Sulfoxide; Diphenhydramine; Flushing; Furosemide; Hematologic Neoplasms; Humans; Hydrocortisone; Hypertension; Infant; Infant, Newborn; Infusions, Intravenous; Isotonic Solutions; Middle Aged; Nausea; Neutrophils; Peripheral Blood Stem Cell Transplantation; Premedication; Retrospective Studies; Risk Factors; Syringes; Young Adult | 2014 |
Can acetaminophen/dimethyl sulfoxide formulation prevent accidental and intentional acetaminophen hepatotoxicity?
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Drug Combinations; Drug Compounding; Liver; Liver Function Tests; Mice, Inbred C57BL; Nitrosative Stress; Oxidative Stress | 2019 |