acetaminophen and digoxin

acetaminophen has been researched along with digoxin in 40 studies

Research

Studies (40)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (22.50)	18.7374
1990's	3 (7.50)	18.2507
2000's	13 (32.50)	29.6817
2010's	14 (35.00)	24.3611
2020's	1 (2.50)	2.80

Authors

Authors	Studies
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Avdeef, A; Tam, KY	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Levine, L	1
Currin, MR	1
Lovering, EG; McGilveray, IJ; McMillan, I; Tostowaryk, W	1
Sherman, SE; Watkins, JB	1
Watkins, JB	1
Tenenbein, M	1
Greene, W	1
Rácz, I	1
Wilcke, JR	1
Massing, GK; Mockridge, PB; Wilkerson, RD	1
Chyka, PA; Holley, JE; Mandrell, TD; Sugathan, P	1
Dawson, AH; Whyte, IM	2
DiCicco, RA; Graham, AM; Hursting, MJ; Inglis, AM; Sheth, SB; Tenero, DM	1
Faulkner, MA; Lenz, NJ; Lenz, TL	1
Clifford, TJ; Neto, GM; Plint, A; Randhawa, N; Reid, SM	1
Kaukonen, AM; Laitinen, L; Marvola, M; Takala, E; Vuorela, H; Vuorela, P	1
Arias, A; Blazquez, AG; Carpini, GD; Ghanem, CI; Marin, JJ; Mottino, AD; Novak, A; Rubio, MC; Villanueva, S	1
Carpini, GD; Ghanem, CI; Luquita, MG; Mottino, AD; Novak, A; Rubio, MC; Ruiz, ML	1
Inoue, Y	1
Campion, GH; Cormier, M; Ghannoum, M; Gosselin, S; Hoffman, RS; Lavergne, V; Mowry, JB; Roberts, DM; Su, MK; Wang, JJ	1
Chan, LN; Chen, KF; Lin, YS	1

Reviews

11 review(s) available for acetaminophen and digoxin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Reported ocular side effects of the ten most frequently prescribed drugs. Journal of the American Optometric Association, 1979, Volume: 50, Issue:2 Topics: Acetaminophen; Ampicillin; Brompheniramine; Codeine; Diazepam; Digoxin; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Eye; Eye Diseases; Female; Furosemide; Humans; Hydrochlorothiazide; Methyldopa; Phenylephrine; Phenylpropanolamine; Pregnancy; Propranolol; Tetracyclines; Triamterene	1979
Pharmacology of the neonate. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1979, Jul-21, Volume: 56, Issue:3 Topics: Acetaminophen; Adsorption; Aminoglycosides; Barbiturates; Benzodiazepines; Benzothiadiazines; Biological Availability; Body Composition; Cephalosporins; Digoxin; Diuretics; Female; Humans; Infant, Newborn; Injections, Intravenous; Maternal-Fetal Exchange; Meperidine; Penicillins; Pharmaceutical Preparations; Placenta; Pregnancy; Protein Binding; Salicylates; Sodium Chloride Symporter Inhibitors; Theophylline; Tissue Distribution	1979
Pediatric toxicology: current controversies and recent advances. Current problems in pediatrics, 1986, Volume: 16, Issue:4 Topics: Acetaminophen; Acetylcysteine; Antidotes; Charcoal; Chemical and Drug Induced Liver Injury; Child Abuse; Child, Preschool; Digitoxin; Digoxin; Emetics; Female; Gastric Lavage; Humans; Hydrocarbons; Immunoglobulin Fab Fragments; Infant; Male; Naloxone; Narcotics; Poisoning	1986
Drug interactions involving cimetidine--mechanisms, documentation, implications. Quarterly reviews on drug metabolism and drug interactions, 1984, Volume: 5, Issue:1 Topics: Acetaminophen; Adrenergic beta-Antagonists; Analgesics, Opioid; Animals; Antacids; Anti-Anxiety Agents; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Anticoagulants; Anticonvulsants; Antifungal Agents; Aspirin; Benzodiazepines; Cimetidine; Digoxin; Drug Interactions; Humans; Intestinal Absorption; Iron; Lidocaine; Pancreas; Phenytoin; Prednisolone; Theophylline; Vitamin B 12	1984
Idiosyncracies of drug metabolism in cats. Effects on pharmacotherapeutics in feline practice. The Veterinary clinics of North America. Small animal practice, 1984, Volume: 14, Issue:6 Topics: Acetaminophen; Animals; Aspirin; Benzyl Alcohol; Benzyl Alcohols; Biotransformation; Cats; Digoxin; Glucuronates; Liver; Morphine; Pharmaceutical Preparations; Species Specificity; Veterinary Medicine	1984
Therapeutic drug monitoring in drug overdose. British journal of clinical pharmacology, 1999, Volume: 48, Issue:3 Topics: Acetaminophen; Anticonvulsants; Digoxin; Drug Monitoring; Drug Overdose; Ethanol; Ethylene Glycol; Humans; Iron; Lithium; Methanol; Paraquat; Prognosis; Salicylates; Theophylline	1999
Therapeutic drug monitoring in drug overdose. British journal of clinical pharmacology, 2001, Volume: 52 Suppl 1 Topics: Acetaminophen; Digoxin; Drug Monitoring; Drug Overdose; Half-Life; Humans; Metabolic Clearance Rate; Pharmacokinetics; Prognosis; Theophylline	2001
Potential interactions between exercise and drug therapy. Sports medicine (Auckland, N.Z.), 2004, Volume: 34, Issue:5 Topics: Absorption; Acetaminophen; Adrenergic beta-Antagonists; Aspirin; Digoxin; Doxycycline; Exercise; Humans; Insulin; Pharmacokinetics; Theophylline; Tissue Distribution; Verapamil; Warfarin	2004
Pharmaceutical drug overdose. Treatment guidelines from the Medical Letter, 2006, Volume: 4, Issue:49 Topics: Acetaminophen; Adrenergic beta-Antagonists; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Aspirin; Benzodiazepines; Calcium Channel Blockers; Charcoal; Digoxin; Drug Overdose; Gastric Lavage; Humans; Ipecac; Practice Guidelines as Topic; Renal Dialysis	2006
[Blood concentration useful in the diagnosis and treatment of poisoning]. Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 2014, Volume: 27, Issue:1 Topics: Acetaminophen; Aspirin; Barbiturates; Digoxin; Drug Monitoring; Humans; Inorganic Chemicals; Lithium; Organic Chemicals; Pesticides; Poisoning; Theophylline	2014

Trials

1 trial(s) available for acetaminophen and digoxin

Article	Year
Investigation of the interaction between argatroban and acetaminophen, lidocaine, or digoxin. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2002, Jul-01, Volume: 59, Issue:13 Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Antithrombins; Area Under Curve; Arginine; Confidence Intervals; Cross-Over Studies; Digoxin; Drug Interactions; Female; Half-Life; Humans; Lidocaine; Male; Metabolic Clearance Rate; Middle Aged; Pipecolic Acids; Sulfonamides	2002

Article

Year

Investigation of the interaction between argatroban and acetaminophen, lidocaine, or digoxin.

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2002, Jul-01, Volume: 59, Issue:13

Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Antithrombins; Area Under Curve; Arginine; Confidence Intervals; Cross-Over Studies; Digoxin; Drug Interactions; Female; Half-Life; Humans; Lidocaine; Male; Metabolic Clearance Rate; Middle Aged; Pipecolic Acids; Sulfonamides

2002

Other Studies

28 other study(ies) available for acetaminophen and digoxin

Article	Year
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability? Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9 Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Comparative bioavailabilities from truncated blood level curves. Journal of pharmaceutical sciences, 1975, Volume: 64, Issue:9 Topics: Acetaminophen; Aminosalicylic Acids; Biological Availability; Biopharmaceutics; Chloramphenicol; Chlordiazepoxide; Digoxin; Humans; Isoniazid; Kinetics; Pharmaceutical Preparations; Phenylbutazone; Sulfamethizole; Tetracycline; Time Factors; Warfarin	1975
Long-term diabetes alters the hepatobiliary clearance of acetaminophen, bilirubin and digoxin. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:3 Topics: Acetaminophen; Animals; Bile; Bilirubin; Diabetes Mellitus, Experimental; Digoxin; Glucuronates; Insulin; Liver; Male; Metabolic Clearance Rate; Rats; Rats, Inbred Strains; Sulfates	1992
Exposure of rats to inhalational anesthetics alters the hepatobiliary clearance of cholephilic xenobiotics. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:2 Topics: Acetaminophen; Administration, Inhalation; Anesthetics; Animals; Bile; Digoxin; Glucuronates; Liver; Male; Metabolic Clearance Rate; Protein Binding; Rats; Rats, Inbred Strains	1989
[Mechanisms of drug decomposition--drug stabilization]. Die Pharmazie, 1984, Volume: 39, Issue:9 Topics: Acetaminophen; Biotransformation; Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Digoxin; Drug Stability; Epoprostenol; Hydrogen-Ion Concentration	1984
Effects of selected drugs on serum digoxin concentration in dogs. The American journal of cardiology, 1980, Volume: 45, Issue:6 Topics: Acetaminophen; Animals; Aspirin; Digoxin; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Female; Ibuprofen; Indomethacin; Male; Metabolic Clearance Rate; Quinidine; Quinine; Time Factors	1980
Correlation of drug pharmacokinetics and effectiveness of multiple-dose activated charcoal therapy. Annals of emergency medicine, 1995, Volume: 25, Issue:3 Topics: Acetaminophen; Animals; Charcoal; Digoxin; Disease Models, Animal; Drug Administration Schedule; Female; Half-Life; Linear Models; Metabolic Clearance Rate; Pharmacokinetics; Poisoning; Poisons; Prospective Studies; Random Allocation; Swine; Theophylline; Valproic Acid	1995
Use of single-dose activated charcoal among Canadian pediatric emergency physicians. Pediatric emergency care, 2006, Volume: 22, Issue:10 Topics: Acetaminophen; Adolescent; Antidotes; Canada; Charcoal; Child, Preschool; Cross-Sectional Studies; Digoxin; Emergency Service, Hospital; Guideline Adherence; Health Care Surveys; Humans; Ibuprofen; Iron Compounds; Lorazepam; Male; Paroxetine; Poisoning; Time Factors	2006
Anthranoid laxatives influence the absorption of poorly permeable drugs in human intestinal cell culture model (Caco-2). European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2007, Volume: 66, Issue:1 Topics: Absorption; Acetaminophen; Anthraquinones; Beverages; Caco-2 Cells; Carbon Radioisotopes; Cathartics; Cell Membrane Permeability; Digoxin; Furosemide; Humans; Ketoprofen; Mannitol; Plant Leaves; Propranolol; Senna Extract; Sennosides; Verapamil	2007
Acetaminophen-induced stimulation of MDR1 expression and activity in rat intestine and in LS 174T human intestinal cell line. Biochemical pharmacology, 2011, Jan-15, Volume: 81, Issue:2 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cardiotonic Agents; Cell Line; Digoxin; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; Intestines; Male; Rats; Rats, Wistar	2011
Acetaminophen inhibits intestinal p-glycoprotein transport activity. Journal of pharmaceutical sciences, 2013, Volume: 102, Issue:10 Topics: Acetaminophen; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Cell Line, Tumor; Cyclosporins; Digoxin; Enterocytes; Hep G2 Cells; Humans; Intestinal Absorption; Intestinal Mucosa; Intestines; Male; Permeability; Rats; Rats, Wistar; Rhodamine 123; Verapamil	2013
Extracorporeal treatments in poisonings from four non-traditionally dialysed toxins (acetaminophen, digoxin, opioids and tricyclic antidepressants): A combined single-centre and national study. Basic & clinical pharmacology & toxicology, 2019, Volume: 124, Issue:3 Topics: Acetaminophen; Analgesics, Opioid; Antidepressive Agents, Tricyclic; Databases, Factual; Digoxin; Humans; New York City; Poison Control Centers; Poisoning; Renal Dialysis; Retrospective Studies; Surveys and Questionnaires; United States	2019
PBPK modeling of CYP3A and P-gp substrates to predict drug-drug interactions in patients undergoing Roux-en-Y gastric bypass surgery. Journal of pharmacokinetics and pharmacodynamics, 2020, Volume: 47, Issue:5 Topics: Acetaminophen; Administration, Oral; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; Biological Availability; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Digoxin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Gastric Bypass; Gastrointestinal Absorption; Hepatobiliary Elimination; Humans; Intestinal Elimination; Metabolic Clearance Rate; Midazolam; Models, Biological; Obesity, Morbid; Postoperative Period; Triazoles; Verapamil	2020