acetaminophen has been researched along with diethyl maleate in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (54.17) | 18.7374 |
| 1990's | 7 (29.17) | 18.2507 |
| 2000's | 4 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Piotrowski, JK; Skrzypińska-Gawrysiak, M; Sporny, S; Swietlicka, EA; Szymańska, JA | 1 |
| Furukawa, T; Palacin, M; Perez, C; Viña, J; Viña, JR | 1 |
| Jaeschke, H; Smith, CV | 1 |
| Engel, M; Hennighausen, G | 1 |
| Farber, JL; Kyle, ME; Nakae, D; Serroni, A | 1 |
| Harvison, PJ; Moldéus, P; Nelson, SD; Porubek, DJ; Rundgren, M | 1 |
| de Vries, J; Debets, AJ; van de Straat, R; Vermeulen, NP | 1 |
| Galinsky, RE | 1 |
| Acosta, D; Bruckner, JV; Mitchell, DB | 1 |
| Cho, C; Linscheer, WG; Raheja, KL | 1 |
| Di Simplicio, P; Dolara, P; Lodovici, M | 1 |
| Adams, JD; Lauterburg, BH; Mitchell, JR | 1 |
| Anundi, I; Dawson, JR; Moldéus, P; Norbeck, K | 1 |
| Lauterburg, BH; Mitchell, JR; Stillwell, WG; Vaishnav, Y | 1 |
| Harada, T; Hiraishi, H; Ito, Y; Ivey, KJ; Ogonuki, H; Razandi, M; Suzuki, Y; Terano, A | 1 |
| Brunborg, G; Holme, JA; Hongslo, JK; Smith, CV; Søderlund, EJ | 1 |
| Dalhoff, K; Poulsen, HE | 1 |
| Lauterburg, BH; Schranz, C; Speck, RF | 1 |
| Fumagalli, P; Galvani, P; Santagostino, A | 1 |
| Agarwal, R; Shukla, GS | 1 |
| Burcham, PC; Calder, IC; Nicholls-Grzemski, FA; Priestly, BG | 1 |
| Clement, YN; Dodd, CC; Kevin Park, B; Kitteringham, NR; McLellan, LI; Pirmohamed, M; Powell, H; Smith, DA; Tettey, JN | 1 |
| Feng, G; Kaplowitz, N; Matsumaru, K; Nagai, H | 1 |
| Clement, YN; Elsby, R; Goldring, CE; Hayes, JD; Itoh, K; Kitteringham, NR; McMahon, M; Park, BK; Randle, LE; Williams, DP; Yamamoto, M | 1 |
24 other study(ies) available for acetaminophen and diethyl maleate
| Article | Year |
|---|---|
Effects of 3-methylcholanthrene or diethyl maleate on the hepatotoxicity of acetaminophen.
Topics: Acetaminophen; Alanine Transaminase; Animals; Drug Synergism; Glutathione; Liver; Male; Maleates; Malondialdehyde; Methylcholanthrene; Mice; Mice, Inbred BALB C | 1992 |
Effect of oral glutathione on hepatic glutathione levels in rats and mice.
Topics: Acetaminophen; Acetylcysteine; Adenosine Triphosphate; Animals; Cysteine; Fasting; Glutathione; Liver; Maleates; Methionine; Mice; Rats; Rats, Inbred Strains | 1989 |
Effect of acetaminophen on hepatic content and biliary efflux of glutathione disulfide in mice.
Topics: Acetaminophen; Animals; Bile; Glutathione; Glutathione Disulfide; Liver; Male; Maleates; Mice; Mice, Inbred ICR | 1989 |
Depletion of hepatic glutathione in rats impairs phagocytosis in vivo.
Topics: Acetaminophen; Animals; Bromobenzenes; Glutathione; Injections, Intraperitoneal; Liver; Male; Maleates; Microspheres; Phagocytosis; Rats; Rats, Inbred Strains; Serum Albumin | 1989 |
1,3-(2-Chloroethyl)-1-nitrosourea potentiates the toxicity of acetaminophen both in the phenobarbital-induced rat and in hepatocytes cultured from such animals.
Topics: Acetaminophen; Acetone; Carmustine; Cell Survival; Deferoxamine; Drug Synergism; Enzyme Induction; Glutathione; Liver; Male; Maleates; Methylcholanthrene; Phenobarbital; Phenylenediamines | 1988 |
Investigation of mechanisms of acetaminophen toxicity in isolated rat hepatocytes with the acetaminophen analogues 3,5-dimethylacetaminophen and 2,6-dimethylacetaminophen.
Topics: Acetaminophen; Animals; Carmustine; Dithiothreitol; Glutathione; Glutathione Reductase; In Vitro Techniques; Kinetics; Lipid Peroxides; Liver; Male; Maleates; Rats; Rats, Inbred Strains | 1987 |
The mechanism of prevention of paracetamol-induced hepatotoxicity by 3,5-dialkyl substitution. The roles of glutathione depletion and oxidative stress.
Topics: Acetaminophen; Animals; Benzoquinones; Carmustine; Chemical and Drug Induced Liver Injury; Glutathione; Imines; Lipid Peroxides; Liver; Liver Diseases; Male; Maleates; Oxidation-Reduction; Quinones; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1987 |
Role of glutathione turnover in drug sulfation: differential effects of diethylmaleate and buthionine sulfoximine on the pharmacokinetics of acetaminophen in the rat.
Topics: Acetaminophen; Animals; Buthionine Sulfoximine; Glutathione; Kidney; Kinetics; Male; Maleates; Metabolic Clearance Rate; Methionine Sulfoximine; Rats; Rats, Inbred Strains; Sulfates | 1986 |
Role of glutathione depletion in the cytotoxicity of acetaminophen in a primary culture system of rat hepatocytes.
Topics: Acetaminophen; Animals; Cell Survival; Glutathione; In Vitro Techniques; Iodoacetates; Iodoacetic Acid; L-Lactate Dehydrogenase; Lipid Peroxides; Liver; Maleates; Rats; Rats, Inbred Strains | 1985 |
Prevention of acetaminophen hepatotoxicity by propylthiouracil in the glutathione depleted rat.
Topics: Acetaminophen; Animals; Free Radicals; Glutathione; Hypothyroidism; Liver; Male; Maleates; Propylthiouracil; Rats | 1983 |
Blood glutathione as a measure of exposure to toxic compounds.
Topics: Acetaminophen; Animals; Glutathione; Hydrocarbons, Iodinated; Liver; Maleates; Rats; Toxicology | 1984 |
Plasma glutathione and glutathione disulfide in the rat: regulation and response to oxidative stress.
Topics: Acetaminophen; Animals; Diquat; Glutathione; Glutathione Disulfide; Inactivation, Metabolic; Liver; Lung; Male; Maleates; Paraquat; Peroxides; Rats; Rats, Inbred Strains; tert-Butylhydroperoxide | 1983 |
The effectiveness of N-acetylcysteine in isolated hepatocytes, against the toxicity of paracetamol, acrolein, and paraquat.
Topics: Acetaminophen; Acetone; Acetylcysteine; Acrolein; Aldehydes; Amino Acids; Animals; Cell Survival; Chemical and Drug Induced Liver Injury; Glutathione; Liver; Male; Maleates; Paraquat; Phenobarbital; Rats; Rats, Inbred Strains | 1984 |
The effects of age and glutathione depletion on hepatic glutathione turnover in vivo determined by acetaminophen probe analysis.
Topics: Acetaminophen; Aging; Animals; Glutathione; Kinetics; Liver; Male; Maleates; Rats | 1980 |
Role of iron and glutathione redox cycle in acetaminophen-induced cytotoxicity to cultured rat hepatocytes.
Topics: Acetaminophen; Amitrole; Animals; Carmustine; Catalase; Cells, Cultured; Chromium Radioisotopes; Cytochrome P-450 Enzyme System; Deferoxamine; Glutathione; Glutathione Reductase; Iron; L-Lactate Dehydrogenase; Liver; Male; Maleates; Methylcholanthrene; Oxidation-Reduction; Phenanthrolines; Rats; Rats, Sprague-Dawley | 1994 |
Genotoxicity of paracetamol in mice and rats.
Topics: 4-Nitroquinoline-1-oxide; Acetaminophen; Animals; DNA; DNA Damage; DNA Repair; DNA Replication; Drug Synergism; Kidney; Liver; Male; Maleates; Mice; Mice, Inbred ICR; Mutagens; Protein Binding; Rats; Rats, Wistar | 1994 |
Synthesis rates of glutathione and activated sulphate (PAPS) and response to cysteine and acetaminophen administration in glutathione-depleted rat hepatocytes.
Topics: Acetaminophen; Animals; Cells, Cultured; Cysteine; Glutathione; Liver; Maleates; Phosphoadenosine Phosphosulfate; Rats | 1993 |
Prednisolone stimulates hepatic glutathione synthesis in mice. Protection by prednisolone against acetaminophen hepatotoxicity in vivo.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Glutathione; Liver; Male; Maleates; Mice; Mice, Inbred Strains; Prednisolone; Protein Binding | 1993 |
Glutathione depletion by xenobiotics in Coturnix coturnix japonica.
Topics: Acetaminophen; Animals; Brain; Buthionine Sulfoximine; Coturnix; Female; Glutathione; Kidney; Liver; Maleates; Xenobiotics | 1998 |
Potential role of cerebral glutathione in the maintenance of blood-brain barrier integrity in rat.
Topics: Acetaminophen; Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Blood-Brain Barrier; Brain; Curcuma; Glutathione; Ketones; Liver; Male; Maleates; Plant Extracts; Rats; Rats, Inbred Strains; Vitamin E | 1999 |
Clofibrate-induced in vitro hepatoprotection against acetaminophen is not due to altered glutathione homeostasis.
Topics: Acetaminophen; Animals; Antidotes; Cell Survival; Cells, Cultured; Chemical and Drug Induced Liver Injury; Clofibrate; Dose-Response Relationship, Drug; Drug Antagonism; Glutathione; Homeostasis; L-Iditol 2-Dehydrogenase; L-Lactate Dehydrogenase; Liver; Male; Maleates; Mice; Peroxisome Proliferators | 2000 |
Hepatocellular response to chemical stress in CD-1 mice: induction of early genes and gamma-glutamylcysteine synthetase.
Topics: Acetaminophen; Animals; Buthionine Sulfoximine; Carbon Tetrachloride; Gene Expression Regulation; Genes, fos; Genes, jun; Glutamate-Cysteine Ligase; Liver; Male; Maleates; Mice; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factor AP-1 | 2000 |
Reduced glutathione depletion causes necrosis and sensitization to tumor necrosis factor-alpha-induced apoptosis in cultured mouse hepatocytes.
Topics: Acetaminophen; Animals; Antioxidants; Apoptosis; Butylated Hydroxytoluene; Caspase Inhibitors; Caspases; Cells, Cultured; Cytochrome c Group; DNA Fragmentation; Glutathione; Hepatocytes; Ketones; Maleates; Mice; Mice, Inbred C57BL; Necrosis; NF-kappa B; Oxidative Stress; Tumor Necrosis Factor-alpha; Vitamin E | 2002 |
Activation of hepatic Nrf2 in vivo by acetaminophen in CD-1 mice.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Blotting, Northern; Cell Nucleus; DNA-Binding Proteins; Gene Expression; Glutathione; Liver; Male; Maleates; Mice; Mice, Inbred Strains; NF-E2-Related Factor 2; Trans-Activators | 2004 |