acetaminophen has been researched along with deuterium in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (27.78) | 18.7374 |
| 1990's | 4 (22.22) | 18.2507 |
| 2000's | 6 (33.33) | 29.6817 |
| 2010's | 3 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baty, JD; Robinson, PR | 2 |
| Bales, JR; Nicholson, JK; Sadler, PJ; Timbrell, JA | 1 |
| Mitoma, C; Tagg, J; Tanabe, M; Yasuda, D | 1 |
| Chan, KK; Horning, MG; Pang, KS; Waller, L | 1 |
| Caddick, S; Farrant, RD; Lindon, JC; Nicholls, AW; Nicholson, JK; Wilson, ID | 2 |
| Abramson, F; Teffera, Y | 1 |
| Christiansen, MP; Hellerstein, MK; Neese, RA; Siler, SQ | 1 |
| Cairns, ER; Dickson, SJ; Kim, ND; Speed, DJ | 1 |
| Cole, SM; Jones, JG; Malloy, CR; Sherry, AD; Solomon, MA | 1 |
| Cesar, D; Evans, WJ; Hellerstein, M; Lambert, CP; Trappe, TA; White, F | 1 |
| Burgess, SC; Dean Sherry, A; Jones, JG; Malloy, CR; Margolis, D; Merritt, ME; Smith, E; Weis, B | 1 |
| Burgess, SC; Malloy, CR; Margolis, D; Merritt, ME; Sherry, AD; Weis, BC; Wise, H | 1 |
| Baptista, C; Barosa, C; Barros, L; Bastos, M; Caldeira, MM; Carvalheiro, M; Fagulha, A; Jones, JG | 1 |
| Dansette, PM; Defoy, D; Klarskov, K; Neugebauer, W; Wagner, JR | 1 |
| Barosa, C; Basu, A; Basu, R; Jones, JG; Rizza, R | 1 |
| Barosa, C; Carvalho, F; Jones, J; Kahl, S; Roden, M | 1 |
2 trial(s) available for acetaminophen and deuterium
| Article | Year |
|---|---|
The inhibition of gluconeogenesis following alcohol in humans.
Topics: Acetaminophen; Adult; Alcohol Drinking; Blood Glucose; Deuterium; Ethanol; Fasting; Galactose; Gas Chromatography-Mass Spectrometry; Gluconeogenesis; Glucose; Glucuronates; Glycerol; Humans; Infusions, Intravenous; Kinetics; Liver; Liver Glycogen; Male; Models, Biological | 1998 |
Effect of ibuprofen and acetaminophen on postexercise muscle protein synthesis.
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Creatine Kinase; Deuterium; Double-Blind Method; Exercise; Humans; Ibuprofen; Kinetics; Male; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Placebos | 2002 |
16 other study(ies) available for acetaminophen and deuterium
| Article | Year |
|---|---|
Acetaminophen production in man after coadministration of acetanilid and phenacetin. A study with stable isotopes.
Topics: Acetaminophen; Acetanilides; Chromatography, Gas; Deuterium; Drug Combinations; Humans; Hydroxylation; Male; Mass Spectrometry; Phenacetin; Time Factors | 1977 |
Production in vitro of paracetamol from phenacetin and [2H]acetanilide: a study with stable isotopes [proceedings].
Topics: Acetaminophen; Acetanilides; Animals; Deuterium; Isotope Labeling; Liver; Male; Phenacetin; Phenobarbital; Rats | 1977 |
A high resolution proton nuclear magnetic resonance approach to the study of hepatocyte and drug metabolism. Application to acetaminophen.
Topics: Acetaminophen; Animals; Deuterium; In Vitro Techniques; Kinetics; Liver; Magnetic Resonance Spectroscopy; Rats; Rats, Inbred Strains | 1985 |
Absence of isotope effects in the microsomal hydroxylation of acetanilide.
Topics: Acetaminophen; Acetanilides; Animals; Deuterium; In Vitro Techniques; Kinetics; Liver; Microsomes; Rabbits; Tritium | 1967 |
Metabolite kinetics: formation of acetaminophen from deuterated and nondeuterated phenacetin and acetanilide on acetaminophen sulfation kinetics in the perfused rat liver preparation.
Topics: Acetaminophen; Acetanilides; Animals; Biotransformation; Deuterium; In Vitro Techniques; Kinetics; Liver; Male; Phenacetin; Rats; Rats, Inbred Strains; Sulfates | 1982 |
High resolution NMR spectroscopic studies on the metabolism and futile deacetylation of 4-hydroxyacetanilide (paracetamol) in the rat.
Topics: Acetaminophen; Acetylation; Aminophenols; Animals; Carbon Radioisotopes; Deuterium; Magnetic Resonance Spectroscopy; Models, Chemical; Rats | 1995 |
Application of high-performance liquid chromatography/chemical reaction interface mass spectrometry for the analysis of conjugated metabolites: a demonstration using deuterated acetaminophen.
Topics: Acetaminophen; Animals; Chromatography, High Pressure Liquid; Cricetinae; Deuterium; Male; Mass Spectrometry; Mesocricetus; Reproducibility of Results | 1994 |
NMR spectroscopic studies on the metabolism and futile deacetylation of phenacetin in the rat.
Topics: Acetaminophen; Acetylation; Animals; Deuterium; Magnetic Resonance Spectroscopy; Male; Phenacetin; Rats; Rats, Sprague-Dawley | 1997 |
Analysis of paracetamol using solid-phase extraction, deuterated internal standards, and gas chromatography-mass spectrometry.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Calibration; Deuterium; Gas Chromatography-Mass Spectrometry; Humans; Liver; Reference Standards; Reproducibility of Results | 2001 |
An integrated (2)H and (13)C NMR study of gluconeogenesis and TCA cycle flux in humans.
Topics: Acetaminophen; Adult; Blood Glucose; Carbon Isotopes; Citric Acid Cycle; Deuterium; Female; Gluconeogenesis; Glucose; Glutamine; Humans; Hydrogen; Kinetics; Liver; Liver Glycogen; Magnetic Resonance Spectroscopy; Male; Models, Biological; Phosphoenolpyruvate; Propionates; Reference Values; Time Factors; Water | 2001 |
Noninvasive evaluation of liver metabolism by 2H and 13C NMR isotopomer analysis of human urine.
Topics: Acetaminophen; Administration, Oral; Adult; Carbon Isotopes; Deuterium; Humans; Isomerism; Liver; Magnetic Resonance Spectroscopy; Molecular Structure; Propionates | 2003 |
Glucose production pathways by 2H and 13C NMR in patients with HIV-associated lipoatrophy.
Topics: Acetaminophen; Blood Glucose; Carbon Isotopes; Citric Acid Cycle; Deuterium; Fasting; Female; Gluconeogenesis; Glucose; Glycerol; HIV Protease Inhibitors; HIV-Associated Lipodystrophy Syndrome; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Plasma; Propionates; Water | 2004 |
Noninvasive analysis of hepatic glycogen kinetics before and after breakfast with deuterated water and acetaminophen.
Topics: Acetaminophen; Adult; Body Water; Deuterium; Diabetes Mellitus, Type 1; Fasting; Female; Food; Fructosephosphates; Glucose-6-Phosphate; Glycogen; Humans; Kinetics; Liver; Magnetic Resonance Spectroscopy; Male | 2006 |
Evaluation of deuterium labeled and unlabeled bis-methyl glutathione combined with nanoliquid chromatography-mass spectrometry to screen and characterize reactive drug metabolites.
Topics: Acetaminophen; Animals; Carbamazepine; Chromatography, High Pressure Liquid; Deuterium; Deuterium Exchange Measurement; Esterification; Glutathione; Isotope Labeling; Male; Microsomes; NADP; Nanotechnology; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization | 2011 |
Acetaminophen glucuronide and plasma glucose report identical estimates of gluconeogenesis and glycogenolysis for healthy and prediabetic subjects using the deuterated water method.
Topics: Acetaminophen; Adult; Blood Glucose; Deuterium; Female; Gluconeogenesis; Glycogenolysis; Humans; Magnetic Resonance Spectroscopy; Male; Prediabetic State; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity | 2013 |
Simplified analysis of acetaminophen glucuronide for quantifying gluconeogenesis and glycogenolysis using deuterated water.
Topics: Acetaminophen; Adult; Blood Glucose; Body Water; Deuterium; Gluconeogenesis; Glycogenolysis; Humans; Liver; Magnetic Resonance Spectroscopy; Male; Water; Young Adult | 2015 |