acetaminophen has been researched along with d-alpha tocopherol in 44 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (29.55) | 18.7374 |
| 1990's | 10 (22.73) | 18.2507 |
| 2000's | 11 (25.00) | 29.6817 |
| 2010's | 8 (18.18) | 24.3611 |
| 2020's | 2 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Strassburg, CP; Tukey, RH | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Mitchell, JR | 1 |
| Keaney, NP; Kelleher, J; Losowsky, MS; Walker, BE | 1 |
| Dixon, MF; Kelleher, J; Losowsky, MS; Walker, BE | 2 |
| Wendel, A; Werner, C | 1 |
| Inoue, K; Ito, N; Masui, T; Ogiso, T; Tsuda, H | 1 |
| Dansette, PM; Mansuy, D; Plat, M; Sassi, A | 1 |
| Dordoni, B; Gazzard, BG; Hughes, RD; Portmann, B; Williams, R | 1 |
| Stange, G | 1 |
| Hughes, H; Lauterburg, BH; Mitchell, JR; Smith, CV | 1 |
| Bartsocas, CS; Corash, L; Schulman, JD | 1 |
| McLean, AE; Tame, D; Witts, DJ | 1 |
| Corcoran, GB; Hughes, H; Lauterburg, BH; Mitchell, JR; Smith, CV | 1 |
| Ahmad, I; Suhail, M | 1 |
| Tükel, SS | 1 |
| Amimoto, T; Kajiyama, G; Koyama, SY; Matsura, T; Nakanishi, T; Yamada, K | 1 |
| Malik, NS; Meek, KM | 1 |
| Kim, SN; Kim, YC; Yoon, MY | 1 |
| Itakura, Y; Kasuga, S; Matsura, T; Sumioka, I; Yamada, K | 1 |
| Martin, FL; McLean, AE | 1 |
| Ahr, HJ; Bomhard, E; Schlüter, G; Schmidt, U | 1 |
| Agarwal, R; Shukla, GS | 1 |
| Feng, G; Kaplowitz, N; Matsumaru, K; Nagai, H | 1 |
| Ayanoğlu-Dülger, G; Sehirli, AO; Sener, G | 1 |
| El-Bahay, C; Hanelt, S; Kahl, R; Lewerenz, V; Nastevska, C; Röhrdanz, E | 1 |
| Balaji Raghavendra Rao, H; Devaki, T; Sathivel, A | 1 |
| Christopher, MM; Hill, AS; O'Neill, SL; Rogers, QR | 1 |
| Farquhar, C; Proctor, M | 1 |
| Farquhar, CM; Proctor, ML | 1 |
| Chen, HC; Chen, HT; Wu, ST; Yan, SL; Yin, MC | 1 |
| Bal, R; Koçak, A; Naziroğlu, M; Uğuz, AC | 1 |
| Forest, K; Girodet, PO; Jacquet, A; Mallet, L; Moore, N; Pariente, A | 1 |
| Ajith, TA; Janardhanan, KK; Sudheesh, NP | 1 |
| Abdel-Azeem, AS; El-Sayed, EM; Farrag, AR; Hegazy, AM; Ibrahim, KS | 1 |
| Fong, CW; Ho, HK; Saw, TY; Tan, CY | 1 |
| Degenhardt, M; Kyeremateng, SO; Lehmkemper, K; Sadowski, G | 1 |
| Abdulkhaleq, FM; Alhussainy, TM; Badr, MM; Gammoh, O; Ghanim, BY; Khalil, AAA; Qinna, NA | 1 |
| Alba, A; León-Bejarano, F; Méndez, MO; Ramírez-Elías, MG | 1 |
| Hara, S; Ito, J; Kamata, R; Karasawa, T; Kimura, H; Komada, T; Kuwata, H; Mizuta, K; Nakagawa, K; Sakuma, Y; Sampilvanjil, A; Sata, N; Takahashi, M; Watanabe, S; Yamada, N | 1 |
| Abdel-Hakeem, EA; El-Tahawy, NF; Elbassuoni, EA; Saad, AH; Saleh, NEH | 1 |
5 review(s) available for acetaminophen and d-alpha tocopherol
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Chemical nature of reactive intermediates as determinant of toxicologic responses.
Topics: Acetaminophen; Alkanes; Animals; Antioxidants; Biotransformation; Disulfides; Glutathione; Humans; Lipid Peroxides; Liver; Mice; Pharmaceutical Preparations; Rats; Vitamin E | 1982 |
Dysmenorrhoea.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drugs, Chinese Herbal; Dysmenorrhea; Female; Humans; Transcutaneous Electric Nerve Stimulation; Vitamin E | 2004 |
Dysmenorrhoea.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drugs, Chinese Herbal; Dysmenorrhea; Female; Humans; Manipulation, Spinal; Thiamine; Transcutaneous Electric Nerve Stimulation; Vitamin E | 2006 |
2 trial(s) available for acetaminophen and d-alpha tocopherol
| Article | Year |
|---|---|
Letter: Treatment of paracetamol poisoning.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Cysteamine; Humans; Injections, Intravenous; Poisoning; Prospective Studies; Rats; Time Factors; Vitamin E | 1974 |
Phytalgic, a food supplement, vs placebo in patients with osteoarthritis of the knee or hip: a randomised double-blind placebo-controlled clinical trial.
Topics: Acetaminophen; Adult; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Dietary Supplements; Double-Blind Method; Female; Fish Oils; Humans; Male; Middle Aged; Osteoarthritis; Pain; Phytotherapy; Placebos; Urtica dioica; Vitamin E | 2009 |
37 other study(ies) available for acetaminophen and d-alpha tocopherol
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Host susceptibility and acetaminophen liver injury.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Diet; Humans; Rats; Vitamin E | 1977 |
Modification of paracetamol hepatotoxicity by anti-oxidants.
Topics: Acetaminophen; Animals; Antioxidants; Liver; Male; Phenylenediamines; Propyl Gallate; Rats; Vitamin E | 1976 |
Paracetamol hepatotoxicity and vitamin E.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Female; Rats; Vitamin A Deficiency; Vitamin E | 1976 |
Hepatic uptake and antihepatotoxic properties of vitamin E and liposomes in the mouse.
Topics: Acetaminophen; Animals; Benzo(a)pyrene; Chemical and Drug Induced Liver Injury; Drug Carriers; Galactosamine; Lipopolysaccharides; Liposomes; Liver; Male; Mice; Phosphatidylcholines; Vitamin E | 1990 |
Inhibitory effects of ethoxyquin, 4,4'-diaminodiphenylmethane and acetaminophen on rat hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Acetaminophen; Aniline Compounds; Animals; Body Weight; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Diethylnitrosamine; Eating; Ethoxyquin; Glutathione; Liver Neoplasms, Experimental; Male; Quinolines; Rats; Rats, Inbred F344; Vitamin E | 1986 |
A new potent inhibitor of lipid peroxidation in vitro and in vivo, the hepatoprotective drug anisyldithiolthione.
Topics: Acetaminophen; Anethole Trithione; Anisoles; Antioxidants; Carbon Tetrachloride Poisoning; Ethane; Levamisole; Lipid Peroxides; Vitamin E | 1986 |
Vitamin E protection of the liver from paracetamol in the rat.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Female; Liver; Liver Cirrhosis; Rats; Vitamin E; Vitamin E Deficiency | 1974 |
Protection of rats against the hepatotoxic effect of paracetamol.
Topics: Acetaminophen; Administration, Oral; Animals; Cysteamine; Cytochrome P-450 Enzyme System; Drug Interactions; Glutathione; Injections, Intraperitoneal; Liver; Male; Microsomes, Liver; Necrosis; Propranolol; Rats; Thioctic Acid; Vitamin E | 1974 |
[On the therapy of impairment and loss of hearing].
Topics: Acetaminophen; Bicarbonates; Deafness; Hearing Disorders; Hearing Tests; Humans; Nicotinic Acids; Theophylline; Turpentine; Vitamin A; Vitamin B Complex; Vitamin E | 1967 |
Can acetaminophen cause hemolysis in G6PD deficiency?
Topics: Acetaminophen; Adult; Anemia, Hemolytic; Glucosephosphate Dehydrogenase Deficiency; Hemolysis; Humans; Male; Vitamin E | 1982 |
The influence of nutrition and inducers on mechanisms of toxicity in humans and animals.
Topics: Acetaminophen; Animals; Anticonvulsants; Calcium; Carcinogens; Cytochrome P-450 Enzyme System; Epilepsy; Food Additives; Humans; Liver; Nutritional Physiological Phenomena; Phenobarbital; Rats; Toxicology; Vitamin E | 1980 |
Alkylation and peroxidation injury from chemically reactive metabolites.
Topics: Acetaminophen; Acetylcysteine; Alkylation; Animals; Antioxidants; Biotransformation; Drug-Related Side Effects and Adverse Reactions; Glutathione; Glutathione Disulfide; Humans; Lipid Peroxides; Liver; Microsomes, Liver; Peroxides; Pharmaceutical Preparations; Vitamin E | 1981 |
In vivo effects of acetaminophen on rat RBC and role of vitamin E.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Erythrocytes; Male; Rats; Vitamin E | 1995 |
Effects of acetaminophen on methemoglobin, superoxide dismutase and Na(+)-K+ ATPase activities of human erythrocytes.
Topics: Acetaminophen; Dose-Response Relationship, Drug; Erythrocytes; Humans; Methemoglobin; Oxidation-Reduction; Sodium-Potassium-Exchanging ATPase; Superoxide Dismutase; Vitamin D; Vitamin E | 1995 |
Acetaminophen-induced hepatic injury in mice: the role of lipid peroxidation and effects of pretreatment with coenzyme Q10 and alpha-tocopherol.
Topics: Acetaminophen; Alanine Transaminase; Animals; Coenzymes; Glutathione; Lipid Peroxidation; Liver; Liver Diseases; Male; Mice; Mice, Inbred ICR; Oxidation-Reduction; Thiobarbituric Acid Reactive Substances; Ubiquinone; Vitamin E | 1995 |
Vitamins and analgesics in the prevention of collagen ageing.
Topics: Acetaminophen; Aged; Aging; Anti-Inflammatory Agents, Non-Steroidal; Ascorbic Acid; Aspirin; Cellular Senescence; Chelating Agents; Collagen; Cornea; Culture Techniques; Enzyme Inhibitors; Glycosylation; Guanidines; Humans; Ibuprofen; Pentetic Acid; Sclera; Vitamin E; Vitamins | 1996 |
Potentiation of acetaminophen hepatotoxicity by acute physical exercise in rats.
Topics: Acetaminophen; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alanine Transaminase; Analgesics; Animals; Aspartate Aminotransferases; Dose-Response Relationship, Drug; Female; Glutathione; Lipid Peroxidation; Liver; Malondialdehyde; Physical Conditioning, Animal; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Time Factors; Vitamin E; Yohimbine | 1997 |
Mechanisms of protection by S-allylmercaptocysteine against acetaminophen-induced liver injury in mice.
Topics: Acetaminophen; Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Coenzymes; Cysteine; Cytochrome P-450 CYP2E1; Glucuronosyltransferase; Glutathione; Lipid Peroxidation; Liver; Liver Diseases; Male; Mice; Proteins; Sulfhydryl Compounds; Sulfotransferases; Ubiquinone; Vitamin E | 1998 |
Comparison of paracetamol-induced hepatotoxicity in the rat in vivo with progression of cell injury in vitro in rat liver slices.
Topics: Acetaminophen; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cytochrome P-450 Enzyme System; Enzyme Activation; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Male; Models, Biological; Necrosis; Phenobarbital; Rats; Rats, Wistar; Time Factors; Vitamin E | 1998 |
Acarbose and acetaminophen: a dangerous combination?
Topics: Acarbose; Acetaminophen; Animals; Drug Synergism; Female; Glutathione; Hypoglycemic Agents; Lipid Peroxidation; Liver; Rats; Rats, Sprague-Dawley; Trisaccharides; Vitamin A; Vitamin E | 1999 |
Potential role of cerebral glutathione in the maintenance of blood-brain barrier integrity in rat.
Topics: Acetaminophen; Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Blood-Brain Barrier; Brain; Curcuma; Glutathione; Ketones; Liver; Male; Maleates; Plant Extracts; Rats; Rats, Inbred Strains; Vitamin E | 1999 |
Reduced glutathione depletion causes necrosis and sensitization to tumor necrosis factor-alpha-induced apoptosis in cultured mouse hepatocytes.
Topics: Acetaminophen; Animals; Antioxidants; Apoptosis; Butylated Hydroxytoluene; Caspase Inhibitors; Caspases; Cells, Cultured; Cytochrome c Group; DNA Fragmentation; Glutathione; Hepatocytes; Ketones; Maleates; Mice; Mice, Inbred C57BL; Necrosis; NF-kappa B; Oxidative Stress; Tumor Necrosis Factor-alpha; Vitamin E | 2002 |
Protective effects of melatonin, vitamin E and N-acetylcysteine against acetaminophen toxicity in mice: a comparative study.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Blood Urea Nitrogen; Creatinine; Kidney; Liver; Melatonin; Mice; Vitamin E | 2003 |
Antioxidants protect primary rat hepatocyte cultures against acetaminophen-induced DNA strand breaks but not against acetaminophen-induced cytotoxicity.
Topics: Acetaminophen; Acetylcysteine; alpha-Tocopherol; Analgesics, Non-Narcotic; Animals; Antioxidants; Blotting, Northern; Cell Death; Chemical and Drug Induced Liver Injury; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Formazans; Hepatocytes; Lipid Peroxides; Liver Diseases; Male; Neutral Red; Rats; Rats, Wistar; RNA; Silybin; Silymarin; Tetrazolium Salts | 2003 |
Antihepatotoxic nature of Ulva reticulata (Chlorophyceae) on acetaminophen-induced hepatoxicity in experimental rats.
Topics: Acetaminophen; Administration, Oral; Alanine Transaminase; Animals; Antioxidants; Ascorbic Acid; Aspartate Aminotransferases; Catalase; Free Radical Scavengers; Glutathione; Lipid Peroxidation; Liver; Male; Oxidative Stress; Plant Extracts; Rats; Rats, Wistar; Superoxide Dismutase; Ulva; Vitamin E | 2004 |
Effects of dietary antioxidant supplementation before and after oral acetaminophen challenge in cats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetaminophen; Analgesics, Non-Narcotic; Animals; Antioxidants; Biomarkers; Cats; Chromatography, High Pressure Liquid; Cysteine; Dietary Supplements; Drug Therapy, Combination; Female; Glutathione; Guanine; Lymphocyte Activation; Lymphocytes; Male; Methemoglobin; Thioctic Acid; Vitamin E | 2005 |
Protective effects from carnosine and histidine on acetaminophen-induced liver injury.
Topics: Acetaminophen; alpha-Tocopherol; Animals; Ascorbic Acid; Carnosine; Catalase; Chemical and Drug Induced Liver Injury; Chemokine CCL2; Cytochrome P-450 CYP2E1; Glutathione; Glutathione Peroxidase; Histidine; Interleukins; Lipid Peroxidation; Liver; Mice; Mice, Inbred BALB C; Protective Agents; RNA, Messenger; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2009 |
Acetaminophen at different doses protects brain microsomal Ca2+-ATPase and the antioxidant redox system in rats.
Topics: Acetaminophen; Animals; beta Carotene; Brain; Calcium; Glutathione Peroxidase; Lipid Peroxidation; Male; Microsomes; Oxidative Stress; Rats; Rats, Wistar; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Vitamin A; Vitamin E | 2009 |
Hepatoprotective effects of DL-α-lipoic acid and α-Tocopherol through amelioration of the mitochondrial oxidative stress in acetaminophen challenged rats.
Topics: Acetaminophen; alpha-Tocopherol; Animals; Lipid Peroxidation; Male; Mitochondria; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Thioctic Acid | 2013 |
Hepatoprotective, antioxidant, and ameliorative effects of ginger (Zingiber officinale Roscoe) and vitamin E in acetaminophen treated rats.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Antioxidants; Aspartate Aminotransferases; Bilirubin; Blood Proteins; Chemical and Drug Induced Liver Injury; Lipid Peroxidation; Liver; Male; Malondialdehyde; Necrosis; Oxidative Stress; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Triglycerides; Vitamin E; Zingiber officinale | 2013 |
Comparative hepatoprotective effects of tocotrienol analogs against drug-induced liver injury.
Topics: Acetaminophen; Animals; Antioxidants; bcl-X Protein; Caspase 3; Cell Line, Transformed; Cell Survival; Gene Expression Regulation; Hepatocytes; Hydrogen Peroxide; Interleukin-6; Lipid Peroxidation; Mice; Mitochondria; Nitric Oxide Synthase Type II; Oxidative Stress; Proliferating Cell Nuclear Antigen; Protective Agents; Reactive Oxygen Species; Signal Transduction; Tocopherols; Tumor Necrosis Factor-alpha; Vitamin E | 2015 |
Influence of Low-Molecular-Weight Excipients on the Phase Behavior of PVPVA64 Amorphous Solid Dispersions.
Topics: Acetaminophen; Administration, Oral; alpha-Tocopherol; Chemistry, Pharmaceutical; Excipients; Humans; Models, Molecular; Molecular Weight; Naproxen; Phase Transition; Polyethylene Glycols; Pyrrolidines; Solubility; Thermodynamics; Transition Temperature; Vinyl Compounds | 2018 |
Antioxidative stress effects of vitamins C, E, and B
Topics: Acetaminophen; Animals; Antioxidants; Ascorbic Acid; Chemical and Drug Induced Liver Injury; Liver; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Vitamin B 12; Vitamin E | 2018 |
Improved Vancouver Raman Algorithm Based on Empirical Mode Decomposition for Denoising Biological Samples.
Topics: Acetaminophen; Algorithms; Animals; Brain; Humans; Mice; Nails; Polytetrafluoroethylene; Signal Processing, Computer-Assisted; Specimen Handling; Spectrum Analysis, Raman; Vitamin E | 2019 |
Ferroptosis driven by radical oxidation of n-6 polyunsaturated fatty acids mediates acetaminophen-induced acute liver failure.
Topics: Acetaminophen; alpha-Tocopherol; Animals; Antioxidants; Coenzyme A Ligases; Cyclohexylamines; Cyclooxygenase 2; Deferoxamine; Disease Models, Animal; Fatty Acids, Omega-6; Ferroptosis; Hepatocytes; Humans; Iron Chelating Agents; Lipid Peroxidation; Liver; Liver Failure, Acute; Mice, Inbred C57BL; Mice, Knockout; Oxidation-Reduction; Phenylenediamines | 2020 |
Potential benefits of using hydrogen sulfide, vitamin E and necrostatin-1 to counteract acetaminophen‑induced hepatotoxicity in rats.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; COVID-19; Humans; Hydrogen Sulfide; Imidazoles; Indoles; Liver; Male; Oxidative Stress; Rats; SARS-CoV-2; Vitamin E | 2021 |