acetaminophen has been researched along with cysteamine in 81 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 72 (88.89) | 18.7374 |
1990's | 2 (2.47) | 18.2507 |
2000's | 3 (3.70) | 29.6817 |
2010's | 4 (4.94) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Scott, CR; Stewart, MJ | 1 |
Douglas, AP; James, O; Lesna, M; Pulman, L; Roberts, SH; Smith, PA; Watson, AJ | 1 |
Douglas, AP; Hamlyn, AN; James, O | 1 |
Park, J; Prescott, LF; Proudfoot, AT | 2 |
Hughes, RD; Trewby, P; Williams, R | 1 |
Park, J; Prescott, LF; Proudfoot, AT; Smith, IJ; Sutherland, GR | 1 |
Barclay, JE; Stewart, MJ | 1 |
Brouwers, JR; Vermeij, P | 1 |
Adriaenssens, P; Ballantyne, A; Park, J; Prescott, LF; Proudfoot, AT | 1 |
Bhakthan, NM; Chiu, S | 1 |
Allain, P; Chaleil, D; Larra, F | 1 |
Harvey, FD; Levitt, TE | 1 |
Davis, M; Williams, R | 1 |
Ameer, B; Greenblatt, DJ | 1 |
Bennet, JR; Davis, M; Gazzard, BG; Hanid, MA; Hughes, RD; Murray-Lyon, IM; Trewby, PN; Williams, R | 1 |
Black, M | 2 |
van Zwieten, PA | 1 |
Adam, RD; Critchley, JA; Illingworth, RN; Prescott, LF; Proudfoot, AT; Stewart, MJ | 1 |
Gilbertson, AA; Hall, SM; Roberts, WO; Smith, JM; White, TA | 1 |
Prescott, LF; Proudfoot, AT; Stewart, MJ | 1 |
Peterson, RG; Rumack, BH | 1 |
Prescott, LF | 2 |
Cheung, TP; Parkin, GW; Rigby, RJ; Thomson, NM | 1 |
Austin, F; Carloss, H; Forrester, J; Fuson, T | 1 |
Emby, DJ; Fraser, BN | 1 |
Best, L; Krenzelok, EP; Manoguerra, AS | 1 |
Cameron, AJ; Szabo, S | 1 |
Forester, D | 1 |
Davis, M; Gazzard, BG; Goulding, R; Hughes, RD; Widdop, B; Williams, R | 1 |
Hart, FE; Willson, RA | 1 |
Birrell, R; Briggs, JD; Henry, DA; Knepil, J; Solomon, AE; Winchester, JF | 1 |
Douzeen, JM; Pikaar, SA; van Heijst, AN | 1 |
Crome, P; Vale, JA; Volans, GN; Widdop, P | 1 |
Moerland, J | 1 |
James, O | 1 |
Gazzard, BG; Hughes, RD; Murray-Lyon, IM; Williams, RS | 1 |
Labadarios, D; Williams, RS | 1 |
Penn, RG | 1 |
Bennett, JR; Chhibber, AD; Dordoni, B; Gazzard, BG; Hughes, RD; Murray-Lyon, IM; Williams, R | 1 |
Prescott, LF; Wright, N | 2 |
Matthew, H; Rumack, BH | 1 |
Alván, G; Evaldsson-Carlén, U; Mellström, B | 1 |
Brown, IR; Peterson, TC | 1 |
Peterson, MR; Peterson, TC; Williams, CN | 1 |
Gregus, Z; Klaassen, CD; Madhu, C | 1 |
Davis, M | 1 |
Hayashi, S; Nakai, T | 1 |
Jollow, DJ; Miller, MG | 1 |
Forrest, AR; Matthew, H; Newton, RW; Prescott, LF; Swainson, CP; Wright, N | 1 |
Goulding, R; Harvey, F | 1 |
Jollow, DJ; Keiser, H; Mitchell, JR; Potter, WZ; Thorgeirsson, SS | 1 |
Dordoni, B; Gazzard, BG; Hughes, RD; Portmann, B; Williams, R | 1 |
Schütt, A; Siegers, CP; Strubelt, O | 1 |
Gilbertson, AA; Smith, JM | 1 |
Crome, P; Hamlyn, AN; Lesna, M; Meredith, T; Record, CO; Smith, PA; Volans, GN; Watson, AJ | 1 |
Critchley, JA; Prescott, LF | 1 |
Birkett, DJ; Drew, R; Miners, JO | 1 |
Harris, AL | 1 |
Goulding, R; Meredith, TJ | 1 |
Pflüger, KH | 1 |
Davis, M; Smith, HM; Tredger, JM; Williams, R | 1 |
Gillette, JR | 1 |
Johansson, L; Lindvall, S; Rydell, G; Svensson, BE; Ulff, B | 1 |
Beger, RD; Holland, RD; Koza-Taylor, PH; Lawton, MP; Manautou, JE; Moffit, JS; Thibodeau, MS | 1 |
Koyama, R; Mizuta, R | 1 |
Brok, J; Buckley, NA; Chiew, AL; Gluud, C | 1 |
9 review(s) available for acetaminophen and cysteamine
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Acetaminophen.
Topics: Acetaminophen; Analgesia; Animals; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Cysteamine; Double-Blind Method; Fever; Hemostasis; Humans; Kidney Diseases; Kinetics; Liver; Male; Methionine; Pain; Placebos | 1977 |
Hepatotoxicity: pathogenesis and therapeutic intervention.
Topics: Acetaminophen; Anabolic Agents; Androgens; Animals; Chemical and Drug Induced Liver Injury; Cysteamine; Cysteine; Erythromycin; Estrogens; Halothane; Humans; Isoniazid; Liver; Nitrofurantoin; Rifampin | 1979 |
Protective agents for acetaminophen overdose.
Topics: Acetaminophen; Acetylcysteine; Animals; Cell Membrane; Chemical and Drug Induced Liver Injury; Cimetidine; Cysteamine; Glucuronates; Glutathione; Humans; Inactivation, Metabolic; Lipid Peroxides; Liver; Methionine; Necrosis; Propylthiouracil | 1986 |
[Therapy of toxic hepatitis].
Topics: Acetaminophen; Acetylcysteine; Adrenal Cortex Hormones; Age Factors; Aged; Animals; Chemical and Drug Induced Liver Injury; Cysteamine; Female; Humans; Male; Middle Aged; Prognosis; Sex Factors | 1985 |
The treatment of acetaminophen poisoning.
Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Antidotes; Aspartate Aminotransferases; Biotransformation; Chemical and Drug Induced Liver Injury; Cysteamine; Glutathione; Humans; Liver; Methionine; Necrosis; Sulfhydryl Compounds | 1983 |
Acetaminophen hepatotoxicity.
Topics: Acetaminophen; Acetylcysteine; Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Cysteamine; Cysteine; Glutathione; Hepatic Encephalopathy; Humans; Liver; Liver Function Tests; Methionine | 1980 |
Paracetamol.
Topics: Acetaminophen; Acetylcysteine; Adult; Animals; Chemical and Drug Induced Liver Injury; Child; Cysteamine; Dextropropoxyphene; Humans; Infant; Kidney Diseases; Methionine | 1980 |
Interventions for paracetamol (acetaminophen) overdose.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antidotes; Charcoal; Cysteamine; Dimercaprol; Drug Overdose; Gastric Lavage; Humans; Intestinal Absorption; Liver Failure, Acute; Liver Transplantation; Methionine; Randomized Controlled Trials as Topic | 2018 |
10 trial(s) available for acetaminophen and cysteamine
Article | Year |
---|---|
Controlled trial of cysteamine in treatment of acute paracetamol (acetaminophen) poisoning.
Topics: Acetaminophen; Acute Disease; Adult; Age Factors; Aged; Aspartate Aminotransferases; Bile Acids and Salts; Bilirubin; Clinical Trials as Topic; Cysteamine; Ferritins; Humans; Injections, Intravenous; Liver; Liver Function Tests; Prothrombin; Time Factors | 1976 |
Acetaminophen.
Topics: Acetaminophen; Analgesia; Animals; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Cysteamine; Double-Blind Method; Fever; Hemostasis; Humans; Kidney Diseases; Kinetics; Liver; Male; Methionine; Pain; Placebos | 1977 |
Controlled trial of cysteamine and dimercaprol after paracetamol overdose.
Topics: Acetaminophen; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Cysteamine; Dimercaprol; Female; Humans; Male | 1977 |
A controlled trial of cysteamine in the treatment of acute paracetamol poisoning.
Topics: Acetaminophen; Acute Disease; Adult; Cysteamine; Humans; Liver; Liver Function Tests; Suicide | 1976 |
The use of cysteamine and dimercaprol.
Topics: Acetaminophen; Cysteamine; Dimercaprol; Humans; Liver; Liver Function Tests | 1976 |
Proceedings: Controlled trial of cysteamine and dimercaprol in the prevention of liver damage after paracetamol overdose.
Topics: Acetaminophen; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Cysteamine; Dimercaprol; Humans; Liver | 1975 |
Letter: Treatment of paracetamol poisoning.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Cysteamine; Humans; Injections, Intravenous; Poisoning; Prospective Studies; Rats; Time Factors; Vitamin E | 1974 |
Letter: Cysteamine for paracetamol overdosage.
Topics: Acetaminophen; Acetylcysteine; Blood Specimen Collection; Chemical and Drug Induced Liver Injury; Chromatography, Gas; Clinical Trials as Topic; Cysteamine; Dimercaprol; Humans; Penicillamine; Poisoning; Time Factors | 1974 |
Letter: Treatment of paracetamol overdosage.
Topics: Acetaminophen; Administration, Oral; Clinical Trials as Topic; Cysteamine; Humans; Methionine; Poisoning; Time Factors | 1974 |
Methionine and cysteamine in paracetamol (acetaminophen) overdose, prospective controlled trial of early therapy.
Topics: Acetaminophen; Amylases; Clinical Trials as Topic; Cysteamine; Humans; Kidney; Liver; Methionine; Myocardium; Prospective Studies | 1981 |
63 other study(ies) available for acetaminophen and cysteamine
Article | Year |
---|---|
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Letter: cysteamine treatment in paracetamol overdose.
Topics: Acetaminophen; Adult; Alcohol Drinking; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cysteamine; Ethanol; Gastric Lavage; Humans; Liver Diseases; Male; Time Factors | 1975 |
Liver damage after paracetamol overdose. Comparison of liver-function tests, fasting serum bile acids, and liver histology.
Topics: Acetaminophen; Adolescent; Adult; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Cysteamine; Humans; Liver; Liver Function Tests; Middle Aged; Parenteral Nutrition | 1975 |
Letter: Cysteamine for paracetamol poisoning.
Topics: Acetaminophen; Cysteamine; Humans; Time Factors | 1976 |
Letter: Cysteamine for paracetamol poisoning.
Topics: Acetaminophen; Cysteamine; Humans; Time Factors | 1976 |
Cysteamine, methionine, and penicillamine in the treatment of paracetamol poisoning.
Topics: Acetaminophen; Acute Kidney Injury; Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Cysteamine; Drug Evaluation; Female; Humans; Liver Diseases; Male; Methionine; Middle Aged; Necrosis; Penicillamine; Poisoning; Time Factors | 1976 |
Letter: Treatment of paracetamol overdose.
Topics: Acetaminophen; Cysteamine; Drug Evaluation; Humans; Methionine; Suicide, Attempted | 1976 |
Letter: Emergency estimation of plasma-paracetamol.
Topics: Acetaminophen; Colorimetry; Cysteamine; Emergencies; Humans; Poison Control Centers | 1976 |
Cysteamine injection for paracetamol poisoning.
Topics: Acetaminophen; Cysteamine; Humans; Injections | 1976 |
Treatment of paracetamol (acetaminophen) poisoning with N-acetylcysteine.
Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Chemical and Drug Induced Liver Injury; Cysteamine; Drug Evaluation; Female; Follow-Up Studies; Humans; Infusions, Parenteral; Male; Methionine; Middle Aged | 1977 |
Experimental acetaminophen-induced hepatic necrosis: biochemical and electron microscopic study of cysteamine protection.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cricetinae; Cysteamine; Electron Transport; Lipid Metabolism; Liver Diseases; Male; Mesocricetus; Microscopy, Electron; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Necrosis; Peroxides | 1978 |
[Radioprotective action of N-acetyl p. aminophenol in the mouse].
Topics: Acetaminophen; Animals; Cell Survival; Cysteamine; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Gamma Rays; Injections, Intraperitoneal; Leukocytes; Male; Mice; Radiation Effects; Radiation-Protective Agents | 1975 |
Experimental evaluation of paracetamol antidotes.
Topics: Acetaminophen; Animals; Antidotes; Bile; Cysteamine; Cysteine; Ditiocarb; Glutathione; Imidazoles; In Vitro Techniques; Liver; Methionine; Mice; Rats | 1976 |
Therapeutic aspects of paracetamol overdose including management of acute liver failure.
Topics: Acetaminophen; Chemical and Drug Induced Liver Injury; Cysteamine; Humans; Tiopronin | 1977 |
[Therapy of paracetamol poisoning].
Topics: Acetaminophen; Acetylcysteine; Chemical and Drug Induced Liver Injury; Cysteamine; Humans; Methionine | 1979 |
Intravenous N-acetylcystine: the treatment of choice for paracetamol poisoning.
Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Cysteamine; Female; Humans; Infusions, Parenteral; Kidney Diseases; Liver Diseases; Male; Methionine; Middle Aged; Risk; Time Factors | 1979 |
Paracetamol overdosage.
Topics: Acetaminophen; Acetylcysteine; Cysteamine; Humans | 1978 |
Late treatment of paracetamol poisoning with mercaptamine.
Topics: Acetaminophen; Acute Kidney Injury; Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Cysteamine; Female; Humans; Liver Diseases; Liver Function Tests; Male; Middle Aged; Time Factors | 1978 |
Cysteamine or N-acetylcysteine for paracetamol poisoning?
Topics: Acetaminophen; Acetylcysteine; Cysteamine; Humans; Time Factors | 1978 |
Toxicity of acetaminophen overdose.
Topics: Acetaminophen; Acetylcysteine; Cysteamine; Humans; Methionine | 1978 |
The chief scientist reports ... prevention of hepatic necrosis following paracetamol overdosage.
Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Cysteamine; Female; Humans; Liver Diseases; Male; Methionine; Middle Aged; Scotland | 1978 |
The treatment of paracetamol overdose with charcoal haemoperfusion and cysteamine.
Topics: Acetaminophen; Charcoal; Cysteamine; Female; Hemoperfusion; Humans; Middle Aged; Poisoning | 1978 |
Acute acetaminophen intoxication.
Topics: Acetaminophen; Acetylcysteine; Adult; Chemical and Drug Induced Liver Injury; Cysteamine; Female; Humans; Liver; Male; Methionine; Suicide, Attempted | 1978 |
Hepatotoxicity of paracetamol enhanced by ingestion of alcohol: report of two cases.
Topics: Acetaminophen; Adult; Alcoholism; Chemical and Drug Induced Liver Injury; Cysteamine; Female; Humans; Liver Diseases; Male; Middle Aged; Necrosis | 1977 |
Acetaminophen toxity.
Topics: Acetaminophen; Acetylcysteine; Adult; Chemical and Drug Induced Liver Injury; Cysteamine; Humans; Liver; Liver Diseases; Liver Function Tests; Male; Necrosis; Sulfhydryl Compounds | 1977 |
Acetaminophen (paracetamol) poisoning: gastrointestinal side effects of cysteamine and their possible cause and treatment.
Topics: Acetaminophen; Antidotes; Cysteamine; Humans; Poisoning | 1977 |
Acetaminophen hepatotoxicity.
Topics: Acetaminophen; Chemical and Drug Induced Liver Injury; Cysteamine; Humans; Methionine | 1977 |
Early prediction of the outcome of a paracetamol overdose based on an analysis of 163 patients.
Topics: Acetaminophen; Bilirubin; Chemical and Drug Induced Liver Injury; Cysteamine; Humans; Liver Diseases; Liver Function Tests; Prognosis | 1977 |
Treatment of acute paracetamol poisoning.
Topics: Acetaminophen; Chemical and Drug Induced Liver Injury; Cysteamine; Humans; Liver Diseases | 1977 |
In vitro spectral alteration of hepatic cytochrome P-450 by experimental drug injury.
Topics: Acetaminophen; Animals; Buffers; Chemical and Drug Induced Liver Injury; Cysteamine; Cysteine; Cytochrome P-450 Enzyme System; Dimethyl Sulfoxide; Enzyme Induction; Glutathione; In Vitro Techniques; Liver Diseases; Male; Methionine; Microsomes, Liver; Phenobarbital; Rats; Solvents | 1977 |
Therapeutic comparison of thiol compounds in severe paracetamol poisoning.
Topics: Acetaminophen; Adolescent; Adult; Amino Acids; Cysteamine; Female; Humans; Liver Function Tests; Male; Substance-Related Disorders | 1977 |
[Paracetamol poisoning].
Topics: Acetaminophen; Administration, Oral; Adult; Cysteamine; Female; Humans; Injections, Intravenous; Legislation, Drug; Methionine; Netherlands; Poisoning | 1976 |
Letter: Toxicity of paracetamol in children.
Topics: Acetaminophen; Child; Child, Preschool; Cysteamine; Humans; Methionine | 1976 |
[Paracetamol poisoning--liver damage. Therapy or prevention?].
Topics: Acetaminophen; Chemical and Drug Induced Liver Injury; Cysteamine; Glutathione; Humans; Liver | 1976 |
Cysteamine, L-methionine and D-penicillamine in paracetamol poisoning.
Topics: Acetaminophen; Cysteamine; Humans; Methionine; Penicillamine | 1976 |
Paracetamol, alpha-mercaptopropionyl glycine and some observations on the toxicity of protective agents.
Topics: Acetaminophen; Amino Acids, Sulfur; Animals; Cysteamine; Glutathione; Liver; Male; Mice; Tiopronin | 1976 |
A theoretical approach to the management of paracetamol overdosage.
Topics: Acetaminophen; Charcoal; Cysteamine; Drug Therapy; Glutathione; Humans; Perfusion; Propranolol; Renal Dialysis; Sulfhydryl Compounds | 1976 |
Editorial: Paracetamol and the liver.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cysteamine; Humans; Liver; Liver Diseases; Necrosis | 1976 |
Letter: Treatment of paracetamol poisoning.
Topics: Acetaminophen; Cysteamine; Humans; Poisoning | 1975 |
Acetaminophen poisoning and toxicity.
Topics: Acetaminophen; Agranulocytosis; Chemical and Drug Induced Liver Injury; Cysteamine; Humans; Hypoglycemia; Kidney Papillary Necrosis; Liver; Necrosis; Pericarditis; Poison Control Centers; Poisoning; Prognosis; Skin Manifestations; Substance-Related Disorders | 1975 |
[Paracetamol poisoning--clinical picture and treatment possibilities].
Topics: Acetaminophen; Adult; Antidotes; Chemical and Drug Induced Liver Injury; Cysteamine; Cysteine; Drug Synergism; Female; Humans; Liver; Methionine; Oxazepam | 1976 |
Cysteamine in combination with N-acetylcysteine prevents acetaminophen-induced hepatotoxicity.
Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Animals; Cysteamine; Cytochrome P-450 Enzyme System; Drug Interactions; Liver; Male; Mice | 1992 |
The role of heme oxygenase and aryl hydrocarbon hydroxylase in the protection by cysteamine from acetaminophen hepatotoxicity.
Topics: Acetaminophen; Animals; Aryl Hydrocarbon Hydroxylases; Cysteamine; Cytochrome P-450 Enzyme Inhibitors; Heme Oxygenase (Decyclizing); Liver; Male; Mixed Function Oxygenases; Rats; Rats, Inbred Strains | 1989 |
Biliary excretion of acetaminophen-glutathione as an index of toxic activation of acetaminophen: effect of chemicals that alter acetaminophen hepatotoxicity.
Topics: Acetaminophen; Animals; Antioxidants; Bile; Biotransformation; Cricetinae; Cysteamine; Liver; Male; Mesocricetus; Methylcholanthrene; Phenobarbital; Prostaglandin Antagonists | 1989 |
Acetaminophen hepatotoxicity: studies on the mechanism of cysteamine protection.
Topics: Acetaminophen; Animals; Cricetinae; Cysteamine; In Vitro Techniques; Inactivation, Metabolic; Kinetics; Liver; Male; Mesocricetus; Necrosis | 1986 |
Successful treatment of severe paracetamol overdosage with cysteamine.
Topics: Acetaminophen; Adolescent; Adult; Bilirubin; Blood Cell Count; Blood Urea Nitrogen; Chemical and Drug Induced Liver Injury; Chromatography, Gas; Cysteamine; Dose-Response Relationship, Drug; Female; Humans; Injections, Intravenous; Liver Diseases; Middle Aged; Poisoning; Prothrombin Time; Spectrophotometry; Suicide | 1974 |
Letter: Action of cysteamine in paracetamol poisoning.
Topics: Acetaminophen; Animals; Biotransformation; Cysteamine; Liver; Oxidation-Reduction; Perfusion; Rats | 1974 |
Letter: B.A.L. in paracetamol poisoning.
Topics: Acetaminophen; Chemical and Drug Induced Liver Injury; Cysteamine; Dimercaprol; Drug Evaluation; Humans; Injections, Intramuscular | 1974 |
Acetaminophen-induced hepatic injury: protective role of glutathione in man and rationale for therapy.
Topics: Acetaminophen; Acetylcysteine; Adult; Amobarbital; Animals; Chemical and Drug Induced Liver Injury; Chromatography, Paper; Cysteamine; Cytochrome P-450 Enzyme System; Desipramine; Dimercaprol; Dose-Response Relationship, Drug; Enzyme Induction; Female; Glutathione; Humans; Indicators and Reagents; Liver; Male; Mass Spectrometry; Methyltransferases; Mice; Microsomes, Liver; Phenobarbital; Protein Binding; Proteins; Sulfhydryl Compounds; Time Factors; Tritium | 1974 |
Protection of rats against the hepatotoxic effect of paracetamol.
Topics: Acetaminophen; Administration, Oral; Animals; Cysteamine; Cytochrome P-450 Enzyme System; Drug Interactions; Glutathione; Injections, Intraperitoneal; Liver; Male; Microsomes, Liver; Necrosis; Propranolol; Rats; Thioctic Acid; Vitamin E | 1974 |
The curative effects of cysteamine, cysteine, and dithiocarb in experimental paracetamol poisoning.
Topics: Acetaminophen; Alcohols; Animals; Carboxylic Acids; Chemical and Drug Induced Liver Injury; Cysteamine; Cysteine; Dimercaprol; Enzymes; Flavonoids; Glutathione; Lethal Dose 50; Liver; Male; Mice; Penicillamine; Poisoning; Thiazoles; Thiocarbamates; Thioctic Acid | 1974 |
Management of distalgesic poisoning.
Topics: Acetaminophen; Acetylcysteine; Cysteamine; Dextropropoxyphene; Drug Combinations; Humans; Liver | 1981 |
Mechanism of action of paracetamol protective agents in mice in vivo.
Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Animals; Buthionine Sulfoximine; Cysteamine; Cysteine; Glutathione; Liver; Male; Methionine; Methionine Sulfoximine; Mice; Mice, Inbred C3H | 1984 |
Paracetamol-induced acute renal failure.
Topics: Acetaminophen; Acute Kidney Injury; Adult; Cysteamine; Female; Humans | 1982 |
[Toxicology and therapy of paracetamol poisoning].
Topics: Acetaminophen; Acetylcysteine; Cysteamine; Drug Interactions; Ethanol; Gastric Lavage; Glutathione; Half-Life; Methionine; Phenobarbital; Poisoning | 1980 |
Effects of sulphur-containing compounds on paracetamol activation and covalent binding in a mouse hepatic microsomal system.
Topics: Acetaminophen; Acetylcysteine; Animals; Biotransformation; Cysteamine; In Vitro Techniques; Male; Methionine; Mice; Microsomes, Liver; Mixed Function Oxygenases; Sulfur; Tiopronin | 1980 |
An integrated approach to the study of chemically reactive metabolites of acetaminophen.
Topics: Acetaminophen; Animals; Antidotes; Biotransformation; Cricetinae; Cysteamine; Cysteine; Dose-Response Relationship, Drug; Glutathione; Liver; Mice; Necrosis; Rats | 1981 |
Treatment of severe acetaminophen poisoning with intravenous acetylcysteine.
Topics: Acetaminophen; Acetylcysteine; Administration, Oral; Cysteamine; Humans; Injections, Intravenous; Liver; Methionine | 1981 |
(Z)-3-(4-bromophenyl)-3-(3-pyridyl)allylamine as substrate for studies of myeloperoxidase activity.
Topics: Acetaminophen; Chlorides; Chromatography, Thin Layer; Cysteamine; Cysteine; Gas Chromatography-Mass Spectrometry; Hypochlorous Acid; Magnetic Resonance Spectroscopy; Parabens; Peroxidase; Phenylacetates; Phenylpropionates; Pyridazines; Spectrophotometry, Ultraviolet; Substrate Specificity; Zimeldine | 1995 |
Differential gene expression in mouse liver associated with the hepatoprotective effect of clofibrate.
Topics: Acetaminophen; Acyl-CoA Oxidase; Amidohydrolases; Animals; Anticholesteremic Agents; Cell Adhesion Molecules; Chemical and Drug Induced Liver Injury; Clofibrate; Cluster Analysis; Cystamine; Cysteamine; Enoyl-CoA Hydratase; Gene Expression Profiling; GPI-Linked Proteins; Liver; Liver Diseases; Malate Dehydrogenase; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Pantetheine; Pantothenic Acid; Peroxisome Proliferators; PPAR alpha; Proteasome Endopeptidase Complex; Reverse Transcriptase Polymerase Chain Reaction | 2007 |
Acrolein scavengers, cysteamine and N-benzylhydroxylamine, reduces the mouse liver damage after acetaminophen overdose.
Topics: Acetaminophen; Acrolein; Animals; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Cysteamine; Drug Overdose; Humans; Hydroxylamines; Liver; Mice; Mice, Inbred C57BL; Oxidative Stress; Reactive Oxygen Species | 2017 |