acetaminophen and cysteamine

acetaminophen has been researched along with cysteamine in 81 studies

Research

Studies (81)

TimeframeStudies, this research(%)All Research%
pre-199072 (88.89)18.7374
1990's2 (2.47)18.2507
2000's3 (3.70)29.6817
2010's4 (4.94)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Scott, CR; Stewart, MJ1
Douglas, AP; James, O; Lesna, M; Pulman, L; Roberts, SH; Smith, PA; Watson, AJ1
Douglas, AP; Hamlyn, AN; James, O1
Park, J; Prescott, LF; Proudfoot, AT2
Hughes, RD; Trewby, P; Williams, R1
Park, J; Prescott, LF; Proudfoot, AT; Smith, IJ; Sutherland, GR1
Barclay, JE; Stewart, MJ1
Brouwers, JR; Vermeij, P1
Adriaenssens, P; Ballantyne, A; Park, J; Prescott, LF; Proudfoot, AT1
Bhakthan, NM; Chiu, S1
Allain, P; Chaleil, D; Larra, F1
Harvey, FD; Levitt, TE1
Davis, M; Williams, R1
Ameer, B; Greenblatt, DJ1
Bennet, JR; Davis, M; Gazzard, BG; Hanid, MA; Hughes, RD; Murray-Lyon, IM; Trewby, PN; Williams, R1
Black, M2
van Zwieten, PA1
Adam, RD; Critchley, JA; Illingworth, RN; Prescott, LF; Proudfoot, AT; Stewart, MJ1
Gilbertson, AA; Hall, SM; Roberts, WO; Smith, JM; White, TA1
Prescott, LF; Proudfoot, AT; Stewart, MJ1
Peterson, RG; Rumack, BH1
Prescott, LF2
Cheung, TP; Parkin, GW; Rigby, RJ; Thomson, NM1
Austin, F; Carloss, H; Forrester, J; Fuson, T1
Emby, DJ; Fraser, BN1
Best, L; Krenzelok, EP; Manoguerra, AS1
Cameron, AJ; Szabo, S1
Forester, D1
Davis, M; Gazzard, BG; Goulding, R; Hughes, RD; Widdop, B; Williams, R1
Hart, FE; Willson, RA1
Birrell, R; Briggs, JD; Henry, DA; Knepil, J; Solomon, AE; Winchester, JF1
Douzeen, JM; Pikaar, SA; van Heijst, AN1
Crome, P; Vale, JA; Volans, GN; Widdop, P1
Moerland, J1
James, O1
Gazzard, BG; Hughes, RD; Murray-Lyon, IM; Williams, RS1
Labadarios, D; Williams, RS1
Penn, RG1
Bennett, JR; Chhibber, AD; Dordoni, B; Gazzard, BG; Hughes, RD; Murray-Lyon, IM; Williams, R1
Prescott, LF; Wright, N2
Matthew, H; Rumack, BH1
Alván, G; Evaldsson-Carlén, U; Mellström, B1
Brown, IR; Peterson, TC1
Peterson, MR; Peterson, TC; Williams, CN1
Gregus, Z; Klaassen, CD; Madhu, C1
Davis, M1
Hayashi, S; Nakai, T1
Jollow, DJ; Miller, MG1
Forrest, AR; Matthew, H; Newton, RW; Prescott, LF; Swainson, CP; Wright, N1
Goulding, R; Harvey, F1
Jollow, DJ; Keiser, H; Mitchell, JR; Potter, WZ; Thorgeirsson, SS1
Dordoni, B; Gazzard, BG; Hughes, RD; Portmann, B; Williams, R1
Schütt, A; Siegers, CP; Strubelt, O1
Gilbertson, AA; Smith, JM1
Crome, P; Hamlyn, AN; Lesna, M; Meredith, T; Record, CO; Smith, PA; Volans, GN; Watson, AJ1
Critchley, JA; Prescott, LF1
Birkett, DJ; Drew, R; Miners, JO1
Harris, AL1
Goulding, R; Meredith, TJ1
Pflüger, KH1
Davis, M; Smith, HM; Tredger, JM; Williams, R1
Gillette, JR1
Johansson, L; Lindvall, S; Rydell, G; Svensson, BE; Ulff, B1
Beger, RD; Holland, RD; Koza-Taylor, PH; Lawton, MP; Manautou, JE; Moffit, JS; Thibodeau, MS1
Koyama, R; Mizuta, R1
Brok, J; Buckley, NA; Chiew, AL; Gluud, C1

Reviews

9 review(s) available for acetaminophen and cysteamine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Acetaminophen.
    Annals of internal medicine, 1977, Volume: 87, Issue:2

    Topics: Acetaminophen; Analgesia; Animals; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Cysteamine; Double-Blind Method; Fever; Hemostasis; Humans; Kidney Diseases; Kinetics; Liver; Male; Methionine; Pain; Placebos

1977
Hepatotoxicity: pathogenesis and therapeutic intervention.
    Clinics in gastroenterology, 1979, Volume: 8, Issue:1

    Topics: Acetaminophen; Anabolic Agents; Androgens; Animals; Chemical and Drug Induced Liver Injury; Cysteamine; Cysteine; Erythromycin; Estrogens; Halothane; Humans; Isoniazid; Liver; Nitrofurantoin; Rifampin

1979
Protective agents for acetaminophen overdose.
    Seminars in liver disease, 1986, Volume: 6, Issue:2

    Topics: Acetaminophen; Acetylcysteine; Animals; Cell Membrane; Chemical and Drug Induced Liver Injury; Cimetidine; Cysteamine; Glucuronates; Glutathione; Humans; Inactivation, Metabolic; Lipid Peroxides; Liver; Methionine; Necrosis; Propylthiouracil

1986
[Therapy of toxic hepatitis].
    Nihon rinsho. Japanese journal of clinical medicine, 1985, Volume: 43, Issue:6

    Topics: Acetaminophen; Acetylcysteine; Adrenal Cortex Hormones; Age Factors; Aged; Animals; Chemical and Drug Induced Liver Injury; Cysteamine; Female; Humans; Male; Middle Aged; Prognosis; Sex Factors

1985
The treatment of acetaminophen poisoning.
    Annual review of pharmacology and toxicology, 1983, Volume: 23

    Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Antidotes; Aspartate Aminotransferases; Biotransformation; Chemical and Drug Induced Liver Injury; Cysteamine; Glutathione; Humans; Liver; Methionine; Necrosis; Sulfhydryl Compounds

1983
Acetaminophen hepatotoxicity.
    Gastroenterology, 1980, Volume: 78, Issue:2

    Topics: Acetaminophen; Acetylcysteine; Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Cysteamine; Cysteine; Glutathione; Hepatic Encephalopathy; Humans; Liver; Liver Function Tests; Methionine

1980
Paracetamol.
    Postgraduate medical journal, 1980, Volume: 56, Issue:657

    Topics: Acetaminophen; Acetylcysteine; Adult; Animals; Chemical and Drug Induced Liver Injury; Child; Cysteamine; Dextropropoxyphene; Humans; Infant; Kidney Diseases; Methionine

1980
Interventions for paracetamol (acetaminophen) overdose.
    The Cochrane database of systematic reviews, 2018, 02-23, Volume: 2

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antidotes; Charcoal; Cysteamine; Dimercaprol; Drug Overdose; Gastric Lavage; Humans; Intestinal Absorption; Liver Failure, Acute; Liver Transplantation; Methionine; Randomized Controlled Trials as Topic

2018

Trials

10 trial(s) available for acetaminophen and cysteamine

ArticleYear
Controlled trial of cysteamine in treatment of acute paracetamol (acetaminophen) poisoning.
    Lancet (London, England), 1976, Jan-17, Volume: 1, Issue:7951

    Topics: Acetaminophen; Acute Disease; Adult; Age Factors; Aged; Aspartate Aminotransferases; Bile Acids and Salts; Bilirubin; Clinical Trials as Topic; Cysteamine; Ferritins; Humans; Injections, Intravenous; Liver; Liver Function Tests; Prothrombin; Time Factors

1976
Acetaminophen.
    Annals of internal medicine, 1977, Volume: 87, Issue:2

    Topics: Acetaminophen; Analgesia; Animals; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Cysteamine; Double-Blind Method; Fever; Hemostasis; Humans; Kidney Diseases; Kinetics; Liver; Male; Methionine; Pain; Placebos

1977
Controlled trial of cysteamine and dimercaprol after paracetamol overdose.
    British medical journal, 1977, Nov-26, Volume: 2, Issue:6099

    Topics: Acetaminophen; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Cysteamine; Dimercaprol; Female; Humans; Male

1977
A controlled trial of cysteamine in the treatment of acute paracetamol poisoning.
    The Journal of international medical research, 1976, Volume: 4, Issue:4 Suppl

    Topics: Acetaminophen; Acute Disease; Adult; Cysteamine; Humans; Liver; Liver Function Tests; Suicide

1976
The use of cysteamine and dimercaprol.
    The Journal of international medical research, 1976, Volume: 4, Issue:4 Suppl

    Topics: Acetaminophen; Cysteamine; Dimercaprol; Humans; Liver; Liver Function Tests

1976
Proceedings: Controlled trial of cysteamine and dimercaprol in the prevention of liver damage after paracetamol overdose.
    Gut, 1975, Volume: 16, Issue:10

    Topics: Acetaminophen; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Cysteamine; Dimercaprol; Humans; Liver

1975
Letter: Treatment of paracetamol poisoning.
    Lancet (London, England), 1974, May-04, Volume: 1, Issue:7862

    Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Cysteamine; Humans; Injections, Intravenous; Poisoning; Prospective Studies; Rats; Time Factors; Vitamin E

1974
Letter: Cysteamine for paracetamol overdosage.
    Lancet (London, England), 1974, May-18, Volume: 1, Issue:7864

    Topics: Acetaminophen; Acetylcysteine; Blood Specimen Collection; Chemical and Drug Induced Liver Injury; Chromatography, Gas; Clinical Trials as Topic; Cysteamine; Dimercaprol; Humans; Penicillamine; Poisoning; Time Factors

1974
Letter: Treatment of paracetamol overdosage.
    Lancet (London, England), 1974, Jun-08, Volume: 1, Issue:7867

    Topics: Acetaminophen; Administration, Oral; Clinical Trials as Topic; Cysteamine; Humans; Methionine; Poisoning; Time Factors

1974
Methionine and cysteamine in paracetamol (acetaminophen) overdose, prospective controlled trial of early therapy.
    The Journal of international medical research, 1981, Volume: 9, Issue:3

    Topics: Acetaminophen; Amylases; Clinical Trials as Topic; Cysteamine; Humans; Kidney; Liver; Methionine; Myocardium; Prospective Studies

1981

Other Studies

63 other study(ies) available for acetaminophen and cysteamine

ArticleYear
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Letter: cysteamine treatment in paracetamol overdose.
    Lancet (London, England), 1975, Feb-22, Volume: 1, Issue:7904

    Topics: Acetaminophen; Adult; Alcohol Drinking; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cysteamine; Ethanol; Gastric Lavage; Humans; Liver Diseases; Male; Time Factors

1975
Liver damage after paracetamol overdose. Comparison of liver-function tests, fasting serum bile acids, and liver histology.
    Lancet (London, England), 1975, Sep-27, Volume: 2, Issue:7935

    Topics: Acetaminophen; Adolescent; Adult; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Cysteamine; Humans; Liver; Liver Function Tests; Middle Aged; Parenteral Nutrition

1975
Letter: Cysteamine for paracetamol poisoning.
    Lancet (London, England), 1976, Feb-14, Volume: 1, Issue:7955

    Topics: Acetaminophen; Cysteamine; Humans; Time Factors

1976
Letter: Cysteamine for paracetamol poisoning.
    Lancet (London, England), 1976, Mar-06, Volume: 1, Issue:7958

    Topics: Acetaminophen; Cysteamine; Humans; Time Factors

1976
Cysteamine, methionine, and penicillamine in the treatment of paracetamol poisoning.
    Lancet (London, England), 1976, Jul-17, Volume: 2, Issue:7977

    Topics: Acetaminophen; Acute Kidney Injury; Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Cysteamine; Drug Evaluation; Female; Humans; Liver Diseases; Male; Methionine; Middle Aged; Necrosis; Penicillamine; Poisoning; Time Factors

1976
Letter: Treatment of paracetamol overdose.
    Lancet (London, England), 1976, Aug-14, Volume: 2, Issue:7981

    Topics: Acetaminophen; Cysteamine; Drug Evaluation; Humans; Methionine; Suicide, Attempted

1976
Letter: Emergency estimation of plasma-paracetamol.
    Lancet (London, England), 1976, Aug-14, Volume: 2, Issue:7981

    Topics: Acetaminophen; Colorimetry; Cysteamine; Emergencies; Humans; Poison Control Centers

1976
Cysteamine injection for paracetamol poisoning.
    Lancet (London, England), 1976, Oct-30, Volume: 2, Issue:7992

    Topics: Acetaminophen; Cysteamine; Humans; Injections

1976
Treatment of paracetamol (acetaminophen) poisoning with N-acetylcysteine.
    Lancet (London, England), 1977, Aug-27, Volume: 2, Issue:8035

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Chemical and Drug Induced Liver Injury; Cysteamine; Drug Evaluation; Female; Follow-Up Studies; Humans; Infusions, Parenteral; Male; Methionine; Middle Aged

1977
Experimental acetaminophen-induced hepatic necrosis: biochemical and electron microscopic study of cysteamine protection.
    Laboratory investigation; a journal of technical methods and pathology, 1978, Volume: 39, Issue:3

    Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cricetinae; Cysteamine; Electron Transport; Lipid Metabolism; Liver Diseases; Male; Mesocricetus; Microscopy, Electron; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Necrosis; Peroxides

1978
[Radioprotective action of N-acetyl p. aminophenol in the mouse].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1975, Volume: 169, Issue:3

    Topics: Acetaminophen; Animals; Cell Survival; Cysteamine; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Gamma Rays; Injections, Intraperitoneal; Leukocytes; Male; Mice; Radiation Effects; Radiation-Protective Agents

1975
Experimental evaluation of paracetamol antidotes.
    The Journal of international medical research, 1976, Volume: 4, Issue:4 Suppl

    Topics: Acetaminophen; Animals; Antidotes; Bile; Cysteamine; Cysteine; Ditiocarb; Glutathione; Imidazoles; In Vitro Techniques; Liver; Methionine; Mice; Rats

1976
Therapeutic aspects of paracetamol overdose including management of acute liver failure.
    Acta pharmacologica et toxicologica, 1977, Volume: 41 Suppl 2

    Topics: Acetaminophen; Chemical and Drug Induced Liver Injury; Cysteamine; Humans; Tiopronin

1977
[Therapy of paracetamol poisoning].
    Nederlands tijdschrift voor geneeskunde, 1979, Feb-24, Volume: 123, Issue:8

    Topics: Acetaminophen; Acetylcysteine; Chemical and Drug Induced Liver Injury; Cysteamine; Humans; Methionine

1979
Intravenous N-acetylcystine: the treatment of choice for paracetamol poisoning.
    British medical journal, 1979, Nov-03, Volume: 2, Issue:6198

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Cysteamine; Female; Humans; Infusions, Parenteral; Kidney Diseases; Liver Diseases; Male; Methionine; Middle Aged; Risk; Time Factors

1979
Paracetamol overdosage.
    British medical journal, 1978, Jan-14, Volume: 1, Issue:6105

    Topics: Acetaminophen; Acetylcysteine; Cysteamine; Humans

1978
Late treatment of paracetamol poisoning with mercaptamine.
    British medical journal, 1978, Feb-11, Volume: 1, Issue:6109

    Topics: Acetaminophen; Acute Kidney Injury; Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Cysteamine; Female; Humans; Liver Diseases; Liver Function Tests; Male; Middle Aged; Time Factors

1978
Cysteamine or N-acetylcysteine for paracetamol poisoning?
    British medical journal, 1978, Apr-01, Volume: 1, Issue:6116

    Topics: Acetaminophen; Acetylcysteine; Cysteamine; Humans; Time Factors

1978
Toxicity of acetaminophen overdose.
    JACEP, 1978, Volume: 7, Issue:5

    Topics: Acetaminophen; Acetylcysteine; Cysteamine; Humans; Methionine

1978
The chief scientist reports ... prevention of hepatic necrosis following paracetamol overdosage.
    Health bulletin, 1978, Volume: 36, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Cysteamine; Female; Humans; Liver Diseases; Male; Methionine; Middle Aged; Scotland

1978
The treatment of paracetamol overdose with charcoal haemoperfusion and cysteamine.
    The Medical journal of Australia, 1978, Apr-08, Volume: 1, Issue:7

    Topics: Acetaminophen; Charcoal; Cysteamine; Female; Hemoperfusion; Humans; Middle Aged; Poisoning

1978
Acute acetaminophen intoxication.
    Southern medical journal, 1978, Volume: 71, Issue:8

    Topics: Acetaminophen; Acetylcysteine; Adult; Chemical and Drug Induced Liver Injury; Cysteamine; Female; Humans; Liver; Male; Methionine; Suicide, Attempted

1978
Hepatotoxicity of paracetamol enhanced by ingestion of alcohol: report of two cases.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1977, Feb-12, Volume: 51, Issue:7

    Topics: Acetaminophen; Adult; Alcoholism; Chemical and Drug Induced Liver Injury; Cysteamine; Female; Humans; Liver Diseases; Male; Middle Aged; Necrosis

1977
Acetaminophen toxity.
    American journal of hospital pharmacy, 1977, Volume: 34, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Adult; Chemical and Drug Induced Liver Injury; Cysteamine; Humans; Liver; Liver Diseases; Liver Function Tests; Male; Necrosis; Sulfhydryl Compounds

1977
Acetaminophen (paracetamol) poisoning: gastrointestinal side effects of cysteamine and their possible cause and treatment.
    Mayo Clinic proceedings, 1977, Volume: 52, Issue:6

    Topics: Acetaminophen; Antidotes; Cysteamine; Humans; Poisoning

1977
Acetaminophen hepatotoxicity.
    Mayo Clinic proceedings, 1977, Volume: 52, Issue:6

    Topics: Acetaminophen; Chemical and Drug Induced Liver Injury; Cysteamine; Humans; Methionine

1977
Early prediction of the outcome of a paracetamol overdose based on an analysis of 163 patients.
    Postgraduate medical journal, 1977, Volume: 53, Issue:619

    Topics: Acetaminophen; Bilirubin; Chemical and Drug Induced Liver Injury; Cysteamine; Humans; Liver Diseases; Liver Function Tests; Prognosis

1977
Treatment of acute paracetamol poisoning.
    British medical journal, 1977, Aug-20, Volume: 2, Issue:6085

    Topics: Acetaminophen; Chemical and Drug Induced Liver Injury; Cysteamine; Humans; Liver Diseases

1977
In vitro spectral alteration of hepatic cytochrome P-450 by experimental drug injury.
    Research communications in chemical pathology and pharmacology, 1977, Volume: 17, Issue:4

    Topics: Acetaminophen; Animals; Buffers; Chemical and Drug Induced Liver Injury; Cysteamine; Cysteine; Cytochrome P-450 Enzyme System; Dimethyl Sulfoxide; Enzyme Induction; Glutathione; In Vitro Techniques; Liver Diseases; Male; Methionine; Microsomes, Liver; Phenobarbital; Rats; Solvents

1977
Therapeutic comparison of thiol compounds in severe paracetamol poisoning.
    Annals of clinical biochemistry, 1977, Volume: 14, Issue:4

    Topics: Acetaminophen; Adolescent; Adult; Amino Acids; Cysteamine; Female; Humans; Liver Function Tests; Male; Substance-Related Disorders

1977
[Paracetamol poisoning].
    Nederlands tijdschrift voor geneeskunde, 1976, Jul-03, Volume: 120, Issue:27

    Topics: Acetaminophen; Administration, Oral; Adult; Cysteamine; Female; Humans; Injections, Intravenous; Legislation, Drug; Methionine; Netherlands; Poisoning

1976
Letter: Toxicity of paracetamol in children.
    British medical journal, 1976, Aug-21, Volume: 2, Issue:6033

    Topics: Acetaminophen; Child; Child, Preschool; Cysteamine; Humans; Methionine

1976
[Paracetamol poisoning--liver damage. Therapy or prevention?].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1976, Aug-30, Volume: 96, Issue:24

    Topics: Acetaminophen; Chemical and Drug Induced Liver Injury; Cysteamine; Glutathione; Humans; Liver

1976
Cysteamine, L-methionine and D-penicillamine in paracetamol poisoning.
    The Journal of international medical research, 1976, Volume: 4, Issue:4 Suppl

    Topics: Acetaminophen; Cysteamine; Humans; Methionine; Penicillamine

1976
Paracetamol, alpha-mercaptopropionyl glycine and some observations on the toxicity of protective agents.
    The Journal of international medical research, 1976, Volume: 4, Issue:4 Suppl

    Topics: Acetaminophen; Amino Acids, Sulfur; Animals; Cysteamine; Glutathione; Liver; Male; Mice; Tiopronin

1976
A theoretical approach to the management of paracetamol overdosage.
    The Journal of international medical research, 1976, Volume: 4, Issue:4 Suppl

    Topics: Acetaminophen; Charcoal; Cysteamine; Drug Therapy; Glutathione; Humans; Perfusion; Propranolol; Renal Dialysis; Sulfhydryl Compounds

1976
Editorial: Paracetamol and the liver.
    The New Zealand medical journal, 1976, Mar-10, Volume: 83, Issue:559

    Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cysteamine; Humans; Liver; Liver Diseases; Necrosis

1976
Letter: Treatment of paracetamol poisoning.
    British medical journal, 1975, May-10, Volume: 2, Issue:5966

    Topics: Acetaminophen; Cysteamine; Humans; Poisoning

1975
Acetaminophen poisoning and toxicity.
    Pediatrics, 1975, Volume: 55, Issue:6

    Topics: Acetaminophen; Agranulocytosis; Chemical and Drug Induced Liver Injury; Cysteamine; Humans; Hypoglycemia; Kidney Papillary Necrosis; Liver; Necrosis; Pericarditis; Poison Control Centers; Poisoning; Prognosis; Skin Manifestations; Substance-Related Disorders

1975
[Paracetamol poisoning--clinical picture and treatment possibilities].
    Lakartidningen, 1976, Apr-28, Volume: 73, Issue:18

    Topics: Acetaminophen; Adult; Antidotes; Chemical and Drug Induced Liver Injury; Cysteamine; Cysteine; Drug Synergism; Female; Humans; Liver; Methionine; Oxazepam

1976
Cysteamine in combination with N-acetylcysteine prevents acetaminophen-induced hepatotoxicity.
    Canadian journal of physiology and pharmacology, 1992, Volume: 70, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Animals; Cysteamine; Cytochrome P-450 Enzyme System; Drug Interactions; Liver; Male; Mice

1992
The role of heme oxygenase and aryl hydrocarbon hydroxylase in the protection by cysteamine from acetaminophen hepatotoxicity.
    Toxicology and applied pharmacology, 1989, Mar-01, Volume: 97, Issue:3

    Topics: Acetaminophen; Animals; Aryl Hydrocarbon Hydroxylases; Cysteamine; Cytochrome P-450 Enzyme Inhibitors; Heme Oxygenase (Decyclizing); Liver; Male; Mixed Function Oxygenases; Rats; Rats, Inbred Strains

1989
Biliary excretion of acetaminophen-glutathione as an index of toxic activation of acetaminophen: effect of chemicals that alter acetaminophen hepatotoxicity.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:3

    Topics: Acetaminophen; Animals; Antioxidants; Bile; Biotransformation; Cricetinae; Cysteamine; Liver; Male; Mesocricetus; Methylcholanthrene; Phenobarbital; Prostaglandin Antagonists

1989
Acetaminophen hepatotoxicity: studies on the mechanism of cysteamine protection.
    Toxicology and applied pharmacology, 1986, Mar-30, Volume: 83, Issue:1

    Topics: Acetaminophen; Animals; Cricetinae; Cysteamine; In Vitro Techniques; Inactivation, Metabolic; Kinetics; Liver; Male; Mesocricetus; Necrosis

1986
Successful treatment of severe paracetamol overdosage with cysteamine.
    Lancet (London, England), 1974, Apr-06, Volume: 1, Issue:7858

    Topics: Acetaminophen; Adolescent; Adult; Bilirubin; Blood Cell Count; Blood Urea Nitrogen; Chemical and Drug Induced Liver Injury; Chromatography, Gas; Cysteamine; Dose-Response Relationship, Drug; Female; Humans; Injections, Intravenous; Liver Diseases; Middle Aged; Poisoning; Prothrombin Time; Spectrophotometry; Suicide

1974
Letter: Action of cysteamine in paracetamol poisoning.
    Lancet (London, England), 1974, Nov-02, Volume: 2, Issue:7888

    Topics: Acetaminophen; Animals; Biotransformation; Cysteamine; Liver; Oxidation-Reduction; Perfusion; Rats

1974
Letter: B.A.L. in paracetamol poisoning.
    Lancet (London, England), 1974, Oct-05, Volume: 2, Issue:7884

    Topics: Acetaminophen; Chemical and Drug Induced Liver Injury; Cysteamine; Dimercaprol; Drug Evaluation; Humans; Injections, Intramuscular

1974
Acetaminophen-induced hepatic injury: protective role of glutathione in man and rationale for therapy.
    Clinical pharmacology and therapeutics, 1974, Volume: 16, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Adult; Amobarbital; Animals; Chemical and Drug Induced Liver Injury; Chromatography, Paper; Cysteamine; Cytochrome P-450 Enzyme System; Desipramine; Dimercaprol; Dose-Response Relationship, Drug; Enzyme Induction; Female; Glutathione; Humans; Indicators and Reagents; Liver; Male; Mass Spectrometry; Methyltransferases; Mice; Microsomes, Liver; Phenobarbital; Protein Binding; Proteins; Sulfhydryl Compounds; Time Factors; Tritium

1974
Protection of rats against the hepatotoxic effect of paracetamol.
    British journal of experimental pathology, 1974, Volume: 55, Issue:6

    Topics: Acetaminophen; Administration, Oral; Animals; Cysteamine; Cytochrome P-450 Enzyme System; Drug Interactions; Glutathione; Injections, Intraperitoneal; Liver; Male; Microsomes, Liver; Necrosis; Propranolol; Rats; Thioctic Acid; Vitamin E

1974
The curative effects of cysteamine, cysteine, and dithiocarb in experimental paracetamol poisoning.
    Archives of toxicology, 1974, Volume: 33, Issue:1

    Topics: Acetaminophen; Alcohols; Animals; Carboxylic Acids; Chemical and Drug Induced Liver Injury; Cysteamine; Cysteine; Dimercaprol; Enzymes; Flavonoids; Glutathione; Lethal Dose 50; Liver; Male; Mice; Penicillamine; Poisoning; Thiazoles; Thiocarbamates; Thioctic Acid

1974
Management of distalgesic poisoning.
    Lancet (London, England), 1981, Jan-03, Volume: 1, Issue:8210

    Topics: Acetaminophen; Acetylcysteine; Cysteamine; Dextropropoxyphene; Drug Combinations; Humans; Liver

1981
Mechanism of action of paracetamol protective agents in mice in vivo.
    Biochemical pharmacology, 1984, Oct-01, Volume: 33, Issue:19

    Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Animals; Buthionine Sulfoximine; Cysteamine; Cysteine; Glutathione; Liver; Male; Methionine; Methionine Sulfoximine; Mice; Mice, Inbred C3H

1984
Paracetamol-induced acute renal failure.
    British medical journal (Clinical research ed.), 1982, Mar-13, Volume: 284, Issue:6318

    Topics: Acetaminophen; Acute Kidney Injury; Adult; Cysteamine; Female; Humans

1982
[Toxicology and therapy of paracetamol poisoning].
    Der Internist, 1980, Volume: 21, Issue:12

    Topics: Acetaminophen; Acetylcysteine; Cysteamine; Drug Interactions; Ethanol; Gastric Lavage; Glutathione; Half-Life; Methionine; Phenobarbital; Poisoning

1980
Effects of sulphur-containing compounds on paracetamol activation and covalent binding in a mouse hepatic microsomal system.
    Toxicology letters, 1980, Volume: 5, Issue:5

    Topics: Acetaminophen; Acetylcysteine; Animals; Biotransformation; Cysteamine; In Vitro Techniques; Male; Methionine; Mice; Microsomes, Liver; Mixed Function Oxygenases; Sulfur; Tiopronin

1980
An integrated approach to the study of chemically reactive metabolites of acetaminophen.
    Archives of internal medicine, 1981, Feb-23, Volume: 141, Issue:3 Spec No

    Topics: Acetaminophen; Animals; Antidotes; Biotransformation; Cricetinae; Cysteamine; Cysteine; Dose-Response Relationship, Drug; Glutathione; Liver; Mice; Necrosis; Rats

1981
Treatment of severe acetaminophen poisoning with intravenous acetylcysteine.
    Archives of internal medicine, 1981, Feb-23, Volume: 141, Issue:3 Spec No

    Topics: Acetaminophen; Acetylcysteine; Administration, Oral; Cysteamine; Humans; Injections, Intravenous; Liver; Methionine

1981
(Z)-3-(4-bromophenyl)-3-(3-pyridyl)allylamine as substrate for studies of myeloperoxidase activity.
    Chemico-biological interactions, 1995, Volume: 94, Issue:2

    Topics: Acetaminophen; Chlorides; Chromatography, Thin Layer; Cysteamine; Cysteine; Gas Chromatography-Mass Spectrometry; Hypochlorous Acid; Magnetic Resonance Spectroscopy; Parabens; Peroxidase; Phenylacetates; Phenylpropionates; Pyridazines; Spectrophotometry, Ultraviolet; Substrate Specificity; Zimeldine

1995
Differential gene expression in mouse liver associated with the hepatoprotective effect of clofibrate.
    Toxicology and applied pharmacology, 2007, Jul-15, Volume: 222, Issue:2

    Topics: Acetaminophen; Acyl-CoA Oxidase; Amidohydrolases; Animals; Anticholesteremic Agents; Cell Adhesion Molecules; Chemical and Drug Induced Liver Injury; Clofibrate; Cluster Analysis; Cystamine; Cysteamine; Enoyl-CoA Hydratase; Gene Expression Profiling; GPI-Linked Proteins; Liver; Liver Diseases; Malate Dehydrogenase; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Pantetheine; Pantothenic Acid; Peroxisome Proliferators; PPAR alpha; Proteasome Endopeptidase Complex; Reverse Transcriptase Polymerase Chain Reaction

2007
Acrolein scavengers, cysteamine and N-benzylhydroxylamine, reduces the mouse liver damage after acetaminophen overdose.
    The Journal of veterinary medical science, 2017, Jan-10, Volume: 78, Issue:12

    Topics: Acetaminophen; Acrolein; Animals; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Cysteamine; Drug Overdose; Humans; Hydroxylamines; Liver; Mice; Mice, Inbred C57BL; Oxidative Stress; Reactive Oxygen Species

2017