acetaminophen has been researched along with curcumin in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (6.67) | 18.2507 |
| 2000's | 3 (10.00) | 29.6817 |
| 2010's | 19 (63.33) | 24.3611 |
| 2020's | 6 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Feng, F; He, S; Jiang, H; Jiang, X; Liu, W; Qu, W; Sun, H; Zhou, J | 1 |
| Donatus, IA; Vermeulen, NP | 1 |
| Cashman, JR; Court, MH; Ghirmai, S; Volak, LP | 1 |
| Cekmen, M; Ersoz, C; Ilbey, YO; Ozbek, E; Simsek, A; Somay, A | 1 |
| Girish, C; Jayanthi, S; Koner, BC; Pradhan, SC; Rajesh, B; Ramachandra Rao, K | 1 |
| Dehpour, AR; Javidnia, K; Kheradpezhouh, E; Miri, R; Monabati, A; Noorafshan, A; Panjehshahin, MR | 1 |
| Abdelmegid, LA; El-Guendi, MI; Omar, SA; Yousef, MI | 1 |
| Fong, YK; Li, CR; Lin, G; Wang, S; Wo, SK; Zhang, L; Zhou, L; Zuo, Z | 1 |
| Brooks, T; Bulku, E; Cicero, L; Halley, H; Ray, SD; Stohs, SJ | 1 |
| Badmaev, V; Court, MH; Greenblatt, DJ; Hanley, MJ; Harmatz, JS; Hazarika, S; Majeed, M; Masse, G; Volak, LP | 1 |
| Klaikeaw, N; Somanawat, K; Thong-Ngam, D | 1 |
| Chen, JB; Chen, XM; Gong, Q; Li, G; Nie, H; Qin, XY; Wang, C; Xu, Z | 1 |
| Chen, SM; Devadas, B; Rajkumar, M | 1 |
| Abdo Nassan, M; Ismail, TA; Soliman, MM | 1 |
| Barritt, GJ; Kheradpezhouh, E; Rychkov, GY | 1 |
| Eugenio-Pérez, D; Fernández-Rojas, B; Granados-Castro, LF; Hernández-Pando, R; León-Contreras, JC; Medina-Campos, ON; Pedraza-Chaverri, J; Pinzón, E; Rodríguez-Rangel, DS | 1 |
| Feng, ZM; Jiang, JS; Li, L; Xu, K; Yang, YN; Zang, CX; Zhang, PC | 1 |
| Chen, JF; Gu, JY; Huang, S; Liu, JJ; Luo, DD; Su, ZR; Sun, ZH; Xie, JH; Zhang, ZB; Zhuo, JY | 1 |
| Khan, H; Nabavi, SM; Ullah, H | 1 |
| Ahmed, AAH; Ahmed, AM; Al-Matrafi, TA; Al-Saggaf, S; Alqahtani, HM; AlRabiah, A; Arafah, MM; Atteya, M; Mohammad, RAT; Shereef, SH | 1 |
| Barreto, GE; Beiraghdar, F; Motaharinia, J; Panahi, Y; Sahebkar, A | 1 |
| Ahmad, MM; Fawzy, A; Rezk, NA; Sabry, M | 1 |
| Barai, M; Tomassone, MS; Winkler, JS | 1 |
| Dzhaubermezov, M; Ekomasova, N; Kharkov, V; Khitrinskaya, I; Khusnutdinova, E; Kolesnikov, N; Litvinov, S; Maksimova, N; Markov, A; Marusin, A; Radzhabov, M; Shtygasheva, O; Stepanov, V; Sukhomyasova, A; Swarovskaya, M; Zarubin, A | 1 |
| Hussein, RM; Kandeil, MA; Khallaf, RA; Mohammed, NA | 1 |
| Babu, RS; Kumar, KK; Kumar, PS; M, D; Narayanan, SS | 1 |
| Damayanti, IP; Mahati, E; Nugroho, T; Suhartono, S; Suryono, S; Susanto, H; Susilaningsih, N; Suwondo, A | 1 |
| Agarwal, R; Shukla, GS | 1 |
| Chawla, R; Chawla, S; Dhal, A; Hasan, N; Kalra, BS; Nirmal, K; Singhal, S | 1 |
| Baek, S; Ha, I; Hong, J; Jeon, W; Kim, H; Lee, J; Lee, Y; Yeo, C | 1 |
3 review(s) available for acetaminophen and curcumin
| Article | Year |
|---|---|
Rational Design of Multitarget-Directed Ligands: Strategies and Emerging Paradigms.
Topics: Animals; Drug Combinations; Drug Delivery Systems; Drug Design; Humans; Ligands | 2019 |
Mechanistic insights of hepatoprotective effects of curcumin: Therapeutic updates and future prospects.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Curcumin; Diethylnitrosamine; Hexachlorocyclohexane; Humans; Liver; Metals, Heavy; Oxidative Stress; Protective Agents | 2019 |
Efficacy of curcumin on prevention of drug-induced nephrotoxicity: A review of animal studies.
Topics: Acetaminophen; Acute Kidney Injury; Administration, Oral; Animals; Anti-Inflammatory Agents; Antioxidants; Biological Availability; Curcuma; Curcumin; Drug Administration Schedule; Humans; Kidney; Kidney Function Tests; Methotrexate; Rats | 2019 |
2 trial(s) available for acetaminophen and curcumin
| Article | Year |
|---|---|
Effect of a herbal extract containing curcumin and piperine on midazolam, flurbiprofen and paracetamol (acetaminophen) pharmacokinetics in healthy volunteers.
Topics: Acetaminophen; Alkaloids; Analgesics, Non-Narcotic; Area Under Curve; Benzodioxoles; Chromatography, High Pressure Liquid; Cross-Over Studies; Curcuma; Curcumin; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Double-Blind Method; Drug Interactions; Enzyme Inhibitors; Flurbiprofen; Half-Life; Humans; Hypnotics and Sedatives; Midazolam; Piperidines; Plant Extracts; Polyunsaturated Alkamides | 2013 |
Bioavailable turmeric extract for knee osteoarthritis: a randomized, non-inferiority trial versus paracetamol.
Topics: Acetaminophen; Adult; Curcuma; Double-Blind Method; Female; Humans; India; Male; Middle Aged; Osteoarthritis, Knee; Pain Measurement; Plant Extracts; Prospective Studies; Treatment Outcome | 2021 |
25 other study(ies) available for acetaminophen and curcumin
| Article | Year |
|---|---|
Cytotoxic and cytoprotective activities of curcumin. Effects on paracetamol-induced cytotoxicity, lipid peroxidation and glutathione depletion in rat hepatocytes.
Topics: Acetaminophen; Animals; Catechols; Cells, Cultured; Curcumin; Glutathione; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Male; Methylcholanthrene; Rats; Rats, Inbred Strains | 1990 |
Curcuminoids inhibit multiple human cytochromes P450, UDP-glucuronosyltransferase, and sulfotransferase enzymes, whereas piperine is a relatively selective CYP3A4 inhibitor.
Topics: Acetaminophen; Alkaloids; Benzodioxoles; Chromatography, High Pressure Liquid; Curcumin; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Glucuronosyltransferase; Humans; Liver; Piperidines; Polyunsaturated Alkamides; Recombinant Proteins; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Sulfotransferases | 2008 |
Curcumin prevents oxidative renal damage induced by acetaminophen in rats.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Catalase; Curcumin; Glutathione; Glutathione Peroxidase; Kidney Diseases; Male; Oxidative Stress; Protective Agents; Rats; Rats, Wistar; Superoxide Dismutase | 2009 |
Hepatoprotective activity of picroliv, curcumin and ellagic acid compared to silymarin on paracetamol induced liver toxicity in mice.
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cinnamates; Curcumin; Ellagic Acid; Female; Glycosides; Lipid Peroxidation; Liver; Male; Mice; Oxidative Stress; Phytotherapy; Silymarin; Sleep; Vanillic Acid | 2009 |
Curcumin protects rats against acetaminophen-induced hepatorenal damages and shows synergistic activity with N-acetyl cysteine.
Topics: Acetaminophen; Acetylcysteine; Animals; Biomarkers; Catalase; Curcumin; Drug Synergism; Glutathione Peroxidase; Kidney; Kidney Diseases; Liver; Liver Diseases; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Sprague-Dawley; Serologic Tests | 2010 |
Potential protective effects of quercetin and curcumin on paracetamol-induced histological changes, oxidative stress, impaired liver and kidney functions and haematotoxicity in rat.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Curcumin; Glutathione; Hematologic Diseases; Hematologic Tests; Kidney; Liver; Male; Necrosis; Oxidative Stress; Oxidoreductases; Quercetin; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances | 2010 |
In vitro and in situ evaluation of herb-drug interactions during intestinal metabolism and absorption of baicalein.
Topics: Acetaminophen; Administration, Oral; Alkaloids; Animals; Benzodioxoles; Biotransformation; Caco-2 Cells; Catechin; Chromatography, Liquid; Curcumin; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Flavanones; Glucuronides; Herb-Drug Interactions; Humans; Intestinal Absorption; Jejunum; Male; Medicine, Chinese Traditional; Perfusion; Piperidines; Plant Roots; Plants, Medicinal; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Scutellaria baicalensis; Sulfates; Tandem Mass Spectrometry | 2012 |
Curcumin exposure modulates multiple pro-apoptotic and anti-apoptotic signaling pathways to antagonize acetaminophen-induced toxicity.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Antioxidants; Apoptosis; Blotting, Western; Chemical and Drug Induced Liver Injury; Curcumin; DNA Fragmentation; Gene Expression; Lipid Peroxidation; Male; Mice; Oxidative Stress; Signal Transduction | 2012 |
Curcumin attenuated paracetamol overdose induced hepatitis.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Curcumin; Drug Evaluation, Preclinical; Drug Overdose; Glutathione; Interleukin-12; Interleukin-18; Liver; Male; Malondialdehyde; Mice; Phytotherapy; Plant Extracts; Transaminases | 2013 |
Curcumin protects against acetaminophen-induced apoptosis in hepatic injury.
Topics: Acetaminophen; Alanine Transaminase; Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Biomarkers; Chemical and Drug Induced Liver Injury; Curcumin; Cytoprotection; Disease Models, Animal; Hepatocytes; Lipid Peroxidation; Liver; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Necrosis; Oxidative Stress; Protective Agents; Proto-Oncogene Proteins c-bcl-2; Superoxide Dismutase | 2013 |
Electropolymerization of curcumin on glassy carbon electrode and its electrocatalytic application for the voltammetric determination of epinephrine and p-acetoaminophenol.
Topics: Acetaminophen; Carbon; Catalysis; Curcumin; Electrochemical Techniques; Electrodes; Epinephrine; Glass; Polymerization | 2014 |
Immunohistochemical and molecular study on the protective effect of curcumin against hepatic toxicity induced by paracetamol in Wistar rats.
Topics: Acetaminophen; Acute-Phase Proteins; Analgesics, Non-Narcotic; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Curcuma; Curcumin; Cytokines; Gene Expression; Hepatitis; Interleukin-1beta; Interleukin-8; Kidney; Liver; Male; Matrix Metalloproteinase 8; Necrosis; Neutrophil Infiltration; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Rats, Wistar; Tumor Necrosis Factor-alpha | 2014 |
Curcumin inhibits activation of TRPM2 channels in rat hepatocytes.
Topics: Acetaminophen; Animals; Cells, Cultured; Curcumin; Gene Expression Regulation; HEK293 Cells; Hepatocytes; Humans; Hydrogen Peroxide; Oxidative Stress; Rats; TRPM Cation Channels | 2016 |
Curcumin prevents paracetamol-induced liver mitochondrial alterations.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Curcumin; Disease Models, Animal; Dose-Response Relationship, Drug; Liver Function Tests; Male; Membrane Potential, Mitochondrial; Mice, Inbred Strains; Mitochondria, Liver; Oxygen Consumption; Protective Agents | 2016 |
Bioactive Sesquiterpenoid and Polyacetylene Glycosides from Atractylodes lancea.
Topics: Acetaminophen; Atractylodes; Biphenyl Compounds; Curcumin; Glycosides; Hep G2 Cells; Humans; Lipopolysaccharides; Liver; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Polyynes; Rhizome; Sesquiterpenes; Structure-Activity Relationship | 2016 |
Tetrahydrocurcumin and octahydrocurcumin, the primary and final hydrogenated metabolites of curcumin, possess superior hepatic-protective effect against acetaminophen-induced liver injury: Role of CYP2E1 and Keap1-Nrf2 pathway.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Curcumin; Cytochrome P-450 CYP2E1; Humans; Hydrogenation; Kelch-Like ECH-Associated Protein 1; Liver; Male; Mice; NF-E2-Related Factor 2; Oxidative Stress; Protective Agents; Signal Transduction | 2019 |
Thymoquinone and curcumin modify inducible nitric oxide synthase, caspase 3, and thioredoxin immunohistochemical expression in acetaminophen hepatotoxicity.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Benzoquinones; Bilirubin; Caspase 3; Curcumin; Glutathione; Immunohistochemistry; Liver; Liver Diseases; Male; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Superoxide Dismutase; Thioredoxins | 2019 |
Protective effects of curcumin and silymarin against paracetamol induced hepatotoxicity in adult male albino rats.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Curcumin; Drug Synergism; Immunohistochemistry; Liver; Liver Failure, Acute; Male; Oxidants; Oxidative Stress; Plant Extracts; PPAR gamma; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Silymarin | 2019 |
Dual drug-loaded biodegradable Janus particles for simultaneous co-delivery of hydrophobic and hydrophilic compounds.
Topics: Acetaminophen; Biocompatible Materials; Curcumin; Diffusion; Drug Delivery Systems; Drug Liberation; Emulsions; Hydrophobic and Hydrophilic Interactions; Naproxen; Oils; Particle Size; Pharmaceutical Preparations; Polyesters; Polylactic Acid-Polyglycolic Acid Copolymer; Quercetin; Solvents; Spectrophotometry, Ultraviolet; Water | 2019 |
Structural Variability, Expression Profile, and Pharmacogenetic Properties of TMPRSS2 Gene as a Potential Target for COVID-19 Therapy.
Topics: Acetaminophen; Angiotensin-Converting Enzyme 2; Asia; Basigin; COVID-19; COVID-19 Drug Treatment; Curcumin; Europe; Exons; Gene Expression Regulation, Enzymologic; Gene Frequency; Genetic Predisposition to Disease; Genetic Variation; Humans; MicroRNAs; Molecular Targeted Therapy; Mutation, Missense; Pharmacogenomic Testing; Protein Interaction Mapping; Receptors, Virus; SARS-CoV-2; Serine Endopeptidases; Single-Cell Analysis; Spike Glycoprotein, Coronavirus | 2020 |
Evaluation of the hepatoprotective effect of curcumin-loaded solid lipid nanoparticles against paracetamol overdose toxicity
Topics: Acetaminophen; Acetylcysteine; Animals; Curcumin; Liposomes; Nanoparticles; Nitric Oxide Synthase Type II; Rats; Rats, Wistar | 2022 |
Green synthesis of curcumin-silver nanoparticle and its modified electrode assisted amperometric sensor for the determination of paracetamol.
Topics: Acetaminophen; Curcumin; Electrochemical Techniques; Electrodes; Humans; Metal Nanoparticles; Silver | 2022 |
The Effect of Curcumin Nanoparticles on Paracetamol-induced Liver Injury in Male Wistar Rats.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury, Chronic; Curcumin; Male; Nanoparticles; Rats; Rats, Wistar; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2023 |
Potential role of cerebral glutathione in the maintenance of blood-brain barrier integrity in rat.
Topics: Acetaminophen; Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Blood-Brain Barrier; Brain; Curcuma; Glutathione; Ketones; Liver; Male; Maleates; Plant Extracts; Rats; Rats, Inbred Strains; Vitamin E | 1999 |
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Curcuma; Heme Oxygenase-1; Liver; Mice; Mice, Inbred C57BL; Oxidative Stress; Plant Extracts; Signal Transduction; Sirtuin 1 | 2023 |